Randy E. Sacco - Publications

Affiliations: 
Veterinary Microbiology and Preventative Medicine Iowa State University, Ames, IA, United States 
Area:
Immunology, Virology Biology, Cell Biology

60 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 McGill JL, Sacco RE. The Immunology of Bovine Respiratory Disease: Recent Advancements. The Veterinary Clinics of North America. Food Animal Practice. PMID 32327252 DOI: 10.1016/J.Cvfa.2020.03.002  0.379
2019 Hofstetter AR, Sacco RE. Oxidative stress pathway gene transcription after bovine respiratory syncytial virus infection in vitro and ex vivo. Veterinary Immunology and Immunopathology. 219: 109956. PMID 31706084 DOI: 10.1016/J.Vetimm.2019.109956  0.462
2019 McGill JL, Kelly SM, Guerra-Maupome M, Winkley E, Henningson J, Narasimhan B, Sacco RE. Vitamin A deficiency impairs the immune response to intranasal vaccination and RSV infection in neonatal calves. Scientific Reports. 9: 15157. PMID 31641172 DOI: 10.1038/S41598-019-51684-X  0.354
2019 Putz EJ, Eder JM, Reinhardt TA, Sacco RE, Casas E, Lippolis JD. Differential phenotype of immune cells in blood and milk following pegylated granulocyte colony-stimulating factor therapy during a chronic Staphylococcus aureus infection in lactating Holsteins. Journal of Dairy Science. 102: 9268-9284. PMID 31400902 DOI: 10.3168/jds.2019-16448  0.317
2019 Guerra-Maupome M, Palmer MV, McGill JL, Sacco RE. Utility of the Neonatal Calf Model for Testing Vaccines and Intervention Strategies for Use against Human RSV Infection. Vaccines. 7. PMID 30626099 DOI: 10.3390/Vaccines7010007  0.45
2018 Register KB, Olsen SC, Sacco RE, Ridpath J, Falkenberg S, Briggs R, Kanipe C, Madison R. Relative virulence in bison and cattle of bison-associated genotypes of Mycoplasma bovis. Veterinary Microbiology. 222: 55-63. PMID 30080673 DOI: 10.1016/J.Vetmic.2018.06.020  0.317
2018 McGill JL, Kelly SM, Kumar P, Speckhart S, Haughney SL, Henningson J, Narasimhan B, Sacco RE. Efficacy of mucosal polyanhydride nanovaccine against respiratory syncytial virus infection in the neonatal calf. Scientific Reports. 8: 3021. PMID 29445124 DOI: 10.1038/S41598-018-21292-2  0.46
2018 Eberle KC, Venn-Watson SK, Jensen ED, LaBresh J, Sullivan Y, Kakach L, Sacco RE. Development and testing of species-specific ELISA assays to measure IFN-γ and TNF-α in bottlenose dolphins (Tursiops truncatus). Plos One. 13: e0190786. PMID 29304133 DOI: 10.1371/Journal.Pone.0190786  0.355
2017 Hofstetter AR, Eberle KC, Venn-Watson SK, Jensen ED, Porter TJ, Waters TE, Sacco RE. Monitoring bottlenose dolphin leukocyte cytokine mRNA responsiveness by qPCR. Plos One. 12: e0189437. PMID 29272269 DOI: 10.1371/Journal.Pone.0189437  0.312
2017 Lippolis JD, Holman DB, Brunelle BW, Thacker TC, Bearson BL, Reinhardt TA, Sacco RE, Casey TA. Genomic and Transcriptomic Analysis of Escherichia coli Strains Associated with Persistent and Transient Bovine Mastitis and the Role of Colanic Acid. Infection and Immunity. PMID 29061709 DOI: 10.1128/Iai.00566-17  0.346
2017 Thacker TC, Lippolis JD, Brunelle BW, Casey TA, Reinhardt TA, Sacco RE, Holman DB. Genome Sequences of Escherichia coli Strains That Cause Persistent and Transient Mastitis. Genome Announcements. 5. PMID 28839016 DOI: 10.1128/Genomea.00775-17  0.321
2016 Schaut RG, Ridpath JF, Sacco RE. Bovine Viral Diarrhea Virus Type 2 Impairs Macrophage Responsiveness to Toll-Like Receptor Ligation with the Exception of Toll-Like Receptor 7. Plos One. 11: e0159491. PMID 27420479 DOI: 10.1371/Journal.Pone.0159491  0.739
2016 McGill JL, Rusk RA, Guerra-Maupome M, Briggs RE, Sacco RE. Bovine Gamma Delta T Cells Contribute to Exacerbated IL-17 Production in Response to Co-Infection with Bovine RSV and Mannheimia haemolytica. Plos One. 11: e0151083. PMID 26942409 DOI: 10.1371/Journal.Pone.0151083  0.45
2016 McGill JL, Sacco RE. γδ T cells and the immune response to respiratory syncytial virus infection. Veterinary Immunology and Immunopathology. PMID 26923879 DOI: 10.1016/J.Vetimm.2016.02.012  0.476
2015 Eberle KC, McGill JL, Reinhardt TA, Sacco RE. Parainfluenza Virus 3 Blocks Antiviral Mediators Downstream of the Interferon Lambda Receptor by Modulating Stat1 Phosphorylation. Journal of Virology. 90: 2948-58. PMID 26719274 DOI: 10.1128/Jvi.02502-15  0.469
2015 Sacco RE, Durbin RK, Durbin JE. Animal models of respiratory syncytial virus infection and disease. Current Opinion in Virology. 13: 117-22. PMID 26176495 DOI: 10.1016/J.Coviro.2015.06.003  0.437
2015 Eberle KC, Neill JD, Venn-Watson SK, McGill JL, Sacco RE. Novel Atlantic bottlenose dolphin parainfluenza virus TtPIV-1 clusters with bovine PIV-3 genotype B strains. Virus Genes. 51: 198-208. PMID 26174699 DOI: 10.1007/S11262-015-1224-7  0.395
2015 Hansen TR, Smirnova NP, Webb BT, Bielefeldt-Ohmann H, Sacco RE, Van Campen H. Innate and adaptive immune responses to in utero infection with bovine viral diarrhea virus. Animal Health Research Reviews / Conference of Research Workers in Animal Diseases. 16: 15-26. PMID 26050568 DOI: 10.1017/S1466252315000122  0.515
2015 Schaut RG, McGill JL, Neill JD, Ridpath JF, Sacco RE. Bovine viral diarrhea virus type 2 in vivo infection modulates TLR4 responsiveness in differentiated myeloid cells which is associated with decreased MyD88 expression. Virus Research. 208: 44-55. PMID 26043978 DOI: 10.1016/J.Virusres.2015.05.017  0.748
2014 Nonnecke BJ, McGill JL, Ridpath JF, Sacco RE, Lippolis JD, Reinhardt TA. Acute phase response elicited by experimental bovine diarrhea virus (BVDV) infection is associated with decreased vitamin D and E status of vitamin-replete preruminant calves Journal of Dairy Science. 97: 5566-5579. PMID 25022687 DOI: 10.3168/Jds.2014-8293  0.43
2014 Falkenberg SM, Johnson C, Bauermann FV, McGill J, Palmer MV, Sacco RE, Ridpath JF. Changes observed in the thymus and lymph nodes 14 days after exposure to BVDV field strains of enhanced or typical virulence in neonatal calves. Veterinary Immunology and Immunopathology. 160: 70-80. PMID 24809640 DOI: 10.1016/J.Vetimm.2014.03.018  0.464
2014 McGill JL, Sacco RE, Baldwin CL, Telfer JC, Palmer MV, Waters WR. The role of gamma delta T cells in immunity to Mycobacterium bovis infection in cattle. Veterinary Immunology and Immunopathology. 159: 133-43. PMID 24636303 DOI: 10.1016/J.Vetimm.2014.02.010  0.431
2014 McGill JL, Sacco RE, Baldwin CL, Telfer JC, Palmer MV, Waters WR. Specific recognition of mycobacterial protein and peptide antigens by γδ T cell subsets following infection with virulent Mycobacterium bovis. Journal of Immunology (Baltimore, Md. : 1950). 192: 2756-69. PMID 24532582 DOI: 10.4049/Jimmunol.1302567  0.411
2014 Smirnova NP, Webb BT, McGill JL, Schaut RG, Bielefeldt-Ohmann H, Van Campen H, Sacco RE, Hansen TR. Induction of interferon-gamma and downstream pathways during establishment of fetal persistent infection with bovine viral diarrhea virus. Virus Research. 183: 95-106. PMID 24530541 DOI: 10.1016/J.Virusres.2014.02.002  0.747
2014 Sacco RE, McGill JL, Pillatzki AE, Palmer MV, Ackermann MR. Respiratory syncytial virus infection in cattle. Veterinary Pathology. 51: 427-36. PMID 24009269 DOI: 10.1177/0300985813501341  0.473
2013 Derscheid RJ, van Geelen A, McGill JL, Gallup JM, Cihlar T, Sacco RE, Ackermann MR. Human respiratory syncytial virus Memphis 37 grown in HEp-2 cells causes more severe disease in lambs than virus grown in Vero cells. Viruses. 5: 2881-97. PMID 24284879 DOI: 10.3390/V5112881  0.421
2013 Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD. Bovine milk proteome: quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis. Journal of Proteomics. 82: 141-54. PMID 23459212 DOI: 10.1016/J.Jprot.2013.02.013  0.365
2013 McGill JL, Nonnecke BJ, Lippolis JD, Reinhardt TA, Sacco RE. Differential chemokine and cytokine production by neonatal bovine γδ T-cell subsets in response to viral toll-like receptor agonists and in vivo respiratory syncytial virus infection. Immunology. 139: 227-44. PMID 23368631 DOI: 10.1111/Imm.12075  0.444
2013 Richeson JT, Kegley EB, Powell JG, Schaut RG, Sacco RE, Ridpath JF. Weaning management of newly received beef calves with or without continuous exposure to a persistently infected bovine viral diarrhea virus pen mate: effects on rectal temperature and serum proinflammatory cytokine and haptoglobin concentrations. Journal of Animal Science. 91: 1400-8. PMID 23345551 DOI: 10.2527/Jas.2011-4875  0.704
2012 Sacco RE, McGill JL, Palmer MV, Lippolis JD, Reinhardt TA, Nonnecke BJ. Neonatal calf infection with respiratory syncytial virus: drawing parallels to the disease in human infants. Viruses. 4: 3731-53. PMID 23342375 DOI: 10.3390/V4123731  0.482
2012 Nelson CD, Reinhardt TA, Lippolis JD, Sacco RE, Nonnecke BJ. Vitamin D signaling in the bovine immune system: a model for understanding human vitamin D requirements. Nutrients. 4: 181-96. PMID 22666545 DOI: 10.3390/Nu4030181  0.321
2012 Sacco RE, Nonnecke BJ, Palmer MV, Waters WR, Lippolis JD, Reinhardt TA. Differential expression of cytokines in response to respiratory syncytial virus infection of calves with high or low circulating 25-hydroxyvitamin D3. Plos One. 7: e33074. PMID 22412984 DOI: 10.1371/Journal.Pone.0033074  0.427
2012 Sharma VK, Sacco RE, Kunkle RA, Bearson SM, Palmquist DE. Correlating levels of type III secretion and secreted proteins with fecal shedding of Escherichia coli O157:H7 in cattle. Infection and Immunity. 80: 1333-42. PMID 22252878 DOI: 10.1128/Iai.05869-11  0.31
2011 Sacco RE, Nicholson TL, Waters TE, Brockmeier SL. Porcine TLR3 characterization and expression in response to influenza virus and Bordetella bronchiseptica. Veterinary Immunology and Immunopathology. 142: 57-63. PMID 21561668 DOI: 10.1016/J.Vetimm.2011.04.008  0.474
2010 Loving CL, Brockmeier SL, Vincent AL, Palmer MV, Sacco RE, Nicholson TL. Influenza virus coinfection with Bordetella bronchiseptica enhances bacterial colonization and host responses exacerbating pulmonary lesions. Microbial Pathogenesis. 49: 237-45. PMID 20558274 DOI: 10.1016/J.Micpath.2010.06.004  0.657
2010 Fach SJ, Olivier A, Gallup JM, Waters TE, Ackermann MR, Lehmkuhl HD, Sacco RE. Differential expression of cytokine transcripts in neonatal and adult ovine alveolar macrophages in response to respiratory syncytial virus or toll-like receptor ligation. Veterinary Immunology and Immunopathology. 136: 55-64. PMID 20207014 DOI: 10.1016/J.Vetimm.2010.02.008  0.463
2009 Waters WR, Palmer MV, Nonnecke BJ, Thacker TC, Estes DM, Larsen MH, Jacobs WR, Andersen P, McNair J, Minion FC, Lyashchenko KP, Hewinson RG, Vordermeier HM, Sacco RE. Signal regulatory protein alpha (SIRPalpha) cells in the adaptive response to ESAT-6/CFP-10 protein of tuberculous mycobacteria. Plos One. 4: e6414. PMID 19641628 DOI: 10.1371/Journal.Pone.0006414  0.353
2009 Brockmeier SL, Lager KM, Grubman MJ, Brough DE, Ettyreddy D, Sacco RE, Gauger PC, Loving CL, Vorwald AC, Kehrli ME, Lehmkuhl HD. Adenovirus-mediated expression of interferon-alpha delays viral replication and reduces disease signs in swine challenged with porcine reproductive and respiratory syndrome virus. Viral Immunology. 22: 173-80. PMID 19435413 DOI: 10.1089/Vim.2008.0075  0.612
2008 Loving CL, Brockmeier SL, Vincent AL, Lager KM, Sacco RE. Differences in clinical disease and immune response of pigs challenged with a high-dose versus low-dose inoculum of porcine reproductive and respiratory syndrome virus. Viral Immunology. 21: 315-25. PMID 18788940 DOI: 10.1089/Vim.2008.0038  0.64
2007 Register KB, Sacco RE, Brockmeier SL. Immune response in mice and swine to DNA vaccines derived from the Pasteurella multocida toxin gene. Vaccine. 25: 6118-28. PMID 17590484 DOI: 10.1016/J.Vaccine.2007.05.028  0.375
2007 Fach SJ, Meyerholz DK, Gallup JM, Ackermann MR, Lehmkuhl HD, Sacco RE. Neonatal ovine pulmonary dendritic cells support bovine respiratory syncytial virus replication with enhanced interleukin (IL)-4 And IL-10 gene transcripts. Viral Immunology. 20: 119-30. PMID 17425426 DOI: 10.1089/Vim.2006.0056  0.425
2007 Loving CL, Brockmeier SL, Sacco RE. Differential type I interferon activation and susceptibility of dendritic cell populations to porcine arterivirus. Immunology. 120: 217-29. PMID 17116172 DOI: 10.1111/J.1365-2567.2006.02493.X  0.63
2006 Loving CL, Brockmeier SL, Ma W, Richt JA, Sacco RE. Innate cytokine responses in porcine macrophage populations: evidence for differential recognition of double-stranded RNA. Journal of Immunology (Baltimore, Md. : 1950). 177: 8432-9. PMID 17142740 DOI: 10.4049/Jimmunol.177.12.8432  0.641
2006 Fach SJ, Brockmeier SL, Hobbs LA, Lehmkuhl HD, Sacco RE. Pulmonary dendritic cells isolated from neonatal and adult ovine lung tissue. Veterinary Immunology and Immunopathology. 112: 171-82. PMID 16621027 DOI: 10.1016/J.Vetimm.2006.02.012  0.328
2004 Meyerholz DK, Grubor B, Fach SJ, Sacco RE, Lehmkuhl HD, Gallup JM, Ackermann MR. Reduced clearance of respiratory syncytial virus infection in a preterm lamb model. Microbes and Infection / Institut Pasteur. 6: 1312-9. PMID 15555538 DOI: 10.1016/J.Micinf.2004.08.006  0.441
2003 Brogden KA, Heidari M, Sacco RE, Palmquist D, Guthmiller JM, Johnson GK, Jia HP, Tack BF, McCray PB. Defensin-induced adaptive immunity in mice and its potential in preventing periodontal disease. Oral Microbiology and Immunology. 18: 95-9. PMID 12654098 DOI: 10.1034/J.1399-302X.2003.00047.X  0.385
2003 Waters WR, Palmer MV, Olsen SC, Sacco RE, Whipple DL. Immune responses of elk to Mycobacterium bovis bacillus Calmette Guerin vaccination. Vaccine. 21: 1518-26. PMID 12615449 DOI: 10.1016/S0264-410X(02)00678-3  0.368
2002 Murphy ER, Sacco RE, Dickenson A, Metzger DJ, Hu Y, Orndorff PE, Connell TD. BhuR, a virulence-associated outer membrane protein of Bordetella avium, is required for the acquisition of iron from heme and hemoproteins. Infection and Immunity. 70: 5390-403. PMID 12228263 DOI: 10.1128/Iai.70.10.5390-5403.2002  0.309
2002 Sacco R, Hagen M, Sandor M, Weinstock JV, Lynch RG. Established T(H1) granulomatous responses induced by active Mycobacterium avium infection switch to T(H2) following challenge with Schistosoma mansoni. Clinical Immunology (Orlando, Fla.). 104: 274-81. PMID 12217338 DOI: 10.1006/clim.2002.5263  0.317
2002 Waters WR, Sacco RE, Fach SJ, Palmer MV, Olsen SC, Kreeger TJ. Analysis of mitogen-stimulated lymphocyte subset proliferation and nitric oxide production by peripheral blood mononuclear cells of captive elk (Cervus elaphus). Journal of Wildlife Diseases. 38: 344-51. PMID 12038134 DOI: 10.7589/0090-3558-38.2.344  0.34
2002 Waters WR, Palmer MV, Sacco RE, Whipple DL. Nitric oxide production as an indication of Mycobacterium bovis infection in white-tailed deer (Odocoileus virginianus). Journal of Wildlife Diseases. 38: 338-43. PMID 12038133 DOI: 10.7589/0090-3558-38.2.338  0.395
2001 Zhao C, Nguyen T, Liu L, Sacco RE, Brogden KA, Lehrer RI. Gallinacin-3, an inducible epithelial beta-defensin in the chicken. Infection and Immunity. 69: 2684-91. PMID 11254635 DOI: 10.1128/Iai.69.4.2684-2691.2001  0.3
2000 Waters WR, Palmer MV, Wannemuehler MJ, Sacco RE, Harp JA. B cells are required for the induction of intestinal inflammatory lesions in TCRα-deficient mice persistently infected with cryptosporidium parvum Journal of Parasitology. 86: 1073-1077. PMID 11128483 DOI: 10.1645/0022-3395(2000)086[1073:Bcarft]2.0.Co;2  0.342
2000 Waters WR, Hontecillas R, Sacco RE, Zuckermann FA, Harkins KR, Bassaganya-Riera J, Wannemuehler MJ. Antigen-specific proliferation of porcine CD8alphaalpha cells to an extracellular bacterial pathogen. Immunology. 101: 333-41. PMID 11106936 DOI: 10.1046/J.1365-2567.2000.00114.X  0.335
2000 Sacco RE, Nestor KE, Kunkle RA. Genetic Variation in Response of Turkeys to Experimental Infection with Bordetella avium Avian Diseases. 44: 197. DOI: 10.2307/1592525  0.316
1999 Waters WR, Pesch BA, Hontecillas R, Sacco RE, Zuckermann FA, Wannemuehler MJ. Cellular immune responses of pigs induced by vaccination with either a whole cell sonicate or pepsin-digested Brachyspira (Serpulina) hyodysenteriae bacterin Vaccine. 18: 711-719. PMID 10547431 DOI: 10.1016/S0264-410X(99)00266-2  0.367
1999 Waters WR, Sacco RE, Dorn AD, Hontecillas R, Zuckermann FA, Wannemuehler MJ. Systemic and mucosal immune responses of pigs to parenteral immunization with a pepsin-digested Serpulina hyodysenteriae bacterin Veterinary Immunology and Immunopathology. 69: 75-87. PMID 10490236 DOI: 10.1016/S0165-2427(99)00043-4  0.422
1998 Sacco RE, Haynes JS, Harp JA, Waters WR, Wannemuehler MJ. Cryptosporidium parvum initiates inflammatory bowel disease in germfree T cell receptor-α-deficient mice American Journal of Pathology. 153: 1717-1722. PMID 9846962 DOI: 10.1016/S0002-9440(10)65686-6  0.305
1996 Harp JA, Sacco RE. Development of Cellular Immune Functions in Neonatal to Weanling Mice: Relationship to Cryptosporidium parvum Infection The Journal of Parasitology. 82: 245. DOI: 10.2307/3284155  0.368
1994 Harp JA, Whitmire WM, Sacco R. In vitro Proliferation and Production of Gamma Interferon by Murine CD4 + Cells in Response to Cryptosporidium parvum Antigen The Journal of Parasitology. 80: 67. DOI: 10.2307/3283347  0.337
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