| Year |
Citation |
Score |
| 2018 |
Clynes RA, Desjarlais JR. Redirected T Cell Cytotoxicity in Cancer Therapy. Annual Review of Medicine. PMID 30379598 DOI: 10.1146/annurev-med-062617-035821 |
0.342 |
|
| 2018 |
de Jong A, Jabbari A, Dai Z, Xing L, Lee D, Li MM, Duvic M, Hordinsky M, Norris DA, Price V, Mackay-Wiggan J, Clynes R, Christiano AM. High-throughput T cell receptor sequencing identifies clonally expanded CD8+ T cell populations in alopecia areata. Jci Insight. 3. PMID 30282836 DOI: 10.1172/Jci.Insight.121949 |
0.408 |
|
| 2018 |
Norton N, Fox N, McCarl CA, Tenner KS, Ballman K, Erskine CL, Necela BM, Northfelt D, Tan WW, Calfa C, Pegram M, Colon-Otero G, Perez EA, Clynes R, Knutson KL. Generation of HER2-specific antibody immunity during trastuzumab adjuvant therapy associates with reduced relapse in resected HER2 breast cancer. Breast Cancer Research : Bcr. 20: 52. PMID 29898752 DOI: 10.1186/S13058-018-0989-8 |
0.304 |
|
| 2018 |
Jabbari A, Sansaricq F, Cerise J, Chen JC, Bitterman A, Ulerio G, Borbon J, Clynes R, Christiano AM, Mackay-Wiggan J. An Open-Label Pilot Study to Evaluate the Efficacy of Tofacitinib in Moderate to Severe Patch Type Alopecia Areata, Totalis and Universalis. The Journal of Investigative Dermatology. PMID 29452121 DOI: 10.1016/J.Jid.2018.01.032 |
0.341 |
|
| 2018 |
Perez-Lorenzo R, Erjavec S, Clynes R, Christiano A. 1210 Enhancing the therapeutic efficacy of immune checkpoint inhibition and targeted therapy using anti-tumor antibodies in mouse melanoma Journal of Investigative Dermatology. 138: S205. DOI: 10.1016/J.Jid.2018.03.1225 |
0.372 |
|
| 2017 |
Clynes R, Dai Z, Cerise J, Christiano A. 054 Regulatory natural killer cells are protective in alopecia areata Journal of Investigative Dermatology. 137: S9. DOI: 10.1016/J.Jid.2017.02.067 |
0.374 |
|
| 2017 |
de Jong A, Jabbari A, Dai Z, Xing L, Lee D, Price V, Duvic M, Norris D, Hordinsky M, Mackay-Wiggan J, Clynes R, Christiano A. 052 Identification of pathogenic T cell subsets in human alopecia areata Journal of Investigative Dermatology. 137: S9. DOI: 10.1016/J.Jid.2017.02.065 |
0.364 |
|
| 2016 |
Mackay-Wiggan J, Jabbari A, Nguyen N, Cerise JE, Clark C, Ulerio G, Furniss M, Vaughan R, Christiano AM, Clynes R. Oral ruxolitinib induces hair regrowth in patients with moderate-to-severe alopecia areata. Jci Insight. 1: e89790. PMID 27699253 DOI: 10.1172/Jci.Insight.89790 |
0.303 |
|
| 2016 |
Dai Z, Xing L, Cerise J, Wang EH, Jabbari A, de Jong A, Petukhova L, Christiano AM, Clynes R. CXCR3 Blockade Inhibits T Cell Migration into the Skin and Prevents Development of Alopecia Areata. Journal of Immunology (Baltimore, Md. : 1950). PMID 27412416 DOI: 10.4049/Jimmunol.1501798 |
0.44 |
|
| 2016 |
Jabbari A, Cerise JE, Chen JC, Mackay-Wiggan J, Duvic M, Price V, Hordinsky M, Norris D, Clynes R, Christiano AM. Molecular signatures define alopecia areata subtypes and transcriptional biomarkers. Ebiomedicine. 7: 240-247. PMID 27322477 DOI: 10.1016/J.Ebiom.2016.03.036 |
0.322 |
|
| 2016 |
Knutson KL, Clynes R, Shreeder B, Yeramian P, Kemp K, Ballman K, Tenner KS, Erskine CL, Norton N, Northfelt DW, Tan W, Calfa C, Pegram MD, Mittendorf EA, Perez EA. Improved survival of HER2+ breast cancer patients treated with trastuzumab and chemotherapy is associated with host antibody immunity against the HER2 intracellular domain. Cancer Research. PMID 27197192 DOI: 10.1158/0008-5472.Can-15-3091 |
0.329 |
|
| 2016 |
Dai Z, Cerise J, de Jong A, Clynes R, Christiano A. 043 Regulatory natural killer cells in alopecia areata Journal of Investigative Dermatology. 136: S8. DOI: 10.1016/J.Jid.2016.02.068 |
0.369 |
|
| 2016 |
de Jong A, Xing L, Jabbari A, Dai Z, Lee D, Price V, Duvic M, Norris D, Hordinsky M, Mackay-Wiggan J, Clynes R, Christiano A. 006 Correlation between frequency of circulating lesional T cell clones and disease severity in human Alopecia Areata Journal of Investigative Dermatology. 136: S1. DOI: 10.1016/J.Jid.2016.02.030 |
0.304 |
|
| 2015 |
Chen JC, Cerise JE, Jabbari A, Clynes R, Christiano AM. Master regulators of infiltrate recruitment in autoimmune disease identified through network-based molecular deconvolution. Cell Systems. 1: 326-337. PMID 26665180 DOI: 10.1016/J.Cels.2015.11.001 |
0.314 |
|
| 2015 |
Flynn R, Allen JL, Luznik L, MacDonald KP, Paz K, Alexander KA, Vulic A, Du J, Panoskaltsis-Mortari A, Taylor PA, Poe JC, Serody JS, Murphy WJ, Hill GR, Maillard I, ... ... Clynes RA, et al. Targeting Syk-activated B cells in murine and human chronic graft-versus-host disease. Blood. 125: 4085-94. PMID 25852057 DOI: 10.1182/Blood-2014-08-595470 |
0.317 |
|
| 2015 |
Flores M, Chew C, Tyan K, Huang WQ, Salem A, Clynes R. FcγRIIB prevents inflammatory type I IFN production from plasmacytoid dendritic cells during a viral memory response. Journal of Immunology (Baltimore, Md. : 1950). 194: 4240-50. PMID 25821224 DOI: 10.4049/Jimmunol.1401296 |
0.679 |
|
| 2015 |
Betz RC, Petukhova L, Ripke S, Huang H, Menelaou A, Redler S, Becker T, Heilmann S, Yamany T, Duvic M, Hordinsky M, Norris D, Price VH, Mackay-Wiggan J, de Jong A, ... ... Clynes R, et al. Genome-wide meta-analysis in alopecia areata resolves HLA associations and reveals two new susceptibility loci. Nature Communications. 6: 5966. PMID 25608926 DOI: 10.1038/Ncomms6966 |
0.339 |
|
| 2014 |
Xing L, Dai Z, Jabbari A, Cerise JE, Higgins CA, Gong W, de Jong A, Harel S, DeStefano GM, Rothman L, Singh P, Petukhova L, Mackay-Wiggan J, Christiano AM, Clynes R. Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition. Nature Medicine. 20: 1043-9. PMID 25129481 DOI: 10.1038/Nm.3645 |
0.477 |
|
| 2014 |
Akirav EM, Henegariu O, Preston-Hurlburt P, Schmidt AM, Clynes R, Herold KC. The receptor for advanced glycation end products (RAGE) affects T cell differentiation in OVA induced asthma. Plos One. 9: e95678. PMID 24759895 DOI: 10.1371/journal.pone.0095678 |
0.404 |
|
| 2013 |
Henle AM, Erskine CL, Benson LM, Clynes R, Knutson KL. Enzymatic discovery of a HER-2/neu epitope that generates cross-reactive T cells. Journal of Immunology (Baltimore, Md. : 1950). 190: 479-88. PMID 23180824 DOI: 10.4049/Jimmunol.1201264 |
0.309 |
|
| 2013 |
Knutson KL, Perez EA, Ballman KV, Erskine CL, Fox N, McCarl C, Norton N, Sumrall SV, Northfelt DW, Tan W, Calfa CJ, Pegram MD, Clynes R. Generation of adaptive HER2-specific immunity in HER2 breast cancer patients by addition of trastuzumab to chemotherapy in the adjuvant setting: NCCTG (Alliance) study N9831. Journal of Clinical Oncology. 31: 522-522. DOI: 10.1200/Jco.2013.31.15_Suppl.522 |
0.33 |
|
| 2013 |
Clynes R, Knutson KL, Ballman KV, Erskine CL, Norton N, Sumrall SV, Northfelt DW, Tan W, Calfa CJ, Pegram MD, Perez EA. Combination trastuzumab and chemotherapy to induce immunity to multiple tumor antigens in patients with HER2-positive metastatic breast cancer: NCCTG (Alliance) studies N0337 and N98-32-52. Journal of Clinical Oncology. 31: 521-521. DOI: 10.1200/Jco.2013.31.15_Suppl.521 |
0.357 |
|
| 2012 |
Akirav EM, Preston-Hurlburt P, Garyu J, Henegariu O, Clynes R, Schmidt AM, Herold KC. RAGE expression in human T cells: a link between environmental factors and adaptive immune responses. Plos One. 7: e34698. PMID 22509345 DOI: 10.1371/Journal.Pone.0034698 |
0.492 |
|
| 2011 |
Song S, Chew C, Dale BM, Traum D, Peacock J, Yamazaki T, Clynes R, Kurosaki T, Greenberg S. A requirement for the p85 PI3K adapter protein BCAP in the protection of macrophages from apoptosis induced by endoplasmic reticulum stress. Journal of Immunology (Baltimore, Md. : 1950). 187: 619-25. PMID 21685326 DOI: 10.4049/Jimmunol.0903425 |
0.386 |
|
| 2011 |
Colonna L, Catalano G, Chew C, D'Agati V, Thomas JW, Wong FS, Schmitz J, Masuda ES, Reizis B, Tarakhovsky A, Clynes R. Therapeutic targeting of Syk in autoimmune diabetes (Journal of Immunology 185 (1532-1543)) Journal of Immunology. 187: 1516. DOI: 10.4049/Jimmunol.1190038 |
0.631 |
|
| 2011 |
Colonna L, Clynes R. Response to comment on "therapeutic targeting of Syk in autoimmune diabetes", Journal of Immunology. 186: 1885-1886. DOI: 10.4049/Jimmunol.1090141 |
0.55 |
|
| 2010 |
Colonna L, Catalano G, Chew C, D'Agati V, Thomas JW, Wong FS, Schmitz J, Masuda ES, Reizis B, Tarakhovsky A, Clynes R. Therapeutic targeting of Syk in autoimmune diabetes. Journal of Immunology (Baltimore, Md. : 1950). 185: 1532-43. PMID 20601600 DOI: 10.4049/Jimmunol.1000983 |
0.714 |
|
| 2010 |
Budhu S, Loike JD, Pandolfi A, Han S, Catalano G, Constantinescu A, Clynes R, Silverstein SC. CD8+ T cell concentration determines their efficiency in killing cognate antigen-expressing syngeneic mammalian cells in vitro and in mouse tissues. The Journal of Experimental Medicine. 207: 223-35. PMID 20065066 DOI: 10.1084/Jem.20091279 |
0.595 |
|
| 2009 |
Flores M, Desai DD, Downie M, Liang B, Reilly MP, McKenzie SE, Clynes R. Dominant expression of the inhibitory FcgammaRIIB prevents antigen presentation by murine plasmacytoid dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 183: 7129-39. PMID 19917701 DOI: 10.4049/Jimmunol.0901169 |
0.753 |
|
| 2008 |
Chen Y, Akirav EM, Chen W, Henegariu O, Moser B, Desai D, Shen JM, Webster JC, Andrews RC, Mjalli AM, Rothlein R, Schmidt AM, Clynes R, Herold KC. RAGE ligation affects T cell activation and controls T cell differentiation. Journal of Immunology (Baltimore, Md. : 1950). 181: 4272-8. PMID 18768885 DOI: 10.4049/Jimmunol.181.6.4272 |
0.485 |
|
| 2008 |
Ramasamy R, Yan SF, Herold K, Clynes R, Schmidt AM. Receptor for advanced glycation end products: fundamental roles in the inflammatory response: winding the way to the pathogenesis of endothelial dysfunction and atherosclerosis. Annals of the New York Academy of Sciences. 1126: 7-13. PMID 18448789 DOI: 10.1196/Annals.1433.056 |
0.386 |
|
| 2008 |
Liang B, Workman C, Lee J, Chew C, Dale BM, Colonna L, Flores M, Li N, Schweighoffer E, Greenberg S, Tybulewicz V, Vignali D, Clynes R. Regulatory T cells inhibit dendritic cells by lymphocyte activation gene-3 engagement of MHC class II. Journal of Immunology (Baltimore, Md. : 1950). 180: 5916-26. PMID 18424711 DOI: 10.4049/Jimmunol.180.9.5916 |
0.762 |
|
| 2008 |
Colonna L, Thomas J, Masuda E, Clynes R. OR.50. Targeting Syk in Autoimmune Diabetes Clinical Immunology. 127: S21-S22. DOI: 10.1016/J.Clim.2008.03.056 |
0.522 |
|
| 2007 |
Clynes R, Moser B, Yan SF, Ramasamy R, Herold K, Schmidt AM. Receptor for AGE (RAGE): Weaving tangled webs within the inflammatory response Current Molecular Medicine. 7: 743-751. PMID 18331232 DOI: 10.2174/156652407783220714 |
0.369 |
|
| 2007 |
Clynes R, Herold K, Schmidt AM. RAGE: Exacting a toll on the host in response to polymicrobial sepsis and Listeria monocytogenes Critical Care. 11. PMID 18190725 DOI: 10.1186/Cc6193 |
0.425 |
|
| 2007 |
Moser B, Desai DD, Downie MP, Chen Y, Shi FY, Herold K, Schmidt AM, Clynes R. Receptor for advanced glycation end products expression on T cells contributes to antigen-specific cellular expansion in vivo Journal of Immunology. 179: 8051-8058. PMID 18056345 DOI: 10.4049/Jimmunol.179.12.8051 |
0.491 |
|
| 2007 |
Taylor C, Hershman D, Shah N, Suciu-Foca N, Petrylak DP, Taub R, Vahdat L, Cheng B, Pegram M, Knutson KL, Clynes R. Augmented HER-2 specific immunity during treatment with trastuzumab and chemotherapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 5133-43. PMID 17785568 DOI: 10.1158/1078-0432.Ccr-07-0507 |
0.404 |
|
| 2007 |
He LZ, Crocker A, Lee J, Mendoza-Ramirez J, Wang XT, Vitale LA, O'Neill T, Petromilli C, Zhang HF, Lopez J, Rohrer D, Keler T, Clynes R. Antigenic targeting of the human mannose receptor induces tumor immunity. Journal of Immunology (Baltimore, Md. : 1950). 178: 6259-67. PMID 17475854 DOI: 10.4049/Jimmunol.178.10.6259 |
0.502 |
|
| 2007 |
Desai DD, Harbers SO, Flores M, Colonna L, Downie MP, Bergtold A, Jung S, Clynes R. Fc gamma receptor IIB on dendritic cells enforces peripheral tolerance by inhibiting effector T cell responses. Journal of Immunology (Baltimore, Md. : 1950). 178: 6217-26. PMID 17475849 DOI: 10.4049/Jimmunol.178.10.6217 |
0.73 |
|
| 2007 |
Harbers SO, Crocker A, Catalano G, D'Agati V, Jung S, Desai DD, Clynes R. Antibody-enhanced cross-presentation of self antigen breaks T cell tolerance. The Journal of Clinical Investigation. 117: 1361-9. PMID 17446931 DOI: 10.1172/Jci29470 |
0.663 |
|
| 2007 |
Clynes R. IVIG therapy: interfering with interferon-gamma. Immunity. 26: 4-6. PMID 17241954 DOI: 10.1016/J.Immuni.2007.01.006 |
0.394 |
|
| 2006 |
Bergtold A, Gavhane A, D'Agati V, Madaio M, Clynes R. FcR-bearing myeloid cells are responsible for triggering murine lupus nephritis. Journal of Immunology (Baltimore, Md. : 1950). 177: 7287-95. PMID 17082647 DOI: 10.4049/Jimmunol.177.10.7287 |
0.747 |
|
| 2006 |
Clynes R. Antitumor antibodies in the treatment of cancer: Fc receptors link opsonic antibody with cellular immunity. Hematology/Oncology Clinics of North America. 20: 585-612. PMID 16762726 DOI: 10.1016/J.Hoc.2006.02.010 |
0.369 |
|
| 2005 |
Bergtold A, Desai DD, Gavhane A, Clynes R. Cell surface recycling of internalized antigen permits dendritic cell priming of B cells. Immunity. 23: 503-14. PMID 16286018 DOI: 10.1016/J.Immuni.2005.09.013 |
0.768 |
|
| 2005 |
Clynes R, Calvani N, Croker BP, Richards HB. Modulation of the immune response in pristane-induced lupus by expression of activation and inhibitory Fc receptors. Clinical and Experimental Immunology. 141: 230-7. PMID 15996187 DOI: 10.1111/J.1365-2249.2005.02847.X |
0.463 |
|
| 2005 |
Clynes R. Immune complexes as therapy for autoimmunity. The Journal of Clinical Investigation. 115: 25-7. PMID 15630438 DOI: 10.1172/Jci23994 |
0.376 |
|
| 2003 |
Curcio C, Di Carlo E, Clynes R, Smyth MJ, Boggio K, Quaglino E, Spadaro M, Colombo MP, Amici A, Lollini PL, Musiani P, Forni G. Nonredundant roles of antibody, cytokines, and perforin in the eradication of established Her-2/neu carcinomas. The Journal of Clinical Investigation. 111: 1161-70. PMID 12697735 DOI: 10.1172/Jci17426 |
0.422 |
|
| 2002 |
Trcka J, Moroi Y, Clynes RA, Goldberg SM, Bergtold A, Perales MA, Ma M, Ferrone CR, Carroll MC, Ravetch JV, Houghton AN. Redundant and alternative roles for activating Fc receptors and complement in an antibody-dependent model of autoimmune vitiligo. Immunity. 16: 861-8. PMID 12121667 DOI: 10.1016/S1074-7613(02)00327-8 |
0.744 |
|
| 2002 |
Rafiq K, Bergtold A, Clynes R. Immune complex-mediated antigen presentation induces tumor immunity. The Journal of Clinical Investigation. 110: 71-9. PMID 12093890 DOI: 10.1172/Jci15640 |
0.762 |
|
| 2001 |
Hatzivassiliou G, Miller I, Takizawa J, Palanisamy N, Rao PH, Iida S, Tagawa S, Taniwaki M, Russo J, Neri A, Cattoretti G, Clynes R, Mendelsohn C, Chaganti RS, Dalla-Favera R. IRTA1 and IRTA2, novel immunoglobulin superfamily receptors expressed in B cells and involved in chromosome 1q21 abnormalities in B cell malignancy. Immunity. 14: 277-89. PMID 11290337 DOI: 10.1016/S1074-7613(01)00109-1 |
0.338 |
|
| 1999 |
Fossati-Jimack L, Reininger L, Chicheportiche Y, Clynes R, Ravetch JV, Honjo T, Izui S. High Pathogenic Potential of Low-Affinity Autoantibodies in Experimental Autoimmune Hemolytic Anemia Journal of Experimental Medicine. 190: 1689-1696. PMID 10587359 DOI: 10.1084/Jem.190.11.1689 |
0.306 |
|
| 1999 |
Clynes R, Maizes JS, Guinamard R, Ono M, Takai T, Ravetch JV. Modulation of immune complex-induced inflammation in vivo by the coordinate expression of activation and inhibitory Fc receptors. The Journal of Experimental Medicine. 189: 179-85. PMID 9874574 DOI: 10.1084/Jem.189.1.179 |
0.432 |
|
| 1998 |
Weber LW, Bowne WB, Wolchok JD, Srinivasan R, Qin J, Moroi Y, Clynes R, Song P, Lewis JJ, Houghton AN. Tumor immunity and autoimmunity induced by immunization with homologous DNA. The Journal of Clinical Investigation. 102: 1258-64. PMID 9739060 DOI: 10.1172/Jci4004 |
0.479 |
|
| 1998 |
Clynes R, Dumitru C, Ravetch JV. Uncoupling of Immune Complex Formation and Kidney Damage in Autoimmune Glomerulonephritis Science. 279: 1052-1054. PMID 9461440 DOI: 10.1126/Science.279.5353.1052 |
0.379 |
|
| 1998 |
Clynes R, Takechi Y, Moroi Y, Houghton A, Ravetch JV. Fc receptors are required in passive and active immunity to melanoma Proceedings of the National Academy of Sciences of the United States of America. 95: 652-656. PMID 9435247 DOI: 10.1073/Pnas.95.2.652 |
0.457 |
|
| 1998 |
Long C, Rotman H, Kang Y, Daly T, Clynes R, Ravetch J. Humoral immune responses to the merozoite surface protein-1 of Plasmodium yoelii Parasitology International. 47: 70. DOI: 10.1016/S1383-5769(98)80130-X |
0.355 |
|
| 1997 |
Sutterwala FS, Noel GJ, Clynes R, Mosser DM. Selective suppression of interleukin-12 induction after macrophage receptor ligation Journal of Experimental Medicine. 185: 1977-1985. PMID 9166427 DOI: 10.1084/Jem.185.11.1977 |
0.304 |
|
| 1997 |
Sylvestre D, Clynes R, Ma M, Warren H, Carroll MC, Ravetch JV. Immunoglobulin G-mediated inflammatory responses develop normally in complement-deficient mice. The Journal of Experimental Medicine. 184: 2385-92. PMID 8976192 DOI: 10.1084/Jem.184.6.2385 |
0.451 |
|
| 1994 |
Takai T, Li M, Sylvestre D, Clynes R, Ravetch JV. FcR gamma chain deletion results in pleiotrophic effector cell defects. Cell. 76: 519-29. PMID 8313472 DOI: 10.1016/0092-8674(94)90115-5 |
0.484 |
|
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