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Adam R. Hersperger, Ph.D. - Publications

Affiliations: 
2010 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Microbiology Biology, Immunology
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17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Forsyth KS, Roy NH, Peauroi E, DeHaven BC, Wold ED, Hersperger AR, Burkhardt JK, Eisenlohr LC. Ectromelia-encoded virulence factor C15 specifically inhibits antigen presentation to CD4+ T cells post peptide loading. Plos Pathogens. 16: e1008685. PMID 32745153 DOI: 10.1371/Journal.Ppat.1008685  0.709
2018 Magee MS, Abraham TS, Baybutt TR, Flickinger JC, Ridge NA, Marszalowicz GP, Prajapati P, Hersperger AR, Waldman SA, Snook AE. Human GUCY2C-targeted chimeric antigen receptor (CAR)-expressing T cells eliminate colorectal cancer metastases. Cancer Immunology Research. PMID 29615399 DOI: 10.1158/2326-6066.Cir-16-0362  0.515
2018 Frey TR, Forsyth KS, Sheehan MM, De Haven BC, Pevarnik JG, Hand ES, Pizzorno MC, Eisenlohr LC, Hersperger AR. Ectromelia virus lacking the E3L ortholog is replication-defective and nonpathogenic but does induce protective immunity in a mouse strain susceptible to lethal mousepox. Virology. 518: 335-348. PMID 29602068 DOI: 10.1016/J.Virol.2018.03.016  0.345
2017 Frey TR, Lehmann MH, Ryan CM, Pizzorno MC, Sutter G, Hersperger AR. Ectromelia virus accumulates less double-stranded RNA compared to vaccinia virus in BS-C-1 cells. Virology. 509: 98-111. PMID 28628829 DOI: 10.1016/J.Virol.2017.06.010  0.347
2015 Hand ES, Haller SL, Peng C, Rothenburg S, Hersperger AR. Ectopic expression of vaccinia virus E3 and K3 cannot rescue ectromelia virus replication in rabbit RK13 cells. Plos One. 10: e0119189. PMID 25734776 DOI: 10.1371/Journal.Pone.0119189  0.408
2014 Siciliano NA, Hersperger AR, Lacuanan AM, Xu RH, Sidney J, Sette A, Sigal LJ, Eisenlohr LC. Impact of distinct poxvirus infections on the specificities and functionalities of CD4+ T cell responses. Journal of Virology. 88: 10078-91. PMID 24965457 DOI: 10.1128/Jvi.01150-14  0.558
2014 Hersperger AR, Siciliano NA, DeHaven BC, Snook AE, Eisenlohr LC. Epithelial immunization induces polyfunctional CD8+ T cells and optimal mousepox protection. Journal of Virology. 88: 9472-5. PMID 24899206 DOI: 10.1128/Jvi.01464-14  0.604
2013 Magee MS, Snook AE, Hersperger AR, Marszalowicz GP, Waldman SA. GUCY2C-targeted chimeric antigen receptor expressing T cells extend survival in a therapeutic mouse model of metastatic colorectal cancer Journal For Immunotherapy of Cancer. 1. DOI: 10.1186/2051-1426-1-S1-P22  0.582
2012 Fang M, Siciliano NA, Hersperger AR, Roscoe F, Hu A, Ma X, Shamsedeen AR, Eisenlohr LC, Sigal LJ. Perforin-dependent CD4+ T-cell cytotoxicity contributes to control a murine poxvirus infection. Proceedings of the National Academy of Sciences of the United States of America. 109: 9983-8. PMID 22665800 DOI: 10.1073/Pnas.1202143109  0.727
2012 Hersperger AR, Siciliano NA, Eisenlohr LC. Comparable polyfunctionality of ectromelia virus- and vaccinia virus-specific murine T cells despite markedly different in vivo replication and pathogenicity. Journal of Virology. 86: 7298-309. PMID 22532670 DOI: 10.1128/Jvi.00038-12  0.652
2011 Hersperger AR, Migueles SA, Betts MR, Connors M. Qualitative features of the HIV-specific CD8+ T-cell response associated with immunologic control. Current Opinion in Hiv and Aids. 6: 169-73. PMID 21399496 DOI: 10.1097/Coh.0B013E3283454C39  0.695
2011 Hersperger AR, Martin JN, Shin LY, Sheth PM, Kovacs CM, Cosma GL, Makedonas G, Pereyra F, Walker BD, Kaul R, Deeks SG, Betts MR. Increased HIV-specific CD8+ T-cell cytotoxic potential in HIV elite controllers is associated with T-bet expression. Blood. 117: 3799-808. PMID 21289310 DOI: 10.1182/Blood-2010-12-322727  0.758
2010 Hersperger AR, Pereyra F, Nason M, Demers K, Sheth P, Shin LY, Kovacs CM, Rodriguez B, Sieg SF, Teixeira-Johnson L, Gudonis D, Goepfert PA, Lederman MM, Frank I, Makedonas G, et al. Perforin expression directly ex vivo by HIV-specific CD8 T-cells is a correlate of HIV elite control. Plos Pathogens. 6: e1000917. PMID 20523897 DOI: 10.1371/Journal.Ppat.1000917  0.73
2010 Makedonas G, Hutnick N, Haney D, Amick AC, Gardner J, Cosma G, Hersperger AR, Dolfi D, Wherry EJ, Ferrari G, Betts MR. Perforin and IL-2 upregulation define qualitative differences among highly functional virus-specific human CD8 T cells. Plos Pathogens. 6: e1000798. PMID 20221423 DOI: 10.1371/Journal.Ppat.1000798  0.603
2009 Makedonas G, Banerjee PP, Pandey R, Hersperger AR, Sanborn KB, Hardy GA, Orange JS, Betts MR. Rapid up-regulation and granule-independent transport of perforin to the immunological synapse define a novel mechanism of antigen-specific CD8+ T cell cytotoxic activity. Journal of Immunology (Baltimore, Md. : 1950). 182: 5560-9. PMID 19380804 DOI: 10.4049/Jimmunol.0803945  0.747
2009 Hersperger AR, Pereyra F, Demers K, Sheth P, Shin LY, Rodriguez B, Sieg SF, Teixeira-Johnson L, Goepfert PA, Lederman MM, Kaul R, Makedonas G, Walker BD, Betts MR. S03-06 OA. Rapid perforin upregulation by CD8 T cells in elite controllers as a correlate of immune-mediated control of HIV replication Retrovirology. 6: O45. DOI: 10.1186/1742-4690-6-S3-O45  0.737
2008 Hersperger AR, Makedonas G, Betts MR. Flow cytometric detection of perforin upregulation in human CD8 T cells. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 73: 1050-7. PMID 18615597 DOI: 10.1002/Cyto.A.20596  0.754
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