Nathan Lewis Clark, Ph.D. - Publications

Affiliations: 
Cornell University, Ithaca, NY, United States 
Area:
adaptive evolution, co-evolutionary networks
Website:
http://mbg.cornell.edu/cals/mbg/research/aquadro-lab/currentmembers.cfm#Clark

37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Kopania EEK, Thomas GWC, Hutter CR, Mortimer SME, Callahan CM, Roycroft E, Achmadi AS, Breed WG, Clark NL, Esselstyn JA, Rowe KC, Good JM. Molecular evolution of male reproduction across species with highly divergent sperm morphology in diverse murine rodents. Biorxiv : the Preprint Server For Biology. PMID 37693452 DOI: 10.1101/2023.08.30.555585  0.437
2023 Graham AM, Jamison JM, Bustos M, Cournoyer C, Michaels A, Presnell JS, Richter R, Crocker DE, Fustukjian A, Hunter ME, Rea LD, Marsillach J, Furlong CE, Meyer WK, Clark NL. Reduction of Paraoxonase expression followed by inactivation across independent semiaquatic mammals suggests stepwise path to pseudogenization. Molecular Biology and Evolution. PMID 37146172 DOI: 10.1093/molbev/msad104  0.7
2023 Lucas SAM, Graham AM, Presnell JS, Clark NL. Highly Dynamic Gene Family Evolution Suggests Changing Roles for PON Genes Within Metazoa. Genome Biology and Evolution. PMID 36718542 DOI: 10.1093/gbe/evad011  0.651
2022 Kowalczyk A, Chikina M, Clark NL. Complementary evolution of coding and noncoding sequence underlies mammalian hairlessness. Elife. 11. PMID 36342464 DOI: 10.7554/eLife.76911  0.313
2021 Keeble S, Firman RC, Sarver BAJ, Clark NL, Simmons LW, Dean MD. Evolutionary, proteomic, and experimental investigations suggest the extracellular matrix of cumulus cells mediates fertilization outcomes. Biology of Reproduction. PMID 34007991 DOI: 10.1093/biolre/ioab082  0.425
2021 Furman CM, Elbashir R, Pannafino G, Clark NL, Alani E. Experimental exchange of paralogous domains in the MLH family provides evidence of sub-functionalization after gene duplication. G3 (Bethesda, Md.). PMID 33871573 DOI: 10.1093/g3journal/jkab111  0.397
2020 Kowalczyk A, Partha R, Clark NL, Chikina M. Pan-mammalian analysis of molecular constraints underlying extended lifespan. Elife. 9. PMID 32043462 DOI: 10.7554/Elife.51089  0.438
2019 Plakke MS, Walker JL, Lombardo JB, Goetz BJ, Pacella GN, Durrant JD, Clark NL, Morehouse NI. Characterization of Female Reproductive Proteases in a Butterfly from Functional and Evolutionary Perspectives. Physiological and Biochemical Zoology : Pbz. 92: 579-590. PMID 31584859 DOI: 10.1086/705722  0.436
2019 Brunette GJ, Jamalruddin MA, Baldock RA, Clark NL, Bernstein KA. Evolution-based screening enables genome-wide prioritization and discovery of DNA repair genes. Proceedings of the National Academy of Sciences of the United States of America. PMID 31501324 DOI: 10.1073/Pnas.1906559116  0.303
2019 Kowalczyk A, Meyer WK, Partha R, Mao W, Clark NL, Chikina M. RERconverge: an R package for associating evolutionary rates with convergent traits. Bioinformatics (Oxford, England). PMID 31192356 DOI: 10.1093/Bioinformatics/Btz468  0.428
2019 Partha R, Kowalczyk A, Clark N, Chikina M. Robust method for detecting convergent shifts in evolutionary rates. Molecular Biology and Evolution. PMID 31077321 DOI: 10.1093/Molbev/Msz107  0.392
2019 Raza Q, Choi JY, Li Y, O'Dowd RM, Watkins SC, Chikina M, Hong Y, Clark NL, Kwiatkowski AV. Evolutionary rate covariation analysis of E-cadherin identifies Raskol as a regulator of cell adhesion and actin dynamics in Drosophila. Plos Genetics. 15: e1007720. PMID 30763317 DOI: 10.1371/Journal.Pgen.1007720  0.585
2018 Meyer WK, Jamison J, Richter R, Woods SE, Partha R, Kowalczyk A, Kronk C, Chikina M, Bonde RK, Crocker DE, Gaspard J, Lanyon JM, Marsillach J, Furlong CE, Clark NL. Ancient convergent losses of yield potential risks for modern marine mammals. Science (New York, N.Y.). 361: 591-594. PMID 30093596 DOI: 10.1126/Science.Aap7714  0.343
2018 Nallu S, Hill JA, Don K, Sahagun C, Zhang W, Meslin C, Snell-Rood E, Clark NL, Morehouse NI, Bergelson J, Wheat CW, Kronforst MR. The molecular genetic basis of herbivory between butterflies and their host plants. Nature Ecology & Evolution. PMID 30076351 DOI: 10.1038/S41559-018-0629-9  0.306
2017 Partha R, Chauhan BK, Ferreira Z, Robinson JD, Lathrop K, Nischal KK, Chikina M, Clark NL. Subterranean mammals show convergent regression in ocular genes and enhancers, along with adaptation to tunneling. Elife. 6. PMID 29035697 DOI: 10.7554/Elife.25884  0.435
2017 Meslin C, Cherwin TS, Plakke MS, Small BS, Goetz BJ, Morehouse NI, Clark NL. Structural complexity and molecular heterogeneity of a butterfly ejaculate reflect a complex history of selection. Proceedings of the National Academy of Sciences of the United States of America. PMID 28630352 DOI: 10.1073/Pnas.1707680114  0.51
2017 Partha R, Chauhan BK, Ferreira Z, Robinson JD, Lathrop K, Nischal KK, Chikina M, Clark NL. Author response: Subterranean mammals show convergent regression in ocular genes and enhancers, along with adaptation to tunneling Elife. DOI: 10.7554/Elife.25884.032  0.324
2016 Chikina M, Robinson JD, Clark NL. Hundreds of genes experienced convergent shifts in selective pressure in marine mammals. Molecular Biology and Evolution. PMID 27329977 DOI: 10.1093/Molbev/Msw112  0.44
2015 Wolfe NW, Clark NL. ERC analysis: web-based inference of gene function via evolutionary rate covariation. Bioinformatics (Oxford, England). PMID 26243019 DOI: 10.1093/Bioinformatics/Btv454  0.418
2015 Mangels R, Young B, Keeble S, Ardekani R, Meslin C, Ferreira Z, Clark NL, Good JM, Dean MD. Genetic and phenotypic influences on copulatory plug survival in mice. Heredity. PMID 26103947 DOI: 10.1038/Hdy.2015.50  0.467
2015 Plakke MS, Deutsch AB, Meslin C, Clark NL, Morehouse NI. Dynamic digestive physiology of a female reproductive organ in a polyandrous butterfly. The Journal of Experimental Biology. 218: 1548-55. PMID 25994634 DOI: 10.1242/Jeb.118323  0.471
2015 Hancks DC, Hartley MK, Hagan C, Clark NL, Elde NC. Overlapping Patterns of Rapid Evolution in the Nucleic Acid Sensors cGAS and OAS1 Suggest a Common Mechanism of Pathogen Antagonism and Escape. Plos Genetics. 11: e1005203. PMID 25942676 DOI: 10.1371/Journal.Pgen.1005203  0.403
2015 Meslin C, Plakke MS, Deutsch AB, Small BS, Morehouse NI, Clark NL. Digestive organ in the female reproductive tract borrows genes from multiple organ systems to adopt critical functions. Molecular Biology and Evolution. 32: 1567-80. PMID 25725432 DOI: 10.1093/Molbev/Msv048  0.48
2015 Priedigkeit N, Wolfe N, Clark NL. Evolutionary signatures amongst disease genes permit novel methods for gene prioritization and construction of informative gene-based networks. Plos Genetics. 11: e1004967. PMID 25679399 DOI: 10.1371/Journal.Pgen.1004967  0.372
2015 Godin SK, Meslin C, Kabbinavar F, Bratton-Palmer DS, Hornack C, Mihalevic MJ, Yoshida K, Sullivan M, Clark NL, Bernstein KA. Evolutionary and functional analysis of the invariant SWIM domain in the conserved Shu2/SWS1 protein family from Saccharomyces cerevisiae to Homo sapiens. Genetics. 199: 1023-33. PMID 25659377 DOI: 10.1534/Genetics.114.173518  0.47
2014 Findlay GD, Sitnik JL, Wang W, Aquadro CF, Clark NL, Wolfner MF. Evolutionary rate covariation identifies new members of a protein network required for Drosophila melanogaster female post-mating responses. Plos Genetics. 10: e1004108. PMID 24453993 DOI: 10.1371/Journal.Pgen.1004108  0.762
2013 Clark NL, Alani E, Aquadro CF. Evolutionary rate covariation in meiotic proteins results from fluctuating evolutionary pressure in yeasts and mammals. Genetics. 193: 529-38. PMID 23183665 DOI: 10.1534/Genetics.112.145979  0.776
2012 Clark NL, Alani E, Aquadro CF. Evolutionary rate covariation reveals shared functionality and coexpression of genes. Genome Research. 22: 714-20. PMID 22287101 DOI: 10.1101/Gr.132647.111  0.771
2011 Kelleher ES, Clark NL, Markow TA. Diversity-enhancing selection acts on a female reproductive protease family in four subspecies of Drosophila mojavensis. Genetics. 187: 865-76. PMID 21212232 DOI: 10.1534/Genetics.110.124743  0.515
2010 Clark NL, Aquadro CF. A novel method to detect proteins evolving at correlated rates: identifying new functional relationships between coevolving proteins. Molecular Biology and Evolution. 27: 1152-61. PMID 20044587 DOI: 10.1093/molbev/msp324  0.74
2009 Clark NL, Gasper J, Sekino M, Springer SA, Aquadro CF, Swanson WJ. Coevolution of interacting fertilization proteins. Plos Genetics. 5: e1000570. PMID 19629160 DOI: 10.1371/Journal.Pgen.1000570  0.777
2009 Dean MD, Clark NL, Findlay GD, Karn RC, Yi X, Swanson WJ, MacCoss MJ, Nachman MW. Proteomics and comparative genomic investigations reveal heterogeneity in evolutionary rate of male reproductive proteins in mice (Mus domesticus). Molecular Biology and Evolution. 26: 1733-43. PMID 19420050 DOI: 10.1093/Molbev/Msp094  0.764
2008 Karn RC, Clark NL, Nguyen ED, Swanson WJ. Adaptive evolution in rodent seminal vesicle secretion proteins. Molecular Biology and Evolution. 25: 2301-10. PMID 18718917 DOI: 10.1093/molbev/msn182  0.8
2007 Clark NL, Findlay GD, Yi X, MacCoss MJ, Swanson WJ. Duplication and selection on abalone sperm lysin in an allopatric population. Molecular Biology and Evolution. 24: 2081-90. PMID 17630281 DOI: 10.1093/Molbev/Msm137  0.787
2006 Panhuis TM, Clark NL, Swanson WJ. Rapid evolution of reproductive proteins in abalone and Drosophila. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 361: 261-8. PMID 16612885 DOI: 10.1098/rstb.2005.1793  0.8
2006 Clark NL, Aagaard JE, Swanson WJ. Evolution of reproductive proteins from animals and plants. Reproduction (Cambridge, England). 131: 11-22. PMID 16388004 DOI: 10.1530/Rep.1.00357  0.788
2005 Clark NL, Swanson WJ. Pervasive adaptive evolution in primate seminal proteins. Plos Genetics. 1: e35. PMID 16170411 DOI: 10.1371/journal.pgen.0010035  0.793
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