Sebastien Lemieux, Ph.D. - Publications

Affiliations: 
2002 Université de Montréal, Montréal, Canada 
Area:
Computer Science

63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Daouda T, Dumont-Lagacé M, Feghaly A, Benslimane Y, Panes R, Courcelles M, Benhammadi M, Harrington L, Thibault P, Major F, Bengio Y, Gagnon É, Lemieux S, Perreault C. CAMAP: Artificial neural networks unveil the role of codon arrangement in modulating MHC-I peptides presentation. Plos Computational Biology. 17: e1009482. PMID 34679099 DOI: 10.1371/journal.pcbi.1009482  0.51
2020 Trofimov A, Cohen JP, Bengio Y, Perreault C, Lemieux S. Factorized embeddings learns rich and biologically meaningful embedding spaces using factorized tensor decomposition. Bioinformatics (Oxford, England). 36: i417-i426. PMID 32657403 DOI: 10.1093/Bioinformatics/Btaa488  0.311
2020 Larouche JD, Trofimov A, Hesnard L, Ehx G, Zhao Q, Vincent K, Durette C, Gendron P, Laverdure JP, Bonneil É, Côté C, Lemieux S, Thibault P, Perreault C. Widespread and tissue-specific expression of endogenous retroelements in human somatic tissues. Genome Medicine. 12: 40. PMID 32345368 DOI: 10.1186/S13073-020-00740-7  0.309
2020 Courcelles M, Durette C, Daouda T, Laverdure JP, Vincent K, Lemieux S, Perreault C, Thibault P. MAPDP: a cloud-based computational platform for immunopeptidomics analyses. Journal of Proteome Research. PMID 32108478 DOI: 10.1021/Acs.Jproteome.9B00859  0.307
2020 Zhao Q, Laverdure JP, Lanoix J, Durette C, Coté C, Bonneil E, Laumont CM, Gendron P, Vincent K, Courcelles M, Lemieux S, Millar DG, Ohashi PS, Thibault P, Perreault C. Proteogenomics uncovers a vast repertoire of shared tumor-specific antigens in ovarian cancer. Cancer Immunology Research. PMID 32047025 DOI: 10.1158/2326-6066.Cir-19-0541  0.319
2019 Dumont-Lagacé M, Daouda T, Depoërs L, Zumer J, Benslimane Y, Brochu S, Harrington L, Lemieux S, Perreault C. Qualitative Changes in Cortical Thymic Epithelial Cells Drive Postpartum Thymic Regeneration. Frontiers in Immunology. 10: 3118. PMID 32010151 DOI: 10.3389/Fimmu.2019.03118  0.305
2019 Bisaillon R, Moison C, Thiollier C, Krosl J, Bordeleau ME, Lehnertz B, Lavallée VP, MacRae T, Mayotte N, Labelle C, Boucher G, Spinella JF, Boivin I, D'Angelo G, Lavallée S, ... ... Lemieux S, et al. Genetic characterization of ABT-199 sensitivity in human AML. Leukemia. PMID 31300747 DOI: 10.1038/S41375-019-0485-X  0.33
2019 Baccelli I, Gareau Y, Lehnertz B, Gingras S, Spinella JF, Corneau S, Mayotte N, Girard S, Frechette M, Blouin-Chagnon V, Leveillé K, Boivin I, MacRae T, Krosl J, Thiollier C, ... ... Lemieux S, et al. Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia. Cancer Cell. 36: 84-99.e8. PMID 31287994 DOI: 10.1016/J.Ccell.2019.06.003  0.319
2019 Garg S, Reyes-Palomares A, He L, Bergeron A, Lavallée VP, Lemieux S, Gendron P, Rohde C, Xia J, Jagdhane P, Müller-Tidow C, Lipka DB, Imren S, Humphries RK, Waskow C, et al. Hepatic leukemia factor is a novel leukemic stem cell regulator in DNMT3A, NPM1, and FLT3-ITD triple-mutated AML. Blood. PMID 31076446 DOI: 10.1182/Blood.2018862383  0.367
2019 Moison C, Lavallée VP, Thiollier C, Lehnertz B, Boivin I, Mayotte N, Gareau Y, Fréchette M, Blouin-Chagnon V, Corneau S, Lavallée S, Lemieux S, Marinier A, Hébert J, Sauvageau G. Complex karyotype AML displays G2/M signature and hypersensitivity to PLK1 inhibition. Blood Advances. 3: 552-563. PMID 30782614 DOI: 10.1182/Bloodadvances.2018028480  0.348
2018 Laumont CM, Vincent K, Hesnard L, Audemard É, Bonneil É, Laverdure JP, Gendron P, Courcelles M, Hardy MP, Côté C, Durette C, St-Pierre C, Benhammadi M, Lanoix J, Vobecky S, ... ... Lemieux S, et al. Noncoding regions are the main source of targetable tumor-specific antigens. Science Translational Medicine. 10. PMID 30518613 DOI: 10.1126/Scitranslmed.Aau5516  0.3
2018 Marquis M, Beaubois C, Lavallée VP, Abrahamowicz M, Danieli C, Lemieux S, Ahmad I, Wei A, Ting SB, Fleming S, Schwarer A, Grimwade D, Grey W, Hills RK, Vyas P, et al. High expression of HMGA2 independently predicts poor clinical outcomes in acute myeloid leukemia. Blood Cancer Journal. 8: 68. PMID 30061630 DOI: 10.1038/S41408-018-0103-6  0.312
2018 Lavallée VP, Chagraoui J, MacRae T, Marquis M, Bonnefoy A, Krosl J, Lemieux S, Marinier A, Pabst C, Rivard GÉ, Hébert J, Sauvageau G. Transcriptomic landscape of acute promyelocytic leukemia reveals aberrant surface expression of the platelet aggregation agonist Podoplanin. Leukemia. PMID 29550835 DOI: 10.1038/S41375-018-0069-1  0.341
2018 Baccelli I, Gareau Y, Lehnertz B, Stephane G, Spinella J, Beautrait A, Corneau S, Mayotte N, Boivin I, Girard S, MacRae T, Frechette M, Leveille K, Krosl J, Thiollier C, ... ... Lemieux S, et al. Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of Mitochondrial Vulnerability in Acute Myeloid Leukemia Blood. 132: 910-910. DOI: 10.1182/Blood-2018-99-114525  0.365
2018 Moison C, Lavallee V, Thiollier C, Spinella J, Boivin I, Lemieux S, Marinier A, Hébert J, Sauvageau G. Chemogenomic Profiling of Complex Karyotype AML Reveals a Novel Susceptibility to G2/M Checkpoint Inhibition Mediated By HMGA2 Overexpression Blood. 132: 3925-3925. DOI: 10.1182/Blood-2018-99-111304  0.385
2018 Simon L, Lavallee V, Bordeleau M, Lehnertz B, MacRae T, Chagraoui J, Spinella J, Boucher G, Bertomeu T, Coulombe-Huntington J, Tyers M, Lemieux S, Marinier A, Hébert J, Sauvageau G. Chemogenomic Approach Unveils the Increased Susceptibility of RUNX1-Mutated AML to Glucocorticoids Blood. 132: 4675-4675. DOI: 10.1182/Blood-2018-99-111030  0.396
2017 Dumont-Lagacé M, Gerbe H, Daouda T, Laverdure JP, Brochu S, Lemieux S, Gagnon É, Perreault C. Detection of Quiescent Radioresistant Epithelial Progenitors in the Adult Thymus. Frontiers in Immunology. 8: 1717. PMID 29259606 DOI: 10.3389/Fimmu.2017.01717  0.335
2017 Simon L, Lavallée VP, Bordeleau ME, Krosl J, Baccelli I, Boucher G, Lehnertz B, Chagraoui J, MacRae T, Ruel R, Chantigny YA, Lemieux S, Marinier A, Hébert J, Sauvageau G. Chemogenomic landscape of RUNX1-mutated AML reveals importance of RUNX1 allele dosage in genetics and glucocorticoid sensitivity. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28855357 DOI: 10.1158/1078-0432.Ccr-17-1259  0.321
2017 Lemieux S, Sargeant T, Laperrière D, Ismail H, Boucher G, Rozendaal M, Lavallée VP, Ashton-Beaucage D, Wilhelm B, Hébert J, Hilton DJ, Mader S, Sauvageau G. MiSTIC, an integrated platform for the analysis of heterogeneity in large tumour transcriptome datasets. Nucleic Acids Research. PMID 28472340 DOI: 10.1093/Nar/Gkx338  0.344
2017 Lavallee V, Chagraoui J, Tara M, Marquis M, Arnaud B, Krosl J, Lemieux S, Rivard G, Hébert J, Sauvageau G. Podoplanin Expression in the Bleeding Complications of Acute Promyelocytic Leukemias Blood. 130: 105-105. DOI: 10.1182/Blood.V130.Suppl_1.105.105  0.315
2016 Pearson H, Daouda T, Granados DP, Durette C, Bonneil E, Courcelles M, Rodenbrock A, Laverdure JP, Côté C, Mader S, Lemieux S, Thibault P, Perreault C. MHC class I-associated peptides derive from selective regions of the human genome. The Journal of Clinical Investigation. PMID 27841757 DOI: 10.1172/Jci88590  0.32
2016 Rouette A, Trofimov A, Haberl D, Boucher G, Lavallée VP, D'Angelo G, Hébert J, Sauvageau G, Lemieux S, Perreault C. Expression of immunoproteasome genes is regulated by cell-intrinsic and -extrinsic factors in human cancers. Scientific Reports. 6: 34019. PMID 27659694 DOI: 10.1038/Srep34019  0.339
2016 Lavallée VP, Krosl J, Lemieux S, Boucher G, Gendron P, Pabst C, Boivin I, Marinier A, Guidos CJ, Meloche S, Hébert J, Sauvageau G. Chemo-genomic interrogation of CEBPA mutated AML reveals recurrent CSF3R mutations and subgroup sensitivity to JAK inhibitors. Blood. PMID 27034432 DOI: 10.1182/Blood-2016-03-705053  0.33
2016 Lavallée VP, Lemieux S, Boucher G, Gendron P, Boivin I, Armstrong RN, Sauvageau G, Hébert J. RNA-sequencing analysis of core binding factor AML identifies recurrent ZBTB7A mutations and defines RUNX1-CBFA2T3 fusion signature. Blood. PMID 26968532 DOI: 10.1182/Blood-2016-03-703868  0.339
2016 Granados DP, Rodenbrock A, Laverdure JP, Côté C, Caron-Lizotte O, Carli C, Pearson H, Janelle V, Durette C, Bonneil E, Roy DC, Delisle JS, Lemieux S, Thibault P, Perreault C. Proteogenomic-based discovery of minor histocompatibility antigens with suitable features for immunotherapy of hematologic cancers. Leukemia. PMID 26857467 DOI: 10.1038/Leu.2016.22  0.314
2016 Pabst C, Bergeron A, Lavallée VP, Yeh J, Gendron P, Norddahl GL, Krosl J, Boivin I, Deneault E, Simard J, Imren S, Boucher G, Eppert K, Herold T, Bohlander SK, ... ... Lemieux S, et al. GPR56 identifies primary human acute myeloid leukemia cells with high repopulating potential in vivo. Blood. PMID 26834243 DOI: 10.1182/Blood-2015-11-683649  0.332
2016 Lavallée V, Thiollier C, Moison C, Bordeleau M, Boivin I, Boucher G, Gendron P, Lemieux S, Marinier A, Hébert J, Sauvageau G. Chemo-Transcriptomic Analysis of Complex Karyotype AML Reveals Increased Expression of Cell Cycle Components and Exquisite Dependency on Polo-like Kinase 1 Blood. 128: 769-769. DOI: 10.1182/Blood.V128.22.769.769  0.376
2016 Lavallée V, Marquis M, Bordeleau M, Chagraoui J, MacRae T, Boivin I, Boucher G, Gendron P, Lemieux S, Bonnefoy A, Rivard GE, Hébert J, Sauvageau G. Transcriptional Landscape of APL Identifies Aberrant Podoplanin Expression As a Defining Feature and Missing Link for the Bleeding Disorder of This Disease Blood. 128: 1075-1075. DOI: 10.1182/Blood.V128.22.1075.1075  0.353
2015 Lavallée VP, Baccelli I, Krosl J, Wilhelm B, Barabé F, Gendron P, Boucher G, Lemieux S, Marinier A, Meloche S, Hébert J, Sauvageau G. The transcriptomic landscape and directed chemical interrogation of MLL-rearranged acute myeloid leukemias. Nature Genetics. 47: 1030-7. PMID 26237430 DOI: 10.1038/Ng.3371  0.343
2015 Bonneau E, Girard N, Lemieux S, Legault P. The NMR structure of the II-III-VI three-way junction from the Neurospora VS ribozyme reveals a critical tertiary interaction and provides new insights into the global ribozyme structure. Rna (New York, N.Y.). 21: 1621-32. PMID 26124200 DOI: 10.1261/Rna.052076.115  0.302
2015 St-Pierre C, Trofimov A, Brochu S, Lemieux S, Perreault C. Differential Features of AIRE-Induced and AIRE-Independent Promiscuous Gene Expression in Thymic Epithelial Cells. Journal of Immunology (Baltimore, Md. : 1950). 195: 498-506. PMID 26034170 DOI: 10.4049/Jimmunol.1500558  0.302
2015 Lavallée VP, Gendron P, Lemieux S, D'Angelo G, Hébert J, Sauvageau G. EVI1-rearranged acute myeloid leukemias are characterized by distinct molecular alterations. Blood. 125: 140-3. PMID 25331116 DOI: 10.1182/Blood-2014-07-591529  0.349
2015 Lavallée V, Gendron P, Boucher G, Lemieux S, Armstrong RN, Boivin I, Sauvageau G, Hébert J. Mutational and Transcriptomic Landscape of AML with Core-Binding Factor Rearrangements Blood. 126: 802-802. DOI: 10.1182/Blood.V126.23.802.802  0.353
2015 Maiga A, Lemieux S, Pabst C, Lavallée V, Bouvier M, Sauvageau G, Hébert J. Transcriptome Analysis Reveals That G Protein-Coupled Receptors Are Potential Diagnostic Markers or Therapeutic Targets in Acute Myeloid Leukemia Blood. 126: 3855-3855. DOI: 10.1182/Blood.V126.23.3855.3855  0.347
2014 Gerby B, Tremblay CS, Tremblay M, Rojas-Sutterlin S, Herblot S, Hébert J, Sauvageau G, Lemieux S, Lécuyer E, Veiga DF, Hoang T. SCL, LMO1 and Notch1 reprogram thymocytes into self-renewing cells. Plos Genetics. 10: e1004768. PMID 25522233 DOI: 10.1371/Journal.Pgen.1004768  0.31
2014 Pabst C, Krosl J, Fares I, Boucher G, Ruel R, Marinier A, Lemieux S, Hébert J, Sauvageau G. Identification of small molecules that support human leukemia stem cell activity ex vivo. Nature Methods. 11: 436-42. PMID 24562423 DOI: 10.1038/Nmeth.2847  0.319
2014 Celton M, Forest A, Gosse G, Lemieux S, Hebert J, Sauvageau G, Wilhelm BT. Epigenetic regulation of GATA2 and its impact on normal karyotype acute myeloid leukemia. Leukemia. 28: 1617-26. PMID 24514424 DOI: 10.1038/Leu.2014.67  0.359
2014 Lehnertz B, Boucher G, Mallard W, Gendron P, Hebert J, Lemieux S, Rinn J, Sauvageau G. Long non-coding RNA expression in normal and leukemic human blood samples: Towards the identification of novel biomarkers and hematopoietic regulators Experimental Hematology. 42: S45. DOI: 10.1016/J.Exphem.2014.07.166  0.311
2013 Macrae T, Sargeant T, Lemieux S, Hébert J, Deneault E, Sauvageau G. RNA-Seq reveals spliceosome and proteasome genes as most consistent transcripts in human cancer cells. Plos One. 8: e72884. PMID 24069164 DOI: 10.1371/Journal.Pone.0072884  0.353
2013 Lacombe J, Krosl G, Tremblay M, Gerby B, Martin R, Aplan PD, Lemieux S, Hoang T. Genetic interaction between Kit and Scl. Blood. 122: 1150-61. PMID 23836559 DOI: 10.1182/Blood-2011-01-331819  0.331
2013 Courcelles M, Frémin C, Voisin L, Lemieux S, Meloche S, Thibault P. Phosphoproteome dynamics reveal novel ERK1/2 MAP kinase substrates with broad spectrum of functions. Molecular Systems Biology. 9: 669. PMID 23712012 DOI: 10.1038/Msb.2013.25  0.3
2013 St-Pierre C, Brochu S, Vanegas JR, Dumont-Lagacé M, Lemieux S, Perreault C. Transcriptome sequencing of neonatal thymic epithelial cells. Scientific Reports. 3: 1860. PMID 23681267 DOI: 10.1038/Srep01860  0.348
2013 Sauvageau G, Pabst C, Lemieux S, Hébert J, Krosl J. Novel Targeting Strategies for Leukemia-Initiating Cells in Myeloid Neoplasms Blood. 122: SCI-27-SCI-27. DOI: 10.1182/Blood.V122.21.Sci-27.Sci-27  0.326
2013 Lavallée V, Gendron P, Boucher G, Arteau M, Wilhelm BT, Lemieux S, Hébert J, Sauvageau G. NGS-Based Detection Of Multiple RAS-Mutated Clones In MLL-Rearranged Leukemias Suggests Strong Oncogenic Collaboration Blood. 122: 744-744. DOI: 10.1182/Blood.V122.21.744.744  0.319
2012 Granados DP, Yahyaoui W, Laumont CM, Daouda T, Muratore-Schroeder TL, Côté C, Laverdure JP, Lemieux S, Thibault P, Perreault C. MHC I-associated peptides preferentially derive from transcripts bearing miRNA response elements. Blood. 119: e181-91. PMID 22438248 DOI: 10.1182/Blood-2012-02-412593  0.309
2012 Simon C, Chagraoui J, Krosl J, Gendron P, Wilhelm B, Lemieux S, Boucher G, Chagnon P, Drouin S, Lambert R, Rondeau C, Bilodeau A, Lavallée S, Sauvageau M, Hébert J, et al. A key role for EZH2 and associated genes in mouse and human adult T-cell acute leukemia. Genes & Development. 26: 651-6. PMID 22431509 DOI: 10.1101/Gad.186411.111  0.329
2012 Lacroix-Labonté J, Girard N, Lemieux S, Legault P. Helix-length compensation studies reveal the adaptability of the VS ribozyme architecture. Nucleic Acids Research. 40: 2284-93. PMID 22086962 DOI: 10.1093/Nar/Gkr1018  0.35
2010 de Verteuil D, Muratore-Schroeder TL, Granados DP, Fortier MH, Hardy MP, Bramoullé A, Caron E, Vincent K, Mader S, Lemieux S, Thibault P, Perreault C. Deletion of immunoproteasome subunits imprints on the transcriptome and has a broad impact on peptides presented by major histocompatibility complex I molecules. Molecular & Cellular Proteomics : McP. 9: 2034-47. PMID 20484733 DOI: 10.1074/Mcp.M900566-Mcp200  0.328
2009 Trunk K, Gendron P, Nantel A, Lemieux S, Roemer T, Raymond M. Depletion of the cullin Cdc53p induces morphogenetic changes in Candida albicans. Eukaryotic Cell. 8: 756-67. PMID 19270112 DOI: 10.1128/Ec.00332-08  0.323
2009 Devkota B, Petrov AS, Lemieux S, Boz MB, Tang L, Schneemann A, Johnson JE, Harvey SC. Structural and electrostatic characterization of pariacoto virus: implications for viral assembly. Biopolymers. 91: 530-8. PMID 19226622 DOI: 10.1002/Bip.21168  0.308
2008 Fedorova ND, Khaldi N, Joardar VS, Maiti R, Amedeo P, Anderson MJ, Crabtree J, Silva JC, Badger JH, Albarraq A, Angiuoli S, Bussey H, Bowyer P, Cotty PJ, Dyer PS, ... ... Lemieux S, et al. Genomic islands in the pathogenic filamentous fungus Aspergillus fumigatus. Plos Genetics. 4: e1000046. PMID 18404212 DOI: 10.1371/Journal.Pgen.1000046  0.308
2008 Znaidi S, Weber S, Al-Abdin OZ, Bomme P, Saidane S, Drouin S, Lemieux S, De Deken X, Robert F, Raymond M. Genomewide location analysis of Candida albicans Upc2p, a regulator of sterol metabolism and azole drug resistance. Eukaryotic Cell. 7: 836-47. PMID 18390649 DOI: 10.1128/Ec.00070-08  0.325
2008 Bouchard P, Lacroix-Labonté J, Desjardins G, Lampron P, Lisi V, Lemieux S, Major F, Legault P. Role of SLV in SLI substrate recognition by the Neurospora VS ribozyme. Rna (New York, N.Y.). 14: 736-48. PMID 18314503 DOI: 10.1261/Rna.824308  0.563
2008 Sauvageau M, Miller M, Lemieux S, Lessard J, Hébert J, Sauvageau G. Quantitative expression profiling guided by common retroviral insertion sites reveals novel and cell type specific cancer genes in leukemia. Blood. 111: 790-9. PMID 17906077 DOI: 10.1182/Blood-2007-07-098236  0.335
2007 Hu W, Sillaots S, Lemieux S, Davison J, Kauffman S, Breton A, Linteau A, Xin C, Bowman J, Becker J, Jiang B, Roemer T. Essential gene identification and drug target prioritization in Aspergillus fumigatus. Plos Pathogens. 3: e24. PMID 17352532 DOI: 10.1371/Journal.Ppat.0030024  0.317
2007 Tremblay M, Herblot S, Todorova M, Lisi V, Major F, Lemieux S, Hoang T. Identification of SCL and LMO Oncogenes as Transcriptional Repressors of HEB/E2A in the Thymus through Functional Genomic/Genetic Approaches. Blood. 110: 2649-2649. DOI: 10.1182/Blood.V110.11.2649.2649  0.597
2006 Lemieux S, Major F. Automated extraction and classification of RNA tertiary structure cyclic motifs. Nucleic Acids Research. 34: 2340-6. PMID 16679452 DOI: 10.1093/Nar/Gkl120  0.573
2003 Roemer T, Jiang B, Davison J, Ketela T, Veillette K, Breton A, Tandia F, Linteau A, Sillaots S, Marta C, Martel N, Veronneau S, Lemieux S, Kauffman S, Becker J, et al. Large-scale essential gene identification in Candida albicans and applications to antifungal drug discovery. Molecular Microbiology. 50: 167-81. PMID 14507372 DOI: 10.1046/J.1365-2958.2003.03697.X  0.31
2002 Lemieux S, Major F. RNA canonical and non-canonical base pairing types: a recognition method and complete repertoire. Nucleic Acids Research. 30: 4250-63. PMID 12364604 DOI: 10.1093/Nar/Gkf540  0.558
2001 Gendron P, Lemieux S, Major F. Quantitative analysis of nucleic acid three-dimensional structures. Journal of Molecular Biology. 308: 919-36. PMID 11352582 DOI: 10.1006/Jmbi.2001.4626  0.58
1998 Zhang F, Lemieux S, Wu X, St-Arnaud D, McMurray CT, Major F, Anderson D. Function of hexameric RNA in packaging of bacteriophage phi 29 DNA in vitro. Molecular Cell. 2: 141-7. PMID 9702201 DOI: 10.1016/S1097-2765(00)80123-9  0.569
1998 Lemieux S, Chartrand P, Cedergren R, Major F. Modeling active RNA structures using the intersection of conformational space: application to the lead-activated ribozyme. Rna (New York, N.Y.). 4: 739-49. PMID 9671048 DOI: 10.1017/S1355838298971266  0.577
1998 Major F, Lemieux S, Ftouhi A. Computer RNA Three-Dimensional Modeling from Low-Resolution Data and Multiple-Sequence Information Acs Symposium Series. 682: 394-404.  0.519
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