Brian B. Gowen, Ph.D. - Publications

Affiliations: 
2000 University of South Carolina, Columbia, SC 
Area:
Cell Biology, Molecular Biology

82 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Chapman NS, Hulswit RJG, Westover JLB, Stass R, Paesen GC, Binshtein E, Reidy JX, Engdahl TB, Handal LS, Flores A, Gowen BB, Bowden TA, Crowe JE. Multifunctional human monoclonal antibody combination mediates protection against Rift Valley fever virus at low doses. Nature Communications. 14: 5650. PMID 37704627 DOI: 10.1038/s41467-023-41171-3  0.313
2022 Westover JB, Naik S, Bailey KW, Wandersee L, Gantla VR, Hickerson BT, McCormack K, Henkel G, Gowen BB. Severe mammarenaviral disease in guinea pigs effectively treated by an orally bioavailable fusion inhibitor, alone or in combination with favipiravir. Antiviral Research. 208: 105444. PMID 36243175 DOI: 10.1016/j.antiviral.2022.105444  0.482
2021 Julander JG, Demarest JF, Taylor R, Gowen BB, Walling DM, Mathis A, Babu YS. An update on the progress of galidesivir (BCX4430), a broad-spectrum antiviral. Antiviral Research. 195: 105180. PMID 34551346 DOI: 10.1016/j.antiviral.2021.105180  0.343
2021 Gowen BB, Naik S, Westover JB, Brown ER, Gantla VR, Fetsko A, Dagley AL, Blotter DJ, Anderson N, McCormack K, Henkel G. Potent inhibition of arenavirus infection by a novel fusion inhibitor. Antiviral Research. 105125. PMID 34197863 DOI: 10.1016/j.antiviral.2021.105125  0.373
2021 Gowen BB, Hickerson BT, York J, Westover JB, Sefing EJ, Bailey KW, Wandersee L, Nunberg JH. Second-generation live-attenuated Candid#1 vaccine virus resists reversion and protects against lethal Junín virus infection in guinea pigs. Journal of Virology. PMID 33952638 DOI: 10.1128/JVI.00397-21  0.398
2021 Chapman NS, Zhao H, Kose N, Westover JB, Kalveram B, Bombardi R, Rodriguez J, Sutton R, Genualdi J, LaBeaud AD, Mutuku FM, Pittman PR, Freiberg AN, Gowen BB, Fremont DH, et al. Potent neutralization of Rift Valley fever virus by human monoclonal antibodies through fusion inhibition. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33782133 DOI: 10.1073/pnas.2025642118  0.318
2020 Ranadheera C, Valcourt EJ, Warner BM, Poliquin G, Rosenke K, Frost K, Tierney K, Saturday G, Miao J, Westover JB, Gowen BB, Booth S, Feldmann H, Wang Z, Safronetz D. Characterization of a novel STAT 2 knock-out hamster model of Crimean-Congo hemorrhagic fever virus pathogenesis. Scientific Reports. 10: 12378. PMID 32704046 DOI: 10.1038/S41598-020-69054-3  0.533
2020 Hawman DW, Haddock E, Meade-White K, Nardone G, Feldmann F, Hanley PW, Lovaglio J, Scott D, Komeno T, Nakajima N, Furuta Y, Gowen BB, Feldmann H. Efficacy of favipiravir (T-705) against Crimean-Congo hemorrhagic fever virus infection in cynomolgus macaques. Antiviral Research. 104858. PMID 32645335 DOI: 10.1016/J.Antiviral.2020.104858  0.568
2020 Hickerson BT, Sefing EJ, Bailey KW, Van Wettere AJ, Penichet ML, Gowen BB. Type I interferon underlies severe disease associated with Junín virus infection in mice. Elife. 9. PMID 32452770 DOI: 10.7554/Elife.55352  0.502
2020 Hickerson BT, Sefing EJ, Bailey KW, Wettere AJV, Penichet ML, Gowen BB. Author response: Type I interferon underlies severe disease associated with Junín virus infection in mice Elife. DOI: 10.7554/Elife.55352.Sa2  0.507
2019 Hickerson BT, Westover JB, Wang Z, Lee YM, Gowen BB. Guinea pig transferrin receptor 1 mediates cellular entry of Junín virus and other pathogenic New World arenaviruses. Journal of Virology. PMID 31748396 DOI: 10.1128/Jvi.01278-19  0.558
2019 Westover JB, Hickerson BT, Van Wettere AJ, Hurst BL, Kurz JP, Dagley A, Wülfroth P, Komeno T, Furuta Y, Steiner T, Gowen BB. Vascular Leak and Hypercytokinemia Associated with Severe Fever with Thrombocytopenia Syndrome Virus Infection in Mice. Pathogens (Basel, Switzerland). 8. PMID 31546590 DOI: 10.3390/Pathogens8040158  0.463
2018 Madu IG, Files M, Gharaibeh DN, Moore AL, Jung KH, Gowen BB, Dai D, Jones KF, Tyavanagimatt SR, Burgeson JR, Korth MJ, Bedard KM, Iadonato SP, Amberg SM. A potent Lassa virus antiviral targets an arenavirus virulence determinant. Plos Pathogens. 14: e1007439. PMID 30576397 DOI: 10.1371/Journal.Ppat.1007439  0.487
2018 Hickerson BT, Westover JB, Van Wettere AJ, Rigas JD, Miao J, Conrad BL, Motter NE, Wang Z, Gowen BB. Pathogenesis of Rift Valley Fever Virus Aerosol Infection in Knockout Hamsters. Viruses. 10. PMID 30463176 DOI: 10.3390/V10110651  0.52
2018 Smee DF, Jung KH, Westover J, Gowen BB. 2'-Fluoro-2'-deoxycytidine is a broad-spectrum inhibitor of bunyaviruses in vitro and in phleboviral disease mouse models. Antiviral Research. PMID 30339848 DOI: 10.1016/J.Antiviral.2018.10.013  0.505
2018 Atkins C, Miao J, Kalveram B, Juelich T, Smith JK, Perez D, Zhang L, Westover JLB, Van Wettere AJ, Gowen BB, Wang Z, Freiberg AN. Natural History and Pathogenesis of Wild-Type Marburg Virus Infection in STAT2 Knockout Hamsters. The Journal of Infectious Diseases. PMID 30192975 DOI: 10.1093/Infdis/Jiy457  0.566
2018 Hawman DW, Haddock E, Meade-White K, Williamson B, Hanley PW, Rosenke K, Komeno T, Furuta Y, Gowen BB, Feldmann H. Favipiravir (T-705) but not ribavirin is effective against two distinct strains of Crimean-Congo hemorrhagic fever virus in mice. Antiviral Research. PMID 29936152 DOI: 10.1016/J.Antiviral.2018.06.013  0.505
2018 Rosenke K, Feldmann H, Westover JB, Hanley PW, Martellaro C, Feldmann F, Saturday G, Lovaglio J, Scott DP, Furuta Y, Komeno T, Gowen BB, Safronetz D. Use of Favipiravir to Treat Lassa Virus Infection in Macaques. Emerging Infectious Diseases. 24. PMID 29882740 DOI: 10.3201/Eid2409.180233  0.544
2018 Westover JB, Mathis A, Taylor R, Wandersee L, Bailey KW, Sefing EJ, Hickerson BT, Jung KH, Sheridan WP, Gowen BB. Galidesivir limits Rift Valley fever virus infection and disease in Syrian golden hamsters. Antiviral Research. PMID 29864447 DOI: 10.1016/J.Antiviral.2018.05.013  0.576
2018 Hickerson BT, Westover JB, Jung KH, Komeno T, Furuta Y, Gowen BB. Effective Treatment of Experimental Lymphocytic Choriomeningitis Virus Infection: Consideration of Favipiravir for use with Infected Organ Transplant Recipients. The Journal of Infectious Diseases. PMID 29762684 DOI: 10.1093/Infdis/Jiy159  0.47
2017 Westover JB, Rigas JD, Van Wettere AJ, Li R, Hickerson BT, Jung KH, Miao J, Reynolds ES, Conrad BL, Nielson S, Furuta Y, Thangamani S, Wang Z, Gowen BB. Heartland virus infection in hamsters deficient in type I interferon signaling: Protracted disease course ameliorated by favipiravir. Virology. 511: 175-183. PMID 28865344 DOI: 10.1016/J.Virol.2017.08.004  0.54
2017 Gowen BB, Westover JB, Sefing EJ, Van Wettere AJ, Bailey KW, Wandersee L, Komeno T, Furuta Y. Enhanced protection against experimental Junin virus infection through the use of a modified favipiravir loading dose strategy. Antiviral Research. PMID 28780425 DOI: 10.1016/J.Antiviral.2017.07.019  0.506
2017 Gowen BB, Hickerson BT. Hemorrhagic fever of bunyavirus etiology: disease models and progress towards new therapies. Journal of Microbiology (Seoul, Korea). 55: 183-195. PMID 28243938 DOI: 10.1007/S12275-017-7029-8  0.474
2016 Gowen BB, Westover JB, Miao J, Van Wettere AJ, Rigas JD, Hickerson BT, Jung KH, Li R, Conrad BL, Nielson S, Furuta Y, Wang Z. Modeling severe fever with thrombocytopenia syndrome virus infection in golden Syrian hamsters: Importance of STAT2 in preventing disease and effective treatment with favipiravir. Journal of Virology. PMID 27881648 DOI: 10.1128/Jvi.01942-16  0.569
2015 Westover JB, Sefing EJ, Bailey KW, Van Wettere AJ, Jung KH, Dagley A, Wandersee L, Downs B, Smee DF, Furuta Y, Bray M, Gowen BB. Low-dose ribavirin potentiates the antiviral activity of favipiravir against hemorrhagic fever viruses. Antiviral Research. PMID 26711718 DOI: 10.1016/J.Antiviral.2015.12.006  0.533
2015 Safronetz D, Rosenke K, Westover JB, Martellaro C, Okumura A, Furuta Y, Geisbert J, Saturday G, Komeno T, Geisbert TW, Feldmann H, Gowen BB. The broad-spectrum antiviral favipiravir protects guinea pigs from lethal Lassa virus infection post-disease onset. Scientific Reports. 5: 14775. PMID 26456301 DOI: 10.1038/Srep14775  0.565
2015 Gowen BB, Sefing EJ, Westover JB, Smee DF, Hagloch J, Furuta Y, Hall JO. Alterations in favipiravir (T-705) pharmacokinetics and biodistribution in a hamster model of viral hemorrhagic fever. Antiviral Research. 121: 132-7. PMID 26186980 DOI: 10.1016/J.Antiviral.2015.07.003  0.547
2015 Gowen BB, Westover JB, Sefing EJ, Bailey KW, Nishiyama S, Wandersee L, Scharton D, Jung KH, Ikegami T. MP-12 virus containing the clone 13 deletion in the NSs gene prevents lethal disease when administered after Rift Valley fever virus infection in hamsters. Frontiers in Microbiology. 6: 651. PMID 26175722 DOI: 10.3389/Fmicb.2015.00651  0.467
2015 Scharton D, Van Wettere AJ, Bailey KW, Vest Z, Westover JB, Siddharthan V, Gowen BB. Rift Valley fever virus infection in golden Syrian hamsters. Plos One. 10: e0116722. PMID 25607955 DOI: 10.1371/Journal.Pone.0116722  0.536
2015 Falcinelli S, Gowen BB, Trost B, Napper S, Kusalik A, Johnson RF, Safronetz D, Prescott J, Wahl-Jensen V, Jahrling PB, Kindrachuk J. Characterization of the host response to pichinde virus infection in the Syrian golden hamster by species-specific kinome analysis. Molecular & Cellular Proteomics : McP. 14: 646-57. PMID 25573744 DOI: 10.1074/Mcp.M114.045443  0.443
2014 Smith DR, Holbrook MR, Gowen BB. Animal models of viral hemorrhagic fever. Antiviral Research. 112: 59-79. PMID 25448088 DOI: 10.1016/J.Antiviral.2014.10.001  0.457
2014 Dagley A, Ennis J, Turner JD, Rood KA, Van Wettere AJ, Gowen BB, Julander JG. Protection against Chikungunya virus induced arthralgia following prophylactic treatment with adenovirus vectored interferon (mDEF201). Antiviral Research. 108: 1-9. PMID 24833276 DOI: 10.1016/J.Antiviral.2014.05.004  0.551
2014 Gowen BB, Ennis J, Bailey KW, Vest Z, Scharton D, Sefing EJ, Turner JD. Single-dose intranasal treatment with DEF201 (adenovirus vectored consensus interferon) prevents lethal disease due to Rift Valley fever virus challenge. Viruses. 6: 1410-23. PMID 24662673 DOI: 10.3390/V6031410  0.527
2014 Scharton D, Bailey KW, Vest Z, Westover JB, Kumaki Y, Van Wettere A, Furuta Y, Gowen BB. Favipiravir (T-705) protects against peracute Rift Valley fever virus infection and reduces delayed-onset neurologic disease observed with ribavirin treatment. Antiviral Research. 104: 84-92. PMID 24486952 DOI: 10.1016/J.Antiviral.2014.01.016  0.557
2014 Gowen BB, Jung KH, Sefing EJ, Wong MH, Westover JB, Smee DF. Activity of a phenolic dibenzylsulfide against New World arenavirus infections. Antiviral Chemistry & Chemotherapy. 23: 151-9. PMID 23337126 DOI: 10.3851/Imp2532  0.511
2013 Gowen BB, Juelich TL, Sefing EJ, Brasel T, Smith JK, Zhang L, Tigabu B, Hill TE, Yun T, Pietzsch C, Furuta Y, Freiberg AN. Favipiravir (T-705) inhibits Junín virus infection and reduces mortality in a guinea pig model of Argentine hemorrhagic fever. Plos Neglected Tropical Diseases. 7: e2614. PMID 24386500 DOI: 10.1371/Journal.Pntd.0002614  0.483
2013 Furuta Y, Gowen BB, Takahashi K, Shiraki K, Smee DF, Barnard DL. Favipiravir (T-705), a novel viral RNA polymerase inhibitor. Antiviral Research. 100: 446-54. PMID 24084488 DOI: 10.1016/J.Antiviral.2013.09.015  0.424
2013 Safronetz D, Falzarano D, Scott DP, Furuta Y, Feldmann H, Gowen BB. Antiviral efficacy of favipiravir against two prominent etiological agents of hantavirus pulmonary syndrome. Antimicrobial Agents and Chemotherapy. 57: 4673-80. PMID 23856782 DOI: 10.1128/Aac.00886-13  0.485
2013 Sefing EJ, Wong MH, Larson DP, Hurst BL, Van Wettere AJ, Schneller SW, Gowen BB. Vascular leak ensues a vigorous proinflammatory cytokine response to Tacaribe arenavirus infection in AG129 mice. Virology Journal. 10: 221. PMID 23816343 DOI: 10.1186/1743-422X-10-221  0.498
2013 Gowen BB, Bailey KW, Scharton D, Vest Z, Westover JB, Skirpstunas R, Ikegami T. Post-exposure vaccination with MP-12 lacking NSs protects mice against lethal Rift Valley fever virus challenge. Antiviral Research. 98: 135-43. PMID 23523764 DOI: 10.1016/J.Antiviral.2013.03.009  0.371
2012 Gowen BB, Ennis J, Sefing EJ, Wong MH, Jung KH, Turner JD. Extended protection against phlebovirus infection conferred by recombinant adenovirus expressing consensus interferon (DEF201). Antimicrobial Agents and Chemotherapy. 56: 4168-74. PMID 22615273 DOI: 10.1128/Aac.00376-12  0.463
2011 Gowen BB, Bray M. Progress in the experimental therapy of severe arenaviral infections. Future Microbiology. 6: 1429-41. PMID 22122440 DOI: 10.2217/Fmb.11.132  0.511
2011 Gowen BB, Ennis J, Russell A, Sefing EJ, Wong MH, Turner J. Use of recombinant adenovirus vectored consensus IFN-α to avert severe arenavirus infection. Plos One. 6: e26072. PMID 22039436 DOI: 10.1371/Journal.Pone.0026072  0.523
2011 Mendenhall M, Russell A, Smee DF, Hall JO, Skirpstunas R, Furuta Y, Gowen BB. Effective oral favipiravir (T-705) therapy initiated after the onset of clinical disease in a model of arenavirus hemorrhagic Fever. Plos Neglected Tropical Diseases. 5: e1342. PMID 22022624 DOI: 10.1371/Journal.Pntd.0001342  0.449
2011 Buys KK, Jung KH, Smee DF, Furuta Y, Gowen BB. Maporal virus as a surrogate for pathogenic New World hantaviruses and its inhibition by favipiravir. Antiviral Chemistry & Chemotherapy. 21: 193-200. PMID 21566265 DOI: 10.3851/Imp1729  0.49
2011 Mendenhall M, Russell A, Juelich T, Messina EL, Smee DF, Freiberg AN, Holbrook MR, Furuta Y, de la Torre JC, Nunberg JH, Gowen BB. T-705 (favipiravir) inhibition of arenavirus replication in cell culture. Antimicrobial Agents and Chemotherapy. 55: 782-7. PMID 21115797 DOI: 10.1128/Aac.01219-10  0.484
2011 Gowen BB, Mendenhall M, Russell A, Smee DF, Furuta Y. Favipiravir (T-705) Treatment of Experimental Arenaviral Infection Initiated after the Onset of Clinical Disease Antiviral Research. 90. DOI: 10.1016/J.Antiviral.2011.03.093  0.408
2010 Gowen BB, Wong MH, Larson D, Ye W, Jung KH, Sefing EJ, Skirpstunas R, Smee DF, Morrey JD, Schneller SW. Development of a new tacaribe arenavirus infection model and its use to explore antiviral activity of a novel aristeromycin analog. Plos One. 5. PMID 20862280 DOI: 10.1371/Journal.Pone.0012760  0.496
2010 Gowen BB, Julander JG, London NR, Wong MH, Larson D, Morrey JD, Li DY, Bray M. Assessing changes in vascular permeability in a hamster model of viral hemorrhagic fever. Virology Journal. 7: 240. PMID 20846417 DOI: 10.1186/1743-422X-7-240  0.417
2010 Gowen BB, Wong MH, Jung KH, Smee DF, Morrey JD, Furuta Y. Efficacy of favipiravir (T-705) and T-1106 pyrazine derivatives in phlebovirus disease models. Antiviral Research. 86: 121-7. PMID 19874853 DOI: 10.1016/J.Antiviral.2009.10.015  0.455
2010 Gowen B, Jung K, Larson D, Ye W, Morrey J, Smee D, Schneller S. A New Tacaribe Arenavirus Infection Model to Explore the Antiviral Activity of a Novel Aristeromycin Analog Antiviral Research. 86: A55. DOI: 10.1016/J.Antiviral.2010.02.437  0.434
2010 Gowen B, Barnard D, Wong M, Larson D, Wu J, Ennis J, Morrey J, Turner J. Single-dose Intranasal Delivery with DEF201 (Adenovirus Vectored Mouse Interferon-α) Protects Against Phlebovirus and Sars Coronavirus Challenge Antiviral Research. 86: A34. DOI: 10.1016/J.Antiviral.2010.02.376  0.308
2009 Mendenhall M, Wong MH, Skirpstunas R, Morrey JD, Gowen BB. Punta Toro virus (Bunyaviridae, Phlebovirus) infection in mice: strain differences in pathogenesis and host interferon response. Virology. 395: 143-51. PMID 19783024 DOI: 10.1016/J.Virol.2009.09.003  0.5
2009 Furuta Y, Takahashi K, Shiraki K, Sakamoto K, Smee DF, Barnard DL, Gowen BB, Julander JG, Morrey JD. T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections. Antiviral Research. 82: 95-102. PMID 19428599 DOI: 10.1016/J.Antiviral.2009.02.198  0.506
2009 Durán N, Gowen BB, Costa FT, Justo GZ, Brocchi M, Nunes OS, Nunes IS. A biotechnological product and its potential as a new immunomodulator for treatment of animal phlebovirus infection: Punta Toro virus. Antiviral Research. 83: 143-7. PMID 19393266 DOI: 10.1016/J.Antiviral.2009.04.006  0.544
2009 Gowen BB, Fairman J, Dow S, Troyer R, Wong MH, Jung KH, Melby PC, Morrey JD. Prophylaxis with cationic liposome-DNA complexes protects hamsters from phleboviral disease: importance of liposomal delivery and CpG motifs. Antiviral Research. 81: 37-46. PMID 18840471 DOI: 10.1016/J.Antiviral.2008.09.001  0.38
2009 Gowen B, Wong M, Jung K, Smee D, Morrey J, Furuta Y. Pyrazine Derivative Treatment of Phleboviral Infection in Cell Culture and Rodent Model Systems Antiviral Research. 82: A39. DOI: 10.1016/J.Antiviral.2009.02.081  0.376
2008 Gowen BB, Smee DF, Wong MH, Hall JO, Jung KH, Bailey KW, Stevens JR, Furuta Y, Morrey JD. Treatment of late stage disease in a model of arenaviral hemorrhagic fever: T-705 efficacy and reduced toxicity suggests an alternative to ribavirin. Plos One. 3: e3725. PMID 19008960 DOI: 10.1371/Journal.Pone.0003725  0.504
2008 Subramanian GM, Moore PA, Gowen BB, Olsen AL, Barnard DL, Paragas J, Hogan RJ, Sidwell RW. Potent in vitro activity of the albumin fusion type 1 interferons (albumin-interferon-alpha and albumin-interferon-beta) against RNA viral agents of bioterrorism and the severe acute respiratory syndrome (SARS) virus. Chemotherapy. 54: 176-80. PMID 18560223 DOI: 10.1159/000140361  0.317
2008 Gowen BB, Judge JW, Wong MH, Jung KH, Aylsworth CF, Melby PC, Rosenberg B, Morrey JD. Immunoprophylaxis of Punta Toro virus (Phlebovirus, Bunyaviridae) infection in hamsters with recombinant Eimeria profilin-like antigen. International Immunopharmacology. 8: 1089-94. PMID 18550012 DOI: 10.1016/J.Intimp.2008.03.019  0.473
2008 Gowen BB, Wong MH, Jung KH, Blatt LM, Sidwell RW. Prophylactic and therapeutic intervention of Punta Toro virus (Phlebovirus, Bunyaviridae) infection in hamsters with interferon alfacon-1. Antiviral Research. 77: 215-24. PMID 18222548 DOI: 10.1016/J.Antiviral.2007.12.002  0.568
2008 Smee DF, Gowen BB, Wandersee MK, Wong MH, Skirpstunas RT, Baldwin TJ, Hoopes JD, Sidwell RW. Differential pathogenesis of cowpox virus intranasal infections in mice induced by low and high inoculum volumes and effects of cidofovir treatment. International Journal of Antimicrobial Agents. 31: 352-9. PMID 18206353 DOI: 10.1016/J.Ijantimicag.2007.11.013  0.546
2008 Gowen BB, Holbrook MR. Animal models of highly pathogenic RNA viral infections: hemorrhagic fever viruses. Antiviral Research. 78: 79-90. PMID 18036672 DOI: 10.1016/J.Antiviral.2007.10.002  0.527
2008 Holbrook MR, Gowen BB. Animal models of highly pathogenic RNA viral infections: encephalitis viruses. Antiviral Research. 78: 69-78. PMID 18031836 DOI: 10.1016/J.Antiviral.2007.10.004  0.47
2008 Jung K, Judge JW, Wong M, Melby PC, Rosenberg B, Morrey JD, Gowen BB. Immunoprophylaxis of Phleboviral Infection in Hamsters with Recombinant Eimeria Protozoan Surface Antigen Antiviral Research. 78: A58. DOI: 10.1016/J.Antiviral.2008.01.123  0.367
2008 Gowen B, Wong M, Jung K, Bailey K, Furuta Y, Morrey J. Therapy of Advanced Arenaviral Infection in Hamsters with T-705 Antiviral Research. 78: A57. DOI: 10.1016/J.Antiviral.2008.01.119  0.37
2007 Ma X, Liu Y, Gowen BB, Graviss EA, Clark AG, Musser JM. Full-exon resequencing reveals toll-like receptor variants contribute to human susceptibility to tuberculosis disease. Plos One. 2: e1318. PMID 18091991 DOI: 10.1371/Journal.Pone.0001318  0.301
2007 Selvam P, Vijayalakshimi P, Smee DF, Gowen BB, Julander JG, Day CW, Barnard DL. Novel 3-sulphonamido-quinazolin-4(3H)-one derivatives: microwave-assisted synthesis and evaluation of antiviral activities against respiratory and biodefense viruses. Antiviral Chemistry & Chemotherapy. 18: 301-5. PMID 18046963 DOI: 10.1177/095632020701800506  0.363
2007 Gowen BB, Wong MH, Jung KH, Sanders AB, Mendenhall M, Bailey KW, Furuta Y, Sidwell RW. In vitro and in vivo activities of T-705 against arenavirus and bunyavirus infections. Antimicrobial Agents and Chemotherapy. 51: 3168-76. PMID 17606691 DOI: 10.1128/Aac.00356-07  0.518
2007 Gowen BB, Wong MH, Jung KH, Sanders AB, Mitchell WM, Alexopoulou L, Flavell RA, Sidwell RW. TLR3 is essential for the induction of protective immunity against Punta Toro Virus infection by the double-stranded RNA (dsRNA), poly(I:C12U), but not Poly(I:C): differential recognition of synthetic dsRNA molecules. Journal of Immunology (Baltimore, Md. : 1950). 178: 5200-8. PMID 17404303 DOI: 10.4049/Jimmunol.178.8.5200  0.451
2007 GOWEN B, JUNG K, MENDENHALL M, GAVRILOVSKAYA I, VENKATRAMAN S, MACKOW E, SIDWELL R. Cytopathic Maporal Hantavirus Infection of Vero E6 Cells Antiviral Research. 74: A78-A78. DOI: 10.1016/J.Antiviral.2007.01.132  0.37
2007 Jung K, Wong M, Furuta Y, Sanders A, Mendenhall M, Bailey K, Sidwell R, Gowen B. 40In Vitro and In Vivo Activity of T-705 Against Arenavirus and Bunyavirus Infections Antiviral Research. 74. DOI: 10.1016/J.Antiviral.2007.01.048  0.398
2006 Gowen BB, Smee DF, Wong MH, Pace AM, Jung KH, Bailey KW, Blatt LM, Sidwell RW. Combinatorial ribavirin and interferon alfacon-1 therapy of acute arenaviral disease in hamsters. Antiviral Chemistry & Chemotherapy. 17: 175-83. PMID 17066896 DOI: 10.1177/095632020601700402  0.481
2006 Gowen BB, Hoopes JD, Wong MH, Jung KH, Isakson KC, Alexopoulou L, Flavell RA, Sidwell RW. TLR3 deletion limits mortality and disease severity due to Phlebovirus infection. Journal of Immunology (Baltimore, Md. : 1950). 177: 6301-7. PMID 17056560 DOI: 10.4049/Jimmunol.177.9.6301  0.486
2006 Gowen BB, Smee DF, Wong MH, Judge JW, Jung KH, Bailey KW, Pace AM, Rosenberg B, Sidwell RW. Recombinant Eimeria protozoan protein elicits resistance to acute phlebovirus infection in mice but not hamsters. Antimicrobial Agents and Chemotherapy. 50: 2023-9. PMID 16723561 DOI: 10.1128/Aac.01473-05  0.481
2006 Gowen BB, Fairman J, Smee DF, Wong MH, Jung KH, Pace AM, Heiner ML, Bailey KW, Dow SW, Sidwell RW. Protective immunity against acute phleboviral infection elicited through immunostimulatory cationic liposome-DNA complexes. Antiviral Research. 69: 165-72. PMID 16430975 DOI: 10.1016/J.Antiviral.2005.12.002  0.519
2005 Gowen BB, Barnard DL, Smee DF, Wong MH, Pace AM, Jung KH, Winslow SG, Bailey KW, Blatt LM, Sidwell RW. Interferon alfacon-1 protects hamsters from lethal pichinde virus infection. Antimicrobial Agents and Chemotherapy. 49: 2378-86. PMID 15917537 DOI: 10.1128/Aac.49.6.2378-2386.2005  0.524
2005 Sebbane F, Gardner D, Long D, Gowen BB, Hinnebusch BJ. Kinetics of disease progression and host response in a rat model of bubonic plague. The American Journal of Pathology. 166: 1427-39. PMID 15855643 DOI: 10.1016/S0002-9440(10)62360-7  0.446
2005 Graham MR, Virtaneva K, Porcella SF, Barry WT, Gowen BB, Johnson CR, Wright FA, Musser JM. Group A Streptococcus transcriptome dynamics during growth in human blood reveals bacterial adaptive and survival strategies. The American Journal of Pathology. 166: 455-65. PMID 15681829 DOI: 10.1016/S0002-9440(10)62268-7  0.356
2002 Hoe NP, Ireland RM, DeLeo FR, Gowen BB, Dorward DW, Voyich JM, Liu M, Burns EH, Culnan DM, Bretscher A, Musser JM. Insight into the molecular basis of pathogen abundance: group A Streptococcus inhibitor of complement inhibits bacterial adherence and internalization into human cells. Proceedings of the National Academy of Sciences of the United States of America. 99: 7646-51. PMID 12032337 DOI: 10.1073/Pnas.112039899  0.313
2001 Gowen BB, Borg TK, Ghaffar A, Mayer EP. The collagenous domain of class A scavenger receptors is involved in macrophage adhesion to collagens Journal of Leukocyte Biology. 69: 575-582. PMID 11310843 DOI: 10.1189/Jlb.69.4.575  0.484
2000 Gowen BB, Borg TK, Ghaffar A, Mayer EP. Selective adhesion of macrophages to denatured forms of type I collagen is mediated by scavenger receptors Matrix Biology. 19: 61-71. PMID 10686426 DOI: 10.1016/S0945-053X(99)00052-9  0.492
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