Pearlly S. Yan - Publications

Affiliations: 
Human Cancer Genetics Program Ohio State University, Columbus, Columbus, OH 

116 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Singh K, Rustagi Y, Abouhashem AS, Tabasum S, Verma P, Hernandez E, Pal D, Khona DK, Mohanty SK, Kumar M, Srivastava R, Guda PR, Verma SS, Mahajan S, Killian JA, ... ... Yan P, et al. Genome-wide DNA hypermethylation opposes healing in chronic wound patients by impairing epithelial-to-mesenchymal transition. The Journal of Clinical Investigation. PMID 35819852 DOI: 10.1172/JCI157279  0.313
2020 Xia X, Wu WKK, Wong SH, Liu D, Kwong TNY, Nakatsu G, Yan PS, Chuang YM, Chan MW, Coker OO, Chen Z, Yeoh YK, Zhao L, Wang X, Cheng WY, et al. Bacteria pathogens drive host colonic epithelial cell promoter hypermethylation of tumor suppressor genes in colorectal cancer. Microbiome. 8: 108. PMID 32678024 DOI: 10.1186/S40168-020-00847-4  0.407
2020 Denninger JK, Chen X, Turkoglu AM, Sarchet P, Volk AR, Rieskamp JD, Yan P, Kirby ED. Defining the adult hippocampal neural stem cell secretome: in vivo versus in vitro transcriptomic differences and their correlation to secreted protein levels. Brain Research. 146717. PMID 32035887 DOI: 10.1016/J.Brainres.2020.146717  0.316
2019 Chen LY, Huang RL, Chan MWY, Yan PS, Huang TS, Wu RC, Suryo Rahmanto Y, Su PH, Weng YC, Chou JL, Chao TK, Wang YC, Shih IM, Lai HC. TET1 reprograms the epithelial ovarian cancer epigenome and reveals casein kinase 2α as a therapeutic target. The Journal of Pathology. PMID 30883733 DOI: 10.1002/Path.5266  0.391
2019 Caution K, Pan A, Krause K, Badr A, Hamilton K, Vaidya A, Gosu H, Daily K, Estfanous S, Gavrilin MA, Drew ME, Cormet-Boyaka E, Chen X, Frankhouser DE, Bundschuh R, ... Yan P, et al. Methylomic correlates of autophagy activity in cystic fibrosis. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. PMID 30737168 DOI: 10.1016/J.Jcf.2019.01.011  0.317
2019 Chuang YM, Hung S, Chou JL, Huang W, Yan PS, Liu T, Chan MWY. Abstract 4326: Epigenetic control of chromosome instability by STAT3 in gastric cancer Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-4326  0.303
2019 Frankhouser DE, Woelke S, Sovic M, Bundschuh R, Yan P, Yee LD. Abstract 4222: Omega-3 fatty acids produce DNA methylation changes in inflammation-related genes and pathways with implication of toll-like receptor signaling Cancer Research. 79: 4222-4222. DOI: 10.1158/1538-7445.Am2019-4222  0.425
2018 Polusani SR, Huang YW, Huang G, Chen CW, Wang CM, Lin LL, Osmulski P, Lucio ND, Liu L, Hsu YT, Zhou Y, Lin CL, Aguilera-Barrantes I, Valente PT, Kost ER, ... ... Yan P, et al. Adipokines Deregulate Cellular Communication via Epigenetic Repression of Gap Junction Loci in Obese Endometrial Cancer. Cancer Research. PMID 30389702 DOI: 10.1158/0008-5472.Can-18-1615  0.403
2018 Chen Z, Wu D, Thomas-Ahner JM, Lu C, Zhao P, Zhang Q, Geraghty C, Yan PS, Hankey W, Sunkel B, Cheng X, Antonarakis ES, Wang QE, Liu Z, Huang TH, et al. Diverse AR-V7 cistromes in castration-resistant prostate cancer are governed by HoxB13. Proceedings of the National Academy of Sciences of the United States of America. PMID 29844167 DOI: 10.1073/Pnas.1718811115  0.303
2018 Killian JA, Topiwala TM, Pelletier AR, Frankhouser DE, Yan PS, Bundschuh R. FuSpot: a web-based tool for visual evaluation of fusion candidates. Bmc Genomics. 19: 139. PMID 29439649 DOI: 10.1186/S12864-018-4486-3  0.324
2017 Trimarchi MP, Yan P, Groden J, Bundschuh R, Goodfellow PJ. Identification of endometrial cancer methylation features using combined methylation analysis methods. Plos One. 12: e0173242. PMID 28278225 DOI: 10.1371/Journal.Pone.0173242  0.476
2017 Goswami S, Mani R, Mo X, Yan PS, Broe MB, Bundschuh R, Beaver LS, Zapolnik K, Xie Z, Bucci D, Lucas DM, Walker AR, Mims AS, Klisovic RB, Chen C, et al. OSU-2S, a Novel PKC Activator, Mediates PKC Dependent Cell Death, Differentiation and Cell Cycle Arrest in Acute Myeloid Leukemia Blood. 130: 1247-1247. DOI: 10.1182/Blood.V130.Suppl_1.1247.1247  0.313
2016 Moreland B, Oman K, Curfman J, Yan P, Bundschuh R. Methyl-CpG/MBD2 Interaction Requires Minimum Separation and Exhibits Minimal Sequence Specificity. Biophysical Journal. 111: 2551-2561. PMID 28002732 DOI: 10.1016/J.Bpj.2016.11.014  0.422
2016 Stiff A, Caserta E, Sborov DW, Nuovo GJ, Mo X, Schlotter SY, Canella A, Smith E, Badway J, Old M, Jaime-Ramirez AC, Yan P, Benson DM, Byrd JC, Baiocchi R, et al. Histone Deacetylase Inhibitors Enhance the Therapeutic Potential of Reovirus in Multiple Myeloma. Molecular Cancer Therapeutics. PMID 26809490 DOI: 10.1158/1535-7163.Mct-15-0240-T  0.353
2016 Hahn NM, Cramer HM, Badve SS, Cheng L, Gokmen-Polar Y, Miller DF, Buechlein A, Rusch DB, Fang F, Frankhouser D, Bundschu R, Javkhlan-Ochir G, Koch MO, Bihrle R, Foster R, ... ... Yan P, et al. Identification of novel immunomodulatory tumor biology through comprehensive characterization of a metastases-specific epigenome in patients with metachronous primary and metastatic urothelial carcinoma (UC) tumor pairs. Journal of Clinical Oncology. 34: 452-452. DOI: 10.1200/Jco.2016.34.2_Suppl.452  0.409
2016 Rizzotto L, Bottoni A, Lai T, Liu C, Yan PS, Ozer HG, Lapalombella R, Woyach JA, Oakes CC, Blachly JS, Sampath D. Role of Histone Deacetylase-Mediated Gene Silencing in Chronic Lymphocytic Leukemia Progression Blood. 128: 2705-2705. DOI: 10.1182/Blood.V128.22.2705.2705  0.371
2016 Yee LD, Lester JL, Straka SR, Woelke S, Ke J, Shen R, Yan P, Zhang J, Belury MA, Clinton SK. Abstract CT086: Omega-3 fatty acids and ERPR(-) and HER-2/neu(+) breast cancer prevention Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Ct086  0.338
2016 Lin JMj, Chou J, Frankhouser DE, Chuang Y, Chang AL, Zeng L, Chen S, Lin R, Wu C, Wei K, Ng EKW, Yan PS, Cheng ASL, Li C, Chan MWY. Abstract 1501: Aberrant JAK/STAT signaling orchestrates global promoter methylation and promotes TGF-β mediated EMT through epigenetic silencing of miR-193a in gastric cancer Cancer Research. 76: 1501-1501. DOI: 10.1158/1538-7445.Am2016-1501  0.392
2015 Tseng YC, Kulp SK, Lai IL, Hsu EC, He WA, Frankhouser DE, Yan PS, Mo X, Bloomston M, Lesinski GB, Marcucci G, Guttridge DC, Bekaii-Saab T, Chen CS. Preclinical Investigation of the Novel Histone Deacetylase Inhibitor AR-42 in the Treatment of Cancer-Induced Cachexia. Journal of the National Cancer Institute. 107. PMID 26464423 DOI: 10.1093/Jnci/Djv274  0.333
2015 Ayyala DN, Frankhouser DE, Ganbat JO, Marcucci G, Bundschuh R, Yan P, Lin S. Statistical Methods for Detecting Differentially Methylated Regions Based on MethylCap-Seq Data. Briefings in Bioinformatics. PMID 26454095 DOI: 10.1093/Bib/Bbv089  0.431
2015 Koo GB, Morgan MJ, Lee DG, Kim WJ, Yoon JH, Koo JS, Kim SI, Kim SJ, Son MK, Hong SS, Levy JM, Pollyea DA, Jordan CT, Yan P, Frankhouser D, et al. Methylation-dependent loss of RIP3 expression in cancer represses programmed necrosis in response to chemotherapeutics. Cell Research. 25: 707-25. PMID 25952668 DOI: 10.1038/Cr.2015.56  0.41
2015 Chou JL, Huang RL, Shay J, Chen LY, Lin SJ, Yan PS, Chao WT, Lai YH, Lai YL, Chao TK, Lee CI, Tai CK, Wu SF, Nephew KP, Huang TH, et al. Hypermethylation of the TGF-β target, ABCA1 is associated with poor prognosis in ovarian cancer patients. Clinical Epigenetics. 7: 1. PMID 25628764 DOI: 10.1186/S13148-014-0036-2  0.39
2015 Chen Z, Lan X, Thomas-Ahner JM, Wu D, Liu X, Ye Z, Wang L, Sunkel B, Grenade C, Chen J, Zynger DL, Yan PS, Huang J, Nephew KP, Huang TH, et al. Agonist and antagonist switch DNA motifs recognized by human androgen receptor in prostate cancer. The Embo Journal. 34: 502-16. PMID 25535248 DOI: 10.15252/Embj.201490306  0.324
2015 Niederwieser C, Kohlschmidt J, Volinia S, Whitman SP, Metzeler KH, Eisfeld AK, Maharry K, Yan P, Frankhouser D, Becker H, Schwind S, Carroll AJ, Nicolet D, Mendler JH, Curfman JP, et al. Prognostic and biologic significance of DNMT3B expression in older patients with cytogenetically normal primary acute myeloid leukemia. Leukemia. 29: 567-75. PMID 25204569 DOI: 10.1038/Leu.2014.267  0.37
2015 Meng W, Lautenschlaeger T, Frankhouser D, Ye Z, Huebner A, Jin V, Yan P, Chakravarti A. Abstract 2963: 5-hydroxymethylcytosine alterations at H3K9me3 marked genomic regions serve as potential biomarker for renal cell carcinoma patients Cancer Research. 75: 2963-2963. DOI: 10.1158/1538-7445.Am2015-2963  0.35
2015 Chen L, Huang R, Yan PS, Huang T, Liao Y, Chou J, Lin JMJ, Chao T, Chan MWY, Chang WW, Lai H. Abstract 1128: TET1-mediated epigenetic reprogramming switches metabolism and promotes malignant phenotypes of ovarian cancer Cancer Research. 75: 1128-1128. DOI: 10.1158/1538-7445.Am2015-1128  0.45
2014 Garzon R, Volinia S, Papaioannou D, Nicolet D, Kohlschmidt J, Yan PS, Mrózek K, Bucci D, Carroll AJ, Baer MR, Wetzler M, Carter TH, Powell BL, Kolitz JE, Moore JO, et al. Expression and prognostic impact of lncRNAs in acute myeloid leukemia. Proceedings of the National Academy of Sciences of the United States of America. 111: 18679-84. PMID 25512507 DOI: 10.1073/Pnas.1422050112  0.315
2014 Frankhouser DE, Murphy M, Blachly JS, Park J, Zoller MW, Ganbat JO, Curfman J, Byrd JC, Lin S, Marcucci G, Yan P, Bundschuh R. PrEMeR-CG: inferring nucleotide level DNA methylation values from MethylCap-seq data. Bioinformatics (Oxford, England). 30: 3567-74. PMID 25178460 DOI: 10.1093/Bioinformatics/Btu583  0.421
2014 Marcucci G, Yan P, Maharry K, Frankhouser D, Nicolet D, Metzeler KH, Kohlschmidt J, Mrózek K, Wu YZ, Bucci D, Curfman JP, Whitman SP, Eisfeld AK, Mendler JH, Schwind S, et al. Epigenetics meets genetics in acute myeloid leukemia: clinical impact of a novel seven-gene score. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 32: 548-56. PMID 24378410 DOI: 10.1200/Jco.2013.50.6337  0.375
2014 Tseng Y, Kulp S, Lai I, He W, Bundschuh R, Frankhouser D, Yan P, Guttridge D, Marcucci G, Chen C, Bekaii-Saab T. Abstract 5540: Preclinical investigation of the novel histone deacetylase (HDAC) inhibitor AR-42 in the treatment of cancer-induced cachexia Cancer Research. 74: 5540-5540. DOI: 10.1158/1538-7445.Am2014-5540  0.355
2014 Lin JM, Shay J, Chou J, Yan PS, Huang TH-, Lai HC, Chan MWy. Abstract 2318: The role of EZH2 as an epigenetic switch of the TGF-β/SMAD4 targets in regulating EMT in ovarian cancer Cancer Research. 74: 2318-2318. DOI: 10.1158/1538-7445.Am2014-2318  0.408
2013 Hsu PY, Hsu HK, Lan X, Juan L, Yan PS, Labanowska J, Heerema N, Hsiao TH, Chiu YC, Chen Y, Liu Y, Li L, Li R, Thompson IM, Nephew KP, et al. Amplification of distant estrogen response elements deregulates target genes associated with tamoxifen resistance in breast cancer. Cancer Cell. 24: 197-212. PMID 23948299 DOI: 10.1016/J.Ccr.2013.07.007  0.396
2013 Rhee JK, Kim K, Chae H, Evans J, Yan P, Zhang BT, Gray J, Spellman P, Huang TH, Nephew KP, Kim S. Integrated analysis of genome-wide DNA methylation and gene expression profiles in molecular subtypes of breast cancer. Nucleic Acids Research. 41: 8464-74. PMID 23887935 DOI: 10.1093/Nar/Gkt643  0.493
2013 Dakhlallah D, Batte K, Wang Y, Cantemir-Stone CZ, Yan P, Nuovo G, Mikhail A, Hitchcock CL, Wright VP, Nana-Sinkam SP, Piper MG, Marsh CB. Epigenetic regulation of miR-17~92 contributes to the pathogenesis of pulmonary fibrosis. American Journal of Respiratory and Critical Care Medicine. 187: 397-405. PMID 23306545 DOI: 10.1164/Rccm.201205-0888Oc  0.317
2013 Rao X, Evans J, Chae H, Pilrose J, Kim S, Yan P, Huang RL, Lai HC, Lin H, Liu Y, Miller D, Rhee JK, Huang YW, Gu F, Gray JW, et al. CpG island shore methylation regulates caveolin-1 expression in breast cancer. Oncogene. 32: 4519-28. PMID 23128390 DOI: 10.1038/Onc.2012.474  0.439
2013 Trimarchi MP, Yan PS, Huang K, Groden J, Bundschuh R, Goodfellow PJ. Abstract B41: Methylome profiling identifies unique patterns of DNA methylation in endometrial cancers Cancer Research. 73. DOI: 10.1158/1538-7445.Cec13-B41  0.51
2013 Bernot KM, Nemer JS, Santhanam R, Liu S, Marcucci GG, Zorko NA, Whitman SP, Yan P, Frankhouser D, Bundschuh R, Zhang M, Siebenaler RF, Ahmed EH, McConnell KK, Munoz M, et al. Abstract 3249: Targeting the miR29b/Sp1/Dnmt pathway for curative therapy in Mll-PTD/Flt3-ITD acute myeloid leukemia. Cancer Research. 73: 3249-3249. DOI: 10.1158/1538-7445.Am2013-3249  0.345
2012 Trimarchi MP, Murphy M, Frankhouser D, Rodriguez BA, Curfman J, Marcucci G, Yan P, Bundschuh R. Enrichment-based DNA methylation analysis using next-generation sequencing: sample exclusion, estimating changes in global methylation, and the contribution of replicate lanes. Bmc Genomics. 13: S6. PMID 23281662 DOI: 10.1186/1471-2164-13-S8-S6  0.442
2012 Villar D, Ortiz-Barahona A, Gómez-Maldonado L, Pescador N, Sánchez-Cabo F, Hackl H, Rodriguez BA, Trajanoski Z, Dopazo A, Huang TH, Yan PS, Del Peso L. Cooperativity of stress-responsive transcription factors in core hypoxia-inducible factor binding regions. Plos One. 7: e45708. PMID 23029193 DOI: 10.1371/Journal.Pone.0045708  0.311
2012 von dem Knesebeck A, Felsberg J, Waha A, Hartmann W, Scheffler B, Glas M, Hammes J, Mikeska T, Yan PS, Endl E, Simon M, Reifenberger G, Pietsch T, Waha A. RANK (TNFRSF11A) is epigenetically inactivated and induces apoptosis in gliomas. Neoplasia (New York, N.Y.). 14: 526-34. PMID 22787434 DOI: 10.1596/Neo.12360  0.429
2012 Yan P, Frankhouser D, Murphy M, Tam HH, Rodriguez B, Curfman J, Trimarchi M, Geyer S, Wu YZ, Whitman SP, Metzeler K, Walker A, Klisovic R, Jacob S, Grever MR, et al. Genome-wide methylation profiling in decitabine-treated patients with acute myeloid leukemia. Blood. 120: 2466-74. PMID 22786882 DOI: 10.1182/Blood-2012-05-429175  0.411
2012 Palamarchuk A, Yan PS, Zanesi N, Wang L, Rodrigues B, Murphy M, Balatti V, Bottoni A, Nazaryan N, Alder H, Rassenti L, Kipps TJ, Freitas M, Croce CM, Pekarsky Y. Tcl1 protein functions as an inhibitor of de novo DNA methylation in B-cell chronic lymphocytic leukemia (CLL). Proceedings of the National Academy of Sciences of the United States of America. 109: 2555-60. PMID 22308499 DOI: 10.1073/Pnas.1200003109  0.39
2012 Miller DF, Lui Y, Yan P, Rodriguez B, Lin H, Goel S, Jani E, Bhattrai A, Koekesh K, Guo C, Huang TH, Nephew KP. Abstract 4188: Whole transcriptome analyses of platinum-resistant ovarian cancer cells Cancer Research. 72: 4188-4188. DOI: 10.1158/1538-7445.Am2012-4188  0.438
2011 Sun S, Huang YW, Yan PS, Huang TH, Lin S. Preprocessing differential methylation hybridization microarray data. Biodata Mining. 4: 13. PMID 21575229 DOI: 10.1186/1756-0381-4-13  0.42
2011 Shen C, Huang Y, Liu Y, Wang G, Zhao Y, Wang Z, Teng M, Wang Y, Flockhart DA, Skaar TC, Yan P, Nephew KP, Huang TH, Li L. A modulated empirical Bayes model for identifying topological and temporal estrogen receptor α regulatory networks in breast cancer. Bmc Systems Biology. 5: 67. PMID 21554733 DOI: 10.1186/1752-0509-5-67  0.384
2011 Yeh KT, Chen TH, Yang HW, Chou JL, Chen LY, Yeh CM, Chen YH, Lin RI, Su HY, Chen GC, Deatherage DE, Huang YW, Yan PS, Lin HJ, Nephew KP, et al. Aberrant TGFβ/SMAD4 signaling contributes to epigenetic silencing of a putative tumor suppressor, RunX1T1 in ovarian cancer. Epigenetics : Official Journal of the Dna Methylation Society. 6: 727-39. PMID 21540640 DOI: 10.4161/Epi.6.6.15856  0.482
2011 Sun S, Chen Z, Yan PS, Huang YW, Huang TH, Lin S. Identifying hypermethylated CpG islands using a quantile regression model. Bmc Bioinformatics. 12: 54. PMID 21324121 DOI: 10.1186/1471-2105-12-54  0.47
2011 Rodriguez BA, Weng YI, Liu TM, Zuo T, Hsu PY, Lin CH, Cheng AL, Cui H, Yan PS, Huang TH. Estrogen-mediated epigenetic repression of the imprinted gene cyclin-dependent kinase inhibitor 1C in breast cancer cells. Carcinogenesis. 32: 812-21. PMID 21304052 DOI: 10.1093/Carcin/Bgr017  0.473
2011 Hsu CC, Leu YW, Tseng MJ, Lee KD, Kuo TY, Yen JY, Lai YL, Hung YC, Sun WS, Chen CM, Chu PY, Yeh KT, Yan PS, Chang YS, Huang TH, et al. Functional characterization of Trip10 in cancer cell growth and survival. Journal of Biomedical Science. 18: 12. PMID 21299869 DOI: 10.1186/1423-0127-18-12  0.472
2011 van Roon EH, de Miranda NF, van Nieuwenhuizen MP, de Meijer EJ, van Puijenbroek M, Yan PS, Huang TH, van Wezel T, Morreau H, Boer JM. Tumour-specific methylation of PTPRG intron 1 locus in sporadic and Lynch syndrome colorectal cancer. European Journal of Human Genetics : Ejhg. 19: 307-12. PMID 21150880 DOI: 10.1038/Ejhg.2010.187  0.479
2011 Chou J, Chen L, Su H, Lin S, Huang Y, Deatherage DE, Yan PS, Nephew KP, Lee C, Huang TH-, Lai H, Chan MWY. Abstract 83: Hypomethylation of TGF-beta target gene,ABCA1in ovarian cancer and cancer initialing cell and is associated with poor prognosis in cancer patients Cancer Research. 71: 83-83. DOI: 10.1158/1538-7445.Am2011-83  0.449
2010 Hsiao SH, Lee KD, Hsu CC, Tseng MJ, Jin VX, Sun WS, Hung YC, Yeh KT, Yan PS, Lai YY, Sun HS, Lu YJ, Chang YS, Tsai SJ, Huang TH, et al. DNA methylation of the Trip10 promoter accelerates mesenchymal stem cell lineage determination. Biochemical and Biophysical Research Communications. 400: 305-12. PMID 20727853 DOI: 10.1016/J.Bbrc.2010.08.048  0.459
2010 Ghoshal K, Motiwala T, Claus R, Yan P, Kutay H, Datta J, Majumder S, Bai S, Majumder A, Huang T, Plass C, Jacob ST. HOXB13, a target of DNMT3B, is methylated at an upstream CpG island, and functions as a tumor suppressor in primary colorectal tumors. Plos One. 5: e10338. PMID 20454457 DOI: 10.1371/Journal.Pone.0010338  0.446
2010 Hsu PY, Hsu HK, Singer GA, Yan PS, Rodriguez BA, Liu JC, Weng YI, Deatherage DE, Chen Z, Pereira JS, Lopez R, Russo J, Wang Q, Lamartiniere CA, Nephew KP, et al. Estrogen-mediated epigenetic repression of large chromosomal regions through DNA looping. Genome Research. 20: 733-44. PMID 20442245 DOI: 10.1101/Gr.101923.109  0.442
2010 Waha A, Felsberg J, Hartmann W, von dem Knesebeck A, Mikeska T, Joos S, Wolter M, Koch A, Yan PS, Endl E, Wiestler OD, Reifenberger G, Pietsch T, Waha A. Epigenetic downregulation of mitogen-activated protein kinase phosphatase MKP-2 relieves its growth suppressive activity in glioma cells. Cancer Research. 70: 1689-99. PMID 20124482 DOI: 10.1158/0008-5472.Can-09-3218  0.411
2010 Chou JL, Su HY, Chen LY, Liao YP, Hartman-Frey C, Lai YH, Yang HW, Deatherage DE, Kuo CT, Huang YW, Yan PS, Hsiao SH, Tai CK, Lin HJ, Davuluri RV, et al. Promoter hypermethylation of FBXO32, a novel TGF-beta/SMAD4 target gene and tumor suppressor, is associated with poor prognosis in human ovarian cancer. Laboratory Investigation; a Journal of Technical Methods and Pathology. 90: 414-25. PMID 20065949 DOI: 10.1038/Labinvest.2009.138  0.439
2010 Chou J, Su H, Chen L, Liao Y, Hartman-Frey C, Lai Y, Yang H, Deatherage DE, Kuo C, Huang Y, Yan PS, Hsiao S, Tai C, Lin HL, Davuluri RV, et al. Abstract 3072: Promoter hypermethylation of FBXO32, a novel TGF-β/SMAD4 target gene and tumor suppressor, is associated with poor prognosis in human ovarian cancer Cancer Research. 70: 3072-3072. DOI: 10.1158/1538-7445.Am10-3072  0.42
2009 Sun S, Yan PS, Huang TH, Lin S. Identifying differentially methylated genes using mixed effect and generalized least square models. Bmc Bioinformatics. 10: 404. PMID 20003206 DOI: 10.1186/1471-2105-10-404  0.469
2009 Weng YI, Huang TH, Yan PS. Methylated DNA immunoprecipitation and microarray-based analysis: detection of DNA methylation in breast cancer cell lines. Methods in Molecular Biology (Clifton, N.J.). 590: 165-76. PMID 19763503 DOI: 10.1007/978-1-60327-378-7_10  0.45
2009 Huang YW, Jansen RA, Fabbri E, Potter D, Liyanarachchi S, Chan MW, Liu JC, Crijns AP, Brown R, Nephew KP, van der Zee AG, Cohn DE, Yan PS, Huang TH, Lin HJ. Identification of candidate epigenetic biomarkers for ovarian cancer detection. Oncology Reports. 22: 853-61. PMID 19724865 DOI: 10.3892/Or_00000509  0.42
2009 Taslim C, Wu J, Yan P, Singer G, Parvin J, Huang T, Lin S, Huang K. Comparative study on ChIP-seq data: normalization and binding pattern characterization. Bioinformatics (Oxford, England). 25: 2334-40. PMID 19561022 DOI: 10.1093/Bioinformatics/Btp384  0.309
2009 Li M, Balch C, Montgomery JS, Jeong M, Chung JH, Yan P, Huang TH, Kim S, Nephew KP. Integrated analysis of DNA methylation and gene expression reveals specific signaling pathways associated with platinum resistance in ovarian cancer. Bmc Medical Genomics. 2: 34. PMID 19505326 DOI: 10.1186/1755-8794-2-34  0.441
2009 Deatherage DE, Potter D, Yan PS, Huang TH, Lin S. Methylation analysis by microarray. Methods in Molecular Biology (Clifton, N.J.). 556: 117-39. PMID 19488875 DOI: 10.1007/978-1-60327-192-9_9  0.417
2009 Yan PS, Potter D, Deatherage DE, Huang TH, Lin S. Differential methylation hybridization: profiling DNA methylation with a high-density CpG island microarray. Methods in Molecular Biology (Clifton, N.J.). 507: 89-106. PMID 18987809 DOI: 10.1007/978-1-59745-522-0_8  0.424
2008 Estécio MR, Yan PS, Huang TH, Issa JP. Methylated CpG Island Amplification and Microarray (MCAM) for High-Throughput Analysis of DNA Methylation. Csh Protocols. 2008: pdb.prot4974. PMID 21356790 DOI: 10.1101/Pdb.Prot4974  0.445
2008 Lin HJ, Zuo T, Lin CH, Kuo CT, Liyanarachchi S, Sun S, Shen R, Deatherage DE, Potter D, Asamoto L, Lin S, Yan PS, Cheng AL, Ostrowski MC, Huang TH. Breast cancer-associated fibroblasts confer AKT1-mediated epigenetic silencing of Cystatin M in epithelial cells. Cancer Research. 68: 10257-66. PMID 19074894 DOI: 10.1158/0008-5472.Can-08-0288  0.463
2008 Potter DP, Yan P, Huang TH, Lin S. Probe signal correction for differential methylation hybridization experiments. Bmc Bioinformatics. 9: 453. PMID 18947421 DOI: 10.1186/1471-2105-9-453  0.303
2008 Zhang Y, Liu T, Yan P, Huang T, Dewille J. Identification and characterization of CCAAT/Enhancer Binding proteindelta (C/EBPdelta) target genes in G0 growth arrested mammary epithelial cells. Bmc Molecular Biology. 9: 83. PMID 18828910 DOI: 10.1186/1471-2199-9-83  0.324
2008 Chan MW, Huang YW, Hartman-Frey C, Kuo CT, Deatherage D, Qin H, Cheng AS, Yan PS, Davuluri RV, Huang TH, Nephew KP, Lin HJ. Aberrant transforming growth factor beta1 signaling and SMAD4 nuclear translocation confer epigenetic repression of ADAM19 in ovarian cancer. Neoplasia (New York, N.Y.). 10: 908-19. PMID 18714391 DOI: 10.1593/Neo.08540  0.338
2008 Dai W, Teodoridis JM, Graham J, Zeller C, Huang TH, Yan P, Vass JK, Brown R, Paul J. Methylation Linear Discriminant Analysis (MLDA) for identifying differentially methylated CpG islands. Bmc Bioinformatics. 9: 337. PMID 18691414 DOI: 10.1186/1471-2105-9-337  0.455
2008 Singer GA, Wu J, Yan P, Plass C, Huang TH, Davuluri RV. Genome-wide analysis of alternative promoters of human genes using a custom promoter tiling array. Bmc Genomics. 9: 349. PMID 18655706 DOI: 10.1186/1471-2164-9-349  0.367
2008 Wang LS, Huang YW, Liu S, Yan P, Lin YC. Conjugated linoleic acid induces apoptosis through estrogen receptor alpha in human breast tissue. Bmc Cancer. 8: 208. PMID 18652667 DOI: 10.1186/1471-2407-8-208  0.322
2008 Zhang S, Balch C, Chan MW, Lai HC, Matei D, Schilder JM, Yan PS, Huang TH, Nephew KP. Identification and characterization of ovarian cancer-initiating cells from primary human tumors. Cancer Research. 68: 4311-20. PMID 18519691 DOI: 10.1158/0008-5472.Can-08-0364  0.326
2008 Rodriguez BA, Cheng AS, Yan PS, Potter D, Agosto-Perez FJ, Shapiro CL, Huang TH. Epigenetic repression of the estrogen-regulated Homeobox B13 gene in breast cancer. Carcinogenesis. 29: 1459-65. PMID 18499701 DOI: 10.1093/Carcin/Bgn115  0.427
2008 Lai HC, Lin YW, Huang TH, Yan P, Huang RL, Wang HC, Liu J, Chan MW, Chu TY, Sun CA, Chang CC, Yu MH. Identification of novel DNA methylation markers in cervical cancer. International Journal of Cancer. Journal International Du Cancer. 123: 161-7. PMID 18398837 DOI: 10.1002/Ijc.23519  0.434
2008 Cheng AS, Culhane AC, Chan MW, Venkataramu CR, Ehrich M, Nasir A, Rodriguez BA, Liu J, Yan PS, Quackenbush J, Nephew KP, Yeatman TJ, Huang TH. Epithelial progeny of estrogen-exposed breast progenitor cells display a cancer-like methylome. Cancer Research. 68: 1786-96. PMID 18339859 DOI: 10.1158/0008-5472.Can-07-5547  0.382
2007 Estécio MR, Yan PS, Ibrahim AE, Tellez CS, Shen L, Huang TH, Issa JP. High-throughput methylation profiling by MCA coupled to CpG island microarray. Genome Research. 17: 1529-36. PMID 17785535 DOI: 10.1101/Gr.6417007  0.478
2007 Zighelboim I, Goodfellow PJ, Schmidt AP, Walls KC, Mallon MA, Mutch DG, Yan PS, Huang TH, Powell MA. Differential methylation hybridization array of endometrial cancers reveals two novel cancer-specific methylation markers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 2882-9. PMID 17504987 DOI: 10.1158/1078-0432.Ccr-06-2367  0.452
2007 Estécio MR, Gharibyan V, Shen L, Ibrahim AE, Doshi K, He R, Jelinek J, Yang AS, Yan PS, Huang TH, Tajara EH, Issa JP. LINE-1 hypomethylation in cancer is highly variable and inversely correlated with microsatellite instability. Plos One. 2: e399. PMID 17476321 DOI: 10.1371/Journal.Pone.0000399  0.46
2007 Wang Z, Yan P, Potter D, Eng C, Huang TH, Lin S. Heritable clustering and pathway discovery in breast cancer integrating epigenetic and phenotypic data. Bmc Bioinformatics. 8: 38. PMID 17270052 DOI: 10.1186/1471-2105-8-38  0.356
2006 Fan M, Yan PS, Hartman-Frey C, Chen L, Paik H, Oyer SL, Salisbury JD, Cheng AS, Li L, Abbosh PH, Huang TH, Nephew KP. Diverse gene expression and DNA methylation profiles correlate with differential adaptation of breast cancer cells to the antiestrogens tamoxifen and fulvestrant. Cancer Research. 66: 11954-66. PMID 17178894 DOI: 10.1158/0008-5472.Can-06-1666  0.429
2006 Yan PS, Venkataramu C, Ibrahim A, Liu JC, Shen RZ, Diaz NM, Centeno B, Weber F, Leu YW, Shapiro CL, Eng C, Yeatman TJ, Huang TH. Mapping geographic zones of cancer risk with epigenetic biomarkers in normal breast tissue. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 6626-36. PMID 17121881 DOI: 10.1158/1078-0432.Ccr-06-0467  0.393
2006 Felsberg J, Yan PS, Huang TH, Milde U, Schramm J, Wiestler OD, Reifenberger G, Pietsch T, Waha A. DNA methylation and allelic losses on chromosome arm 14q in oligodendroglial tumours. Neuropathology and Applied Neurobiology. 32: 517-24. PMID 16972885 DOI: 10.1111/J.1365-2990.2006.00759.X  0.333
2006 Beima KM, Miazgowicz MM, Lewis MD, Yan PS, Huang TH, Weinmann AS. T-bet binding to newly identified target gene promoters is cell type-independent but results in variable context-dependent functional effects. The Journal of Biological Chemistry. 281: 11992-2000. PMID 16473879 DOI: 10.1074/Jbc.M513613200  0.336
2006 Cheng AS, Jin VX, Fan M, Smith LT, Liyanarachchi S, Yan PS, Leu YW, Chan MW, Plass C, Nephew KP, Davuluri RV, Huang TH. Combinatorial analysis of transcription factor partners reveals recruitment of c-MYC to estrogen receptor-alpha responsive promoters. Molecular Cell. 21: 393-404. PMID 16455494 DOI: 10.1016/J.Molcel.2005.12.016  0.348
2005 Chan MW, Wei SH, Wen P, Wang Z, Matei DE, Liu JC, Liyanarachchi S, Brown R, Nephew KP, Yan PS, Huang TH. Hypermethylation of 18S and 28S ribosomal DNAs predicts progression-free survival in patients with ovarian cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 7376-83. PMID 16243810 DOI: 10.1158/1078-0432.Ccr-05-1100  0.487
2005 Balch C, Yan P, Craft T, Young S, Skalnik DG, Huang TH, Nephew KP. Antimitogenic and chemosensitizing effects of the methylation inhibitor zebularine in ovarian cancer. Molecular Cancer Therapeutics. 4: 1505-14. PMID 16227399 DOI: 10.1158/1535-7163.Mct-05-0216  0.438
2005 Wu Y, Halverson G, Basir Z, Strawn E, Yan P, Guo S. Aberrant methylation at HOXA10 may be responsible for its aberrant expression in the endometrium of patients with endometriosis. American Journal of Obstetrics and Gynecology. 193: 371-380. PMID 16098858 DOI: 10.1016/J.Ajog.2005.01.034  0.36
2005 van Doorn R, Zoutman WH, Dijkman R, de Menezes RX, Commandeur S, Mulder AA, van der Velden PA, Vermeer MH, Willemze R, Yan PS, Huang TH, Tensen CP. Epigenetic profiling of cutaneous T-cell lymphoma: promoter hypermethylation of multiple tumor suppressor genes including BCL7a, PTPRG, and p73. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 3886-96. PMID 15897551 DOI: 10.1200/Jco.2005.11.353  0.447
2005 Waha A, Güntner S, Huang TH, Yan PS, Arslan B, Pietsch T, Wiestler OD, Waha A. Epigenetic silencing of the protocadherin family member PCDH-gamma-A11 in astrocytomas. Neoplasia (New York, N.Y.). 7: 193-9. PMID 15799819 DOI: 10.1593/Neo.04490  0.34
2005 Testa A, Donati G, Yan P, Romani F, Huang TH-, Viganò MA, Mantovani R. Chromatin immunoprecipitation (ChIP) on chip experiments uncover a widespread distribution of NF-Y binding CCAAT sites outside of core promoters Journal of Biological Chemistry. 280: 13606-13615. PMID 15647281 DOI: 10.1074/Jbc.M414039200  0.322
2004 Waha A, Rodrigues FJ, Waha A, Meyer-Puttlitz B, Cavenee WK, Huang TH, Wiestler OD, Yan PS. Methylation Profiling Identifies Epigenetic Markers for High-grade Gliomas. Cancer Genomics & Proteomics. 1: 209-214. PMID 31394655  0.312
2004 Leu YW, Yan PS, Fan M, Jin VX, Liu JC, Curran EM, Welshons WV, Wei SH, Davuluri RV, Plass C, Nephew KP, Huang TH. Loss of estrogen receptor signaling triggers epigenetic silencing of downstream targets in breast cancer. Cancer Research. 64: 8184-92. PMID 15548683 DOI: 10.1158/0008-5472.Can-04-2045  0.487
2004 Yan PS, Wei SH, Huang TH. Methylation-specific oligonucleotide microarray. Methods in Molecular Biology (Clifton, N.J.). 287: 251-60. PMID 15273417 DOI: 10.1385/1-59259-828-5:251  0.466
2004 Kondo Y, Shen L, Yan PS, Huang TH, Issa JP. Chromatin immunoprecipitation microarrays for identification of genes silenced by histone H3 lysine 9 methylation. Proceedings of the National Academy of Sciences of the United States of America. 101: 7398-403. PMID 15123805 DOI: 10.1073/Pnas.0306641101  0.451
2004 Waha A, Felsberg J, Ehrentaut D, Huang TH, Yan P, Wiestler O, Pietsch T. Genome wide methylation analysis of gliomas by a microarray based technology Klinische Padiatrie. 216. DOI: 10.1055/S-2004-828599  0.359
2003 Yan PS, Shi H, Rahmatpanah F, Hsiau TH, Hsiau AH, Leu YW, Liu JC, Huang TH. Differential distribution of DNA methylation within the RASSF1A CpG island in breast cancer. Cancer Research. 63: 6178-86. PMID 14559801  0.395
2003 Leu YW, Rahmatpanah F, Shi H, Wei SH, Liu JC, Yan PS, Huang TH. Double RNA interference of DNMT3b and DNMT1 enhances DNA demethylation and gene reactivation. Cancer Research. 63: 6110-5. PMID 14559786  0.365
2003 Yang H, Chen CM, Yan P, Huang THM, Shi H, Burger M, Nimmrich I, Maier S, Berlin K, Caldwell CW. The androgen receptor gene is preferentially hypermethylated in follicular non-Hodgkin's lymphomas Clinical Cancer Research. 9: 4034-4042. PMID 14519624  0.332
2003 Chen CM, Chen HL, Hsiau TH, Hsiau AH, Shi H, Brock GJ, Wei SH, Caldwell CW, Yan PS, Huang TH. Methylation target array for rapid analysis of CpG island hypermethylation in multiple tissue genomes. The American Journal of Pathology. 163: 37-45. PMID 12819009 DOI: 10.1016/S0002-9440(10)63628-0  0.478
2003 Mao DY, Watson JD, Yan PS, Barsyte-Lovejoy D, Khosravi F, Wong WW, Farnham PJ, Huang TH, Penn LZ. Analysis of Myc bound loci identified by CpG island arrays shows that Max is essential for Myc-dependent repression. Current Biology : Cb. 13: 882-6. PMID 12747840 DOI: 10.1016/S0960-9822(03)00297-5  0.383
2003 Shi H, Wei SH, Leu YW, Rahmatpanah F, Liu JC, Yan PS, Nephew KP, Huang TH. Triple analysis of the cancer epigenome: an integrated microarray system for assessing gene expression, DNA methylation, and histone acetylation. Cancer Research. 63: 2164-71. PMID 12727835  0.396
2003 Wells J, Yan PS, Cechvala M, Huang T, Farnham PJ. Identification of novel pRb binding sites using CpG microarrays suggests that E2F recruits pRb to specific genomic sites during S phase. Oncogene. 22: 1445-60. PMID 12629508 DOI: 10.1038/Sj.Onc.1206264  0.318
2003 Shi H, Maier S, Nimmrich I, Yan PS, Caldwell CW, Olek A, Huang TH. Oligonucleotide-based microarray for DNA methylation analysis: principles and applications. Journal of Cellular Biochemistry. 88: 138-43. PMID 12461783 DOI: 10.1002/Jcb.10313  0.497
2002 Yan PS, Chen CM, Shi H, Rahmatpanah F, Wei SH, Huang TH. Applications of CpG island microarrays for high-throughput analysis of DNA methylation. The Journal of Nutrition. 132: 2430S-2434S. PMID 12163706 DOI: 10.1093/Jn/132.8.2430S  0.462
2002 Yan PS, Efferth T, Chen HL, Lin J, Rödel F, Fuzesi L, Huang TH. Use of CpG island microarrays to identify colorectal tumors with a high degree of concurrent methylation. Methods (San Diego, Calif.). 27: 162-9. PMID 12095276 DOI: 10.1016/S1046-2023(02)00070-1  0.414
2002 Shi H, Yan PS, Chen CM, Rahmatpanah F, Lofton-Day C, Caldwell CW, Huang TH. Expressed CpG island sequence tag microarray for dual screening of DNA hypermethylation and gene silencing in cancer cells. Cancer Research. 62: 3214-20. PMID 12036936  0.416
2002 Yan PS, Wei SH, Huang TH. Differential methylation hybridization using CpG island arrays. Methods in Molecular Biology (Clifton, N.J.). 200: 87-100. PMID 11951657 DOI: 10.1385/1-59259-182-5:087  0.377
2002 Weinmann AS, Yan PS, Oberley MJ, Huang TH, Farnham PJ. Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis. Genes & Development. 16: 235-44. PMID 11799066 DOI: 10.1101/Gad.943102  0.394
2002 Gitan RS, Shi H, Chen CM, Yan PS, Huang TH. Methylation-specific oligonucleotide microarray: a new potential for high-throughput methylation analysis. Genome Research. 12: 158-64. PMID 11779841 DOI: 10.1101/Gr.202801  0.437
2001 Malik K, Yan P, Huang TH-, Brown KW. Wilms' tumor: a paradigm for the new genetics. Oncology Research. 12: 441-449. PMID 11939407 DOI: 10.3727/096504001108747440  0.344
2001 Ahluwalia A, Yan P, Hurteau JA, Bigsby RM, Jung SH, Huang TH, Nephew KP. DNA methylation and ovarian cancer. I. Analysis of CpG island hypermethylation in human ovarian cancer using differential methylation hybridization. Gynecologic Oncology. 82: 261-8. PMID 11531277 DOI: 10.1006/Gyno.2001.6291  0.461
2001 Huang TH, Shi H, Rahmatpanah F, Yan P. Dissecting complex genetic and epigenetic alterations in cancer genomes using CpG island microarrays Nature Genetics. 27: 60-61. DOI: 10.1038/87126  0.379
2001 Ahluwalia A, Yan P, Huang T, Nephew K. Methylation: a predictor of chemotherapy response in ovarian cancer? Nature Genetics. 27: 38-38. DOI: 10.1038/86970  0.404
2000 Yan PS, Perry MR, Laux DE, Asare AL, Caldwell CW, Huang TH. CpG island arrays: an application toward deciphering epigenetic signatures of breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 6: 1432-8. PMID 10778974 DOI: 10.1038/14328  0.376
2000 Yan PS, Rodriguez FJ, Laux DE, Perry MR, Standiford SB, Huang TH. Hypermethylation of ribosomal DNA in human breast carcinoma. British Journal of Cancer. 82: 514-7. PMID 10682657 DOI: 10.1054/Bjoc.1999.0955  0.424
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