Paula J. Grabowski - Publications

Affiliations: 
University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Molecular Biology, Biochemistry

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Dembowski JA, An P, Scoulos-Hanson M, Yeo G, Han J, Fu XD, Grabowski PJ. Alternative Splicing of a Novel Inducible Exon Diversifies the CASK Guanylate Kinase Domain. Journal of Nucleic Acids. 2012: 816237. PMID 23008758 DOI: 10.1155/2012/816237  0.602
2011 Grabowski P. Alternative splicing takes shape during neuronal development. Current Opinion in Genetics & Development. 21: 388-94. PMID 21511457 DOI: 10.1016/J.Gde.2011.03.005  0.509
2009 Dembowski JA, Grabowski PJ. The CUGBP2 splicing factor regulates an ensemble of branchpoints from perimeter binding sites with implications for autoregulation. Plos Genetics. 5: e1000595. PMID 19680430 DOI: 10.1371/Journal.Pgen.1000595  0.605
2007 Grabowski PJ. RNA-binding proteins switch gears to drive alternative splicing in neurons. Nature Structural & Molecular Biology. 14: 577-9. PMID 17611596 DOI: 10.1038/Nsmb0707-577  0.496
2007 An P, Grabowski PJ. Exon silencing by UAGG motifs in response to neuronal excitation. Plos Biology. 5: e36. PMID 17298175 DOI: 10.1371/Journal.Pbio.0050036  0.546
2005 Grabowski PJ. Splicing-active nuclear extracts from rat brain. Methods (San Diego, Calif.). 37: 323-30. PMID 16314261 DOI: 10.1016/J.Ymeth.2005.07.014  0.507
2005 Xu XM, Mix H, Carlson BA, Grabowski PJ, Gladyshev VN, Berry MJ, Hatfield DL. Evidence for direct roles of two additional factors, SECp43 and soluble liver antigen, in the selenoprotein synthesis machinery. The Journal of Biological Chemistry. 280: 41568-75. PMID 16230358 DOI: 10.1074/Jbc.M506696200  0.4
2005 Han K, Yeo G, An P, Burge CB, Grabowski PJ. A combinatorial code for splicing silencing: UAGG and GGGG motifs. Plos Biology.. 3: e158. PMID 15828859 DOI: 10.1371/Journal.Pbio.0030158  0.581
2004 Grabowski PJ. A molecular code for splicing silencing: configurations of guanosine-rich motifs. Biochemical Society Transactions. 32: 924-7. PMID 15506926 DOI: 10.1042/Bst0320924  0.568
2003 Miné M, Brivet M, Touati G, Grabowski P, Abitbol M, Marsac C. Splicing error in E1alpha pyruvate dehydrogenase mRNA caused by novel intronic mutation responsible for lactic acidosis and mental retardation. The Journal of Biological Chemistry. 278: 11768-72. PMID 12551913 DOI: 10.1074/jbc.M211106200  0.399
2003 Black DL, Grabowski PJ. Alternative pre-mRNA splicing and neuronal function. Progress in Molecular and Subcellular Biology. 31: 187-216. PMID 12494767 DOI: 10.1007/978-3-662-09728-1_7  0.591
2002 Zhang W, Liu H, Han K, Grabowski PJ. Region-specific alternative splicing in the nervous system: implications for regulation by the RNA-binding protein NAPOR. Rna (New York, N.Y.). 8: 671-85. PMID 12022233 DOI: 10.1017/S1355838202027036  0.607
2002 Grabowski P. Alternative splicing in parallel. Nature Biotechnology. 20: 346-7. PMID 11923836 DOI: 10.1038/Nbt0402-346  0.392
2002 Wu JI, Reed RB, Grabowski PJ, Artzt K. Function of quaking in myelination: regulation of alternative splicing. Proceedings of the National Academy of Sciences of the United States of America. 99: 4233-8. PMID 11917126 DOI: 10.1073/Pnas.072090399  0.589
2002 Liu H, Zhang W, Reed RB, Liu W, Grabowski PJ. Mutations in RRM4 uncouple the splicing repression and RNA-binding activities of polypyrimidine tract binding protein. Rna (New York, N.Y.). 8: 137-49. PMID 11911361 DOI: 10.1017/S1355838202015029  0.538
2001 Grabowski PJ, Black DL. Alternative RNA splicing in the nervous system. Progress in Neurobiology. 65: 289-308. PMID 11473790 DOI: 10.1016/S0301-0082(01)00007-7  0.564
2000 Grabowski PJ. Genetic evidence for a Nova regulator of alternative splicing in the brain. Neuron. 25: 254-6. PMID 10719879 DOI: 10.1016/S0896-6273(00)80888-0  0.318
1999 Ding F, Grabowski PJ. Identification of a protein component of a mammalian tRNA(Sec) complex implicated in the decoding of UGA as selenocysteine. Rna (New York, N.Y.). 5: 1561-9. PMID 10606267 DOI: 10.1017/S1355838299991598  0.478
1999 Zhang L, Liu W, Grabowski PJ. Coordinate repression of a trio of neuron-specific splicing events by the splicing regulator PTB. Rna (New York, N.Y.). 5: 117-30. PMID 9917071 DOI: 10.1017/S1355838299981530  0.619
1998 Grabowski PJ. Splicing regulation in neurons: tinkering with cell-specific control. Cell. 92: 709-12. PMID 9529247 DOI: 10.1016/S0092-8674(00)81399-9  0.433
1997 Ashiya M, Grabowski PJ. A neuron-specific splicing switch mediated by an array of pre-mRNA repressor sites: evidence of a regulatory role for the polypyrimidine tract binding protein and a brain-specific PTB counterpart. Rna (New York, N.Y.). 3: 996-1015. PMID 9292499  0.564
1996 Wang Z, Grabowski PJ. Cell- and stage-specific splicing events resolved in specialized neurons of the rat cerebellum. Rna (New York, N.Y.). 2: 1241-53. PMID 8972773  0.427
1996 Zhang L, Ashiya M, Sherman TG, Grabowski PJ. Essential nucleotides direct neuron-specific splicing of gamma 2 pre-mRNA. Rna (New York, N.Y.). 2: 682-98. PMID 8756411  0.575
1996 Ding F, Hagan JP, Wang Z, Grabowski PJ. Biochemical properties of a novel U2AF65 protein isoform generated by alternative RNA splicing. Biochemical and Biophysical Research Communications. 224: 675-83. PMID 8713106 DOI: 10.1006/Bbrc.1996.1083  0.532
1995 Cunningham TP, Hagan JP, Grabowski PJ. Reconstitution of exon-bridging activity with purified U2AF and U1 snRNP components. Nucleic Acids Symposium Series. 218-9. PMID 8643375  0.42
1995 Ashiya M, Zhang L, Grabowski PJ. Regulated splicing of gamma2 pre-messenger RNA in neuronal cells. Nucleic Acids Symposium Series. 215-6. PMID 8643374  0.428
1995 Wang Z, Hoffmann HM, Grabowski PJ. Intrinsic U2AF binding is modulated by exon enhancer signals in parallel with changes in splicing activity. Rna (New York, N.Y.). 1: 21-35. PMID 7489484  0.468
1992 Hoffman BE, Grabowski PJ. U1 snRNP targets an essential splicing factor, U2AF65, to the 3' splice site by a network of interactions spanning the exon. Genes & Development. 6: 2554-68. PMID 1285125  0.481
1991 Grabowski PJ, Nasim FU, Kuo HC, Burch R. Combinatorial splicing of exon pairs by two-site binding of U1 small nuclear ribonucleoprotein particle. Molecular and Cellular Biology. 11: 5919-28. PMID 1834932  0.436
1991 Kuo HC, Nasim FH, Grabowski PJ. Control of alternative splicing by the differential binding of U1 small nuclear ribonucleoprotein particle. Science (New York, N.Y.). 251: 1045-50. PMID 1825520  0.395
1990 Nasim FH, Spears PA, Hoffmann HM, Kuo HC, Grabowski PJ. A Sequential splicing mechanism promotes selection of an optimal exon by repositioning a downstream 5' splice site in preprotachykinin pre-mRNA. Genes & Development. 4: 1172-84. PMID 2210374  0.463
1988 Lamond AI, Konarska MM, Grabowski PJ, Sharp PA. Spliceosome assembly involves the binding and release of U4 small nuclear ribonucleoprotein. Proceedings of the National Academy of Sciences of the United States of America. 85: 411-5. PMID 2963332 DOI: 10.1073/Pnas.85.2.411  0.346
1986 Grabowski PJ, Sharp PA. Affinity chromatography of splicing complexes: U2, U5, and U4 + U6 small nuclear ribonucleoprotein particles in the spliceosome. Science (New York, N.Y.). 233: 1294-9. PMID 3638792 DOI: 10.1126/Science.3638792  0.394
1986 Padgett RA, Grabowski PJ, Konarska MM, Seiler S, Sharp PA. Splicing of messenger RNA precursors. Annual Review of Biochemistry. 55: 1119-50. PMID 2943217 DOI: 10.1146/Annurev.Bi.55.070186.005351  0.41
1985 Grabowski PJ, Seiler SR, Sharp PA. A multicomponent complex is involved in the splicing of messenger RNA precursors. Cell. 42: 345-53. PMID 3160482 DOI: 10.1016/S0092-8674(85)80130-6  0.317
1985 Konarska MM, Grabowski PJ, Padgett RA, Sharp PA. Characterization of the branch site in lariat RNAs produced by splicing of mRNA precursors. Nature. 313: 552-7. PMID 2578627 DOI: 10.1038/313552A0  0.43
1985 Padgett RA, Grabowski PJ, Konarska MM, Sharp PA. Splicing messenger RNA precursors: branch sites and lariat RNAs Trends in Biochemical Sciences. 10: 154-157. DOI: 10.1016/0968-0004(85)90156-2  0.368
1984 Grabowski PJ, Padgett RA, Sharp PA. Messenger RNA splicing in vitro: an excised intervening sequence and a potential intermediate. Cell. 37: 415-27. PMID 6722880 DOI: 10.1016/0092-8674(84)90372-6  0.427
1984 Hardy SF, Grabowski PJ, Padgett RA, Sharp PA. Cofactor requirements of splicing of purified messenger RNA precursors. Nature. 308: 375-7. PMID 6709044 DOI: 10.1038/308375A0  0.403
1984 Padgett RA, Konarska MM, Grabowski PJ, Hardy SF, Sharp PA. Lariat RNA's as intermediates and products in the splicing of messenger RNA precursors. Science (New York, N.Y.). 225: 898-903. PMID 6206566 DOI: 10.1126/Science.6206566  0.42
1983 Zaug AJ, Grabowski PJ, Cech TR. Autocatalytic cyclization of an excised intervening sequence RNA is a cleavage-ligation reaction. Nature. 301: 578-83. PMID 6186917 DOI: 10.1038/301578A0  0.3
1982 Kruger K, Grabowski PJ, Zaug AJ, Sands J, Gottschling DE, Cech TR. Self-splicing RNA: autoexcision and autocyclization of the ribosomal RNA intervening sequence of Tetrahymena. Cell. 31: 147-57. PMID 6297745 DOI: 10.1016/0092-8674(82)90414-7  0.335
1981 Cech TR, Zaug AJ, Grabowski PJ. In vitro splicing of the ribosomal RNA precursor of Tetrahymena: involvement of a guanosine nucleotide in the excision of the intervening sequence. Cell. 27: 487-96. PMID 6101203 DOI: 10.1016/0092-8674(81)90390-1  0.344
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