Isabelle Mercier, Ph.D. - Publications

Affiliations: 
2004 Université de Montréal, Montréal, Canada 
Area:
Molecular Biology, Biochemistry

36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Dees S, Pontiggia L, Jasmin JF, Mercier I. Phosphorylated STAT3 (Tyr705) as a biomarker of response to pimozide treatment in triple-negative breast cancer. Cancer Biology & Therapy. 1-16. PMID 32164483 DOI: 10.1080/15384047.2020.1726718  0.343
2020 Chilewski SD, Bhosale D, Dees S, Hutchinson I, Trimble R, Pontiggia L, Mercier I, Jasmin JF. Development of CAPER peptides for the treatment of triple negative breast cancer. Cell Cycle (Georgetown, Tex.). 1-16. PMID 31931653 DOI: 10.1080/15384101.2020.1711579  0.393
2018 Campbell MC, Pontiggia L, Russell AY, Schwarting R, Camacho J, Jasmin JF, Mercier I. CAPER as a therapeutic target for triple negative breast cancer. Oncotarget. 9: 30340-30354. PMID 30100993 DOI: 10.18632/Oncotarget.25719  0.421
2018 Fultang N, Klase Z, Mercier I, Peethambaran B. Abstract P5-07-13: MicroRNA-mediated restoration of tamoxifen sensitivity in triple negative breast cancer through modulation of estrogen receptor alpha/beta ratio using Myrothamnus flabellifolius Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P5-07-13  0.406
2014 Mercier I, Gonzales DM, Quann K, Pestell TG, Molchansky A, Sotgia F, Hulit J, Gandara R, Wang C, Pestell RG, Lisanti MP, Jasmin JF. CAPER, a novel regulator of human breast cancer progression. Cell Cycle (Georgetown, Tex.). 13: 1256-64. PMID 24621503 DOI: 10.4161/Cc.28156  0.402
2013 Danilo C, Gutierrez-Pajares JL, Mainieri MA, Mercier I, Lisanti MP, Frank PG. Scavenger receptor class B type I regulates cellular cholesterol metabolism and cell signaling associated with breast cancer development Breast Cancer Research. 15. PMID 24060386 DOI: 10.1186/Bcr3483  0.397
2013 Quann K, Gonzales DM, Mercier I, Wang C, Sotgia F, Pestell RG, Lisanti MP, Jasmin JF. Caveolin-1 is a negative regulator of tumor growth in glioblastoma and modulates chemosensitivity to temozolomide Cell Cycle. 12: 1510-1520. PMID 23598719 DOI: 10.4161/Cc.24497  0.336
2012 Mercier I, Camacho J, Titchen K, Gonzales DM, Quann K, Bryant KG, Molchansky A, Milliman JN, Whitaker-Menezes D, Sotgia F, Jasmin JF, Schwarting R, Pestell RG, Blagosklonny MV, Lisanti MP. Caveolin-1 and accelerated host aging in the breast tumor microenvironment: chemoprevention with rapamycin, an mTOR inhibitor and anti-aging drug. The American Journal of Pathology. 181: 278-93. PMID 22698676 DOI: 10.1016/J.Ajpath.2012.03.017  0.326
2012 Mercier I, Lisanti MP. Caveolin-1 and breast cancer: a new clinical perspective. Advances in Experimental Medicine and Biology. 729: 83-94. PMID 22411315 DOI: 10.1007/978-1-4614-1222-9_6  0.356
2011 Bryant KG, Camacho J, Jasmin JF, Wang C, Addya S, Casimiro MC, Fortina P, Balasubramaniam S, Knudsen KE, Schwarting R, Lisanti MP, Mercier I. Caveolin-1 overexpression enhances androgen-dependent growth and proliferation in the mouse prostate. The International Journal of Biochemistry & Cell Biology. 43: 1318-29. PMID 21601007 DOI: 10.1016/J.Biocel.2011.04.019  0.311
2011 Llaverias G, Danilo C, Mercier I, Daumer K, Capozza F, Williams TM, Sotgia F, Lisanti MP, Frank PG. Role of cholesterol in the development and progression of breast cancer. The American Journal of Pathology. 178: 402-12. PMID 21224077 DOI: 10.1016/J.Ajpath.2010.11.005  0.328
2011 Rivadeneira D, Mercier I, Lisanti MP, Witkiewicz A, Knudsen ES. Abstract 233: Crosstalk of Her2 signaling and cell cycle control in the response to targeted therapeutics in breast cancer Cancer Research. 71: 233-233. DOI: 10.1158/1538-7445.Am2011-233  0.412
2010 Martinez-Outschoorn UE, Whitaker-Menezes D, Pavlides S, Chiavarina B, Bonuccelli G, Casey T, Tsirigos A, Migneco G, Witkiewicz A, Balliet R, Mercier I, Wang C, Flomenberg N, Howell A, Lin Z, et al. The autophagic tumor stroma model of cancer or "battery-operated tumor growth": A simple solution to the autophagy paradox. Cell Cycle (Georgetown, Tex.). 9: 4297-306. PMID 21051947 DOI: 10.4161/Cc.9.21.13817  0.325
2010 Rivadeneira D, Ertel A, Witkiewicz A, Mercier I, Lisanti M, Knudsen E. Abstract P4-01-04: The Impact of the Retinoblastoma Tumor Suppressor Pathway in Her2 Positive Breast Cancer Pathogenesis and Therapeutic Response Cancer Research. 70. DOI: 10.1158/0008-5472.Sabcs10-P4-01-04  0.386
2009 Witkiewicz AK, Casimiro MC, Dasgupta A, Mercier I, Wang C, Bonuccelli G, Jasmin JF, Frank PG, Pestell RG, Kleer CG, Sotgia F, Lisanti MP. Towards a new "stromal-based" classification system for human breast cancer prognosis and therapy. Cell Cycle (Georgetown, Tex.). 8: 1654-8. PMID 19448435 DOI: 10.4161/Cc.8.11.8544  0.365
2009 Witkiewicz AK, Dasgupta A, Sotgia F, Mercier I, Pestell RG, Sabel M, Kleer CG, Brody JR, Lisanti MP. An absence of stromal caveolin-1 expression predicts early tumor recurrence and poor clinical outcome in human breast cancers. The American Journal of Pathology. 174: 2023-34. PMID 19411448 DOI: 10.2353/Ajpath.2009.080873  0.37
2009 Bonuccelli G, Casimiro MC, Sotgia F, Wang C, Liu M, Katiyar S, Zhou J, Dew E, Capozza F, Daumer KM, Minetti C, Milliman JN, Alpy F, Rio MC, Tomasetto C, ... Mercier I, et al. Caveolin-1 (P132L), a common breast cancer mutation, confers mammary cell invasiveness and defines a novel stem cell/metastasis-associated gene signature. The American Journal of Pathology. 174: 1650-62. PMID 19395651 DOI: 10.2353/Ajpath.2009.080648  0.369
2009 Mercier I, Bryant KG, Sotgia F, Bonuccelli G, Witkiewicz AK, Dasgupta A, Jasmin JF, Pestell RG, Lisanti MP. Using Caveolin-1 epithelial immunostaining patterns to stratify human breast cancer patients and predict the Caveolin-1 (P132L) mutation Cell Cycle. 8: 1396-1401. PMID 19342880 DOI: 10.4161/Cc.8.9.8307  0.302
2009 Mercier I, Casimiro MC, Zhou J, Wang C, Plymire C, Bryant KG, Daumer KM, Sotgia F, Bonuccelli G, Witkiewicz AK, Lin J, Tran TH, Milliman J, Frank PG, Jasmin JF, et al. Genetic ablation of caveolin-1 drives estrogen-hypersensitivity and the development of DCIS-like mammary lesions. The American Journal of Pathology. 174: 1172-90. PMID 19342371 DOI: 10.2353/Ajpath.2009.080882  0.383
2009 Mercier I, Jasmin JF, Pavlides S, Minetti C, Flomenberg N, Pestell RG, Frank PG, Sotgia F, Lisanti MP. Clinical and translational implications of the caveolin gene family: lessons from mouse models and human genetic disorders. Laboratory Investigation; a Journal of Technical Methods and Pathology. 89: 614-23. PMID 19333235 DOI: 10.1038/Labinvest.2009.23  0.309
2009 Sotgia F, Del Galdo F, Casimiro MC, Bonuccelli G, Mercier I, Whitaker-Menezes D, Daumer KM, Zhou J, Wang C, Katiyar S, Xu H, Bosco E, Quong AA, Aronow B, Witkiewicz AK, et al. Caveolin-1-/- null mammary stromal fibroblasts share characteristics with human breast cancer-associated fibroblasts. The American Journal of Pathology. 174: 746-61. PMID 19234134 DOI: 10.2353/Ajpath.2009.080658  0.403
2009 Sotgia F, Casimiro MC, Bonuccelli G, Liu M, Whitaker-Menezes D, Er O, Daumer KM, Mercier I, Witkiewicz AK, Minetti C, Capozza F, Gormley M, Quong AA, Rui H, Frank PG, et al. Loss of caveolin-3 induces a lactogenic microenvironment that is protective against mammary tumor formation. The American Journal of Pathology. 174: 613-29. PMID 19164602 DOI: 10.2353/Ajpath.2009.080653  0.364
2008 Mercier I, Vuolo M, Jasmin JF, Medina CM, Williams M, Mariadason JM, Qian H, Xue X, Pestell RG, Lisanti MP, Kitsis RN. ARC (apoptosis repressor with caspase recruitment domain) is a novel marker of human colon cancer Cell Cycle. 7: 1640-1647. PMID 18469522 DOI: 10.4161/Cc.7.11.5979  0.347
2008 Mercier I, Casimiro MC, Wang C, Rosenberg AL, Quong J, Minkeu A, Allen KG, Danilo C, Sotgia F, Bonuccelli G, Jasmin JF, Xu H, Bosco E, Aronow B, Witkiewicz A, et al. Human breast cancer-associated fibroblasts (CAFs) show caveolin-1 downregulation and RB tumor suppressor functional inactivation: Implications for the response to hormonal therapy Cancer Biology and Therapy. 7: 1212-1225. PMID 18458534 DOI: 10.4161/Cbt.7.8.6220  0.386
2006 Sotgia F, Rui H, Bonuccelli G, Mercier I, Pestell RG, Lisanti MP. Caveolin-1, mammary stem cells, and estrogen-dependent breast cancers. Cancer Research. 66: 10647-51. PMID 17108100 DOI: 10.1158/0008-5472.Can-06-2805  0.428
2006 Williams TM, Sotgia F, Lee H, Hassan G, Di Vizio D, Bonuccelli G, Capozza F, Mercier I, Rui H, Pestell RG, Lisanti MP. Stromal and epithelial caveolin-1 both confer a protective effect against mammary hyperplasia and tumorigenesis: Caveolin-1 antagonizes cyclin D1 function in mammary epithelial cells. The American Journal of Pathology. 169: 1784-801. PMID 17071600 DOI: 10.2353/Ajpath.2006.060590  0.373
2005 Mercier I, Vuolo M, Madan R, Xue X, Levalley AJ, Ashton AW, Jasmin JF, Czaja MT, Lin EY, Armstrong RC, Pollard JW, Kitsis RN. ARC, an apoptosis suppressor limited to terminally differentiated cells, is induced in human breast cancer and confers chemo- and radiation-resistance. Cell Death and Differentiation. 12: 682-6. PMID 15861191 DOI: 10.1038/Sj.Cdd.4401631  0.304
2003 Pham-Dang ML, Clement R, Mercier I, Calderone A. Comparative effects of tamoxifen and angiotensin II type-1 receptor antagonist therapy on the hemodynamic profile of the ovariectomized female rat. Canadian Journal of Physiology and Pharmacology. 81: 915-9. PMID 14614530 DOI: 10.1139/Y03-086  0.599
2003 Thorin E, Pham-Dang M, Clement R, Mercier I, Calderone A. Hyper-reactivity of cerebral arteries from ovariectomized rats: therapeutic benefit of tamoxifen. British Journal of Pharmacology. 140: 1187-92. PMID 14597597 DOI: 10.1038/Sj.Bjp.0705547  0.593
2003 Mercier I, Mader S, Calderone A. Tamoxifen and ICI 182,780 negatively influenced cardiac cell growth via an estrogen receptor-independent mechanism. Cardiovascular Research. 59: 883-92. PMID 14553828 DOI: 10.1016/S0008-6363(03)00517-0  0.616
2002 Mercier I, Pham-Dang M, Clement R, Gosselin H, Colombo F, Rouleau JL, Calderone A. Elevated mean arterial pressure in the ovariectomized rat was normalized by ET(A) receptor antagonist therapy: absence of cardiac hypertrophy and fibrosis. British Journal of Pharmacology. 136: 685-92. PMID 12086977 DOI: 10.1038/Sj.Bjp.0704765  0.616
2002 Sanchez R, MacKenzie A, Farhat N, Nguyen TD, Stewart DJ, Mercier I, Calderone A, Thorin E. Endothelin B receptor-mediated regulation of endothelin-1 content and release in cultured porcine aorta endothelial cell. Journal of Cardiovascular Pharmacology. 39: 652-9. PMID 11973408 DOI: 10.1097/00005344-200205000-00005  0.575
2002 Mercier I, Colombo F, Mader S, Calderone A. Ovarian hormones induce TGF-beta(3) and fibronectin mRNAs but exhibit a disparate action on cardiac fibroblast proliferation. Cardiovascular Research. 53: 728-39. PMID 11861043 DOI: 10.1016/S0008-6363(01)00525-9  0.609
2001 Abdelaziz N, Colombo F, Mercier I, Calderone A. Nitric oxide attenuates the expression of transforming growth factor-beta(3) mRNA in rat cardiac fibroblasts via destabilization. Hypertension. 38: 261-6. PMID 11509487 DOI: 10.1161/01.Hyp.38.2.261  0.588
2001 Colombo F, Noël J, Mayers P, Mercier I, Calderone A. beta-Adrenergic stimulation of rat cardiac fibroblasts promotes protein synthesis via the activation of phosphatidylinositol 3-kinase. Journal of Molecular and Cellular Cardiology. 33: 1091-106. PMID 11444915 DOI: 10.1006/Jmcc.2001.1381  0.605
1998 Eng FC, Barsalou A, Akutsu N, Mercier I, Zechel C, Mader S, White JH. Different classes of coactivators recognize distinct but overlapping binding sites on the estrogen receptor ligand binding domain. The Journal of Biological Chemistry. 273: 28371-7. PMID 9774463 DOI: 10.1074/Jbc.273.43.28371  0.343
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