Sergey Seregin, Ph.D. - Publications

2010 Michigan State University, East Lansing, MI 
Microbiology Biology

40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Toubai T, Fujiwara H, Rossi C, Riwes M, Tamaki H, Zajac C, Liu C, Mathew AV, Byun J, Oravecz-Wilson K, Matsuda I, Sun Y, Peltier D, Wu J, Chen J, ... Seregin S, et al. Host NLRP6 exacerbates graft-versus-host disease independent of gut microbial composition. Nature Microbiology. PMID 30858572 DOI: 10.1038/s41564-019-0373-1  0.8
2018 Kady NM, Liu X, Lydic TA, Syed MH, Navitskaya S, Wang Q, Hammer SS, O'Reilly S, Huang C, Seregin SS, Amalfitano A, Chiodo VA, Boye SL, Hauswirth WW, Antonetti DA, et al. ELOVL4-Mediated Production of Very Long Chain Ceramides Stabilizes Tight Junctions and Prevents Diabetes-Induced Retinal Vascular Permeability. Diabetes. PMID 29362226 DOI: 10.2337/db17-1034  1
2016 Rastall DP, Seregin SS, Aldhamen YA, Kaiser LM, Mullins C, Liou A, Ing F, Pereria-Hicks C, Godbehere-Roosa S, Palmer D, Ng P, Amalfitano A. Long-term, high level hepatic secretion of acid α-glucosidase for Pompe disease achieved in non-human primates using helper-dependent adenovirus. Gene Therapy. PMID 27367841 DOI: 10.1038/gt.2016.53  1
2016 Aldhamen YA, Rastall DP, Chen W, Seregin SS, Pereira-Hicks C, Godbehere S, Kaminski NE, Amalfitano A. CRACC-targeting Fc-fusion protein induces activation of NK cells and DCs and improves T cell immune responses to antigenic targets. Vaccine. PMID 27151882 DOI: 10.1016/j.vaccine.2016.04.068  1
2016 Alyaqoub FS, Aldhamen YA, Koestler BJ, Bruger EL, Seregin SS, Pereira-Hicks C, Godbehere S, Waters CM, Amalfitano A. In Vivo Synthesis of Cyclic-di-GMP Using a Recombinant Adenovirus Preferentially Improves Adaptive Immune Responses against Extracellular Antigens. Journal of Immunology (Baltimore, Md. : 1950). PMID 26792800 DOI: 10.4049/jimmunol.1501272  1
2015 Seregin SS, Chen GY, Laouar Y. Dissecting CD8+ NKT Cell Responses to Listeria Infection Reveals a Component of Innate Resistance. Journal of Immunology (Baltimore, Md. : 1950). PMID 26116500 DOI: 10.4049/jimmunol.1500084  1
2015 Aldhamen YA, Pepelyayeva Y, Rastall DP, Seregin SS, Zervoudi E, Koumantou D, Aylsworth CF, Quiroga D, Godbehere S, Georgiadis D, Stratikos E, Amalfitano A. Autoimmune disease-associated variants of extracellular endoplasmic reticulum aminopeptidase 1 induce altered innate immune responses by human immune cells. Journal of Innate Immunity. 7: 275-89. PMID 25591727 DOI: 10.1159/000368899  1
2014 Koestler BJ, Seregin SS, Rastall DP, Aldhamen YA, Godbehere S, Amalfitano A, Waters CM. Stimulation of innate immunity by in vivo cyclic di-GMP synthesis using adenovirus. Clinical and Vaccine Immunology : Cvi. 21: 1550-9. PMID 25230938 DOI: 10.1128/CVI.00471-14  1
2014 Rastall DP, Aldhamen YA, Seregin SS, Godbehere S, Amalfitano A. ERAP1 functions override the intrinsic selection of specific antigens as immunodominant peptides, thereby altering the potency of antigen-specific cytolytic and effector memory T-cell responses. International Immunology. 26: 685-95. PMID 25087231 DOI: 10.1093/intimm/dxu078  1
2014 Aldhamen YA, Seregin SS, Aylsworth CF, Godbehere S, Amalfitano A. Manipulation of EAT-2 expression promotes induction of multiple beneficial regulatory and effector functions of the human innate immune system as a novel immunomodulatory strategy. International Immunology. 26: 291-303. PMID 24374770 DOI: 10.1093/intimm/dxt061  1
2013 Zervoudi E, Saridakis E, Birtley JR, Seregin SS, Reeves E, Kokkala P, Aldhamen YA, Amalfitano A, Mavridis IM, James E, Georgiadis D, Stratikos E. Rationally designed inhibitor targeting antigen-trimming aminopeptidases enhances antigen presentation and cytotoxic T-cell responses. Proceedings of the National Academy of Sciences of the United States of America. 110: 19890-5. PMID 24248368 DOI: 10.1073/pnas.1309781110  1
2013 Kovalenko PL, Yuan L, Sun K, Kunovska L, Seregin S, Amalfitano A, Basson MD. Regulation of epithelial differentiation in rat intestine by intraluminal delivery of an adenoviral vector or silencing RNA coding for Schlafen 3. Plos One. 8: e79745. PMID 24244554 DOI: 10.1371/journal.pone.0079745  1
2013 Seregin SS, Rastall DP, Evnouchidou I, Aylsworth CF, Quiroga D, Kamal RP, Godbehere-Roosa S, Blum CF, York IA, Stratikos E, Amalfitano A. Endoplasmic reticulum aminopeptidase-1 alleles associated with increased risk of ankylosing spondylitis reduce HLA-B27 mediated presentation of multiple antigens. Autoimmunity. 46: 497-508. PMID 24028501 DOI: 10.3109/08916934.2013.819855  1
2013 Aldhamen YA, Seregin SS, Kousa YA, Rastall DP, Appledorn DM, Godbehere S, Schutte BC, Amalfitano A. Improved cytotoxic T-lymphocyte immune responses to a tumor antigen by vaccines co-expressing the SLAM-associated adaptor EAT-2. Cancer Gene Therapy. 20: 564-75. PMID 23949283 DOI: 10.1038/cgt.2013.53  1
2013 Aldhamen YA, Seregin SS, Rastall DP, Aylsworth CF, Pepelyayeva Y, Busuito CJ, Godbehere-Roosa S, Kim S, Amalfitano A. Endoplasmic reticulum aminopeptidase-1 functions regulate key aspects of the innate immune response. Plos One. 8: e69539. PMID 23894499 DOI: 10.1371/journal.pone.0069539  1
2013 Aylsworth CF, Aldhamen YA, Seregin SS, Godbehere S, Amalfitano A. Activation of human natural killer cells by the novel innate immune modulator recombinant Eimeria antigen. Human Immunology. 74: 916-26. PMID 23639554 DOI: 10.1016/j.humimm.2013.04.035  1
2012 Evnouchidou I, Birtley J, Seregin S, Papakyriakou A, Zervoudi E, Samiotaki M, Panayotou G, Giastas P, Petrakis O, Georgiadis D, Amalfitano A, Saridakis E, Mavridis IM, Stratikos E. A common single nucleotide polymorphism in endoplasmic reticulum aminopeptidase 2 induces a specificity switch that leads to altered antigen processing. Journal of Immunology (Baltimore, Md. : 1950). 189: 2383-92. PMID 22837489 DOI: 10.4049/jimmunol.1200918  1
2012 Aldhamen YA, Seregin SS, Schuldt NJ, Rastall DP, Liu CJ, Godbehere S, Amalfitano A. Vaccines expressing the innate immune modulator EAT-2 elicit potent effector memory T lymphocyte responses despite pre-existing vaccine immunity. Journal of Immunology (Baltimore, Md. : 1950). 189: 1349-59. PMID 22745373 DOI: 10.4049/jimmunol.1200736  1
2012 Schuldt NJ, Aldhamen YA, Godbehere-Roosa S, Seregin SS, Kousa YA, Amalfitano A. Immunogenicity when utilizing adenovirus serotype 4 and 5 vaccines expressing circumsporozoite protein in naïve and adenovirus (Ad5) immune mice. Malaria Journal. 11: 209. PMID 22720732 DOI: 10.1186/1475-2875-11-209  1
2012 Seregin SS, Aldhamen YA, Rastall DP, Godbehere S, Amalfitano A. Adenovirus-based vaccination against Clostridium difficile toxin A allows for rapid humoral immunity and complete protection from toxin A lethal challenge in mice. Vaccine. 30: 1492-501. PMID 22200503 DOI: 10.1016/j.vaccine.2011.12.064  1
2011 Aldhamen YA, Seregin SS, Amalfitano A. Immune recognition of gene transfer vectors: focus on adenovirus as a paradigm. Frontiers in Immunology. 2: 40. PMID 22566830 DOI: 10.3389/fimmu.2011.00040  1
2011 Schuldt NJ, Aldhamen YA, Appledorn DM, Seregin SS, Kousa Y, Godbehere S, Amalfitano A. Vaccine platforms combining circumsporozoite protein and potent immune modulators, rEA or EAT-2, paradoxically result in opposing immune responses. Plos One. 6: e24147. PMID 21912619 DOI: 10.1371/journal.pone.0024147  1
2011 Seregin SS, Amalfitano A. Gene therapy for lysosomal storage diseases: progress, challenges and future prospects. Current Pharmaceutical Design. 17: 2558-74. PMID 21774776 DOI: 10.2174/138161211797247578  1
2011 Seregin SS, Aldhamen YA, Appledorn DM, Aylsworth CF, Godbehere S, Liu CJ, Quiroga D, Amalfitano A. TRIF is a critical negative regulator of TLR agonist mediated activation of dendritic cells in vivo. Plos One. 6: e22064. PMID 21760953 DOI: 10.1371/journal.pone.0022064  1
2011 Seregin SS, Aldhamen YA, Appledorn DM, Zehnder J, Voss T, Godbehere S, Amalfitano A. Use of DAF-displaying adenovirus vectors reduces induction of transgene- and vector-specific adaptive immune responses in mice. Human Gene Therapy. 22: 1083-94. PMID 21388344 DOI: 10.1089/hum.2010.218  1
2011 Evnouchidou I, Kamal RP, Seregin SS, Goto Y, Tsujimoto M, Hattori A, Voulgari PV, Drosos AA, Amalfitano A, York IA, Stratikos E. Cutting Edge: Coding single nucleotide polymorphisms of endoplasmic reticulum aminopeptidase 1 can affect antigenic peptide generation in vitro by influencing basic enzymatic properties of the enzyme. Journal of Immunology (Baltimore, Md. : 1950). 186: 1909-13. PMID 21242517 DOI: 10.4049/jimmunol.1003337  1
2011 Aldhamen YA, Appledorn DM, Seregin SS, Liu CJ, Schuldt NJ, Godbehere S, Amalfitano A. Expression of the SLAM family of receptors adapter EAT-2 as a novel strategy for enhancing beneficial immune responses to vaccine antigens. Journal of Immunology (Baltimore, Md. : 1950). 186: 722-32. PMID 21149608 DOI: 10.4049/jimmunol.1002105  1
2011 Appledorn DM, Aldhamen YA, Godbehere S, Seregin SS, Amalfitano A. Sublingual administration of an adenovirus serotype 5 (Ad5)-based vaccine confirms Toll-like receptor agonist activity in the oral cavity and elicits improved mucosal and systemic cell-mediated responses against HIV antigens despite preexisting Ad5 immunity. Clinical and Vaccine Immunology : Cvi. 18: 150-60. PMID 21084461 DOI: 10.1128/CVI.00341-10  1
2010 Seregin SS, Amalfitano A. Improving adenovirus based gene transfer: strategies to accomplish immune evasion. Viruses. 2: 2013-36. PMID 21994718 DOI: 10.3390/v2092013  1
2010 Seregin SS, Aldhamen YA, Appledorn DM, Hartman ZC, Schuldt NJ, Scott J, Godbehere S, Jiang H, Frank MM, Amalfitano A. Adenovirus capsid-display of the retro-oriented human complement inhibitor DAF reduces Ad vector-triggered immune responses in vitro and in vivo. Blood. 116: 1669-77. PMID 20511542 DOI: 10.1182/blood-2010-03-276949  1
2010 Seregin SS, Hartman ZC, Appledorn DM, Godbehere S, Jiang H, Frank MM, Amalfitano A. Novel adenovirus vectors 'capsid-displaying' a human complement inhibitor. Journal of Innate Immunity. 2: 353-9. PMID 20375551 DOI: 10.1159/000284368  1
2010 Appledorn DM, Aldhamen YA, Depas W, Seregin SS, Liu CJ, Schuldt N, Quach D, Quiroga D, Godbehere S, Zlatkin I, Kim S, McCormick JJ, Amalfitano A. A new adenovirus based vaccine vector expressing an Eimeria tenella derived TLR agonist improves cellular immune responses to an antigenic target. Plos One. 5: e9579. PMID 20221448 DOI: 10.1371/journal.pone.0009579  1
2010 Seregin SS, Appledorn DM, Patial S, Bujold M, Nance W, Godbehere S, Parameswaran N, Amalfitano A. beta-Arrestins modulate Adenovirus-vector-induced innate immune responses: differential regulation by beta-arrestin-1 and beta-arrestin-2. Virus Research. 147: 123-34. PMID 19896992 DOI: 10.1016/j.virusres.2009.10.023  1
2009 Seregin SS, Amalfitano A. Overcoming pre-existing adenovirus immunity by genetic engineering of adenovirus-based vectors. Expert Opinion On Biological Therapy. 9: 1521-31. PMID 19780714 DOI: 10.1517/14712590903307388  1
2009 Seregin SS, Aldhamen YA, Appledorn DM, Schuldt NJ, McBride AJ, Bujold M, Godbehere SS, Amalfitano A. CR1/2 is an important suppressor of Adenovirus-induced innate immune responses and is required for induction of neutralizing antibodies. Gene Therapy. 16: 1245-59. PMID 19554032 DOI: 10.1038/gt.2009.77  1
2009 Seregin SS, Appledorn DM, McBride AJ, Schuldt NJ, Aldhamen YA, Voss T, Wei J, Bujold M, Nance W, Godbehere S, Amalfitano A. Transient pretreatment with glucocorticoid ablates innate toxicity of systemically delivered adenoviral vectors without reducing efficacy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 685-96. PMID 19174760 DOI: 10.1038/mt.2008.297  1
2008 Appledorn DM, McBride A, Seregin S, Scott JM, Schuldt N, Kiang A, Godbehere S, Amalfitano A. Complex interactions with several arms of the complement system dictate innate and humoral immunity to adenoviral vectors. Gene Therapy. 15: 1606-17. PMID 18615115 DOI: 10.1038/gt.2008.114  1
2008 Appledorn DM, Seregin S, Amalfitano A. Adenovirus vectors for renal-targeted gene delivery. Contributions to Nephrology. 159: 47-62. PMID 18391584 DOI: 10.1159/000125581  1
2008 Appledorn DM, Kiang A, McBride A, Jiang H, Seregin S, Scott JM, Stringer R, Kousa Y, Hoban M, Frank MM, Amalfitano A. Wild-type adenoviruses from groups A-F evoke unique innate immune responses, of which HAd3 and SAd23 are partially complement dependent. Gene Therapy. 15: 885-901. PMID 18288208 DOI: 10.1038/gt.2008.18  1
2005 Ilyichev AA, Karpenko LI, Nekrasova NA, Lebedev LR, Ignatev GM, Agafonov AP, Belavin PA, Seregin SS, Danilyuk NK, Bazhan SI. DIfferent systems of delivery of HIV-1 DNA vaccine encoding the multiepitope CTL-immunogene Vestnik Rossiiskoi Akademii Meditsinskikh Nauk. 41-44. PMID 15715155  1
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