| Year |
Citation |
Score |
| 2024 |
Kar M, Johnson KEE, Vanderheiden A, Elrod EJ, Floyd K, Geerling E, Stone ET, Salinas E, Banakis S, Wang W, Sathish S, Shrihari S, Davis-Gardner ME, Kohlmeier J, Pinto A, ... ... Grakoui A, et al. CD4+ and CD8+ T cells are required to prevent SARS-CoV-2 persistence in the nasal compartment. Biorxiv : the Preprint Server For Biology. PMID 38410446 DOI: 10.1101/2024.01.23.576505 |
0.472 |
|
| 2024 |
Gridley J, Holland B, Salinas E, Trivedi S, Dravid P, Elrod E, Jin F, Kumari A, Batista MN, Thapa M, Rice CM, Marcotrigiano J, Kapoor A, Grakoui A. Concerted synergy between viral-specific IgG and CD8+ T cells is critical for clearance of an HCV-related rodent hepacivirus. Hepatology (Baltimore, Md.). PMID 38214558 DOI: 10.1097/HEP.0000000000000753 |
0.531 |
|
| 2023 |
Dravid P, Murthy S, Attia Z, Cassady C, Chandra R, Trivedi S, Vyas A, Gridly J, Holland B, Kumari A, Grakoui A, Cullen JM, Walker CM, Sharma H, Kapoor A. Phenotype and fate of liver-resident CD8 T cells during acute and chronic hepacivirus infection. Plos Pathogens. 19: e1011697. PMID 37812637 DOI: 10.1371/journal.ppat.1011697 |
0.57 |
|
| 2023 |
Chaudhary S, Rai R, Pal PB, Tedesco D, Singhi AD, Monga SP, Grakoui A, Iyer SS, Raeman R. Western diet dampens T regulatory cell function to fuel hepatic inflammation in nonalcoholic fatty liver disease. Biorxiv : the Preprint Server For Biology. PMID 36993495 DOI: 10.1101/2023.03.23.533977 |
0.316 |
|
| 2022 |
Mazouz S, Salinas E, Bédard N, Filali A, Khedr O, Swadling L, Abdel-Hakeem MS, Siddique A, Barnes E, Bruneau J, Grakoui A, Shoukry NH. Differential immune transcriptomic profiles between vaccinated and resolved HCV reinfected subjects. Plos Pathogens. 18: e1010968. PMID 36378682 DOI: 10.1371/journal.ppat.1010968 |
0.414 |
|
| 2022 |
Nishio A, Hasan S, Park H, Park N, Salas JH, Salinas E, Kardava L, Juneau P, Frumento N, Massaccesi G, Moir S, Bailey JR, Grakoui A, Ghany MG, Rehermann B. Serum neutralization activity declines but memory B cells persist after cure of chronic hepatitis C. Nature Communications. 13: 5446. PMID 36114169 DOI: 10.1038/s41467-022-33035-z |
0.45 |
|
| 2022 |
Wolfisberg R, Thorselius CE, Salinas E, Elrod E, Trivedi S, Nielsen L, Fahnøe U, Kapoor A, Grakoui A, Rice CM, Bukh J, Holmbeck K, Scheel TKH. Neutralization and receptor usage of infectious culture derived rat hepacivirus as a model for hepatitis C. Hepatology (Baltimore, Md.). PMID 35445423 DOI: 10.1002/hep.32535 |
0.382 |
|
| 2021 |
Vanderheiden A, Thomas J, Soung AL, Davis-Gardner ME, Floyd K, Jin F, Cowan DA, Pellegrini K, Shi PY, Grakoui A, Klein RS, Bosinger SE, Kohlmeier JE, Menachery VD, Suthar MS. CCR2 Signaling Restricts SARS-CoV-2 Infection. Mbio. e0274921. PMID 34749524 DOI: 10.1128/mBio.02749-21 |
0.302 |
|
| 2021 |
Kumar A, Hossain RA, Yost SA, Bu W, Wang Y, Dearborn AD, Grakoui A, Cohen JI, Marcotrigiano J. Structural insights into hepatitis C virus receptor binding and entry. Nature. PMID 34526719 DOI: 10.1038/s41586-021-03913-5 |
0.338 |
|
| 2021 |
Cervantes-Barragan L, Vanderheiden A, Royer CJ, Davis-Gardner ME, Ralfs P, Chirkova T, Anderson LJ, Grakoui A, Suthar MS. Plasmacytoid dendritic cells produce type I interferon and reduce viral replication in airway epithelial cells after SARS-CoV-2 infection. Biorxiv : the Preprint Server For Biology. PMID 34013278 DOI: 10.1101/2021.05.12.443948 |
0.38 |
|
| 2021 |
Bremer W, Blasczyk H, Yin X, Duron ES, Grakoui A, Feng Z, Walker C. Resolution of hepatitis E virus infection in CD8+ T cell depleted rhesus macaques. Journal of Hepatology. PMID 33961939 DOI: 10.1016/j.jhep.2021.04.036 |
0.515 |
|
| 2021 |
Salinas E, Boisvert M, Upadhyay AA, Bédard N, Nelson SA, Bruneau J, Derdeyn CA, Marcotrigiano J, Evans MJ, Bosinger SE, Shoukry NH, Grakoui A. Early T follicular helper cell activity accelerates hepatitis C virus-specific B cell expansion. The Journal of Clinical Investigation. 131. PMID 33463551 DOI: 10.1172/JCI140590 |
0.463 |
|
| 2020 |
Stuart JD, Salinas E, Grakoui A. Immune system control of hepatitis C virus infection. Current Opinion in Virology. 46: 36-44. PMID 33137689 DOI: 10.1016/j.coviro.2020.10.002 |
0.48 |
|
| 2020 |
Vanderheiden A, Ralfs P, Chirkova T, Upadhyay AA, Zimmerman MG, Bedoya S, Aoued H, Tharp GM, Pellegrini KL, Manfredi C, Sorscher E, Mainou B, Lobby JL, Kohlmeier JE, Lowen AC, ... ... Grakoui A, et al. Type I and Type III IFN Restrict SARS-CoV-2 Infection of Human Airway Epithelial Cultures. Journal of Virology. PMID 32699094 DOI: 10.1128/Jvi.00985-20 |
0.402 |
|
| 2020 |
Chopyk DM, Grakoui A. Contribution of the Intestinal Microbiome and Gut Barrier to Hepatic Disorders. Gastroenterology. PMID 32569766 DOI: 10.1053/J.Gastro.2020.04.077 |
0.301 |
|
| 2020 |
Thapa M, Tedesco D, Gumber S, Elrod EJ, Han JH, Kitchens WH, Magliocca JF, Adams AB, Grakoui A. Blockade of BAFF Reshapes the Hepatic B Cell Receptor Repertoire and Attenuates Autoantibody Production in Cholestatic Liver Disease. Journal of Immunology (Baltimore, Md. : 1950). PMID 32332110 DOI: 10.4049/Jimmunol.1900391 |
0.426 |
|
| 2020 |
Rushdi M, Li K, Yuan Z, Travaglino S, Grakoui A, Zhu C. Mechanotransduction in T Cell Development, Differentiation and Function. Cells. 9. PMID 32033255 DOI: 10.3390/Cells9020364 |
0.414 |
|
| 2020 |
Coss SL, Torres-Cornejo A, Prasad MR, Moore-Clingenpeel M, Grakoui A, Lauer GM, Walker CM, Honegger JR. CD4+ T cell restoration and control of hepatitis C virus replication after childbirth. The Journal of Clinical Investigation. PMID 31904583 DOI: 10.1172/Jci123623 |
0.631 |
|
| 2018 |
Aguilar-Valenzuela R, Netland J, Seo YJ, Bevan MJ, Grakoui A, Suthar MS. Dynamics of tissue-specific CD8+ T cell responses during West Nile virus infection. Journal of Virology. PMID 29514902 DOI: 10.1128/Jvi.00014-18 |
0.564 |
|
| 2018 |
Tedesco D, Thapa M, Chin CY, Ge Y, Gong M, Li J, Gumber S, Speck P, Elrod EJ, Burd EM, Kitchens WH, Magliocca JF, Adams AB, Weiss DS, Mohamadzadeh M, ... Grakoui A, et al. Alterations in Intestinal Microbiota Lead to Production of Interleukin 17 by Intrahepatic γδ T-cell Receptor-positive Cells and Pathogenesis of Cholestatic Liver Disease. Gastroenterology. PMID 29454797 DOI: 10.1053/J.Gastro.2018.02.019 |
0.365 |
|
| 2018 |
Mimche PN, Lee CM, Mimche SM, Thapa M, Grakoui A, Henkemeyer M, Lamb TJ. EphB2 receptor tyrosine kinase promotes hepatic fibrogenesis in mice via activation of hepatic stellate cells. Scientific Reports. 8: 2532. PMID 29416088 DOI: 10.1038/S41598-018-20926-9 |
0.353 |
|
| 2017 |
Grakoui A, Walker CM. Of mice, rats and men: Small animal model of hepatitis C virus infection. Hepatology (Baltimore, Md.). PMID 29281849 DOI: 10.1002/Hep.29765 |
0.425 |
|
| 2017 |
Tedesco D, Grakoui A. Environmental peer pressure: CD4+ T cell help in tolerance and transplantation. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. PMID 28926189 DOI: 10.1002/Lt.24873 |
0.456 |
|
| 2016 |
Seo YJ, Jothikumar P, Suthar MS, Zhu C, Grakoui A. Local Cellular and Cytokine Cues in the Spleen Regulate In Situ T Cell Receptor Affinity, Function, and Fate of CD8(+) T Cells. Immunity. 45: 988-998. PMID 27851926 DOI: 10.1016/J.Immuni.2016.10.024 |
0.508 |
|
| 2016 |
Boisvert M, Zhang W, Elrod EJ, Bernard NF, Villeneuve JP, Bruneau J, Marcotrigiano J, Shoukry NH, Grakoui A. Novel E2 Glycoprotein Tetramer Detects Hepatitis C Virus-Specific Memory B Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 27849172 DOI: 10.4049/Jimmunol.1600763 |
0.545 |
|
| 2016 |
Tedesco D, Thapa M, Gumber S, Elrod EJ, Rahman K, Ibegbu CC, Magliocca JF, Adams AB, Anania F, Grakoui A. CD4+ Foxp3+ T cells promote aberrant IgG production and maintain CD8+ T cell suppression during chronic liver disease. Hepatology (Baltimore, Md.). PMID 27774611 DOI: 10.1002/Hep.28894 |
0.533 |
|
| 2016 |
Moradpour D, Grakoui A, Manns MP. Future landscape of hepatitis C research - Basic, translational and clinical perspectives. Journal of Hepatology. 65: S143-55. PMID 27641984 DOI: 10.1016/J.Jhep.2016.07.026 |
0.491 |
|
| 2016 |
Price AA, Tedesco D, Prasad MR, Workowski KA, Walker CM, Suthar MS, Honegger JR, Grakoui A. Prolonged activation of innate antiviral gene signature after childbirth is determined by IFNL3 genotype. Proceedings of the National Academy of Sciences of the United States of America. PMID 27601663 DOI: 10.1073/Pnas.1602319113 |
0.428 |
|
| 2016 |
Honegger JR, Tedesco D, Kohout JA, Prasad MR, Price AA, Lindquist T, Ohmer S, Moore-Clingenpeel M, Grakoui A, Walker CM. Influence of IFNL3 and HLA-DPB1 genotype on postpartum control of hepatitis C virus replication and T-cell recovery. Proceedings of the National Academy of Sciences of the United States of America. PMID 27601657 DOI: 10.1073/Pnas.1602337113 |
0.54 |
|
| 2016 |
Grakoui A, Crispe IN. Presentation of hepatocellular antigens. Cellular & Molecular Immunology. PMID 26924525 DOI: 10.1038/Cmi.2015.109 |
0.412 |
|
| 2016 |
Price AA, Grakoui A, Weiss DS. Harnessing the Prokaryotic Adaptive Immune System as a Eukaryotic Antiviral Defense. Trends in Microbiology. PMID 26852268 DOI: 10.1016/J.Tim.2016.01.005 |
0.305 |
|
| 2016 |
Zhu C, Jothikumar P, Seo Y, Grakoui A. Anatomic Compartmentalization Regulates TCR-PEP-MHC Interaction and Fate Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.2731 |
0.443 |
|
| 2015 |
Walker CM, Grakoui A. Hepatitis C virus: why do we need a vaccine to prevent a curable persistent infection? Current Opinion in Immunology. 35: 137-43. PMID 26241306 DOI: 10.1016/J.Coi.2015.06.010 |
0.457 |
|
| 2015 |
Price AA, Sampson TR, Ratner HK, Grakoui A, Weiss DS. Cas9-mediated targeting of viral RNA in eukaryotic cells. Proceedings of the National Academy of Sciences of the United States of America. 112: 6164-9. PMID 25918406 DOI: 10.1073/Pnas.1422340112 |
0.332 |
|
| 2015 |
Mimche PN, Brady LM, Bray CF, Lee CM, Thapa M, King TP, Quicke K, McDermott CD, Mimche SM, Grakoui A, Morgan ET, Lamb TJ. The receptor tyrosine kinase EphB2 promotes hepatic fibrosis in mice. Hepatology (Baltimore, Md.). PMID 25784101 DOI: 10.1002/Hep.27792 |
0.35 |
|
| 2015 |
Thapa M, Chinnadurai R, Velazquez VM, Tedesco D, Elrod E, Han JH, Sharma P, Ibegbu C, Gewirtz A, Anania F, Pulendran B, Suthar MS, Grakoui A. Liver fibrosis occurs through dysregulation of MyD88-dependent innate B-cell activity. Hepatology (Baltimore, Md.). 61: 2067-79. PMID 25711908 DOI: 10.1002/Hep.27761 |
0.43 |
|
| 2015 |
Velazquez VM, Uebelhoer LS, Thapa M, Ibegbu CC, Courtney C, Bosinger SE, Magliocca JF, Adams AB, Kirk AD, Knechtle SJ, Kalman D, Suthar MS, Grakoui A. Systems biological analyses reveal the hepatitis C virus (HCV)-specific regulation of hematopoietic development. Hepatology (Baltimore, Md.). 61: 843-56. PMID 25331524 DOI: 10.1002/Hep.27575 |
0.72 |
|
| 2014 |
Price AA, Grakoui A, Honegger JR. HCV adaptations to altered CD8(+) T-cell immunity during pregnancy. Future Virology. 9: 333-336. PMID 25177354 DOI: 10.2217/Fvl.14.15 |
0.601 |
|
| 2014 |
Khan AG, Whidby J, Miller MT, Scarborough H, Zatorski AV, Cygan A, Price AA, Yost SA, Bohannon CD, Jacob J, Grakoui A, Marcotrigiano J. Structure of the core ectodomain of the hepatitis C virus envelope glycoprotein 2. Nature. 509: 381-4. PMID 24553139 DOI: 10.1038/Nature13117 |
0.5 |
|
| 2014 |
Zhao Z, Zhong L, Elrod E, Struble E, Ma L, Yan H, Harman C, Deng L, Virata-Theimer ML, Liu P, Alter H, Grakoui A, Zhang P. A neutralization epitope in the hepatitis C virus E2 glycoprotein interacts with host entry factor CD81. Plos One. 9: e84346. PMID 24400084 DOI: 10.1371/Journal.Pone.0084346 |
0.473 |
|
| 2013 |
Honegger JR, Kim S, Price AA, Kohout JA, McKnight KL, Prasad MR, Lemon SM, Grakoui A, Walker CM. Loss of immune escape mutations during persistent HCV infection in pregnancy enhances replication of vertically transmitted viruses. Nature Medicine. 19: 1529-33. PMID 24162814 DOI: 10.1038/Nm.3351 |
0.541 |
|
| 2013 |
Fuller MJ, Callendret B, Zhu B, Freeman GJ, Hasselschwert DL, Satterfield W, Sharpe AH, Dustin LB, Rice CM, Grakoui A, Ahmed R, Walker CM. Immunotherapy of chronic hepatitis C virus infection with antibodies against programmed cell death-1 (PD-1). Proceedings of the National Academy of Sciences of the United States of America. 110: 15001-6. PMID 23980172 DOI: 10.1073/Pnas.1312772110 |
0.558 |
|
| 2013 |
Norris BA, Uebelhoer LS, Nakaya HI, Price AA, Grakoui A, Pulendran B. Chronic but not acute virus infection induces sustained expansion of myeloid suppressor cell numbers that inhibit viral-specific T cell immunity. Immunity. 38: 309-21. PMID 23438822 DOI: 10.1016/J.Immuni.2012.10.022 |
0.74 |
|
| 2013 |
Dunham RM, Thapa M, Velazquez VM, Elrod EJ, Denning TL, Pulendran B, Grakoui A. Hepatic stellate cells preferentially induce Foxp3+ regulatory T cells by production of retinoic acid. Journal of Immunology (Baltimore, Md. : 1950). 190: 2009-16. PMID 23359509 DOI: 10.4049/Jimmunol.1201937 |
0.528 |
|
| 2012 |
Shin G, Yost SA, Miller MT, Elrod EJ, Grakoui A, Marcotrigiano J. Structural and functional insights into alphavirus polyprotein processing and pathogenesis. Proceedings of the National Academy of Sciences of the United States of America. 109: 16534-9. PMID 23010928 DOI: 10.1073/Pnas.1210418109 |
0.383 |
|
| 2012 |
Velazquez VM, Grakoui A. Immune quiescence and hepatitis B virus: tolerance has its limits. Gastroenterology. 143: 529-32. PMID 22841510 DOI: 10.1053/J.Gastro.2012.07.089 |
0.44 |
|
| 2012 |
Velazquez VM, Hon H, Ibegbu C, Knechtle SJ, Kirk AD, Grakoui A. Hepatic enrichment and activation of myeloid dendritic cells during chronic hepatitis C virus infection. Hepatology (Baltimore, Md.). 56: 2071-81. PMID 22711645 DOI: 10.1002/Hep.25904 |
0.605 |
|
| 2012 |
Chinnadurai R, Velazquez V, Grakoui A. Hepatic Transplant and HCV: A New Playground for an Old Virus American Journal of Transplantation. 12: 298-305. PMID 22044693 DOI: 10.1111/J.1600-6143.2011.03812.X |
0.524 |
|
| 2011 |
Sharma NR, Mateu G, Dreux M, Grakoui A, Cosset FL, Melikyan GB. Hepatitis C virus is primed by CD81 protein for low pH-dependent fusion. The Journal of Biological Chemistry. 286: 30361-76. PMID 21737455 DOI: 10.1074/Jbc.M111.263350 |
0.514 |
|
| 2011 |
Racanelli V, Leone P, Grakoui A. A spatial view of the CD8+ T-cell response: the case of HCV. Reviews in Medical Virology. 21: 347-57. PMID 21732472 DOI: 10.1002/Rmv.702 |
0.602 |
|
| 2010 |
Chinnadurai R, Grakoui A. B7-H4 mediates inhibition of T cell responses by activated murine hepatic stellate cells. Hepatology (Baltimore, Md.). 52: 2177-85. PMID 21064155 DOI: 10.1002/Hep.23953 |
0.441 |
|
| 2010 |
Gupta NA, Mells J, Dunham RM, Grakoui A, Handy J, Saxena NK, Anania FA. Glucagon-like peptide-1 receptor is present on human hepatocytes and has a direct role in decreasing hepatic steatosis in vitro by modulating elements of the insulin signaling pathway. Hepatology (Baltimore, Md.). 51: 1584-92. PMID 20225248 DOI: 10.1002/Hep.23569 |
0.305 |
|
| 2010 |
Radziewicz H, Ibegbu CC, Hon H, Bédard N, Bruneau J, Workowski KA, Knechtle SJ, Kirk AD, Larsen CP, Shoukry NH, Grakoui A. Transient CD86 expression on hepatitis C virus-specific CD8+ T cells in acute infection is linked to sufficient IL-2 signaling. Journal of Immunology (Baltimore, Md. : 1950). 184: 2410-22. PMID 20100932 DOI: 10.4049/Jimmunol.0902994 |
0.587 |
|
| 2009 |
Dionne-Odom J, Osborn MK, Radziewicz H, Grakoui A, Workowski K. Acute hepatitis C and HIV coinfection The Lancet Infectious Diseases. 9: 775-783. PMID 19926037 DOI: 10.1016/S1473-3099(09)70264-6 |
0.39 |
|
| 2009 |
Whidby J, Mateu G, Scarborough H, Demeler B, Grakoui A, Marcotrigiano J. Blocking hepatitis C virus infection with recombinant form of envelope protein 2 ectodomain. Journal of Virology. 83: 11078-89. PMID 19710151 DOI: 10.1128/Jvi.00800-09 |
0.564 |
|
| 2009 |
Berger KL, Cooper JD, Heaton NS, Yoon R, Oakland TE, Jordan TX, Mateu G, Grakoui A, Randall G. Roles for endocytic trafficking and phosphatidylinositol 4-kinase III alpha in hepatitis C virus replication. Proceedings of the National Academy of Sciences of the United States of America. 106: 7577-82. PMID 19376974 DOI: 10.1073/Pnas.0902693106 |
0.475 |
|
| 2009 |
Radziewicz H, Dunham RM, Grakoui A. PD-1 tempers Tregs in chronic HCV infection. The Journal of Clinical Investigation. 119: 450-3. PMID 19306502 DOI: 10.1172/Jci38661 |
0.549 |
|
| 2009 |
Cox AL, Page K, Bruneau J, Shoukry NH, Lauer GM, Kim AY, Rosen HR, Radziewicz H, Grakoui A, Fierer DS, Branch AD, Kaplan DE, Chang KM. Rare birds in North America: acute hepatitis C cohorts. Gastroenterology. 136: 26-31. PMID 19059257 DOI: 10.1053/J.Gastro.2008.11.049 |
0.486 |
|
| 2009 |
Ibegbu CC, Xu YX, Fillos D, Radziewicz H, Grakoui A, Kourtis AP. Differential expression of CD26 on virus-specific CD8(+) T cells during active, latent and resolved infection. Immunology. 126: 346-53. PMID 18657205 DOI: 10.1111/J.1365-2567.2008.02899.X |
0.504 |
|
| 2008 |
Uebelhoer L, Han JH, Callendret B, Mateu G, Shoukry NH, Hanson HL, Rice CM, Walker CM, Grakoui A. Stable cytotoxic T cell escape mutation in hepatitis C virus is linked to maintenance of viral fitness. Plos Pathogens. 4: e1000143. PMID 18773115 DOI: 10.1371/Journal.Ppat.1000143 |
0.752 |
|
| 2008 |
Radziewicz H, Ibegbu CC, Hon H, Osborn MK, Obideen K, Wehbi M, Freeman GJ, Lennox JL, Workowski KA, Hanson HL, Grakoui A. Impaired hepatitis C virus (HCV)-specific effector CD8+ T cells undergo massive apoptosis in the peripheral blood during acute HCV infection and in the liver during the chronic phase of infection. Journal of Virology. 82: 9808-22. PMID 18667503 DOI: 10.1128/Jvi.01075-08 |
0.621 |
|
| 2008 |
Mateu G, Donis RO, Wakita T, Bukh J, Grakoui A. Intragenotypic JFH1 based recombinant hepatitis C virus produces high levels of infectious particles but causes increased cell death. Virology. 376: 397-407. PMID 18455749 DOI: 10.1016/J.Virol.2008.03.027 |
0.519 |
|
| 2008 |
Bowen DG, Shoukry NH, Grakoui A, Fuller MJ, Cawthon AG, Dong C, Hasselschwert DL, Brasky KM, Freeman GJ, Seth NP, Wucherpfennig KW, Houghton M, Walker CM. Variable patterns of programmed death-1 expression on fully functional memory T cells after spontaneous resolution of hepatitis C virus infection. Journal of Virology. 82: 5109-14. PMID 18337576 DOI: 10.1128/Jvi.00060-08 |
0.553 |
|
| 2007 |
Radziewicz H, Uebelhoer L, Bengsch B, Grakoui A. Memory CD8+ T cell differentiation in viral infection: a cell for all seasons. World Journal of Gastroenterology. 13: 4848-57. PMID 17828816 DOI: 10.3748/Wjg.V13.I36.4848 |
0.767 |
|
| 2007 |
McMullan LK, Grakoui A, Evans MJ, Mihalik K, Puig M, Branch AD, Feinstone SM, Rice CM. Evidence for a functional RNA element in the hepatitis C virus core gene. Proceedings of the National Academy of Sciences of the United States of America. 104: 2879-84. PMID 17299041 DOI: 10.1073/Pnas.0611267104 |
0.511 |
|
| 2007 |
Radziewicz H, Ibegbu CC, Fernandez ML, Workowski KA, Obideen K, Wehbi M, Hanson HL, Steinberg JP, Masopust D, Wherry EJ, Altman JD, Rouse BT, Freeman GJ, Ahmed R, Grakoui A. Liver-infiltrating lymphocytes in chronic human hepatitis C virus infection display an exhausted phenotype with high levels of PD-1 and low levels of CD127 expression. Journal of Virology. 81: 2545-53. PMID 17182670 DOI: 10.1128/Jvi.02021-06 |
0.588 |
|
| 2006 |
Marcello T, Grakoui A, Barba-Spaeth G, Machlin ES, Kotenko SV, MacDonald MR, Rice CM. Interferons alpha and lambda inhibit hepatitis C virus replication with distinct signal transduction and gene regulation kinetics. Gastroenterology. 131: 1887-98. PMID 17087946 DOI: 10.1053/J.Gastro.2006.09.052 |
0.43 |
|
| 2006 |
Grakoui A, John Wherry E, Hanson HL, Walker C, Ahmed R. Turning on the off switch: regulation of anti-viral T cell responses in the liver by the PD-1/PD-L1 pathway. Journal of Hepatology. 45: 468-72. PMID 16901572 DOI: 10.1016/J.Jhep.2006.07.009 |
0.575 |
|
| 2004 |
Larsson M, Babcock E, Grakoui A, Shoukry N, Lauer G, Rice C, Walker C, Bhardwaj N. Lack of phenotypic and functional impairment in dendritic cells from chimpanzees chronically infected with hepatitis C virus. Journal of Virology. 78: 6151-61. PMID 15163708 DOI: 10.1128/Jvi.78.12.6151-6161.2004 |
0.517 |
|
| 2003 |
Woollard DJ, Grakoui A, Shoukry NH, Murthy KK, Campbell KJ, Walker CM. Characterization of HCV-specific Patr class II restricted CD4+ T cell responses in an acutely infected chimpanzee. Hepatology (Baltimore, Md.). 38: 1297-306. PMID 14578870 DOI: 10.1053/jhep.2003.50478 |
0.562 |
|
| 2003 |
Grakoui A, Shoukry NH, Woollard DJ, Han JH, Hanson HL, Ghrayeb J, Murthy KK, Rice CM, Walker CM. HCV persistence and immune evasion in the absence of memory T cell help. Science (New York, N.Y.). 302: 659-62. PMID 14576438 DOI: 10.1126/Science.1088774 |
0.5 |
|
| 2003 |
Shoukry NH, Grakoui A, Houghton M, Chien DY, Ghrayeb J, Reimann KA, Walker CM. Memory CD8+ T cells are required for protection from persistent hepatitis C virus infection. The Journal of Experimental Medicine. 197: 1645-55. PMID 12810686 DOI: 10.1084/Jem.20030239 |
0.552 |
|
| 2003 |
Randall G, Grakoui A, Rice CM. Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAs. Proceedings of the National Academy of Sciences of the United States of America. 100: 235-40. PMID 12518066 DOI: 10.1073/Pnas.0235524100 |
0.445 |
|
| 1995 |
Koziel MJ, Dudley D, Afdhal N, Grakoui A, Rice CM, Choo QL, Houghton M, Walker BD. HLA class I-restricted cytotoxic T lymphocytes specific for hepatitis C virus: Identification of multiple epitopes and characterization of patterns of cytokine release Journal of Clinical Investigation. 96: 2311-2321. PMID 7593618 DOI: 10.1172/Jci118287 |
0.513 |
|
| 1989 |
Hahn YS, Grakoui A, Rice CM, Strauss EG, Strauss JH. Mapping of RNA- temperature-sensitive mutants of Sindbis virus: Complementation group F mutants have lesions in nsP4 Journal of Virology. 63: 1194-1202. PMID 2521674 DOI: 10.1128/Jvi.63.3.1194-1202.1989 |
0.345 |
|
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