| Year |
Citation |
Score |
| 2022 |
Anderson CL, Munawar S, Reilly L, Kamp TJ, January CT, Delisle BP, Eckhardt LL. How Functional Genomics Can Keep Pace With VUS Identification. Frontiers in Cardiovascular Medicine. 9: 900431. PMID 35859585 DOI: 10.3389/fcvm.2022.900431 |
0.561 |
|
| 2022 |
Kekenes-Huskey PM, Burgess DE, Sun B, Bartos DC, Rozmus ER, Anderson CL, January CT, Eckhardt LL, Delisle BP. Mutation-Specific Differences in Kv7.1 () and Kv11.1 () Channel Dysfunction and Long QT Syndrome Phenotypes. International Journal of Molecular Sciences. 23. PMID 35806392 DOI: 10.3390/ijms23137389 |
0.806 |
|
| 2020 |
Ono M, Burgess DE, Schroder EA, Elayi CS, Anderson CL, January CT, Sun B, Immadisetty K, Kekenes-Huskey PM, Delisle BP. Long QT Syndrome Type 2: Emerging Strategies for Correcting Class 2 () Mutations and Identifying New Patients. Biomolecules. 10. PMID 32759882 DOI: 10.3390/biom10081144 |
0.715 |
|
| 2020 |
Ng K, Titus EW, Lieve KV, Roston TM, Mazzanti A, Deiter FH, Denjoy I, Ingles J, Till J, Robyns T, Connors SP, Steinberg C, Abrams DJ, Pang B, Scheinman MM, ... ... January CT, et al. An International Multi-Center Evaluation of Inheritance Patterns, Arrhythmic Risks, and Underlying Mechanisms of - Catecholaminergic Polymorphic Ventricular Tachycardia. Circulation. PMID 32693635 DOI: 10.1161/Circulationaha.120.045723 |
0.322 |
|
| 2020 |
Anderson CL, Routes TC, Eckhardt LL, Delisle BP, January CT, Kamp TJ. A rapid solubility assay of protein domain misfolding for pathogenicity assessment of rare DNA sequence variants. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 32475984 DOI: 10.1038/S41436-020-0842-1 |
0.568 |
|
| 2020 |
Qile M, Ji Y, Golden TD, Houtman MJC, Romunde F, Fransen D, van Ham WB, IJzerman AP, January CT, Heitman LH, Stary-Weinzinger A, Delisle BP, van der Heyden MAG. LUF7244 plus dofetilide rescues aberrant Kv11.1 trafficking and produces functional IKv11.1. Molecular Pharmacology. PMID 32241959 DOI: 10.1124/mol.119.118190 |
0.677 |
|
| 2019 |
Mellor GJ, Panwar P, Lee AK, Steinberg C, Hathaway JA, Bartels K, Christian S, Balaji S, Roberts JD, Simpson CS, Boczek NJ, Tester DJ, Radbill AE, Mok NS, Hamilton RM, ... ... January C, et al. Type 8 long QT syndrome: pathogenic variants in CACNA1C-encoded Cav1.2 cluster in STAC protein binding site. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups On Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. PMID 31408100 DOI: 10.1093/Europace/Euz215 |
0.346 |
|
| 2018 |
Hall AR, Anderson CL, Smith JL, Mirshahi T, Elayi CS, January CT, Delisle BP. Visualizing Mutation-Specific Differences in the Trafficking-Deficient Phenotype of Kv11.1 Proteins Linked to Long QT Syndrome Type 2. Frontiers in Physiology. 9: 584. PMID 29875689 DOI: 10.3389/Fphys.2018.00584 |
0.715 |
|
| 2018 |
Smith JL, Tester DJ, Hall AR, Burgess DE, Hsu CC, Claude Elayi S, Anderson CL, January CT, Luo JZ, Hartzel DN, Mirshahi UL, Murray MF, Mirshahi T, Ackerman MJ, Delisle BP. Functional Invalidation of Putative Sudden Infant Death Syndrome-Associated Variants in the -Encoded Kv11.1 Channel. Circulation. Arrhythmia and Electrophysiology. 11: e005859. PMID 29752375 DOI: 10.1161/Circep.117.005859 |
0.64 |
|
| 2018 |
Delisle BP, January CT. Advancing precision medicine for the treatment of long-QT syndrome type 2: shedding light on lumacaftor. European Heart Journal. 39: 1456-1458. PMID 29040441 DOI: 10.1093/Eurheartj/Ehx561 |
0.594 |
|
| 2018 |
Burgess DE, Smith JL, Amin AS, Anderson CL, January CT, Delisle BP. Changes in IKR Amplitude (NOT Gating) is the Key Determinant for Ventricular Action Potential Prolongation Biophysical Journal. 114: 311a-312a. DOI: 10.1016/J.Bpj.2017.11.1760 |
0.601 |
|
| 2017 |
Van Ert HA, McCune EC, Orland KM, Maginot KR, Von Bergen NH, January CT, Eckhardt LL. Flecainide treats a novel mutation associated with Andersen-Tawil syndrome. Heartrhythm Case Reports. 3: 151-154. PMID 28491792 DOI: 10.1016/J.Hrcr.2016.11.009 |
0.415 |
|
| 2016 |
Smith JL, Anderson CL, Burgess DE, Elayi CS, January CT, Delisle BP. Molecular pathogenesis of long QT syndrome type 2. Journal of Arrhythmia. 32: 373-380. PMID 27761161 DOI: 10.1016/J.Joa.2015.11.009 |
0.702 |
|
| 2015 |
Yue Y, Castrichini M, Srivastava U, Fabris F, Shah K, Li Z, Qu Y, El-Sherif N, Zhou Z, January C, Hussain MM, Jiang XC, Sobie EA, Wahren-Herlenius M, Chahine M, et al. Pathogenesis of the Novel Autoimmune-Associated Long QT Syndrome. Circulation. PMID 25995318 DOI: 10.1161/Circulationaha.115.009800 |
0.385 |
|
| 2015 |
Smith JL, Anderson CL, Burgess DE, Elayi CS, January CT, Delisle BP. Molecular pathogenesis of long QT syndrome type 2 Journal of Arrhythmia. DOI: 10.1016/j.joa.2015.11.009 |
0.578 |
|
| 2014 |
Lin EC, Moungey BM, Lim E, Concannon SP, Anderson CL, Kyle JW, Makielski JC, Balijepalli SY, January CT. Mouse ERG K(+) channel clones reveal differences in protein trafficking and function. Journal of the American Heart Association. 3: e001491. PMID 25497881 DOI: 10.1161/Jaha.114.001491 |
0.504 |
|
| 2014 |
Anderson CL, Kuzmicki CE, Childs RR, Hintz CJ, Delisle BP, January CT. Large-scale mutational analysis of Kv11.1 reveals molecular insights into type 2 long QT syndrome. Nature Communications. 5: 5535. PMID 25417810 DOI: 10.1038/Ncomms6535 |
0.724 |
|
| 2014 |
Spencer CI, Baba S, Nakamura K, Hua EA, Sears MA, Fu CC, Zhang J, Balijepalli S, Tomoda K, Hayashi Y, Lizarraga P, Wojciak J, Scheinman MM, Aalto-Setälä K, Makielski JC, ... January CT, et al. Calcium transients closely reflect prolonged action potentials in iPSC models of inherited cardiac arrhythmia. Stem Cell Reports. 3: 269-81. PMID 25254341 DOI: 10.1016/J.Stemcr.2014.06.003 |
0.46 |
|
| 2014 |
Kalscheur MM, Vaidyanathan R, Orland KM, Abozeid S, Fabry N, Maginot KR, January CT, Makielski JC, Eckhardt LL. KCNJ2 mutation causes an adrenergic-dependent rectification abnormality with calcium sensitivity and ventricular arrhythmia. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 11: 885-94. PMID 24561538 DOI: 10.1016/J.Hrthm.2014.02.015 |
0.436 |
|
| 2014 |
Vaidyanathan R, Kyle J, Capes DL, Kamp TJ, January CT, Eckhardt LL, Makielski JC. Human Induced Pluripotent Stem Cell Derived Cardiomyocytes (HIPS-CM's): An Expression Model System for Investigating Cardiac Channelopathies Biophysical Journal. 106: 553a. DOI: 10.1016/J.Bpj.2013.11.3078 |
0.387 |
|
| 2013 |
Smith JL, Reloj AR, Nataraj PS, Bartos DC, Schroder EA, Moss AJ, Ohno S, Horie M, Anderson CL, January CT, Delisle BP. Pharmacological correction of long QT-linked mutations in KCNH2 (hERG) increases the trafficking of Kv11.1 channels stored in the transitional endoplasmic reticulum. American Journal of Physiology. Cell Physiology. 305: C919-30. PMID 23864605 DOI: 10.1152/Ajpcell.00406.2012 |
0.831 |
|
| 2013 |
Su X, Theberge AB, January CT, Beebe DJ. Effect of microculture on cell metabolism and biochemistry: do cells get stressed in microchannels? Analytical Chemistry. 85: 1562-70. PMID 23327437 DOI: 10.1021/Ac3027228 |
0.337 |
|
| 2013 |
Behr ER, January C, Schulze-Bahr E, Grace AA, Kääb S, Fiszman M, Gathers S, Buckman S, Youssef A, Pirmohamed M, Roden D. The International Serious Adverse Events Consortium (iSAEC) phenotype standardization project for drug-induced torsades de pointes. European Heart Journal. 34: 1958-63. PMID 22752616 DOI: 10.1093/Eurheartj/Ehs172 |
0.321 |
|
| 2013 |
Smith JL, Reloj AR, Nataraj PS, Bartos DC, January CT, Delisle BP. Cellular Mechanism for the Pharmacological Correction of hERG Mutations Linked to the Long QT Syndrome Biophysical Journal. 104: 266a. DOI: 10.1016/J.Bpj.2012.11.1496 |
0.832 |
|
| 2012 |
Knoche JW, Orland KM, January CT, Maginot KR. Atrial Fibrillation and Long QT Syndrome Presenting in a 12-Year-Old Girl. Case Reports in Pediatrics. 2012: 124838. PMID 23193492 DOI: 10.1155/2012/124838 |
0.434 |
|
| 2012 |
Balijepalli SY, Lim E, Concannon SP, Chew CL, Holzem KE, Tester DJ, Ackerman MJ, Delisle BP, Balijepalli RC, January CT. Mechanism of loss of Kv11.1 K+ current in mutant T421M-Kv11.1-expressing rat ventricular myocytes: Interaction of trafficking and gating Circulation. 126: 2809-2818. PMID 23136156 DOI: 10.1161/Circulationaha.112.118018 |
0.727 |
|
| 2011 |
Ma J, Guo L, Fiene SJ, Anson BD, Thomson JA, Kamp TJ, Kolaja KL, Swanson BJ, January CT. High purity human-induced pluripotent stem cell-derived cardiomyocytes: electrophysiological properties of action potentials and ionic currents. American Journal of Physiology. Heart and Circulatory Physiology. 301: H2006-17. PMID 21890694 DOI: 10.1152/Ajpheart.00694.2011 |
0.404 |
|
| 2011 |
Smith JL, McBride CM, Nataraj PS, Bartos DC, January CT, Delisle BP. Trafficking-deficient hERG K⺠channels linked to long QT syndrome are regulated by a microtubule-dependent quality control compartment in the ER. American Journal of Physiology. Cell Physiology. 301: C75-85. PMID 21490315 DOI: 10.1152/Ajpcell.00494.2010 |
0.828 |
|
| 2011 |
Cheng J, Tester DJ, Tan BH, Valdivia CR, Kroboth S, Ye B, January CT, Ackerman MJ, Makielski JC. The common African American polymorphism SCN5A-S1103Y interacts with mutation SCN5A-R680H to increase late Na current. Physiological Genomics. 43: 461-6. PMID 21385947 DOI: 10.1152/Physiolgenomics.00198.2010 |
0.402 |
|
| 2011 |
Best JM, Foell JD, Buss CR, Delisle BP, Balijepalli RC, January CT, Kamp TJ. Small GTPase Rab11b regulates degradation of surface membrane L-type Cav1.2 channels. American Journal of Physiology. Cell Physiology. 300: C1023-33. PMID 21248079 DOI: 10.1152/Ajpcell.00288.2010 |
0.655 |
|
| 2011 |
Su X, Young EW, Underkofler HA, Kamp TJ, January CT, Beebe DJ. Microfluidic cell culture and its application in high-throughput drug screening: cardiotoxicity assay for hERG channels. Journal of Biomolecular Screening. 16: 101-11. PMID 21131594 DOI: 10.1177/1087057110386218 |
0.417 |
|
| 2011 |
Peal DS, Mills RW, Lynch SN, Mosley JM, Lim E, Ellinor PT, January CT, Peterson RT, Milan DJ. Novel chemical suppressors of long QT syndrome identified by an in vivo functional screen. Circulation. 123: 23-30. PMID 21098441 DOI: 10.1161/Circulationaha.110.003731 |
0.334 |
|
| 2011 |
Bartos DC, Duchatelet S, Burgess DE, Klug D, Denjoy I, Peat R, Lupoglazoff JM, Fressart V, Berthet M, Ackerman MJ, January CT, Guicheney P, Delisle BP. R231C mutation in KCNQ1 causes long QT syndrome type 1 and familial atrial fibrillation. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 8: 48-55. PMID 20850564 DOI: 10.1016/J.Hrthm.2010.09.010 |
0.809 |
|
| 2011 |
Lin EC, Moungey BM, Balijepalli SY, January CT. Different Molecular Phenotypes of LQT2-Linked hERG1a Mutations in the Same Amino Acid Biophysical Journal. 100: 30a. DOI: 10.1016/J.Bpj.2010.12.366 |
0.534 |
|
| 2011 |
Smith JL, Nataraj P, January CT, Delisle BP. The Trafficking of Mutant HERG K+ Channels Linked to Long QT Syndrome are Regulated by a Subdomain in the Endoplasmic Reticulum Biophysical Journal. 100: 427a. DOI: 10.1016/J.Bpj.2010.12.2526 |
0.697 |
|
| 2010 |
Amin AS, Klemens CA, Verkerk AO, Meregalli PG, Asghari-Roodsari A, de Bakker JM, January CT, Wilde AA, Tan HL. Fever-triggered ventricular arrhythmias in Brugada syndrome and type 2 long-QT syndrome. Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation. 18: 165-9. PMID 20390067 DOI: 10.1007/Bf03091755 |
0.504 |
|
| 2010 |
Lin EC, Holzem KM, Anson BD, Moungey BM, Balijepalli SY, Tester DJ, Ackerman MJ, Delisle BP, Balijepalli RC, January CT. Properties of WT and mutant hERG K(+) channels expressed in neonatal mouse cardiomyocytes. American Journal of Physiology. Heart and Circulatory Physiology. 298: H1842-9. PMID 20363883 DOI: 10.1152/Ajpheart.01236.2009 |
0.753 |
|
| 2010 |
Balijepalli SY, Anderson CL, Lin EC, January CT. Rescue of mutated cardiac ion channels in inherited arrhythmia syndromes. Journal of Cardiovascular Pharmacology. 56: 113-22. PMID 20224422 DOI: 10.1097/Fjc.0B013E3181Dab014 |
0.532 |
|
| 2010 |
Smith JL, McBride CM, Bartos DC, January CT, Delisle B. Microtubule Dependent Mechanisms Regulate the Trafficking Deficient Phenotype of hERG Mutations Linked to Long QT Syndrome Biophysical Journal. 98: 118a-119a. DOI: 10.1016/J.Bpj.2009.12.647 |
0.826 |
|
| 2009 |
Cheng J, Van Norstrand DW, Medeiros-Domingo A, Valdivia C, Tan BH, Ye B, Kroboth S, Vatta M, Tester DJ, January CT, Makielski JC, Ackerman MJ. Alpha1-syntrophin mutations identified in sudden infant death syndrome cause an increase in late cardiac sodium current. Circulation. Arrhythmia and Electrophysiology. 2: 667-76. PMID 20009079 DOI: 10.1161/Circep.109.891440 |
0.46 |
|
| 2009 |
Shimizu W, Moss AJ, Wilde AA, Towbin JA, Ackerman MJ, January CT, Tester DJ, Zareba W, Robinson JL, Qi M, Vincent GM, Kaufman ES, Hofman N, Noda T, Kamakura S, et al. Genotype-phenotype aspects of type 2 long QT syndrome. Journal of the American College of Cardiology. 54: 2052-62. PMID 19926013 DOI: 10.1016/J.Jacc.2009.08.028 |
0.406 |
|
| 2009 |
Wu L, Rajamani S, Li H, January CT, Shryock JC, Belardinelli L. Reduction of repolarization reserve unmasks the proarrhythmic role of endogenous late Na(+) current in the heart. American Journal of Physiology. Heart and Circulatory Physiology. 297: H1048-57. PMID 19592609 DOI: 10.1152/Ajpheart.00467.2009 |
0.33 |
|
| 2009 |
Delisle BP, Underkofler HA, Moungey BM, Slind JK, Kilby JA, Best JM, Foell JD, Balijepalli RC, Kamp TJ, January CT. Small GTPase determinants for the Golgi processing and plasmalemmal expression of human ether-a-go-go related (hERG) K+ channels. The Journal of Biological Chemistry. 284: 2844-53. PMID 19029296 DOI: 10.1074/Jbc.M807289200 |
0.729 |
|
| 2009 |
Smith JL, Bartos DC, January CT, Delisle BP. Trafficking-deficient LQT2 Mutations Disrupt Different Steps of hERG Channel Transport Biophysical Journal. 96: 190a. DOI: 10.1016/J.Bpj.2008.12.894 |
0.826 |
|
| 2009 |
Balijepalli SY, Tester DJ, Wang J, Holzem KE, Chew CL, Anson BD, Kamp TJ, Ackerman MJ, January CT. Mechanism Of IKr Loss In Mutant T421M-hERG Expressing Rat Ventricular Myocytes Biophysical Journal. 96: 190a. DOI: 10.1016/J.Bpj.2008.12.893 |
0.468 |
|
| 2009 |
Lin E, Moungey B, Delisle BP, January CT. LQT2 Linked Mutations E444d And P451l In The S1-S2 Linker Lead To Biophysical Abnormalities Of Herg Channels Biophysical Journal. 96: 189a. DOI: 10.1016/J.Bpj.2008.12.887 |
0.687 |
|
| 2009 |
Bartos DC, Smith JL, Kilby JA, January CT, Delisle BP. Wild-Type KCNQ1 Modulates the Gating of the LQT1 Mutation R231C Biophysical Journal. 96: 380a. DOI: 10.1016/J.Bpj.2008.12.2847 |
0.814 |
|
| 2008 |
Amin AS, Herfst LJ, Delisle BP, Klemens CA, Rook MB, Bezzina CR, Underkofler HAS, Holzem KM, Ruijter JM, Tan HL, January CT, Wilde AAM. Fever-induced QTc prolongation and ventricular arrhythmias in individuals with type 2 congenital long QT syndrome Journal of Clinical Investigation. 118: 2552-2561. PMID 18551196 DOI: 10.1172/Jci35337 |
0.71 |
|
| 2008 |
Takemasa H, Nagatomo T, Abe H, Kawakami K, Igarashi T, Tsurugi T, Kabashima N, Tamura M, Okazaki M, Delisle BP, January CT, Otsuji Y. Coexistence of hERG current block and disruption of protein trafficking in ketoconazole-induced long QT syndrome British Journal of Pharmacology. 153: 439-447. PMID 17965736 DOI: 10.1038/Sj.Bjp.0707537 |
0.729 |
|
| 2007 |
He JQ, January CT, Thomson JA, Kamp TJ. Human embryonic stem cell-derived cardiomyocytes: drug discovery and safety pharmacology. Expert Opinion On Drug Discovery. 2: 739-53. PMID 23488962 DOI: 10.1517/17460441.2.5.739 |
0.312 |
|
| 2007 |
Balijepalli RC, Delisle BP, Balijepalli SY, Foell JD, Slind JK, Kamp TJ, January CT. Kv11.1 (ERG1) K+ channels localize in cholesterol and sphingolipid enriched membranes and are modulated by membrane cholesterol. Channels (Austin, Tex.). 1: 263-72. PMID 18708743 DOI: 10.4161/Chan.4946 |
0.665 |
|
| 2007 |
Lehnart SE, Ackerman MJ, Benson DW, Brugada R, Clancy CE, Donahue JK, George AL, Grant AO, Groft SC, January CT, Lathrop DA, Lederer WJ, Makielski JC, Mohler PJ, Moss A, et al. Inherited arrhythmias: a National Heart, Lung, and Blood Institute and Office of Rare Diseases workshop consensus report about the diagnosis, phenotyping, molecular mechanisms, and therapeutic approaches for primary cardiomyopathies of gene mutations affecting ion channel function. Circulation. 116: 2325-45. PMID 17998470 DOI: 10.1161/Circulationaha.107.711689 |
0.423 |
|
| 2006 |
Rajamani S, Eckhardt LL, Valdivia CR, Klemens CA, Gillman BM, Anderson CL, Holzem KM, Delisle BP, Anson BD, Makielski JC, January CT. Drug-induced long QT syndrome: hERG K+ channel block and disruption of protein trafficking by fluoxetine and norfluoxetine. British Journal of Pharmacology. 149: 481-9. PMID 16967046 DOI: 10.1038/Sj.Bjp.0706892 |
0.72 |
|
| 2006 |
Robertson GA, January CT. HERG trafficking and pharmacological rescue of LQTS-2 mutant channels. Handbook of Experimental Pharmacology. 349-55. PMID 16610352 DOI: 10.1007/3-540-29715-4-14 |
0.475 |
|
| 2006 |
Anderson CL, Delisle BP, Anson BD, Kilby JA, Will ML, Tester DJ, Gong Q, Zhou Z, Ackerman MJ, January CT. Most LQT2 mutations reduce Kv11.1 (hERG) current by a class 2 (trafficking-deficient) mechanism. Circulation. 113: 365-73. PMID 16432067 DOI: 10.1161/Circulationaha.105.570200 |
0.735 |
|
| 2006 |
Kawakami K, Nagatomo T, Abe H, Kikuchi K, Takemasa H, Anson BD, Delisle BP, January CT, Nakashima Y. Comparison of HERG channel blocking effects of various beta-blockers-- implication for clinical strategy. British Journal of Pharmacology. 147: 642-52. PMID 16314852 DOI: 10.1038/Sj.Bjp.0706508 |
0.65 |
|
| 2006 |
Rajamani S, Anderson CL, Valdivia CR, Eckhardt LL, Foell JD, Robertson GA, Kamp TJ, Makielski JC, Anson BD, January CT. Specific serine proteases selectively damage KCNH2 (hERG1) potassium channels and I(Kr). American Journal of Physiology. Heart and Circulatory Physiology. 290: H1278-88. PMID 16227340 DOI: 10.1152/Ajpheart.00777.2005 |
0.501 |
|
| 2006 |
Delisle BP, Underkofler HA, Anderson CL, January CT. AB1-4 Heart Rhythm. 3: S2. DOI: 10.1016/J.Hrthm.2006.02.025 |
0.542 |
|
| 2005 |
Delisle BP, Slind JK, Kilby JA, Anderson CL, Anson BD, Balijepalli RC, Tester DJ, Ackerman MJ, Kamp TJ, January CT. Intragenic suppression of trafficking-defective KCNH2 channels associated with long QT syndrome. Molecular Pharmacology. 68: 233-40. PMID 15851652 DOI: 10.1124/Mol.105.012914 |
0.732 |
|
| 2005 |
Kikuchi K, Nagatomo T, Abe H, Kawakami K, Duff HJ, Makielski JC, January CT, Nakashima Y. Blockade of HERG cardiac K+ current by antifungal drug miconazole. British Journal of Pharmacology. 144: 840-8. PMID 15778703 DOI: 10.1038/Sj.Bjp.0706095 |
0.502 |
|
| 2005 |
Anson BD, Weaver JG, Ackerman MJ, Akinsete O, Henry K, January CT, Badley AD. Blockade of HERG channels by HIV protease inhibitors. Lancet (London, England). 365: 682-6. PMID 15721475 DOI: 10.1016/S0140-6736(05)17950-1 |
0.413 |
|
| 2005 |
Eckhardt LL, Rajamani S, January CT. Protein trafficking abnormalities: a new mechanism in drug-induced long QT syndrome. British Journal of Pharmacology. 145: 3-4. PMID 15711590 DOI: 10.1038/Sj.Bjp.0706143 |
0.456 |
|
| 2005 |
Anson BAD, Lian J, Cui C, Xue X, Zhang L, Huang C, Ma A, Vincent GM, January CT. Molecular, cellular, and functional analysis of a novel long QT type 2 deletion Heart Rhythm. 2: S295. DOI: 10.1016/J.Hrthm.2005.02.928 |
0.316 |
|
| 2005 |
Delisle BP, Anderson CL, Anson BD, Kilby JA, Will ML, Tester DJ, Ackerman MJ, Gong Q, Zhou Z, January CT. Most LQT-linked KCNH2 mutations are trafficking-defective Heart Rhythm. 2: S175-S176. DOI: 10.1016/J.Hrthm.2005.02.547 |
0.659 |
|
| 2005 |
Rajamani S, Kilby J, Slind J, Balijepalli RC, Anderson CL, Anson BD, Kamp TJ, January CT. N-linked glycosylation is not obligatory for rescue of trafficking-defective LQT2 mutations Heart Rhythm. 2: S107. DOI: 10.1016/J.Hrthm.2005.02.333 |
0.389 |
|
| 2004 |
Zhang L, Vincent GM, Baralle M, Baralle FE, Anson BD, Benson DW, Whiting B, Timothy KW, Carlquist J, January CT, Keating MT, Splawski I. An intronic mutation causes long QT syndrome. Journal of the American College of Cardiology. 44: 1283-91. PMID 15364333 DOI: 10.1016/J.Jacc.2004.06.045 |
0.407 |
|
| 2004 |
Delisle BP, Anson BD, Rajamani S, January CT. Biology of cardiac arrhythmias: ion channel protein trafficking. Circulation Research. 94: 1418-28. PMID 15192037 DOI: 10.1161/01.Res.0000128561.28701.Ea |
0.678 |
|
| 2004 |
Gong Q, Anderson CL, January CT, Zhou Z. Pharmacological rescue of trafficking defective HERG channels formed by coassembly of wild-type and long QT mutant N470D subunits. American Journal of Physiology. Heart and Circulatory Physiology. 287: H652-8. PMID 15072950 DOI: 10.1152/Ajpheart.00052.2004 |
0.53 |
|
| 2004 |
Anson BD, Ackerman MJ, Tester DJ, Will ML, Delisle BP, Anderson CL, January CT. Molecular and functional characterization of common polymorphisms in HERG (KCNH2) potassium channels. American Journal of Physiology. Heart and Circulatory Physiology. 286: H2434-41. PMID 14975928 DOI: 10.1152/Ajpheart.00891.2003 |
0.705 |
|
| 2004 |
Foell JD, Balijepalli RC, Delisle BP, Yunker AM, Robia SL, Walker JW, McEnery MW, January CT, Kamp TJ. Molecular heterogeneity of calcium channel beta-subunits in canine and human heart: evidence for differential subcellular localization. Physiological Genomics. 17: 183-200. PMID 14762176 DOI: 10.1152/Physiolgenomics.00207.2003 |
0.592 |
|
| 2004 |
Kamp TJ, January CT. Inherited and acquired long QT syndromes: New insights and evolving technology Drug Discovery Today: Disease Mechanisms. 1: 45-51. DOI: 10.1016/J.Ddmec.2004.08.014 |
0.423 |
|
| 2004 |
Makielski JC, Ye B, Kamp TJ, January CT. Pharmacology of the Cardiac Sodium Channel Cardiac Electrophysiology: Fourth Edition. 127-132. DOI: 10.1016/B0-7216-0323-8/50018-X |
0.311 |
|
| 2003 |
Bisinov E, Mitchell JH, January CT. Potassium and Long QT Syndrome: A New Look at an Old Therapy Journal of the American College of Cardiology. 42: 1783-1784. PMID 14642688 DOI: 10.1016/J.Jacc.2003.08.015 |
0.301 |
|
| 2003 |
Delisle BP, Anderson CL, Balijepalli RC, Anson BD, Kamp TJ, January CT. Thapsigargin selectively rescues the trafficking defective LQT2 channels G601S and F805C. The Journal of Biological Chemistry. 278: 35749-54. PMID 12837749 DOI: 10.1074/Jbc.M305787200 |
0.741 |
|
| 2002 |
Roti EC, Myers CD, Ayers RA, Boatman DE, Delfosse SA, Chan EK, Ackerman MJ, January CT, Robertson GA. Interaction with GM130 during HERG ion channel trafficking. Disruption by type 2 congenital long QT syndrome mutations. Human Ether-Ã -go-go-Related Gene. The Journal of Biological Chemistry. 277: 47779-85. PMID 12270925 DOI: 10.1074/Jbc.M206638200 |
0.504 |
|
| 2002 |
Mbai M, Rajamani S, January CT. The anti-malarial drug halofantrine and its metabolite N-desbutylhalofantrine block HERG potassium channels. Cardiovascular Research. 55: 799-805. PMID 12176129 DOI: 10.1016/S0008-6363(02)00448-0 |
0.416 |
|
| 2002 |
Mbai M, Rajamani S, Delisle BP, Anson BD, Anderson C, Makielski JC, January CT. Genetic basis for the origin of cardiac arrhythmias: implications for therapy. Current Cardiology Reports. 4: 411-7. PMID 12169238 DOI: 10.1007/S11886-002-0041-5 |
0.593 |
|
| 2002 |
Rajamani S, Anderson CL, Anson BD, January CT. Pharmacological rescue of human K(+) channel long-QT2 mutations: human ether-a-go-go-related gene rescue without block. Circulation. 105: 2830-5. PMID 12070109 DOI: 10.1161/01.Cir.0000019513.50928.74 |
0.558 |
|
| 2002 |
Gong Q, Anderson CL, January CT, Zhou Z. Role of glycosylation in cell surface expression and stability of HERG potassium channels. American Journal of Physiology. Heart and Circulatory Physiology. 283: H77-84. PMID 12063277 DOI: 10.1152/Ajpheart.00008.2002 |
0.442 |
|
| 2002 |
Nagatomo T, January CT, Ye B, Abe H, Nakashima Y, Makielski JC. Rate-dependent QT shortening mechanism for the LQT3 deltaKPQ mutant. Cardiovascular Research. 54: 624-9. PMID 12031708 DOI: 10.1016/S0008-6363(02)00265-1 |
0.474 |
|
| 2002 |
Delisle B, Anderson C, January CT. 06 E4031 Rescue of HERG does not require the restoration of N-linked glycosyoltion Journal of Molecular and Cellular Cardiology. 34: A18. DOI: 10.1016/S0022-2828(02)90135-5 |
0.574 |
|
| 2001 |
Zhang S, Rajamani S, Chen Y, Gong Q, Rong Y, Zhou Z, Ruoho A, January CT. Cocaine blocks HERG, but not KvLQT1+minK, potassium channels. Molecular Pharmacology. 59: 1069-76. PMID 11306689 DOI: 10.1124/Mol.59.5.1069 |
0.35 |
|
| 2001 |
Studenik CR, Zhou Z, January CT. Differences in action potential and early afterdepolarization properties in LQT2 and LQT3 models of long QT syndrome British Journal of Pharmacology. 132: 85-92. PMID 11156564 DOI: 10.1038/Sj.Bjp.0703770 |
0.362 |
|
| 2000 |
January CT, Gong Q, Zhou Z. Long QT syndrome: Cellular basis and arrhythmia mechanism in LQT2 Journal of Cardiovascular Electrophysiology. 11: 1413-1418. PMID 11196567 DOI: 10.1046/J.1540-8167.2000.01413.X |
0.568 |
|
| 2000 |
January CT. Proarrhythmia related to prolongation of repolarization: Mechanisms, monitoring, prevention, and management Cardiac Electrophysiology Review. 4: 212-216. DOI: 10.1023/A:1009963228964 |
0.447 |
|
| 2000 |
January CT, Gong Q, Zhou Z. Defective protein trafficking of HERG K+ channels in human congenital long QT syndrome Pharmaceutical News. 7: 27-34. |
0.456 |
|
| 1999 |
Zhou Z, Gong Q, January CT. Correction of defective protein trafficking of a mutant HERG potassium channel in human long QT syndrome. Pharmacological and temperature effects Journal of Biological Chemistry. 274: 31123-31126. PMID 10531299 DOI: 10.1074/Jbc.274.44.31123 |
0.528 |
|
| 1999 |
Zhou Z, Vorperian VR, Gong Q, Zhang S, January CT. Block of HERG potassium channels by the antihistamine astemizole and its metabolites desmethylastemizole and norastemizole Journal of Cardiovascular Electrophysiology. 10: 836-843. PMID 10376921 DOI: 10.1111/J.1540-8167.1999.Tb00264.X |
0.462 |
|
| 1999 |
Zhang S, Zhou Z, Gong Q, Makielski JC, January CT. Mechanism of block and identification of the verapamil binding domain to HERG potassium channels Circulation Research. 84: 989-998. PMID 10325236 DOI: 10.1161/01.Res.84.9.989 |
0.511 |
|
| 1999 |
Furutani M, Trudeau MC, Hagiwara N, Seki A, Gong Q, Zhou Z, Imamura S, Nagashima H, Kasanuki H, Takao A, Momma K, January CT, Robertson GA, Matsuoka R. Novel mechanism associated with an inherited cardiac arrhythmia: defective protein trafficking by the mutant HERG (G601S) potassium channel. Circulation. 99: 2290-4. PMID 10226095 DOI: 10.1161/01.Cir.99.17.2290 |
0.561 |
|
| 1998 |
Nagatomo T, Fan Z, Ye B, Tonkovich GS, January CT, Kyle JW, Makielski JC. Temperature dependence of early and late currents in human cardiac wild-type and long Q-T ΔKPQ Nachannels. American Journal of Physiology. Heart and Circulatory Physiology. 275: H2016-H2024. PMID 29586760 DOI: 10.1152/ajpheart.1998.275.6.H2016 |
0.321 |
|
| 1998 |
Nagatomo T, Fan Z, Ye B, Tonkovich GS, January CT, Kyle JW, Makielski JC. Temperature dependence of early and late currents in human cardiac wild- type and long Q-T ΔKPQ Na+ channels American Journal of Physiology - Heart and Circulatory Physiology. 275. PMID 9843800 DOI: 10.1152/Ajpheart.1998.275.6.H2016 |
0.447 |
|
| 1998 |
Zhou Z, Gong Q, Epstein ML, January CT. HERG channel dysfunction in human long QT syndrome. Intracellular transport and functional defects Journal of Biological Chemistry. 273: 21061-21066. PMID 9694858 DOI: 10.1074/Jbc.273.33.21061 |
0.567 |
|
| 1998 |
Taglialatela M, Pannaccione A, Castaldo P, Giorgio G, Zhou Z, January CT, Genovese A, Marone G, Annunziato L. Molecular basis for the lack of HERG K+ channel block-related cardiotoxicity by the H1 receptor blocker cetirizine compared with other second-generation antihistamines Molecular Pharmacology. 54: 113-121. PMID 9658196 |
0.342 |
|
| 1998 |
Zhou Z, January CT. Both T- and L-type Ca2+ channels can contribute to excitation- contraction coupling in cardiac Purkinje cells Biophysical Journal. 74: 1830-1839. PMID 9545045 DOI: 10.1016/S0006-3495(98)77893-2 |
0.339 |
|
| 1998 |
Zhou Z, Gong Q, Ye B, Fan Z, Makielski JC, Robertson GA, January CT. Properties of HERG channels stably expressed in HEK 293 cells studied at physiological temperature. Biophysical Journal. 74: 230-41. PMID 9449325 DOI: 10.1016/S0006-3495(98)77782-3 |
0.437 |
|
| 1998 |
Nagatomo T, Fan Z, Ye B, Tonkovich GS, January CT, Kyle JW, Makielski JC. Temperature dependence of early and late currents in human cardiac wild-type and long Q-T ΔKPQ Na+ channels American Journal of Physiology - Heart and Circulatory Physiology. 44. |
0.359 |
|
| 1997 |
Mohammad S, Zhou Z, Gong Q, January CT. Blockage of the HERG human cardiac Kchannel by the gastrointestinal prokinetic agent cisapride. American Journal of Physiology. Heart and Circulatory Physiology. 273: H2534-H2538. PMID 29586481 DOI: 10.1152/ajpheart.1997.273.5.H2534 |
0.369 |
|
| 1997 |
Mohammad S, Zhou Z, Gong Q, January CT. Blockage of the HERG human cardiac K+ channel by the gastrointestinal prokinetic agent cisapride American Journal of Physiology - Heart and Circulatory Physiology. 273. PMID 9374794 DOI: 10.1152/Ajpheart.1997.273.5.H2534 |
0.485 |
|
| 1996 |
Vorperian VR, Zhou Z, Mohammad S, Hoon TJ, Studenik C, January CT. Torsade de pointes with an antihistamine metabolite: Potassium channel blockade with desmethylastemizole Journal of the American College of Cardiology. 28: 1556-1561. PMID 8917271 DOI: 10.1016/S0735-1097(96)00352-X |
0.406 |
|
| 1995 |
Xie JT, Cunningham PM, January CT. 771-4 Enhancement of Delayed Afterdepolarlzatlons (DADs) and Triggered Activity by E-4031 and Dofetilide In a Cardiac Glycoside Model of Cell Ca 2+ Overload Journal of the American College of Cardiology. 25: 284A-285A. DOI: 10.1016/0735-1097(95)92640-Q |
0.308 |
|
| 1992 |
January CT, Cadman C, Shorofsky S. Mechanisms of triggered arrhythmias Coronary Artery Disease. 3: 339-344. DOI: 10.1097/00019501-199204000-00012 |
0.343 |
|
| 1991 |
January CT, Chau V, Makielski JC. Triggered activity in the heart: cellular mechanisms of early after-depolarizations. European Heart Journal. 12: 4-9. PMID 1725155 |
0.327 |
|
| 1990 |
Hirano Y, Moscucci A, January CT. Direct measurement of L-type Ca2+ window current in heart cells Circulation Research. 70: 445-455. PMID 1371428 DOI: 10.1161/01.Res.70.3.445 |
0.404 |
|
| 1990 |
Shorofsky SR, January CT. L- and T-type Ca2+ channels in canine cardiac purkinje cells: Single-channel demonstration of L-type Ca2+ window current Circulation Research. 70: 456-464. PMID 1311220 DOI: 10.1161/01.Res.70.3.456 |
0.402 |
|
| 1990 |
January CT, Shorofsky S. Early afterdepolarizations: newer insights into cellular mechanisms Journal of Cardiovascular Electrophysiology. 1: 161-169. DOI: 10.1111/J.1540-8167.1990.Tb01058.X |
0.359 |
|
| 1989 |
January CT, Riddle JM. Early afterdepolarizations: mechanism of induction and block. A role for L-type Ca2+ current. Circulation Research. 64: 977-90. PMID 2468430 DOI: 10.1161/01.Res.64.5.977 |
0.362 |
|
| 1987 |
Makielski JC, Sheets MF, Hanck DA, January CT, Fozzard HA. Sodium current in voltage clamped internally perfused canine cardiac Purkinje cells. Biophysical Journal. 52: 1-11. PMID 3607218 DOI: 10.1016/S0006-3495(87)83182-X |
0.377 |
|
| 1986 |
Chapman RA, Fozzard HA, Friedlander IR, January CT. Effects of Ca2+/Mg2+ removal on aiNa, aiK, and tension in cardiac Purkinje fibers. The American Journal of Physiology. 251: C920-7. PMID 3789132 DOI: 10.1152/Ajpcell.1986.251.6.C920 |
0.317 |
|
| 1986 |
Fozzard HA, Friedlander IR, Hanck DA, January CT, Makielski JC, Sheets MF. Sodium currents in single cardiac Purkinje cells. Journal of the American College of Cardiology. 8: 79A-85A. PMID 2423574 DOI: 10.1016/S0735-1097(86)80033-X |
0.454 |
|
| 1985 |
Fozzard HA, January CT, Makielski JC. New studies of the excitatory sodium currents in heart muscle Circulation Research. 56: 475-485. PMID 2579746 DOI: 10.1161/01.Res.56.4.475 |
0.451 |
|
| 1983 |
Sheets MF, January CT, Fozzard HA. Isolation and characterization of single canine cardiac purkinje cells. Circulation Research. 53: 544-8. PMID 6627612 DOI: 10.1161/01.Res.53.4.544 |
0.317 |
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