| Year |
Citation |
Score |
| 2023 |
Gül E, Bakkeren E, Salazar G, Steiger Y, Abi Younes A, Clerc M, Christen P, Fattinger SA, Nguyen BD, Kiefer P, Slack E, Ackermann M, Vorholt JA, Sunagawa S, Diard M, ... Hardt WD, et al. The microbiota conditions a gut milieu that selects for wild-type Salmonella Typhimurium virulence. Plos Biology. 21: e3002253. PMID 37651408 DOI: 10.1371/journal.pbio.3002253 |
0.385 |
|
| 2023 |
Gül E, Fattinger SA, Sellin ME, Hardt WD. Epithelial inflammasomes, gasdermins, and mucosal inflammation - Lessons from Salmonella and Shigella infected mice. Seminars in Immunology. 70: 101812. PMID 37562110 DOI: 10.1016/j.smim.2023.101812 |
0.349 |
|
| 2023 |
Gül E, Enz U, Maurer L, Abi Younes A, Fattinger SA, Nguyen BD, Hausmann A, Furter M, Barthel M, Sellin ME, Hardt WD. Intraluminal neutrophils limit epithelium damage by reducing pathogen assault on intestinal epithelial cells during Salmonella gut infection. Plos Pathogens. 19: e1011235. PMID 37384776 DOI: 10.1371/journal.ppat.1011235 |
0.387 |
|
| 2023 |
Laganenka L, Lee JW, Malfertheiner L, Dieterich CL, Fuchs L, Piel J, von Mering C, Sourjik V, Hardt WD. Chemotaxis and autoinducer-2 signalling mediate colonization and contribute to co-existence of Escherichia coli strains in the murine gut. Nature Microbiology. PMID 36624229 DOI: 10.1038/s41564-022-01286-7 |
0.33 |
|
| 2022 |
Newson JP, Gaissmaier MS, McHugh SC, Hardt WD. Studying antibiotic persistence in vivo using the model organism Salmonella Typhimurium. Current Opinion in Microbiology. 70: 102224. PMID 36335713 DOI: 10.1016/j.mib.2022.102224 |
0.338 |
|
| 2022 |
Ek V, Fattinger SA, Florbrant A, Hardt WD, Di Martino ML, Eriksson J, Sellin ME. A motile doublet form of Salmonella Typhimurium diversifies target search behavior at the epithelial surface. Molecular Microbiology. PMID 35332598 DOI: 10.1111/mmi.14898 |
0.371 |
|
| 2021 |
Fattinger SA, Sellin ME, Hardt WD. Salmonella effector driven invasion of the gut epithelium: breaking in and setting the house on fire. Current Opinion in Microbiology. 64: 9-18. PMID 34492596 DOI: 10.1016/j.mib.2021.08.007 |
0.33 |
|
| 2020 |
Fattinger SA, Sellin ME, Hardt WD. Epithelial inflammasomes in the defense against Salmonella gut infection. Current Opinion in Microbiology. 59: 86-94. PMID 33128958 DOI: 10.1016/j.mib.2020.09.014 |
0.398 |
|
| 2020 |
Hausmann A, Hardt WD. Elucidating Host-Microbe Interactions in vivo by Studying Population Dynamics Using Neutral Genetic Tags. Immunology. PMID 32931019 DOI: 10.1111/Imm.13266 |
0.353 |
|
| 2020 |
Kreuzer M, Hardt WD. How Food Affects Colonization Resistance Against Enteropathogenic Bacteria. Annual Review of Microbiology. PMID 32692613 DOI: 10.1146/Annurev-Micro-020420-013457 |
0.335 |
|
| 2020 |
Selkrig J, Li N, Hausmann A, Mangan MSJ, Zietek M, Mateus A, Bobonis J, Sueki A, Imamura H, El Debs B, Sigismondo G, Florea BI, Overkleeft HS, Kopitar-Jerala N, Turk B, ... ... Hardt WD, et al. Spatiotemporal proteomics uncovers cathepsin-dependent macrophage cell death during Salmonella infection. Nature Microbiology. PMID 32514074 DOI: 10.1038/S41564-020-0736-7 |
0.471 |
|
| 2020 |
Bakkeren E, Diard M, Hardt WD. Evolutionary causes and consequences of bacterial antibiotic persistence. Nature Reviews. Microbiology. PMID 32461608 DOI: 10.1038/S41579-020-0378-Z |
0.358 |
|
| 2020 |
Nguyen BD, Cuenca V M, Hartl J, Gül E, Bauer R, Meile S, Rüthi J, Margot C, Heeb L, Besser F, Escriva PP, Fetz C, Furter M, Laganenka L, Keller P, ... ... Hardt WD, et al. Import of Aspartate and Malate by DcuABC Drives H/Fumarate Respiration to Promote Initial Salmonella Gut-Lumen Colonization in Mice. Cell Host & Microbe. PMID 32416061 DOI: 10.1016/J.Chom.2020.04.013 |
0.368 |
|
| 2020 |
Fattinger SA, Böck D, Di Martino ML, Deuring S, Samperio Ventayol P, Ek V, Furter M, Kreibich S, Bosia F, Müller-Hauser AA, Nguyen BD, Rohde M, Pilhofer M, Hardt WD, Sellin ME. Salmonella typhimurium discreet-invasion of the murine gut absorptive epithelium. Plos Pathogens. 16: e1008503. PMID 32365138 DOI: 10.1371/Journal.Ppat.1008503 |
0.421 |
|
| 2020 |
Hausmann A, Russo G, Grossmann J, Zünd M, Schwank G, Aebersold R, Liu Y, Sellin ME, Hardt WD. Germ-Free and Microbiota-Associated Mice yield Small Intestinal Epithelial Organoids with Equivalent and Robust Transcriptome/Proteome Expression Phenotypes. Cellular Microbiology. e13191. PMID 32068945 DOI: 10.1111/Cmi.13191 |
0.367 |
|
| 2020 |
Hausmann A, Böck D, Geiser P, Berthold DL, Fattinger SA, Furter M, Bouman JA, Barthel-Scherrer M, Lang CM, Bakkeren E, Kolinko I, Diard M, Bumann D, Slack E, Regoes RR, ... ... Hardt WD, et al. Intestinal epithelial NAIP/NLRC4 restricts systemic dissemination of the adapted pathogen Salmonella Typhimurium due to site-specific bacterial PAMP expression. Mucosal Immunology. PMID 31953493 DOI: 10.1038/S41385-019-0247-0 |
0.449 |
|
| 2019 |
Wotzka SY, Kreuzer M, Maier L, Arnoldini M, Nguyen BD, Brachmann AO, Berthold DL, Zünd M, Hausmann A, Bakkeren E, Hoces D, Gül E, Beutler M, Dolowschiak T, Zimmermann M, ... ... Hardt WD, et al. Escherichia coli limits Salmonella Typhimurium infections after diet shifts and fat-mediated microbiota perturbation in mice. Nature Microbiology. PMID 31591555 DOI: 10.1038/S41564-019-0568-5 |
0.405 |
|
| 2019 |
Bakkeren E, Huisman JS, Fattinger SA, Hausmann A, Furter M, Egli A, Slack E, Sellin ME, Bonhoeffer S, Regoes RR, Diard M, Hardt WD. Salmonella persisters promote the spread of antibiotic resistance plasmids in the gut. Nature. 573: 276-280. PMID 31485077 DOI: 10.1038/S41586-019-1521-8 |
0.42 |
|
| 2019 |
Furter M, Sellin ME, Hansson GC, Hardt WD. Mucus Architecture and Near-Surface Swimming Affect Distinct Salmonella Typhimurium Infection Patterns along the Murine Intestinal Tract. Cell Reports. 27: 2665-2678.e3. PMID 31141690 DOI: 10.1016/J.Celrep.2019.04.106 |
0.404 |
|
| 2019 |
Di Martino ML, Ek V, Hardt WD, Eriksson J, Sellin ME. Barcoded Consortium Infections Resolve Cell Type-Dependent Salmonella enterica Serovar Typhimurium Entry Mechanisms. Mbio. 10. PMID 31113898 DOI: 10.1128/Mbio.00603-19 |
0.494 |
|
| 2019 |
Bansept F, Schumann-Moor K, Diard M, Hardt WD, Slack E, Loverdo C. Enchained growth and cluster dislocation: A possible mechanism for microbiota homeostasis. Plos Computational Biology. 15: e1006986. PMID 31050663 DOI: 10.1371/Journal.Pcbi.1006986 |
0.415 |
|
| 2019 |
Balaban NQ, Helaine S, Lewis K, Ackermann M, Aldridge B, Andersson DI, Brynildsen MP, Bumann D, Camilli A, Collins JJ, Dehio C, Fortune S, Ghigo JM, Hardt WD, Harms A, et al. Publisher Correction: Definitions and guidelines for research on antibiotic persistence. Nature Reviews. Microbiology. PMID 31036919 DOI: 10.1038/S41579-019-0207-4 |
0.491 |
|
| 2019 |
Balaban NQ, Helaine S, Lewis K, Ackermann M, Aldridge B, Andersson DI, Brynildsen MP, Bumann D, Camilli A, Collins JJ, Dehio C, Fortune S, Ghigo JM, Hardt WD, Harms A, et al. Definitions and guidelines for research on antibiotic persistence. Nature Reviews. Microbiology. PMID 30980069 DOI: 10.1038/S41579-019-0196-3 |
0.553 |
|
| 2019 |
Hausmann A, Hardt WD. The Interplay between Serovar Typhimurium and the Intestinal Mucosa during Oral Infection. Microbiology Spectrum. 7. PMID 30953432 DOI: 10.1128/Microbiolspec.Bai-0004-2019 |
0.482 |
|
| 2019 |
Liu Y, Mi Y, Mueller T, Kreibich S, Williams EG, Van Drogen A, Borel C, Frank M, Germain PL, Bludau I, Mehnert M, Seifert M, Emmenlauer M, Sorg I, Bezrukov F, ... ... Hardt WD, et al. Multi-omic measurements of heterogeneity in HeLa cells across laboratories. Nature Biotechnology. PMID 30778230 DOI: 10.1038/S41587-019-0037-Y |
0.321 |
|
| 2019 |
Proietti M, Perruzza L, Scribano D, Pellegrini G, D'Antuono R, Strati F, Raffaelli M, Gonzalez SF, Thelen M, Hardt WD, Slack E, Nicoletti M, Grassi F. ATP released by intestinal bacteria limits the generation of protective IgA against enteropathogens. Nature Communications. 10: 250. PMID 30651557 DOI: 10.1038/S41467-018-08156-Z |
0.408 |
|
| 2019 |
Westermann AJ, Venturini E, Sellin ME, Förstner KU, Hardt WD, Vogel J. The Major RNA-Binding Protein ProQ Impacts Virulence Gene Expression in Salmonella enterica Serovar Typhimurium. Mbio. 10. PMID 30602583 DOI: 10.1128/Mbio.02504-18 |
0.414 |
|
| 2018 |
Wotzka SY, Kreuzer M, Maier L, Zünd M, Schlumberger M, Nguyen B, Fox M, Pohl D, Heinrich H, Rogler G, Biedermann L, Scharl M, Sunagawa S, Hardt WD, Misselwitz B. Microbiota stability in healthy individuals after single-dose lactulose challenge-A randomized controlled study. Plos One. 13: e0206214. PMID 30359438 DOI: 10.1371/Journal.Pone.0206214 |
0.311 |
|
| 2018 |
Daga N, Eicher S, Kannan A, Casanova A, Low SH, Kreibich S, Andritschke D, Emmenlauer M, Jenkins JL, Hardt WD, Greber UF, Dehio C, von Mering C. Growth-restricting effects of siRNA transfections: a largely deterministic combination of off-target binding and hybridization-independent competition. Nucleic Acids Research. PMID 30215772 DOI: 10.1093/Nar/Gky798 |
0.303 |
|
| 2018 |
Miki T, Okada N, Hardt WD. Inflammatory bactericidal lectin RegIIIβ: Friend or foe for the host? Gut Microbes. 9: 179-187. PMID 28985140 DOI: 10.1080/19490976.2017.1387344 |
0.481 |
|
| 2018 |
Sellin ME, Müller AA, Hardt WD. Consequences of Epithelial Inflammasome Activation by Bacterial Pathogens. Journal of Molecular Biology. 430: 193-206. PMID 28454742 DOI: 10.1016/J.Jmb.2017.03.031 |
0.456 |
|
| 2017 |
Diard M, Hardt WD. Basic Processes in -Host Interactions: Within-Host Evolution and the Transmission of the Virulent Genotype. Microbiology Spectrum. 5. PMID 28884670 DOI: 10.1128/Microbiolspec.Mtbp-0012-2016 |
0.488 |
|
| 2017 |
Takizawa H, Fritsch K, Kovtonyuk LV, Saito Y, Yakkala C, Jacobs K, Ahuja AK, Lopes M, Hausmann A, Hardt WD, Gomariz Á, Nombela-Arrieta C, Manz MG. Pathogen-Induced TLR4-TRIF Innate Immune Signaling in Hematopoietic Stem Cells Promotes Proliferation but Reduces Competitive Fitness. Cell Stem Cell. PMID 28736216 DOI: 10.1016/J.Stem.2017.06.013 |
0.366 |
|
| 2017 |
Diard M, Hardt WD. Evolution of bacterial virulence. Fems Microbiology Reviews. 41: 679-697. PMID 28531298 DOI: 10.1093/Femsre/Fux023 |
0.46 |
|
| 2017 |
Wotzka SY, Nguyen BD, Hardt WD. Salmonella Typhimurium Diarrhea Reveals Basic Principles of Enteropathogen Infection and Disease-Promoted DNA Exchange. Cell Host & Microbe. 21: 443-454. PMID 28407482 DOI: 10.1016/J.Chom.2017.03.009 |
0.464 |
|
| 2017 |
Moor K, Diard M, Sellin ME, Felmy B, Wotzka SY, Toska A, Bakkeren E, Arnoldini M, Bansept F, Co AD, Völler T, Minola A, Fernandez-Rodriguez B, Agatic G, Barbieri S, ... ... Hardt WD, et al. High-avidity IgA protects the intestine by enchaining growing bacteria. Nature. 544: 498-502. PMID 28405025 DOI: 10.1038/Nature22058 |
0.474 |
|
| 2017 |
Diard M, Bakkeren E, Cornuault JK, Moor K, Hausmann A, Sellin ME, Loverdo C, Aertsen A, Ackermann M, De Paepe M, Slack E, Hardt WD. Inflammation boosts bacteriophage transfer between spp. Science (New York, N.Y.). 355: 1211-1215. PMID 28302859 DOI: 10.1126/Science.Aaf8451 |
0.376 |
|
| 2017 |
Schürmann N, Forrer P, Casse O, Li J, Felmy B, Burgener AV, Ehrenfeuchter N, Hardt WD, Recher M, Hess C, Tschan-Plessl A, Khanna N, Bumann D. Myeloperoxidase targets oxidative host attacks to Salmonella and prevents collateral tissue damage. Nature Microbiology. 2: 16268. PMID 28112722 DOI: 10.1038/Nmicrobiol.2016.268 |
0.375 |
|
| 2017 |
Miki T, Goto R, Fujimoto M, Okada N, Hardt WD. The Bactericidal Lectin RegIIIβ Prolongs Gut Colonization and Enteropathy in the Streptomycin Mouse Model for Salmonella Diarrhea. Cell Host & Microbe. 21: 195-207. PMID 28111202 DOI: 10.1016/J.Chom.2016.12.008 |
0.41 |
|
| 2016 |
Andritschke D, Dilling S, Emmenlauer M, Welz T, Schmich F, Misselwitz B, Rämö P, Rottner K, Kerkhoff E, Wada T, Penninger JM, Beerenwinkel N, Horvath P, Dehio C, Hardt WD. A Genome-Wide siRNA Screen Implicates Spire1/2 in SipA-Driven Salmonella Typhimurium Host Cell Invasion. Plos One. 11: e0161965. PMID 27627128 DOI: 10.1371/Journal.Pone.0161965 |
0.494 |
|
| 2016 |
Hardt WD. Antimicrobial resistance: Survival by reversible resistance. Nature Microbiology. 1: 16072. PMID 27572844 DOI: 10.1038/Nmicrobiol.2016.72 |
0.304 |
|
| 2016 |
Colgan AM, Kröger C, Diard M, Hardt WD, Puente JL, Sivasankaran SK, Hokamp K, Hinton JC. The Impact of 18 Ancestral and Horizontally-Acquired Regulatory Proteins upon the Transcriptome and sRNA Landscape of Salmonella enterica serovar Typhimurium. Plos Genetics. 12: e1006258. PMID 27564394 DOI: 10.1371/Journal.Pgen.1006258 |
0.381 |
|
| 2016 |
Dolowschiak T, Mueller AA, Pisan LJ, Feigelman R, Felmy B, Sellin ME, Namineni S, Nguyen BD, Wotzka SY, Heikenwaelder M, von Mering C, Mueller C, Hardt WD. IFN-γ Hinders Recovery from Mucosal Inflammation during Antibiotic Therapy for Salmonella Gut Infection. Cell Host & Microbe. PMID 27453483 DOI: 10.1016/J.Chom.2016.06.008 |
0.36 |
|
| 2016 |
Müller AA, Dolowschiak T, Sellin ME, Felmy B, Verbree C, Gadient S, Westermann AJ, Vogel J, LeibundGut-Landmann S, Hardt WD. An NK Cell Perforin Response Elicited via IL-18 Controls Mucosal Inflammation Kinetics during Salmonella Gut Infection. Plos Pathogens. 12: e1005723. PMID 27341123 DOI: 10.1371/Journal.Ppat.1005723 |
0.428 |
|
| 2016 |
Curkić I, Schütz M, Oberhettinger P, Diard M, Claassen M, Linke D, Hardt WD. Epitope-Tagged Autotransporters as Single-Cell Reporters for Gene Expression by a Salmonella Typhimurium wbaP Mutant. Plos One. 11: e0154828. PMID 27149272 DOI: 10.1371/Journal.Pone.0154828 |
0.337 |
|
| 2016 |
Kaiser P, Regoes RR, Hardt WD. Population Dynamics Analysis of Ciprofloxacin-Persistent S. Typhimurium Cells in a Mouse Model for Salmonella Diarrhea. Methods in Molecular Biology (Clifton, N.J.). 1333: 189-203. PMID 26468110 DOI: 10.1007/978-1-4939-2854-5_16 |
0.455 |
|
| 2015 |
Kreibich S, Emmenlauer M, Fredlund J, Rämö P, Münz C, Dehio C, Enninga J, Hardt WD. Autophagy Proteins Promote Repair of Endosomal Membranes Damaged by the Salmonella Type Three Secretion System 1. Cell Host & Microbe. 18: 527-37. PMID 26567507 DOI: 10.1016/J.Chom.2015.10.015 |
0.376 |
|
| 2015 |
Hardt WD. Antibiotics: Homed to the hideout. Nature. 527: 309-10. PMID 26536107 DOI: 10.1038/Nature15647 |
0.431 |
|
| 2015 |
Schmich F, Szczurek E, Kreibich S, Dilling S, Andritschke D, Casanova A, Low SH, Eicher S, Muntwiler S, Emmenlauer M, Rämö P, Conde-Alvarez R, von Mering C, Hardt WD, Dehio C, et al. gespeR: a statistical model for deconvoluting off-target-confounded RNA interference screens. Genome Biology. 16: 220. PMID 26445817 DOI: 10.1186/S13059-015-0783-1 |
0.304 |
|
| 2015 |
Sellin ME, Maslowski KM, Maloy KJ, Hardt WD. Inflammasomes of the intestinal epithelium. Trends in Immunology. 36: 442-50. PMID 26166583 DOI: 10.1016/J.It.2015.06.002 |
0.422 |
|
| 2015 |
Kreibich S, Hardt WD. Experimental approaches to phenotypic diversity in infection. Current Opinion in Microbiology. 27: 25-36. PMID 26143306 DOI: 10.1016/J.Mib.2015.06.007 |
0.46 |
|
| 2015 |
Jennewein J, Matuszak J, Walter S, Felmy B, Gendera K, Schatz V, Nowottny M, Liebsch G, Hensel M, Hardt WD, Gerlach RG, Jantsch J. Low oxygen tensions found in Salmonella-infected gut tissue boost Salmonella replication in macrophages by impairing antimicrobial activity and augmenting Salmonella virulence. Cellular Microbiology. PMID 26104016 DOI: 10.1111/Cmi.12476 |
0.414 |
|
| 2015 |
Fougeron D, Van Maele L, Songhet P, Cayet D, Hot D, Van Rooijen N, Mollenkopf HJ, Hardt WD, Benecke AG, Sirard JC. Indirect Toll-like receptor 5-mediated activation of conventional dendritic cells promotes the mucosal adjuvant activity of flagellin in the respiratory tract. Vaccine. 33: 3331-41. PMID 26003491 DOI: 10.1016/J.Vaccine.2015.05.022 |
0.314 |
|
| 2015 |
Vishwakarma V, Sahoo SS, Das S, Ray S, Hardt WD, Suar M. Cholera toxin-B (ctxB) antigen expressing Salmonella Typhimurium polyvalent vaccine exerts protective immune response against Vibrio cholerae infection. Vaccine. 33: 1880-9. PMID 25701672 DOI: 10.1016/J.Vaccine.2015.02.014 |
0.335 |
|
| 2014 |
Rämö P, Drewek A, Arrieumerlou C, Beerenwinkel N, Ben-Tekaya H, Cardel B, Casanova A, Conde-Alvarez R, Cossart P, Csúcs G, Eicher S, Emmenlauer M, Greber U, Hardt WD, Helenius A, et al. Simultaneous analysis of large-scale RNAi screens for pathogen entry. Bmc Genomics. 15: 1162. PMID 25534632 DOI: 10.1186/1471-2164-15-1162 |
0.305 |
|
| 2014 |
Maier L, Diard M, Sellin ME, Chouffane ES, Trautwein-Weidner K, Periaswamy B, Slack E, Dolowschiak T, Stecher B, Loverdo C, Regoes RR, Hardt WD. Granulocytes impose a tight bottleneck upon the gut luminal pathogen population during Salmonella typhimurium colitis. Plos Pathogens. 10: e1004557. PMID 25522364 DOI: 10.1371/Journal.Ppat.1004557 |
0.481 |
|
| 2014 |
Maier L, Barthel M, Stecher B, Maier RJ, Gunn JS, Hardt WD. Salmonella Typhimurium strain ATCC14028 requires H2-hydrogenases for growth in the gut, but not at systemic sites. Plos One. 9: e110187. PMID 25303479 DOI: 10.1371/Journal.Pone.0110187 |
0.37 |
|
| 2014 |
Arnoldini M, Vizcarra IA, Peña-Miller R, Stocker N, Diard M, Vogel V, Beardmore RE, Hardt WD, Ackermann M. Bistable expression of virulence genes in salmonella leads to the formation of an antibiotic-tolerant subpopulation. Plos Biology. 12: e1001928. PMID 25136970 DOI: 10.1371/Journal.Pbio.1001928 |
0.409 |
|
| 2014 |
Diard M, Sellin ME, Dolowschiak T, Arnoldini M, Ackermann M, Hardt WD. Antibiotic treatment selects for cooperative virulence of Salmonella typhimurium. Current Biology : Cb. 24: 2000-5. PMID 25131673 DOI: 10.1016/J.Cub.2014.07.028 |
0.397 |
|
| 2014 |
Sellin ME, Müller AA, Felmy B, Dolowschiak T, Diard M, Tardivel A, Maslowski KM, Hardt WD. Epithelium-intrinsic NAIP/NLRC4 inflammasome drives infected enterocyte expulsion to restrict Salmonella replication in the intestinal mucosa. Cell Host & Microbe. 16: 237-48. PMID 25121751 DOI: 10.1016/J.Chom.2014.07.001 |
0.455 |
|
| 2014 |
Vonaesch P, Sellin ME, Cardini S, Singh V, Barthel M, Hardt WD. The Salmonella Typhimurium effector protein SopE transiently localizes to the early SCV and contributes to intracellular replication. Cellular Microbiology. 16: 1723-35. PMID 25052734 DOI: 10.1111/Cmi.12333 |
0.47 |
|
| 2014 |
Franceschini A, Meier R, Casanova A, Kreibich S, Daga N, Andritschke D, Dilling S, Rämö P, Emmenlauer M, Kaufmann A, Conde-Ãlvarez R, Low SH, Pelkmans L, Helenius A, Hardt WD, et al. Specific inhibition of diverse pathogens in human cells by synthetic microRNA-like oligonucleotides inferred from RNAi screens. Proceedings of the National Academy of Sciences of the United States of America. 111: 4548-53. PMID 24616511 DOI: 10.1073/Pnas.1402353111 |
0.333 |
|
| 2014 |
Kaiser P, Regoes RR, Dolowschiak T, Wotzka SY, Lengefeld J, Slack E, Grant AJ, Ackermann M, Hardt WD. Cecum lymph node dendritic cells harbor slow-growing bacteria phenotypically tolerant to antibiotic treatment. Plos Biology. 12: e1001793. PMID 24558351 DOI: 10.1371/Journal.Pbio.1001793 |
0.437 |
|
| 2013 |
Maier L, Vyas R, Cordova CD, Lindsay H, Schmidt TS, Brugiroux S, Periaswamy B, Bauer R, Sturm A, Schreiber F, von Mering C, Robinson MD, Stecher B, Hardt WD. Microbiota-derived hydrogen fuels Salmonella typhimurium invasion of the gut ecosystem. Cell Host & Microbe. 14: 641-51. PMID 24331462 DOI: 10.1016/J.Chom.2013.11.002 |
0.744 |
|
| 2013 |
Felmy B, Songhet P, Slack EM, Müller AJ, Kremer M, Van Maele L, Cayet D, Heikenwalder M, Sirard JC, Hardt WD. NADPH oxidase deficient mice develop colitis and bacteremia upon infection with normally avirulent, TTSS-1- and TTSS-2-deficient Salmonella Typhimurium. Plos One. 8: e77204. PMID 24143212 DOI: 10.1371/Journal.Pone.0077204 |
0.439 |
|
| 2013 |
Kaiser P, Slack E, Grant AJ, Hardt WD, Regoes RR. Lymph node colonization dynamics after oral Salmonella Typhimurium infection in mice. Plos Pathogens. 9: e1003532. PMID 24068916 DOI: 10.1371/Journal.Ppat.1003532 |
0.46 |
|
| 2013 |
Miki T, Hardt WD. Outer membrane permeabilization is an essential step in the killing of gram-negative bacteria by the lectin RegIIIβ. Plos One. 8: e69901. PMID 23922847 DOI: 10.1371/Journal.Pone.0069901 |
0.352 |
|
| 2013 |
Vonaesch P, Cardini S, Sellin ME, Goud B, Hardt WD, Schauer K. Quantitative insights into actin rearrangements and bacterial target site selection from Salmonella Typhimurium infection of micropatterned cells. Cellular Microbiology. 15: 1851-65. PMID 23648178 DOI: 10.1111/Cmi.12154 |
0.433 |
|
| 2013 |
Stecher B, Maier L, Hardt WD. 'Blooming' in the gut: how dysbiosis might contribute to pathogen evolution. Nature Reviews. Microbiology. 11: 277-84. PMID 23474681 DOI: 10.1038/Nrmicro2989 |
0.425 |
|
| 2013 |
Diard M, Garcia V, Maier L, Remus-Emsermann MN, Regoes RR, Ackermann M, Hardt WD. Stabilization of cooperative virulence by the expression of an avirulent phenotype. Nature. 494: 353-6. PMID 23426324 DOI: 10.1038/Nature11913 |
0.506 |
|
| 2013 |
Pati NB, Vishwakarma V, Jaiswal S, Periaswamy B, Hardt WD, Suar M. Deletion of invH gene in Salmonella enterica serovar Typhimurium limits the secretion of Sip effector proteins. Microbes and Infection / Institut Pasteur. 15: 66-73. PMID 23159244 DOI: 10.1016/J.Micinf.2012.10.014 |
0.438 |
|
| 2012 |
Periaswamy B, Maier L, Vishwakarma V, Slack E, Kremer M, Andrews-Polymenis HL, McClelland M, Grant AJ, Suar M, Hardt WD. Live attenuated S. Typhimurium vaccine with improved safety in immuno-compromised mice. Plos One. 7: e45433. PMID 23029007 DOI: 10.1371/Journal.Pone.0045433 |
0.328 |
|
| 2012 |
Miki T, Holst O, Hardt WD. The bactericidal activity of the C-type lectin RegIIIβ against Gram-negative bacteria involves binding to lipid A. The Journal of Biological Chemistry. 287: 34844-55. PMID 22896700 DOI: 10.1074/Jbc.M112.399998 |
0.346 |
|
| 2012 |
Vishwakarma V, Periaswamy B, Bhusan Pati N, Slack E, Hardt WD, Suar M. A novel phage element of Salmonella enterica serovar Enteritidis P125109 contributes to accelerated type III secretion system 2-dependent early inflammation kinetics in a mouse colitis model. Infection and Immunity. 80: 3236-46. PMID 22753379 DOI: 10.1128/Iai.00180-12 |
0.423 |
|
| 2012 |
Loetscher Y, Wieser A, Lengefeld J, Kaiser P, Schubert S, Heikenwalder M, Hardt WD, Stecher B. Salmonella transiently reside in luminal neutrophils in the inflamed gut. Plos One. 7: e34812. PMID 22493718 DOI: 10.1371/Journal.Pone.0034812 |
0.491 |
|
| 2012 |
Hitzler I, Sayi A, Kohler E, Engler DB, Koch KN, Hardt WD, Müller A. Caspase-1 has both proinflammatory and regulatory properties in Helicobacter infections, which are differentially mediated by its substrates IL-1β and IL-18. Journal of Immunology (Baltimore, Md. : 1950). 188: 3594-602. PMID 22403439 DOI: 10.4049/Jimmunol.1103212 |
0.309 |
|
| 2012 |
Endt K, Maier L, Käppeli R, Barthel M, Misselwitz B, Kremer M, Hardt WD. Peroral ciprofloxacin therapy impairs the generation of a protective immune response in a mouse model for Salmonella enterica serovar Typhimurium diarrhea, while parenteral ceftriaxone therapy does not. Antimicrobial Agents and Chemotherapy. 56: 2295-304. PMID 22354292 DOI: 10.1128/Aac.05819-11 |
0.38 |
|
| 2012 |
Müller AJ, Kaiser P, Dittmar KE, Weber TC, Haueter S, Endt K, Songhet P, Zellweger C, Kremer M, Fehling HJ, Hardt WD. Salmonella gut invasion involves TTSS-2-dependent epithelial traversal, basolateral exit, and uptake by epithelium-sampling lamina propria phagocytes. Cell Host & Microbe. 11: 19-32. PMID 22264510 DOI: 10.1016/J.Chom.2011.11.013 |
0.45 |
|
| 2012 |
Stecher B, Denzler R, Maier L, Bernet F, Sanders MJ, Pickard DJ, Barthel M, Westendorf AM, Krogfelt KA, Walker AW, Ackermann M, Dobrindt U, Thomson NR, Hardt WD. Gut inflammation can boost horizontal gene transfer between pathogenic and commensal Enterobacteriaceae. Proceedings of the National Academy of Sciences of the United States of America. 109: 1269-74. PMID 22232693 DOI: 10.1073/Pnas.1113246109 |
0.428 |
|
| 2012 |
Kaiser P, Diard M, Stecher B, Hardt WD. The streptomycin mouse model for Salmonella diarrhea: functional analysis of the microbiota, the pathogen's virulence factors, and the host's mucosal immune response. Immunological Reviews. 245: 56-83. PMID 22168414 DOI: 10.1111/J.1600-065X.2011.01070.X |
0.487 |
|
| 2011 |
Truttmann MC, Misselwitz B, Huser S, Hardt WD, Critchley DR, Dehio C. Bartonella henselae engages inside-out and outside-in signaling by integrin β1 and talin1 during invasome-mediated bacterial uptake. Journal of Cell Science. 124: 3591-602. PMID 22045736 DOI: 10.1242/Jcs.084459 |
0.361 |
|
| 2011 |
Songhet P, Barthel M, Stecher B, Müller AJ, Kremer M, Hansson GC, Hardt WD. Stromal IFN-γR-signaling modulates goblet cell function during Salmonella Typhimurium infection. Plos One. 6: e22459. PMID 21829463 DOI: 10.1371/Journal.Pone.0022459 |
0.408 |
|
| 2011 |
Sturm A, Heinemann M, Arnoldini M, Benecke A, Ackermann M, Benz M, Dormann J, Hardt WD. The cost of virulence: retarded growth of Salmonella Typhimurium cells expressing type III secretion system 1. Plos Pathogens. 7: e1002143. PMID 21829349 DOI: 10.1371/Journal.Ppat.1002143 |
0.736 |
|
| 2011 |
Kaiser P, Hardt WD. Salmonella typhimurium diarrhea: switching the mucosal epithelium from homeostasis to defense. Current Opinion in Immunology. 23: 456-63. PMID 21726991 DOI: 10.1016/J.Coi.2011.06.004 |
0.452 |
|
| 2011 |
Stelter C, Käppeli R, König C, Krah A, Hardt WD, Stecher B, Bumann D. Salmonella-induced mucosal lectin RegIIIβ kills competing gut microbiota. Plos One. 6: e20749. PMID 21694778 DOI: 10.1371/Journal.Pone.0020749 |
0.521 |
|
| 2011 |
Misselwitz B, Dilling S, Vonaesch P, Sacher R, Snijder B, Schlumberger M, Rout S, Stark M, von Mering C, Pelkmans L, Hardt WD. RNAi screen of Salmonella invasion shows role of COPI in membrane targeting of cholesterol and Cdc42. Molecular Systems Biology. 7: 474. PMID 21407211 DOI: 10.1038/Msb.2011.7 |
0.379 |
|
| 2011 |
Rühl M, Hardt WD, Sauer U. Subpopulation-specific metabolic pathway usage in mixed cultures as revealed by reporter protein-based 13C analysis. Applied and Environmental Microbiology. 77: 1816-21. PMID 21216909 DOI: 10.1128/Aem.02696-10 |
0.303 |
|
| 2011 |
Bailly-Bechet M, Benecke A, Hardt WD, Lanza V, Sturm A, Zecchina R. An externally modulated, noise-driven switch for the regulation of SPI1 in Salmonella enterica serovar Typhimurium. Journal of Mathematical Biology. 63: 637-62. PMID 21107576 DOI: 10.1007/S00285-010-0385-1 |
0.679 |
|
| 2011 |
Käppeli R, Kaiser P, Stecher B, Hardt WD. Roles of spvB and spvC in S. Typhimurium colitis via the alternative pathway. International Journal of Medical Microbiology : Ijmm. 301: 117-24. PMID 21036103 DOI: 10.1016/J.Ijmm.2010.08.017 |
0.443 |
|
| 2011 |
Stecher B, Hardt WD. Mechanisms controlling pathogen colonization of the gut. Current Opinion in Microbiology. 14: 82-91. PMID 21036098 DOI: 10.1016/J.Mib.2010.10.003 |
0.45 |
|
| 2011 |
Misselwitz B, Kreibich SK, Rout S, Stecher B, Periaswamy B, Hardt WD. Salmonella enterica serovar Typhimurium binds to HeLa cells via Fim-mediated reversible adhesion and irreversible type three secretion system 1-mediated docking. Infection and Immunity. 79: 330-41. PMID 20974826 DOI: 10.1128/Iai.00581-10 |
0.392 |
|
| 2010 |
Hardt WD. Infected cell in trouble: bystander cells ring the bell. Immunity. 33: 652-4. PMID 21094461 DOI: 10.1016/J.Immuni.2010.11.015 |
0.374 |
|
| 2010 |
Endt K, Stecher B, Chaffron S, Slack E, Tchitchek N, Benecke A, Van Maele L, Sirard JC, Mueller AJ, Heikenwalder M, Macpherson AJ, Strugnell R, von Mering C, Hardt WD. The microbiota mediates pathogen clearance from the gut lumen after non-typhoidal Salmonella diarrhea. Plos Pathogens. 6: e1001097. PMID 20844578 DOI: 10.1371/Journal.Ppat.1001097 |
0.494 |
|
| 2010 |
Hoffmann C, Galle M, Dilling S, Käppeli R, Müller AJ, Songhet P, Beyaert R, Hardt WD. In macrophages, caspase-1 activation by SopE and the type III secretion system-1 of S. typhimurium can proceed in the absence of flagellin. Plos One. 5: e12477. PMID 20814576 DOI: 10.1371/Journal.Pone.0012477 |
0.376 |
|
| 2010 |
Van Maele L, Carnoy C, Cayet D, Songhet P, Dumoutier L, Ferrero I, Janot L, Erard F, Bertout J, Leger H, Sebbane F, Benecke A, Renauld JC, Hardt WD, Ryffel B, et al. TLR5 signaling stimulates the innate production of IL-17 and IL-22 by CD3(neg)CD127+ immune cells in spleen and mucosa. Journal of Immunology (Baltimore, Md. : 1950). 185: 1177-85. PMID 20566828 DOI: 10.4049/Jimmunol.1000115 |
0.314 |
|
| 2010 |
Altmeyer M, Barthel M, Eberhard M, Rehrauer H, Hardt WD, Hottiger MO. Absence of poly(ADP-ribose) polymerase 1 delays the onset of Salmonella enterica serovar Typhimurium-induced gut inflammation. Infection and Immunity. 78: 3420-31. PMID 20515923 DOI: 10.1128/Iai.00211-10 |
0.45 |
|
| 2010 |
Bueno SM, Wozniak A, Leiva ED, Riquelme SA, Carreño LJ, Hardt WD, Riedel CA, Kalergis AM. Salmonella pathogenicity island 1 differentially modulates bacterial entry to dendritic and non-phagocytic cells. Immunology. 130: 273-87. PMID 20201987 DOI: 10.1111/J.1365-2567.2009.03233.X |
0.458 |
|
| 2010 |
Stecher B, Chaffron S, Käppeli R, Hapfelmeier S, Freedrich S, Weber TC, Kirundi J, Suar M, McCoy KD, von Mering C, Macpherson AJ, Hardt WD. Like will to like: abundances of closely related species can predict susceptibility to intestinal colonization by pathogenic and commensal bacteria. Plos Pathogens. 6: e1000711. PMID 20062525 DOI: 10.1371/Journal.Ppat.1000711 |
0.441 |
|
| 2010 |
Hänisch J, Ehinger J, Ladwein M, Rohde M, Derivery E, Bosse T, Steffen A, Bumann D, Misselwitz B, Hardt WD, Gautreau A, Stradal TE, Rottner K. Molecular dissection of Salmonella-induced membrane ruffling versus invasion. Cellular Microbiology. 12: 84-98. PMID 19732055 DOI: 10.1111/J.1462-5822.2009.01380.X |
0.361 |
|
| 2009 |
Schwan C, Stecher B, Tzivelekidis T, van Ham M, Rohde M, Hardt WD, Wehland J, Aktories K. Clostridium difficile toxin CDT induces formation of microtubule-based protrusions and increases adherence of bacteria. Plos Pathogens. 5: e1000626. PMID 19834554 DOI: 10.1371/Journal.Ppat.1000626 |
0.385 |
|
| 2009 |
Varol C, Vallon-Eberhard A, Elinav E, Aychek T, Shapira Y, Luche H, Fehling HJ, Hardt WD, Shakhar G, Jung S. Intestinal lamina propria dendritic cell subsets have different origin and functions. Immunity. 31: 502-12. PMID 19733097 DOI: 10.1016/J.Immuni.2009.06.025 |
0.355 |
|
| 2009 |
Müller AJ, Hoffmann C, Galle M, Van Den Broeke A, Heikenwalder M, Falter L, Misselwitz B, Kremer M, Beyaert R, Hardt WD. The S. Typhimurium effector SopE induces caspase-1 activation in stromal cells to initiate gut inflammation. Cell Host & Microbe. 6: 125-36. PMID 19683679 DOI: 10.1016/J.Chom.2009.07.007 |
0.408 |
|
| 2009 |
Slack E, Hapfelmeier S, Stecher B, Velykoredko Y, Stoel M, Lawson MA, Geuking MB, Beutler B, Tedder TF, Hardt WD, Bercik P, Verdu EF, McCoy KD, Macpherson AJ. Innate and adaptive immunity cooperate flexibly to maintain host-microbiota mutualism. Science (New York, N.Y.). 325: 617-20. PMID 19644121 DOI: 10.1126/Science.1172747 |
0.39 |
|
| 2009 |
Hardt WD. Journal club. An infection biologist points out an outstanding issue in mucosal immunology. Nature. 459: 893. PMID 19536224 DOI: 10.1038/459893E |
0.416 |
|
| 2009 |
Suar M, Periaswamy B, Songhet P, Misselwitz B, Müller A, Käppeli R, Kremer M, Heikenwalder M, Hardt WD. Accelerated type III secretion system 2-dependent enteropathogenesis by a Salmonella enterica serovar enteritidis PT4/6 strain. Infection and Immunity. 77: 3569-77. PMID 19528213 DOI: 10.1128/Iai.00511-09 |
0.411 |
|
| 2009 |
Ilg K, Endt K, Misselwitz B, Stecher B, Aebi M, Hardt WD. O-antigen-negative Salmonella enterica serovar Typhimurium is attenuated in intestinal colonization but elicits colitis in streptomycin-treated mice. Infection and Immunity. 77: 2568-75. PMID 19364844 DOI: 10.1128/Iai.01537-08 |
0.386 |
|
| 2009 |
Sigurdson CJ, Heikenwalder M, Manco G, Barthel M, Schwarz P, Stecher B, Krautler NJ, Hardt WD, Seifert B, MacPherson AJ, Corthesy I, Aguzzi A. Bacterial colitis increases susceptibility to oral prion disease. The Journal of Infectious Diseases. 199: 243-52. PMID 19072552 DOI: 10.1086/595791 |
0.374 |
|
| 2008 |
Kim KP, Cha JD, Jang EH, Klumpp J, Hagens S, Hardt WD, Lee KY, Loessner MJ. PEGylation of bacteriophages increases blood circulation time and reduces T-helper type 1 immune response. Microbial Biotechnology. 1: 247-57. PMID 21261844 DOI: 10.1111/J.1751-7915.2008.00028.X |
0.404 |
|
| 2008 |
Freed NE, Silander OK, Stecher B, Böhm A, Hardt WD, Ackermann M. A simple screen to identify promoters conferring high levels of phenotypic noise. Plos Genetics. 4: e1000307. PMID 19096504 DOI: 10.1371/Journal.Pgen.1000307 |
0.342 |
|
| 2008 |
Winnen B, Schlumberger MC, Sturm A, Schüpbach K, Siebenmann S, Jenny P, Hardt WD. Hierarchical effector protein transport by the Salmonella Typhimurium SPI-1 type III secretion system. Plos One. 3: e2178. PMID 18478101 DOI: 10.1371/Journal.Pone.0002178 |
0.745 |
|
| 2008 |
Stecher B, Hardt WD. The role of microbiota in infectious disease. Trends in Microbiology. 16: 107-14. PMID 18280160 DOI: 10.1016/j.tim.2007.12.008 |
0.337 |
|
| 2008 |
Hapfelmeier S, Müller AJ, Stecher B, Kaiser P, Barthel M, Endt K, Eberhard M, Robbiani R, Jacobi CA, Heikenwalder M, Kirschning C, Jung S, Stallmach T, Kremer M, Hardt WD. Microbe sampling by mucosal dendritic cells is a discrete, MyD88-independent step in DeltainvG S. Typhimurium colitis. The Journal of Experimental Medicine. 205: 437-50. PMID 18268033 DOI: 10.1084/Jem.20070633 |
0.418 |
|
| 2008 |
Stecher B, Barthel M, Schlumberger MC, Haberli L, Rabsch W, Kremer M, Hardt WD. Motility allows S. Typhimurium to benefit from the mucosal defence. Cellular Microbiology. 10: 1166-80. PMID 18241212 DOI: 10.1111/J.1462-5822.2008.01118.X |
0.452 |
|
| 2007 |
Stecher B, Robbiani R, Walker AW, Westendorf AM, Barthel M, Kremer M, Chaffron S, Macpherson AJ, Buer J, Parkhill J, Dougan G, von Mering C, Hardt WD. Salmonella enterica serovar typhimurium exploits inflammation to compete with the intestinal microbiota. Plos Biology. 5: 2177-89. PMID 17760501 DOI: 10.1371/Journal.Pbio.0050244 |
0.48 |
|
| 2007 |
Schlumberger MC, Käppeli R, Wetter M, Müller AJ, Misselwitz B, Dilling S, Kremer M, Hardt WD. Two newly identified SipA domains (F1, F2) steer effector protein localization and contribute to Salmonella host cell manipulation. Molecular Microbiology. 65: 741-60. PMID 17635190 DOI: 10.1111/J.1365-2958.2007.05823.X |
0.313 |
|
| 2007 |
Brumme S, Arnold T, Sigmarsson H, Lehmann J, Scholz HC, Hardt WD, Hensel A, Truyen U, Roesler U. Impact of Salmonella Typhimurium DT104 virulence factors invC and sseD on the onset, clinical course, colonization patterns and immune response of porcine salmonellosis. Veterinary Microbiology. 124: 274-85. PMID 17524577 DOI: 10.1016/J.Vetmic.2007.04.032 |
0.427 |
|
| 2007 |
Gerlach RG, Jäckel D, Stecher B, Wagner C, Lupas A, Hardt WD, Hensel M. Salmonella Pathogenicity Island 4 encodes a giant non-fimbrial adhesin and the cognate type 1 secretion system. Cellular Microbiology. 9: 1834-50. PMID 17388786 DOI: 10.1111/J.1462-5822.2007.00919.X |
0.461 |
|
| 2006 |
Stecher B, Paesold G, Barthel M, Kremer M, Jantsch J, Stallmach T, Heikenwalder M, Hardt WD. Chronic Salmonella enterica serovar Typhimurium-induced colitis and cholangitis in streptomycin-pretreated Nramp1+/+ mice. Infection and Immunity. 74: 5047-57. PMID 16926396 DOI: 10.1128/Iai.00072-06 |
0.376 |
|
| 2006 |
Schlumberger MC, Hardt WD. Salmonella type III secretion effectors: pulling the host cell's strings. Current Opinion in Microbiology. 9: 46-54. PMID 16406778 DOI: 10.1016/J.Mib.2005.12.006 |
0.484 |
|
| 2006 |
Suar M, Jantsch J, Hapfelmeier S, Kremer M, Stallmach T, Barrow PA, Hardt WD. Virulence of broad- and narrow-host-range Salmonella enterica serovars in the streptomycin-pretreated mouse model. Infection and Immunity. 74: 632-44. PMID 16369020 DOI: 10.1128/Iai.74.1.632-644.2006 |
0.432 |
|
| 2006 |
Ehrbar K, Winnen B, Hardt WD. The chaperone binding domain of SopE inhibits transport via flagellar and SPI-1 TTSS in the absence of InvB. Molecular Microbiology. 59: 248-64. PMID 16359332 DOI: 10.1111/J.1365-2958.2005.04931.X |
0.384 |
|
| 2005 |
Hapfelmeier S, Hardt WD. A mouse model for S. typhimurium-induced enterocolitis. Trends in Microbiology. 13: 497-503. PMID 16140013 DOI: 10.1016/j.tim.2005.08.008 |
0.334 |
|
| 2005 |
Schlumberger MC, Müller AJ, Ehrbar K, Winnen B, Duss I, Stecher B, Hardt WD. Real-time imaging of type III secretion: Salmonella SipA injection into host cells. Proceedings of the National Academy of Sciences of the United States of America. 102: 12548-53. PMID 16107539 DOI: 10.1073/Pnas.0503407102 |
0.438 |
|
| 2005 |
Schlumberger MC, Hardt WD. Triggered phagocytosis by Salmonella: bacterial molecular mimicry of RhoGTPase activation/deactivation. Current Topics in Microbiology and Immunology. 291: 29-42. PMID 15981458 |
0.386 |
|
| 2005 |
Stecher B, Macpherson AJ, Hapfelmeier S, Kremer M, Stallmach T, Hardt WD. Comparison of Salmonella enterica serovar Typhimurium colitis in germfree mice and mice pretreated with streptomycin. Infection and Immunity. 73: 3228-41. PMID 15908347 DOI: 10.1128/Iai.73.6.3228-3241.2005 |
0.372 |
|
| 2005 |
Hapfelmeier S, Stecher B, Barthel M, Kremer M, Müller AJ, Heikenwalder M, Stallmach T, Hensel M, Pfeffer K, Akira S, Hardt WD. The Salmonella pathogenicity island (SPI)-2 and SPI-1 type III secretion systems allow Salmonella serovar typhimurium to trigger colitis via MyD88-dependent and MyD88-independent mechanisms. Journal of Immunology (Baltimore, Md. : 1950). 174: 1675-85. PMID 15661931 DOI: 10.4049/Jimmunol.174.3.1675 |
0.463 |
|
| 2005 |
Panthel K, Meinel KM, Domènech VE, Retzbach H, Igwe EI, Hardt WD, Rüssmann H. Salmonella pathogenicity island 2-mediated overexpression of chimeric SspH2 proteins for simultaneous induction of antigen-specific CD4 and CD8 T cells. Infection and Immunity. 73: 334-41. PMID 15618170 DOI: 10.1128/Iai.73.1.334-341.2005 |
0.414 |
|
| 2005 |
Ehrbar K, Hardt WD. Bacteriophage-encoded type III effectors in Salmonella enterica subspecies 1 serovar Typhimurium. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases. 5: 1-9. PMID 15567133 DOI: 10.1016/J.Meegid.2004.07.004 |
0.492 |
|
| 2004 |
Brüssow H, Canchaya C, Hardt WD. Phages and the evolution of bacterial pathogens: from genomic rearrangements to lysogenic conversion. Microbiology and Molecular Biology Reviews : Mmbr. 68: 560-602, table of co. PMID 15353570 DOI: 10.1128/Mmbr.68.3.560-602.2004 |
0.407 |
|
| 2004 |
Stecher B, Hapfelmeier S, Müller C, Kremer M, Stallmach T, Hardt WD. Flagella and chemotaxis are required for efficient induction of Salmonella enterica serovar Typhimurium colitis in streptomycin-pretreated mice. Infection and Immunity. 72: 4138-50. PMID 15213159 DOI: 10.1128/Iai.72.7.4138-4150.2004 |
0.476 |
|
| 2004 |
Ehrbar K, Hapfelmeier S, Stecher B, Hardt WD. InvB is required for type III-dependent secretion of SopA in Salmonella enterica serovar Typhimurium. Journal of Bacteriology. 186: 1215-9. PMID 14762020 DOI: 10.1128/Jb.186.4.1215-1219.2004 |
0.45 |
|
| 2004 |
Hapfelmeier S, Ehrbar K, Stecher B, Barthel M, Kremer M, Hardt WD. Role of the Salmonella pathogenicity island 1 effector proteins SipA, SopB, SopE, and SopE2 in Salmonella enterica subspecies 1 serovar Typhimurium colitis in streptomycin-pretreated mice. Infection and Immunity. 72: 795-809. PMID 14742523 DOI: 10.1128/Iai.72.2.795-809.2004 |
0.443 |
|
| 2003 |
Ehrbar K, Friebel A, Miller SI, Hardt WD. Role of the Salmonella pathogenicity island 1 (SPI-1) protein InvB in type III secretion of SopE and SopE2, two Salmonella effector proteins encoded outside of SPI-1. Journal of Bacteriology. 185: 6950-67. PMID 14617659 DOI: 10.1128/Jb.185.23.6950-6967.2003 |
0.421 |
|
| 2003 |
Pelludat C, Mirold S, Hardt WD. The SopEPhi phage integrates into the ssrA gene of Salmonella enterica serovar Typhimurium A36 and is closely related to the Fels-2 prophage. Journal of Bacteriology. 185: 5182-91. PMID 12923091 DOI: 10.1128/Jb.185.17.5182-5191.2003 |
0.435 |
|
| 2003 |
Stevens MP, Friebel A, Taylor LA, Wood MW, Brown PJ, Hardt WD, Galyov EE. A Burkholderia pseudomallei type III secreted protein, BopE, facilitates bacterial invasion of epithelial cells and exhibits guanine nucleotide exchange factor activity. Journal of Bacteriology. 185: 4992-6. PMID 12897019 DOI: 10.1128/Jb.185.16.4992-4996.2003 |
0.436 |
|
| 2003 |
Aguzzi A, Hardt WD. Dangerous liaisons between a microbe and the prion protein. The Journal of Experimental Medicine. 198: 1-4. PMID 12847133 DOI: 10.1084/Jem.20030732 |
0.364 |
|
| 2003 |
Barthel M, Hapfelmeier S, Quintanilla-Martínez L, Kremer M, Rohde M, Hogardt M, Pfeffer K, Rüssmann H, Hardt WD. Pretreatment of mice with streptomycin provides a Salmonella enterica serovar Typhimurium colitis model that allows analysis of both pathogen and host. Infection and Immunity. 71: 2839-58. PMID 12704158 DOI: 10.1128/Iai.71.5.2839-2858.2003 |
0.436 |
|
| 2002 |
Buchwald G, Friebel A, Galán JE, Hardt WD, Wittinghofer A, Scheffzek K. Structural basis for the reversible activation of a Rho protein by the bacterial toxin SopE. The Embo Journal. 21: 3286-95. PMID 12093730 DOI: 10.1093/Emboj/Cdf329 |
0.379 |
|
| 2002 |
Knodler LA, Celli J, Hardt WD, Vallance BA, Yip C, Finlay BB. Salmonella effectors within a single pathogenicity island are differentially expressed and translocated by separate type III secretion systems. Molecular Microbiology. 43: 1089-103. PMID 11918798 DOI: 10.1046/J.1365-2958.2002.02820.X |
0.5 |
|
| 2002 |
Stender S, Friebel A, Linder S, Rohde M, Mirold S, Hardt W. Identification of SopE2 from Salmonella typhimurium, a conserved guanine nucleotide exchange factor for Cdc42 of the host cell. Molecular Microbiology. 36: 1206-1221. PMID 10931274 DOI: 10.1046/J.1365-2958.2000.01933.X |
0.463 |
|
| 2001 |
Ehrbar K, Mirold S, Friebel A, Stender S, Hardt W. Characterization of effector proteins translocated via the SPI1 type III secretion system of Salmonella typhimurium International Journal of Medical Microbiology. 291: 479-485. PMID 11890547 DOI: 10.1078/1438-4221-00156 |
0.488 |
|
| 2001 |
Mirold S, Rabsch W, Tschäpe H, Hardt W. Transfer of the Salmonella type III effector sopE between unrelated phage families. Journal of Molecular Biology. 312: 7-16. PMID 11545581 DOI: 10.1006/Jmbi.2001.4950 |
0.427 |
|
| 2001 |
Friebel A, Ilchmann H, Aepfelbacher M, Ehrbar K, Machleidt W, Hardt W. SopE and SopE2 from Salmonella typhimurium Activate Different Sets of RhoGTPases of the Host Cell Journal of Biological Chemistry. 276: 34035-34040. PMID 11440999 DOI: 10.1074/Jbc.M100609200 |
0.478 |
|
| 2001 |
Rüssmann H, Igwe EI, Sauer J, Hardt WD, Bubert A, Geginat G. Protection against murine listeriosis by oral vaccination with recombinant Salmonella expressing hybrid Yersinia type III proteins. Journal of Immunology (Baltimore, Md. : 1950). 167: 357-65. PMID 11418671 DOI: 10.4049/Jimmunol.167.1.357 |
0.374 |
|
| 2001 |
Mirold S, Ehrbar K, Weissmüller A, Prager R, Tschäpe H, Rüssmann H, Hardt W. Salmonella host cell invasion emerged by acquisition of a mosaic of separate genetic elements, including Salmonella pathogenicity island 1 (SPI1), SPI5, and sopE2. Journal of Bacteriology. 183: 2348-2358. PMID 11244077 DOI: 10.1128/Jb.183.7.2348-2358.2001 |
0.501 |
|
| 2000 |
Friebel A, Hardt W. Purification and biochemical activity of Salmonella exchange factor SopE. Methods in Enzymology. 325: 82-91. PMID 11036594 DOI: 10.1016/S0076-6879(00)25433-5 |
0.42 |
|
| 1999 |
Rudolph MG, Weise C, Mirold S, Hillenbrand B, Bader B, Wittinghofer A, Hardt WD. Biochemical analysis of SopE from Salmonella typhimurium, a highly efficient guanosine nucleotide exchange factor for RhoGTPases Journal of Biological Chemistry. 274: 30501-30509. PMID 10521431 DOI: 10.1074/Jbc.274.43.30501 |
0.431 |
|
| 1999 |
Mirold S, Rabsch W, Rohde M, Stender S, Tschäpe H, Rüssmann H, Igwe E, Hardt WD. Isolation of a temperate bacteriophage encoding the type III effector protein SopE from an epidemic Salmonella typhimurium strain. Proceedings of the National Academy of Sciences of the United States of America. 96: 9845-50. PMID 10449782 DOI: 10.1073/Pnas.96.17.9845 |
0.452 |
|
| 1999 |
Eichelberg K, Hardt W, Galán JE. Characterization of SprA, an AraC-like transcriptional regulator encoded within the Salmonella typhimurium pathogenicity island 1. Molecular Microbiology. 33: 139-152. PMID 10411731 DOI: 10.1046/J.1365-2958.1999.01458.X |
0.454 |
|
| 1999 |
Zhou D, Hardt W, Galán JE. Salmonella typhimurium Encodes a Putative Iron Transport System within the Centisome 63 Pathogenicity Island Infection and Immunity. 67: 1974-1981. DOI: 10.1128/Iai.67.4.1974-1981.1999 |
0.349 |
|
| 1998 |
Hardt W, Chen L, Schuebel KE, Bustelo XR, Galán JE. S. typhimurium Encodes an Activator of Rho GTPases that Induces Membrane Ruffling and Nuclear Responses in Host Cells Cell. 93: 815-826. PMID 9630225 DOI: 10.1016/S0092-8674(00)81442-7 |
0.404 |
|
| 1998 |
Hardt W, Urlaub H, Galán JE. A substrate of the centisome 63 type III protein secretion system of Salmonella typhimurium is encoded by a cryptic bacteriophage. Proceedings of the National Academy of Sciences of the United States of America. 95: 2574-2579. PMID 9482928 DOI: 10.1073/Pnas.95.5.2574 |
0.457 |
|
| 1997 |
Hardt W, Galán JE. A secreted Salmonella protein with homology to an avirulence determinant of plant pathogenic bacteria Proceedings of the National Academy of Sciences of the United States of America. 94: 9887-9892. PMID 9275221 DOI: 10.1073/Pnas.94.18.9887 |
0.451 |
|
| Show low-probability matches. |