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Natalie A. Hutnick, Ph.D. - Publications

Affiliations: 
2010 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Immunology, Virology Biology
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25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Scott VL, Villarreal DO, Hutnick NA, Walters JN, Ragwan E, Bdeir K, Yan J, Sardesai NY, Finnefrock AC, Casimiro DR, Weiner DB. DNA vaccines targeting heavy chain C-terminal fragments of Clostridium botulinum neurotoxin serotypes A, B, and E induce potent humoral and cellular immunity and provide protection from lethal toxin challenge. Human Vaccines & Immunotherapeutics. 11: 1961-71. PMID 26158319 DOI: 10.1080/21645515.2015.1066051  0.46
2015 Wise MC, Hutnick NA, Pollara J, Myles DJ, Williams C, Yan J, LaBranche CC, Khan AS, Sardesai NY, Montefiori D, Barnett SW, Zolla-Pazner S, Ferrari G, Weiner DB. An enhanced synthetic multi-clade DNA prime induces improved cross-clade reactive functional antibodies when combined with an adjuvanted protein boost in non-human primates. Journal of Virology. PMID 26085155 DOI: 10.1128/Jvi.00652-15  0.512
2015 Kutzler MA, Wise MC, Hutnick NA, Moldoveanu Z, Hunter M, Reuter MA, Yuan S, Yan J, Ginsberg AA, Sylvester A, Pahar B, Carnathan DG, Kathuria N, Khan AS, Montefiori D, et al. Chemokine-adjuvanted electroporated DNA vaccine induces substantial protection from simian immunodeficiency virus vaginal challenge. Mucosal Immunology. PMID 25943275 DOI: 10.1038/Mi.2015.31  0.616
2014 Shedlock DJ, Tingey C, Mahadevan L, Hutnick N, Reuschel EL, Kudchodkar S, Flingai S, Yan J, Kim JJ, Ugen KE, Weiner DB, Muthumani K. Co-Administration of Molecular Adjuvants Expressing NF-Kappa B Subunit p65/RelA or Type-1 Transactivator T-bet Enhance Antigen Specific DNA Vaccine-Induced Immunity. Vaccines. 2: 196-215. PMID 26344618 DOI: 10.3390/Vaccines2020196  0.512
2013 Muthumani K, Wise MC, Broderick KE, Hutnick N, Goodman J, Flingai S, Yan J, Bian CB, Mendoza J, Tingey C, Wilson C, Wojtak K, Sardesai NY, Weiner DB. HIV-1 Env DNA vaccine plus protein boost delivered by EP expands B- and T-cell responses and neutralizing phenotype in vivo. Plos One. 8: e84234. PMID 24391921 DOI: 10.1371/Journal.Pone.0084234  0.45
2013 Obeng-Adjei N, Hutnick NA, Yan J, Chu JS, Myles DJ, Morrow MP, Sardesai NY, Weiner DB. DNA vaccine cocktail expressing genotype A and C HBV surface and consensus core antigens generates robust cytotoxic and antibody responses in mice and Rhesus macaques. Cancer Gene Therapy. 20: 652-62. PMID 24310062 DOI: 10.1038/Cgt.2013.65  0.469
2013 Ferraro B, Talbott KT, Balakrishnan A, Cisper N, Morrow MP, Hutnick NA, Myles DJ, Shedlock DJ, Obeng-Adjei N, Yan J, Kayatani AK, Richie N, Cabrera W, Shiver R, Khan AS, et al. Inducing humoral and cellular responses to multiple sporozoite and liver-stage malaria antigens using exogenous plasmid DNA. Infection and Immunity. 81: 3709-20. PMID 23897618 DOI: 10.1128/Iai.00180-13  0.524
2012 Hutnick NA, Myles DJ, Ferraro B, Lucke C, Lin F, Yan J, Broderick KE, Khan AS, Sardesai NY, Weiner DB. Intradermal DNA vaccination enhanced by low-current electroporation improves antigen expression and induces robust cellular and humoral immune responses. Human Gene Therapy. 23: 943-50. PMID 22650607 DOI: 10.1089/Hum.2012.055  0.46
2012 Hutnick NA, Myles DJ, Hirao L, Scott VL, Ferraro B, Khan AS, Lewis MG, Miller CJ, Bett AJ, Casimiro D, Sardesai NY, Kim JJ, Shiver J, Weiner DB. An optimized SIV DNA vaccine can serve as a boost for Ad5 and provide partial protection from a high-dose SIVmac251 challenge. Vaccine. 30: 3202-8. PMID 22406458 DOI: 10.1016/J.Vaccine.2012.02.069  0.592
2012 Hutnick N, Karuppiah M, Pollara J, Yan J, Myles D, Broderick K, Morrow M, Sardasai N, Montefiori D, Barnett S, Ferrari G, Weiner D. E-DNA IM or ID delivery prime enhances antibody and T cell responses following recombinant gp120 env boost Retrovirology. 9: 364. DOI: 10.1186/1742-4690-9-S2-P364  0.532
2012 Hutnick N, Myles D, Ginsberg A, Khan A, Yan J, Moldoveanu Z, Mestecky J, Marx P, Kutzler M, Weiner D. Improved systemic and mucosal antibody responses with a CCR10 ligand adjuvant Retrovirology. 9: 203. DOI: 10.1186/1742-4690-9-S2-P203  0.45
2012 Hutnick N, Myles D, Muthumani K, Morrow M, Yan J, Khan A, Sardasai N, Weiner D. Robust antibody and cellular responses with an improved DNA vaccine alone Retrovirology. 9: 15. DOI: 10.1186/1742-4690-9-S2-P15  0.518
2012 Sardesai N, Khan A, McCoy J, Lin F, Mendoza J, Yang M, Yan J, Hutnick N, Muthumani K, Weiner D, Broderick K. Minimally invasive and surface electroporation delivery of DNA vaccines for the induction of robust humoral immune responses against HIV antigens Retrovirology. 9: 1-1. DOI: 10.1186/1742-4690-9-S2-O9  0.464
2011 Hutnick NA, Myles DJ, Bian CB, Muthumani K, Weiner DB. Selected approaches for increasing HIV DNA vaccine immunogenicity in vivo. Current Opinion in Virology. 1: 233-40. PMID 22440782 DOI: 10.1016/J.Coviro.2011.08.003  0.43
2011 Ferraro B, Morrow MP, Hutnick NA, Shin TH, Lucke CE, Weiner DB. Clinical applications of DNA vaccines: current progress. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 53: 296-302. PMID 21765081 DOI: 10.1093/Cid/Cir334  0.437
2010 Hutnick NA, Carnathan DG, Dubey SA, Cox KS, Kierstead L, Makadonas G, Ratcliffe SJ, Lasaro MO, Robertson MN, Casimiro DR, Ertl HC, Betts MR. Vaccination with Ad5 vectors expands Ad5-specific CD8 T cells without altering memory phenotype or functionality. Plos One. 5: e14385. PMID 21203546 DOI: 10.1371/Journal.Pone.0014385  0.746
2010 Chen H, Xiang ZQ, Li Y, Kurupati RK, Jia B, Bian A, Zhou DM, Hutnick N, Yuan S, Gray C, Serwanga J, Auma B, Kaleebu P, Zhou X, Betts MR, et al. Adenovirus-based vaccines: comparison of vectors from three species of adenoviridae. Journal of Virology. 84: 10522-32. PMID 20686035 DOI: 10.1128/Jvi.00450-10  0.688
2010 Makedonas G, Hutnick N, Haney D, Amick AC, Gardner J, Cosma G, Hersperger AR, Dolfi D, Wherry EJ, Ferrari G, Betts MR. Perforin and IL-2 upregulation define qualitative differences among highly functional virus-specific human CD8 T cells. Plos Pathogens. 6: e1000798. PMID 20221423 DOI: 10.1371/Journal.Ppat.1000798  0.613
2010 Hutnick NA, Carnathan D, Demers K, Makedonas G, Ertl HC, Betts MR. Adenovirus-specific human T cells are pervasive, polyfunctional, and cross-reactive. Vaccine. 28: 1932-41. PMID 20188249 DOI: 10.1016/J.Vaccine.2009.10.091  0.743
2009 Hutnick NA, Carnathan DG, Dubey SA, Makedonas G, Cox KS, Kierstead L, Ratcliffe SJ, Robertson MN, Casimiro DR, Ertl HC, Betts MR. Baseline Ad5 serostatus does not predict Ad5 HIV vaccine-induced expansion of adenovirus-specific CD4+ T cells. Nature Medicine. 15: 876-8. PMID 19620962 DOI: 10.1038/Nm.1989  0.723
2009 O'Brien KL, Liu J, King SL, Sun YH, Schmitz JE, Lifton MA, Hutnick NA, Betts MR, Dubey SA, Goudsmit J, Shiver JW, Robertson MN, Casimiro DR, Barouch DH. Adenovirus-specific immunity after immunization with an Ad5 HIV-1 vaccine candidate in humans. Nature Medicine. 15: 873-5. PMID 19620961 DOI: 10.1038/Nm.1991  0.685
2009 Mingozzi F, Meulenberg JJ, Hui DJ, Basner-Tschakarjan E, Hasbrouck NC, Edmonson SA, Hutnick NA, Betts MR, Kastelein JJ, Stroes ES, High KA. AAV-1-mediated gene transfer to skeletal muscle in humans results in dose-dependent activation of capsid-specific T cells. Blood. 114: 2077-86. PMID 19506302 DOI: 10.1182/Blood-2008-07-167510  0.634
2009 Hutnick N, Carnathan D, Dubey S, Cox K, Ratcliffe S, Robertson MN, Casimiro DR, Ertl HC, Betts MR. P16-09. Adenovirus 5 vector HIV vaccination does not affect mucosal homing markers on Ad5-specific CD4+ T-cells in humans Retrovirology. 6: P238. DOI: 10.1186/1742-4690-6-S3-P238  0.715
2009 Hutnick NA, Carnathan DG, Dubey SA, Makedonas G, Cox KS, Kierstead L, Ratcliffe SJ, Robertson MN, Casimiro DR, Ertl HCJ, Betts MR. Erratum: Corrigendum: Baseline Ad5 serostatus does not predict Ad5 HIV vaccine–induced expansion of adenovirus-specific CD4+ T cells Nature Medicine. 15: 1333-1333. DOI: 10.1038/Nm1109-1333B  0.694
2007 Vonderheide RH, Flaherty KT, Khalil M, Stumacher MS, Bajor DL, Hutnick NA, Sullivan P, Mahany JJ, Gallagher M, Kramer A, Green SJ, O'Dwyer PJ, Running KL, Huhn RD, Antonia SJ. Clinical activity and immune modulation in cancer patients treated with CP-870,893, a novel CD40 agonist monoclonal antibody. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 25: 876-83. PMID 17327609 DOI: 10.1200/Jco.2006.08.3311  0.368
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