Guy Sauvageau - Publications

Affiliations: 
Molecular Biology Université de Montréal, Montréal, Canada 
Area:
Molecular Biology, Cell Biology

165 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Lehnertz B, Chagraoui J, MacRae T, Tomellini E, Corneau S, Mayotte N, Boivin I, Durand A, Gracias D, Sauvageau G. HLF Expression Defines the Human Hematopoietic Stem Cell State. Blood. PMID 34499717 DOI: 10.1182/blood.2021010745  1
2021 Gavory G, Baril C, Laberge G, Bidla G, Koonpaew S, Sonea T, Sauvageau G, Therrien M. A genetic screen in Drosophila uncovers the multifaceted properties of the NUP98-HOXA9 oncogene. Plos Genetics. 17: e1009730. PMID 34383740 DOI: 10.1371/journal.pgen.1009730  1
2021 Herbrich S, Baran N, Cai T, Weng C, Aitken MJL, Post SM, Henderson J, Shi C, Richard-Carpentier G, Sauvageau G, Baggerly K, Al-Atrash G, Davis RE, Daver N, Zha D, et al. Overexpression of CD200 is a Stem Cell-Specific Mechanism of Immune Evasion in AML. Journal For Immunotherapy of Cancer. 9. PMID 34326171 DOI: 10.1136/jitc-2021-002968  1
2021 Supper E, Rudat S, Iyer V, Droop A, Wong K, Spinella JF, Thomas P, Sauvageau G, Adams DJ, Wong CC. Cut-like homeobox 1 (CUX1) tumor suppressor gene haploinsufficiency induces apoptosis evasion to sustain myeloid leukemia. Nature Communications. 12: 2482. PMID 33931647 DOI: 10.1038/s41467-021-22750-8  0.01
2021 Ehx G, Larouche JD, Durette C, Laverdure JP, Hesnard L, Vincent K, Hardy MP, Thériault C, Rulleau C, Lanoix J, Bonneil E, Feghaly A, Apavaloaei A, Noronha N, Laumont CM, ... ... Sauvageau G, et al. Atypical acute myeloid leukemia-specific transcripts generate shared and immunogenic MHC class-I-associated epitopes. Immunity. PMID 33740418 DOI: 10.1016/j.immuni.2021.03.001  1
2021 Moison C, Chagraoui J, Caron MC, Gagné JP, Coulombe Y, Poirier GG, Masson JY, Sauvageau G. Zinc finger protein E4F1 cooperates with PARP-1 and BRG1 to promote DNA double-strand break repair. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33692124 DOI: 10.1073/pnas.2019408118  1
2021 Chagraoui J, Girard S, Spinella JF, Simon L, Bonneil E, Mayotte N, MacRae T, Coulombe-Huntington J, Bertomeu T, Moison C, Tomellini E, Thibault P, Tyers M, Marinier A, Sauvageau G. UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex. Cell Stem Cell. 28: 48-62.e6. PMID 33417871 DOI: 10.1016/j.stem.2020.12.002  1
2020 Dumont-Lagacé M, Li Q, Tanguay M, Chagraoui J, Kientega T, Cardin GB, Brasey A, Trofimov A, Carli C, Ahmad I, Bambace NM, Bernard L, Kiss TL, Roy J, Roy DC, ... ... Sauvageau G, et al. UM171-expanded cord blood transplants support robust T cell reconstitution with low rates of severe infections. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. PMID 33022376 DOI: 10.1016/j.bbmt.2020.09.031  1
2020 LeBlanc R, Claveau JS, Ahmad I, Delisle JS, Bambace N, Bernard L, Cohen S, Kiss T, Lachance S, Landais S, Roy DC, Sauvageau G, Roy J. Newly diagnosed multiple myeloma patients treated with tandem auto-allogeneic stem cell transplant have better overall survival with similar outcomes at time of relapse compared to patients who received autologous transplant only. Clinical Transplantation. e14099. PMID 32981146 DOI: 10.1111/ctr.14099  1
2020 Claveau JS, Cohen S, Ahmad I, Delisle JS, Kiss T, Lachance S, Sauvageau G, Busque L, Brito RM, Bambace N, Bernard L, Claude Roy D, Roy J. Single UM171-expanded cord blood transplant can cure severe idiopathic aplastic anemia in absence of suitable donors. European Journal of Haematology. PMID 32749758 DOI: 10.1111/Ejh.13504  1
2020 Simon L, Spinella JF, Yao CY, Lavallée VP, Boivin I, Boucher G, Audemard E, Bordeleau ME, Lemieux S, Hebert J, Sauvageau G. High frequency of germline RUNX1 mutations in RUNX1 mutated AML patients. Blood. PMID 32315381 DOI: 10.1182/Blood.2019003357  1
2020 Dumont‐Lagacé M, Li Q, Tanguay M, Chagraoui J, Kientega T, Cardin GB, Brasey A, Trofimov A, Carli C, Ahmad I, Bambace N, Bernard L, Kiss TL, Roy J, Roy D, ... ... Sauvageau G, et al. Single UM171‐Expanded Cord Blood Transplants Support Robust T‐Cell Reconstitution with Low Rates of Severe Infections Stem Cells Translational Medicine. 9. DOI: 10.1002/Sctm.12813  1
2019 Kettyle LM, Lebert-Ghali CÉ, Grishagin IV, Dickson GJ, O'Reilly PG, Simpson DA, Bijl JJ, Mills KI, Sauvageau G, Thompson A. Pathways, Processes, and Candidate Drugs Associated with a Cluster-Dependency Model of Leukemia. Cancers. 11. PMID 31861091 DOI: 10.3390/Cancers11122036  1
2019 Cohen S, Roy J, Lachance S, Delisle JS, Marinier A, Busque L, Roy DC, Barabé F, Ahmad I, Bambace N, Bernard L, Kiss T, Bouchard P, Caudrelier P, Landais S, ... ... Sauvageau G, et al. Hematopoietic stem cell transplantation using single UM171-expanded cord blood: a single-arm, phase 1-2 safety and feasibility study. The Lancet. Haematology. PMID 31704264 DOI: 10.1016/S2352-3026(19)30202-9  1
2019 Chagraoui J, Lehnertz B, Girard S, Spinella JF, Fares I, Tomellini E, Mayotte N, Corneau S, MacRae T, Simon L, Sauvageau G. UM171 induces a homeostatic inflammatory-detoxification response supporting human HSC self-renewal. Plos One. 14: e0224900. PMID 31703090 DOI: 10.1371/Journal.Pone.0224900  1
2019 Lemieux C, Ahmad I, Bambace NM, Bernard L, Cohen S, Delisle JS, Fleury I, Kiss T, Mollica L, Roy DC, Sauvageau G, Roy J, Lachance S. Evaluation of the Impact of Autologous Hematopoietic Stem Cell Transplantation on the Quality of Life of Older Lymphoma Patients. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. PMID 31521818 DOI: 10.1016/J.Bbmt.2019.09.007  1
2019 Audemard EO, Gendron P, Feghaly A, Lavallée VP, Hébert J, Sauvageau G, Lemieux S. Targeted variant detection using unaligned RNA-Seq reads. Life Science Alliance. 2. PMID 31427380 DOI: 10.26508/lsa.201900336  1
2019 Tremblay G, Rousseau B, Marquis M, Beaubois C, Sauvageau G, Hébert J. Cost-Effectiveness Analysis of a HMGA2 Prognostic Test for Acute Myeloid Leukemia in a Canadian Setting. Applied Health Economics and Health Policy. PMID 31392669 DOI: 10.1007/S40258-019-00503-5  1
2019 Tomellini E, Fares I, Lehnertz B, Chagraoui J, Mayotte N, MacRae T, Bordeleau MÈ, Corneau S, Bisaillon R, Sauvageau G. Integrin-α3 Is a Functional Marker of Ex Vivo Expanded Human Long-Term Hematopoietic Stem Cells. Cell Reports. 28: 1063-1073.e5. PMID 31340144 DOI: 10.1016/J.Celrep.2019.06.084  1
2019 Bisaillon R, Moison C, Thiollier C, Krosl J, Bordeleau ME, Lehnertz B, Lavallée VP, MacRae T, Mayotte N, Labelle C, Boucher G, Spinella JF, Boivin I, D'Angelo G, Lavallée S, ... ... Sauvageau G, et al. Genetic characterization of ABT-199 sensitivity in human AML. Leukemia. PMID 31300747 DOI: 10.1038/S41375-019-0485-X  1
2019 Baccelli I, Gareau Y, Lehnertz B, Gingras S, Spinella JF, Corneau S, Mayotte N, Girard S, Frechette M, Blouin-Chagnon V, Leveillé K, Boivin I, MacRae T, Krosl J, Thiollier C, ... ... Sauvageau G, et al. Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia. Cancer Cell. 36: 84-99.e8. PMID 31287994 DOI: 10.1016/J.Ccell.2019.06.003  1
2019 Dubois EL, Guitton-Sert L, Béliveau M, Parmar K, Chagraoui J, Vignard J, Pauty J, Caron MC, Coulombe Y, Buisson R, Jacquet K, Gamblin C, Gao Y, Laprise P, Lebel M, ... Sauvageau G, et al. A Fanci knockout mouse model reveals common and distinct functions for FANCI and FANCD2. Nucleic Acids Research. PMID 31219578 DOI: 10.1093/Nar/Gkz514  1
2019 Angenendt L, Bormann E, Pabst C, Alla V, Görlich D, Braun L, Dohlich K, Schwöppe C, Bohlander SK, Arteaga MF, Wethmar K, Hartmann W, Angenendt A, Kessler T, Mesters RM, ... ... Sauvageau G, et al. The neuropeptide receptor calcitonin receptor-like (CALCRL) is a potential therapeutic target in acute myeloid leukemia. Leukemia. PMID 31182782 DOI: 10.1038/S41375-019-0505-X  1
2019 Roy DC, Lachance S, Cohen S, Delisle JS, Kiss T, Sauvageau G, Busque L, Ahmad I, Bernard L, Bambace N, Boumédine RS, Guertin MC, Rezvani K, Mielke S, Perreault C, et al. Allodepleted T-cell immunotherapy after haploidentical haematopoietic stem cell transplantation without severe acute graft-versus-host disease (GVHD) in the absence of GVHD prophylaxis. British Journal of Haematology. PMID 31135970 DOI: 10.1111/Bjh.15970  1
2019 Garg S, Reyes-Palomares A, He L, Bergeron A, Lavallée VP, Lemieux S, Gendron P, Rohde C, Xia J, Jagdhane P, Müller-Tidow C, Lipka DB, Imren S, Humphries RK, Waskow C, ... ... Sauvageau G, et al. Hepatic leukemia factor is a novel leukemic stem cell regulator in DNMT3A, NPM1, and FLT3-ITD triple-mutated AML. Blood. PMID 31076446 DOI: 10.1182/Blood.2018862383  1
2019 Marquis M, Beaubois C, Lavallée VP, Abrahamowicz M, Danieli C, Lemieux S, Ahmad I, Wei A, Ting SB, Fleming S, Schwarer A, Grimwade D, Grey W, Hills RK, Vyas P, ... ... Sauvageau G, et al. Correction: High expression of HMGA2 independently predicts poor clinical outcomes in acute myeloid leukemia. Blood Cancer Journal. 9: 28. PMID 30820024 DOI: 10.1038/S41408-019-0190-Z  1
2019 Moison C, Lavallée VP, Thiollier C, Lehnertz B, Boivin I, Mayotte N, Gareau Y, Fréchette M, Blouin-Chagnon V, Corneau S, Lavallée S, Lemieux S, Marinier A, Hébert J, Sauvageau G. Complex karyotype AML displays G2/M signature and hypersensitivity to PLK1 inhibition. Blood Advances. 3: 552-563. PMID 30782614 DOI: 10.1182/Bloodadvances.2018028480  1
2019 Lemieux C, Ahmad I, Bambace NM, Bernard L, Cohen S, Delisle JS, Fleury I, Kiss T, Mollica L, Roy DC, Sauvageau G, Roy J, Lachance S. Outcome of autologous hematopoietic stem cell transplant in older patients with B cell lymphoma when selected for fitness and chemosensitive disease. Leukemia Research. PMID 30654975 DOI: 10.1016/J.Leukres.2019.01.002  1
2018 Ngom M, Imren S, Maetzig T, Adair JE, Knapp DJHF, Chagraoui J, Fares I, Bordeleau ME, Sauvageau G, Leboulch P, Eaves C, Humphries RK. UM171 Enhances Lentiviral Gene Transfer and Recovery of Primitive Human Hematopoietic Cells. Molecular Therapy. Methods & Clinical Development. 10: 156-164. PMID 30101153 DOI: 10.1016/J.Omtm.2018.06.009  1
2018 Marquis M, Beaubois C, Lavallée VP, Abrahamowicz M, Danieli C, Lemieux S, Ahmad I, Wei A, Ting SB, Fleming S, Schwarer A, Grimwade D, Grey W, Hills RK, Vyas P, ... ... Sauvageau G, et al. High expression of HMGA2 independently predicts poor clinical outcomes in acute myeloid leukemia. Blood Cancer Journal. 8: 68. PMID 30061630 DOI: 10.1038/S41408-018-0103-6  1
2018 Lavallée VP, Chagraoui J, MacRae T, Marquis M, Bonnefoy A, Krosl J, Lemieux S, Marinier A, Pabst C, Rivard GÉ, Hébert J, Sauvageau G. Transcriptomic landscape of acute promyelocytic leukemia reveals aberrant surface expression of the platelet aggregation agonist Podoplanin. Leukemia. PMID 29550835 DOI: 10.1038/S41375-018-0069-1  1
2017 Simon L, Lavallée VP, Bordeleau ME, Krosl J, Baccelli I, Boucher G, Lehnertz B, Chagraoui J, MacRae T, Ruel R, Chantigny YA, Lemieux S, Marinier A, Hébert J, Sauvageau G. Chemogenomic landscape of RUNX1-mutated AML reveals importance of RUNX1 allele dosage in genetics and glucocorticoid sensitivity. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28855357 DOI: 10.1158/1078-0432.Ccr-17-1259  1
2017 Lehnertz B, Zhang YW, Boivin I, Mayotte N, Tomellini E, Chagraoui J, Lavallée VP, Hébert J, Sauvageau G. H3(K27M/I) mutations promote context-dependent transformation in acute myeloid leukemia with RUNX1 alterations. Blood. PMID 28855157 DOI: 10.1182/Blood-2017-03-774653  1
2017 Aucagne R, Girard S, Mayotte N, Lehnertz B, Lopes-Paciencia S, Gendron P, Boucher G, Chagraoui J, Sauvageau G. UBAP2L is amplified in a large subset of human lung adenocarcinoma and is critical for epithelial lung cell identity and tumor metastasis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28754713 DOI: 10.1096/Fj.201601219Rrr  1
2017 Zhou F, Liu Y, Rohde C, Pauli C, Gerloff D, Köhn M, Misiak D, Bäumer N, Cui C, Göllner S, Oellerich T, Serve H, Garcia-Cuellar MP, Slany R, Maciejewski JP, ... ... Sauvageau G, et al. AML1-ETO requires enhanced C/D box snoRNA/RNP formation to induce self-renewal and leukaemia. Nature Cell Biology. PMID 28650479 DOI: 10.1038/Ncb3563  1
2017 Lemieux S, Sargeant T, Laperrière D, Ismail H, Boucher G, Rozendaal M, Lavallée VP, Ashton-Beaucage D, Wilhelm B, Hébert J, Hilton DJ, Mader S, Sauvageau G. MiSTIC, an integrated platform for the analysis of heterogeneity in large tumour transcriptome datasets. Nucleic Acids Research. PMID 28472340 DOI: 10.1093/Nar/Gkx338  1
2017 Fares I, Chagraoui J, Lehnertz B, MacRae T, Mayotte N, Tomellini E, Aubert L, Roux PP, Sauvageau G. EPCR expression marks UM171-expanded CD34(+) cord blood stem cells. Blood. PMID 28408459 DOI: 10.1182/Blood-2016-11-750729  1
2017 Priam P, Krasteva V, Rousseau P, D'Angelo G, Gaboury L, Sauvageau G, Lessard JA. SMARCD2 subunit of SWI/SNF chromatin-remodeling complexes mediates granulopoiesis through a CEBPɛ dependent mechanism. Nature Genetics. PMID 28369034 DOI: 10.1038/Ng.3812  1
2017 Richard-Carpentier G, Sauvageau G. Bringing a Leukemic Stem Cell Gene Signature into Clinics: Are We There Yet? Cell Stem Cell. 20: 300-301. PMID 28257710 DOI: 10.1016/J.Stem.2017.02.010  0.01
2017 Boisjoly J, Bouchard P, Cohen S, Ahmad I, Bambace NM, Bernard L, Delisle J, Kiss TL, Roy D, Sauvageau G, Roy J, Lachance S. Impact of Carmustine (BCNU) Substitution for Bendamustine in the Conditioning Regimen Prior to Autologous Hematopoietic Cell Transplantation for the Treatment of Lymphoma Blood. 130: 2022-2022. DOI: 10.1182/Blood.V130.Suppl_1.2022.2022  1
2017 Lavallee V, Chagraoui J, Tara M, Marquis M, Arnaud B, Krosl J, Lemieux S, Rivard G, Hébert J, Sauvageau G. Podoplanin Expression in the Bleeding Complications of Acute Promyelocytic Leukemias Blood. 130: 105-105. DOI: 10.1182/Blood.V130.Suppl_1.105.105  1
2017 Simon L, Lavallée V, Bordeleau M, Krosl J, Baccelli I, Boucher G, Lehnertz B, MacRae T, Ruel R, Lemieux S, Marinier A, Hébert J, Sauvageau G. Abstract 1509: RUNX1 dosage dictates gene signature andin vitroresponse to glucocorticoids in acute myeloid leukemia Cancer Research. 77: 1509-1509. DOI: 10.1158/1538-7445.Am2017-1509  1
2016 Baril C, Gavory G, Bidla G, Knævelsrud H, Sauvageau G, Therrien M. Human NUP98-HOXA9 promotes hyperplastic growth of hematopoietic tissues in Drosophila. Developmental Biology. PMID 27838340 DOI: 10.1016/J.Ydbio.2016.11.003  0.01
2016 Knapp DJ, Hammond CA, Aghaeepour N, Miller PH, Pellacani D, Beer PA, Sachs K, Qiao W, Wang W, Humphries RK, Sauvageau G, Zandstra PW, Bendall SC, Nolan GP, Hansen C, et al. Distinct signaling programs control human hematopoietic stem cell survival and proliferation. Blood. PMID 27827829 DOI: 10.1182/Blood-2016-09-740654  1
2016 Gerby B, Veiga DF, Krosl J, Nourreddine S, Ouellette J, Haman A, Lavoie G, Fares I, Tremblay M, Litalien V, Ottoni E, Kosic M, Geoffrion D, Ryan J, Maddox PS, ... ... Sauvageau G, et al. High-throughput screening in niche-based assay identifies compounds to target preleukemic stem cells. The Journal of Clinical Investigation. PMID 27797342 DOI: 10.1172/Jci86489  1
2016 Rouette A, Trofimov A, Haberl D, Boucher G, Lavallée VP, D'Angelo G, Hébert J, Sauvageau G, Lemieux S, Perreault C. Expression of immunoproteasome genes is regulated by cell-intrinsic and -extrinsic factors in human cancers. Scientific Reports. 6: 34019. PMID 27659694 DOI: 10.1038/Srep34019  1
2016 Lavallée VP, Krosl J, Lemieux S, Boucher G, Gendron P, Pabst C, Boivin I, Marinier A, Guidos CJ, Meloche S, Hébert J, Sauvageau G. Chemo-genomic interrogation of CEBPA mutated AML reveals recurrent CSF3R mutations and subgroup sensitivity to JAK inhibitors. Blood. PMID 27034432 DOI: 10.1182/Blood-2016-03-705053  1
2016 Lavallée VP, Lemieux S, Boucher G, Gendron P, Boivin I, Armstrong RN, Sauvageau G, Hébert J. RNA-sequencing analysis of core binding factor AML identifies recurrent ZBTB7A mutations and defines RUNX1-CBFA2T3 fusion signature. Blood. PMID 26968532 DOI: 10.1182/Blood-2016-03-703868  1
2016 Pabst C, Bergeron A, Lavallée VP, Yeh J, Gendron P, Norddahl GL, Krosl J, Boivin I, Deneault E, Simard J, Imren S, Boucher G, Eppert K, Herold T, Bohlander SK, ... ... Sauvageau G, et al. GPR56 identifies primary human acute myeloid leukemia cells with high repopulating potential in vivo. Blood. PMID 26834243 DOI: 10.1182/Blood-2015-11-683649  1
2016 Lavallée VP, Lemieux S, Boucher G, Gendron P, Boivin I, Girard S, Hébert J, Sauvageau G. Identification of MYC mutations in acute myeloid leukemias with NUP98-NSD1 translocations Leukemia. 30: 1621-1624. DOI: 10.1038/leu.2016.19  1
2016 Maiga A, Lemieux S, Pabst C, Lavallée VP, Bouvier M, Sauvageau G, Hébert J. Transcriptome analysis of G protein-coupled receptors in distinct genetic subgroups of acute myeloid leukemia: Identification of potential disease-specific targets Blood Cancer Journal. 6. DOI: 10.1038/bcj.2016.36  1
2015 Ahmad I, LeBlanc R, Cohen S, Lachance S, Kiss T, Sauvageau G, Roy DC, Busque L, Delisle JS, Bambace N, Bernard L, Sabry W, Roy J. Favorable long-term outcome of patients with multiple myeloma using a frontline tandem approach with autologous and non-myeloablative allogeneic transplantation. Bone Marrow Transplantation. PMID 26691426 DOI: 10.1038/bmt.2015.319  1
2015 Lebert-Ghali CÉ, Fournier M, Kettyle L, Thompson A, Sauvageau G, Bijl JJ. Hoxa cluster genes determine the proliferative activity of adult mouse hematopoietic stem and progenitor cells. Blood. PMID 26585953 DOI: 10.1182/Blood-2015-02-626390  1
2015 Lavallée VP, Baccelli I, Krosl J, Wilhelm B, Barabé F, Gendron P, Boucher G, Lemieux S, Marinier A, Meloche S, Hébert J, Sauvageau G. The transcriptomic landscape and directed chemical interrogation of MLL-rearranged acute myeloid leukemias. Nature Genetics. 47: 1030-7. PMID 26237430 DOI: 10.1038/Ng.3371  1
2015 Fares I, Rivest-Khan L, Cohen S, Sauvageau G. Small molecule regulation of normal and leukemic stem cells. Current Opinion in Hematology. 22: 309-16. PMID 26049751 DOI: 10.1097/Moh.0000000000000151  1
2015 Grote D, Moison C, Duhamel S, Chagraoui J, Girard S, Yang J, Mayotte N, Coulombe Y, Masson JY, Brown GW, Meloche S, Sauvageau G. E4F1 is a master regulator of CHK1-mediated functions. Cell Reports. 11: 210-9. PMID 25843717 DOI: 10.1016/J.Celrep.2015.03.019  1
2015 Fortier S, MacRae T, Bilodeau M, Sargeant T, Sauvageau G. Haploinsufficiency screen highlights two distinct groups of ribosomal protein genes essential for embryonic stem cell fate. Proceedings of the National Academy of Sciences of the United States of America. 112: 2127-32. PMID 25646475 DOI: 10.1073/Pnas.1418845112  1
2015 Lavallée VP, Gendron P, Lemieux S, D'Angelo G, Hébert J, Sauvageau G. EVI1-rearranged acute myeloid leukemias are characterized by distinct molecular alterations. Blood. 125: 140-3. PMID 25331116 DOI: 10.1182/Blood-2014-07-591529  1
2015 Sauvageau G, Frayret JM. Waste paper procurement optimization: An agent-based simulation approach European Journal of Operational Research. 242: 987-998. DOI: 10.1016/J.Ejor.2014.10.035  1
2014 Gerby B, Tremblay CS, Tremblay M, Rojas-Sutterlin S, Herblot S, Hébert J, Sauvageau G, Lemieux S, Lécuyer E, Veiga DF, Hoang T. SCL, LMO1 and Notch1 reprogram thymocytes into self-renewing cells. Plos Genetics. 10: e1004768. PMID 25522233 DOI: 10.1371/Journal.Pgen.1004768  1
2014 Kleiderman E, Avard D, Besso A, Ali-Khan S, Sauvageau G, Hébert J. Disclosure of incidental findings in cancer genomic research: investigators' perceptions on obligations and barriers. Clinical Genetics. PMID 25492269 DOI: 10.1111/Cge.12540  1
2014 Fares I, Chagraoui J, Gareau Y, Gingras S, Ruel R, Mayotte N, Csaszar E, Knapp DJ, Miller P, Ngom M, Imren S, Roy DC, Watts KL, Kiem HP, Herrington R, ... ... Sauvageau G, et al. Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal. Science (New York, N.Y.). 345: 1509-12. PMID 25237102 DOI: 10.1126/Science.1256337  1
2014 Bordeleau ME, Aucagne R, Chagraoui J, Girard S, Mayotte N, Bonneil E, Thibault P, Pabst C, Bergeron A, Barabé F, Hébert J, Sauvageau M, Boutonnet C, Meloche S, Sauvageau G. UBAP2L is a novel BMI1-interacting protein essential for hematopoietic stem cell activity. Blood. 124: 2362-9. PMID 25185265 DOI: 10.1182/Blood-2014-01-548651  1
2014 Pabst C, Krosl J, Fares I, Boucher G, Ruel R, Marinier A, Lemieux S, Hébert J, Sauvageau G. Identification of small molecules that support human leukemia stem cell activity ex vivo. Nature Methods. 11: 436-42. PMID 24562423 DOI: 10.1038/Nmeth.2847  1
2014 Lehnertz B, Pabst C, Su L, Miller M, Liu F, Yi L, Zhang R, Krosl J, Yung E, Kirschner J, Rosten P, Underhill TM, Jin J, Hébert J, Sauvageau G, et al. The methyltransferase G9a regulates HoxA9-dependent transcription in AML. Genes & Development. 28: 317-27. PMID 24532712 DOI: 10.1101/Gad.236794.113  1
2014 Celton M, Forest A, Gosse G, Lemieux S, Hebert J, Sauvageau G, Wilhelm BT. Epigenetic regulation of GATA2 and its impact on normal karyotype acute myeloid leukemia. Leukemia. 28: 1617-26. PMID 24514424 DOI: 10.1038/Leu.2014.67  1
2014 Buscarlet M, Krasteva V, Ho L, Simon C, Hébert J, Wilhelm B, Crabtree GR, Sauvageau G, Thibault P, Lessard JA. Essential role of BRG, the ATPase subunit of BAF chromatin remodeling complexes, in leukemia maintenance. Blood. 123: 1720-8. PMID 24478402 DOI: 10.1182/Blood-2013-02-483495  1
2013 Macrae T, Sargeant T, Lemieux S, Hébert J, Deneault E, Sauvageau G. RNA-Seq reveals spliceosome and proteasome genes as most consistent transcripts in human cancer cells. Plos One. 8: e72884. PMID 24069164 DOI: 10.1371/Journal.Pone.0072884  1
2013 Cellot S, Hope KJ, Chagraoui J, Sauvageau M, Deneault É, MacRae T, Mayotte N, Wilhelm BT, Landry JR, Ting SB, Krosl J, Humphries K, Thompson A, Sauvageau G. RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity. Blood. 122: 1545-55. PMID 23777767 DOI: 10.1182/Blood-2013-04-496281  1
2013 Black L, Avard D, Zawati MH, Knoppers BM, Hébert J, Sauvageau G. Funding considerations for the disclosure of genetic incidental findings in biobank research. Clinical Genetics. 84: 397-406. PMID 23662709 DOI: 10.1111/Cge.12190  1
2013 Ramsey JM, Kettyle LM, Sharpe DJ, Mulgrew NM, Dickson GJ, Bijl JJ, Austin P, Mayotte N, Cellot S, Lappin TR, Zhang SD, Mills KI, Krosl J, Sauvageau G, Thompson A. Entinostat prevents leukemia maintenance in a collaborating oncogene-dependent model of cytogenetically normal acute myeloid leukemia. Stem Cells (Dayton, Ohio). 31: 1434-45. PMID 23592435 DOI: 10.1002/Stem.1398  1
2013 Deneault E, Wilhelm BT, Bergeron A, Barabé F, Sauvageau G. Identification of non-cell-autonomous networks from engineered feeder cells that enhance murine hematopoietic stem cell activity. Experimental Hematology. 41: 470-478.e4. PMID 23340137 DOI: 10.1016/J.Exphem.2013.01.003  1
2013 Holbro A, Ahmad I, Cohen S, Roy J, Lachance S, Chagnon M, LeBlanc R, Bernard L, Busque L, Roy DC, Sauvageau G, Kiss TL. Safety and cost-effectiveness of outpatient autologous stem cell transplantation in patients with multiple myeloma. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 19: 547-51. PMID 23253556 DOI: 10.1016/J.Bbmt.2012.12.006  1
2012 Trost M, Sauvageau M, Hérault O, Deleris P, Pomiès C, Chagraoui J, Mayotte N, Meloche S, Sauvageau G, Thibault P. Posttranslational regulation of self-renewal capacity: insights from proteome and phosphoproteome analyses of stem cell leukemia. Blood. 120: e17-27. PMID 22802335 DOI: 10.1182/Blood-2011-12-397844  1
2012 Herault O, Hope KJ, Deneault E, Mayotte N, Chagraoui J, Wilhelm BT, Cellot S, Sauvageau M, Andrade-Navarro MA, Hébert J, Sauvageau G. A role for GPx3 in activity of normal and leukemia stem cells. The Journal of Experimental Medicine. 209: 895-901. PMID 22508837 DOI: 10.1084/Jem.20102386  1
2012 Simon C, Chagraoui J, Krosl J, Gendron P, Wilhelm B, Lemieux S, Boucher G, Chagnon P, Drouin S, Lambert R, Rondeau C, Bilodeau A, Lavallée S, Sauvageau M, Hébert J, ... Sauvageau G, et al. A key role for EZH2 and associated genes in mouse and human adult T-cell acute leukemia. Genes & Development. 26: 651-6. PMID 22431509 DOI: 10.1101/Gad.186411.111  1
2012 Ting SB, Deneault E, Hope K, Cellot S, Chagraoui J, Mayotte N, Dorn JF, Laverdure JP, Harvey M, Hawkins ED, Russell SM, Maddox PS, Iscove NN, Sauvageau G. Asymmetric segregation and self-renewal of hematopoietic stem and progenitor cells with endocytic Ap2a2. Blood. 119: 2510-22. PMID 22174158 DOI: 10.1182/Blood-2011-11-393272  1
2012 Cohen S, Kiss T, Lachance S, Roy DC, Sauvageau G, Busque L, Ahmad I, Roy J. Tandem autologous-allogeneic nonmyeloablative sibling transplantation in relapsed follicular lymphoma leads to impressive progression-free survival with minimal toxicity. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 18: 951-7. PMID 22155507 DOI: 10.1182/Blood.V114.22.50.50  1
2012 Holbro A, Ahmad I, Busque L, Cohen S, Lachance S, Roy DC, Roy J, Sauvageau G, Kiss T. Cardiac tamponade potentially related to sirolimus following cord blood transplantation. Bone Marrow Transplantation. 47: 294-5. PMID 21399672 DOI: 10.1038/Bmt.2011.44  1
2011 Bisaillon R, Wilhelm BT, Krosl J, Sauvageau G. C-terminal domain of MEIS1 converts PKNOX1 (PREP1) into a HOXA9-collaborating oncoprotein. Blood. 118: 4682-9. PMID 21900201 DOI: 10.1182/Blood-2011-05-354076  1
2011 Ahmad I, Labbé AC, Chagnon M, Busque L, Cohen S, Kiss T, Lachance S, Roy DC, Sauvageau G, Roy J. Incidence and prognostic value of eosinophilia in chronic graft-versus-host disease after nonmyeloablative hematopoietic cell transplantation. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 17: 1673-8. PMID 21601640 DOI: 10.1016/J.Bbmt.2011.04.012  1
2011 Hope KJ, Sauvageau G. Roles for MSI2 and PROX1 in hematopoietic stem cell activity. Current Opinion in Hematology. 18: 203-7. PMID 21577104 DOI: 10.1097/Moh.0B013E328347888A  1
2011 Chagraoui J, Hébert J, Girard S, Sauvageau G. An anticlastogenic function for the Polycomb Group gene Bmi1. Proceedings of the National Academy of Sciences of the United States of America. 108: 5284-9. PMID 21402923 DOI: 10.1073/Pnas.1014263108  1
2011 Volpato JP, Mayotte N, Fossati E, Guerrero V, Sauvageau G, Pelletier JN. Selectively weakened binding of methotrexate by human dihydrofolate reductase allows rapid ex vivo selection of mammalian cells Journal of Molecular Recognition. 24: 188-198. PMID 21360609 DOI: 10.1002/Jmr.1037  1
2011 Wilhelm BT, Briau M, Austin P, Faubert A, Boucher G, Chagnon P, Hope K, Girard S, Mayotte N, Landry JR, Hébert J, Sauvageau G. RNA-seq analysis of 2 closely related leukemia clones that differ in their self-renewal capacity. Blood. 117: e27-38. PMID 20980679 DOI: 10.1182/Blood-2010-07-293332  1
2010 Fortier S, Bilodeau M, Macrae T, Laverdure JP, Azcoitia V, Girard S, Chagraoui J, Ringuette N, Hébert J, Krosl J, Mayotte N, Sauvageau G. Genome-wide interrogation of Mammalian stem cell fate determinants by nested chromosome deletions. Plos Genetics. 6: e1001241. PMID 21170304 DOI: 10.1371/Journal.Pgen.1001241  1
2010 Sauvageau G, Humphries RK. Medicine. The blood stem cell Holy Grail? Science (New York, N.Y.). 329: 1291-2. PMID 20829472 DOI: 10.1126/Science.1195173  1
2010 Sauvageau M, Sauvageau G. Polycomb group proteins: multi-faceted regulators of somatic stem cells and cancer. Cell Stem Cell. 7: 299-313. PMID 20804967 DOI: 10.1016/J.Stem.2010.08.002  1
2010 Lebert-Ghali CE, Fournier M, Dickson GJ, Thompson A, Sauvageau G, Bijl JJ. HoxA cluster is haploinsufficient for activity of hematopoietic stem and progenitor cells. Experimental Hematology. 38: 1074-1086.e1-5. PMID 20655978 DOI: 10.1016/J.Exphem.2010.07.006  1
2010 Hope KJ, Cellot S, Ting SB, MacRae T, Mayotte N, Iscove NN, Sauvageau G. An RNAi screen identifies Msi2 and Prox1 as having opposite roles in the regulation of hematopoietic stem cell activity. Cell Stem Cell. 7: 101-13. PMID 20621054 DOI: 10.1016/J.Stem.2010.06.007  1
2010 Krosl J, Mamo A, Chagraoui J, Wilhelm BT, Girard S, Louis I, Lessard J, Perreault C, Sauvageau G. A mutant allele of the Swi/Snf member BAF250a determines the pool size of fetal liver hemopoietic stem cell populations. Blood. 116: 1678-84. PMID 20522713 DOI: 10.1182/Blood-2010-03-273862  1
2010 Lacombe J, Herblot S, Rojas-Sutterlin S, Haman A, Barakat S, Iscove NN, Sauvageau G, Hoang T. Scl regulates the quiescence and the long-term competence of hematopoietic stem cells. Blood. 115: 792-803. PMID 19850742 DOI: 10.1182/Blood-2009-01-201384  1
2010 Detrait M, Meunier C, Roy DC, Kiss T, Lachance S, Cohen S, Busque L, Sauvageau G, Roy J. Late acute renal failure due to bilateral kidney infiltration by ALL as single manifestation of relapse after allogeneic transplantation. Bone Marrow Transplantation. 45: 953-4. PMID 19767785 DOI: 10.1038/bmt.2009.246  1
2010 Detrait M, Boivin G, Delage R, Béliveau C, Labbé A, Cohen S, Kiss T, Busque L, Roy D, Sauvageau G, Roy J. High dose valacyclovir is highly effective to prevent cytomegalovirus and other herpes viruses viremia F1000research. 1. DOI: 10.7490/F1000Research.182.1  1
2009 Bilodeau M, MacRae T, Gaboury L, Laverdure JP, Hardy MP, Mayotte N, Paradis V, Harton S, Perreault C, Sauvageau G. Analysis of blood stem cell activity and cystatin gene expression in a mouse model presenting a chromosomal deletion encompassing Csta and Stfa2l1. Plos One. 4: e7500. PMID 19838297 DOI: 10.1371/Journal.Pone.0007500  1
2009 Sabry W, Le Blanc R, Labbé AC, Sauvageau G, Couban S, Kiss T, Busque L, Cohen S, Lachance S, Roy DC, Roy J. Graft-versus-host disease prophylaxis with tacrolimus and mycophenolate mofetil in HLA-matched nonmyeloablative transplant recipients is associated with very low incidence of GVHD and nonrelapse mortality. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 15: 919-29. PMID 19589481 DOI: 10.1016/J.Bbmt.2009.04.004  1
2009 Deneault E, Cellot S, Faubert A, Laverdure JP, Fréchette M, Chagraoui J, Mayotte N, Sauvageau M, Ting SB, Sauvageau G. A functional screen to identify novel effectors of hematopoietic stem cell activity. Cell. 137: 369-79. PMID 19379700 DOI: 10.1016/J.Cell.2009.03.026  1
2009 Csaszar E, Gavigan G, Ungrin M, Thérien C, Dubé P, Féthière J, Sauvageau G, Roy DC, Zandstra PW. An automated system for delivery of an unstable transcription factor to hematopoietic stem cell cultures. Biotechnology and Bioengineering. 103: 402-12. PMID 19266473 DOI: 10.1002/Bit.22297  1
2009 Detrait M, Poirier L, Roy DC, Kiss T, Busque L, Cohen S, Lachance S, Sauvageau G, Roy J. Diphyllobothriasis, a rare cause of profuse diarrhea following autologous transplantation. Bone Marrow Transplantation. 44: 131-2. PMID 19169286 DOI: 10.1038/bmt.2008.439  1
2008 Sauvageau G, Perreault C. Killer granzyme B linked to N-myc- and c-myc-dependent HSC survival: isn't that comyc? Cell Stem Cell. 3: 579-80. PMID 19041771 DOI: 10.1016/J.Stem.2008.11.003  1
2008 Faubert A, Chagraoui J, Mayotte N, Fréchette M, Iscove NN, Humphries RK, Sauvageau G. Complementary and independent function for Hoxb4 and Bmi1 in HSC activity. Cold Spring Harbor Symposia On Quantitative Biology. 73: 555-64. PMID 19022763 DOI: 10.1101/sqb.2008.73.030  1
2008 Bijl J, Krosl J, Lebert-Ghali CE, Vacher J, Mayotte N, Sauvageau G. Evidence for Hox and E2A-PBX1 collaboration in mouse T-cell leukemia Oncogene. 27: 6356-6364. PMID 18679416 DOI: 10.1038/onc.2008.233  1
2008 Louis I, Heinonen KM, Chagraoui J, Vainio S, Sauvageau G, Perreault C. The signaling protein Wnt4 enhances thymopoiesis and expands multipotent hematopoietic progenitors through beta-catenin-independent signaling. Immunity. 29: 57-67. PMID 18617424 DOI: 10.1016/J.Immuni.2008.04.023  1
2008 Sauvageau M, Sauvageau G. Polycomb group genes: keeping stem cell activity in balance. Plos Biology. 6: e113. PMID 18447587 DOI: 10.1371/Journal.Pbio.0060113  1
2008 Sauvageau M, Miller M, Lemieux S, Lessard J, Hébert J, Sauvageau G. Quantitative expression profiling guided by common retroviral insertion sites reveals novel and cell type specific cancer genes in leukemia. Blood. 111: 790-9. PMID 17906077 DOI: 10.1182/Blood-2007-07-098236  1
2008 Chagraoui J, Hebert J, Girard S, Sauvageau G. BMI1 Interacts with FANCD2 at DNA Lesions and Prevents Chromosome Breaks Blood. 112: 3099-3099. DOI: 10.1182/Blood.V112.11.3099.3099  1
2007 Labbé AC, Su SH, Laverdière M, Pépin J, Patiño C, Cohen S, Kiss T, Lachance S, Sauvageau G, Busque L, Roy DC, Roy J. High incidence of invasive aspergillosis associated with intestinal graft-versus-host disease following nonmyeloablative transplantation. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 13: 1192-200. PMID 17889356 DOI: 10.1016/J.Bbmt.2007.06.013  1
2007 Ohta H, Sekulovic S, Bakovic S, Eaves CJ, Pineault N, Gasparetto M, Smith C, Sauvageau G, Humphries RK. Near-maximal expansions of hematopoietic stem cells in culture using NUP98-HOX fusions. Experimental Hematology. 35: 817-30. PMID 17577930 DOI: 10.1016/J.Exphem.2007.02.012  1
2007 Cellot S, Krosl J, Chagraoui J, Meloche S, Humphries RK, Sauvageau G. Sustained in vitro trigger of self-renewal divisions in Hoxb4hiPbx1(10) hematopoietic stem cells. Experimental Hematology. 35: 802-16. PMID 17577929 DOI: 10.1016/J.Exphem.2007.02.013  1
2007 Cellot S, Sauvageau G. Zfx: at the crossroads of survival and self-renewal. Cell. 129: 239-41. PMID 17448983 DOI: 10.1016/J.Cell.2007.04.002  1
2007 Bilodeau M, Girard S, Hébert J, Sauvageau G. A retroviral strategy that efficiently creates chromosomal deletions in mammalian cells. Nature Methods. 4: 263-8. PMID 17277782 DOI: 10.1038/Nmeth1011  1
2006 Bilodeau M, Sauvageau G. Uncovering stemness. Nature Cell Biology. 8: 1048-9. PMID 17013416 DOI: 10.1038/ncb1006-1048  1
2006 Chagraoui J, Niessen SL, Lessard J, Girard S, Coulombe P, Sauvageau M, Meloche S, Sauvageau G. E4F1: a novel candidate factor for mediating BMI1 function in primitive hematopoietic cells. Genes & Development. 20: 2110-20. PMID 16882984 DOI: 10.1101/Gad.1453406  1
2006 Cellot S, Sauvageau G. In vitro stem cell expansion: stepping closer towards self-renewal. Gene Therapy. 13: 1617-8. PMID 16738689 DOI: 10.1038/sj.gt.3302804  1
2006 Mamo A, Krosl J, Kroon E, Bijl J, Thompson A, Mayotte N, Girard S, Bisaillon R, Beslu N, Featherstone M, Sauvageau G. Molecular dissection of Meis1 reveals 2 domains required for leukemia induction and a key role for Hoxa gene activation. Blood. 108: 622-9. PMID 16469876 DOI: 10.1182/Blood-2005-06-2244  1
2006 Dhédin N, Chamakhi I, Perreault C, Roy DC, Sauvageau G, Ducruet T, Busque L, Fish D, Bélanger R, Roy J. Evidence that donor intrinsic response to G-CSF is the best predictor of acute graft-vs-host disease following allogeneic peripheral blood stem cell transplantation. Experimental Hematology. 34: 107-14. PMID 16413397 DOI: 10.1016/J.Exphem.2005.09.013  1
2006 Bijl J, Thompson A, Ramirez-Solis R, Krosl J, Grier DG, Lawrence HJ, Sauvageau G. Analysis of HSC activity and compensatory Hox gene expression profile in Hoxb cluster mutant fetal liver cells. Blood. 108: 116-22. PMID 16339407 DOI: 10.1182/Blood-2005-06-2245  1
2005 Lawrence HJ, Christensen J, Fong S, Hu YL, Weissman I, Sauvageau G, Humphries RK, Largman C. Loss of expression of the Hoxa-9 homeobox gene impairs the proliferation and repopulating ability of hematopoietic stem cells. Blood. 106: 3988-94. PMID 16091451 DOI: 10.1182/Blood-2005-05-2003  1
2005 Martin NL, Saba-El-Leil MK, Sadekova S, Meloche S, Sauvageau G. EN2 is a candidate oncogene in human breast cancer. Oncogene. 24: 6890-901. PMID 16007149 DOI: 10.1038/Sj.Onc.1208840  1
2005 Cellot S, Sauvageau G. Gfi-1: another piece in the HSC puzzle. Trends in Immunology. 26: 68-71. PMID 15668120 DOI: 10.1016/J.It.2004.12.005  1
2005 Bijl J, Sauvageau M, Thompson A, Sauvageau G. High incidence of proviral integrations in the Hoxa locus in a new model of E2a-PBX1-induced B-cell leukemia. Genes & Development. 19: 224-33. PMID 15655112 DOI: 10.1101/Gad.1268505  1
2005 Iwasaki M, Kuwata T, Yamazaki Y, Jenkins NA, Copeland NG, Osato M, Ito Y, Kroon E, Sauvageau G, Nakamura T. Identification of cooperative genes for NUP98-HOXA9 in myeloid leukemogenesis using a mouse model. Blood. 105: 784-93. PMID 15454493 DOI: 10.1182/Blood-2004-04-1508  1
2004 Faubert A, Lessard J, Sauvageau G. Are genetic determinants of asymmetric stem cell division active in hematopoietic stem cells? Oncogene. 23: 7247-55. PMID 15378084 DOI: 10.1038/Sj.Onc.1207944  1
2004 Sauvageau G, Iscove NN, Humphries RK. In vitro and in vivo expansion of hematopoietic stem cells. Oncogene. 23: 7223-32. PMID 15378082 DOI: 10.1038/Sj.Onc.1207942  1
2004 Lessard J, Faubert A, Sauvageau G. Genetic programs regulating HSC specification, maintenance and expansion. Oncogene. 23: 7199-209. PMID 15378080 DOI: 10.1038/Sj.Onc.1207940  1
2004 Beslu N, Krosl J, Laurin M, Mayotte N, Humphries KR, Sauvageau G. Molecular interactions involved in HOXB4-induced activation of HSC self-renewal. Blood. 104: 2307-14. PMID 15226173 DOI: 10.1182/Blood-2004-04-1653  1
2004 Krosl JK, Faubert A, Sauvageau G. Molecular basis for stem-cell self-renewal. The Hematology Journal : the Official Journal of the European Haematology Association / Eha. 5: S118-21. PMID 15190292 DOI: 10.1038/Sj.Thj.6200436  1
2003 Krosl J, Austin P, Beslu N, Kroon E, Humphries RK, Sauvageau G. In vitro expansion of hematopoietic stem cells by recombinant TAT-HOXB4 protein. Nature Medicine. 9: 1428-32. PMID 14578881 DOI: 10.1038/Nm951  1
2003 Lessard J, Sauvageau G. Polycomb group genes as epigenetic regulators of normal and leukemic hemopoiesis. Experimental Hematology. 31: 567-85. PMID 12842702 DOI: 10.1016/S0301-472X(03)00081-X  1
2003 Lessard J, Sauvageau G. Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells. Nature. 423: 255-60. PMID 12714970 DOI: 10.1038/Nature01572  1
2003 Krosl J, Beslu N, Mayotte N, Humphries RK, Sauvageau G. The competitive nature of HOXB4-transduced HSC is limited by PBX1: the generation of ultra-competitive stem cells retaining full differentiation potential. Immunity. 18: 561-71. PMID 12705858 DOI: 10.1016/S1074-7613(03)00090-6  1
2002 Mayotte N, Roy DC, Yao J, Kroon E, Sauvageau G. Oncogenic interaction between BCR-ABL and NUP98-HOXA9 demonstrated by the use of an in vitro purging culture system. Blood. 100: 4177-84. PMID 12393433 DOI: 10.1182/Blood-2002-04-1244  1
2002 Buske C, Feuring-Buske M, Abramovich C, Spiekermann K, Eaves CJ, Coulombel L, Sauvageau G, Hogge DE, Humphries RK. Deregulated expression of HOXB4 enhances the primitive growth activity of human hematopoietic cells. Blood. 100: 862-8. PMID 12130496 DOI: 10.1182/Blood-2002-01-0220  1
2002 Antonchuk J, Sauvageau G, Humphries RK. HOXB4-induced expansion of adult hematopoietic stem cells ex vivo. Cell. 109: 39-45. PMID 11955445 DOI: 10.1016/S0092-8674(02)00697-9  1
2002 Thorsteinsdottir U, Mamo A, Kroon E, Jerome L, Bijl J, Lawrence HJ, Humphries K, Sauvageau G. Overexpression of the myeloid leukemia-associated Hoxa9 gene in bone marrow cells induces stem cell expansion. Blood. 99: 121-9. PMID 11756161 DOI: 10.1182/Blood.V99.1.121  1
2001 Le Blanc R, Montminy-Métivier S, Bélanger R, Busque L, Fish D, Roy DC, Kassis J, Boileau J, Lavallée R, Bélanger D, Letendre F, Hébert J, Sauvageau G, Perreault C, Roy J. Allogeneic transplantation for multiple myeloma: further evidence for a GVHD-associated graft-versus-myeloma effect. Bone Marrow Transplantation. 28: 841-8. PMID 11781644 DOI: 10.1038/Sj.Bmt.1703253  1
2001 Antonchuk J, Sauvageau G, Humphries RK. HOXB4 overexpression mediates very rapid stem cell regeneration and competitive hematopoietic repopulation Experimental Hematology. 29: 1125-1134. PMID 11532354 DOI: 10.1016/S0301-472X(01)00681-6  1
2001 Kroon E, Thorsteinsdottir U, Mayotte N, Nakamura T, Sauvageau G. NUP98-HOXA9 expression in hemopoietic stem cells induces chronic and acute myeloid leukemias in mice Embo Journal. 20: 350-361. PMID 11157742 DOI: 10.1093/Emboj/20.3.350  1
2001 Thorsteinsdottir U, Kroon E, Jerome L, Blasi F, Sauvageau G. Defining roles for HOX and MEIS1 genes in induction of acute myeloid leukemia Molecular and Cellular Biology. 21: 224-234. PMID 11113197 DOI: 10.1128/Mcb.21.1.224-234.2001  1
2000 Krosl J, Sauvageau G. AP-1 complex is effector of Hox-induced cellular proliferation and transformation Oncogene. 19: 5134-5141. PMID 11064450 DOI: 10.1038/Sj.Onc.1203897  1
2000 Thorsteinsdottir U, Jerome L, Kroon E, Sauvageau G. Evidence for a mitotic clock in HSC which impairs hoxa9-induced leukemic transformation Blood. 96.  1
1999 Lessard J, Schumacher A, Thorsteinsdottir U, van Lohuizen M, Magnuson T, Sauvageau G. Functional antagonism of the Polycomb-Group genes eed and Bmi1 in hemopoietic cell proliferation. Genes & Development. 13: 2691-703. PMID 10541555 DOI: 10.1101/Gad.13.20.2691  1
1999 Thorsteinsdottir U, Sauvageau G, Humphries RK. Enhanced in vivo regenerative potential of HOXB4-transduced hematopoietic stem cells with regulation of their pool size Blood. 94: 2605-2612. PMID 10515864 DOI: 10.1182/Blood.V94.8.2605.420K19_2605_2612  1
1999 Thorsteinsdottir U, Krosl J, Kroon E, Haman A, Hoang T, Sauvageau G. The oncoprotein E2A-Pbx1a collaborates with Hoxa9 to acutely transform primary bone marrow cells Molecular and Cellular Biology. 19: 6355-6366. PMID 10454582 DOI: 10.1128/Mcb.19.9.6355  1
1998 Krosl J, Baban S, Krosl G, Rozenfeld S, Largman C, Sauvageau G. Cellular proliferation and transformation induced by HOXB4 and HOXB3 proteins involves cooperation with PBX1 Oncogene. 16: 3403-3412. PMID 9692548  1
1998 Kroon E, Krosl J, Thorsteinsdottir U, Baban S, Buchberg AM, Sauvageau G. Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b Embo Journal. 17: 3714-3725. PMID 9649441 DOI: 10.1093/Emboj/17.13.3714  1
1998 Lessard J, Baban S, Sauvageau G. Stage-specific expression of polycomb group genes in human bone marrow cells. Blood. 91: 1216-24. PMID 9454751 DOI: 10.1182/Blood.V91.4.1216  1
1998 Sauvageau G. Developmental genes and hemopo1etic stem cells Experimental Hematology. 26: 682.  1
1997 Thorsteinsdottir U, Sauvageau G, Humphries RK. Hox homeobox genes as regulators of normal and leukemic hematopoiesis Hematology/Oncology Clinics of North America. 11: 1221-1237. PMID 9443054 DOI: 10.1016/S0889-8588(05)70491-3  1
1997 Lawrence HJ, Helgason CD, Sauvageau G, Fong S, Izon DJ, Humphries RK, Largman C. Mice bearing a targeted interruption of the homeobox gene HOXA9 have defects in myeloid, erythroid, and lymphoid hematopoiesis Blood. 89: 1922-1930. PMID 9058712 DOI: 10.1182/Blood.V89.6.1922  1
1997 Sauvageau G, Thorsteinsdottir U, Hough MR, Hugo P, Lawrence HJ, Largman C, Humphries RK. Overexpression of HOXB3 in hematopoietic cells causes defective lymphoid development and progressive myeloproliferation Immunity. 6: 13-22. PMID 9052833 DOI: 10.1016/S1074-7613(00)80238-1  1
1997 Thorsteinsdottir U, Sauvageau G, Hough MR, Dragowska W, Lansdorp PM, Lawrence HJ, Largman C, Keith Humphries R. Overexpression of HOXA10 in murine hematopoietic cells perturbs both myeloid and lymphoid differentiation and leads to acute myeloid leukemia Molecular and Cellular Biology. 17: 495-505. PMID 8972230 DOI: 10.1128/Mcb.17.1.495  1
1997 Sauvageau G, Humphries RK. Expression and function of Hox genes in normal and leukemic hematopoiesis Hematologie. 3: 123-131.  1
1997 Lessard J, Baban S, Sauvageau G. Polycomb group genes are differentially expressed in hemopoietic subpopulations Experimental Hematology. 25: 794.  1
1996 Lawrence HJ, Sauvageau G, Humphries RK, Largman C. The role of HOX homeobox genes in normal and leukemic hematopoiesis Stem Cells. 14: 281-291. PMID 8724694 DOI: 10.1002/Stem.140281  1
1996 Helgason CD, Sauvageau G, Lawrence HJ, Largman C, Humphries RK. Overexpression of HOXB4 enhances the hematopoietic potential of embryonic stem cells differentiated in vitro Blood. 87: 2740-2749. PMID 8639890  1
1996 Shen WF, Chang CP, Rozenfeld S, Sauvageau G, Humphries RK, Lu M, Jeffrey Lawrence H, Cleary ML, Largman C. Hox homeodomain proteins exhibit selective complex stabilities with Pbx DNA Nucleic Acids Research. 24: 898-906. PMID 8600458  1
1996 Hough MR, Chappel MS, Sauvageau G, Takei F, Kay R, Humphries RK. Reduction of early B lymphocyte precursors in transgenic mice overexpressing the murine heat-stable antigen Journal of Immunology. 156: 479-488. PMID 8543797  1
1995 Sauvageau G, Thorsteinsdottir U, Eaves CJ, Lawrence HJ, Largman C, Lansdorp PM, Humphries RK. Overexpression of HOXB4 in hematopoietic cells causes the selective expansion of more primitive populations in vitro and in vivo Genes and Development. 9: 1753-1765. PMID 7622039 DOI: 10.1101/Gad.9.14.1753  1
1995 Lawrence HJ, Sauvageau G, Ahmadi N, Lopez AR, LeBeau MM, Link M, Humphries K, Largman C. Stage- and lineage-specific expression of the HOXA10 homeohox gene in normal and leukemic hematopoietic cells Experimental Hematology. 23: 1160-1166. PMID 7556525  1
1994 Sauvageau G, Lansdorp PM, Eaves CJ, Hogge DE, Dragowska WH, Reid DS, Largman C, Lawrence HJ, Humphries RK. Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells Proceedings of the National Academy of Sciences of the United States of America. 91: 12223-12227. PMID 7527557 DOI: 10.1073/Pnas.91.25.12223  1
1991 Routy JP, Beaulieu R, Monte M, Saint-Louis J, Sauvageau G, Toma E. Immunologic thrombocytopenia followed by thrombotic thrombocytopenic purpura in two HIV1 patients. American Journal of Hematology. 38: 327-8. PMID 1746543 DOI: 10.1002/ajh.2830380414  1
1990 Sauvageau G, Stocco R, Kasparian S, Menezes J. Epstein-Barr virus receptor expression on human CD8+ (cytotoxic/suppressor) T lymphocytes Journal of General Virology. 71: 379-386. PMID 2155291 DOI: 10.1099/0022-1317-71-2-379  1
1990 Stocco R, Sauvageau G, Stefanescu I, Menezes J. Effect of monoclonal antibodies to epstein-barr virus envelope glycoproteins on epstein-barr virus neutralization and binding to target cell receptors: A comparative analysis Intervirology. 31: 295-300. PMID 1703135 DOI: 10.1159/000150165  1
1988 Stocco R, Sauvageau G, Menezes J. Differences in Epstein-Barr virus (EBV) receptors expression on various human lymphoid targets and their significance to EBV-cell interaction Virus Research. 11: 209-225. PMID 2848382 DOI: 10.1016/0168-1702(88)90084-6  1
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