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Lev Becker, Ph.D. - Publications

Affiliations: 
2003 Queen's University, Canada, Kingston, Ontario, Canada 
Area:
Biochemistry
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26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Kahn JH, Goddi A, Sharma A, Heiman J, Carmona A, Li Y, Hoffman A, Schoenfelt K, Ye H, Bobe AM, Becker L, Hollenberg AN, Cohen RN. SMRT Regulates Metabolic Homeostasis and Adipose Tissue Macrophage Phenotypes in Tandem. Endocrinology. PMID 32770234 DOI: 10.1210/Endocr/Bqaa132  0.303
2019 Tiwari P, Blank A, Cui C, Schoenfelt KQ, Zhou G, Xu Y, Khramtsova G, Olopade F, Shah AM, Khan SA, Rosner MR, Becker L. Metabolically activated adipose tissue macrophages link obesity to triple-negative breast cancer. The Journal of Experimental Medicine. PMID 31053611 DOI: 10.1084/Jem.20181616  0.305
2018 Reardon CA, Lingaraju A, Schoenfelt KQ, Zhou G, Cui C, Jacobs-El H, Babenko I, Hoofnagle A, Czyz D, Shuman H, Vaisar T, Becker L. Obesity and Insulin Resistance Promote Atherosclerosis through an IFNγ-Regulated Macrophage Protein Network. Cell Reports. 23: 3021-3030. PMID 29874587 DOI: 10.1016/J.Celrep.2018.05.010  0.323
2017 Coats BR, Schoenfelt KQ, Barbosa-Lorenzi VC, Peris E, Cui C, Hoffman A, Zhou G, Fernandez S, Zhai L, Hall BA, Haka AS, Shah AM, Reardon CA, Brady MJ, Rhodes CJ, ... ... Becker L, et al. Metabolically Activated Adipose Tissue Macrophages Perform Detrimental and Beneficial Functions during Diet-Induced Obesity. Cell Reports. 20: 3149-3161. PMID 28954231 DOI: 10.1016/J.Celrep.2017.08.096  0.322
2017 Tiwari P, Schoenfelt K, Blank A, Cui C, Rosner MR, Becker L. Abstract 4229: Metabolically active macrophages: A novel link between obesity and TNBC Cancer Research. 77: 4229-4229. DOI: 10.1158/1538-7445.Am2017-4229  0.324
2016 Krishnan V, Mitchell K, Miska J, George S, Shaw P, Seewaldt V, Lesniak M, Chekmareva M, Becker L, Parkash V, Miranti C, Rinker-Schaeffer C. Abstract A82: Ovarian cancer cells hijack immune functions of omental milky spots for metastatic colonization. Clinical Cancer Research. 22. DOI: 10.1158/1557-3265.Ovca15-A82  0.304
2015 Pamir N, Liu NC, Irwin A, Becker L, Peng Y, Ronsein GE, Bornfeldt KE, Duffield JS, Heinecke JW. Granulocyte/Macrophage Colony-stimulating Factor-dependent Dendritic Cells Restrain Lean Adipose Tissue Expansion. The Journal of Biological Chemistry. 290: 14656-67. PMID 25931125 DOI: 10.1074/Jbc.M115.645820  0.31
2015 Tiwari P, Schoenfelt K, Kulkarni S, Rosner M, Becker L. Abstract 2888: Metabolically activated macrophages in obesity associated TNBC Cancer Research. 75: 2888-2888. DOI: 10.1158/1538-7445.Am2015-2888  0.308
2014 Kratz M, Coats BR, Hisert KB, Hagman D, Mutskov V, Peris E, Schoenfelt KQ, Kuzma JN, Larson I, Billing PS, Landerholm RW, Crouthamel M, Gozal D, Hwang S, Singh PK, ... Becker L, et al. Metabolic dysfunction drives a mechanistically distinct proinflammatory phenotype in adipose tissue macrophages. Cell Metabolism. 20: 614-25. PMID 25242226 DOI: 10.1016/J.Cmet.2014.08.010  0.32
2012 Suzuki M, Becker L, Pritchard DK, Gharib SA, Wijsman EM, Bammler TK, Beyer RP, Vaisar T, Oram JF, Heinecke JW. Cholesterol accumulation regulates expression of macrophage proteins implicated in proteolysis and complement activation. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 2910-8. PMID 23042816 DOI: 10.1161/Atvbaha.112.300383  0.402
2012 Becker L, Liu NC, Averill MM, Yuan W, Pamir N, Peng Y, Irwin AD, Fu X, Bornfeldt KE, Heinecke JW. Unique proteomic signatures distinguish macrophages and dendritic cells. Plos One. 7: e33297. PMID 22428014 DOI: 10.1371/Journal.Pone.0033297  0.323
2011 Averill MM, Barnhart S, Becker L, Li X, Heinecke JW, Leboeuf RC, Hamerman JA, Sorg C, Kerkhoff C, Bornfeldt KE. S100A9 differentially modifies phenotypic states of neutrophils, macrophages, and dendritic cells: implications for atherosclerosis and adipose tissue inflammation. Circulation. 123: 1216-26. PMID 21382888 DOI: 10.1161/Circulationaha.110.985523  0.318
2010 Suzuki M, Pritchard DK, Becker L, Hoofnagle AN, Tanimura N, Bammler TK, Beyer RP, Bumgarner R, Vaisar T, de Beer MC, de Beer FC, Miyake K, Oram JF, Heinecke JW. High-density lipoprotein suppresses the type I interferon response, a family of potent antiviral immunoregulators, in macrophages challenged with lipopolysaccharide. Circulation. 122: 1919-27. PMID 20974999 DOI: 10.1161/Circulationaha.110.961193  0.391
2010 Becker L, Gharib SA, Irwin AD, Wijsman E, Vaisar T, Oram JF, Heinecke JW. A macrophage sterol-responsive network linked to atherogenesis. Cell Metabolism. 11: 125-35. PMID 20142100 DOI: 10.1016/J.Cmet.2010.01.003  0.321
2006 Becker L, Nesheim ME, Koschinsky ML. Catalysis of covalent Lp(a) assembly: evidence for an extracellular enzyme activity that enhances disulfide bond formation. Biochemistry. 45: 9919-28. PMID 16893192 DOI: 10.1021/Bi060283T  0.559
2005 Devlin CM, Lee SJ, Kuriakose G, Spencer C, Becker L, Grosskopf I, Ko C, Huang LS, Koschinsky ML, Cooper AD, Tabas I. An apolipoprotein(a) peptide delays chylomicron remnant clearance and increases plasma remnant lipoproteins and atherosclerosis in vivo. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 1704-10. PMID 15905467 DOI: 10.1161/01.Atv.0000170819.57945.03  0.58
2004 Becker L, Cook PM, Koschinsky ML. Identification of sequences in apolipoprotein(a) that maintain its closed conformation: a novel role for apo(a) isoform size in determining the efficiency of covalent Lp(a) formation. Biochemistry. 43: 9978-88. PMID 15287725 DOI: 10.1021/bi049536d  0.611
2004 Becker L, Cook PM, Wright TG, Koschinsky ML. Quantitative evaluation of the contribution of weak lysine-binding sites present within apolipoprotein(a) kringle IV types 6-8 to lipoprotein(a) assembly. The Journal of Biological Chemistry. 279: 2679-88. PMID 14581473 DOI: 10.1074/Jbc.M309414200  0.607
2003 Hill BC, Becker L, Anand V, Kusmierczyk A, Marcovina SM, Rahman MN, Gabel BR, Jia Z, Boffa MB, Koschinsky ML. A role for apolipoprotein(a) in protection of the low-density lipoprotein component of lipoprotein(a) from copper-mediated oxidation. Archives of Biochemistry and Biophysics. 412: 186-95. PMID 12667482 DOI: 10.1016/S0003-9861(03)00032-8  0.691
2003 Becker L, Webb BA, Chitayat S, Nesheim ME, Koschinsky ML. A ligand-induced conformational change in apolipoprotein(a) enhances covalent Lp(a) formation. The Journal of Biological Chemistry. 278: 14074-81. PMID 12566443 DOI: 10.1074/Jbc.M212855200  0.595
2002 Nesheim M, Samis J, Walker J, Becker L, Brufatto N, Fischer T, Tejidor L, Jones G, Houdijk W, Giles A, Koschinsky M, Wenstone R, Downey C, Toh CH. Lipoprotein-complexed C-reactive protein and the biphasic transmittance waveform in critically ill patients Blood Reviews. 16: S15-22. PMID 12918783  0.552
2002 Toh CH, Samis J, Downey C, Walker J, Becker L, Brufatto N, Tejidor L, Jones G, Houdijk W, Giles A, Koschinsky M, Ticknor LO, Paton R, Wenstone R, Nesheim M. Biphasic transmittance waveform in the APTT coagulation assay is due to the formation of a Ca ++-dependent complex of C-reactive protein with very-low-density lipoprotein and is a novel marker of impending disseminated intravascular coagulation Blood. 100: 2522-2529. PMID 12239165 DOI: 10.1182/Blood.V100.7.2522  0.576
2002 Rahman MN, Becker L, Petrounevitch V, Hill BC, Jia Z, Koschinsky ML. Comparative analyses of the lysine binding site properties of apolipoprotein(a) kringle IV types 7 and 10. Biochemistry. 41: 1149-55. PMID 11802713 DOI: 10.1021/Bi010964I  0.692
2001 Becker L, Gabel BR, Spencer CA, Marcovina SM, Koschinsky ML. Effect of low-density lipoprotein buoyant density and cholesterol content on the formation of lipoprotein(a) particles. Clinical and Experimental Medicine. 1: 121-5. PMID 11699729 DOI: 10.1007/S10238-001-8022-3  0.577
2001 Becker L, McLeod RS, Marcovina SM, Yao Z, Koschinsky ML. Identification of a critical lysine residue in apolipoprotein B-100 that mediates noncovalent interaction with apolipoprotein(a). The Journal of Biological Chemistry. 276: 36155-62. PMID 11473115 DOI: 10.1074/Jbc.M104789200  0.621
2001 Nesheim M, Samis J, Walker J, Fischer T, Tejidor L, Jones G, Houdijk W, Giles A, Becker L, Koschinsky M, Wenstone R, Downey C, Toh CH. The formation of a CA2+-dependent complex of C-reactive protein and very low density lipoprotein causes the biphasic transmittance waveform Bmc News and Views. 1. DOI: 10.1186/1471-2210-7-S1-P42  0.536
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