| Year |
Citation |
Score |
| 2023 |
Goedert M, Crowther RA, Scheres SHW, Spillantini MG. Tau and neurodegeneration. Cytoskeleton (Hoboken, N.J.). PMID 38073060 DOI: 10.1002/cm.21812 |
0.388 |
|
| 2023 |
Schweighauser M, Murzin AG, Macdonald J, Lavenir I, Crowther RA, Scheres SHW, Goedert M. Cryo-EM structures of tau filaments from the brains of mice transgenic for human mutant P301S Tau. Acta Neuropathologica Communications. 11: 160. PMID 37798679 DOI: 10.1186/s40478-023-01658-y |
0.306 |
|
| 2023 |
Schweighauser M, Garringer HJ, Klingstedt T, Nilsson KPR, Masuda-Suzukake M, Murrell JR, Risacher SL, Vidal R, Scheres SHW, Goedert M, Ghetti B, Newell KL. Mutation ∆K281 in MAPT causes Pick's disease. Acta Neuropathologica. 146: 211-226. PMID 37351604 DOI: 10.1007/s00401-023-02598-6 |
0.325 |
|
| 2022 |
Schweighauser M, Arseni D, Bacioglu M, Huang M, Lövestam S, Shi Y, Yang Y, Zhang W, Kotecha A, Garringer HJ, Vidal R, Hallinan GI, Newell KL, Tarutani A, Murayama S, ... ... Goedert M, et al. Age-dependent formation of TMEM106B amyloid filaments in human brains. Nature. PMID 35344985 DOI: 10.1038/s41586-022-04650-z |
0.321 |
|
| 2022 |
Lövestam S, Koh FA, van Knippenberg B, Kotecha A, Murzin AG, Goedert M, Scheres SHW. Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy. Elife. 11. PMID 35244536 DOI: 10.7554/eLife.76494 |
0.359 |
|
| 2022 |
Kovacs GG, Ghetti B, Goedert M. Classification of diseases with accumulation of Tau protein. Neuropathology and Applied Neurobiology. e12792. PMID 35064600 DOI: 10.1111/nan.12792 |
0.307 |
|
| 2021 |
Shi Y, Zhang W, Yang Y, Murzin AG, Falcon B, Kotecha A, van Beers M, Tarutani A, Kametani F, Garringer HJ, Vidal R, Hallinan GI, Lashley T, Saito Y, Murayama S, ... ... Goedert M, et al. Structure-based classification of tauopathies. Nature. PMID 34588692 DOI: 10.1038/s41586-021-03911-7 |
0.353 |
|
| 2021 |
McMurray L, Macdonald JA, Ramakrishnan NK, Zhao Y, Williamson DW, Tietz O, Zhou X, Kealey S, Fagan SG, Smolek T, Cubinkova V, Žilka N, Spillantini MG, Tolkovsky AM, Goedert M, et al. Synthesis and Assessment of Novel Probes for Imaging Tau Pathology in Transgenic Mouse and Rat Models. Acs Chemical Neuroscience. PMID 33689290 DOI: 10.1021/acschemneuro.0c00790 |
0.32 |
|
| 2021 |
Goedert M, Spillantini MG, Falcon B, Zhang W, Newell KL, Hasegawa M, Scheres SHW, Ghetti B. Tau Protein and Frontotemporal Dementias. Advances in Experimental Medicine and Biology. 1281: 177-199. PMID 33433876 DOI: 10.1007/978-3-030-51140-1_12 |
0.372 |
|
| 2020 |
Masuda-Suzukake M, Suzuki G, Hosokawa M, Nonaka T, Goedert M, Hasegawa M. Dextran sulphate-induced tau assemblies cause endogenous tau aggregation and propagation in wild-type mice. Brain Communications. 2: fcaa091. PMID 33005889 DOI: 10.1093/braincomms/fcaa091 |
0.355 |
|
| 2020 |
Goedert M. Tau proteinopathies and the prion concept. Progress in Molecular Biology and Translational Science. 175: 239-259. PMID 32958235 DOI: 10.1016/bs.pmbts.2020.08.003 |
0.353 |
|
| 2020 |
Scheres SH, Zhang W, Falcon B, Goedert M. Cryo-EM structures of tau filaments. Current Opinion in Structural Biology. 64: 17-25. PMID 32603876 DOI: 10.1016/J.Sbi.2020.05.011 |
0.46 |
|
| 2020 |
Schweighauser M, Shi Y, Tarutani A, Kametani F, Murzin AG, Ghetti B, Matsubara T, Tomita T, Ando T, Hasegawa K, Murayama S, Yoshida M, Hasegawa M, Scheres SHW, Goedert M. Structures of α-synuclein filaments from multiple system atrophy. Nature. PMID 32461689 DOI: 10.1038/S41586-020-2317-6 |
0.387 |
|
| 2020 |
Zhang W, Tarutani A, Newell KL, Murzin AG, Matsubara T, Falcon B, Vidal R, Garringer HJ, Shi Y, Ikeuchi T, Murayama S, Ghetti B, Hasegawa M, Goedert M, Scheres SHW. Novel tau filament fold in corticobasal degeneration. Nature. PMID 32050258 DOI: 10.1038/S41586-020-2043-0 |
0.359 |
|
| 2019 |
Goedert M, Spillantini MG. Ordered Assembly of Tau Protein and Neurodegeneration. Advances in Experimental Medicine and Biology. 1184: 3-21. PMID 32096024 DOI: 10.1007/978-981-32-9358-8_1 |
0.343 |
|
| 2019 |
Klingstedt T, Ghetti B, Holton JL, Ling H, Nilsson KPR, Goedert M. Luminescent conjugated oligothiophenes distinguish between α-synuclein assemblies of Parkinson's disease and multiple system atrophy. Acta Neuropathologica Communications. 7: 193. PMID 31796099 DOI: 10.1186/S40478-019-0840-1 |
0.372 |
|
| 2019 |
Lavenir I, Passarella D, Masuda-Suzukake M, Curry A, Holton JL, Ghetti B, Goedert M. Silver staining (Campbell-Switzer) of neuronal α-synuclein assemblies induced by multiple system atrophy and Parkinson's disease brain extracts in transgenic mice. Acta Neuropathologica Communications. 7: 148. PMID 31522685 DOI: 10.1186/S40478-019-0804-5 |
0.32 |
|
| 2019 |
Skachokova Z, Martinisi A, Flach M, Sprenger F, Naegelin Y, Steiner-Monard V, Sollberger M, Monsch AU, Goedert M, Tolnay M, Winkler DT. Cerebrospinal fluid from Alzheimer's disease patients promotes tau aggregation in transgenic mice. Acta Neuropathologica Communications. 7: 72. PMID 31064413 DOI: 10.1186/s40478-019-0725-3 |
0.321 |
|
| 2019 |
Malcolm JC, Breuillaud L, Do Carmo S, Hall H, Welikovitch LA, Macdonald JA, Goedert M, Cuello AC. Neuropathological changes and cognitive deficits in rats transgenic for human mutant tau recapitulate human tauopathy. Neurobiology of Disease. PMID 30905766 DOI: 10.1016/J.Nbd.2019.03.018 |
0.329 |
|
| 2019 |
Falcon B, Zivanov J, Zhang W, Murzin AG, Garringer HJ, Vidal R, Crowther RA, Newell KL, Ghetti B, Goedert M, Scheres SHW. Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules. Nature. PMID 30894745 DOI: 10.1038/S41586-019-1026-5 |
0.476 |
|
| 2019 |
Goedert M, Falcon B, Zhang W, Ghetti B, Scheres SHW. Distinct Conformers of Assembled Tau in Alzheimer's and Pick's Diseases. Cold Spring Harbor Symposia On Quantitative Biology. PMID 30886056 DOI: 10.1101/Sqb.2018.83.037580 |
0.396 |
|
| 2019 |
Macdonald JA, Bronner IF, Drynan L, Fan J, Curry A, Fraser G, Lavenir I, Goedert M. Assembly of transgenic human P301S Tau is necessary for neurodegeneration in murine spinal cord. Acta Neuropathologica Communications. 7: 44. PMID 30885267 DOI: 10.1186/s40478-019-0695-5 |
0.34 |
|
| 2019 |
Zhang W, Falcon B, Murzin AG, Fan J, Crowther RA, Goedert M, Scheres SH. Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases. Elife. 8. PMID 30720432 DOI: 10.2210/Pdb6Qjq/Pdb |
0.46 |
|
| 2018 |
Falcon B, Zhang W, Schweighauser M, Murzin AG, Vidal R, Garringer HJ, Ghetti B, Scheres SHW, Goedert M. Tau filaments from multiple cases of sporadic and inherited Alzheimer's disease adopt a common fold. Acta Neuropathologica. PMID 30276465 DOI: 10.1007/S00401-018-1914-Z |
0.405 |
|
| 2018 |
Passarella D, Goedert M. Beta-sheet assembly of Tau and neurodegeneration in Drosophila melanogaster. Neurobiology of Aging. 72: 98-105. PMID 30240946 DOI: 10.1016/j.neurobiolaging.2018.07.022 |
0.34 |
|
| 2018 |
Götz J, Bodea LG, Goedert M. Rodent models for Alzheimer disease. Nature Reviews. Neuroscience. PMID 30194347 DOI: 10.1038/S41583-018-0054-8 |
0.304 |
|
| 2018 |
Falcon B, Zhang W, Murzin AG, Murshudov G, Garringer HJ, Vidal R, Crowther RA, Ghetti B, Scheres SHW, Goedert M. Structures of filaments from Pick's disease reveal a novel tau protein fold. Nature. PMID 30158706 DOI: 10.1038/S41586-018-0454-Y |
0.472 |
|
| 2018 |
Brelstaff J, Tolkovsky AM, Ghetti B, Goedert M, Spillantini MG. Living Neurons with Tau Filaments Aberrantly Expose Phosphatidylserine and Are Phagocytosed by Microglia. Cell Reports. 24: 1939-1948.e4. PMID 30134156 DOI: 10.1016/J.Celrep.2018.07.072 |
0.426 |
|
| 2018 |
Mund T, Masuda-Suzukake M, Goedert M, Pelham HR. Ubiquitination of alpha-synuclein filaments by Nedd4 ligases. Plos One. 13: e0200763. PMID 30021006 DOI: 10.1371/Journal.Pone.0200763 |
0.309 |
|
| 2018 |
Goedert M. Tau filaments in neurodegenerative diseases. Febs Letters. PMID 29790176 DOI: 10.1002/1873-3468.13108 |
0.393 |
|
| 2018 |
Kundel F, Hong L, Falcon B, McEwan W, Michaels TCT, Meisl G, Esteras N, Abramov AY, Knowles TPJ, Goedert M, Klenerman D. Measurement of tau filament fragmentation provides insights into prion-like spreading. Acs Chemical Neuroscience. PMID 29590529 DOI: 10.1021/Acschemneuro.8B00094 |
0.441 |
|
| 2018 |
Goedert M, Yamaguchi Y, Mishra SK, Higuchi M, Sahara N. Tau Filaments and the Development of Positron Emission Tomography Tracers. Frontiers in Neurology. 9: 70. PMID 29497399 DOI: 10.3389/Fneur.2018.00070 |
0.455 |
|
| 2017 |
Falcon B, Noad J, McMahon H, Randow F, Goedert M. Galectin-8-mediated selective autophagy protects against seeded tau aggregation. The Journal of Biological Chemistry. PMID 29282296 DOI: 10.1074/Jbc.M117.809293 |
0.421 |
|
| 2017 |
Mudher A, Colin M, Dujardin S, Medina M, Dewachter I, Naini SMA, Mandelkow EM, Mandelkow E, Buée L, Goedert M, Brion JP. What is the evidence that tau pathology spreads through prion-like propagation? Acta Neuropathologica Communications. 5: 99. PMID 29258615 DOI: 10.1186/S40478-017-0488-7 |
0.341 |
|
| 2017 |
Goedert M, Eisenberg DS, Crowther RA. Propagation of Tau Aggregates and Neurodegeneration. Annual Review of Neuroscience. 40: 189-210. PMID 28772101 DOI: 10.1146/annurev-neuro-072116-031153 |
0.338 |
|
| 2017 |
Fitzpatrick AWP, Falcon B, He S, Murzin AG, Murshudov G, Garringer HJ, Crowther RA, Ghetti B, Goedert M, Scheres SHW. Cryo-EM structures of tau filaments from Alzheimer's disease. Nature. PMID 28678775 DOI: 10.1038/Nature23002 |
0.451 |
|
| 2017 |
Goedert M, Spillantini MG. Propagation of Tau aggregates. Molecular Brain. 10: 18. PMID 28558799 DOI: 10.1186/S13041-017-0298-7 |
0.444 |
|
| 2017 |
Goedert M, Jakes R, Spillantini MG. The Synucleinopathies: Twenty Years On. Journal of Parkinson's Disease. 7: S53-S71. PMID 28282814 DOI: 10.3233/Jpd-179005 |
0.316 |
|
| 2017 |
McEwan WA, Falcon B, Vaysburd M, Clift D, Oblak AL, Ghetti B, Goedert M, James LC. Cytosolic Fc receptor TRIM21 inhibits seeded tau aggregation. Proceedings of the National Academy of Sciences of the United States of America. PMID 28049840 DOI: 10.1073/Pnas.1607215114 |
0.442 |
|
| 2016 |
Clavaguera F, Tolnay M, Goedert M. The Prion-Like Behavior of Assembled Tau in Transgenic Mice. Cold Spring Harbor Perspectives in Medicine. PMID 27940600 DOI: 10.1101/cshperspect.a024372 |
0.361 |
|
| 2016 |
Goedert M. The ordered assembly of tau is the gain-of-toxic function that causes human tauopathies. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27686274 DOI: 10.1016/j.jalz.2016.09.001 |
0.324 |
|
| 2016 |
Goedert M, Masuda-Suzukake M, Falcon B. Like prions: the propagation of aggregated tau and α-synuclein in neurodegeneration. Brain : a Journal of Neurology. PMID 27658420 DOI: 10.1093/Brain/Aww230 |
0.389 |
|
| 2016 |
Jackson SJ, Kerridge C, Cooper J, Cavallini A, Falcon B, Cella CV, Landi A, Szekeres PG, Murray TK, Ahmed Z, Goedert M, Hutton M, O'Neill MJ, Bose S. Short Fibrils Constitute the Major Species of Seed-Competent Tau in the Brains of Mice Transgenic for Human P301S Tau. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 762-72. PMID 26791207 DOI: 10.1523/Jneurosci.3542-15.2016 |
0.432 |
|
| 2015 |
Goedert M, Spillantini MG, Crowther RA. A Brief History of Tau. Clinical Chemistry. 61: 1417-8. PMID 26330509 DOI: 10.1373/Clinchem.2015.245142 |
0.321 |
|
| 2015 |
Goedert M. NEURODEGENERATION. Alzheimer's and Parkinson's diseases: The prion concept in relation to assembled Aβ, tau, and α-synuclein. Science (New York, N.Y.). 349: 1255555. PMID 26250687 DOI: 10.1126/science.1255555 |
0.332 |
|
| 2015 |
Brelstaff J, Ossola B, Neher JJ, Klingstedt T, Nilsson KP, Goedert M, Spillantini MG, Tolkovsky AM. The fluorescent pentameric oligothiophene pFTAA identifies filamentous tau in live neurons cultured from adult P301S tau mice. Frontiers in Neuroscience. 9: 184. PMID 26074756 DOI: 10.3389/Fnins.2015.00184 |
0.318 |
|
| 2015 |
Duyckaerts C, Braak H, Brion JP, Buée L, Del Tredici K, Goedert M, Halliday G, Neumann M, Spillantini MG, Tolnay M, Uchihara T. PART is part of Alzheimer disease. Acta Neuropathologica. 129: 749-56. PMID 25628035 DOI: 10.1007/S00401-015-1390-7 |
0.39 |
|
| 2015 |
Ghetti B, Oblak AL, Boeve BF, Johnson KA, Dickerson BC, Goedert M. Invited review: Frontotemporal dementia caused by microtubule-associated protein tau gene (MAPT) mutations: a chameleon for neuropathology and neuroimaging. Neuropathology and Applied Neurobiology. 41: 24-46. PMID 25556536 DOI: 10.1111/Nan.12213 |
0.436 |
|
| 2015 |
Falcon B, Cavallini A, Angers R, Glover S, Murray TK, Barnham L, Jackson S, O'Neill MJ, Isaacs AM, Hutton ML, Szekeres PG, Goedert M, Bose S. Conformation determines the seeding potencies of native and recombinant Tau aggregates. The Journal of Biological Chemistry. 290: 1049-65. PMID 25406315 DOI: 10.1074/Jbc.M114.589309 |
0.458 |
|
| 2015 |
Clavaguera F, Hench J, Goedert M, Tolnay M. Invited review: Prion-like transmission and spreading of tau pathology. Neuropathology and Applied Neurobiology. 41: 47-58. PMID 25399729 DOI: 10.1111/nan.12197 |
0.378 |
|
| 2014 |
Xu H, Rösler TW, Carlsson T, de Andrade A, Fiala O, Hollerhage M, Oertel WH, Goedert M, Aigner A, Höglinger GU. Tau silencing by siRNA in the P301S mouse model of tauopathy. Current Gene Therapy. 14: 343-51. PMID 25687501 DOI: 10.2174/156652321405140926160602 |
0.388 |
|
| 2014 |
Höllerhage M, Deck R, De Andrade A, Respondek G, Xu H, Rösler TW, Salama M, Carlsson T, Yamada ES, Gad El Hak SA, Goedert M, Oertel WH, Höglinger GU. Piericidin A aggravates Tau pathology in P301S transgenic mice. Plos One. 9: e113557. PMID 25437199 DOI: 10.1371/Journal.Pone.0113557 |
0.364 |
|
| 2014 |
Goedert M, Falcon B, Clavaguera F, Tolnay M. Prion-like mechanisms in the pathogenesis of tauopathies and synucleinopathies. Current Neurology and Neuroscience Reports. 14: 495. PMID 25218483 DOI: 10.1007/S11910-014-0495-Z |
0.415 |
|
| 2014 |
Flach K, Ramminger E, Hilbrich I, Arsalan-Werner A, Albrecht F, Herrmann L, Goedert M, Arendt T, Holzer M. Axotrophin/MARCH7 acts as an E3 ubiquitin ligase and ubiquitinates tau protein in vitro impairing microtubule binding. Biochimica Et Biophysica Acta. 1842: 1527-38. PMID 24905733 DOI: 10.1016/J.Bbadis.2014.05.029 |
0.452 |
|
| 2014 |
Herva ME, Zibaee S, Fraser G, Barker RA, Goedert M, Spillantini MG. Anti-amyloid compounds inhibit α-synuclein aggregation induced by protein misfolding cyclic amplification (PMCA). The Journal of Biological Chemistry. 289: 11897-905. PMID 24584936 DOI: 10.1074/Jbc.M113.542340 |
0.32 |
|
| 2014 |
Ahmed Z, Cooper J, Murray TK, Garn K, McNaughton E, Clarke H, Parhizkar S, Ward MA, Cavallini A, Jackson S, Bose S, Clavaguera F, Tolnay M, Lavenir I, Goedert M, et al. A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity. Acta Neuropathologica. 127: 667-83. PMID 24531916 DOI: 10.1007/S00401-014-1254-6 |
0.48 |
|
| 2014 |
Clavaguera F, Hench J, Lavenir I, Schweighauser G, Frank S, Goedert M, Tolnay M. Peripheral administration of tau aggregates triggers intracerebral tauopathy in transgenic mice. Acta Neuropathologica. 127: 299-301. PMID 24362441 DOI: 10.1007/S00401-013-1231-5 |
0.402 |
|
| 2014 |
Iovino M, Pfisterer U, Holton JL, Lashley T, Swingler RJ, Calo L, Treacy R, Revesz T, Parmar M, Goedert M, Muqit MM, Spillantini MG. The novel MAPT mutation K298E: mechanisms of mutant tau toxicity, brain pathology and tau expression in induced fibroblast-derived neurons. Acta Neuropathologica. 127: 283-95. PMID 24292008 DOI: 10.1007/S00401-013-1219-1 |
0.413 |
|
| 2013 |
Hoffmann NA, Dorostkar MM, Blumenstock S, Goedert M, Herms J. Impaired plasticity of cortical dendritic spines in P301S tau transgenic mice. Acta Neuropathologica Communications. 1: 82. PMID 24344647 DOI: 10.1186/2051-5960-1-82 |
0.411 |
|
| 2013 |
Mellone M, Kestoras D, Andrews MR, Dassie E, Crowther RA, Stokin GB, Tinsley J, Horne G, Goedert M, Tolkovsky AM, Spillantini MG. Tau pathology is present in vivo and develops in vitro in sensory neurons from human P301S tau transgenic mice: a system for screening drugs against tauopathies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 18175-89. PMID 24227726 DOI: 10.1523/Jneurosci.4933-12.2013 |
0.422 |
|
| 2013 |
Hastings MH, Goedert M. Circadian clocks and neurodegenerative diseases: time to aggregate? Current Opinion in Neurobiology. 23: 880-7. PMID 23797088 DOI: 10.1016/J.Conb.2013.05.004 |
0.31 |
|
| 2013 |
Klingstedt T, Shirani H, Ã…slund KO, Cairns NJ, Sigurdson CJ, Goedert M, Nilsson KP. The structural basis for optimal performance of oligothiophene-based fluorescent amyloid ligands: conformational flexibility is essential for spectral assignment of a diversity of protein aggregates. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 10179-92. PMID 23780508 DOI: 10.1002/Chem.201301463 |
0.338 |
|
| 2013 |
Clavaguera F, Akatsu H, Fraser G, Crowther RA, Frank S, Hench J, Probst A, Winkler DT, Reichwald J, Staufenbiel M, Ghetti B, Goedert M, Tolnay M. Brain homogenates from human tauopathies induce tau inclusions in mouse brain. Proceedings of the National Academy of Sciences of the United States of America. 110: 9535-40. PMID 23690619 DOI: 10.1073/Pnas.1301175110 |
0.442 |
|
| 2013 |
Spillantini MG, Goedert M. Tau pathology and neurodegeneration. The Lancet. Neurology. 12: 609-22. PMID 23684085 DOI: 10.1016/S1474-4422(13)70090-5 |
0.49 |
|
| 2013 |
Ozcelik S, Fraser G, Castets P, Schaeffer V, Skachokova Z, Breu K, Clavaguera F, Sinnreich M, Kappos L, Goedert M, Tolnay M, Winkler DT. Rapamycin attenuates the progression of tau pathology in P301S tau transgenic mice. Plos One. 8: e62459. PMID 23667480 DOI: 10.1371/Journal.Pone.0062459 |
0.428 |
|
| 2013 |
Clavaguera F, Lavenir I, Falcon B, Frank S, Goedert M, Tolnay M. "Prion-like" templated misfolding in tauopathies. Brain Pathology (Zurich, Switzerland). 23: 342-9. PMID 23587140 DOI: 10.1111/Bpa.12044 |
0.479 |
|
| 2013 |
Goedert M, Spillantini MG, Del Tredici K, Braak H. 100 years of Lewy pathology. Nature Reviews. Neurology. 9: 13-24. PMID 23183883 DOI: 10.1038/Nrneurol.2012.242 |
0.331 |
|
| 2012 |
Schön C, Hoffmann NA, Ochs SM, Burgold S, Filser S, Steinbach S, Seeliger MW, Arzberger T, Goedert M, Kretzschmar HA, Schmidt B, Herms J. Long-term in vivo imaging of fibrillar tau in the retina of P301S transgenic mice. Plos One. 7: e53547. PMID 23300938 DOI: 10.1371/Journal.Pone.0053547 |
0.466 |
|
| 2012 |
Schaeffer V, Goedert M. Stimulation of autophagy is neuroprotective in a mouse model of human tauopathy. Autophagy. 8: 1686-7. PMID 22874558 DOI: 10.4161/Auto.21488 |
0.429 |
|
| 2012 |
Schaeffer V, Lavenir I, Ozcelik S, Tolnay M, Winkler DT, Goedert M. Stimulation of autophagy reduces neurodegeneration in a mouse model of human tauopathy. Brain : a Journal of Neurology. 135: 2169-77. PMID 22689910 DOI: 10.1093/Brain/Aws143 |
0.429 |
|
| 2012 |
Bull ND, Guidi A, Goedert M, Martin KR, Spillantini MG. Reduced axonal transport and increased excitotoxic retinal ganglion cell degeneration in mice transgenic for human mutant P301S tau. Plos One. 7: e34724. PMID 22496848 DOI: 10.1371/Journal.Pone.0034724 |
0.321 |
|
| 2012 |
Goedert M, Ghetti B, Spillantini MG. Frontotemporal dementia: implications for understanding Alzheimer disease. Cold Spring Harbor Perspectives in Medicine. 2: a006254. PMID 22355793 DOI: 10.1101/Cshperspect.A006254 |
0.395 |
|
| 2012 |
Yoshida H, Goedert M. Phosphorylation of microtubule-associated protein tau by AMPK-related kinases. Journal of Neurochemistry. 120: 165-76. PMID 21985311 DOI: 10.1111/J.1471-4159.2011.07523.X |
0.417 |
|
| 2012 |
Goedert M, Spillantini MG. Synucleinopathies and Tauopathies Basic Neurochemistry. 829-843. DOI: 10.1016/B978-0-12-374947-5.00047-X |
0.312 |
|
| 2011 |
Goedert M, Spillantini MG. Pathogenesis of the tauopathies. Journal of Molecular Neuroscience : Mn. 45: 425-31. PMID 21785996 DOI: 10.1007/S12031-011-9593-4 |
0.488 |
|
| 2011 |
Gasparini L, Crowther RA, Martin KR, Berg N, Coleman M, Goedert M, Spillantini MG. Tau inclusions in retinal ganglion cells of human P301S tau transgenic mice: effects on axonal viability. Neurobiology of Aging. 32: 419-33. PMID 19356824 DOI: 10.1016/J.Neurobiolaging.2009.03.002 |
0.391 |
|
| 2011 |
Ghetti B, Wszolek ZK, Boeve BF, Spina S, Goedert M. Frontotemporal Dementia and Parkinsonism Linked to Chromosome 17 Neurodegeneration: the Molecular Pathology of Dementia and Movement Disorders: Second Edition. 110-134. DOI: 10.1002/9781444341256.Ch14 |
0.441 |
|
| 2010 |
Zibaee S, Fraser G, Jakes R, Owen D, Serpell LC, Crowther RA, Goedert M. Human beta-synuclein rendered fibrillogenic by designed mutations. The Journal of Biological Chemistry. 285: 38555-67. PMID 20833719 DOI: 10.1074/Jbc.M110.160721 |
0.337 |
|
| 2010 |
Hampton DW, Webber DJ, Bilican B, Goedert M, Spillantini MG, Chandran S. Cell-mediated neuroprotection in a mouse model of human tauopathy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 9973-83. PMID 20668182 DOI: 10.1523/Jneurosci.0834-10.2010 |
0.466 |
|
| 2010 |
Garcia-Reitböck P, Anichtchik O, Bellucci A, Iovino M, Ballini C, Fineberg E, Ghetti B, Della Corte L, Spano P, Tofaris GK, Goedert M, Spillantini MG. SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson's disease. Brain : a Journal of Neurology. 133: 2032-44. PMID 20534649 DOI: 10.1093/Brain/Awq132 |
0.351 |
|
| 2010 |
Goedert M, Clavaguera F, Tolnay M. The propagation of prion-like protein inclusions in neurodegenerative diseases. Trends in Neurosciences. 33: 317-25. PMID 20493564 DOI: 10.1016/J.Tins.2010.04.003 |
0.419 |
|
| 2010 |
Coomaraswamy J, Kilger E, Wölfing H, Schäfer C, Kaeser SA, Wegenast-Braun BM, Hefendehl JK, Wolburg H, Mazzella M, Ghiso J, Goedert M, Akiyama H, Garcia-Sierra F, Wolfer DP, Mathews PM, et al. Modeling familial Danish dementia in mice supports the concept of the amyloid hypothesis of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 107: 7969-74. PMID 20385796 DOI: 10.1073/Pnas.1001056107 |
0.383 |
|
| 2010 |
Clavaguera F, Goedert M, Tolnay M. [Induction and spreading of tau pathology in a mouse model of Alzheimer's disease]. Mã©Decine Sciences : M/S. 26: 121-4. PMID 20188034 DOI: 10.1051/medsci/2010262121 |
0.318 |
|
| 2010 |
Chambraud B, Sardin E, Giustiniani J, Dounane O, Schumacher M, Goedert M, Baulieu EE. A role for FKBP52 in Tau protein function. Proceedings of the National Academy of Sciences of the United States of America. 107: 2658-63. PMID 20133804 DOI: 10.1073/Pnas.0914957107 |
0.495 |
|
| 2010 |
Scattoni ML, Gasparini L, Alleva E, Goedert M, Calamandrei G, Spillantini MG. Early behavioural markers of disease in P301S tau transgenic mice. Behavioural Brain Research. 208: 250-7. PMID 20004218 DOI: 10.1016/J.Bbr.2009.12.002 |
0.346 |
|
| 2009 |
Yamashita M, Nonaka T, Arai T, Kametani F, Buchman VL, Ninkina N, Bachurin SO, Akiyama H, Goedert M, Hasegawa M. Methylene blue and dimebon inhibit aggregation of TDP-43 in cellular models. Febs Letters. 583: 2419-24. PMID 19560462 DOI: 10.1016/J.Febslet.2009.06.042 |
0.345 |
|
| 2009 |
Clavaguera F, Bolmont T, Crowther RA, Abramowski D, Frank S, Probst A, Fraser G, Stalder AK, Beibel M, Staufenbiel M, Jucker M, Goedert M, Tolnay M. Transmission and spreading of tauopathy in transgenic mouse brain. Nature Cell Biology. 11: 909-13. PMID 19503072 DOI: 10.1038/Ncb1901 |
0.5 |
|
| 2009 |
Goedert M. Oskar Fischer and the study of dementia. Brain : a Journal of Neurology. 132: 1102-11. PMID 18952676 DOI: 10.1093/Brain/Awn256 |
0.363 |
|
| 2008 |
Kovacs GG, Majtenyi K, Spina S, Murrell JR, Gelpi E, Hoftberger R, Fraser G, Crowther RA, Goedert M, Budka H, Ghetti B. White matter tauopathy with globular glial inclusions: a distinct sporadic frontotemporal lobar degeneration. Journal of Neuropathology and Experimental Neurology. 67: 963-75. PMID 18800011 DOI: 10.1097/Nen.0B013E318187A80F |
0.41 |
|
| 2008 |
Velasco A, Fraser G, Delobel P, Ghetti B, Lavenir I, Goedert M. Detection of filamentous tau inclusions by the fluorescent Congo red derivative FSB [(trans,trans)-1-fluoro-2,5-bis(3-hydroxycarbonyl-4-hydroxy)styrylbenzene]. Febs Letters. 582: 901-6. PMID 18291106 DOI: 10.1016/J.Febslet.2008.02.025 |
0.455 |
|
| 2008 |
Radde R, Duma C, Goedert M, Jucker M. The value of incomplete mouse models of Alzheimer's disease. European Journal of Nuclear Medicine and Molecular Imaging. 35: S70-4. PMID 18270700 DOI: 10.1007/S00259-007-0704-Y |
0.379 |
|
| 2008 |
Delobel P, Lavenir I, Fraser G, Ingram E, Holzer M, Ghetti B, Spillantini MG, Crowther RA, Goedert M. Analysis of tau phosphorylation and truncation in a mouse model of human tauopathy. The American Journal of Pathology. 172: 123-31. PMID 18079436 DOI: 10.2353/Ajpath.2008.070627 |
0.473 |
|
| 2008 |
Spina S, Farlow MR, Unverzagt FW, Kareken DA, Murrell JR, Fraser G, Epperson F, Crowther RA, Spillantini MG, Goedert M, Ghetti B. The tauopathy associated with mutation +3 in intron 10 of Tau: characterization of the MSTD family. Brain : a Journal of Neurology. 131: 72-89. PMID 18065436 DOI: 10.1093/Brain/Awm280 |
0.407 |
|
| 2007 |
Magnani E, Fan J, Gasparini L, Golding M, Williams M, Schiavo G, Goedert M, Amos LA, Spillantini MG. Interaction of tau protein with the dynactin complex. The Embo Journal. 26: 4546-54. PMID 17932487 DOI: 10.1038/Sj.Emboj.7601878 |
0.452 |
|
| 2007 |
Virdee K, Yoshida H, Peak-Chew S, Goedert M. Phosphorylation of human microtubule-associated protein tau by protein kinases of the AGC subfamily. Febs Letters. 581: 2657-62. PMID 17512525 DOI: 10.1016/J.Febslet.2007.05.009 |
0.409 |
|
| 2007 |
Goedert M, Ghetti B. Alois Alzheimer: his life and times. Brain Pathology (Zurich, Switzerland). 17: 57-62. PMID 17493039 DOI: 10.1111/J.1750-3639.2007.00056.X |
0.321 |
|
| 2007 |
Spina S, Murrell JR, Yoshida H, Ghetti B, Bermingham N, Sweeney B, Dlouhy SR, Crowther RA, Goedert M, Keohane C. The novel Tau mutation G335S: clinical, neuropathological and molecular characterization. Acta Neuropathologica. 113: 461-70. PMID 17186252 DOI: 10.1007/S00401-006-0182-5 |
0.46 |
|
| 2007 |
Ghetti B, Goedert M. Symposium: Tau protein and neurodegeneration Brain Pathology. 17: 56. DOI: 10.1111/j.1750-3639.2007.00057.x |
0.306 |
|
| 2007 |
Goedert M, Spillantini MG. Chapter 4 Tau Protein and the Dementias Blue Books of Neurology. 30: 88-111. DOI: 10.1016/S1877-184X(09)70055-3 |
0.301 |
|
| 2006 |
Goedert M, Spillantini MG. A century of Alzheimer's disease. Science (New York, N.Y.). 314: 777-81. PMID 17082447 DOI: 10.1126/Science.1132814 |
0.447 |
|
| 2006 |
Goedert M, Spillantini MG. Frontotemporal lobar degeneration through loss of progranulin function. Brain : a Journal of Neurology. 129: 2808-10. PMID 17071919 DOI: 10.1093/Brain/Awl291 |
0.372 |
|
| 2006 |
Yoshida H, Goedert M. Sequential phosphorylation of tau protein by cAMP-dependent protein kinase and SAPK4/p38delta or JNK2 in the presence of heparin generates the AT100 epitope. Journal of Neurochemistry. 99: 154-64. PMID 16987243 DOI: 10.1111/j.1471-4159.2006.04052.x |
0.373 |
|
| 2006 |
Spillantini MG, Murrell JR, Goedert M, Farlow M, Klug A, Ghetti B. Mutations in the tau gene (MAPT) in FTDP-17: the family with Multiple System Tauopathy with Presenile Dementia (MSTD). Journal of Alzheimer's Disease : Jad. 9: 373-80. PMID 16914875 DOI: 10.3233/Jad-2006-9S342 |
0.436 |
|
| 2006 |
Goedert M, Klug A, Crowther RA. Tau protein, the paired helical filament and Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 9: 195-207. PMID 16914859 DOI: 10.3233/Jad-2006-9S323 |
0.475 |
|
| 2006 |
Tofaris GK, Garcia Reitböck P, Humby T, Lambourne SL, O'Connell M, Ghetti B, Gossage H, Emson PC, Wilkinson LS, Goedert M, Spillantini MG. Pathological changes in dopaminergic nerve cells of the substantia nigra and olfactory bulb in mice transgenic for truncated human alpha-synuclein(1-120): implications for Lewy body disorders. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 3942-50. PMID 16611810 DOI: 10.1523/Jneurosci.4965-05.2006 |
0.511 |
|
| 2006 |
Delobel P, Lavenir I, Ghetti B, Holzer M, Goedert M. Cell-cycle markers in a transgenic mouse model of human tauopathy: increased levels of cyclin-dependent kinase inhibitors p21Cip1 and p27Kip1. The American Journal of Pathology. 168: 878-87. PMID 16507903 DOI: 10.2353/Ajpath.2006.050540 |
0.446 |
|
| 2006 |
Yoshida H, Craxton M, Jakes R, Zibaee S, Tavaré R, Fraser G, Serpell LC, Davletov B, Crowther RA, Goedert M. Synuclein proteins of the pufferfish Fugu rubripes: sequences and functional characterization. Biochemistry. 45: 2599-607. PMID 16489753 DOI: 10.1021/Bi051993M |
0.344 |
|
| 2006 |
Gasparini L, Goedert M, Spillantini MG. P1-086: Hyperphosphorylated tau accumulates in retinal ganglion neurons of P301S tau transgenic mice Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.461 |
0.346 |
|
| 2005 |
Goedert M. Tau gene mutations and their effects. Movement Disorders : Official Journal of the Movement Disorder Society. 20: S45-52. PMID 16092090 DOI: 10.1002/Mds.20539 |
0.486 |
|
| 2005 |
Yamaguchi K, Cochran EJ, Murrell JR, Polymeropoulos MH, Shannon KM, Crowther RA, Goedert M, Ghetti B. Abundant neuritic inclusions and microvacuolar changes in a case of diffuse Lewy body disease with the A53T mutation in the alpha-synuclein gene. Acta Neuropathologica. 110: 298-305. PMID 15981014 DOI: 10.1007/S00401-005-1042-4 |
0.323 |
|
| 2005 |
Feijoo C, Campbell DG, Jakes R, Goedert M, Cuenda A. Evidence that phosphorylation of the microtubule-associated protein Tau by SAPK4/p38delta at Thr50 promotes microtubule assembly. Journal of Cell Science. 118: 397-408. PMID 15632108 DOI: 10.1242/jcs.01655 |
0.373 |
|
| 2005 |
Goedert M, Jakes R. Mutations causing neurodegenerative tauopathies. Biochimica Et Biophysica Acta. 1739: 240-50. PMID 15615642 DOI: 10.1016/J.Bbadis.2004.08.007 |
0.491 |
|
| 2005 |
Taniguchi S, Suzuki N, Masuda M, Hisanaga S, Iwatsubo T, Goedert M, Hasegawa M. Inhibition of heparin-induced tau filament formation by phenothiazines, polyphenols, and porphyrins. The Journal of Biological Chemistry. 280: 7614-23. PMID 15611092 DOI: 10.1074/Jbc.M408714200 |
0.441 |
|
| 2004 |
Bellucci A, Westwood AJ, Ingram E, Casamenti F, Goedert M, Spillantini MG. Induction of inflammatory mediators and microglial activation in mice transgenic for mutant human P301S tau protein. The American Journal of Pathology. 165: 1643-52. PMID 15509534 DOI: 10.1016/S0002-9440(10)63421-9 |
0.378 |
|
| 2004 |
Holzer M, Craxton M, Jakes R, Arendt T, Goedert M. Tau gene (MAPT) sequence variation among primates. Gene. 341: 313-22. PMID 15474313 DOI: 10.1016/J.Gene.2004.07.013 |
0.432 |
|
| 2004 |
Yoshida H, Hastie CJ, McLauchlan H, Cohen P, Goedert M. Phosphorylation of microtubule-associated protein tau by isoforms of c-Jun N-terminal kinase (JNK). Journal of Neurochemistry. 90: 352-8. PMID 15228592 DOI: 10.1111/J.1471-4159.2004.02479.X |
0.442 |
|
| 2004 |
Takao M, Ghetti B, Yoshida H, Piccardo P, Narain Y, Murrell JR, Vidal R, Glazier BS, Jakes R, Tsutsui M, Spillantini MG, Crowther RA, Goedert M, Koto A. Early-onset dementia with Lewy bodies. Brain Pathology (Zurich, Switzerland). 14: 137-47. PMID 15193026 DOI: 10.1111/J.1750-3639.2004.Tb00046.X |
0.372 |
|
| 2004 |
Goedert M. Tau protein and neurodegeneration. Seminars in Cell & Developmental Biology. 15: 45-9. PMID 15036206 DOI: 10.1016/J.Semcdb.2003.12.015 |
0.477 |
|
| 2004 |
Sabio G, Reuver S, Feijoo C, Hasegawa M, Thomas GM, Centeno F, Kuhlendahl S, Leal-Ortiz S, Goedert M, Garner C, Cuenda A. Stress- and mitogen-induced phosphorylation of the synapse-associated protein SAP90/PSD-95 by activation of SAPK3/p38gamma and ERK1/ERK2. The Biochemical Journal. 380: 19-30. PMID 14741046 DOI: 10.1042/Bj20031628 |
0.334 |
|
| 2003 |
van Herpen E, Rosso SM, Serverijnen LA, Yoshida H, Breedveld G, van de Graaf R, Kamphorst W, Ravid R, Willemsen R, Dooijes D, Majoor-Krakauer D, Kros JM, Crowther RA, Goedert M, Heutink P, et al. Variable phenotypic expression and extensive tau pathology in two families with the novel tau mutation L315R. Annals of Neurology. 54: 573-81. PMID 14595646 DOI: 10.1002/Ana.10721 |
0.467 |
|
| 2003 |
Goedert M. Neurodegenerative tauopathy in the worm. Proceedings of the National Academy of Sciences of the United States of America. 100: 9653-5. PMID 12913116 DOI: 10.1073/Pnas.1834191100 |
0.504 |
|
| 2003 |
Berriman J, Serpell LC, Oberg KA, Fink AL, Goedert M, Crowther RA. Tau filaments from human brain and from in vitro assembly of recombinant protein show cross-beta structure. Proceedings of the National Academy of Sciences of the United States of America. 100: 9034-8. PMID 12853572 DOI: 10.1073/Pnas.1530287100 |
0.307 |
|
| 2003 |
Kar S, Fan J, Smith MJ, Goedert M, Amos LA. Repeat motifs of tau bind to the insides of microtubules in the absence of taxol. The Embo Journal. 22: 70-7. PMID 12505985 DOI: 10.1093/Emboj/Cdg001 |
0.395 |
|
| 2002 |
Yoshida H, Goedert M. Molecular cloning and functional characterization of chicken brain tau: isoforms with up to five tandem repeats. Biochemistry. 41: 15203-11. PMID 12484758 DOI: 10.1021/Bi026464M |
0.429 |
|
| 2002 |
Allen B, Ingram E, Takao M, Smith MJ, Jakes R, Virdee K, Yoshida H, Holzer M, Craxton M, Emson PC, Atzori C, Migheli A, Crowther RA, Ghetti B, Spillantini MG, ... Goedert M, et al. Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 9340-51. PMID 12417659 DOI: 10.1523/Jneurosci.22-21-09340.2002 |
0.616 |
|
| 2002 |
David DC, Layfield R, Serpell L, Narain Y, Goedert M, Spillantini MG. Proteasomal degradation of tau protein. Journal of Neurochemistry. 83: 176-85. PMID 12358741 DOI: 10.1046/J.1471-4159.2002.01137.X |
0.433 |
|
| 2002 |
Buée-Scherrer V, Goedert M. Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases in intact cells. Febs Letters. 515: 151-4. PMID 11943212 DOI: 10.1016/S0014-5793(02)02460-2 |
0.422 |
|
| 2002 |
Yoshida H, Crowther RA, Goedert M. Functional effects of tau gene mutations deltaN296 and N296H. Journal of Neurochemistry. 80: 548-51. PMID 11906000 DOI: 10.1046/J.0022-3042.2001.00729.X |
0.406 |
|
| 2002 |
Rosso SM, van Herpen E, Deelen W, Kamphorst W, Severijnen LA, Willemsen R, Ravid R, Niermeijer MF, Dooijes D, Smith MJ, Goedert M, Heutink P, van Swieten JC. A novel tau mutation, S320F, causes a tauopathy with inclusions similar to those in Pick's disease. Annals of Neurology. 51: 373-6. PMID 11891833 DOI: 10.1002/Ana.10140 |
0.421 |
|
| 2002 |
Syme CD, Blanch EW, Holt C, Jakes R, Goedert M, Hecht L, Barron LD. A Raman optical activity study of rheomorphism in caseins, synucleins and tau. New insight into the structure and behaviour of natively unfolded proteins. European Journal of Biochemistry / Febs. 269: 148-56. PMID 11784308 DOI: 10.1046/J.0014-2956.2001.02633.X |
0.386 |
|
| 2002 |
Delobel P, Flament S, Hamdane M, Jakes R, Rousseau A, Delacourte A, Vilain JP, Goedert M, Buée L. Functional characterization of FTDP-17 tau gene mutations through their effects on Xenopus oocyte maturation. The Journal of Biological Chemistry. 277: 9199-205. PMID 11756436 DOI: 10.1074/Jbc.M107716200 |
0.428 |
|
| 2001 |
Spillantini MG, Goedert M. Tau and Parkinson disease. Jama. 286: 2324-6. PMID 11710900 DOI: 10.1001/Jama.286.18.2324 |
0.416 |
|
| 2001 |
Neumann M, Schulz-Schaeffer W, Crowther RA, Smith MJ, Spillantini MG, Goedert M, Kretzschmar HA. Pick's disease associated with the novel Tau gene mutation K369I. Annals of Neurology. 50: 503-13. PMID 11601501 DOI: 10.1002/Ana.1223 |
0.489 |
|
| 2001 |
Lee VM, Goedert M, Trojanowski JQ. Neurodegenerative tauopathies. Annual Review of Neuroscience. 24: 1121-59. PMID 11520930 DOI: 10.1146/annurev.neuro.24.1.1121 |
0.375 |
|
| 2001 |
Hartmann AM, Rujescu D, Giannakouros T, Nikolakaki E, Goedert M, Mandelkow EM, Gao QS, Andreadis A, Stamm S. Regulation of alternative splicing of human tau exon 10 by phosphorylation of splicing factors. Molecular and Cellular Neurosciences. 18: 80-90. PMID 11461155 DOI: 10.1006/Mcne.2001.1000 |
0.428 |
|
| 2001 |
Goedert M, Spillantini MG. Tau gene mutations and neurodegeneration. Biochemical Society Symposium. 59-71. PMID 11447840 DOI: 10.1042/Bss0670059 |
0.472 |
|
| 2001 |
Goedert M. Alpha-synuclein and neurodegenerative diseases. Nature Reviews. Neuroscience. 2: 492-501. PMID 11433374 DOI: 10.1038/35081564 |
0.35 |
|
| 2001 |
Spillantini MG, Goedert M. Tau gene mutations and tau pathology in frontotemporal dementia and parkinsonism linked to chromosome 17. Advances in Experimental Medicine and Biology. 487: 21-37. PMID 11403160 DOI: 10.1007/978-1-4615-1249-3_3 |
0.474 |
|
| 2001 |
Goedert M. The significance of tau and alpha-synuclein inclusions in neurodegenerative diseases. Current Opinion in Genetics & Development. 11: 343-51. PMID 11377973 DOI: 10.1016/S0959-437X(00)00200-8 |
0.337 |
|
| 2001 |
Woods YL, Cohen P, Becker W, Jakes R, Goedert M, Wang X, Proud CG. The kinase DYRK phosphorylates protein-synthesis initiation factor eIF2Bepsilon at Ser539 and the microtubule-associated protein tau at Thr212: potential role for DYRK as a glycogen synthase kinase 3-priming kinase. The Biochemical Journal. 355: 609-15. PMID 11311121 DOI: 10.1042/Bj3550609 |
0.37 |
|
| 2001 |
Goedert M, Spillantini MG, Serpell LC, Berriman J, Smith MJ, Jakes R, Crowther RA. From genetics to pathology: tau and alpha-synuclein assemblies in neurodegenerative diseases. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 356: 213-27. PMID 11260802 DOI: 10.1098/Rstb.2000.0767 |
0.343 |
|
| 2001 |
Götz J, Tolnay M, Barmettler R, Ferrari A, Bürki K, Goedert M, Probst A, Nitsch RM. Human Tau Transgenic Mice Advances in Experimental Medicine and Biology. 487: 71-83. DOI: 10.1007/978-1-4615-1249-3_6 |
0.461 |
|
| 2000 |
Goedert M, Ghetti B, Spillantini MG. Tau gene mutations in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17). Their relevance for understanding the neurogenerative process. Annals of the New York Academy of Sciences. 920: 74-83. PMID 11193179 DOI: 10.1111/J.1749-6632.2000.Tb06907.X |
0.503 |
|
| 2000 |
Ghetti B, Murrell JR, Zolo P, Spillantini MG, Goedert M. Progress in hereditary tauopathies: a mutation in the Tau gene (G389R) causes a Pick disease-like syndrome. Annals of the New York Academy of Sciences. 920: 52-62. PMID 11193177 DOI: 10.1111/J.1749-6632.2000.Tb06905.X |
0.448 |
|
| 2000 |
Götz J, Barmettler R, Ferrari A, Goedert M, Probst A, Nitsch RM. In vivo analysis of wild-type and FTDP-17 tau transgenic mice. Annals of the New York Academy of Sciences. 920: 126-33. PMID 11193141 DOI: 10.1111/J.1749-6632.2000.Tb06914.X |
0.439 |
|
| 2000 |
Spillantini MG, Yoshida H, Rizzini C, Lantos PL, Khan N, Rossor MN, Goedert M, Brown J. A novel tau mutation (N296N) in familial dementia with swollen achromatic neurons and corticobasal inclusion bodies. Annals of Neurology. 48: 939-43. PMID 11117553 DOI: 10.1002/1531-8249(200012)48:6<939::Aid-Ana17>3.0.Co;2-1 |
0.417 |
|
| 2000 |
Rizzini C, Goedert M, Hodges JR, Smith MJ, Jakes R, Hills R, Xuereb JH, Crowther RA, Spillantini MG. Tau gene mutation K257T causes a tauopathy similar to Pick's disease. Journal of Neuropathology and Experimental Neurology. 59: 990-1001. PMID 11089577 DOI: 10.1093/Jnen/59.11.990 |
0.473 |
|
| 2000 |
Smith MJ, Crowther RA, Goedert M. The natural osmolyte trimethylamine N-oxide (TMAO) restores the ability of mutant tau to promote microtubule assembly. Febs Letters. 484: 265-70. PMID 11078890 DOI: 10.1016/S0014-5793(00)02169-4 |
0.438 |
|
| 2000 |
Fleming Y, Armstrong CG, Morrice N, Paterson A, Goedert M, Cohen P. Synergistic activation of stress-activated protein kinase 1/c-Jun N-terminal kinase (SAPK1/JNK) isoforms by mitogen-activated protein kinase kinase 4 (MKK4) and MKK7. The Biochemical Journal. 352: 145-54. PMID 11062067 DOI: 10.1042/Bj3520145 |
0.322 |
|
| 2000 |
Goedert M, Satumtira S, Jakes R, Smith MJ, Kamibayashi C, White CL, Sontag E. Reduced binding of protein phosphatase 2A to tau protein with frontotemporal dementia and parkinsonism linked to chromosome 17 mutations. Journal of Neurochemistry. 75: 2155-62. PMID 11032905 DOI: 10.1046/J.1471-4159.2000.0752155.X |
0.445 |
|
| 2000 |
Spillantini MG, Van Swieten JC, Goedert M. Tau gene mutations in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17). Neurogenetics. 2: 193-205. PMID 10983715 DOI: 10.1007/Pl00022972 |
0.489 |
|
| 2000 |
Crowther RA, Goedert M. Abnormal tau-containing filaments in neurodegenerative diseases. Journal of Structural Biology. 130: 271-9. PMID 10940231 DOI: 10.1006/Jsbi.2000.4270 |
0.487 |
|
| 2000 |
Goedert M, Spillantini MG. Tau mutations in frontotemporal dementia FTDP-17 and their relevance for Alzheimer's disease. Biochimica Et Biophysica Acta. 1502: 110-21. PMID 10899436 DOI: 10.1016/S0925-4439(00)00037-5 |
0.5 |
|
| 2000 |
Probst A, Götz J, Wiederhold KH, Tolnay M, Mistl C, Jaton AL, Hong M, Ishihara T, Lee VM, Trojanowski JQ, Jakes R, Crowther RA, Spillantini MG, Bürki K, Goedert M. Axonopathy and amyotrophy in mice transgenic for human four-repeat tau protein. Acta Neuropathologica. 99: 469-81. PMID 10805089 DOI: 10.1007/S004010051148 |
0.438 |
|
| 2000 |
Duff K, Knight H, Refolo LM, Sanders S, Yu X, Picciano M, Malester B, Hutton M, Adamson J, Goedert M, Burki K, Davies P. Characterization of pathology in transgenic mice over-expressing human genomic and cDNA tau transgenes. Neurobiology of Disease. 7: 87-98. PMID 10783293 DOI: 10.1006/Nbdi.1999.0279 |
0.392 |
|
| 2000 |
Serpell LC, Berriman J, Jakes R, Goedert M, Crowther RA. Fiber diffraction of synthetic alpha-synuclein filaments shows amyloid-like cross-beta conformation. Proceedings of the National Academy of Sciences of the United States of America. 97: 4897-902. PMID 10781096 DOI: 10.1073/Pnas.97.9.4897 |
0.333 |
|
| 2000 |
Spillantini MG, Goedert M. Tau mutations in familial frontotemporal dementia. Brain : a Journal of Neurology. 123: 857-9. PMID 10775532 DOI: 10.1093/Brain/123.5.857 |
0.452 |
|
| 2000 |
Yasuda M, Takamatsu J, D'Souza I, Crowther RA, Kawamata T, Hasegawa M, Hasegawa H, Spillantini MG, Tanimukai S, Poorkaj P, Varani L, Varani G, Iwatsubo T, Goedert M, Schellenberg DG, et al. A novel mutation at position +12 in the intron following exon 10 of the tau gene in familial frontotemporal dementia (FTD-Kumamoto) Annals of Neurology. 47: 422-9. PMID 10762152 DOI: 10.1002/1531-8249(200004)47:4<422::Aid-Ana4>3.0.Co;2-G |
0.426 |
|
| 1999 |
Goedert M, Klug A. Tau protein and the paired helical filament of Alzheimer's disease. Brain Research Bulletin. 50: 469-70. PMID 10643488 DOI: 10.1016/S0361-9230(99)00138-0 |
0.456 |
|
| 1999 |
Murrell JR, Spillantini MG, Zolo P, Guazzelli M, Smith MJ, Hasegawa M, Redi F, Crowther RA, Pietrini P, Ghetti B, Goedert M. Tau gene mutation G389R causes a tauopathy with abundant pick body-like inclusions and axonal deposits. Journal of Neuropathology and Experimental Neurology. 58: 1207-26. PMID 10604746 DOI: 10.1097/00005072-199912000-00002 |
0.447 |
|
| 1999 |
Börsch-Haubold AG, Ghomashchi F, Pasquet S, Goedert M, Cohen P, Gelb MH, Watson SP. Phosphorylation of cytosolic phospholipase A2 in platelets is mediated by multiple stress-activated protein kinase pathways. European Journal of Biochemistry / Febs. 265: 195-203. PMID 10491174 DOI: 10.1046/J.1432-1327.1999.00722.X |
0.323 |
|
| 1999 |
Goedert M. Filamentous nerve cell inclusions in neurodegenerative diseases: tauopathies and alpha-synucleinopathies. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 354: 1101-18. PMID 10434313 DOI: 10.1098/Rstb.1999.0466 |
0.448 |
|
| 1999 |
Varani L, Hasegawa M, Spillantini MG, Smith MJ, Murrell JR, Ghetti B, Klug A, Goedert M, Varani G. Structure of tau exon 10 splicing regulatory element RNA and destabilization by mutations of frontotemporal dementia and parkinsonism linked to chromosome 17. Proceedings of the National Academy of Sciences of the United States of America. 96: 8229-34. PMID 10393977 DOI: 10.1073/Pnas.96.14.8229 |
0.334 |
|
| 1999 |
Goedert M. Alzheimer's disease. Pinning down phosphorylated tau. Nature. 399: 739-40. PMID 10391237 DOI: 10.1038/21550 |
0.479 |
|
| 1999 |
Spillantini MG, Tolnay M, Love S, Goedert M. Microtubule-associated protein tau, heparan sulphate and alpha-synuclein in several neurodegenerative diseases with dementia. Acta Neuropathologica. 97: 585-94. PMID 10378377 DOI: 10.1007/S004010051034 |
0.377 |
|
| 1999 |
Bugiani O, Murrell JR, Giaccone G, Hasegawa M, Ghigo G, Tabaton M, Morbin M, Primavera A, Carella F, Solaro C, Grisoli M, Savoiardo M, Spillantini MG, Tagliavini F, Goedert M, et al. Frontotemporal dementia and corticobasal degeneration in a family with a P301S mutation in tau. Journal of Neuropathology and Experimental Neurology. 58: 667-77. PMID 10374757 DOI: 10.1097/00005072-199906000-00011 |
0.42 |
|
| 1999 |
Goedert M, Jakes R, Crowther RA. Effects of frontotemporal dementia FTDP-17 mutations on heparin-induced assembly of tau filaments. Febs Letters. 450: 306-11. PMID 10359094 DOI: 10.1016/S0014-5793(99)00508-6 |
0.403 |
|
| 1999 |
Mirra SS, Murrell JR, Gearing M, Spillantini MG, Goedert M, Crowther RA, Levey AI, Jones R, Green J, Shoffner JM, Wainer BH, Schmidt ML, Trojanowski JQ, Ghetti B. Tau pathology in a family with dementia and a P301L mutation in tau. Journal of Neuropathology and Experimental Neurology. 58: 335-45. PMID 10218629 DOI: 10.1097/00005072-199904000-00004 |
0.467 |
|
| 1999 |
Goedert M, Spillantini MG, Crowther RA, Chen SG, Parchi P, Tabaton M, Lanska DJ, Markesbery WR, Wilhelmsen KC, Dickson DW, Petersen RB, Gambetti P. Tau gene mutation in familial progressive subcortical gliosis. Nature Medicine. 5: 454-7. PMID 10202939 DOI: 10.1038/7454 |
0.423 |
|
| 1999 |
Hasegawa M, Smith MJ, Iijima M, Tabira T, Goedert M. FTDP-17 mutations N279K and S305N in tau produce increased splicing of exon 10. Febs Letters. 443: 93-6. PMID 9989582 DOI: 10.1016/S0014-5793(98)01696-2 |
0.354 |
|
| 1999 |
Rizzu P, Van Swieten JC, Joosse M, Hasegawa M, Stevens M, Tibben A, Niermeijer MF, Hillebrand M, Ravid R, Oostra BA, Goedert M, van Duijn CM, Heutink P. High prevalence of mutations in the microtubule-associated protein tau in a population study of frontotemporal dementia in the Netherlands. American Journal of Human Genetics. 64: 414-21. PMID 9973279 DOI: 10.1086/302256 |
0.402 |
|
| 1999 |
Goedert M, Hasegawa M. The tauopathies: toward an experimental animal model. The American Journal of Pathology. 154: 1-6. PMID 9916910 DOI: 10.1016/S0002-9440(10)65242-X |
0.499 |
|
| 1998 |
Trojanowski JQ, Goedert M, Iwatsubo T, Lee VM. Fatal attractions: abnormal protein aggregation and neuron death in Parkinson's disease and Lewy body dementia. Cell Death and Differentiation. 5: 832-7. PMID 10203692 DOI: 10.1038/Sj.Cdd.4400432 |
0.399 |
|
| 1998 |
Lawler S, Fleming Y, Goedert M, Cohen P. Synergistic activation of SAPK1/JNK1 by two MAP kinase kinases in vitro. Current Biology : Cb. 8: 1387-90. PMID 9889102 DOI: 10.1016/S0960-9822(98)00019-0 |
0.306 |
|
| 1998 |
Goedert M, Crowther RA, Spillantini MG. Tau mutations cause frontotemporal dementias. Neuron. 21: 955-8. PMID 9856453 DOI: 10.1016/S0896-6273(00)80615-7 |
0.384 |
|
| 1998 |
Hasegawa M, Smith MJ, Goedert M. Tau proteins with FTDP-17 mutations have a reduced ability to promote microtubule assembly. Febs Letters. 437: 207-10. PMID 9824291 DOI: 10.1016/S0014-5793(98)01217-4 |
0.395 |
|
| 1998 |
Goedert M, Spillantini MG, Davies SW. Filamentous nerve cell inclusions in neurodegenerative diseases. Current Opinion in Neurobiology. 8: 619-32. PMID 9811617 DOI: 10.1016/S0959-4388(98)80090-1 |
0.436 |
|
| 1998 |
Spillantini MG, Goedert M. Tau protein pathology in neurodegenerative diseases. Trends in Neurosciences. 21: 428-33. PMID 9786340 DOI: 10.1016/S0166-2236(98)01337-X |
0.492 |
|
| 1998 |
Jensen PH, Nielsen MS, Jakes R, Dotti CG, Goedert M. Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation. The Journal of Biological Chemistry. 273: 26292-4. PMID 9756856 DOI: 10.1074/Jbc.273.41.26292 |
0.382 |
|
| 1998 |
Spillantini MG, Crowther RA, Jakes R, Cairns NJ, Lantos PL, Goedert M. Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies. Neuroscience Letters. 251: 205-8. PMID 9726379 DOI: 10.1016/S0304-3940(98)00504-7 |
0.37 |
|
| 1998 |
Cohen P, Goedert M. Engineering protein kinases with distinct nucleotide specificities and inhibitor sensitivities by mutation of a single amino acid. Chemistry & Biology. 5: R161-4. PMID 9662509 DOI: 10.1016/S1074-5521(98)90068-0 |
0.301 |
|
| 1998 |
Eyers PA, Craxton M, Morrice N, Cohen P, Goedert M. Conversion of SB 203580-insensitive MAP kinase family members to drug-sensitive forms by a single amino-acid substitution. Chemistry & Biology. 5: 321-8. PMID 9653550 DOI: 10.1016/S1074-5521(98)90170-3 |
0.319 |
|
| 1998 |
Spillantini MG, Murrell JR, Goedert M, Farlow MR, Klug A, Ghetti B. Mutation in the tau gene in familial multiple system tauopathy with presenile dementia. Proceedings of the National Academy of Sciences of the United States of America. 95: 7737-41. PMID 9636220 DOI: 10.1073/Pnas.95.13.7737 |
0.467 |
|
| 1998 |
Spillantini MG, Crowther RA, Jakes R, Hasegawa M, Goedert M. alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies. Proceedings of the National Academy of Sciences of the United States of America. 95: 6469-73. PMID 9600990 DOI: 10.1073/Pnas.95.11.6469 |
0.372 |
|
| 1998 |
Qi Z, Zhu X, Goedert M, Fujita DJ, Wang JH. Effect of heparin on phosphorylation site specificity of neuronal Cdc2-like kinase. Febs Letters. 423: 227-30. PMID 9512362 DOI: 10.1016/S0014-5793(98)00096-9 |
0.333 |
|
| 1997 |
Hasegawa M, Crowther RA, Jakes R, Goedert M. Alzheimer-like changes in microtubule-associated protein Tau induced by sulfated glycosaminoglycans. Inhibition of microtubule binding, stimulation of phosphorylation, and filament assembly depend on the degree of sulfation. The Journal of Biological Chemistry. 272: 33118-24. PMID 9407097 DOI: 10.1074/Jbc.272.52.33118 |
0.494 |
|
| 1997 |
Murrell JR, Koller D, Foroud T, Goedert M, Spillantini MG, Edenberg HJ, Farlow MR, Ghetti B. Familial multiple-system tauopathy with presenile dementia is localized to chromosome 17. American Journal of Human Genetics. 61: 1131-8. PMID 9345089 DOI: 10.1086/301594 |
0.322 |
|
| 1997 |
Spillantini MG, Schmidt ML, Lee VM, Trojanowski JQ, Jakes R, Goedert M. Alpha-synuclein in Lewy bodies. Nature. 388: 839-40. PMID 9278044 DOI: 10.1038/42166 |
0.39 |
|
| 1997 |
Sergeant N, David JP, Goedert M, Jakes R, Vermersch P, Buée L, Lefranc D, Wattez A, Delacourte A. Two-dimensional characterization of paired helical filament-tau from Alzheimer's disease: demonstration of an additional 74-kDa component and age-related biochemical modifications. Journal of Neurochemistry. 69: 834-44. PMID 9231745 DOI: 10.1046/J.1471-4159.1997.69020834.X |
0.474 |
|
| 1997 |
Goedert M, Cuenda A, Craxton M, Jakes R, Cohen P. Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases. The Embo Journal. 16: 3563-71. PMID 9218798 DOI: 10.1093/Emboj/16.12.3563 |
0.3 |
|
| 1997 |
Goedert M, Hasegawa M, Jakes R, Lawler S, Cuenda A, Cohen P. Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases. Febs Letters. 409: 57-62. PMID 9199504 DOI: 10.1016/S0014-5793(97)00483-3 |
0.455 |
|
| 1997 |
Goedert M, Hasegawa J, Craxton M, Leversha MA, Clegg S. Assignment of the human stress-activated protein kinase-3 gene (SAPK3) to chromosome 22q13.3 by fluorescence in situ hybridization. Genomics. 41: 501-2. PMID 9169156 DOI: 10.1006/Geno.1997.4633 |
0.305 |
|
| 1997 |
Tolnay M, Spillantini MG, Goedert M, Ulrich J, Langui D, Probst A. Argyrophilic grain disease: widespread hyperphosphorylation of tau protein in limbic neurons. Acta Neuropathologica. 93: 477-84. PMID 9144586 DOI: 10.1007/S004010050642 |
0.472 |
|
| 1997 |
Spillantini MG, Goedert M, Crowther RA, Murrell JR, Farlow MR, Ghetti B. Familial multiple system tauopathy with presenile dementia: a disease with abundant neuronal and glial tau filaments. Proceedings of the National Academy of Sciences of the United States of America. 94: 4113-8. PMID 9108114 DOI: 10.1073/Pnas.94.8.4113 |
0.491 |
|
| 1997 |
Cuenda A, Cohen P, Buée-Scherrer V, Goedert M. Activation of stress-activated protein kinase-3 (SAPK3) by cytokines and cellular stresses is mediated via SAPKK3 (MKK6); comparison of the specificities of SAPK3 and SAPK2 (RK/p38). The Embo Journal. 16: 295-305. PMID 9029150 DOI: 10.1093/Emboj/16.2.295 |
0.303 |
|
| 1997 |
Goedert M. The Neurofibrillary Pathology of Alzheimer's Disease: The Neuroscientist. 3: 131-141. DOI: 10.1177/107385849700300212 |
0.48 |
|
| 1996 |
Goedert M, Spillantini MG, Hasegawa M, Jakes R, Crowther RA, Klug A. Molecular dissection of the neurofibrillary lesions of Alzheimer's disease. Cold Spring Harbor Symposia On Quantitative Biology. 61: 565-73. PMID 9246483 DOI: 10.1101/Sqb.1996.061.01.057 |
0.331 |
|
| 1996 |
Probst A, Tolnay M, Langui D, Goedert M, Spillantini MG. Pick's disease: hyperphosphorylated tau protein segregates to the somatoaxonal compartment. Acta Neuropathologica. 92: 588-96. PMID 8960316 DOI: 10.1007/S004010050565 |
0.475 |
|
| 1996 |
Goedert M, Jakes R, Spillantini MG, Hasegawa M, Smith MJ, Crowther RA. Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans. Nature. 383: 550-3. PMID 8849730 DOI: 10.1038/383550A0 |
0.5 |
|
| 1996 |
Spillantini MG, Crowther RA, Goedert M. Comparison of the neurofibrillary pathology in Alzheimer's disease and familial presenile dementia with tangles. Acta Neuropathologica. 92: 42-8. PMID 8811124 DOI: 10.1007/S004010050487 |
0.456 |
|
| 1996 |
Buée-Scherrer V, Condamines O, Mourton-Gilles C, Jakes R, Goedert M, Pau B, Delacourte A. AD2, a phosphorylation-dependent monoclonal antibody directed against tau proteins found in Alzheimer's disease. Brain Research. Molecular Brain Research. 39: 79-88. PMID 8804716 DOI: 10.1016/0169-328X(96)00003-4 |
0.477 |
|
| 1996 |
Hasegawa M, Jakes R, Crowther RA, Lee VM, Ihara Y, Goedert M. Characterization of mAb AP422, a novel phosphorylation-dependent monoclonal antibody against tau protein. Febs Letters. 384: 25-30. PMID 8797796 DOI: 10.1016/0014-5793(96)00271-2 |
0.455 |
|
| 1996 |
Andrä K, Abramowski D, Duke M, Probst A, Wiederhold KH, Bürki K, Goedert M, Sommer B, Staufenbiel M. Expression of APP in transgenic mice: a comparison of neuron-specific promoters. Neurobiology of Aging. 17: 183-90. PMID 8744399 DOI: 10.1016/0197-4580(95)02066-7 |
0.363 |
|
| 1996 |
Litersky JM, Johnson GV, Jakes R, Goedert M, Lee M, Seubert P. Tau protein is phosphorylated by cyclic AMP-dependent protein kinase and calcium/calmodulin-dependent protein kinase II within its microtubule-binding domains at Ser-262 and Ser-356. The Biochemical Journal. 316: 655-60. PMID 8687413 DOI: 10.1042/Bj3160655 |
0.406 |
|
| 1996 |
Roses AD, Einstein G, Gilbert J, Goedert M, Han SH, Huang D, Hulette C, Masliah E, Pericak-Vance MA, Saunders AM, Schmechel DE, Strittmatter WJ, Weisgraber KH, Xi PT. Morphological, biochemical, and genetic support for an apolipoprotein E effect on microtubular metabolism. Annals of the New York Academy of Sciences. 777: 146-57. PMID 8624078 DOI: 10.1111/J.1749-6632.1996.Tb34413.X |
0.415 |
|
| 1996 |
Goedert M. Tau protein and the neurofibrillary pathology of Alzheimer's disease. Annals of the New York Academy of Sciences. 777: 121-31. PMID 8624074 DOI: 10.1111/J.1749-6632.1996.Tb34410.X |
0.409 |
|
| 1996 |
Ghetti B, Piccardo P, Spillantini MG, Ichimiya Y, Porro M, Perini F, Kitamoto T, Tateishi J, Seiler C, Frangione B, Bugiani O, Giaccone G, Prelli F, Goedert M, Dlouhy SR, et al. Vascular variant of prion protein cerebral amyloidosis with tau-positive neurofibrillary tangles: the phenotype of the stop codon 145 mutation in PRNP. Proceedings of the National Academy of Sciences of the United States of America. 93: 744-8. PMID 8570627 DOI: 10.1073/Pnas.93.2.744 |
0.427 |
|
| 1996 |
Ghetti B, Farlow MR, Crowther RA, Goedert M, Spillantini MG. HEREDITARY MULTIPLE SYSTEM DEGENERATION WITH PRESENILE DEMENTIA Journal of Neuropathology and Experimental Neurology. 55: 608. DOI: 10.1097/00005072-199605000-00026 |
0.324 |
|
| 1996 |
Gougat C, Pérachon S, Goedert M, Condamines O, Delacourte A, Pau B, Granier C, Mourton-Gilles C. 404 Molecular characterization of the epitopes of two anti PHF-Tau monoclonal antibodies used in an immunoassay for the mapping of neurofibrillary degeneration in Alzheimer's disease Neurobiology of Aging. 17: S101. DOI: 10.1016/S0197-4580(96)80406-4 |
0.378 |
|
| 1995 |
Sperber BR, Leight S, Goedert M, Lee VM. Glycogen synthase kinase-3 beta phosphorylates tau protein at multiple sites in intact cells. Neuroscience Letters. 197: 149-53. PMID 8552282 |
0.329 |
|
| 1995 |
Goedert M, Jakes R, Spillantini MG, Crowther RA, Cohen P, Vanmechelen E, Probst A, Götz J, Bürki K. Tau protein in Alzheimer's disease. Biochemical Society Transactions. 23: 80-5. PMID 7758799 DOI: 10.1042/Bst0230080 |
0.444 |
|
| 1995 |
Götz J, Probst A, Spillantini MG, Schäfer T, Jakes R, Bürki K, Goedert M. Somatodendritic localization and hyperphosphorylation of tau protein in transgenic mice expressing the longest human brain tau isoform. The Embo Journal. 14: 1304-13. PMID 7729409 DOI: 10.1002/J.1460-2075.1995.Tb07116.X |
0.482 |
|
| 1995 |
Seubert P, Mawal-Dewan M, Barbour R, Jakes R, Goedert M, Johnson GV, Litersky JM, Schenk D, Lieberburg I, Trojanowski JQ. Detection of phosphorylated Ser262 in fetal tau, adult tau, and paired helical filament tau. The Journal of Biological Chemistry. 270: 18917-22. PMID 7642549 DOI: 10.1074/Jbc.270.32.18917 |
0.473 |
|
| 1995 |
Goedert M, Jakes R, Vanmechelen E. Monoclonal antibody AT8 recognises tau protein phosphorylated at both serine 202 and threonine 205. Neuroscience Letters. 189: 167-9. PMID 7624036 DOI: 10.1016/0304-3940(95)11484-E |
0.471 |
|
| 1995 |
Huang DY, Weisgraber KH, Goedert M, Saunders AM, Roses AD, Strittmatter WJ. ApoE3 binding to tau tandem repeat I is abolished by tau serine262 phosphorylation. Neuroscience Letters. 192: 209-12. PMID 7566652 DOI: 10.1016/0304-3940(95)11649-H |
0.451 |
|
| 1995 |
Goedert M, Spillantini MG, Jakes R, Crowther RA, Vanmechelen E, Probst A, Götz J, Bürki K, Cohen P. Molecular dissection of the paired helical filament. Neurobiology of Aging. 16: 325-34. PMID 7566342 DOI: 10.1016/0197-4580(95)00017-9 |
0.476 |
|
| 1995 |
Spillantini MG, Divane A, Goedert M. Assignment of human alpha-synuclein (SNCA) and beta-synuclein (SNCB) genes to chromosomes 4q21 and 5q35. Genomics. 27: 379-81. PMID 7558013 DOI: 10.1006/Geno.1995.1063 |
0.366 |
|
| 1994 |
Strittmatter WJ, Weisgraber KH, Goedert M, Saunders AM, Huang D, Corder EH, Dong LM, Jakes R, Alberts MJ, Gilbert JR. Hypothesis: microtubule instability and paired helical filament formation in the Alzheimer disease brain are related to apolipoprotein E genotype. Experimental Neurology. 125: 163-71; discussion 1. PMID 8313935 DOI: 10.1006/Exnr.1994.1019 |
0.436 |
|
| 1994 |
Crowther RA, Olesen OF, Smith MJ, Jakes R, Goedert M. Assembly of Alzheimer-like filaments from full-length tau protein. Febs Letters. 337: 135-8. PMID 8287967 DOI: 10.1016/0014-5793(94)80260-2 |
0.485 |
|
| 1994 |
Jakes R, Spillantini MG, Goedert M. Identification of two distinct synucleins from human brain. Febs Letters. 345: 27-32. PMID 8194594 DOI: 10.1016/0014-5793(94)00395-5 |
0.379 |
|
| 1994 |
Strittmatter WJ, Saunders AM, Goedert M, Weisgraber KH, Dong LM, Jakes R, Huang DY, Pericak-Vance M, Schmechel D, Roses AD. Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 91: 11183-6. PMID 7972031 DOI: 10.1073/Pnas.91.23.11183 |
0.462 |
|
| 1994 |
Goedert M, Strittmatter WJ, Roses AD. Alzheimer's disease. Risky apolipoprotein in brain. Nature. 372: 45-6. PMID 7969418 DOI: 10.1038/372045A0 |
0.366 |
|
| 1994 |
Huang DY, Goedert M, Jakes R, Weisgraber KH, Garner CC, Saunders AM, Pericak-Vance MA, Schmechel DE, Roses AD, Strittmatter WJ. Isoform-specific interactions of apolipoprotein E with the microtubule-associated protein MAP2c: implications for Alzheimer's disease. Neuroscience Letters. 182: 55-8. PMID 7891887 DOI: 10.1016/0304-3940(94)90204-6 |
0.448 |
|
| 1994 |
Fawcett JW, Mathews G, Housden E, Goedert M, Matus A. Regenerating sciatic nerve axons contain the adult rather than the embryonic pattern of microtubule associated proteins. Neuroscience. 61: 789-804. PMID 7838378 DOI: 10.1016/0306-4522(94)90402-2 |
0.325 |
|
| 1994 |
Otvos L, Feiner L, Lang E, Szendrei GI, Goedert M, Lee VM. Monoclonal antibody PHF-1 recognizes tau protein phosphorylated at serine residues 396 and 404. Journal of Neuroscience Research. 39: 669-73. PMID 7534834 DOI: 10.1002/Jnr.490390607 |
0.385 |
|
| 1994 |
Goedert M, Jakes R, Crowther RA, Cohen P, Vanmechelen E, Vandermeeren M, Cras P. Epitope mapping of monoclonal antibodies to the paired helical filaments of Alzheimer's disease: identification of phosphorylation sites in tau protein. The Biochemical Journal. 301: 871-7. PMID 7519852 DOI: 10.1042/Bj3010871 |
0.444 |
|
| 1993 |
Goedert M, Jakes R, Crowther RA, Six J, Lübke U, Vandermeeren M, Cras P, Trojanowski JQ, Lee VM. The abnormal phosphorylation of tau protein at Ser-202 in Alzheimer disease recapitulates phosphorylation during development. Proceedings of the National Academy of Sciences of the United States of America. 90: 5066-70. PMID 8506352 DOI: 10.1073/Pnas.90.11.5066 |
0.456 |
|
| 1993 |
Lee JH, Goedert M, Hill WD, Lee VM, Trojanowski JQ. Tau proteins are abnormally expressed in olfactory epithelium of Alzheimer patients and developmentally regulated in human fetal spinal cord. Experimental Neurology. 121: 93-105. PMID 8495714 DOI: 10.1006/Exnr.1993.1074 |
0.433 |
|
| 1993 |
Bramblett GT, Goedert M, Jakes R, Merrick SE, Trojanowski JQ, Lee VM. Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding. Neuron. 10: 1089-99. PMID 8318230 DOI: 10.1016/0896-6273(93)90057-X |
0.436 |
|
| 1993 |
Lo MM, Fieles AW, Norris TE, Dargis PG, Caputo CB, Scott CW, Lee VM, Goedert M. Human tau isoforms confer distinct morphological and functional properties to stably transfected fibroblasts. Brain Research. Molecular Brain Research. 20: 209-20. PMID 8302159 DOI: 10.1016/0169-328X(93)90043-O |
0.394 |
|
| 1993 |
Robertson J, Loviny TL, Goedert M, Jakes R, Murray KJ, Anderton BH, Hanger DP. Phosphorylation of tau by cyclic-AMP-dependent protein kinase. Dementia (Basel, Switzerland). 4: 256-63. PMID 8261023 DOI: 10.1159/000107331 |
0.439 |
|
| 1993 |
Goedert M. Tau protein and the neurofibrillary pathology of Alzheimer's disease. Trends in Neurosciences. 16: 460-5. PMID 7507619 DOI: 10.1016/0166-2236(93)90078-Z |
0.511 |
|
| 1993 |
Bramblelt GT, Goedert M, Jakes R, Merrick SE, Trojanowski JO, Lee V. The Abnormal Phosphorylation Of Tau At Ser396 In AlzheimerʼS Disease Recapitulates Phosphorylation During Development And Contributes To Reduced Microtubule Binding Journal of Neuropathology and Experimental Neurology. 52: 305. DOI: 10.1097/00005072-199305000-00179 |
0.415 |
|
| 1992 |
Gustke N, Steiner B, Mandelkow EM, Biernat J, Meyer HE, Goedert M, Mandelkow E. The Alzheimer-like phosphorylation of tau protein reduces microtubule binding and involves Ser-Pro and Thr-Pro motifs. Febs Letters. 307: 199-205. PMID 1644173 DOI: 10.1016/0014-5793(92)80767-B |
0.438 |
|
| 1992 |
Biernat J, Mandelkow EM, Schröter C, Lichtenberg-Kraag B, Steiner B, Berling B, Meyer H, Mercken M, Vandermeeren A, Goedert M. The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region. The Embo Journal. 11: 1593-7. PMID 1563356 DOI: 10.1002/J.1460-2075.1992.Tb05204.X |
0.453 |
|
| 1992 |
Goedert M, Spillantini MG, Crowther RA. Cloning of a big tau microtubule-associated protein characteristic of the peripheral nervous system. Proceedings of the National Academy of Sciences of the United States of America. 89: 1983-7. PMID 1542696 DOI: 10.1073/Pnas.89.5.1983 |
0.435 |
|
| 1992 |
Goedert M, Spillantini MG, Cairns NJ, Crowther RA. Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms. Neuron. 8: 159-68. PMID 1530909 DOI: 10.1016/0896-6273(92)90117-V |
0.449 |
|
| 1992 |
Crowther RA, Olesen OF, Jakes R, Goedert M. The microtubule binding repeats of tau protein assemble into filaments like those found in Alzheimer's disease. Febs Letters. 309: 199-202. PMID 1505683 DOI: 10.1016/0014-5793(92)81094-3 |
0.479 |
|
| 1992 |
Goedert M, Cohen ES, Jakes R, Cohen P. p42 MAP kinase phosphorylation sites in microtubule-associated protein tau are dephosphorylated by protein phosphatase 2A1. Implications for Alzheimer's disease [corrected]. Febs Letters. 312: 95-9. PMID 1330687 DOI: 10.1016/0014-5793(92)81418-L |
0.447 |
|
| 1992 |
Hanger D, Loviny T, Robertson J, Goedert M, Murray K, Anderton B. Cyclic AMP-dependent protein kinase induces a shift in the electrophoretic mobility of human tau Neurobiology of Aging. 13: S54. DOI: 10.1016/0197-4580(92)90339-Y |
0.367 |
|
| 1991 |
Wright AF, Goedert M, Hastie ND. Familial Alzheimer's disease. Beta amyloid resurrected. Nature. 349: 653-4. PMID 1899915 DOI: 10.1038/349653A0 |
0.329 |
|
| 1991 |
Goedert M, Spillantini MG, Jakes R. Localization of the Alz-50 epitope in recombinant human microtubule-associated protein tau. Neuroscience Letters. 126: 149-54. PMID 1717895 DOI: 10.1016/0304-3940(91)90541-Z |
0.487 |
|
| 1991 |
Goedert M, Crowther RA, Garner CC. Molecular characterization of microtubule-associated proteins tau and MAP2. Trends in Neurosciences. 14: 193-9. PMID 1713721 DOI: 10.1016/0166-2236(91)90105-4 |
0.406 |
|
| 1991 |
Goedert M, Spillantini MG, Crowther RA. Tau proteins and neurofibrillary degeneration. Brain Pathology (Zurich, Switzerland). 1: 279-86. PMID 1669718 DOI: 10.1111/J.1750-3639.1991.Tb00671.X |
0.474 |
|
| 1990 |
Goedert M, Jakes R. Expression of separate isoforms of human tau protein: correlation with the tau pattern in brain and effects on tubulin polymerization. The Embo Journal. 9: 4225-30. PMID 2124967 DOI: 10.1002/J.1460-2075.1990.Tb07870.X |
0.385 |
|
| 1990 |
Spillantini MG, Goedert M, Jakes R, Klug A. Different configurational states of beta-amyloid and their distributions relative to plaques and tangles in Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 87: 3947-51. PMID 2111023 DOI: 10.1073/Pnas.87.10.3947 |
0.343 |
|
| 1990 |
Goedert M, Spillantini MG. Molecular neuropathology of Alzheimer's disease: in situ hybridization studies. Cellular and Molecular Neurobiology. 10: 159-74. PMID 2110505 DOI: 10.1007/Bf00733642 |
0.435 |
|
| 1990 |
Spillantini MG, Goedert M, Jakes R, Klug A. Topographical relationship between beta-amyloid and tau protein epitopes in tangle-bearing cells in Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 87: 3952-6. PMID 1692627 DOI: 10.1073/Pnas.87.10.3952 |
0.417 |
|
| 1989 |
Goedert M, Crowther RA. Amyloid plaques, neurofibrillary tangles and their relevance for the study of Alzheimer's disease. Neurobiology of Aging. 10: 405-6; discussion 41. PMID 2682318 DOI: 10.1016/0197-4580(89)90076-6 |
0.455 |
|
| 1989 |
Goedert M, Fine A, Dawbarn D, Wilcock GK, Chao MV. Nerve growth factor receptor mRNA distribution in human brain: normal levels in basal forebrain in Alzheimer's disease. Brain Research. Molecular Brain Research. 5: 1-7. PMID 2538704 DOI: 10.1016/0169-328X(89)90011-9 |
0.36 |
|
| 1989 |
Crowther T, Goedert M, Wischik CM. The repeat region of microtubule-associated protein tau forms part of the core of the paired helical filament of Alzheimer's disease. Annals of Medicine. 21: 127-32. PMID 2504257 DOI: 10.3109/07853898909149199 |
0.424 |
|
| 1989 |
Goedert M, Spillantini MG, Potier MC, Ulrich J, Crowther RA. Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: differential expression of tau protein mRNAs in human brain. The Embo Journal. 8: 393-9. PMID 2498079 DOI: 10.1002/J.1460-2075.1989.Tb03390.X |
0.411 |
|
| 1989 |
Goedert M, Spillantini MG, Jakes R, Rutherford D, Crowther RA. Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease. Neuron. 3: 519-26. PMID 2484340 DOI: 10.1016/0896-6273(89)90210-9 |
0.435 |
|
| 1988 |
Goedert M, Wischik CM, Crowther RA, Walker JE, Klug A. Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau. Proceedings of the National Academy of Sciences of the United States of America. 85: 4051-5. PMID 3131773 DOI: 10.1073/Pnas.85.11.4051 |
0.442 |
|
| 1987 |
Goedert M. Neuronal localization of amyloid beta protein precursor mRNA in normal human brain and in Alzheimer's disease. The Embo Journal. 6: 3627-32. PMID 3322812 DOI: 10.1002/J.1460-2075.1987.Tb02694.X |
0.392 |
|
| 1986 |
Goedert M, Fine A, Hunt SP, Ullrich A. Nerve growth factor mRNA in peripheral and central rat tissues and in the human central nervous system: lesion effects in the rat brain and levels in Alzheimer's disease. Brain Research. 387: 85-92. PMID 3742235 DOI: 10.1016/0169-328X(86)90023-9 |
0.33 |
|
| 1985 |
Goedert M, Iversen SD, Emson PC. The effects of chronic neuroleptic treatment on neurotensin-like immunoreactivity in the rat central nervous system. Brain Research. 335: 334-6. PMID 4005561 DOI: 10.1016/0006-8993(85)90488-3 |
0.481 |
|
| 1985 |
Goedert M, Lightman SL, Mantyh PW, Hunt SP, Emson PC. Neurotensin-like immunoreactivity and neurotensin receptors in the rat hypothalamus and in the neurointermediate lobe of the pituitary gland. Brain Research. 358: 59-69. PMID 3000519 DOI: 10.1016/0006-8993(85)90948-5 |
0.497 |
|
| 1985 |
Reeve JG, Goedert M, Emson PC, Bleehen NM. Neurotensin in human small cell lung carcinoma. Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progrã¨S Dans Les Recherches Sur Le Cancer. 99: 175-6. PMID 2999916 DOI: 10.1007/978-3-642-82533-0_18 |
0.424 |
|
| 1985 |
Goedert M, Hunt SP, Mantyh PW, Emson PC. The ontogenetic development of neurotensin-like immunoreactivity and neurotensin receptors in the cat striatum. Brain Research. 352: 127-31. PMID 2988709 DOI: 10.1016/0165-3806(85)90095-1 |
0.479 |
|
| 1985 |
Emson PC, Horsfield PM, Goedert M, Rossor MN, Hawkes CH. Neurotensin in human brain: regional distribution and effects of neurological illness. Brain Research. 347: 239-44. PMID 2933123 DOI: 10.1016/0006-8993(85)90182-9 |
0.541 |
|
| 1985 |
Fitzgerald M, Wall PD, Goedert M, Emson PC. Nerve growth factor counteracts the neurophysiological and neurochemical effects of chronic sciatic nerve section. Brain Research. 332: 131-41. PMID 2581648 DOI: 10.1016/0006-8993(85)90396-8 |
0.45 |
|
| 1984 |
Goedert M, Pittaway K, Williams BJ, Emson PC. Specific binding of tritiated neurotensin to rat brain membranes: characterization and regional distribution. Brain Research. 304: 71-81. PMID 6744039 DOI: 10.1016/0006-8993(84)90862-X |
0.477 |
|
| 1984 |
Goedert M, Lightman SL, Emson PC. Neurotensin in the rat anterior pituitary gland: effects of endocrinological manipulations. Brain Research. 299: 160-3. PMID 6722564 DOI: 10.1016/0006-8993(84)90800-X |
0.468 |
|
| 1984 |
Goedert M, Sturmey N, Williams BJ, Emson PC. The comparative distribution of xenopsin- and neurotensin-like immunoreactivity in Xenopus laevis and rat tissues. Brain Research. 308: 273-80. PMID 6434152 DOI: 10.1016/0006-8993(84)91066-7 |
0.477 |
|
| 1984 |
Goedert M, Mantyh PW, Hunt SP, Emson PC. Localization of specific neurotensin binding sites in the rat adrenal gland. Brain Research. 299: 389-92. PMID 6329423 DOI: 10.1016/0006-8993(84)90726-1 |
0.464 |
|
| 1984 |
Goedert M, Pittaway K, Emson PC. Neurotensin receptors in the rat striatum: lesion studies. Brain Research. 299: 164-8. PMID 6326960 DOI: 10.1016/0006-8993(84)90801-1 |
0.481 |
|
| 1984 |
Marley PD, Lightman SL, Forsling ML, Todd K, Goedert M, Rehfeld JF, Emson PC. Localization and actions of cholecystokinin in the rat pituitary neurointermediate lobe. Endocrinology. 114: 1902-11. PMID 6325136 DOI: 10.1210/Endo-114-5-1902 |
0.618 |
|
| 1984 |
Goedert M, Mantyh PW, Emson PC, Hunt SP. Inverse relationship between neurotensin receptors and neurotensin-like immunoreactivity in cat striatum. Nature. 307: 543-6. PMID 6320012 DOI: 10.1038/307543A0 |
0.497 |
|
| 1984 |
Goedert M, Pinnock RD, Downes CP, Mantyh PW, Emson PC. Neurotensin stimulates inositol phospholipid hydrolysis in rat brain slices. Brain Research. 323: 193-7. PMID 6098333 DOI: 10.1016/0006-8993(84)90288-9 |
0.474 |
|
| 1984 |
Goedert M, Reeve JG, Emson PC, Bleehen NM. Neurotensin in human small cell lung carcinoma. British Journal of Cancer. 50: 179-83. PMID 6087865 DOI: 10.1038/Bjc.1984.160 |
0.439 |
|
| 1984 |
Goedert M, Mantyh PW, Emson PC, Hunt SP. Erratum: Inverse relationship between neurotensin receptors and neurotensin-like immunoreactivity in cat striatum Nature. 308: 84-84. DOI: 10.1038/308084C0 |
0.453 |
|
| 1983 |
Goedert M, Reynolds GP, Emson PC. Neurotensin in the adrenal medulla. Neuroscience Letters. 35: 155-60. PMID 6856193 DOI: 10.1016/0304-3940(83)90543-8 |
0.447 |
|
| 1983 |
Goedert M, Emson PC. The regional distribution of neurotensin-like immunoreactivity in central and peripheral tissues of the cat. Brain Research. 272: 291-7. PMID 6616204 DOI: 10.1016/0006-8993(83)90576-0 |
0.48 |
|
| 1983 |
Goedert M, Mantyh PW, Hunt SP, Emson PC. Mosaic distribution of neurotensin-like immunoreactivity in the cat striatum. Brain Research. 274: 176-9. PMID 6351962 DOI: 10.1016/0006-8993(83)90536-X |
0.486 |
|
| 1982 |
Goedert M, Lightman SL, Nagy JI, Marley PD, Emson PC. Neurotensin in the rat anterior pituitary gland. Nature. 298: 163-5. PMID 7088171 DOI: 10.1038/298163A0 |
0.636 |
|
| 1982 |
Emson PC, Goedert M, Horsfield P, Rioux F, St Pierre S. The regional distribution and chromatographic characterisation of neurotensin-like immunoreactivity in the rat central nervous system. Journal of Neurochemistry. 38: 992-9. PMID 7062044 DOI: 10.1111/J.1471-4159.1982.Tb05340.X |
0.503 |
|
| 1982 |
Emson PC, Goedert M, Williams B, Ninkovic M, Hunt SP. Neurotensin: regional distribution, characterization, and inactivation. Annals of the New York Academy of Sciences. 400: 198-215. PMID 6762831 DOI: 10.1111/J.1749-6632.1982.Tb31570.X |
0.433 |
|
| 1982 |
Emson PC, Goedert M, Benton H, St-Pierre S, Rioux F. The regional distribution and chromatographic characterization of neurotensin-like immunoreactivity in the rat. Advances in Biochemical Psychopharmacology. 33: 477-85. PMID 6751035 |
0.401 |
|
| 1982 |
Goedert M, Nagy JI, Emson PC. The origin of substance P in the rat submandibular gland and its major duct. Brain Research. 252: 327-33. PMID 6185178 DOI: 10.1016/0006-8993(82)90400-0 |
0.469 |
|
| 1982 |
Goedert M, Lightman SL, Emson PC. NEUROTENSIN IN THE PITUITARY GLAND Annals of the New York Academy of Sciences. 400: 411-412. DOI: 10.1111/J.1749-6632.1982.Tb31597.X |
0.423 |
|
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