| Year |
Citation |
Score |
| 2023 |
Xu Y, Cohen E, Johnson CN, Parent CA, Coulombe PA. Keratin 17- and PKCα-dependent transient amplification of neutrophil influx after repeated stress to the skin. Biorxiv : the Preprint Server For Biology. PMID 37873256 DOI: 10.1101/2023.10.11.561954 |
0.325 |
|
| 2022 |
Cohen E, Johnson C, Redmond CJ, Nair RR, Coulombe PA. Revisiting the significance of keratin expression in complex epithelia. Journal of Cell Science. 135. PMID 36285538 DOI: 10.1242/jcs.260594 |
0.343 |
|
| 2021 |
Nair RR, Hsu J, Jacob JT, Pineda CM, Hobbs RP, Coulombe PA. A role for keratin 17 during DNA damage response and tumor initiation. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33762306 DOI: 10.1073/pnas.2020150118 |
0.367 |
|
| 2020 |
Jacob JT, Nair RR, Poll BG, Pineda CM, Hobbs RP, Matunis MJ, Coulombe PA. Keratin 17 regulates nuclear morphology and chromatin organization. Journal of Cell Science. PMID 33008845 DOI: 10.1242/jcs.254094 |
0.408 |
|
| 2020 |
Guo Y, Redmond CJ, Leacock KA, Brovkina MV, Ji S, Jaskula-Ranga V, Coulombe PA. Keratin 14-dependent disulfides regulate epidermal homeostasis and barrier function via 14-3-3σ and YAP1. Elife. 9. PMID 32369015 DOI: 10.7554/eLife.53165 |
0.434 |
|
| 2020 |
Steen K, Chen D, Wang F, Majumdar R, Chen S, Kumar S, Lombard DB, Weigert R, Zieman AG, Parent CA, Coulombe PA. A role for keratins in supporting mitochondrial organization and function in skin keratinocytes. Molecular Biology of the Cell. mbcE19100565. PMID 32213122 DOI: 10.1091/Mbc.E19-10-0565 |
0.35 |
|
| 2020 |
Lee CH, Kim MS, Li S, Leahy DJ, Coulombe PA. Structure-Function Analyses of a Keratin Heterotypic Complex Identify Specific Keratin Regions Involved in Intermediate Filament Assembly. Structure (London, England : 1993). PMID 31995743 DOI: 10.1016/J.Str.2020.01.002 |
0.568 |
|
| 2019 |
Zieman AG, Poll BG, Ma J, Coulombe PA. Altered keratinocyte differentiation is an early driver of keratin mutation-based palmoplantar keratoderma. Human Molecular Genetics. 28: 2255-2270. PMID 31220272 DOI: 10.1093/hmg/ddz050 |
0.415 |
|
| 2018 |
Jacob JT, Coulombe PA, Kwan R, Omary MB. Types I and II Keratin Intermediate Filaments. Cold Spring Harbor Perspectives in Biology. 10. PMID 29610398 DOI: 10.1101/cshperspect.a018275 |
0.33 |
|
| 2016 |
Kerns ML, Guss L, Fahey J, Cohen B, Hakim JM, Sung S, Lu RG, Coulombe PA. Randomized, split-body, single-blinded clinical trial of topical broccoli sprout extract: Assessing the feasibility of its use in keratin-based disorders. Journal of the American Academy of Dermatology. PMID 27889290 DOI: 10.1016/j.jaad.2016.10.009 |
0.378 |
|
| 2016 |
Hobbs RP, Jacob JT, Coulombe PA. Keratins Are Going Nuclear. Developmental Cell. 38: 227-33. PMID 27505414 DOI: 10.1016/j.devcel.2016.07.022 |
0.338 |
|
| 2016 |
Kerns ML, Hakim JM, Lu RG, Guo Y, Berroth A, Kaspar RL, Coulombe PA. Oxidative stress and dysfunctional NRF2 underlie pachyonychia congenita phenotypes. The Journal of Clinical Investigation. PMID 27183391 DOI: 10.1172/Jci84870 |
0.321 |
|
| 2016 |
Wang F, Zieman A, Coulombe PA. Skin Keratins. Methods in Enzymology. 568: 303-50. PMID 26795476 DOI: 10.1016/bs.mie.2015.09.032 |
0.41 |
|
| 2015 |
Hobbs RP, DePianto DJ, Jacob JT, Han MC, Chung BM, Batazzi AS, Poll BG, Guo Y, Han J, Ong S, Zheng W, Taube JM, ?iháková D, Wan F, Coulombe PA. Keratin-dependent regulation of Aire and gene expression in skin tumor keratinocytes. Nature Genetics. PMID 26168014 DOI: 10.1038/Ng.3355 |
0.41 |
|
| 2015 |
Chung BM, Arutyunov A, Ilagan E, Yao N, Wills-Karp M, Coulombe PA. Regulation of C-X-C chemokine gene expression by keratin 17 and hnRNP K in skin tumor keratinocytes. The Journal of Cell Biology. 208: 613-27. PMID 25713416 DOI: 10.1083/Jcb.201408026 |
0.399 |
|
| 2014 |
Alvarado DM, Coulombe PA. Directed expression of a chimeric type II keratin partially rescues keratin 5-null mice. The Journal of Biological Chemistry. 289: 19435-47. PMID 24867950 DOI: 10.1074/jbc.M114.553867 |
0.461 |
|
| 2013 |
Lessard JC, Piña-Paz S, Rotty JD, Hickerson RP, Kaspar RL, Balmain A, Coulombe PA. Keratin 16 regulates innate immunity in response to epidermal barrier breach Proceedings of the National Academy of Sciences of the United States of America. 110: 19537-19542. PMID 24218583 DOI: 10.1073/Pnas.1309576110 |
0.789 |
|
| 2013 |
Chung BM, Rotty JD, Coulombe PA. Networking galore: intermediate filaments and cell migration. Current Opinion in Cell Biology. 25: 600-12. PMID 23886476 DOI: 10.1016/J.Ceb.2013.06.008 |
0.751 |
|
| 2013 |
Pan X, Hobbs RP, Coulombe PA. The expanding significance of keratin intermediate filaments in normal and diseased epithelia. Current Opinion in Cell Biology. 25: 47-56. PMID 23270662 DOI: 10.1016/J.Ceb.2012.10.018 |
0.795 |
|
| 2013 |
Feng X, Zhang H, Margolick JB, Coulombe PA. Keratin intracellular concentration revisited: implications for keratin function in surface epithelia. The Journal of Investigative Dermatology. 133: 850-3. PMID 23190880 DOI: 10.1038/Jid.2012.397 |
0.368 |
|
| 2012 |
Hobbs RP, Lessard JC, Coulombe PA. Keratin intermediate filament proteins - novel regulators of inflammation and immunity in skin. Journal of Cell Science. 125: 5257-8. PMID 23377656 DOI: 10.1242/Jcs.122929 |
0.783 |
|
| 2012 |
Kim JS, Lee CH, Su BY, Coulombe PA. Mathematical modeling of the impact of actin and keratin filaments on keratinocyte cell spreading. Biophysical Journal. 103: 1828-38. PMID 23199911 DOI: 10.1016/J.Bpj.2012.09.016 |
0.521 |
|
| 2012 |
Lee CH, Kim MS, Chung BM, Leahy DJ, Coulombe PA. Structural basis for heteromeric assembly and perinuclear organization of keratin filaments. Nature Structural & Molecular Biology. 19: 707-15. PMID 22705788 DOI: 10.1038/Nsmb.2330 |
0.58 |
|
| 2012 |
Rotty JD, Coulombe PA. A wound-induced keratin inhibits Src activity during keratinocyte migration and tissue repair. The Journal of Cell Biology. 197: 381-9. PMID 22529101 DOI: 10.1083/Jcb.201107078 |
0.777 |
|
| 2012 |
Lessard JC, Coulombe PA. Keratin 16-null mice develop palmoplantar keratoderma, a hallmark feature of pachyonychia congenita and related disorders. The Journal of Investigative Dermatology. 132: 1384-91. PMID 22336941 DOI: 10.1038/Jid.2012.6 |
0.782 |
|
| 2012 |
Coulombe PA, Lee CH. Defining keratin protein function in skin epithelia: epidermolysis bullosa simplex and its aftermath. The Journal of Investigative Dermatology. 132: 763-75. PMID 22277943 DOI: 10.1038/jid.2011.450 |
0.638 |
|
| 2012 |
Chung BM, Murray CI, Van Eyk JE, Coulombe PA. Identification of novel interaction between annexin A2 and keratin 17: evidence for reciprocal regulation. The Journal of Biological Chemistry. 287: 7573-81. PMID 22235123 DOI: 10.1074/Jbc.M111.301549 |
0.383 |
|
| 2011 |
Pan X, Kane LA, Van Eyk JE, Coulombe PA. Type I keratin 17 protein is phosphorylated on serine 44 by p90 ribosomal protein S6 kinase 1 (RSK1) in a growth- and stress-dependent fashion. The Journal of Biological Chemistry. 286: 42403-13. PMID 22006917 DOI: 10.1074/Jbc.M111.302042 |
0.818 |
|
| 2010 |
Kim JS, Lee CH, Coulombe PA. Modeling the self-organization property of keratin intermediate filaments. Biophysical Journal. 99: 2748-56. PMID 21044571 DOI: 10.1016/J.Bpj.2010.09.023 |
0.561 |
|
| 2010 |
Kerns M, DePianto D, Yamamoto M, Coulombe PA. Differential modulation of keratin expression by sulforaphane occurs via Nrf2-dependent and -independent pathways in skin epithelia. Molecular Biology of the Cell. 21: 4068-75. PMID 20926689 DOI: 10.1091/Mbc.E10-02-0153 |
0.388 |
|
| 2010 |
Depianto D, Kerns ML, Dlugosz AA, Coulombe PA. Keratin 17 promotes epithelial proliferation and tumor growth by polarizing the immune response in skin. Nature Genetics. 42: 910-4. PMID 20871598 DOI: 10.1038/Ng.665 |
0.313 |
|
| 2010 |
Rotty JD, Hart GW, Coulombe PA. Stressing the role of O-GlcNAc: linking cell survival to keratin modification. Nature Cell Biology. 12: 847-9. PMID 20811358 DOI: 10.1038/Ncb0910-847 |
0.693 |
|
| 2009 |
Lee CH, Coulombe PA. Self-organization of keratin intermediate filaments into cross-linked networks. The Journal of Cell Biology. 186: 409-21. PMID 19651890 DOI: 10.1083/jcb.200810196 |
0.571 |
|
| 2009 |
Coulombe PA, Kerns ML, Fuchs E. Epidermolysis bullosa simplex: a paradigm for disorders of tissue fragility. The Journal of Clinical Investigation. 119: 1784-93. PMID 19587453 DOI: 10.1172/Jci38177 |
0.386 |
|
| 2008 |
Gu LH, Coulombe PA. Hedgehog signaling, keratin 6 induction, and sebaceous gland morphogenesis: implications for pachyonychia congenita and related conditions. The American Journal of Pathology. 173: 752-61. PMID 18688029 DOI: 10.2353/Ajpath.2008.071089 |
0.522 |
|
| 2008 |
Larouche D, Tong X, Fradette J, Coulombe PA, Germain L. Vibrissa hair bulge houses two populations of skin epithelial stem cells distinct by their keratin profile. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 1404-15. PMID 18162489 DOI: 10.1096/Fj.07-8109Com |
0.733 |
|
| 2007 |
Kim S, Kellner J, Lee CH, Coulombe PA. Interaction between the keratin cytoskeleton and eEF1Bgamma affects protein synthesis in epithelial cells. Nature Structural & Molecular Biology. 14: 982-3. PMID 17906640 DOI: 10.1038/Nsmb1301 |
0.528 |
|
| 2007 |
Kerns ML, DePianto D, Dinkova-Kostova AT, Talalay P, Coulombe PA. Reprogramming of keratin biosynthesis by sulforaphane restores skin integrity in epidermolysis bullosa simplex Proceedings of the National Academy of Sciences of the United States of America. 104: 14460-14465. PMID 17724334 DOI: 10.1073/pnas.0706486104 |
0.4 |
|
| 2007 |
Kim S, Coulombe PA. Intermediate filament scaffolds fulfill mechanical, organizational, and signaling functions in the cytoplasm. Genes & Development. 21: 1581-97. PMID 17606637 DOI: 10.1101/Gad.1552107 |
0.406 |
|
| 2007 |
Gu LH, Coulombe PA. Keratin function in skin epithelia: a broadening palette with surprising shades. Current Opinion in Cell Biology. 19: 13-23. PMID 17178453 DOI: 10.1016/J.Ceb.2006.12.007 |
0.478 |
|
| 2007 |
Gu LH, Coulombe PA. Keratin expression provides novel insight into the morphogenesis and function of the companion layer in hair follicles. The Journal of Investigative Dermatology. 127: 1061-73. PMID 17170733 DOI: 10.1038/Sj.Jid.5700673 |
0.416 |
|
| 2006 |
Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW. New consensus nomenclature for mammalian keratins. The Journal of Cell Biology. 174: 169-74. PMID 16831889 DOI: 10.1083/Jcb.200603161 |
0.375 |
|
| 2006 |
Kim S, Wong P, Coulombe PA. A keratin cytoskeletal protein regulates protein synthesis and epithelial cell growth. Nature. 441: 362-5. PMID 16710422 DOI: 10.1038/Nature04659 |
0.392 |
|
| 2006 |
Tong X, Coulombe PA. Keratin 17 modulates hair follicle cycling in a TNFalpha-dependent fashion. Genes & Development. 20: 1353-64. PMID 16702408 DOI: 10.1101/gad.1387406 |
0.731 |
|
| 2005 |
Bianchi N, Depianto D, McGowan K, Gu C, Coulombe PA. Exploiting the keratin 17 gene promoter to visualize live cells in epithelial appendages of mice. Molecular and Cellular Biology. 25: 7249-59. PMID 16055733 DOI: 10.1128/Mcb.25.16.7249-7259.2005 |
0.783 |
|
| 2005 |
Bernot KM, Lee CH, Coulombe PA. A small surface hydrophobic stripe in the coiled-coil domain of type I keratins mediates tetramer stability. The Journal of Cell Biology. 168: 965-74. PMID 15767464 DOI: 10.1083/Jcb.200408116 |
0.786 |
|
| 2005 |
Gu LH, Coulombe PA. Defining the properties of the nonhelical tail domain in type II keratin 5: insight from a bullous disease-causing mutation. Molecular Biology of the Cell. 16: 1427-38. PMID 15647384 DOI: 10.1091/Mbc.E04-06-0498 |
0.455 |
|
| 2005 |
Wong P, Domergue R, Coulombe PA. Overcoming functional redundancy to elicit pachyonychia congenita-like nail lesions in transgenic mice. Molecular and Cellular Biology. 25: 197-205. PMID 15601842 DOI: 10.1128/Mcb.25.1.197-205.2005 |
0.51 |
|
| 2004 |
Coulombe PA, Tong X, Mazzalupo S, Wang Z, Wong P. Great promises yet to be fulfilled: defining keratin intermediate filament function in vivo. European Journal of Cell Biology. 83: 735-46. PMID 15679118 DOI: 10.1078/0171-9335-00443 |
0.834 |
|
| 2004 |
Bernot KM, Coulombe PA, Wong P. Skin: an ideal model system to study keratin genes and proteins. Methods in Cell Biology. 78: 453-87. PMID 15646628 DOI: 10.1016/S0091-679X(04)78016-4 |
0.791 |
|
| 2004 |
Callahan CA, Ofstad T, Horng L, Wang JK, Zhen HH, Coulombe PA, Oro AE. MIM/BEG4, a Sonic hedgehog-responsive gene that potentiates Gli-dependent transcription Genes and Development. 18: 2724-2729. PMID 15545630 DOI: 10.1101/Gad.1221804 |
0.38 |
|
| 2004 |
Omary MB, Coulombe PA, McLean WH. Intermediate filament proteins and their associated diseases. The New England Journal of Medicine. 351: 2087-100. PMID 15537907 DOI: 10.1056/Nejmra040319 |
0.407 |
|
| 2004 |
DePianto D, Coulombe PA. Intermediate filaments and tissue repair. Experimental Cell Research. 301: 68-76. PMID 15501447 DOI: 10.1016/J.Yexcr.2004.08.007 |
0.407 |
|
| 2004 |
Presland RB, Coulombe PA, Eckert RL, Mao-Qiang M, Feingold KR, Elias PM. Barrier function in transgenic mice overexpressing K16, involucrin, and filaggrin in the suprabasal epidermis. The Journal of Investigative Dermatology. 123: 603-6. PMID 15304104 DOI: 10.1111/J.0022-202X.2004.23226.X |
0.393 |
|
| 2004 |
Coulombe PA, Wong P. Cytoplasmic intermediate filaments revealed as dynamic and multipurpose scaffolds. Nature Cell Biology. 6: 699-706. PMID 15303099 DOI: 10.1038/Ncb0804-699 |
0.388 |
|
| 2004 |
Zarach JM, Beaudoin GM, Coulombe PA, Thompson CC. The co-repressor hairless has a role in epithelial cell differentiation in the skin. Development (Cambridge, England). 131: 4189-200. PMID 15280217 DOI: 10.1242/dev.01303 |
0.408 |
|
| 2004 |
Tong X, Coulombe PA. A novel mouse type I intermediate filament gene, keratin 17n (K17n), exhibits preferred expression in nail tissue. The Journal of Investigative Dermatology. 122: 965-70. PMID 15102087 DOI: 10.1111/J.0022-202X.2004.22422.X |
0.735 |
|
| 2003 |
Wang Z, Wong P, Langbein L, Schweizer J, Coulombe PA. Type II epithelial keratin 6hf (K6hf) is expressed in the companion layer, matrix, and medulla in anagen-stage hair follicles. The Journal of Investigative Dermatology. 121: 1276-82. PMID 14675170 DOI: 10.1111/J.1523-1747.2003.12644.X |
0.438 |
|
| 2003 |
Wong P, Coulombe PA. Loss of keratin 6 (K6) proteins reveals a function for intermediate filaments during wound repair. The Journal of Cell Biology. 163: 327-37. PMID 14568992 DOI: 10.1083/Jcb.200305032 |
0.503 |
|
| 2003 |
Yamada S, Wirtz D, Coulombe PA. The mechanical properties of simple epithelial keratins 8 and 18: discriminating between interfacial and bulk elasticities. Journal of Structural Biology. 143: 45-55. PMID 12892725 DOI: 10.1016/S1047-8477(03)00101-1 |
0.433 |
|
| 2003 |
Coulombe PA. Wound epithelialization: accelerating the pace of discovery. The Journal of Investigative Dermatology. 121: 219-30. PMID 12880412 DOI: 10.1046/J.1523-1747.2003.12387.X |
0.341 |
|
| 2003 |
Tong X, Coulombe PA. Mouse models of alopecia: identifying structural genes that are baldly needed. Trends in Molecular Medicine. 9: 79-84. PMID 12615042 DOI: 10.1016/S1471-4914(02)00025-4 |
0.708 |
|
| 2003 |
Mazzalupo S, Wong P, Martin P, Coulombe PA. Role for keratins 6 and 17 during wound closure in embryonic mouse skin. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 226: 356-65. PMID 12557214 DOI: 10.1002/Dvdy.10245 |
0.821 |
|
| 2002 |
Bernot KM, Coulombe PA, McGowan KM. Keratin 16 expression defines a subset of epithelial cells during skin morphogenesis and the hair cycle. The Journal of Investigative Dermatology. 119: 1137-49. PMID 12445204 DOI: 10.1046/J.1523-1747.2002.19518.X |
0.787 |
|
| 2002 |
Coulombe PA. A new fold on an old story: attachment of intermediate filaments to desmosomes. Nature Structural Biology. 9: 560-2. PMID 12145641 DOI: 10.1038/Nsb0802-560 |
0.309 |
|
| 2002 |
McGowan KM, Tong X, Colucci-Guyon E, Langa F, Babinet C, Coulombe PA. Keratin 17 null mice exhibit age- and strain-dependent alopecia. Genes & Development. 16: 1412-22. PMID 12050118 DOI: 10.1101/Gad.979502 |
0.735 |
|
| 2002 |
Mazzalupo S, Wawersik MJ, Coulombe PA. An ex vivo assay to assess the potential of skin keratinocytes for wound epithelialization. The Journal of Investigative Dermatology. 118: 866-70. PMID 11982766 DOI: 10.1046/J.1523-1747.2002.01736.X |
0.786 |
|
| 2002 |
Yamada S, Wirtz D, Coulombe PA. Pairwise assembly determines the intrinsic potential for self-organization and mechanical properties of keratin filaments. Molecular Biology of the Cell. 13: 382-91. PMID 11809846 DOI: 10.1091/Mbc.01-10-0522 |
0.469 |
|
| 2002 |
Coulombe PA, Omary MB. 'Hard' and 'soft' principles defining the structure, function and regulation of keratin intermediate filaments. Current Opinion in Cell Biology. 14: 110-22. PMID 11792552 DOI: 10.1016/S0955-0674(01)00301-5 |
0.478 |
|
| 2001 |
Coulombe PA, Ma L, Yamada S, Wawersik M. Intermediate filaments at a glance. Journal of Cell Science. 114: 4345-7. PMID 11792800 |
0.642 |
|
| 2001 |
Bousquet O, Ma L, Yamada S, Gu C, Idei T, Takahashi K, Wirtz D, Coulombe PA. The nonhelical tail domain of keratin 14 promotes filament bundling and enhances the mechanical properties of keratin intermediate filaments in vitro. The Journal of Cell Biology. 155: 747-54. PMID 11724817 DOI: 10.1083/Jcb.200104063 |
0.732 |
|
| 2001 |
Wawersik MJ, Mazzalupo S, Nguyen D, Coulombe PA. Increased levels of keratin 16 alter epithelialization potential of mouse skin keratinocytes in vivo and ex vivo. Molecular Biology of the Cell. 12: 3439-50. PMID 11694579 DOI: 10.1091/Mbc.12.11.3439 |
0.82 |
|
| 2001 |
Ma L, Yamada S, Wirtz D, Coulombe PA. A 'hot-spot' mutation alters the mechanical properties of keratin filament networks. Nature Cell Biology. 3: 503-6. PMID 11331879 DOI: 10.1038/35074576 |
0.743 |
|
| 2001 |
Mazzalupo S, Coulombe PA. A reporter transgene based on a human keratin 6 gene promoter is specifically expressed in the periderm of mouse embryos. Mechanisms of Development. 100: 65-9. PMID 11118885 DOI: 10.1016/S0925-4773(00)00489-5 |
0.78 |
|
| 2000 |
Wawersik M, Coulombe PA. Forced expression of keratin 16 alters the adhesion, differentiation, and migration of mouse skin keratinocytes. Molecular Biology of the Cell. 11: 3315-27. PMID 11029038 DOI: 10.1091/Mbc.11.10.3315 |
0.816 |
|
| 2000 |
Coulombe PA, Bousquet O, Ma L, Yamada S, Wirtz D. The 'ins' and 'outs' of intermediate filament organization. Trends in Cell Biology. 10: 420-8. PMID 10998598 DOI: 10.1016/S0962-8924(00)01828-6 |
0.706 |
|
| 2000 |
Wong P, Colucci-Guyon E, Takahashi K, Gu C, Babinet C, Coulombe PA. Introducing a null mutation in the mouse K6alpha and K6beta genes reveals their essential structural role in the oral mucosa. The Journal of Cell Biology. 150: 921-8. PMID 10953016 DOI: 10.1083/Jcb.150.4.921 |
0.498 |
|
| 2000 |
McGowan KM, Coulombe PA. Keratin 17 expression in the hard epithelial context of the hair and nail, and its relevance for the pachyonychia congenita phenotype. The Journal of Investigative Dermatology. 114: 1101-7. PMID 10844551 DOI: 10.1046/J.1523-1747.2000.00986.X |
0.517 |
|
| 1999 |
Takahashi K, Coulombe PA, Miyachi Y. Using transgenic models to study the pathogenesis of keratin-based inherited skin diseases. Journal of Dermatological Science. 21: 73-95. PMID 10511477 DOI: 10.1016/S0923-1811(99)00023-7 |
0.46 |
|
| 1999 |
Paladini RD, Coulombe PA. The functional diversity of epidermal keratins revealed by the partial rescue of the keratin 14 null phenotype by keratin 16. The Journal of Cell Biology. 146: 1185-201. PMID 10477769 DOI: 10.1083/Jcb.146.5.1185 |
0.486 |
|
| 1999 |
Ma L, Xu J, Coulombe PA, Wirtz D. Keratin filament suspensions show unique micromechanical properties. The Journal of Biological Chemistry. 274: 19145-51. PMID 10383419 DOI: 10.1074/Jbc.274.27.19145 |
0.694 |
|
| 1999 |
Fradette J, Germain L, Seshaiah P, Coulombe PA. The type I keratin 19 possesses distinct and context-dependent assembly properties. The Journal of Biological Chemistry. 273: 35176-84. PMID 9857055 DOI: 10.1074/Jbc.273.52.35176 |
0.49 |
|
| 1998 |
Takahashi K, Yan B, Yamanishi K, Imamura S, Coulombe PA. The two functional keratin 6 genes of mouse are differentially regulated and evolved independently from their human orthologs. Genomics. 53: 170-83. PMID 9790766 DOI: 10.1006/Geno.1998.5476 |
0.488 |
|
| 1998 |
Hutton E, Paladini RD, Yu QC, Yen M, Coulombe PA, Fuchs E. Functional differences between keratins of stratified and simple epithelia. The Journal of Cell Biology. 143: 487-99. PMID 9786957 DOI: 10.1083/Jcb.143.2.487 |
0.451 |
|
| 1998 |
McGowan KM, Coulombe PA. Onset of keratin 17 expression coincides with the definition of major epithelial lineages during skin development. The Journal of Cell Biology. 143: 469-86. PMID 9786956 DOI: 10.1083/Jcb.143.2.469 |
0.556 |
|
| 1998 |
Muñoz-Mármol AM, Strasser G, Isamat M, Coulombe PA, Yang Y, Roca X, Vela E, Mate JL, Coll J, Fernández-Figueras MT, Navas-Palacios JJ, Ariza A, Fuchs E. A dysfunctional desmin mutation in a patient with severe generalized myopathy. Proceedings of the National Academy of Sciences of the United States of America. 95: 11312-7. PMID 9736733 DOI: 10.1073/Pnas.95.19.11312 |
0.343 |
|
| 1998 |
Paladini RD, Coulombe PA. Directed expression of keratin 16 to the progenitor basal cells of transgenic mouse skin delays skin maturation. The Journal of Cell Biology. 142: 1035-51. PMID 9722615 DOI: 10.1083/Jcb.142.4.1035 |
0.571 |
|
| 1998 |
Coulombe PA, Wawersik M, Paladini RD, Noensie E. Type I keratin 16 forms relatively unstable tetrameric assembly subunits with various type II keratin partners: biochemical basis and functional implications. The Biological Bulletin. 194: 364-5; discussion 36. PMID 9664664 DOI: 10.2307/1543114 |
0.815 |
|
| 1998 |
Miller SJ, Burke EM, Rader MD, Coulombe PA, Lavker RM. Re-epithelialization of porcine skin by the sweat apparatus. The Journal of Investigative Dermatology. 110: 13-9. PMID 9424080 DOI: 10.1046/j.1523-1747.1998.00087.x |
0.315 |
|
| 1998 |
Wawersik M, Paladini RD, Noensie E, Coulombe PA. A proline residue in the alpha-helical rod domain of type I keratin 16 destabilizes keratin heterotetramers. The Journal of Biological Chemistry. 272: 32557-65. PMID 9405470 DOI: 10.1074/Jbc.272.51.32557 |
0.797 |
|
| 1998 |
Takahashi K, Yan B, Yamanishi K, Imamura S, Coulombe PA. The characterization of mouse keratin 6 (K6) isoform genes suggests a distinct evolutionary origin for mouse and human K6 genes involving independent gene duplication events Journal of Dermatological Science. 16: S68. DOI: 10.1016/S0923-1811(98)83406-3 |
0.317 |
|
| 1997 |
Coulombe PA. Towards a molecular definition of keratinocyte activation after acute injury to stratified epithelia. Biochemical and Biophysical Research Communications. 236: 231-8. PMID 9240415 DOI: 10.1006/Bbrc.1997.6945 |
0.439 |
|
| 1997 |
Takahashi K, Coulombe PA. Defining a region of the human keratin 6a gene that confers inducible expression in stratified epithelia of transgenic mice. The Journal of Biological Chemistry. 272: 11979-85. PMID 9115262 DOI: 10.1074/Jbc.272.18.11979 |
0.504 |
|
| 1997 |
Bousquet O, Coulombe PA. Cytoskeleton: missing links found? Current Biology : Cb. 6: 1563-6. PMID 8994813 DOI: 10.1016/S0960-9822(02)70772-0 |
0.356 |
|
| 1997 |
Takahashi K, Coulombe PA. A transgenic mouse model with an inducible skin blistering disease phenotype. Proceedings of the National Academy of Sciences of the United States of America. 93: 14776-81. PMID 8962131 DOI: 10.1073/pnas.93.25.14776 |
0.344 |
|
| 1996 |
Uttam J, Hutton E, Coulombe PA, Anton-Lamprecht I, Yu QC, Gedde-Dahl T, Fine JD, Fuchs E. The genetic basis of epidermolysis bullosa simplex with mottled pigmentation. Proceedings of the National Academy of Sciences of the United States of America. 93: 9079-84. PMID 8799157 DOI: 10.1073/Pnas.93.17.9079 |
0.46 |
|
| 1996 |
Coulombe PA, Bravo NS, Paladini RD, Nguyen D, Takahashi K. Overexpression of human keratin 16 produces a distinct skin phenotype in transgenic mouse skin. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 73: 611-8. PMID 8714680 DOI: 10.1139/O95-067 |
0.546 |
|
| 1996 |
Paladini RD, Takahashi K, Bravo NS, Coulombe PA. Onset of re-epithelialization after skin injury correlates with a reorganization of keratin filaments in wound edge keratinocytes: defining a potential role for keratin 16. The Journal of Cell Biology. 132: 381-97. PMID 8636216 DOI: 10.1083/Jcb.132.3.381 |
0.511 |
|
| 1995 |
Takahashi K, Paladini RD, Coulombe PA. Cloning and characterization of multiple human genes and cDNAs encoding highly related type II keratin 6 isoforms. The Journal of Biological Chemistry. 270: 18581-92. PMID 7543104 DOI: 10.1074/Jbc.270.31.18581 |
0.509 |
|
| 1995 |
Paladini RD, Takahashi K, Gant TM, Coulombe PA. cDNA cloning and bacterial expression of the human type I keratin 16. Biochemical and Biophysical Research Communications. 215: 517-23. PMID 7487986 DOI: 10.1006/bbrc.1995.2495 |
0.374 |
|
| 1994 |
Takahashi K, Folmer J, Coulombe PA. Increased expression of keratin 16 causes anomalies in cytoarchitecture and keratinization in transgenic mouse skin. The Journal of Cell Biology. 127: 505-20. PMID 7523421 DOI: 10.1083/Jcb.127.2.505 |
0.562 |
|
| 1993 |
Letai A, Coulombe PA, McCormick MB, Yu QC, Hutton E, Fuchs E. Disease severity correlates with position of keratin point mutations in patients with epidermolysis bullosa simplex. Proceedings of the National Academy of Sciences of the United States of America. 90: 3197-201. PMID 7682695 DOI: 10.1073/Pnas.90.8.3197 |
0.351 |
|
| 1993 |
Coulombe PA. The cellular and molecular biology of keratins: beginning a new era. Current Opinion in Cell Biology. 5: 17-29. PMID 7680567 DOI: 10.1016/S0955-0674(05)80004-3 |
0.362 |
|
| 1992 |
Wilson AK, Coulombe PA, Fuchs E. The roles of K5 and K14 head, tail, and R/K L L E G E domains in keratin filament assembly in vitro. The Journal of Cell Biology. 119: 401-14. PMID 1383231 DOI: 10.1083/Jcb.119.2.401 |
0.387 |
|
| 1992 |
Fuchs E, Esteves RA, Coulombe PA. Transgenic mice expressing a mutant keratin 10 gene reveal the likely genetic basis for epidermolytic hyperkeratosis. Proceedings of the National Academy of Sciences of the United States of America. 89: 6906-10. PMID 1379726 DOI: 10.1073/Pnas.89.15.6906 |
0.502 |
|
| 1992 |
Fuchs E, Coulombe PA. Of mice and men: genetic skin diseases of keratin. Cell. 69: 899-902. PMID 1376637 DOI: 10.1016/0092-8674(92)90607-E |
0.501 |
|
| 1992 |
Letai A, Coulombe PA, Fuchs E. Do the ends justify the mean? Proline mutations at the ends of the keratin coiled-coil rod segment are more disruptive than internal mutations. The Journal of Cell Biology. 116: 1181-95. PMID 1371287 DOI: 10.1083/Jcb.116.5.1181 |
0.354 |
|
| 1991 |
Coulombe PA, Hutton ME, Vassar R, Fuchs E. A function for keratins and a common thread among different types of epidermolysis bullosa simplex diseases. The Journal of Cell Biology. 115: 1661-74. PMID 1721910 DOI: 10.1083/Jcb.115.6.1661 |
0.489 |
|
| 1991 |
Coulombe PA, Hutton ME, Letai A, Hebert A, Paller AS, Fuchs E. Point mutations in human keratin 14 genes of epidermolysis bullosa simplex patients: genetic and functional analyses. Cell. 66: 1301-11. PMID 1717157 DOI: 10.1016/0092-8674(91)90051-Y |
0.46 |
|
| 1991 |
McCormick MB, Coulombe PA, Fuchs E. Sorting out IF networks: consequences of domain swapping on IF recognition and assembly. The Journal of Cell Biology. 113: 1111-24. PMID 1710225 DOI: 10.1083/Jcb.113.5.1111 |
0.347 |
|
| 1991 |
Vassar R, Coulombe PA, Degenstein L, Albers K, Fuchs E. Mutant keratin expression in transgenic mice causes marked abnormalities resembling a human genetic skin disease. Cell. 64: 365-80. PMID 1703046 DOI: 10.1016/0092-8674(91)90645-F |
0.452 |
|
| 1990 |
Coulombe PA, Chan YM, Albers K, Fuchs E. Deletions in epidermal keratins leading to alterations in filament organization in vivo and in intermediate filament assembly in vitro Journal of Cell Biology. 111: 3049-3064. PMID 1702787 DOI: 10.1083/Jcb.111.6.3049 |
0.417 |
|
| 1990 |
Coulombe PA, Fuchs E. Elucidating the early stages of keratin filament assembly. The Journal of Cell Biology. 111: 153-69. PMID 1694855 DOI: 10.1083/Jcb.111.1.153 |
0.424 |
|
| 1989 |
Coulombe PA, Kopan R, Fuchs E. Expression of keratin K14 in the epidermis and hair follicle: insights into complex programs of differentiation. The Journal of Cell Biology. 109: 2295-312. PMID 2478566 DOI: 10.1083/Jcb.109.5.2295 |
0.513 |
|
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