Gregory A. Graf, Ph.D. - Publications

Affiliations: 
2000 University of Kentucky, Lexington, KY 
Area:
Cell Biology, Molecular Biology, Biochemistry

36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Gatineau E, Arthur G, Poupeau A, Nichols K, Spear B, Shelman N, Graf GA, Temel RE, Yiannikouris FB. The Prorenin Receptor and its Soluble Form Contribute to Lipid Homeostasis. American Journal of Physiology. Endocrinology and Metabolism. PMID 33459178 DOI: 10.1152/ajpendo.00135.2020  0.398
2019 Lifsey HC, Kaur R, Thompson BH, Bennett L, Temel RE, Graf GA. Stigmasterol stimulates transintestinal cholesterol excretion independent of liver X receptor activation in the small intestine. The Journal of Nutritional Biochemistry. 76: 108263. PMID 31759199 DOI: 10.1016/J.Jnutbio.2019.108263  0.52
2019 Zein AA, Kaur R, Hussein TOK, Graf GA, Lee JY. ABCG5/G8: a structural view to pathophysiology of the hepatobiliary cholesterol secretion. Biochemical Society Transactions. PMID 31654053 DOI: 10.1042/Bst20190130  0.377
2019 Li J, Pijut SS, Wang Y, Ji A, Kaur R, Temel RE, van der Westhuyzen DR, Graf GA. Simultaneous Determination of Biliary and Intestinal Cholesterol Secretion Reveals That CETP (Cholesteryl Ester Transfer Protein) Alters Elimination Route in Mice. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA119312952. PMID 31462090 DOI: 10.1161/Atvbaha.119.312952  0.551
2018 Patel SB, Graf G, Temel R. ABCG5 and ABCG8: More than a defense against xenosterols. Journal of Lipid Research. PMID 29728459 DOI: 10.1194/Jlr.R084244  0.415
2018 Ji A, Wang X, Pijut S, Bennett L, van der Westhuyzen DR, Graf GA. Abstract 597: Disruptions in Hepatic Insulin Signaling Reveal an Enterohepatic Signaling Pathway that Regulates the ABCG5 ABCG8 Sterol Transporter and Biliary Cholesterol Secretion Arteriosclerosis, Thrombosis, and Vascular Biology. 38. DOI: 10.1161/Atvb.38.Suppl_1.597  0.397
2017 Rotroff DM, Pijut SS, Marvel SW, Jack JR, Havener TM, Pujol A, Schluter A, Graf GA, Ginsberg HN, Shah HS, Gao H, Morieri ML, Doria A, Mychaleckyi JC, McLeod HL, et al. Genetic variants in HSD17B3, SMAD3, and IPO11 impact circulating lipids in response to fenofibrate in individuals with type 2 diabetes. Clinical Pharmacology and Therapeutics. PMID 28736931 DOI: 10.1002/Cpt.798  0.382
2017 Brown JM, Temel RE, Graf GA. Para-bile-osis Establishes a Role for Nonbiliary Macrophage to Feces Reverse Cholesterol Transport. Arteriosclerosis, Thrombosis, and Vascular Biology. 37: 738-739. PMID 28446467 DOI: 10.1161/Atvbaha.117.309224  0.46
2016 Pijut SS, Corbett DE, Wang Y, Li J, Charnigo RJ, Graf GA. Effect of peripheral circadian dysfunction on metabolic disease in response to a diabetogenic diet. American Journal of Physiology. Endocrinology and Metabolism. ajpendo.00328.2015. PMID 27048996 DOI: 10.1152/Ajpendo.00328.2015  0.474
2015 Wang Y, Su K, Sabeva NS, Ji A, van der Westhuyzen DR, Foufelle F, Gao X, Graf GA. GRP78 rescues the ABCG5 ABCG8 sterol transporter in db/db mice. Metabolism: Clinical and Experimental. PMID 26365598 DOI: 10.1016/J.Metabol.2015.08.005  0.775
2015 Wang Y, Liu X, Pijut SS, Li J, Horn J, Bradford EM, Leggas M, Barrett TA, Graf GA. The combination of ezetimibe and ursodiol promotes fecal sterol excretion and reveals a G5G8-independent pathway for cholesterol elimination. Journal of Lipid Research. 56: 810-20. PMID 25635125 DOI: 10.1194/Jlr.M053454  0.513
2015 Liu X, Liu J, Lester JD, Pijut SS, Graf GA. ABCD2 identifies a subclass of peroxisomes in mouse adipose tissue. Biochemical and Biophysical Research Communications. 456: 129-34. PMID 25446110 DOI: 10.1016/J.Bbrc.2014.11.046  0.33
2014 Liu X, Liu J, Liang S, Schlüter A, Fourcade S, Aslibekyan S, Pujol A, Graf GA. ABCD2 alters peroxisome proliferator-activated receptor α signaling in vitro, but does not impair responses to fenofibrate therapy in a mouse model of diet-induced obesity. Molecular Pharmacology. 86: 505-13. PMID 25123288 DOI: 10.1124/Mol.114.092742  0.414
2014 Su K, Sabeva NS, Wang Y, Liu X, Lester JD, Liu J, Liang S, Graf GA. Acceleration of biliary cholesterol secretion restores glycemic control and alleviates hypertriglyceridemia in obese db/db mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 26-33. PMID 24202306 DOI: 10.1161/Atvbaha.113.302355  0.783
2013 Salous AK, Panchatcharam M, Sunkara M, Mueller P, Dong A, Wang Y, Graf GA, Smyth SS, Morris AJ. Mechanism of rapid elimination of lysophosphatidic acid and related lipids from the circulation of mice. Journal of Lipid Research. 54: 2775-84. PMID 23948545 DOI: 10.1194/Jlr.M039685  0.449
2013 Meyer JM, Graf GA, van der Westhuyzen DR. New developments in selective cholesteryl ester uptake. Current Opinion in Lipidology. 24: 386-92. PMID 23842142 DOI: 10.1097/Mol.0B013E3283638042  0.454
2012 Su K, Sabeva NS, Liu J, Wang Y, Bhatnagar S, van der Westhuyzen DR, Graf GA. The ABCG5 ABCG8 sterol transporter opposes the development of fatty liver disease and loss of glycemic control independently of phytosterol accumulation. The Journal of Biological Chemistry. 287: 28564-75. PMID 22715101 DOI: 10.1074/Jbc.M112.360081  0.773
2012 Liu J, Liang S, Liu X, Brown JA, Newman KE, Sunkara M, Morris AJ, Bhatnagar S, Li X, Pujol A, Graf GA. The absence of ABCD2 sensitizes mice to disruptions in lipid metabolism by dietary erucic acid. Journal of Lipid Research. 53: 1071-9. PMID 22493092 DOI: 10.1194/Jlr.M022160  0.433
2011 Sabeva NS, McPhaul CM, Li X, Cory TJ, Feola DJ, Graf GA. Phytosterols differentially influence ABC transporter expression, cholesterol efflux and inflammatory cytokine secretion in macrophage foam cells. The Journal of Nutritional Biochemistry. 22: 777-83. PMID 21111593 DOI: 10.1016/J.Jnutbio.2010.07.002  0.762
2011 Ghoshal S, Trivedi DB, Graf GA, Loftin CD. Cyclooxygenase-2 deficiency attenuates adipose tissue differentiation and inflammation in mice. The Journal of Biological Chemistry. 286: 889-98. PMID 20961858 DOI: 10.1074/Jbc.M110.139139  0.415
2010 Coy DJ, Wooton-Kee CR, Yan B, Sabeva N, Su K, Graf G, Vore M. ABCG5/ABCG8-independent biliary cholesterol excretion in lactating rats. American Journal of Physiology. Gastrointestinal and Liver Physiology. 299: G228-35. PMID 20413720 DOI: 10.1152/Ajpgi.00502.2009  0.772
2010 Liu J, Sabeva NS, Bhatnagar S, Li XA, Pujol A, Graf GA. ABCD2 is abundant in adipose tissue and opposes the accumulation of dietary erucic acid (C22:1) in fat. Journal of Lipid Research. 51: 162-8. PMID 19556607 DOI: 10.1194/Jlr.M900237-Jlr200  0.752
2009 Sabeva NS, Liu J, Graf GA. The ABCG5 ABCG8 sterol transporter and phytosterols: implications for cardiometabolic disease. Current Opinion in Endocrinology, Diabetes, and Obesity. 16: 172-7. PMID 19306529 DOI: 10.1097/Med.0B013E3283292312  0.737
2009 Burke KT, Colvin PL, Myatt L, Graf GA, Schroeder F, Woollett LA. Transport of maternal cholesterol to the fetus is affected by maternal plasma cholesterol concentrations in the golden Syrian hamster. Journal of Lipid Research. 50: 1146-55. PMID 19122238 DOI: 10.1194/Jlr.M800538-Jlr200  0.511
2008 White J, Guerin T, Swanson H, Post S, Zhu H, Gong M, Liu J, Everson WV, Li XA, Graf GA, Ballard HO, Ross SA, Smart EJ. Diabetic HDL-associated myristic acid inhibits acetylcholine-induced nitric oxide generation by preventing the association of endothelial nitric oxide synthase with calmodulin. American Journal of Physiology. Cell Physiology. 294: C295-305. PMID 17977947 DOI: 10.1152/Ajpcell.00042.2007  0.615
2007 Sabeva NS, Rouse EJ, Graf GA. Defects in the leptin axis reduce abundance of the ABCG5-ABCG8 sterol transporter in liver. The Journal of Biological Chemistry. 282: 22397-405. PMID 17561514 DOI: 10.1074/Jbc.M702236200  0.77
2006 Zhang DW, Graf GA, Gerard RD, Cohen JC, Hobbs HH. Functional asymmetry of nucleotide-binding domains in ABCG5 and ABCG8 Journal of Biological Chemistry. 281: 4507-4516. PMID 16352607 DOI: 10.1074/Jbc.M512277200  0.325
2003 Graf GA, Yu L, Li WP, Gerard R, Tuma PL, Cohen JC, Hobbs HH. ABCG5 and ABCG8 Are Obligate Heterodimers for Protein Trafficking and Biliary Cholesterol Excretion Journal of Biological Chemistry. 278: 48275-48282. PMID 14504269 DOI: 10.1074/Jbc.M310223200  0.332
2002 Stangl H, Graf GA, Yu L, Cao G, Wyne K. Effect of estrogen on scavenger receptor BI expression in the rat. The Journal of Endocrinology. 175: 663-72. PMID 12475377 DOI: 10.1677/Joe.0.1750663  0.356
2002 Graf GA, Li WP, Gerard RD, Gelissen I, White A, Cohen JC, Hobbs HH. Coexpression of ATP-binding cassette proteins ABCG5 and ABCG8 permits their transport to the apical surface Journal of Clinical Investigation. 110: 659-669. PMID 12208867 DOI: 10.1172/Jci16000  0.335
2001 Graf GA, Roswell KL, Smart EJ. 17beta-Estradiol promotes the up-regulation of SR-BII in HepG2 cells and in rat livers. Journal of Lipid Research. 42: 1444-9. PMID 11518764  0.609
2000 Berge KE, Tian H, Graf GA, Yu L, Grishin NV, Schultz J, Kwiterovich P, Shan B, Barnes R, Hobbs HH. Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters Science. 290: 1771-1775. PMID 11099417 DOI: 10.1126/Science.290.5497.1771  0.447
1999 Graf GA, Matveev SV, Smart EJ. Class B scavenger receptors, caveolae and cholesterol homeostasis. Trends in Cardiovascular Medicine. 9: 221-5. PMID 11094329 DOI: 10.1016/S1050-1738(00)00031-1  0.67
1999 Smart EJ, Graf GA, McNiven MA, Sessa WC, Engelman JA, Scherer PE, Okamoto T, Lisanti MP. Caveolins, liquid-ordered domains, and signal transduction. Molecular and Cellular Biology. 19: 7289-304. PMID 10523618 DOI: 10.1128/Mcb.19.11.7289  0.575
1999 Graf GA, Connell PM, van der Westhuyzen DR, Smart EJ. The class B, type I scavenger receptor promotes the selective uptake of high density lipoprotein cholesterol ethers into caveolae. The Journal of Biological Chemistry. 274: 12043-8. PMID 10207027 DOI: 10.1074/Jbc.274.17.12043  0.679
1998 Webb NR, Connell PM, Graf GA, Smart EJ, de Villiers WJ, de Beer FC, van der Westhuyzen DR. SR-BII, an isoform of the scavenger receptor BI containing an alternate cytoplasmic tail, mediates lipid transfer between high density lipoprotein and cells. The Journal of Biological Chemistry. 273: 15241-8. PMID 9614139 DOI: 10.1074/jbc.273.24.15241  0.648
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