Richard P. Darveau - Publications

Affiliations: 
University of Washington, Seattle, Seattle, WA 
Area:
Dentistry, Microbiology Biology

111 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Kerns KA, Bamashmous S, Hendrickson EL, Kotsakis GA, Leroux BG, Daubert DD, Roberts FA, Chen D, Trivedi HM, Darveau RP, McLean JS. Localized microbially induced inflammation influences distant healthy tissues in the human oral cavity. Proceedings of the National Academy of Sciences of the United States of America. 120: e2306020120. PMID 37782795 DOI: 10.1073/pnas.2306020120  0.359
2022 Zenobia C, Darveau RP. Does Oral Endotoxin Contribute to Systemic Inflammation? Frontiers in Oral Health. 3: 911420. PMID 35677024 DOI: 10.3389/froh.2022.911420  0.78
2022 Kantrong N, Chang AM, Bamashmous S, Hajjar AM, Bucula RJ, Darveau RP. Macrophage migration inhibitory factor regulates specific innate immune sensor responses in gingival epithelial cells. Journal of Periodontology. PMID 35100435 DOI: 10.1002/JPER.21-0598  0.312
2021 Kordahi MC, Stanaway IB, Avril M, Chac D, Blanc MP, Ross B, Diener C, Jain S, McCleary P, Parker A, Friedman V, Huang J, Burke W, Gibbons SM, Willis AD, ... Darveau RP, et al. Genomic and functional characterization of a mucosal symbiont involved in early-stage colorectal cancer. Cell Host & Microbe. PMID 34536346 DOI: 10.1016/j.chom.2021.08.013  0.303
2021 Bamashmous S, Kotsakis GA, Kerns KA, Leroux BG, Zenobia C, Chen D, Trivedi HM, McLean JS, Darveau RP. Human variation in gingival inflammation. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34193520 DOI: 10.1073/pnas.2012578118  0.791
2021 Herath TDK, Darveau RP, Seneviratne CJ, Wang CY, Wang Y, Jin L. Author Correction: Heterogeneous Porphyromonas gingivalis LPS modulates immuno-inflammatory response, antioxidant defense and cytoskeletal dynamics in human gingival fibroblasts. Scientific Reports. 11: 2337. PMID 33483549 DOI: 10.1038/s41598-021-81798-0  0.34
2020 Papadopoulos G, Berland R, Sunkavalli A, Coats SR, Darveau RP, Genco CA. Microbial lipid A remodeling controls cross-presentation efficiency and CD8 T cell priming by modulating dendritic cell function. Infection and Immunity. PMID 33257533 DOI: 10.1128/IAI.00335-20  0.467
2020 Kamarajan P, Ateia I, Shin JM, Fenno JC, Le C, Zhan L, Chang A, Darveau R, Kapila YL. Periodontal pathogens promote cancer aggressivity via TLR/MyD88 triggered activation of Integrin/FAK signaling that is therapeutically reversible by a probiotic bacteriocin. Plos Pathogens. 16: e1008881. PMID 33002094 DOI: 10.1371/journal.ppat.1008881  0.306
2019 Grevich S, Lee P, Leroux B, Ringold S, Darveau R, Henstorf G, Berg J, Kim A, Velan E, Kelly J, Baltuck C, Reeves A, Leahey H, Hager K, Brittnacher M, et al. Oral health and plaque microbial profile in juvenile idiopathic arthritis. Pediatric Rheumatology Online Journal. 17: 81. PMID 31842923 DOI: 10.1186/S12969-019-0387-5  0.327
2019 Kantrong N, To TT, Darveau RP. Gingival Epithelial Cell Recognition of Lipopolysaccharide. Advances in Experimental Medicine and Biology. 1197: 55-67. PMID 31732934 DOI: 10.1007/978-3-030-28524-1_5  0.526
2019 Coats SR, Kantrong N, To TT, Jain S, Genco CA, McLean JS, Darveau RP. The distinct immune-stimulatory capacities of strains 381 and ATCC 33277 are determined by the allele and gingipain activity. Infection and Immunity. PMID 31570556 DOI: 10.1128/Iai.00319-19  0.387
2019 Chang AM, Liu Q, Hajjar AM, Greer A, McLean JS, Darveau RP. Toll-like receptor 2 and toll-like receptor 4 responses regulate neutrophil infiltration into the junctional epithelium and significantly contribute to the composition of the oral microbiota. Journal of Periodontology. PMID 31111967 DOI: 10.1002/Jper.18-0719  0.422
2019 Jain S, Chang AM, Singh M, McLean JS, Coats SR, Kramer RW, Darveau RP. Identification of PGN_1123 as the gene encoding lipid A deacylase, an enzyme required for Toll-like receptor 4 evasion, in . Journal of Bacteriology. PMID 30782639 DOI: 10.1128/Jb.00683-18  0.549
2018 Marinho ACS, To TT, Darveau RP, Gomes BPFA. Detection and function of lipopolysaccharide and its purified lipid A after treatment with auxiliary chemical substances and calcium hydroxide dressings used in root canal treatment. International Endodontic Journal. PMID 29505121 DOI: 10.1111/Iej.12920  0.388
2017 Kajiwara K, Takata S, To TT, Takara K, Hatakeyama Y, Tamaoki S, Darveau RP, Ishikawa H, Sawa Y. The promotion of nephropathy by Porphyromonas gingivalis lipopolysaccharide via toll-like receptors. Diabetology & Metabolic Syndrome. 9: 73. PMID 29018490 DOI: 10.1186/S13098-017-0271-8  0.387
2017 Ding PH, Darveau RP, Wang CY, Jin L. 3LPS-binding protein and its interactions with P. gingivalis LPS modulate pro-inflammatory response and Toll-like receptor signaling in human oral keratinocytes. Plos One. 12: e0173223. PMID 28384159 DOI: 10.1371/Journal.Pone.0173223  0.486
2016 Biswas K, Chang A, Hoggard M, Radcliff FJ, Jiang Y, Taylor MW, Darveau R, Douglas RG. Toll-like receptor activation by sino-nasal mucus in chronic rhinosinusitis. Rhinology. PMID 28025987 DOI: 10.4193/Rhin16.201  0.303
2016 Herath TD, Darveau RP, Seneviratne CJ, Wang CY, Wang Y, Jin L. Heterogeneous Porphyromonas gingivalis LPS modulates immuno-inflammatory response, antioxidant defense and cytoskeletal dynamics in human gingival fibroblasts. Scientific Reports. 6: 29829. PMID 27538450 DOI: 10.1038/Srep29829  0.476
2016 Coats SR, Hashim A, Paramonov NA, To TT, Curtis MA, Darveau RP. Cardiolipins Act as a Selective Barrier to Toll-Like Receptor 4 Activation in the Intestine. Applied and Environmental Microbiology. PMID 27208127 DOI: 10.1128/Aem.00463-16  0.549
2016 Martinho FC, Leite FR, Nóbrega LM, Endo MS, Nascimento GG, Darveau RP, Gomes BP. Comparison of Fusobacterium nucleatum and Porphyromonas gingivalis Lipopolysaccharides Clinically Isolated from Root Canal Infection in the Induction of Pro-Inflammatory Cytokines Secretion. Brazilian Dental Journal. 27: 202-7. PMID 27058385 DOI: 10.1590/0103-6440201600572  0.406
2016 Jain R, Waldvogel-Thurlow S, Darveau R, Douglas R. Differences in the paranasal sinuses between germ-free and pathogen-free mice. International Forum of Allergy & Rhinology. PMID 27028583 DOI: 10.1002/Alr.21712  0.337
2016 Greer A, Irie K, Hashim A, Leroux BG, Chang AM, Curtis MA, Darveau RP. Site-Specific Neutrophil Migration and CXCL2 Expression in Periodontal Tissue. Journal of Dental Research. PMID 27013641 DOI: 10.1177/0022034516641036  0.406
2015 To TT, Gümüş P, Nizam N, Buduneli N, Darveau RP. Subgingival Plaque in Periodontal Health Antagonizes at Toll-Like Receptor 4 and Inhibits E-Selectin Expression on Endothelial Cells. Infection and Immunity. 84: 120-6. PMID 26483407 DOI: 10.1128/Iai.00693-15  0.478
2015 Roberts FA, Darveau RP. Microbial protection and virulence in periodontal tissue as a function of polymicrobial communities: symbiosis and dysbiosis. Periodontology 2000. 69: 18-27. PMID 26252399 DOI: 10.1111/Prd.12087  0.394
2015 Irie K, Tomofuji T, Ekuni D, Morita M, Shimazaki Y, Darveau RP. Impact of Oral Commensal Bacteria on Degradation of Periodontal Connective Tissue in Mice. Journal of Periodontology. 86: 899-905. PMID 25879792 DOI: 10.1902/Jop.2015.150006  0.418
2014 Muthukuru M, Darveau RP. TLR signaling that induces weak inflammatory response and SHIP1 enhances osteogenic functions. Bone Research. 2: 14031. PMID 26273527 DOI: 10.1038/Boneres.2014.31  0.485
2014 Slocum C, Coats SR, Hua N, Kramer C, Papadopoulos G, Weinberg EO, Gudino CV, Hamilton JA, Darveau RP, Genco CA. Distinct lipid a moieties contribute to pathogen-induced site-specific vascular inflammation. Plos Pathogens. 10: e1004215. PMID 25010102 DOI: 10.1371/Journal.Ppat.1004215  0.535
2014 Darveau RP. Porphyromonas gingivalis neutrophil manipulation: risk factor for periodontitis? Trends in Microbiology. 22: 428-9. PMID 25001854 DOI: 10.1016/J.Tim.2014.06.006  0.375
2014 Zenobia C, Hasturk H, Nguyen D, Van Dyke TE, Kantarci A, Darveau RP. Porphyromonas gingivalis lipid A phosphatase activity is critical for colonization and increasing the commensal load in the rabbit ligature model. Infection and Immunity. 82: 650-9. PMID 24478080 DOI: 10.1128/Iai.01136-13  0.823
2014 Nogueira-Filho G, Rosa BT, Santos PF, Tunes UR, Freire SM, Meyer R, Darveau RP. Whole-blood cultures from patients with chronic periodontitis respond differently to Porphyromonas gingivalis but not Escherichia coli lipopolysaccharide. Journal of Periodontology. 85: e18-23. PMID 24001045 DOI: 10.1902/Jop.2013.120735  0.465
2013 Thomas L, Bielemeier A, Lambert PA, Darveau RP, Marshall LJ, Devitt A. The N-terminus of CD14 acts to bind apoptotic cells and confers rapid-tethering capabilities on non-myeloid cells. Plos One. 8: e70691. PMID 23936239 DOI: 10.1371/Journal.Pone.0070691  0.323
2013 Greer A, Zenobia C, Darveau RP. Defensins and LL-37: a review of function in the gingival epithelium. Periodontology 2000. 63: 67-79. PMID 23931055 DOI: 10.1111/Prd.12028  0.782
2013 Chilton PM, Hadel DM, To TT, Mitchell TC, Darveau RP. Adjuvant activity of naturally occurring monophosphoryl lipopolysaccharide preparations from mucosa-associated bacteria. Infection and Immunity. 81: 3317-25. PMID 23798540 DOI: 10.1128/Iai.01150-12  0.505
2013 Herath TD, Darveau RP, Seneviratne CJ, Wang CY, Wang Y, Jin L. Tetra- and penta-acylated lipid A structures of Porphyromonas gingivalis LPS differentially activate TLR4-mediated NF-κB signal transduction cascade and immuno-inflammatory response in human gingival fibroblasts. Plos One. 8: e58496. PMID 23554896 DOI: 10.1371/Journal.Pone.0058496  0.543
2013 Herath TD, Wang Y, Seneviratne CJ, Darveau RP, Wang CY, Jin L. The expression and regulation of matrix metalloproteinase-3 is critically modulated by Porphyromonas gingivalis lipopolysaccharide with heterogeneous lipid A structures in human gingival fibroblasts. Bmc Microbiology. 13: 73. PMID 23548063 DOI: 10.1186/1471-2180-13-73  0.478
2013 Zenobia C, Luo XL, Hashim A, Abe T, Jin L, Chang Y, Jin ZC, Sun JX, Hajishengallis G, Curtis MA, Darveau RP. Commensal bacteria-dependent select expression of CXCL2 contributes to periodontal tissue homeostasis. Cellular Microbiology. 15: 1419-26. PMID 23433011 DOI: 10.1111/Cmi.12127  0.784
2013 Jain S, Coats SR, Chang AM, Darveau RP. A novel class of lipoprotein lipase-sensitive molecules mediates Toll-like receptor 2 activation by Porphyromonas gingivalis. Infection and Immunity. 81: 1277-86. PMID 23381996 DOI: 10.1128/Iai.01036-12  0.531
2013 Ding PH, Wang CY, Darveau RP, Jin LJ. Nuclear factor-κB and p38 mitogen-activated protein kinase signaling pathways are critically involved in Porphyromonas gingivalis lipopolysaccharide induction of lipopolysaccharide-binding protein expression in human oral keratinocytes. Molecular Oral Microbiology. 28: 129-41. PMID 23194012 DOI: 10.1111/Omi.12010  0.496
2013 Ding PH, Wang CY, Darveau RP, Jin L. Porphyromonas gingivalis LPS stimulates the expression of LPS-binding protein in human oral keratinocytes in vitro. Innate Immunity. 19: 66-75. PMID 22736337 DOI: 10.1177/1753425912450348  0.539
2012 Hajishengallis G, Darveau RP, Curtis MA. The keystone-pathogen hypothesis. Nature Reviews. Microbiology. 10: 717-25. PMID 22941505 DOI: 10.1038/Nrmicro2873  0.373
2012 Darveau RP, Hajishengallis G, Curtis MA. Porphyromonas gingivalis as a potential community activist for disease. Journal of Dental Research. 91: 816-20. PMID 22772362 DOI: 10.1177/0022034512453589  0.429
2011 Hajishengallis G, Liang S, Payne MA, Hashim A, Jotwani R, Eskan MA, McIntosh ML, Alsam A, Kirkwood KL, Lambris JD, Darveau RP, Curtis MA. Low-abundance biofilm species orchestrates inflammatory periodontal disease through the commensal microbiota and complement. Cell Host & Microbe. 10: 497-506. PMID 22036469 DOI: 10.1016/J.Chom.2011.10.006  0.402
2011 Curtis MA, Zenobia C, Darveau RP. The relationship of the oral microbiotia to periodontal health and disease. Cell Host & Microbe. 10: 302-6. PMID 22018230 DOI: 10.1016/J.Chom.2011.09.008  0.776
2011 Herath TD, Wang Y, Seneviratne CJ, Lu Q, Darveau RP, Wang CY, Jin L. Porphyromonas gingivalis lipopolysaccharide lipid A heterogeneity differentially modulates the expression of IL-6 and IL-8 in human gingival fibroblasts. Journal of Clinical Periodontology. 38: 694-701. PMID 21752043 DOI: 10.1111/J.1600-051X.2011.01741.X  0.423
2011 Curtis MA, Percival RS, Devine D, Darveau RP, Coats SR, Rangarajan M, Tarelli E, Marsh PD. Temperature-dependent modulation of Porphyromonas gingivalis lipid A structure and interaction with the innate host defenses. Infection and Immunity. 79: 1187-93. PMID 21220483 DOI: 10.1128/Iai.00900-10  0.498
2011 Berezow AB, Darveau RP. Microbial shift and periodontitis. Periodontology 2000. 55: 36-47. PMID 21134227 DOI: 10.1111/J.1600-0757.2010.00350.X  0.784
2011 Coats SR, Berezow AB, To TT, Jain S, Bainbridge BW, Banani KP, Darveau RP. The lipid A phosphate position determines differential host Toll-like receptor 4 responses to phylogenetically related symbiotic and pathogenic bacteria. Infection and Immunity. 79: 203-10. PMID 20974832 DOI: 10.1128/Iai.00937-10  0.824
2010 Jain S, Darveau RP. Contribution of Porphyromonas gingivalis lipopolysaccharide to periodontitis. Periodontology 2000. 54: 53-70. PMID 20712633 DOI: 10.1111/J.1600-0757.2009.00333.X  0.55
2010 Zaric S, Shelburne C, Darveau R, Quinn DJ, Weldon S, Taggart CC, Coulter WA. Impaired immune tolerance to Porphyromonas gingivalis lipopolysaccharide promotes neutrophil migration and decreased apoptosis. Infection and Immunity. 78: 4151-6. PMID 20679442 DOI: 10.1128/Iai.00600-10  0.519
2010 Chang J, Jain S, Carl DJ, Paolella L, Darveau RP, Gravett MG, Adams Waldorf KM. Differential host response to LPS variants in amniochorion and the TLR4/MD-2 system in Macaca nemestrina. Placenta. 31: 811-7. PMID 20619890 DOI: 10.1016/j.placenta.2010.06.010  0.426
2010 Darveau RP. Periodontitis: a polymicrobial disruption of host homeostasis. Nature Reviews. Microbiology. 8: 481-90. PMID 20514045 DOI: 10.1038/Nrmicro2337  0.426
2009 Coats SR, To TT, Jain S, Braham PH, Darveau RP. Porphyromonas gingivalis resistance to polymyxin B is determined by the lipid A 4'-phosphatase, PGN_0524. International Journal of Oral Science. 1: 126-35. PMID 20657724 DOI: 10.4248/Ijos.09062  0.321
2009 Braham P, Herron C, Street C, Darveau R. Antimicrobial photodynamic therapy may promote periodontal healing through multiple mechanisms. Journal of Periodontology. 80: 1790-8. PMID 19905948 DOI: 10.1902/Jop.2009.090214  0.328
2009 Lu Q, Darveau RP, Samaranayake LP, Wang CY, Jin L. Differential modulation of human {beta}-defensins expression in human gingival epithelia by Porphyromonas gingivalis lipopolysaccharide with tetra- and penta-acylated lipid A structures. Innate Immunity. 15: 325-35. PMID 19675119 DOI: 10.1177/1753425909104899  0.563
2009 Coats SR, Jones JW, Do CT, Braham PH, Bainbridge BW, To TT, Goodlett DR, Ernst RK, Darveau RP. Human Toll-like receptor 4 responses to P. gingivalis are regulated by lipid A 1- and 4'-phosphatase activities. Cellular Microbiology. 11: 1587-99. PMID 19552698 DOI: 10.1111/J.1462-5822.2009.01349.X  0.835
2009 Berezow AB, Ernst RK, Coats SR, Braham PH, Karimi-Naser LM, Darveau RP. The structurally similar, penta-acylated lipopolysaccharides of Porphyromonas gingivalis and Bacteroides elicit strikingly different innate immune responses. Microbial Pathogenesis. 47: 68-77. PMID 19460428 DOI: 10.1016/J.Micpath.2009.04.015  0.833
2009 Darveau RP. The oral microbial consortium's interaction with the periodontal innate defense system. Dna and Cell Biology. 28: 389-95. PMID 19435427 DOI: 10.1089/Dna.2009.0864  0.415
2009 Horst OV, Tompkins KA, Coats SR, Braham PH, Darveau RP, Dale BA. TGF-beta1 Inhibits TLR-mediated odontoblast responses to oral bacteria. Journal of Dental Research. 88: 333-8. PMID 19407153 DOI: 10.1177/0022034509334846  0.407
2009 Darveau RP. Bacteria modulate host-cell responses by capitalizing on the lipid raft structure. Future Microbiology. 4: 155-7. PMID 19257842 DOI: 10.2217/17460913.4.2.155  0.492
2009 Chino T, Santer DM, Giordano D, Chen C, Li C, Chen CH, Darveau RP, Clark EA. Effects of oral commensal and pathogenic bacteria on human dendritic cells. Oral Microbiology and Immunology. 24: 96-103. PMID 19239635 DOI: 10.1111/J.1399-302X.2008.00478.X  0.428
2008 Brissette CA, Pham TT, Coats SR, Darveau RP, Lukehart SA. Treponema denticola does not induce production of common innate immune mediators from primary gingival epithelial cells. Oral Microbiology and Immunology. 23: 474-81. PMID 18954353 DOI: 10.1111/J.1399-302X.2008.00452.X  0.323
2008 Swoboda JR, Kiyak HA, Darveau R, Persson GR. Correlates of periodontal decline and biologic markers in older adults. Journal of Periodontology. 79: 1920-6. PMID 18834247 DOI: 10.1902/Jop.2008.080005  0.303
2008 Liu R, Desta T, Raptis M, Darveau RP, Graves DT. P. gingivalis and E. coli lipopolysaccharides exhibit different systemic but similar local induction of inflammatory markers. Journal of Periodontology. 79: 1241-7. PMID 18597607 DOI: 10.1902/Jop.2008.070575  0.448
2008 Dixon DR, Karimi-Naser L, Darveau RP, Leung KP. The anti-endotoxic effects of the KSL-W decapeptide on Escherichia coli O55:B5 and various oral lipopolysaccharides. Journal of Periodontal Research. 43: 422-30. PMID 18503516 DOI: 10.1111/J.1600-0765.2007.01067.X  0.62
2008 Bainbridge BW, Karimi-Naser L, Reife R, Blethen F, Ernst RK, Darveau RP. Acyl chain specificity of the acyltransferases LpxA and LpxD and substrate availability contribute to lipid A fatty acid heterogeneity in Porphyromonas gingivalis. Journal of Bacteriology. 190: 4549-58. PMID 18456814 DOI: 10.1128/Jb.00234-08  0.648
2008 Quinchia-Rios BH, Guerrero M, Abozeid S, Bainbridge B, Darveau R, Compton T, Bertics PJ. Down-regulation of epidermal growth factor receptor-dependent signaling by Porphyromonas gingivalis lipopolysaccharide in life-expanded human gingival fibroblasts. Journal of Periodontal Research. 43: 290-304. PMID 18221293 DOI: 10.1111/J.1600-0765.2007.01029.X  0.668
2007 Veerayutthwilai O, Byers MR, Pham TT, Darveau RP, Dale BA. Differential regulation of immune responses by odontoblasts. Oral Microbiology and Immunology. 22: 5-13. PMID 17241164 DOI: 10.1111/j.1399-302X.2007.00310.x  0.393
2007 Coats SR, Do CT, Karimi-Naser LM, Braham PH, Darveau RP. Antagonistic lipopolysaccharides block E. coli lipopolysaccharide function at human TLR4 via interaction with the human MD-2 lipopolysaccharide binding site. Cellular Microbiology. 9: 1191-202. PMID 17217428 DOI: 10.1111/J.1462-5822.2006.00859.X  0.759
2007 Chen C, Coats SR, Bumgarner RE, Darveau RP. Hierarchical gene expression profiles of HUVEC stimulated by different lipid A structures obtained from Porphyromonas gingivalis and Escherichia coli. Cellular Microbiology. 9: 1028-38. PMID 17166236 DOI: 10.1111/J.1462-5822.2006.00849.X  0.487
2006 Al-Qutub MN, Braham PH, Karimi-Naser LM, Liu X, Genco CA, Darveau RP. Hemin-dependent modulation of the lipid A structure of Porphyromonas gingivalis lipopolysaccharide. Infection and Immunity. 74: 4474-85. PMID 16861633 DOI: 10.1128/Iai.01924-05  0.799
2006 Nemoto E, Darveau RP, Foster BL, Nogueira-Filho GR, Somerman MJ. Regulation of cementoblast function by P. gingivalis lipopolysaccharide via TLR2. Journal of Dental Research. 85: 733-8. PMID 16861291 DOI: 10.1177/154405910608500809  0.374
2006 Reife RA, Coats SR, Al-Qutub M, Dixon DM, Braham PA, Billharz RJ, Howald WN, Darveau RP. Porphyromonas gingivalis lipopolysaccharide lipid A heterogeneity: differential activities of tetra- and penta-acylated lipid A structures on E-selectin expression and TLR4 recognition. Cellular Microbiology. 8: 857-68. PMID 16611234 DOI: 10.1111/J.1462-5822.2005.00672.X  0.814
2006 Bainbridge BW, Coats SR, Pham TT, Reife RA, Darveau RP. Expression of a Porphyromonas gingivalis lipid A palmitylacyltransferase in Escherichia coli yields a chimeric lipid A with altered ability to stimulate interleukin-8 secretion. Cellular Microbiology. 8: 120-9. PMID 16367871 DOI: 10.1111/J.1462-5822.2005.00605.X  0.729
2005 Ren L, Leung WK, Darveau RP, Jin L. The expression profile of lipopolysaccharide-binding protein, membrane-bound CD14, and toll-like receptors 2 and 4 in chronic periodontitis. Journal of Periodontology. 76: 1950-9. PMID 16274315 DOI: 10.1902/Jop.2005.76.11.1950  0.365
2005 Coats SR, Pham TT, Bainbridge BW, Reife RA, Darveau RP. MD-2 mediates the ability of tetra-acylated and penta-acylated lipopolysaccharides to antagonize Escherichia coli lipopolysaccharide at the TLR4 signaling complex. Journal of Immunology (Baltimore, Md. : 1950). 175: 4490-8. PMID 16177092 DOI: 10.4049/Jimmunol.175.7.4490  0.728
2005 Dixon DR, Darveau RP. Lipopolysaccharide heterogeneity: innate host responses to bacterial modification of lipid a structure. Journal of Dental Research. 84: 584-95. PMID 15972584 DOI: 10.1177/154405910508400702  0.708
2005 Tanabe H, Ayabe T, Bainbridge B, Guina T, Ernst RK, Darveau RP, Miller SI, Ouellette AJ. Mouse paneth cell secretory responses to cell surface glycolipids of virulent and attenuated pathogenic bacteria. Infection and Immunity. 73: 2312-20. PMID 15784576 DOI: 10.1128/Iai.73.4.2312-2320.2005  0.714
2004 Dixon DR, Reife RA, Cebra JJ, Darveau RP. Commensal bacteria influence innate status within gingival tissues: a pilot study. Journal of Periodontology. 75: 1486-92. PMID 15633325 DOI: 10.1902/Jop.2004.75.11.1486  0.559
2004 Darveau RP, Pham TT, Lemley K, Reife RA, Bainbridge BW, Coats SR, Howald WN, Way SS, Hajjar AM. Porphyromonas gingivalis lipopolysaccharide contains multiple lipid A species that functionally interact with both toll-like receptors 2 and 4. Infection and Immunity. 72: 5041-51. PMID 15321997 DOI: 10.1128/Iai.72.9.5041-5051.2004  0.738
2004 Nociti FH, Foster BL, Barros SP, Darveau RP, Somerman MJ. Cementoblast gene expression is regulated by Porphyromonas gingivalis lipopolysaccharide partially via toll-like receptor-4/MD-2. Journal of Dental Research. 83: 602-7. PMID 15271967 DOI: 10.1177/154405910408300804  0.372
2004 Lu Q, Jin L, Darveau RP, Samaranayake LP. Expression of human beta-defensins-1 and -2 peptides in unresolved chronic periodontitis. Journal of Periodontal Research. 39: 221-7. PMID 15206914 DOI: 10.1111/J.1600-0765.2004.00727.X  0.33
2004 Jin L, Ren L, Leung WK, Darveau RP. The in vivo expression of membrane-bound CD14 in periodontal health and disease. Journal of Periodontology. 75: 578-85. PMID 15152823 DOI: 10.1902/Jop.2004.75.4.578  0.422
2004 Dixon DR, Bainbridge BW, Darveau RP. Modulation of the innate immune response within the periodontium. Periodontology 2000. 35: 53-74. PMID 15107058 DOI: 10.1111/J.0906-6713.2004.003556.X  0.728
2003 Coats SR, Reife RA, Bainbridge BW, Pham TT, Darveau RP. Porphyromonas gingivalis lipopolysaccharide antagonizes Escherichia coli lipopolysaccharide at toll-like receptor 4 in human endothelial cells. Infection and Immunity. 71: 6799-807. PMID 14638766 DOI: 10.1128/Iai.71.12.6799-6807.2003  0.719
2002 Bainbridge BW, Coats SR, Darveau RP. Porphyromonas gingivalis lipopolysaccharide displays functionally diverse interactions with the innate host defense system. Annals of Periodontology / the American Academy of Periodontology. 7: 29-37. PMID 16013214 DOI: 10.1902/Annals.2002.7.1.29  0.776
2002 Roberts FA, Darveau RP. Beneficial bacteria of the periodontium. Periodontology 2000. 30: 40-50. PMID 12236894 DOI: 10.1034/J.1600-0757.2002.03004.X  0.366
2002 Darveau RP, Arbabi S, Garcia I, Bainbridge B, Maier RV. Porphyromonas gingivalis lipopolysaccharide is both agonist and antagonist for p38 mitogen-activated protein kinase activation. Infection and Immunity. 70: 1867-73. PMID 11895949 DOI: 10.1128/Iai.70.4.1867-1873.2002  0.733
2001 Bainbridge BW, Darveau RP. Porphyromonas gingivalis lipopolysaccharide: an unusual pattern recognition receptor ligand for the innate host defense system. Acta Odontologica Scandinavica. 59: 131-8. PMID 11501881 DOI: 10.1080/000163501750266710  0.752
2000 Krisanaprakornkit S, Kimball JR, Weinberg A, Darveau RP, Bainbridge BW, Dale BA. Inducible expression of human beta-defensin 2 by Fusobacterium nucleatum in oral epithelial cells: multiple signaling pathways and role of commensal bacteria in innate immunity and the epithelial barrier. Infection and Immunity. 68: 2907-15. PMID 10768988 DOI: 10.1128/Iai.68.5.2907-2915.2000  0.661
2000 Cunningham MD, Shapiro RA, Seachord C, Ratcliffe K, Cassiano L, Darveau RP. CD14 employs hydrophilic regions to 'capture' lipopolysaccharides Journal of Immunology. 164: 3255-3263. PMID 10706718 DOI: 10.4049/Jimmunol.164.6.3255  0.428
1999 Hedlund M, Wachtler C, Johansson E, Hang L, Somerville JE, Darveau RP, Svanborg C. P fimbriae-dependent, lipopolysaccharide-independent activation of epithelial cytokine responses Molecular Microbiology. 33: 693-703. PMID 10447879 DOI: 10.1046/j.1365-2958.1999.01513.x  0.388
1999 Cunningham MD, Bajorath J, Somerville JE, Darveau RP. Escherichia coli and Porphyromonas gingivalis lipopolysaccharide interactions with CD14: Implications for myeloid and nonmyeloid cell activation Clinical Infectious Diseases. 28: 497-504. PMID 10194067 DOI: 10.1086/515158  0.471
1998 Gu K, Bainbridge B, Darveau RP, Page RC. Antigenic components of Actinobacillus actinomycetemcomitans lipopolysaccharide recognized by sera from patients with localized juvenile periodontitis. Oral Microbiology and Immunology. 13: 150-7. PMID 10093529  0.612
1998 Darveau RP. Lipid A diversity and the innate host response to bacterial infection Current Opinion in Microbiology. 1: 36-42. PMID 10066466 DOI: 10.1016/S1369-5274(98)80140-9  0.491
1997 Bainbridge BW, Page RC, Darveau RP. Serum antibodies to Porphyromonas gingivalis block the prostaglandin E2 response to lipopolysaccharide by mononuclear cells. Infection and Immunity. 65: 4801-5. PMID 9353068 DOI: 10.1128/Iai.65.11.4801-4805.1997  0.735
1997 Ou JG, Bainbridge B, Gu K, Sims TJ, Whitney CW, Darveau RP, Chen HA, Houston LS, Page RC. Recognition of antigenic epitopes in lipopolysaccharide and protein from Actinobacillus actinomycetemcomitans by serum antibodies in untreated rapidly progressive periodontitis patients. Oral Microbiology and Immunology. 12: 11-9. PMID 9151639 DOI: 10.1111/J.1399-302X.1997.Tb00361.X  0.612
1997 Guo L, Lim KB, Gunn JS, Bainbridge B, Darveau RP, Hackett M, Miller SI. Regulation of lipid A modifications by Salmonella typhimurium virulence genes phoP-phoQ Science. 276: 250-253. PMID 9092473 DOI: 10.1126/Science.276.5310.250  0.706
1997 Shapiro RA, Cunningham MD, Ratcliffe K, Seachord C, Blake J, Bajorath J, Aruffo A, Darveau RP. Identification of CD14 residues involved in specific lipopolysaccharide recognition Infection and Immunity. 65: 293-297. PMID 8975926  0.331
1996 Vasel D, Sims TJ, Bainbridge B, Houston L, Darveau R, Page RC. Shared antigens of Porphyromonas gingivalis and Bacteroides forsythus. Oral Microbiology and Immunology. 11: 226-35. PMID 9002874 DOI: 10.1111/J.1399-302X.1996.Tb00174.X  0.658
1996 Cunningham MD, Seachord C, Ratcliffe K, Bainbridge B, Aruffo A, Darveau RP. Helicobacter pylori and Porphyromonas gingivalis lipopolysaccharides are poorly transferred to recombinant soluble CD14 Infection and Immunity. 64: 3601-3608. PMID 8751905 DOI: 10.1128/Iai.64.9.3601-3608.1996  0.651
1996 Somerville JE, Cassiano L, Bainbridge B, Cunningham MD, Darveau RP. A novel Escherichia coli lipid A mutant that produces an antiinflammatory lipopolysaccharide Journal of Clinical Investigation. 97: 359-365. PMID 8567955 DOI: 10.1172/Jci118423  0.709
1995 Reife RA, Shapiro RA, Bamber BA, Berry KK, Mick GE, Darveau RP. Porphyromonas gingivalis lipopolysaccharide is poorly recognized by molecular components of innate host defense in a mouse model of early inflammation Infection and Immunity. 63: 4686-4694. PMID 7591124  0.391
1995 Darveau RP, Cunningham MD, Bailey T, Seachord C, Ratcliffe K, Bainbridge B, Dietsch M, Page RC, Aruffo A. Ability of bacteria associated with chronic inflammatory disease to stimulate E-selectin expression and promote neutrophil adhesion Infection and Immunity. 63: 1311-1317. PMID 7534275 DOI: 10.1128/Iai.63.4.1311-1317.1995  0.691
1994 Sjöström K, Ou J, Whitney C, Johnson B, Darveau R, Engel D, Page RC. Effect of treatment on titer, function, and antigen recognition of serum antibodies to Actinobacillus actinomycetemcomitans in patients with rapidly progressive periodontitis. Infection and Immunity. 62: 145-51. PMID 8262620 DOI: 10.1128/Iai.62.1.145-151.1994  0.356
1994 Persson GR, Engel D, Whitney C, Darveau R, Weinberg A, Brunsvold M, Page RC. Immunization against Porphyromonas gingivalis inhibits progression of experimental periodontitis in nonhuman primates. Infection and Immunity. 62: 1026-31. PMID 8112836 DOI: 10.1128/Iai.62.3.1026-1031.1994  0.397
1994 Persson GR, Engel LD, Whitney CW, Weinberg A, Moncla BJ, Darveau RP, Houston L, Braham P, Page RC. Macaca fascicularis as a model in which to assess the safety and efficacy of a vaccine for periodontitis Oral Microbiology and Immunology. 9: 104-111. PMID 8008428 DOI: 10.1111/J.1399-302X.1994.Tb00043.X  0.312
1992 Page RC, Sims TJ, Moncla BJ, Darveau RP, Bainbridge B, Engel LD. Reactive antigens of the periodontopathic bacterium. Actinobacillus actinomycetemcomitans. Advances in Experimental Medicine and Biology. 327: 243-53. PMID 1295343 DOI: 10.1007/978-1-4615-3410-5_26  0.569
1991 Page RC, Sims TJ, Engel LD, Moncla BJ, Bainbridge B, Stray J, Darveau RP. The immunodominant outer membrane antigen of Actinobacillus actinomycetemcomitans is located in the serotype-specific high-molecular-mass carbohydrate moiety of lipopolysaccharide. Infection and Immunity. 59: 3451-62. PMID 1716610 DOI: 10.1128/Iai.59.10.3451-3462.1991  0.684
1991 Sims TJ, Moncla BJ, Darveau RP, Page RC. Antigens of Actinobacillus actinomycetemcomitans recognized by patients with juvenile periodontitis and periodontally normal subjects. Infection and Immunity. 59: 913-24. PMID 1705243 DOI: 10.1128/Iai.59.3.913-924.1991  0.313
1990 Darveau RP, Cunningham MD. Influence of subinhibitory concentrations of cephalosporins on the serum sensitivity of Pseudomonas aeruginosa Journal of Infectious Diseases. 162: 914-921. PMID 2119402 DOI: 10.1093/Infdis/162.4.914  0.327
1983 Darveau RP, Hancock REW. Procedure for isolation of bacterial lipopolysaccharides from both smooth and rough Pseudomonas aeruginosa and Salmonella typhimurium strains Journal of Bacteriology. 155: 831-838. PMID 6409884  0.375
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