Jill P. Mesirov - Publications

Affiliations: 
Boston University, Boston, MA, United States 
Area:
Bioinformatics Biology, Computer Science

122 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Ma JY, Ting S, Tam B, Pham T, Reich M, Mesirov J, Tamayo P, Kim W. Deciphering the Functional Roles of Individual Cancer Alleles Across Comprehensive Cancer Genomic Studies. Biorxiv : the Preprint Server For Biology. PMID 38014215 DOI: 10.1101/2023.11.14.567106  0.319
2023 Castanza AS, Recla JM, Eby D, Thorvaldsdóttir H, Bult CJ, Mesirov JP. Extending support for mouse data in the Molecular Signatures Database (MSigDB). Nature Methods. PMID 37704782 DOI: 10.1038/s41592-023-02014-7  0.738
2021 Benitez JA, Finlay D, Castanza A, Parisian AD, Ma J, Longobardi C, Campos A, Vadla R, Izurieta A, Scerra G, Koga T, Long T, Chavez L, Mesirov JP, Vuori K, et al. Pten Deficiency Leads To Proteasome Addiction, A Novel Vulnerability In Glioblastoma. Neuro-Oncology. PMID 33428749 DOI: 10.1093/neuonc/noab001  0.729
2020 Yeerna H, Briggs B, Rusert J, Chavez L, Mesirov J, Wechsler-Reya R, Tamayo P. Abstract B21: Childhood Cancer Molecular Map (C2M2) to define medulloblastoma heterogeneity and predict treatment response Cancer Research. 80. DOI: 10.1158/1538-7445.Pedca19-B21  0.367
2020 Chapman OS, Ehrenberger T, Archer TC, Gold MP, Mundt F, Adam M, Mah CK, Krug K, Chandran S, Dixon JR, Pomeroy SL, Fraenkel E, Mesirov JP, Chavez L. Abstract 447: Integrated omics modeling of transcriptional regulation in medulloblastoma subtypes Cancer Research. 80: 447-447. DOI: 10.1158/1538-7445.Am2020-447  0.375
2019 Banerjee S, Wei T, Wang J, Lee JJ, Gutierrez HL, Chapman O, Wiley SE, Mayfield JE, Tandon V, Juarez EF, Chavez L, Liang R, Sah RL, Costello C, Mesirov JP, et al. Inhibition of dual-specificity tyrosine phosphorylation-regulated kinase 2 perturbs 26S proteasome-addicted neoplastic progression. Proceedings of the National Academy of Sciences of the United States of America. PMID 31754034 DOI: 10.1073/Pnas.1912033116  0.308
2019 Okonechnikov K, Hübner J, Chapman O, Chakraborty A, Bump R, Chandran S, Kraft K, Acuna Hidalgo R, Mundlos S, Coufal N, Levy M, Crawford J, Ay F, Mesirov J, Pajtler K, et al. GENE-15. TARGETING OF EPENDYMOMA AS INFORMED BY ONCOGENIC 3D GENOME ORGANIZATION Neuro-Oncology. 21: vi100-vi100. DOI: 10.1093/Neuonc/Noz175.417  0.396
2019 Okonechnikov K, Hübner J, Kraft K, Hidalgo RA, Bump R, Chandran S, Mundlos S, Mesirov J, Pajtler K, Dixon J, Pfister S, Kool M, Chavez L. GENE-02. CHROMOSOME CONFORMATION ANALYSIS OF EPENDYMOMA IDENTIFIES PUTATIVE TUMOR DEPENDENCY GENES ACTIVATED BY DISTAL ONCOGENIC ENHANCERS Neuro-Oncology. 21: ii80-ii81. DOI: 10.1093/Neuonc/Noz036.073  0.337
2018 Mah CK, Wenzel AT, Juarez EF, Tabor T, Reich MM, Mesirov JP. An accessible, interactive GenePattern Notebook for analysis and exploration of single-cell transcriptomic data. F1000research. 7: 1306. PMID 31316748 DOI: 10.12688/F1000Research.15830.2  0.347
2018 Krug K, Mertins P, Zhang B, Hornbeck P, Raju R, Ahmad R, Szucs M, Mundt F, Forestier D, Jane-Valbuena J, Keshishian H, Gillette MA, Tamayo P, Mesirov JP, Jaffe JD, et al. A curated resource for phosphosite-specific signature analysis. Molecular & Cellular Proteomics : McP. PMID 30563849 DOI: 10.1074/Mcp.Tir118.000943  0.372
2018 Archer TC, Ehrenberger T, Mundt F, Gold MP, Krug K, Mah CK, Mahoney EL, Daniel CJ, LeNail A, Ramamoorthy D, Mertins P, Mani DR, Zhang H, Gillette MA, Clauser K, ... ... Mesirov JP, et al. Proteomics, Post-translational Modifications, and Integrative Analyses Reveal Molecular Heterogeneity within Medulloblastoma Subgroups. Cancer Cell. 34: 396-410.e8. PMID 30205044 DOI: 10.1016/J.Ccell.2018.08.004  0.339
2018 Li T, Kim A, Rosenbluh J, Horn H, Greenfeld L, An D, Zimmer A, Liberzon A, Bistline J, Natoli T, Li Y, Tsherniak A, Narayan R, Subramanian A, Liefeld T, ... ... Mesirov J, et al. GeNets: a unified web platform for network-based genomic analyses. Nature Methods. PMID 29915188 DOI: 10.1038/S41592-018-0039-6  0.546
2018 Robinson JT, Turner D, Durand NC, Thorvaldsdóttir H, Mesirov JP, Aiden EL. Juicebox.js Provides a Cloud-Based Visualization System for Hi-C Data. Cell Systems. PMID 29428417 DOI: 10.1016/J.Cels.2018.01.001  0.319
2018 Carlin DE, Kim F, Ideker T, Mesirov JP. A unified GenomeSpace recipe to identify essential genes and associated subnetworks from Genome-Scale CRISPR-Cas9 knockout screens F1000research. 7: 1636. DOI: 10.12688/F1000Research.16290.1  0.301
2018 Yeerna H, Kim W, Hahn WC, Mesirov J, Tamayo P. Abstract 1416: Pan-cancer mutual vulnerability and viability Cancer Research. 78: 1416-1416. DOI: 10.1158/1538-7445.Am2018-1416  0.426
2017 Carlin D, Kosnicki K, Garamszegi S, Ideker T, Thorvaldsdóttir H, Reich M, Mesirov J. A multi-tool recipe to identify regions of protein-DNA binding and their influence on associated gene expression. F1000research. 6: 784. PMID 29487738 DOI: 10.12688/F1000Research.11616.1  0.343
2017 Hachigian LJ, Carmona V, Fenster RJ, Kulicke R, Heilbut A, Sittler A, Pereira de Almeida L, Mesirov JP, Gao F, Kolaczyk ED, Heiman M. Control of Huntington's Disease-Associated Phenotypes by the Striatum-Enriched Transcription Factor Foxp2. Cell Reports. 21: 2688-2695. PMID 29212017 DOI: 10.1016/J.Celrep.2017.11.018  0.302
2017 Robinson JT, Thorvaldsdóttir H, Wenger AM, Zehir A, Mesirov JP. Variant Review with the Integrative Genomics Viewer. Cancer Research. 77: e31-e34. PMID 29092934 DOI: 10.1158/0008-5472.Can-17-0337  0.388
2017 Kim JW, Abudayyeh OO, Yeerna H, Yeang CH, Stewart M, Jenkins RW, Kitajima S, Konieczkowski DJ, Medetgul-Ernar K, Cavazos T, Mah C, Ting S, Van Allen EM, Cohen O, Mcdermott J, ... ... Mesirov JP, et al. Decomposing Oncogenic Transcriptional Signatures to Generate Maps of Divergent Cellular States. Cell Systems. 5: 105-118.e9. PMID 28837809 DOI: 10.1016/J.Cels.2017.08.002  0.584
2017 Reich M, Tabor T, Liefeld T, Thorvaldsdóttir H, Hill B, Tamayo P, Mesirov JP. The GenePattern Notebook Environment. Cell Systems. PMID 28822753 DOI: 10.1016/J.Cels.2017.07.003  0.306
2017 Huang FW, Mosquera JM, Garofalo A, Oh C, Baco M, Amin-Mansour A, Rabasha B, Bahl S, Mullane SA, Robinson BD, Aldubayan S, Khani F, Karir B, Kim E, Chimene-Weiss J, ... ... Mesirov J, et al. Exome Sequencing of African-American Prostate Cancer Reveals Loss-of-Function ERF Mutations. Cancer Discovery. PMID 28515055 DOI: 10.1158/2159-8290.Cd-16-0960  0.316
2017 Boulay G, Awad ME, Riggi N, Archer TC, Iyer S, Boonseng WE, Rossetti NE, Naigles B, Rengarajan S, Volorio A, Kim JC, Mesirov JP, Tamayo P, Pomeroy SL, Aryee MJ, et al. OTX2 Activity at Distal Regulatory Elements Shapes the Chromatin Landscape of Group 3 Medulloblastoma. Cancer Discovery. PMID 28213356 DOI: 10.1158/2159-8290.Cd-16-0844  0.351
2017 Liefeld T, Ocana M, Reich M, Thorvaldsdottir H, Mesirov JP. GenomeSpace: integrating cloud storage providers for genomic analysis F1000research. 6. DOI: 10.7490/F1000Research.1114640.1  0.344
2017 Kim JW, Hahn WC, Mesirov J, Tamayo P. Abstract A09: Decomposing Oncogenic Transcriptional Signatures to Generate Maps of RAS/MAPK Cellular States Molecular Cancer Therapeutics. 16. DOI: 10.1158/1538-8514.Synthleth-A09  0.367
2017 Kim WJ, Hahn WC, Mesirov J, Tamayo P. Abstract 3035: Decomposing oncogenic transcriptional signatures to generate maps of divergent cellular states Cancer Research. 77: 3035-3035. DOI: 10.1158/1538-7445.Am2017-3035  0.374
2017 Yeerna H, Rangan R, Aguirre A, Kim W, Vazquez F, Weir B, Ghandi M, Tsherniak A, Boehm J, Hahn W, Mesirov J, Tamayo P. Abstract 1555: Pan-cancer patterns of synthetic lethality: statistical modeling of gene dependency profiles Cancer Research. 77: 1555-1555. DOI: 10.1158/1538-7445.Am2017-1555  0.406
2016 Spira A, Disis ML, Schiller JT, Vilar E, Rebbeck TR, Bejar R, Ideker T, Arts J, Yurgelun MB, Mesirov JP, Rao A, Garber J, Jaffee EM, Lippman SM. Leveraging premalignant biology for immune-based cancer prevention. Proceedings of the National Academy of Sciences of the United States of America. PMID 27638202 DOI: 10.1073/Pnas.1608077113  0.353
2016 D'Antonio M, Tamayo P, Mesirov JP, Frazer KA. Kataegis Expression Signature in Breast Cancer Is Associated with Late Onset, Better Prognosis, and Higher HER2 Levels. Cell Reports. PMID 27373164 DOI: 10.1016/J.Celrep.2016.06.026  0.37
2016 Kim JW, Botvinnik OB, Abudayyeh O, Birger C, Rosenbluh J, Shrestha Y, Abazeed ME, Hammerman PS, DiCara D, Konieczkowski DJ, Johannessen CM, Liberzon A, Alizad-Rahvar AR, Alexe G, Aguirre A, ... ... Mesirov JP, et al. Characterizing genomic alterations in cancer by complementary functional associations. Nature Biotechnology. PMID 27088724 DOI: 10.1038/Nbt.3527  0.427
2016 Hanaford AR, Archer TC, Price A, Kahlert UD, Maciaczyk J, Nikkhah G, Kim JW, Ehrenberger T, Clemons PA, Dančík V, Seashore-Ludlow B, Viswanathan V, Stewart ML, Rees M, Shamji AF, ... ... Mesirov JP, et al. DiSCoVERing innovative therapies for rare tumors: combining genetically accurate disease models with in silico analysis to identify novel therapeutic targets. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27012813 DOI: 10.1158/1078-0432.Ccr-15-3011  0.315
2016 Godec J, Tan Y, Liberzon A, Tamayo P, Bhattacharya S, Butte AJ, Mesirov JP, Haining WN. Compendium of Immune Signatures Identifies Conserved and Species-Specific Biology in Response to Inflammation. Immunity. PMID 26795250 DOI: 10.1016/J.Immuni.2015.12.006  0.364
2016 Qu K, Garamszegi S, Wu F, Thorvaldsdottir H, Liefeld T, Ocana M, Borges-Rivera D, Pochet N, Robinson JT, Demchak B, Hull T, Ben-Artzi G, Blankenberg D, Barber GP, Lee BT, ... ... Mesirov JP, et al. Integrative genomic analysis by interoperation of bioinformatics tools in GenomeSpace. Nature Methods. PMID 26780094 DOI: 10.1038/Nmeth.3732  0.337
2016 Tamayo P, Steinhardt G, Liberzon A, Mesirov JP. The limitations of simple gene set enrichment analysis assuming gene independence. Statistical Methods in Medical Research. 25: 472-87. PMID 23070592 DOI: 10.1177/0962280212460441  0.343
2016 Reich M, Tabor T, Carr P, Eby D, Thorvaldsdottir H, Hill B, Liefeld T, Tamayo P, Mesirov J. GenePattern Notebooks: An integrative analytical environment for genomic research F1000research. 5. DOI: 10.7490/F1000Research.1112770.1  0.315
2016 Reich MM, Tabor T, Liefeld JT, Carr P, Hill B, Nazaire M, Eby D, Thorvaldsdottir H, Tamayo P, Mesirov JP. Abstract 5273: GenePattern Notebooks: an integrative analytical environment for cancer research Cancer Research. 76: 5273-5273. DOI: 10.1158/1538-7445.Am2016-5273  0.383
2016 Hanaford AR, Archer TC, Price A, Kahlert U, Maciaczyk J, Guido N, Kim W, Ehrenberger T, Clemons P, Dancik V, Seashore-Ludlow B, Viswanathan V, Stewart M, Rees M, Shamji A, ... ... Mesirov J, et al. Abstract 2476: DiSCoVERing innovative therapies for rare tumors: Combining genetically accurate disease models with advanced in silico analysis to identify novel therapeutic targets Cancer Research. 76: 2476-2476. DOI: 10.1158/1538-7445.Am2016-2476  0.307
2016 Rusert J, Garancher A, Brabetz S, Udaka Y, Jensen J, Esparza L, Seker-Cin H, Qi L, Kogiso M, Schubert S, Milde T, Cho Y, Li X, Olson J, Tamayo P, ... ... Mesirov J, et al. PDTB-23. CHEMI-GENOMIC ANALYSIS OF PATIENT-DERIVED XENOGRAFTS TO IDENTIFY PERSONALIZED THERAPIES FOR MEDULLOBLASTOMA Neuro-Oncology. 18: vi154-vi155. DOI: 10.1093/Neuonc/Now212.642  0.33
2015 Liberzon A, Birger C, Thorvaldsdóttir H, Ghandi M, Mesirov JP, Tamayo P. The Molecular Signatures Database (MSigDB) hallmark gene set collection. Cell Systems. 1: 417-425. PMID 26771021 DOI: 10.1016/J.Cels.2015.12.004  0.371
2015 Zhu X, Girardo D, Govek EE, John K, Mellén M, Tamayo P, Mesirov JP, Hatten ME. Role of Tet1/3 Genes and Chromatin Remodeling Genes in Cerebellar Circuit Formation. Neuron. PMID 26711116 DOI: 10.1016/J.Neuron.2015.11.030  0.315
2015 Tan Y, Wu F, Tamayo P, Haining WN, Mesirov JP. Constellation Map: Downstream visualization and interpretation of gene set enrichment results. F1000research. 4: 167. PMID 26594333 DOI: 10.12688/F1000Research.6644.1  0.34
2015 Papageorgiou A, Rapley J, Mesirov JP, Tamayo P, Avruch J. A genome-wide siRNA screen in mammalian cells for regulators of S6 phosphorylation. Plos One. 10: e0116096. PMID 25790369 DOI: 10.1371/Journal.Pone.0116096  0.377
2015 Thorvaldsdóttir H, Robinson JT, Turner D, Mesirov JP. A genomic data viewer for iPad. Genome Biology. 16: 46. PMID 25723152 DOI: 10.1186/S13059-015-0595-3  0.359
2015 Johannessen C, Konieczkowski D, Abudayyeh O, Kim JW, Cooper Z, Piris A, Frederick D, Barzily-Rokni M, Straussman R, Haq R, Fisher D, Mesirov J, Hahn W, Flaherty K, Wargo J, et al. Abstract PR04: A melanoma transcriptional state distinction influences sensitivity to MAPK pathway inhibitors Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Pms14-Pr04  0.305
2015 Papageorgiou A, Tamayo P, Mesirov J, Avruch J, Rapley J. Abstract A30: A genome-wide siRNA screen in mammalian cells for regulators of S6 phosphorylation Molecular Cancer Therapeutics. 14. DOI: 10.1158/1538-8514.Pi3K14-A30  0.381
2014 Cowley GS, Weir BA, Vazquez F, Tamayo P, Scott JA, Rusin S, East-Seletsky A, Ali LD, Gerath WF, Pantel SE, Lizotte PH, Jiang G, Hsiao J, Tsherniak A, Dwinell E, ... ... Mesirov JP, et al. Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies. Scientific Data. 1: 140035. PMID 25984343 DOI: 10.1038/Sdata.2014.35  0.364
2014 Cowley GS, Weir BA, Vazquez F, Tamayo P, Scott JA, Rusin S, East-Seletsky A, Ali LD, Gerath WF, Pantel SE, Lizotte PH, Jiang G, Hsiao J, Tsherniak A, Dwinell E, ... ... Mesirov JP, et al. Erratum: Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies. Scientific Data. 1: 140044. PMID 25982629 DOI: 10.1038/Sdata.2014.44  0.347
2014 Barbie TU, Alexe G, Aref AR, Li S, Zhu Z, Zhang X, Imamura Y, Thai TC, Huang Y, Bowden M, Herndon J, Cohoon TJ, Fleming T, Tamayo P, Mesirov JP, et al. Targeting an IKBKE cytokine network impairs triple-negative breast cancer growth. The Journal of Clinical Investigation. 124: 5411-23. PMID 25365225 DOI: 10.1172/Jci75661  0.303
2014 Demchak B, Hull T, Reich M, Liefeld T, Smoot M, Ideker T, Mesirov JP. Cytoscape: the network visualization tool for GenomeSpace workflows. F1000research. 3: 151. PMID 25165537 DOI: 10.12688/F1000Research.4492.2  0.315
2014 Reich MM, Liefeld J, Ocana M, Jang D, Robinson J, Carr P, Hill B, Tabor T, Thorvaldsdottir H, Regev A, Mesirov JP. Abstract 5331: GenomeSpace: An environment for frictionless bioinformatics Cancer Research. 74: 5331-5331. DOI: 10.1158/1538-7445.Am2014-5331  0.43
2013 Campagne F, Dorff KC, Chambwe N, Robinson JT, Mesirov JP. Compression of structured high-throughput sequencing data. Plos One. 8: e79871. PMID 24260313 DOI: 10.1371/Journal.Pone.0079871  0.35
2013 Abazeed ME, Adams DJ, Hurov KE, Tamayo P, Creighton CJ, Sonkin D, Giacomelli AO, Du C, Fries DF, Wong KK, Mesirov JP, Loeffler JS, Schreiber SL, Hammerman PS, Meyerson M. Integrative radiogenomic profiling of squamous cell lung cancer. Cancer Research. 73: 6289-98. PMID 23980093 DOI: 10.1158/0008-5472.Can-13-1616  0.354
2013 Spidlen J, Barsky A, Breuer K, Carr P, Nazaire MD, Hill BA, Qian Y, Liefeld T, Reich M, Mesirov JP, Wilkinson P, Scheuermann RH, Sekaly RP, Brinkman RR. GenePattern flow cytometry suite. Source Code For Biology and Medicine. 8: 14. PMID 23822732 DOI: 10.1186/1751-0473-8-14  0.322
2013 Hagerstrand D, Tong A, Schumacher SE, Ilic N, Shen RR, Cheung HW, Vazquez F, Shrestha Y, Kim SY, Giacomelli AO, Rosenbluh J, Schinzel AC, Spardy NA, Barbie DA, Mermel CH, ... ... Mesirov JP, et al. Systematic interrogation of 3q26 identifies TLOC1 and SKIL as cancer drivers. Cancer Discovery. 3: 1044-57. PMID 23764425 DOI: 10.1158/2159-8290.Cd-12-0592  0.36
2013 Raeder MB, Birkeland E, Trovik J, Krakstad C, Shehata S, Schumacher S, Zack TI, Krohn A, Werner HM, Moody SE, Wik E, Stefansson IM, Holst F, Oyan AM, Tamayo P, ... Mesirov JP, et al. Integrated genomic analysis of the 8q24 amplification in endometrial cancers identifies ATAD2 as essential to MYC-dependent cancers. Plos One. 8: e54873. PMID 23393560 DOI: 10.1371/Journal.Pone.0054873  0.386
2013 Shao DD, Tsherniak A, Gopal S, Weir BA, Tamayo P, Stransky N, Schumacher SE, Zack TI, Beroukhim R, Garraway LA, Margolin AA, Root DE, Hahn WC, Mesirov JP. ATARiS: computational quantification of gene suppression phenotypes from multisample RNAi screens. Genome Research. 23: 665-78. PMID 23269662 DOI: 10.1101/Gr.143586.112  0.4
2013 Verhaak RG, Tamayo P, Yang JY, Hubbard D, Zhang H, Creighton CJ, Fereday S, Lawrence M, Carter SL, Mermel CH, Kostic AD, Etemadmoghadam D, Saksena G, Cibulskis K, Duraisamy S, ... ... Mesirov JP, et al. Prognostically relevant gene signatures of high-grade serous ovarian carcinoma. The Journal of Clinical Investigation. 123: 517-25. PMID 23257362 DOI: 10.1172/Jci65833  0.335
2013 Thorvaldsdóttir H, Robinson JT, Mesirov JP. Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration. Briefings in Bioinformatics. 14: 178-92. PMID 22517427 DOI: 10.1093/Bib/Bbs017  0.386
2013 Reich M, Liefeld J, Thorvaldsdottir H, Ocana M, Tabor T, Jang D, Mesirov JP. Abstract 5141: GenomeSpace: an environment for frictionless bioinformatics. Cancer Research. 73: 5141-5141. DOI: 10.1158/1538-7445.Am2013-5141  0.429
2012 Conley BA, Cavenagh MM, Lively TG, Eberhard DA, Williams PM, Bigbee WL, Mesirov JP, Polley MC, Kim KY, Tricoli JV. Criteria for use of omics-based predictors in NCI-sponsored clinical trials. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 58. PMID 28142454 DOI: 10.1200/Jco.2012.30.30_Suppl.58  0.339
2012 Rosenbluh J, Nijhawan D, Cox AG, Li X, Neal JT, Schafer EJ, Zack TI, Wang X, Tsherniak A, Schinzel AC, Shao DD, Schumacher SE, Weir BA, Vazquez F, Cowley GS, ... ... Mesirov JP, et al. β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis. Cell. 151: 1457-73. PMID 23245941 DOI: 10.1016/J.Cell.2012.11.026  0.334
2012 Nijhawan D, Zack TI, Ren Y, Strickland MR, Lamothe R, Schumacher SE, Tsherniak A, Besche HC, Rosenbluh J, Shehata S, Cowley GS, Weir BA, Goldberg AL, Mesirov JP, Root DE, et al. Cancer vulnerabilities unveiled by genomic loss. Cell. 150: 842-54. PMID 22901813 DOI: 10.1016/J.Cell.2012.07.023  0.42
2012 Ren Y, Cheung HW, von Maltzhan G, Agrawal A, Cowley GS, Weir BA, Boehm JS, Tamayo P, Karst AM, Liu JF, Hirsch MS, Mesirov JP, Drapkin R, Root DE, Lo J, et al. Targeted tumor-penetrating siRNA nanocomplexes for credentialing the ovarian cancer oncogene ID4. Science Translational Medicine. 4: 147ra112. PMID 22896676 DOI: 10.1126/Scitranslmed.3003778  0.365
2012 Pugh TJ, Weeraratne SD, Archer TC, Pomeranz Krummel DA, Auclair D, Bochicchio J, Carneiro MO, Carter SL, Cibulskis K, Erlich RL, Greulich H, Lawrence MS, Lennon NJ, McKenna A, Meldrim J, ... ... Mesirov JP, et al. Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations. Nature. 488: 106-10. PMID 22820256 DOI: 10.1038/Nature11329  0.319
2012 Lai L, Liberzon A, Hennessey J, Jiang G, Qi J, Mesirov JP, Ge SX. AraPath: a knowledgebase for pathway analysis in Arabidopsis. Bioinformatics (Oxford, England). 28: 2291-2. PMID 22760305 DOI: 10.1093/Bioinformatics/Bts421  0.4
2012 Wood KC, Konieczkowski DJ, Johannessen CM, Boehm JS, Tamayo P, Botvinnik OB, Mesirov JP, Hahn WC, Root DE, Garraway LA, Sabatini DM. MicroSCALE screening reveals genetic modifiers of therapeutic response in melanoma. Science Signaling. 5: rs4. PMID 22589389 DOI: 10.1126/Scisignal.2002612  0.325
2012 Barretina J, Caponigro G, Stransky N, Venkatesan K, Margolin AA, Kim S, Wilson CJ, Lehár J, Kryukov GV, Sonkin D, Reddy A, Liu M, Murray L, Berger MF, Monahan JE, ... ... Mesirov JP, et al. The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity. Nature. 483: 603-7. PMID 22460905 DOI: 10.1038/Nature11003  0.399
2012 Ren Y, Cheung HW, Drapkin R, Root D, Lo J, Fogal V, Ruoslahti E, Hahn W, Bhatia S, von Maltzahn G, Agrawal A, Cowley G, Weir B, Boehm J, Tamayo P, ... Mesirov J, et al. Abstract PR5: Treatment of ovarian cancer with targeted tumor-penetrating siRNA nanocomplexes Cancer Research. 72: PR5-PR5. DOI: 10.1158/1538-7445.Nonrna12-Pr5  0.368
2012 Pugh TJ, Cho Y, Archer T, Weeraratne D, Jones DTW, Jaeger N, Auclair D, Cibulskis K, Lawrence MS, Ramos AH, Shefler E, Sivachenko A, Tamayo P, Mesirov JP, Gabriel SB, et al. Abstract 4868: Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations within a wide spectrum of genetic heterogeneity Cancer Research. 72: 4868-4868. DOI: 10.1158/1538-7445.Am2012-4868  0.33
2012 Robinson JT, Thorvaldsdottir H, Mesirov J. Abstract 3968: Exploring cancer datasets in the integrative genomics viewer (IGV) Cancer Research. 72: 3968-3968. DOI: 10.1158/1538-7445.Am2012-3968  0.451
2012 Reich M, Liefeld J, Thorvaldsdottir H, Ocana M, Polk E, Jang D, Mesirov J. Abstract 3966: GenomeSpace: An environment for frictionless bioinformatics Cancer Research. 72: 3966-3966. DOI: 10.1158/1538-7445.Am2012-3966  0.433
2012 Weeraratne SD, Archer T, Pugh TJ, Hargreaves D, Yu F, Kautzman A, Jones DTW, Jaeger N, Tamayo P, Mesirov JP, Pfister SM, Lichter P, Crabtree G, Meyerson M, Pomeroy SL, et al. Abstract 1313: Mutually exclusive somatic mutations in WNT pathway medulloblastomas reveal a critical interaction between DDX3X and SMARCA4 Cancer Research. 72: 1313-1313. DOI: 10.1158/1538-7445.Am2012-1313  0.31
2011 Cheung HW, Cowley GS, Weir BA, Boehm JS, Rusin S, Scott JA, East A, Ali LD, Lizotte PH, Wong TC, Jiang G, Hsiao J, Mermel CH, Getz G, Barretina J, ... ... Mesirov JP, et al. Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer. Proceedings of the National Academy of Sciences of the United States of America. 108: 12372-7. PMID 21746896 DOI: 10.1073/Pnas.1109363108  0.399
2011 Liberzon A, Subramanian A, Pinchback R, Thorvaldsdóttir H, Tamayo P, Mesirov JP. Molecular signatures database (MSigDB) 3.0. Bioinformatics (Oxford, England). 27: 1739-40. PMID 21546393 DOI: 10.1093/Bioinformatics/Btr260  0.59
2011 Tamayo P, Cho YJ, Tsherniak A, Greulich H, Ambrogio L, Schouten-van Meeteren N, Zhou T, Buxton A, Kool M, Meyerson M, Pomeroy SL, Mesirov JP. Predicting relapse in patients with medulloblastoma by integrating evidence from clinical and genomic features. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 1415-23. PMID 21357789 DOI: 10.1200/Jco.2010.28.1675  0.345
2011 Robinson JT, Thorvaldsdóttir H, Winckler W, Guttman M, Lander ES, Getz G, Mesirov JP. Integrative genomics viewer. Nature Biotechnology. 29: 24-6. PMID 21221095 DOI: 10.1038/Nbt.1754  0.417
2011 Cho YJ, Tsherniak A, Tamayo P, Santagata S, Ligon A, Greulich H, Berhoukim R, Amani V, Goumnerova L, Eberhart CG, Lau CC, Olson JM, Gilbertson RJ, Gajjar A, Delattre O, ... ... Mesirov JP, et al. Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 1424-30. PMID 21098324 DOI: 10.1200/Jco.2010.28.5148  0.365
2011 Galili N, Tamayo P, Botvinnik OB, Mesirov JP, Zikria J, Brown G, Raza A. Gene Expression Studies May Identify Lower Risk Myelodysplastic Syndrome Patients Likely to Respond to Therapy with Ezatiostat Hydrochloride (TLK199) Blood. 118: 2779-2779. DOI: 10.1182/Blood.V118.21.2779.2779  0.335
2011 Barretina J, Stransky N, Caponigro G, Kim S, Margolin A, Venkhatesan K, Kryukov G, Berger M, Monahan J, Morais P, Meltzer J, Mahan S, Sonkin D, Raman P, Jones M, ... ... Mesirov J, et al. Abstract 5455: Integrative analysis of the Cancer Cell Line Encyclopedia reveals genetic and transcriptional predictors of compound sensitivity Cancer Research. 71: 5455-5455. DOI: 10.1158/1538-7445.Am2011-5455  0.4
2011 Cho Y, Tamayo P, Tsherniak A, Meyerson M, Mesirov JP, Pomeroy SL. Abstract 4760: Molecular classification and risk-stratification in medulloblastoma using an integrative genomic approach Cancer Research. 71: 4760-4760. DOI: 10.1158/1538-7445.Am2011-4760  0.381
2010 Jagani Z, Mora-Blanco EL, Sansam CG, McKenna ES, Wilson B, Chen D, Klekota J, Tamayo P, Nguyen PT, Tolstorukov M, Park PJ, Cho YJ, Hsiao K, Buonamici S, Pomeroy SL, ... Mesirov JP, et al. Loss of the tumor suppressor Snf5 leads to aberrant activation of the Hedgehog-Gli pathway. Nature Medicine. 16: 1429-33. PMID 21076395 DOI: 10.1038/Nm.2251  0.31
2010 Wolfer A, Wittner BS, Irimia D, Flavin RJ, Lupien M, Gunawardane RN, Meyer CA, Lightcap ES, Tamayo P, Mesirov JP, Liu XS, Shioda T, Toner M, Loda M, Brown M, et al. MYC regulation of a "poor-prognosis" metastatic cancer cell state. Proceedings of the National Academy of Sciences of the United States of America. 107: 3698-703. PMID 20133671 DOI: 10.1073/Pnas.0914203107  0.344
2010 Verhaak RG, Hoadley KA, Purdom E, Wang V, Qi Y, Wilkerson MD, Miller CR, Ding L, Golub T, Mesirov JP, Alexe G, Lawrence M, O'Kelly M, Tamayo P, Weir BA, et al. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell. 17: 98-110. PMID 20129251 DOI: 10.1016/J.Ccr.2009.12.020  0.43
2010 Wolfer A, Wittner BS, Irimia D, Flavin RJ, Lupien M, Gunawardane RN, Meyer CA, Lightcap ES, Tamayo P, Mesirov JP, Liu XS, Shioda T, Toner M, Loda M, Brown M, et al. Abstract 3300: MYC regulation of a “poor prognosis” metastatic cancer cell state Cancer Research. 70: 3300-3300. DOI: 10.1158/1538-7445.Am10-3300  0.347
2010 Stransky N, Venkatesan K, Barretina J, Caponigro G, Margolin A, Morrissey M, Raman P, Getz G, Berger M, Johannessen C, Callahan A, Morais P, Mahan S, Gupta S, Onofrio R, ... ... Mesirov J, et al. Abstract PR4: Integrative analysis of genomic and pharmacologic data from the Cancer Cell Line Encyclopedia Clinical Cancer Research. 16. DOI: 10.1158/1078-0432.Tcmusa10-Pr4  0.4
2009 Barbie DA, Tamayo P, Boehm JS, Kim SY, Moody SE, Dunn IF, Schinzel AC, Sandy P, Meylan E, Scholl C, Fröhling S, Chan EM, Sos ML, Michel K, Mermel C, ... ... Mesirov JP, et al. Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1. Nature. 462: 108-12. PMID 19847166 DOI: 10.1038/Nature08460  0.351
2009 Robinson J, Thorvaldsdottir H, Nazaire M, Winckler W, Reich M, Getz G, Mesirov J. Abstract C60: The integrative genomics viewer Cancer Research. 69. DOI: 10.1158/0008-5472.Fbcr09-C60  0.432
2008 Kuehn H, Liberzon A, Reich M, Mesirov JP. Using GenePattern for gene expression analysis. Current Protocols in Bioinformatics / Editoral Board, Andreas D. Baxevanis ... [Et Al.]. Unit 7.12. PMID 18551415 DOI: 10.1002/0471250953.Bi0712S22  0.377
2008 Mishra PJ, Mishra PJ, Humeniuk R, Medina DJ, Alexe G, Mesirov JP, Ganesan S, Glod JW, Banerjee D. Carcinoma-associated fibroblast-like differentiation of human mesenchymal stem cells. Cancer Research. 68: 4331-9. PMID 18519693 DOI: 10.1158/0008-5472.Can-08-0943  0.319
2008 Xu L, Shen SS, Hoshida Y, Subramanian A, Ross K, Brunet JP, Wagner SN, Ramaswamy S, Mesirov JP, Hynes RO. Gene expression changes in an animal melanoma model correlate with aggressiveness of human melanoma metastases. Molecular Cancer Research : McR. 6: 760-9. PMID 18505921 DOI: 10.1158/1541-7786.Mcr-07-0344  0.561
2007 Alexe G, Dalgin GS, Scanfeld D, Tamayo P, Mesirov JP, Ganesan S, Delisi C, Bhanot G. Breast cancer stratification from analysis of micro-array data of micro-dissected specimens. Genome Informatics. International Conference On Genome Informatics. 18: 130-40. PMID 18546481 DOI: 10.11234/Gi1990.18.130  0.343
2007 Hoshida Y, Brunet JP, Tamayo P, Golub TR, Mesirov JP. Subclass mapping: identifying common subtypes in independent disease data sets. Plos One. 2: e1195. PMID 18030330 DOI: 10.1371/Journal.Pone.0001195  0.38
2007 Alexe G, Dalgin GS, Scanfeld D, Tamayo P, Mesirov JP, DeLisi C, Harris L, Barnard N, Martel M, Levine AJ, Ganesan S, Bhanot G. High expression of lymphocyte-associated genes in node-negative HER2+ breast cancers correlates with lower recurrence rates. Cancer Research. 67: 10669-76. PMID 18006808 DOI: 10.1158/0008-5472.Can-07-0539  0.335
2007 Karlsson EK, Baranowska I, Wade CM, Salmon Hillbertz NH, Zody MC, Anderson N, Biagi TM, Patterson N, Pielberg GR, Kulbokas EJ, Comstock KE, Keller ET, Mesirov JP, von Euler H, Kämpe O, et al. Efficient mapping of mendelian traits in dogs through genome-wide association. Nature Genetics. 39: 1321-8. PMID 17906626 DOI: 10.1038/Ng.2007.10  0.62
2007 Getz G, Höfling H, Mesirov JP, Golub TR, Meyerson M, Tibshirani R, Lander ES. Comment on "The consensus coding sequences of human breast and colorectal cancers". Science (New York, N.Y.). 317: 1500. PMID 17872428 DOI: 10.1126/Science.1138764  0.314
2007 Subramanian A, Kuehn H, Gould J, Tamayo P, Mesirov JP. GSEA-P: a desktop application for Gene Set Enrichment Analysis. Bioinformatics (Oxford, England). 23: 3251-3. PMID 17644558 DOI: 10.1093/Bioinformatics/Btm369  0.561
2007 Tamayo P, Scanfeld D, Ebert BL, Gillette MA, Roberts CW, Mesirov JP. Metagene projection for cross-platform, cross-species characterization of global transcriptional states. Proceedings of the National Academy of Sciences of the United States of America. 104: 5959-64. PMID 17389406 DOI: 10.1073/Pnas.0701068104  0.358
2006 Engels R, Yu T, Burge C, Mesirov JP, DeCaprio D, Galagan JE. Combo: A whole genome comparative browser Bioinformatics. 22: 1782-1783. PMID 16709588 DOI: 10.1093/Bioinformatics/Btl193  0.372
2006 Gould J, Getz G, Monti S, Reich M, Mesirov JP. Comparative gene marker selection suite. Bioinformatics (Oxford, England). 22: 1924-5. PMID 16709585 DOI: 10.1093/Bioinformatics/Btl196  0.361
2005 Isakoff MS, Sansam CG, Tamayo P, Subramanian A, Evans JA, Fillmore CM, Wang X, Biegel JA, Pomeroy SL, Mesirov JP, Roberts CW. Inactivation of the Snf5 tumor suppressor stimulates cell cycle progression and cooperates with p53 loss in oncogenic transformation. Proceedings of the National Academy of Sciences of the United States of America. 102: 17745-50. PMID 16301525 DOI: 10.1073/Pnas.0509014102  0.557
2005 Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA, Paulovich A, Pomeroy SL, Golub TR, Lander ES, Mesirov JP. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proceedings of the National Academy of Sciences of the United States of America. 102: 15545-50. PMID 16199517 DOI: 10.1073/Pnas.0506580102  0.607
2005 Vinson JP, Jaffe DB, O'Neill K, Karlsson EK, Stange-Thomann N, Anderson S, Mesirov JP, Satoh N, Satou Y, Nusbaum C, Birren B, Galagan JE, Lander ES. Assembly of polymorphic genomes: algorithms and application to Ciona savignyi. Genome Research. 15: 1127-35. PMID 16077012 DOI: 10.1101/Gr.3722605  0.63
2005 Liefeld T, Reich M, Gould J, Zhang P, Tamayo P, Mesirov JP. GeneCruiser: a web service for the annotation of microarray data. Bioinformatics (Oxford, England). 21: 3681-2. PMID 16030072 DOI: 10.1093/Bioinformatics/Bti587  0.384
2005 Sweet-Cordero A, Mukherjee S, Subramanian A, You H, Roix JJ, Ladd-Acosta C, Mesirov J, Golub TR, Jacks T. An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis. Nature Genetics. 37: 48-55. PMID 15608639 DOI: 10.1038/Ng1490  0.599
2005 Mikkelsen TS, Galagan JE, Mesirov JP. Improving genome annotations using phylogenetic profile anomaly detection. Bioinformatics (Oxford, England). 21: 464-70. PMID 15374867 DOI: 10.1093/Bioinformatics/Bti027  0.4
2004 Jaillon O, Aury JM, Brunet F, Petit JL, Stange-Thomann N, Mauceli E, Bouneau L, Fischer C, Ozouf-Costaz C, Bernot A, Nicaud S, Jaffe D, Fisher S, Lutfalla G, Dossat C, ... ... Mesirov J, et al. Genome duplication in the teleost fish Tetraodon nigroviridis reveals the early vertebrate proto-karyotype. Nature. 431: 946-57. PMID 15496914 DOI: 10.1038/Nature03025  0.374
2004 Brunet JP, Tamayo P, Golub TR, Mesirov JP. Metagenes and molecular pattern discovery using matrix factorization. Proceedings of the National Academy of Sciences of the United States of America. 101: 4164-9. PMID 15016911 DOI: 10.1073/Pnas.0308531101  0.342
2004 Reich M, Ohm K, Angelo M, Tamayo P, Mesirov JP. GeneCluster 2.0: An advanced toolset for bioarray analysis Bioinformatics. 20: 1797-1798. PMID 14988123 DOI: 10.1093/Bioinformatics/Bth138  0.328
2003 Mootha VK, Lindgren CM, Eriksson KF, Subramanian A, Sihag S, Lehar J, Puigserver P, Carlsson E, RidderstrÃ¥le M, Laurila E, Houstis N, Daly MJ, Patterson N, Mesirov JP, Golub TR, et al. PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nature Genetics. 34: 267-73. PMID 12808457 DOI: 10.1038/Ng1180  0.564
2003 Jaffe DB, Butler J, Gnerre S, Mauceli E, Lindblad-Toh K, Mesirov JP, Zody MC, Lander ES. Whole-genome sequence assembly for mammalian genomes: Arachne 2. Genome Research. 13: 91-6. PMID 12529310 DOI: 10.1101/Gr.828403  0.347
2003 Rifkin R, Mukherjee S, Tamayo P, Ramaswamy S, Yeang CH, Angelo M, Reich M, Poggio T, Lander ES, Golub TR, Mesirov JP. An analytical method for multiclass molecular cancer classification Siam Review. 45: 706-723. DOI: 10.1137/S0036144502411986  0.367
2002 Waterston RH, Lindblad-Toh K, Birney E, Rogers J, Abril JF, Agarwal P, Agarwala R, Ainscough R, Alexandersson M, An P, Antonarakis SE, Attwood J, Baertsch R, Bailey J, ... ... Mesirov JP, et al. Initial sequencing and comparative analysis of the mouse genome. Nature. 420: 520-62. PMID 12466850 DOI: 10.1038/Nature01262  0.654
2002 Pomeroy SL, Tamayo P, Gaasenbeek M, Sturla LM, Angelo M, McLaughlin ME, Kim JY, Goumnerova LC, Black PM, Lau C, Allen JC, Zagzag D, Olson JM, Curran T, Wetmore C, ... ... Mesirov JP, et al. Prediction of central nervous system embryonal tumour outcome based on gene expression. Nature. 415: 436-42. PMID 11807556 DOI: 10.1038/415436A  0.309
2002 Shipp MA, Ross KN, Tamayo P, Weng AP, Kutok JL, Aguiar RC, Gaasenbeek M, Angelo M, Reich M, Pinkus GS, Ray TS, Koval MA, Last KW, Norton A, Lister TA, ... Mesirov J, et al. Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning. Nature Medicine. 8: 68-74. PMID 11786909 DOI: 10.1038/Nm0102-68  0.312
2001 Ramaswamy S, Tamayo P, Rifkin R, Mukherjee S, Yeang CH, Angelo M, Ladd C, Reich M, Latulippe E, Mesirov JP, Poggio T, Gerald W, Loda M, Lander ES, Golub TR. Multiclass cancer diagnosis using tumor gene expression signatures. Proceedings of the National Academy of Sciences of the United States of America. 98: 15149-54. PMID 11742071 DOI: 10.1073/Pnas.211566398  0.383
2001 Staunton JE, Slonim DK, Coller HA, Tamayo P, Angelo MJ, Park J, Scherf U, Lee JK, Reinhold WO, Weinstein JN, Mesirov JP, Lander ES, Golub TR. Chemosensitivity prediction by transcriptional profiling. Proceedings of the National Academy of Sciences of the United States of America. 98: 10787-92. PMID 11553813 DOI: 10.1073/Pnas.191368598  0.378
2001 Yeang CH, Ramaswamy S, Tamayo P, Mukherjee S, Rifkin RM, Angelo M, Reich M, Lander E, Mesirov J, Golub T. Molecular classification of multiple tumor types. Bioinformatics (Oxford, England). 17: S316-22. PMID 11473023 DOI: 10.1093/Bioinformatics/17.Suppl_1.S316  0.316
2001 Lander ES, Linton LM, Birren B, Nusbaum C, Zody MC, Baldwin J, Devon K, Dewar K, Doyle M, FitzHugh W, Funke R, Gage D, Harris K, Heaford A, Howland J, ... ... Mesirov JP, et al. Initial sequencing and analysis of the human genome. Nature. 409: 860-921. PMID 11237011 DOI: 10.1038/35057062  0.57
2001 Lander ES, Linton LM, Birren B, Nusbaum C, Zody MC, Baldwin J, Devon K, Dewar K, Doyle M, Fitzhugh W, Funke R, Gage D, Harris K, Heaford A, Howland J, ... ... Mesirov JP, et al. Erratum: Initial sequencing and analysis of the human genome: International Human Genome Sequencing Consortium (Nature (2001) 409 (860-921)) Nature. 412: 565-566. DOI: 10.1038/35087627  0.559
2000 Batzoglou S, Pachter L, Mesirov JP, Berger B, Lander ES. Human and mouse gene structure: comparative analysis and application to exon prediction. Genome Research. 10: 950-8. PMID 10899144 DOI: 10.1101/Gr.10.7.950  0.373
1999 Batzoglou S, Berger B, Mesirov J, Lander ES. Sequencing a genome by walking with clone-end sequences: a mathematical analysis. Genome Research. 9: 1163-74. PMID 10613838 DOI: 10.1101/Gr.9.12.1163  0.343
1999 Golub TR, Slonim DK, Tamayo P, Huard C, Gaasenbeek M, Mesirov JP, Coller H, Loh ML, Downing JR, Caligiuri MA, Bloomfield CD, Lander ES. Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science (New York, N.Y.). 286: 531-7. PMID 10521349 DOI: 10.1126/Science.286.5439.531  0.326
1999 Tamayo P, Slonim D, Mesirov J, Zhu Q, Kitareewan S, Dmitrovsky E, Lander ES, Golub TR. Interpreting patterns of gene expression with self-organizing maps: methods and application to hematopoietic differentiation. Proceedings of the National Academy of Sciences of the United States of America. 96: 2907-12. PMID 10077610 DOI: 10.1073/Pnas.96.6.2907  0.375
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