| Year |
Citation |
Score |
| 2023 |
Hossain F, Ucar DA, Monticone G, Ran Y, Majumder S, Larter K, Luu H, Wyczechowska D, Heidari S, Xu K, Shanthalingam S, Matossian M, Xi Y, Burow M, Collins-Burow B, ... ... Miele L, et al. Sulindac sulfide as a non-immune suppressive γ-secretase modulator to target triple-negative breast cancer. Frontiers in Immunology. 14: 1244159. PMID 37901240 DOI: 10.3389/fimmu.2023.1244159 |
0.383 |
|
| 2022 |
Monticone G, Huang Z, Csibi F, Leit S, Ciccone D, Champhekar AS, Austin JE, Ucar DA, Hossain F, Ibba SV, Boulares AH, Carpino N, Xu K, Majumder S, Osborne BA, ... ... Miele L, et al. Targeting the Cbl-b-Notch1 axis as a novel immunotherapeutic strategy to boost CD8+ T-cell responses. Frontiers in Immunology. 13: 987298. PMID 36090975 DOI: 10.3389/fimmu.2022.987298 |
0.303 |
|
| 2022 |
Perrone C, Pomella S, Cassandri M, Pezzella M, Milano GM, Colletti M, Cossetti C, Pericoli G, Di Giannatale A, de Billy E, Vinci M, Petrini S, Marampon F, Quintarelli C, Taulli R, ... ... Miele L, et al. MET Inhibition Sensitizes Rhabdomyosarcoma Cells to NOTCH Signaling Suppression. Frontiers in Oncology. 12: 835642. PMID 35574376 DOI: 10.3389/fonc.2022.835642 |
0.426 |
|
| 2021 |
Hoang VT, Matossian MD, La J, Hoang K, Ucar DA, Elliott S, Burks HE, Wright TD, Patel S, Bhatt A, Phamduy T, Chrisey D, Buechlein A, Rusch DB, Nephew KP, ... ... Miele L, et al. Dual inhibition of MEK1/2 and MEK5 suppresses the EMT/migration axis in triple-negative breast cancer through FRA-1 regulation. Journal of Cellular Biochemistry. PMID 33876843 DOI: 10.1002/jcb.29916 |
0.427 |
|
| 2021 |
Bhatt AB, Wright TD, Barnes V, Chakrabarty S, Matossian MD, Lexner E, Ucar DA, Miele L, Flaherty PT, Burow ME, Cavanaugh JE. Diverse and converging roles of ERK1/2 and ERK5 pathways on mesenchymal to epithelial transition in breast cancer. Translational Oncology. 14: 101046. PMID 33761370 DOI: 10.1016/j.tranon.2021.101046 |
0.429 |
|
| 2021 |
Bhatt AB, Patel S, Matossian MD, Ucar DA, Miele L, Burow ME, Flaherty PT, Cavanaugh JE. Molecular Mechanisms of Epithelial to Mesenchymal Transition Regulated by ERK5 Signaling. Biomolecules. 11. PMID 33572742 DOI: 10.3390/biom11020183 |
0.368 |
|
| 2021 |
Monticone G, Miele L. Notch Pathway: A Journey from Notching Phenotypes to Cancer Immunotherapy. Advances in Experimental Medicine and Biology. 1287: 201-222. PMID 33034034 DOI: 10.1007/978-3-030-55031-8_13 |
0.305 |
|
| 2020 |
Majumder S, Crabtree JS, Golde TE, Minter LM, Osborne BA, Miele L. Targeting Notch in oncology: the path forward. Nature Reviews. Drug Discovery. PMID 33293690 DOI: 10.1038/s41573-020-00091-3 |
0.376 |
|
| 2020 |
Chang TC, Matossian MD, Elliott S, Burks HE, Sabol RA, Ucar DA, Wathieu H, Zabaleta J, Valle L, Gill S, Martin E, Riker AI, Miele L, Bunnell BA, Burow ME, et al. Evaluation of deacetylase inhibition in metaplastic breast carcinoma using multiple derivations of preclinical models of a new patient-derived tumor. Plos One. 15: e0226464. PMID 33035223 DOI: 10.1371/journal.pone.0226464 |
0.393 |
|
| 2020 |
Hoang VT, Matossian MD, Ucar DA, Elliott S, La J, Wright MK, Burks HE, Perles A, Hossain F, King CT, Browning VE, Bursavich J, Fang F, Del Valle L, Bhatt AB, ... ... Miele L, et al. ERK5 Is Required for Tumor Growth and Maintenance Through Regulation of the Extracellular Matrix in Triple Negative Breast Cancer. Frontiers in Oncology. 10: 1164. PMID 32850332 DOI: 10.3389/Fonc.2020.01164 |
0.496 |
|
| 2020 |
Matossian MD, Burks HE, Elliott S, Hoang VT, Zuercher WJ, Wells C, Drewry DH, Kapadia N, Chang T, Yan T, Windsor GO, Nguyen K, Fang F, Nephew KP, Buechlein A, ... ... Miele L, et al. A novel screening approach comparing kinase activity of small molecule inhibitors with similar molecular structures and distinct biologic effects in triple-negative breast cancer to identify targetable signaling pathways. Anti-Cancer Drugs. 31: 759-775. PMID 32796402 DOI: 10.1097/Cad.0000000000000962 |
0.358 |
|
| 2020 |
Mitra A, Shanthalingam S, Sherman HL, Singh K, Canakci M, Torres JA, Lawlor R, Ran Y, Golde TE, Miele L, Thayumanavan S, Minter LM, Osborne BA. CD28 Signaling Drives Notch Ligand Expression on CD4 T Cells. Frontiers in Immunology. 11: 735. PMID 32457739 DOI: 10.3389/Fimmu.2020.00735 |
0.424 |
|
| 2020 |
Matossian M, Elliott S, Wright M, Chang T, Alzoubi M, Wathieu H, Sabol R, Alfortish A, Burks H, Hoang V, Ucar D, Windsor G, Yan T, Zabaleta J, Hossain F, ... ... Miele L, et al. Abstract P6-03-17: Effect of histone deacetylase inhibitors on patient-derived neoadjuvant chemotherapy resistant triple negative breast cancer xenografts that represent understudied patients Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P6-03-17 |
0.439 |
|
| 2020 |
Monticone G, Hossain FM, Ucar DA, Majumder S, Sorrentino C, Rodriguez PC, Sierra RA, Pannuti A, Hatfield S, Osborne BA, Minter LM, Morello S, Miele L. Abstract 4517: Targeting Notch1 via adenosine A2A receptor to modulate tumor immunity Immunology. 80: 4517-4517. DOI: 10.1158/1538-7445.Am2020-4517 |
0.455 |
|
| 2019 |
Yedjou CG, Sims JN, Miele L, Noubissi F, Lowe L, Fonseca DD, Alo RA, Payton M, Tchounwou PB. Health and Racial Disparity in Breast Cancer. Advances in Experimental Medicine and Biology. 1152: 31-49. PMID 31456178 DOI: 10.1007/978-3-030-20301-6_3 |
0.361 |
|
| 2019 |
Lessard CB, Rodriguez E, Ladd TB, Minter LM, Osborne BA, Miele L, Golde TE, Ran Y. Individual and combined presenilin 1 and 2 knockouts reveal that both have highly overlapping functions in HEK293T cells. The Journal of Biological Chemistry. PMID 31167792 DOI: 10.1074/Jbc.Ra119.008041 |
0.356 |
|
| 2019 |
Matossian MD, Burks HE, Elliott S, Hoang VT, Bowles AC, Sabol RA, Wahba B, Anbalagan M, Rowan B, Abazeed ME, Bunnell BA, Moroz K, Miele L, Rhodes LV, Jones SD, et al. Drug resistance profiling of a new triple negative breast cancer patient-derived xenograft model. Bmc Cancer. 19: 205. PMID 30845999 DOI: 10.1186/S12885-019-5401-2 |
0.37 |
|
| 2019 |
Hossain F, Danos D, Prakash O, Gilliland A, Ferguson TF, Simonsen N, Leonardi C, Yu Q, Wu XC, Miele L, Scribner R. Neighborhood Social Determinants of Triple Negative Breast Cancer. Frontiers in Public Health. 7: 18. PMID 30834239 DOI: 10.3389/Fpubh.2019.00018 |
0.305 |
|
| 2019 |
Sorrentino C, Hossain F, Rodriguez PC, Sierra RA, Pannuti A, Osborne BA, Minter LM, Miele L, Morello S. Adenosine A2A Receptor Stimulation Inhibits TCR-Induced Notch1 Activation in CD8+T-Cells. Frontiers in Immunology. 10: 162. PMID 30792717 DOI: 10.3389/Fimmu.2019.00162 |
0.348 |
|
| 2018 |
Hossain F, Sorrentino C, Ucar DA, Peng Y, Matossian M, Wyczechowska D, Crabtree J, Zabaleta J, Morello S, Del Valle L, Burow M, Collins-Burow B, Pannuti A, Minter LM, Golde TE, ... ... Miele L, et al. Notch Signaling Regulates Mitochondrial Metabolism and NF-κB Activity in Triple-Negative Breast Cancer Cells via IKKα-Dependent Non-canonical Pathways. Frontiers in Oncology. 8: 575. PMID 30564555 DOI: 10.3389/Fonc.2018.00575 |
0.654 |
|
| 2018 |
Mollen EWJ, Ient J, Tjan-Heijnen VCG, Boersma LJ, Miele L, Smidt ML, Vooijs MAGG. Moving Breast Cancer Therapy up a Notch. Frontiers in Oncology. 8: 518. PMID 30515368 DOI: 10.3389/fonc.2018.00518 |
0.307 |
|
| 2018 |
Crabtree JS, Miele L. Breast Cancer Stem Cells. Biomedicines. 6. PMID 30018256 DOI: 10.3390/Biomedicines6030077 |
0.474 |
|
| 2018 |
Hossain F, Majumder S, Ucar DA, Rodriguez PC, Golde TE, Minter LM, Osborne BA, Miele L. Notch Signaling in Myeloid Cells as a Regulator of Tumor Immune Responses. Frontiers in Immunology. 9: 1288. PMID 29915603 DOI: 10.3389/Fimmu.2018.01288 |
0.369 |
|
| 2018 |
Shah D, Wyatt D, Baker A, Simms P, Peiffer DS, Fernandez ML, Rakha EA, Green AR, Filipovic A, Miele L, Osipo C. Inhibition of HER2 Enriches for Jagged1-dependent Breast Cancer Stem Cells: Role for Membrane Jagged1. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29895705 DOI: 10.1158/1078-0432.Ccr-17-1952 |
0.454 |
|
| 2018 |
Chandiran K, Lawlor R, Pannuti A, Perez GG, Srinivasan J, Golde TE, Miele L, Osborne BA, Minter LM. Notch1 primes CD4 T cells for T helper type I differentiation through its early effects on miR-29. Molecular Immunology. 99: 191-198. PMID 29807327 DOI: 10.1016/J.Molimm.2018.05.002 |
0.365 |
|
| 2018 |
Baker A, Wyatt D, Bocchetta M, Li J, Filipovic A, Green A, Peiffer DS, Fuqua S, Miele L, Albain KS, Osipo C. Notch-1-PTEN-ERK1/2 signaling axis promotes HER2+ breast cancer cell proliferation and stem cell survival. Oncogene. PMID 29743588 DOI: 10.1038/S41388-018-0251-Y |
0.427 |
|
| 2018 |
Bao B, Wang Z, Ali S, Kong D, Li Y, Ahmad A, Banerjee S, Azmi AS, Miele L, Sarkar FH. Retraction notice to "Notch-1 induces Epithelial-mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells". Cancer Letters. 423: 153. PMID 29606293 DOI: 10.1016/J.Canlet.2018.03.020 |
0.336 |
|
| 2018 |
Pannuti A, Filipovic A, Hicks C, Lefkowitz E, Ptacek T, Stebbing J, Miele L. Novel putative drivers revealed by targeted exome sequencing of advanced solid tumors. Plos One. 13: e0194790. PMID 29570743 DOI: 10.1371/Journal.Pone.0194790 |
0.34 |
|
| 2018 |
Guo S, Zhang C, Bratton M, Mottamal M, Liu J, Ma P, Zheng S, Zhong Q, Yang L, Wiese TE, Wu Y, Ellis MJ, Matossian M, Burow ME, Miele L, et al. ZB716, a steroidal selective estrogen receptor degrader (SERD), is orally efficacious in blocking tumor growth in mouse xenograft models. Oncotarget. 9: 6924-6937. PMID 29467940 DOI: 10.18632/Oncotarget.24023 |
0.382 |
|
| 2018 |
Kumar D, Haldar S, Gorain M, Kumar S, Mulani FA, Yadav AS, Miele L, Thulasiram HV, Kundu GC. Epoxyazadiradione suppresses breast tumor growth through mitochondrial depolarization and caspase-dependent apoptosis by targeting PI3K/Akt pathway. Bmc Cancer. 18: 52. PMID 29310608 DOI: 10.1186/S12885-017-3876-2 |
0.431 |
|
| 2018 |
Matossian M, Burks H, Chang T, Bowles A, Sabol R, Hoang V, Bunnell B, Alfortish A, Moroz K, Zea A, Riker A, Jones S, Bilyeu ADU, Hossain F, Miller K, ... ... Miele L, et al. Abstract A01: Application of patient-derived models from understudied patient populations to discover therapeutically targetable pathways in triple-negative breast cancer systems Molecular Cancer Research. 16. DOI: 10.1158/1557-3125.Advbc17-A01 |
0.436 |
|
| 2018 |
Serrano-Gomez SJ, Sanabria-Salas MC, Garai J, Baddoo MC, Hernandez-Suarez G, Mejia JC, Garcia O, Miele L, Fejerman L, Zabaleta J. Abstract A38: Identification of triple-negative breast cancer subtypes in Colombian patients Cancer Epidemiology, Biomarkers & Prevention. 27. DOI: 10.1158/1538-7755.Disp17-A38 |
0.355 |
|
| 2018 |
Ucar-Bilyeu DA, Matossian MD, Barnes VH, Hossain FM, Gupta M, Burks HE, Wright TD, Cavanaugh J, Flaherty P, Burow ME, Miele L. Abstract 967: Targeting notch one notch above Cancer Research. 78: 967-967. DOI: 10.1158/1538-7445.Am2018-967 |
0.549 |
|
| 2018 |
Hossain F, Bilyeu ADU, Sorrentino C, Crabtree J, Pannuti A, Matossian M, Burow M, Golde T, Osborne B, Miele L. Abstract 157: Targeting cancer stem-like cells in triple negative breast cancer Cancer Research. 78: 157-157. DOI: 10.1158/1538-7445.Am2018-157 |
0.575 |
|
| 2017 |
Man J, Yu X, Huang H, Zhou W, Xiang C, Huang H, Miele L, Liu Z, Bebek G, Bao S, Yu JS. Hypoxic Induction of Vasorin Regulates Notch1 Turnover to Maintain Glioma Stem-like Cells. Cell Stem Cell. PMID 29198941 DOI: 10.1016/j.stem.2017.10.005 |
0.391 |
|
| 2017 |
Sierra RA, Trillo-Tinoco J, Mohamed E, Yu L, Achyut BR, Arbab A, Bradford JW, Osborne BA, Miele L, Rodriguez PC. Anti-Jagged immunotherapy inhibits MDSCs and overcomes tumor-induced tolerance. Cancer Research. PMID 28904063 DOI: 10.1158/0008-5472.Can-17-0357 |
0.422 |
|
| 2017 |
Serrano-Gómez SJ, Sanabria-Salas MC, Garay J, Baddoo MC, Hernández-Suarez G, Mejía JC, García O, Miele L, Fejerman L, Zabaleta J. Ancestry as a potential modifier of gene expression in breast tumors from Colombian women. Plos One. 12: e0183179. PMID 28832682 DOI: 10.1371/Journal.Pone.0183179 |
0.353 |
|
| 2017 |
Ran Y, Hossain F, Pannuti A, Lessard CB, Ladd GZ, Jung JI, Minter LM, Osborne BA, Miele L, Golde TE. γ-Secretase inhibitors in cancer clinical trials are pharmacologically and functionally distinct. Embo Molecular Medicine. PMID 28539479 DOI: 10.15252/Emmm.201607265 |
0.437 |
|
| 2017 |
Yedjou CG, Tchounwou PB, Payton M, Miele L, Fonseca DD, Lowe L, Alo RA. Assessing the Racial and Ethnic Disparities in Breast Cancer Mortality in the United States. International Journal of Environmental Research and Public Health. 14. PMID 28475137 DOI: 10.3390/Ijerph14050486 |
0.344 |
|
| 2017 |
Hicks C, Ramani R, Sartor O, Bhalla R, Miele L, Dlamini Z, Gumede N. An Integrative Genomics Approach for Associating Genome-Wide Association Studies Information With Localized and Metastatic Prostate Cancer Phenotypes. Biomarker Insights. 12: 1177271917695810. PMID 28469398 DOI: 10.1177/1177271917695810 |
0.33 |
|
| 2017 |
Serrano-Gomez SJ, Sanabria C, Baddoo MC, Cruz-Rodriguez N, Garai J, Hernandez-Suarez G, Mejia JC, Miele L, Hicks C, Fejerman L, Zabaleta J. Abstract PR05: Ancestry as a potential modifier of gene expression in luminal B tumors among Colombian women Cancer Epidemiology, Biomarkers & Prevention. 26. DOI: 10.1158/1538-7755.Disp16-Pr05 |
0.366 |
|
| 2017 |
Hossain F, Sorrentino C, Bilyeu A, Crabtree J, Pannuti A, Golde T, Osborne B, Miele L. Abstract 2904: Targeting cancer stem-like cells in triple negative breast cancer cells through non-canonical notch signaling Cancer Research. 77: 2904-2904. DOI: 10.1158/1538-7445.Am2017-2904 |
0.587 |
|
| 2016 |
Liu J, Zheng S, Akerstrom VL, Yuan C, Ma Y, Zhong Q, Zhang C, Zhang Q, Guo S, Ma P, Skripnikova EV, Bratton MR, Pannuti A, Miele L, Wiese TE, et al. Fulvestrant-3 Boronic Acid (ZB716): An Orally Bioavailable Selective Estrogen Receptor Downregulator (SERD). Journal of Medicinal Chemistry. PMID 27529700 DOI: 10.1021/Acs.Jmedchem.6B00753 |
0.359 |
|
| 2016 |
Serrano-Gomez SJ, Sanabria-Salas MC, Hernández-Suarez G, García O, Silva C, Romero A, Mejía JC, Miele L, Fejerman L, Zabaleta J. High prevalence of luminal B breast cancer intrinsic subtype in Colombian women. Carcinogenesis. PMID 27207651 DOI: 10.1093/Carcin/Bgw043 |
0.369 |
|
| 2016 |
Crabtree JS, Singleton CS, Miele L. Notch Signaling in Neuroendocrine Tumors. Frontiers in Oncology. 6: 94. PMID 27148486 DOI: 10.3389/fonc.2016.00094 |
0.314 |
|
| 2016 |
Crabtree JS, Miele L. Neuroendocrine tumors: current therapies, notch signaling, and cancer stem cells Journal of Cancer Metastasis and Treatment. 2: 279. DOI: 10.20517/2394-4722.2016.30 |
0.426 |
|
| 2016 |
Hossain F, Peng Y, Pannuti A, Backus K, Golde TE, Osborne B, Miele L. Abstract 4616: A novel non-canonical Notch-AKT- NF-κB pathways in triple negative breast cancer cells Cancer Research. 76: 4616-4616. DOI: 10.1158/1538-7445.Am2016-4616 |
0.704 |
|
| 2015 |
Verginelli F, Adesso L, Limon I, Alisi A, Gueguen M, Panera N, Giorda E, Raimondi L, Ciarapica R, Campese AF, Screpanti I, Stifani S, Kitajewski J, Miele L, Rota R, et al. Activation of an endothelial Notch1-Jagged1 circuit induces VCAM1 expression, an effect amplified by interleukin-1β. Oncotarget. PMID 26646450 DOI: 10.18632/Oncotarget.6456 |
0.364 |
|
| 2015 |
Sorrentino C, Miele L, Porta A, Pinto A, Morello S. Myeloid-derived suppressor cells contribute to A2B adenosine receptor-induced VEGF production and angiogenesis in a mouse melanoma model. Oncotarget. 6: 27478-89. PMID 26317647 DOI: 10.18632/Oncotarget.4393 |
0.354 |
|
| 2015 |
Zhang C, Zhong Q, Zhang Q, Zheng S, Miele L, Wang G. Boronic prodrug of endoxifen as an effective hormone therapy for breast cancer. Breast Cancer Research and Treatment. 152: 283-91. PMID 26071758 DOI: 10.1007/S10549-015-3461-9 |
0.356 |
|
| 2015 |
Yun J, Espinoza I, Pannuti A, Romero D, Martinez L, Caskey M, Stanculescu A, Bocchetta M, Rizzo P, Band V, Band H, Kim HM, Park SK, Kang KW, Avantaggiati ML, ... ... Miele L, et al. p53 Modulates Notch Signaling in MCF-7 Breast Cancer Cells by Associating with the Notch Transcriptional Complex via MAML1. Journal of Cellular Physiology. PMID 26033683 DOI: 10.1002/Jcp.25052 |
0.366 |
|
| 2015 |
Takebe N, Miele L, Harris PJ, Jeong W, Bando H, Kahn M, Yang SX, Ivy SP. Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update. Nature Reviews. Clinical Oncology. PMID 25850553 DOI: 10.1038/nrclinonc.2015.61 |
0.367 |
|
| 2015 |
Zhang S, Chung WC, Wu G, Egan SE, Miele L, Xu K. Manic fringe promotes a claudin-low breast cancer phenotype through notch-mediated PIK3CG induction. Cancer Research. 75: 1936-43. PMID 25808869 DOI: 10.1158/0008-5472.CAN-14-3303 |
0.415 |
|
| 2015 |
Ramakrishnan G, Davaakhuu G, Chung WC, Zhu H, Rana A, Filipovic A, Green AR, Atfi A, Pannuti A, Miele L, Tzivion G. AKT and 14-3-3 regulate Notch4 nuclear localization. Scientific Reports. 5: 8782. PMID 25740432 DOI: 10.1038/Srep08782 |
0.388 |
|
| 2015 |
Nguyen D, Rubinstein L, Takebe N, Miele L, Tomaszewski JE, Ivy P, Doroshow JH, Yang SX. Notch1 phenotype and clinical stage progression in non-small cell lung cancer. Journal of Hematology & Oncology. 8: 9. PMID 25653136 DOI: 10.1186/s13045-014-0104-2 |
0.33 |
|
| 2015 |
Su RW, Strug MR, Joshi NR, Jeong JW, Miele L, Lessey BA, Young SL, Fazleabas AT. Decreased Notch pathway signaling in the endometrium of women with endometriosis impairs decidualization. The Journal of Clinical Endocrinology and Metabolism. 100: E433-42. PMID 25546156 DOI: 10.1210/Jc.2014-3720 |
0.323 |
|
| 2015 |
Filipovic A, Miele L, Stebbing J. Whole exome next-generation sequencing of triple-negative breast cancers and rare tumours to reveal novel molecular pathways and therapeutic targets for personalized therapy. Journal of Clinical Oncology. 33. DOI: 10.1200/Jco.2015.33.15_Suppl.E12534 |
0.345 |
|
| 2015 |
White V, Miele L, Estrada J, Cvitanovic J, Zea A. ARG2 and NOS2 as predictive biomarkers in renal cell carcinoma Journal For Immunotherapy of Cancer. 3: P110. DOI: 10.1186/2051-1426-3-S2-P110 |
0.43 |
|
| 2015 |
Fortini F, Caliceti C, Pannella M, Aquila G, Morelli M, Pannuti A, Miele L, Rizzo P, Ferrari R. Estrogen receptor β is involved in 17β-estradiol-mediated Notch1 activation and angiogenesis enhancement in human endothelial cells Vascular Pharmacology. 75: 53. DOI: 10.1016/J.Vph.2015.11.036 |
0.315 |
|
| 2014 |
Chinchar E, Makey KL, Gibson J, Chen F, Cole SA, Megason GC, Vijayakumar S, Miele L, Gu JW. Sunitinib significantly suppresses the proliferation, migration, apoptosis resistance, tumor angiogenesis and growth of triple-negative breast cancers but increases breast cancer stem cells. Vascular Cell. 6: 12. PMID 24914410 DOI: 10.1186/2045-824X-6-12 |
0.375 |
|
| 2014 |
Shin HM, Tilahun ME, Cho OH, Chandiran K, Kuksin CA, Keerthivasan S, Fauq AH, Golde TE, Miele L, Thome M, Osborne BA, Minter LM. NOTCH1 Can Initiate NF-κB Activation via Cytosolic Interactions with Components of the T Cell Signalosome. Frontiers in Immunology. 5: 249. PMID 24904593 DOI: 10.3389/Fimmu.2014.00249 |
0.368 |
|
| 2014 |
De Salvo M, Raimondi L, Vella S, Adesso L, Ciarapica R, Verginelli F, Pannuti A, Citti A, Boldrini R, Milano GM, Cacchione A, Ferrari A, Collini P, Rosolen A, Bisogno G, ... ... Miele L, et al. Hyper-activation of Notch3 amplifies the proliferative potential of rhabdomyosarcoma cells. Plos One. 9: e96238. PMID 24797362 DOI: 10.1371/Journal.Pone.0096238 |
0.436 |
|
| 2014 |
Dongre A, Surampudi L, Lawlor RG, Fauq AH, Miele L, Golde TE, Minter LM, Osborne BA. Non-Canonical Notch Signaling Drives Activation and Differentiation of Peripheral CD4(+) T Cells. Frontiers in Immunology. 5: 54. PMID 24611064 DOI: 10.3389/Fimmu.2014.00054 |
0.372 |
|
| 2014 |
Zhang S, Chung WC, Miele L, Xu K. Targeting Met and Notch in the Lfng-deficient, Met-amplified triple-negative breast cancer. Cancer Biology & Therapy. 15: 633-42. PMID 24556651 DOI: 10.4161/cbt.28180 |
0.45 |
|
| 2014 |
Bell D, Hanna EY, Miele L, Roberts D, Weber RS, El-Naggar AK. Expression and significance of notch signaling pathway in salivary adenoid cystic carcinoma. Annals of Diagnostic Pathology. 18: 10-3. PMID 24238845 DOI: 10.1016/j.anndiagpath.2013.10.001 |
0.394 |
|
| 2014 |
Ciarapica R, De Salvo M, Carcarino E, Bracaglia G, Adesso L, Leoncini PP, Dall'Agnese A, Walters ZS, Verginelli F, De Sio L, Boldrini R, Inserra A, Bisogno G, Rosolen A, Alaggio R, ... ... Miele L, et al. The Polycomb group (PcG) protein EZH2 supports the survival of PAX3-FOXO1 alveolar rhabdomyosarcoma by repressing FBXO32 (Atrogin1/MAFbx). Oncogene. 33: 4173-84. PMID 24213577 DOI: 10.1038/Onc.2013.471 |
0.422 |
|
| 2014 |
Filipovic A, Zhu H, Pannuti A, Espinoza I, Green A, Miele L. Correlation of Notch1 expression with clinical characteristics, signaling biomarkers, and survival in breast cancer patients. Journal of Clinical Oncology. 32: 1129-1129. DOI: 10.1200/jco.2014.32.15_suppl.1129 |
0.304 |
|
| 2014 |
Papa FT, Espinoza I, Darack-Gutyon N, Giordano A, Luca AD, Gomez CR, Miele L. Abstract 1311: Notch1 inhibits retinoblastoma (RB) via direct interaction with RB pocket domain Cancer Research. 74: 1311-1311. DOI: 10.1158/1538-7445.Am2014-1311 |
0.439 |
|
| 2014 |
Gao J, Sarkar FH, Miele L, Wang Z. The Role of Notch Signaling Pathway in the Progression of Pancreatic Cancer Molecular Diagnostics and Treatment of Pancreatic Cancer. 75-89. DOI: 10.1016/B978-0-12-408103-1.00004-2 |
0.395 |
|
| 2013 |
Li Y, Ma J, Qian X, Wu Q, Xia J, Miele L, Sarkar FH, Wang Z. Regulation of EMT by Notch signaling pathway in tumor progression. Current Cancer Drug Targets. 13: 957-62. PMID 24168187 DOI: 10.2174/15680096113136660101 |
0.383 |
|
| 2013 |
Espinoza I, Pochampally R, Xing F, Watabe K, Miele L. Notch signaling: targeting cancer stem cells and epithelial-to-mesenchymal transition. Oncotargets and Therapy. 6: 1249-59. PMID 24043949 DOI: 10.2147/Ott.S36162 |
0.361 |
|
| 2013 |
Ma J, Xia J, Miele L, Sarkar FH, Wang Z. Notch Signaling Pathway in Pancreatic Cancer Progression. Pancreatic Disorders & Therapy. 3. PMID 24027656 DOI: 10.4172/2165-7092.1000114 |
0.33 |
|
| 2013 |
Cao Z, Bao M, Miele L, Sarkar FH, Wang Z, Zhou Q. Tumour vasculogenic mimicry is associated with poor prognosis of human cancer patients: a systemic review and meta-analysis. European Journal of Cancer (Oxford, England : 1990). 49: 3914-23. PMID 23992642 DOI: 10.1016/J.Ejca.2013.07.148 |
0.331 |
|
| 2013 |
Espinoza I, Miele L. Deadly crosstalk: Notch signaling at the intersection of EMT and cancer stem cells. Cancer Letters. 341: 41-5. PMID 23973264 DOI: 10.1016/j.canlet.2013.08.027 |
0.393 |
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| 2013 |
Caliceti C, Aquila G, Pannella M, Morelli MB, Fortini C, Pinton P, Bonora M, Hrelia S, Pannuti A, Miele L, Rizzo P, Ferrari R. 17β-estradiol enhances signalling mediated by VEGF-A-delta-like ligand 4-notch1 axis in human endothelial cells. Plos One. 8: e71440. PMID 23967210 DOI: 10.1371/journal.pone.0071440 |
0.305 |
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| 2013 |
Cao Z, Shang B, Zhang G, Miele L, Sarkar FH, Wang Z, Zhou Q. Tumor cell-mediated neovascularization and lymphangiogenesis contrive tumor progression and cancer metastasis. Biochimica Et Biophysica Acta. 1836: 273-86. PMID 23933263 DOI: 10.1016/J.Bbcan.2013.08.001 |
0.389 |
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| 2013 |
Ma J, Zhang Q, Chen S, Fang B, Yang Q, Chen C, Miele L, Sarkar FH, Xia J, Wang Z. Mitochondrial dysfunction promotes breast cancer cell migration and invasion through HIF1α accumulation via increased production of reactive oxygen species. Plos One. 8: e69485. PMID 23922721 DOI: 10.1371/Journal.Pone.0069485 |
0.373 |
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| 2013 |
Yun J, Pannuti A, Espinoza I, Zhu H, Hicks C, Zhu X, Caskey M, Rizzo P, D'Souza G, Backus K, Denning MF, Coon J, Sun M, Bresnick EH, Osipo C, ... ... Miele L, et al. Crosstalk between PKCα and Notch-4 in endocrine-resistant breast cancer cells. Oncogenesis. 2: e60. PMID 23917222 DOI: 10.1038/oncsis.2013.26 |
0.424 |
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| 2013 |
Mo YY, Tang H, Miele L. Notch-associated microRNAs in cancer. Current Drug Targets. 14: 1157-66. PMID 23834150 DOI: 10.2174/13894501113149990188 |
0.384 |
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| 2013 |
Ma J, Cheng L, Liu H, Zhang J, Shi Y, Zeng F, Miele L, Sarkar FH, Xia J, Wang Z. Genistein down-regulates miR-223 expression in pancreatic cancer cells Current Drug Targets. 14: 1150-1156. PMID 23834147 DOI: 10.2174/13894501113149990187 |
0.386 |
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| 2013 |
Wang R, Ma J, Wu Q, Xia J, Miele L, Sarkar FH, Wang Z. Functional role of miR-34 family in human cancer Current Drug Targets. 14: 1185-1191. PMID 23834144 DOI: 10.2174/13894501113149990191 |
0.305 |
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| 2013 |
Roderick JE, Gonzalez-Perez G, Kuksin CA, Dongre A, Roberts ER, Srinivasan J, Andrzejewski C, Fauq AH, Golde TE, Miele L, Minter LM. Therapeutic targeting of NOTCH signaling ameliorates immune-mediated bone marrow failure of aplastic anemia. The Journal of Experimental Medicine. 210: 1311-29. PMID 23733784 DOI: 10.1084/Jem.20112615 |
0.341 |
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| 2013 |
Gopisetty A, Bhattacharya P, Haddad C, Bruno JC, Vasu C, Miele L, Prabhakar BS. OX40L/Jagged1 cosignaling by GM-CSF-induced bone marrow-derived dendritic cells is required for the expansion of functional regulatory T cells. Journal of Immunology (Baltimore, Md. : 1950). 190: 5516-25. PMID 23630352 DOI: 10.4049/Jimmunol.1202298 |
0.363 |
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| 2013 |
Zhu H, Bhaijee F, Ishaq N, Pepper DJ, Backus K, Brown AS, Zhou X, Miele L. Correlation of Notch1, pAKT and nuclear NF-κB expression in triple negative breast cancer. American Journal of Cancer Research. 3: 230-9. PMID 23593544 |
0.379 |
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| 2013 |
Zhang G, Yang P, Guo P, Miele L, Sarkar FH, Wang Z, Zhou Q. Unraveling the mystery of cancer metabolism in the genesis of tumor-initiating cells and development of cancer. Biochimica Et Biophysica Acta. 1836: 49-59. PMID 23523716 DOI: 10.1016/J.Bbcan.2013.03.001 |
0.343 |
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| 2013 |
Espinoza I, Miele L. Notch inhibitors for cancer treatment. Pharmacology & Therapeutics. 139: 95-110. PMID 23458608 DOI: 10.1016/J.Pharmthera.2013.02.003 |
0.534 |
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| 2013 |
Wu Q, Hou X, Xia J, Qian X, Miele L, Sarkar FH, Wang Z. Emerging roles of PDGF-D in EMT progression during tumorigenesis Cancer Treatment Reviews. 39: 640-646. PMID 23261166 DOI: 10.1016/J.Ctrv.2012.11.006 |
0.365 |
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| 2013 |
Tan Y, Wu Q, Xia J, Miele L, Sarkar FH, Wang Z. Systems biology approaches in identifying the targets of natural compounds for cancer therapy Current Drug Discovery Technologies. 10: 139-146. PMID 23237676 DOI: 10.2174/1570163811310020006 |
0.329 |
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| 2013 |
Espinoza I, Miele L. Development of notch pathway inhibitors for cancer therapy Breast Cancer Metastasis and Drug Resistance: Progress and Prospects. 2147483647: 291-327. DOI: 10.1007/978-1-4614-5647-6_17 |
0.409 |
|
| 2012 |
Wu Q, Miele L, Sarkar FH, Wang Z. The Role of EMT in Pancreatic Cancer Progression. Pancreatic Disorders & Therapy. 2. PMID 23145368 DOI: 10.4172/2165-7092.1000E121 |
0.392 |
|
| 2012 |
Xia J, Duan Q, Ahmad A, Bao B, Banerjee S, Shi Y, Ma J, Geng J, Chen Z, Rahman KM, Miele L, Sarkar FH, Wang Z. Genistein inhibits cell growth and induces apoptosis through up-regulation of miR-34a in pancreatic cancer cells. Current Drug Targets. 13: 1750-6. PMID 23140286 DOI: 10.2174/138945012804545597 |
0.401 |
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| 2012 |
Xia J, Li Y, Yang Q, Mei C, Chen Z, Bao B, Ahmad A, Miele L, Sarkar FH, Wang Z. Arsenic trioxide inhibits cell growth and induces apoptosis through inactivation of notch signaling pathway in breast cancer. International Journal of Molecular Sciences. 13: 9627-41. PMID 22949821 DOI: 10.3390/Ijms13089627 |
0.551 |
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| 2012 |
Xia J, Chen C, Chen Z, Miele L, Sarkar FH, Wang Z. Targeting pancreatic cancer stem cells for cancer therapy. Biochimica Et Biophysica Acta. 1826: 385-99. PMID 22728049 DOI: 10.1016/J.Bbcan.2012.06.002 |
0.429 |
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| 2012 |
Pallavi SK, Ho DM, Hicks C, Miele L, Artavanis-Tsakonas S. Notch and Mef2 synergize to promote proliferation and metastasis through JNK signal activation in Drosophila. The Embo Journal. 31: 2895-907. PMID 22580825 DOI: 10.1038/Emboj.2012.129 |
0.348 |
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| 2012 |
Afshar Y, Miele L, Fazleabas AT. Notch1 is regulated by chorionic gonadotropin and progesterone in endometrial stromal cells and modulates decidualization in primates. Endocrinology. 153: 2884-96. PMID 22535768 DOI: 10.1210/En.2011-2122 |
0.424 |
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| 2012 |
Gu JW, Rizzo P, Pannuti A, Golde T, Osborne B, Miele L. Notch signals in the endothelium and cancer "stem-like" cells: opportunities for cancer therapy. Vascular Cell. 4: 7. PMID 22487493 DOI: 10.1186/2045-824X-4-7 |
0.458 |
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| 2012 |
Raimondi L, Ciarapica R, De Salvo M, Verginelli F, Gueguen M, Martini C, De Sio L, Cortese G, Locatelli M, Dang TP, Carlesso N, Miele L, Stifani S, Limon I, Locatelli F, et al. Inhibition of Notch3 signalling induces rhabdomyosarcoma cell differentiation promoting p38 phosphorylation and p21(Cip1) expression and hampers tumour cell growth in vitro and in vivo. Cell Death and Differentiation. 19: 871-81. PMID 22117196 DOI: 10.1038/Cdd.2011.171 |
0.492 |
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| 2012 |
Afshar Y, Jeong JW, Roqueiro D, DeMayo F, Lydon J, Radtke F, Radnor R, Miele L, Fazleabas A. Notch1 mediates uterine stromal differentiation and is critical for complete decidualization in the mouse. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 282-94. PMID 21990372 DOI: 10.1096/Fj.11-184663 |
0.508 |
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| 2012 |
Espinoza I, Caskey M, Baker R, Miele L. Abstract P6-04-22: Regulation of Notch localization by endocrine therapy in Estrogen Receptor positive breast cancer cells: Clinical implications for endocrine resistance Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-P6-04-22 |
0.515 |
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| 2011 |
Cho S, Lu M, He X, Ee PL, Bhat U, Schneider E, Miele L, Beck WT. Notch1 regulates the expression of the multidrug resistance gene ABCC1/MRP1 in cultured cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 20778-83. PMID 22143792 DOI: 10.1073/Pnas.1019452108 |
0.373 |
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| 2011 |
Pandya K, Meeke K, Clementz AG, Rogowski A, Roberts J, Miele L, Albain KS, Osipo C. Targeting both Notch and ErbB-2 signalling pathways is required for prevention of ErbB-2-positive breast tumour recurrence. British Journal of Cancer. 105: 796-806. PMID 21847123 DOI: 10.1038/Bjc.2011.321 |
0.404 |
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| 2011 |
Keerthivasan S, Suleiman R, Lawlor R, Roderick J, Bates T, Minter L, Anguita J, Juncadella I, Nickoloff BJ, Le Poole IC, Miele L, Osborne BA. Notch signaling regulates mouse and human Th17 differentiation. Journal of Immunology (Baltimore, Md. : 1950). 187: 692-701. PMID 21685328 DOI: 10.4049/Jimmunol.1003658 |
0.303 |
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| 2011 |
Clementz AG, Rogowski A, Pandya K, Miele L, Osipo C. NOTCH-1 and NOTCH-4 are novel gene targets of PEA3 in breast cancer: novel therapeutic implications. Breast Cancer Research : Bcr. 13: R63. PMID 21679465 DOI: 10.1186/Bcr2900 |
0.439 |
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| 2011 |
Wang Z, Banerjee S, Ahmad A, Li Y, Azmi AS, Gunn JR, Kong D, Bao B, Ali S, Gao J, Mohammad RM, Miele L, Korc M, Sarkar FH. Activated K-ras and INK4a/Arf deficiency cooperate during the development of pancreatic cancer by activation of Notch and NF-κB signaling pathways. Plos One. 6: e20537. PMID 21673986 DOI: 10.1371/Journal.Pone.0020537 |
0.315 |
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| 2011 |
Hicks C, Pannuti A, Miele L. Associating GWAS Information with the Notch Signaling Pathway Using Transcription Profiling. Cancer Informatics. 10: 93-108. PMID 21584266 DOI: 10.4137/CIN.S6072 |
0.331 |
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| 2011 |
Wang Z, Ahmad A, Li Y, Azmi AS, Miele L, Sarkar FH. Targeting notch to eradicate pancreatic cancer stem cells for cancer therapy. Anticancer Research. 31: 1105-13. PMID 21508353 |
0.359 |
|
| 2011 |
Bao B, Wang Z, Ali S, Kong D, Banerjee S, Ahmad A, Li Y, Azmi AS, Miele L, Sarkar FH. Over-expression of FoxM1 leads to epithelial-mesenchymal transition and cancer stem cell phenotype in pancreatic cancer cells. Journal of Cellular Biochemistry. 112: 2296-306. PMID 21503965 DOI: 10.1002/Jcb.23150 |
0.438 |
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| 2011 |
Bao B, Wang Z, Ali S, Kong D, Li Y, Ahmad A, Banerjee S, Azmi AS, Miele L, Sarkar FH. Notch-1 induces epithelial-mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells. Cancer Letters. 307: 26-36. PMID 21463919 DOI: 10.1016/J.Canlet.2011.03.012 |
0.447 |
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| 2011 |
Bell D, Miele L. A magnifying glass on glioblastoma stem cell signaling pathways. Cancer Biology & Therapy. 11: 765-8. PMID 21386658 DOI: 10.4161/Cbt.11.8.15277 |
0.367 |
|
| 2011 |
Liao S, Xia J, Chen Z, Zhang S, Ahmad A, Miele L, Sarkar FH, Wang Z. Inhibitory effect of curcumin on oral carcinoma CAL-27 cells via suppression of Notch-1 and NF-κB signaling pathways. Journal of Cellular Biochemistry. 112: 1055-65. PMID 21308734 DOI: 10.1002/Jcb.23019 |
0.535 |
|
| 2011 |
Wang Z, Li Y, Ahmad A, Banerjee S, Azmi AS, Kong D, Wojewoda C, Miele L, Sarkar FH. Down-regulation of Notch-1 is associated with Akt and FoxM1 in inducing cell growth inhibition and apoptosis in prostate cancer cells. Journal of Cellular Biochemistry. 112: 78-88. PMID 20658545 DOI: 10.1002/Jcb.22770 |
0.53 |
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| 2011 |
Yao K, Rizzo P, Rajan P, Albain K, Rychlik K, Shah S, Miele L. Notch-1 and notch-4 receptors as prognostic markers in breast cancer. International Journal of Surgical Pathology. 19: 607-13. PMID 20444726 DOI: 10.1177/1066896910362080 |
0.387 |
|
| 2010 |
Grudzien P, Lo S, Albain KS, Robinson P, Rajan P, Strack PR, Golde TE, Miele L, Foreman KE. Inhibition of Notch signaling reduces the stem-like population of breast cancer cells and prevents mammosphere formation. Anticancer Research. 30: 3853-67. PMID 21036696 |
0.383 |
|
| 2010 |
Young E, Miele L, Tucker KB, Huang M, Wells J, Gu JW. SU11248, a selective tyrosine kinases inhibitor suppresses breast tumor angiogenesis and growth via targeting both tumor vasculature and breast cancer cells. Cancer Biology & Therapy. 10: 703-11. PMID 20686367 DOI: 10.4161/cbt.10.7.12904 |
0.323 |
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| 2010 |
Pannuti A, Foreman K, Rizzo P, Osipo C, Golde T, Osborne B, Miele L. Targeting Notch to target cancer stem cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 3141-52. PMID 20530696 DOI: 10.1158/1078-0432.Ccr-09-2823 |
0.369 |
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| 2010 |
Dumortier A, Durham AD, Di Piazza M, Vauclair S, Koch U, Ferrand G, Ferrero I, Demehri S, Song LL, Farr AG, Leonard WJ, Kopan R, Miele L, Hohl D, Finke D, et al. Atopic dermatitis-like disease and associated lethal myeloproliferative disorder arise from loss of Notch signaling in the murine skin. Plos One. 5: e9258. PMID 20174635 DOI: 10.1371/Journal.Pone.0009258 |
0.359 |
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| 2010 |
Eliasz S, Liang S, Chen Y, De Marco MA, Machek O, Skucha S, Miele L, Bocchetta M. Notch-1 stimulates survival of lung adenocarcinoma cells during hypoxia by activating the IGF-1R pathway. Oncogene. 29: 2488-98. PMID 20154720 DOI: 10.1038/Onc.2010.7 |
0.347 |
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| 2010 |
Hao L, Rizzo P, Osipo C, Pannuti A, Wyatt D, Cheung LW, Sonenshein G, Osborne BA, Miele L. Notch-1 activates estrogen receptor-alpha-dependent transcription via IKKalpha in breast cancer cells. Oncogene. 29: 201-13. PMID 19838210 DOI: 10.1038/Onc.2009.323 |
0.607 |
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| 2010 |
Mehta K, Meeke K, Patel P, Miele L, Osipo C. Abstract 614: ErbB-2 Suppresses Notch-1 Signaling by Regulating Jagged-1 Localization in ErbB-2 positive breast cancer Cancer Research. 70: 614-614. DOI: 10.1158/1538-7445.Am10-614 |
0.523 |
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| 2010 |
Clementz AG, Rizzo P, Miele L, Osipo C. Abstract 3918: PEA3 is a novel transcriptional activator of Notch-1 and Notch-4 in breast cancer: Opportunity for a new combination strategy Cancer Research. 70: 3918-3918. DOI: 10.1158/1538-7445.Am10-3918 |
0.489 |
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| 2009 |
Rizzo P, Osipo C, Pannuti A, Golde T, Osborne B, Miele L. Targeting Notch signaling cross-talk with estrogen receptor and ErbB-2 in breast cancer. Advances in Enzyme Regulation. 49: 134-41. PMID 19344631 DOI: 10.1016/J.Advenzreg.2009.01.008 |
0.425 |
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| 2009 |
Cho OH, Shin HM, Miele L, Golde TE, Fauq A, Minter LM, Osborne BA. Notch regulates cytolytic effector function in CD8+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 182: 3380-9. PMID 19265115 DOI: 10.4049/Jimmunol.0802598 |
0.403 |
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| 2009 |
Foreman K, Grudzien P, Lo S, Robinson P, Albain K, Strack P, Miele L. Blockade of Notch Signaling with Gamma-Secretase Inhibitors Induces Apoptosis in the Stem-Like Population of Breast Cancer Cells. Cancer Research. 69: 1154-1154. DOI: 10.1158/0008-5472.Sabcs-09-1154 |
0.542 |
|
| 2009 |
Afshar Y, Miele L, Jeong J, DeMayo FJ, Fazleabas AT. Notch1 Is Essential for Successful Decidualization and Is Regulated by Ovarian and Embryonic Hormones. Biology of Reproduction. 81: 30-30. DOI: 10.1093/Biolreprod/81.S1.30 |
0.311 |
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| 2008 |
Chi A, Yun J, Osipo C, Rizzo P, Wyatt D, Sabou A, Albuquerque K, Miele L. The additive effects of gamma secretase inhibitor and ionizing radiation in MDA-MD-231 breast cancer cell line. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 14594. PMID 27950086 DOI: 10.1200/Jco.2008.26.15_Suppl.14594 |
0.402 |
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| 2008 |
Graziani I, Eliasz S, De Marco MA, Chen Y, Pass HI, De May RM, Strack PR, Miele L, Bocchetta M. Opposite effects of Notch-1 and Notch-2 on mesothelioma cell survival under hypoxia are exerted through the Akt pathway. Cancer Research. 68: 9678-85. PMID 19047145 DOI: 10.1158/0008-5472.Can-08-0969 |
0.433 |
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| 2008 |
Rizzo P, Osipo C, Foreman K, Golde T, Osborne B, Miele L. Rational targeting of Notch signaling in cancer. Oncogene. 27: 5124-31. PMID 18758481 DOI: 10.1038/Onc.2008.226 |
0.515 |
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| 2008 |
Miele L. Rational targeting of Notch signaling in breast cancer. Expert Review of Anticancer Therapy. 8: 1197-202. PMID 18699758 DOI: 10.1586/14737140.8.8.1197 |
0.484 |
|
| 2008 |
Rizzo P, Miao H, D'Souza G, Osipo C, Song LL, Yun J, Zhao H, Mascarenhas J, Wyatt D, Antico G, Hao L, Yao K, Rajan P, Hicks C, Siziopikou K, ... ... Miele L, et al. Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches. Cancer Research. 68: 5226-35. PMID 18593923 DOI: 10.1158/0008-5472.Can-07-5744 |
0.759 |
|
| 2008 |
Song LL, Peng Y, Yun J, Rizzo P, Chaturvedi V, Weijzen S, Kast WM, Stone PJ, Santos L, Loredo A, Lendahl U, Sonenshein G, Osborne B, Qin JZ, Pannuti A, ... ... Miele L, et al. Notch-1 associates with IKKalpha and regulates IKK activity in cervical cancer cells. Oncogene. 27: 5833-44. PMID 18560356 DOI: 10.1038/Onc.2008.190 |
0.672 |
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| 2008 |
Samon JB, Champhekar A, Minter LM, Telfer JC, Miele L, Fauq A, Das P, Golde TE, Osborne BA. Notch1 and TGFbeta1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells. Blood. 112: 1813-21. PMID 18550850 DOI: 10.1182/Blood-2008-03-144980 |
0.454 |
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| 2008 |
Osipo C, Patel P, Rizzo P, Clementz AG, Hao L, Golde TE, Miele L. ErbB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to a gamma-secretase inhibitor. Oncogene. 27: 5019-32. PMID 18469855 DOI: 10.1038/Onc.2008.149 |
0.607 |
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| 2008 |
Osipo C, Golde TE, Osborne BA, Miele LA. Off the beaten pathway: the complex cross talk between Notch and NF-kappaB. Laboratory Investigation; a Journal of Technical Methods and Pathology. 88: 11-7. PMID 18059366 DOI: 10.1038/Labinvest.3700700 |
0.311 |
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| 2007 |
Chigurupati S, Arumugam TV, Son TG, Lathia JD, Jameel S, Mughal MR, Tang SC, Jo DG, Camandola S, Giunta M, Rakova I, McDonnell N, Miele L, Mattson MP, Poosala S. Involvement of notch signaling in wound healing. Plos One. 2: e1167. PMID 18000539 DOI: 10.1371/Journal.Pone.0001167 |
0.387 |
|
| 2007 |
Chen Y, De Marco MA, Graziani I, Gazdar AF, Strack PR, Miele L, Bocchetta M. Oxygen concentration determines the biological effects of NOTCH-1 signaling in adenocarcinoma of the lung. Cancer Research. 67: 7954-9. PMID 17804701 DOI: 10.1158/0008-5472.Can-07-1229 |
0.375 |
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| 2007 |
Afshar Y, Stanculescu A, Miele L, Fazleabas AT. The role of chorionic gonadotropin and Notch1 in implantation. Journal of Assisted Reproduction and Genetics. 24: 296-302. PMID 17616802 DOI: 10.1007/S10815-007-9149-2 |
0.311 |
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| 2007 |
Curry CL, Reed LL, Broude E, Golde TE, Miele L, Foreman KE. Notch inhibition in Kaposi's sarcoma tumor cells leads to mitotic catastrophe through nuclear factor-kappaB signaling. Molecular Cancer Therapeutics. 6: 1983-92. PMID 17604336 DOI: 10.1158/1535-7163.Mct-07-0093 |
0.5 |
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| 2007 |
Song LL, Miele L. Cancer stem cells--an old idea that's new again: implications for the diagnosis and treatment of breast cancer. Expert Opinion On Biological Therapy. 7: 431-8. PMID 17373895 DOI: 10.1517/14712598.7.4.431 |
0.418 |
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| 2007 |
Vilimas T, Mascarenhas J, Palomero T, Mandal M, Buonamici S, Meng F, Thompson B, Spaulding C, Macaroun S, Alegre ML, Kee BL, Ferrando A, Miele L, Aifantis I. Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia. Nature Medicine. 13: 70-7. PMID 17173050 DOI: 10.1038/Nm1524 |
0.749 |
|
| 2006 |
Miele L, Golde T, Osborne B. Notch signaling in cancer. Current Molecular Medicine. 6: 905-18. PMID 17168741 DOI: 10.2174/156652406779010830 |
0.474 |
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| 2006 |
Miele L, Miao H, Nickoloff BJ. NOTCH signaling as a novel cancer therapeutic target. Current Cancer Drug Targets. 6: 313-23. PMID 16848722 DOI: 10.2174/156800906777441771 |
0.4 |
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| 2006 |
Curry CL, Reed LL, Nickoloff BJ, Miele L, Foreman KE. Notch-independent regulation of Hes-1 expression by c-Jun N-terminal kinase signaling in human endothelial cells. Laboratory Investigation; a Journal of Technical Methods and Pathology. 86: 842-52. PMID 16732296 DOI: 10.1038/Labinvest.3700442 |
0.525 |
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| 2005 |
Nickoloff BJ, Hendrix MJ, Pollock PM, Trent JM, Miele L, Qin JZ. Notch and NOXA-related pathways in melanoma cells. The Journal of Investigative Dermatology. Symposium Proceedings / the Society For Investigative Dermatology, Inc. [and] European Society For Dermatological Research. 10: 95-104. PMID 16363061 DOI: 10.1111/J.1087-0024.2005.200404.X |
0.435 |
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| 2005 |
Qin JZ, Ziffra J, Stennett L, Bodner B, Bonish BK, Chaturvedi V, Bennett F, Pollock PM, Trent JM, Hendrix MJ, Rizzo P, Miele L, Nickoloff BJ. Proteasome inhibitors trigger NOXA-mediated apoptosis in melanoma and myeloma cells. Cancer Research. 65: 6282-93. PMID 16024630 DOI: 10.1158/0008-5472.Can-05-0676 |
0.463 |
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| 2005 |
Sarmento LM, Huang H, Limon A, Gordon W, Fernandes J, Tavares MJ, Miele L, Cardoso AA, Classon M, Carlesso N. Notch1 modulates timing of G1-S progression by inducing SKP2 transcription and p27 Kip1 degradation. The Journal of Experimental Medicine. 202: 157-68. PMID 15998794 DOI: 10.1084/jem.20050559 |
0.366 |
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| 2005 |
Curry CL, Reed LL, Golde TE, Miele L, Nickoloff BJ, Foreman KE. Gamma secretase inhibitor blocks Notch activation and induces apoptosis in Kaposi's sarcoma tumor cells. Oncogene. 24: 6333-44. PMID 15940249 DOI: 10.1038/Sj.Onc.1208783 |
0.404 |
|
| 2005 |
Song L, Zlobin A, Ghoshal P, Zhang Q, Houde C, Weijzen S, Jiang Q, Nacheva E, Yagan D, Davis E, Galiegue-Zouitina S, Catovsky D, Grogan T, Fisher RI, Miele L, et al. Alteration of SMRT tumor suppressor function in transformed non-Hodgkin lymphomas. Cancer Research. 65: 4554-61. PMID 15930272 DOI: 10.1158/0008-5472.Can-04-4108 |
0.326 |
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| 2005 |
Song LL, Miele L. Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells Women's Oncology Review. 5: 9-11. DOI: 10.3109/14733400500089633 |
0.412 |
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| 2004 |
Qin JZ, Stennett L, Bacon P, Bodner B, Hendrix MJ, Seftor RE, Seftor EA, Margaryan NV, Pollock PM, Curtis A, Trent JM, Bennett F, Miele L, Nickoloff BJ. p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas. Molecular Cancer Therapeutics. 3: 895-902. PMID 15299072 |
0.33 |
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| 2004 |
Baldi A, De Falco M, De Luca L, Cottone G, Paggi MG, Nickoloff BJ, Miele L, De Luca A. Characterization of tissue specific expression of Notch-1 in human tissues. Biology of the Cell / Under the Auspices of the European Cell Biology Organization. 96: 303-11. PMID 15145534 DOI: 10.1016/J.Biolcel.2004.01.005 |
0.332 |
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| 2004 |
Jang MS, Miao H, Carlesso N, Shelly L, Zlobin A, Darack N, Qin JZ, Nickoloff BJ, Miele L. Notch-1 regulates cell death independently of differentiation in murine erythroleukemia cells through multiple apoptosis and cell cycle pathways. Journal of Cellular Physiology. 199: 418-33. PMID 15095289 DOI: 10.1002/Jcp.10467 |
0.679 |
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| 2003 |
Nickoloff BJ, Osborne BA, Miele L. Notch signaling as a therapeutic target in cancer: a new approach to the development of cell fate modifying agents. Oncogene. 22: 6598-608. PMID 14528285 DOI: 10.1038/Sj.Onc.1206758 |
0.369 |
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| 2003 |
Palaga T, Miele L, Golde TE, Osborne BA. TCR-mediated Notch signaling regulates proliferation and IFN-gamma production in peripheral T cells. Journal of Immunology (Baltimore, Md. : 1950). 171: 3019-24. PMID 12960327 DOI: 10.4049/Jimmunol.171.6.3019 |
0.344 |
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| 2003 |
Bocchetta M, Miele L, Pass HI, Carbone M. Notch-1 induction, a novel activity of SV40 required for growth of SV40-transformed human mesothelial cells. Oncogene. 22: 81-9. PMID 12527910 DOI: 10.1038/Sj.Onc.1206097 |
0.305 |
|
| 2003 |
Miele L. Apoptosis and antiapoptosis in multimodality cancer treatment Cancer Immunology, Immunotherapy. 52. |
0.388 |
|
| 2002 |
Weijzen S, Velders MP, Elmishad AG, Bacon PE, Panella JR, Nickoloff BJ, Miele L, Kast WM. The Notch ligand Jagged-1 is able to induce maturation of monocyte-derived human dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 169: 4273-8. PMID 12370358 DOI: 10.4049/Jimmunol.169.8.4273 |
0.318 |
|
| 2002 |
Nickoloff BJ, Qin JZ, Chaturvedi V, Denning MF, Bonish B, Miele L. Jagged-1 mediated activation of notch signaling induces complete maturation of human keratinocytes through NF-κB and PPARγ Cell Death and Differentiation. 9: 842-855. PMID 12107827 DOI: 10.1038/Sj.Cdd.4401036 |
0.324 |
|
| 2001 |
Cheng P, Zlobin A, Volgina V, Gottipati S, Osborne B, Simel EJ, Miele L, Gabrilovichz DI. Notch-1 regulates NF-κB activity in hemopoietic progenitor cells Journal of Immunology. 167: 4458-4467. PMID 11591772 DOI: 10.4049/Jimmunol.167.8.4458 |
0.319 |
|
| 2001 |
Rangarajan A, Talora C, Okuyama R, Nicolas M, Mammucari C, Oh H, Aster JC, Krishna S, Metzger D, Chambon P, Miele L, Aguet M, Radtke F, Dotto GP. Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation. The Embo Journal. 20: 3427-36. PMID 11432830 DOI: 10.1093/Emboj/20.13.3427 |
0.452 |
|
| 2000 |
Zlobin A, Jang M, Miele L. Toward the rational design of cell fate modifiers: notch signaling as a target for novel biopharmaceuticals Current Pharmaceutical Biotechnology. 1: 83-106. PMID 11467364 |
0.374 |
|
| 2000 |
Jang MS, Zlobin A, Kast WM, Miele L. Notch signaling as a target in multimodality cancer therapy Current Opinion in Molecular Therapeutics. 2: 55-65. PMID 11249652 |
0.41 |
|
| 2000 |
Miele L. Bioactive peptides derived from uteroglobin Annals of the New York Academy of Sciences. 923: 128-140. PMID 11193751 DOI: 10.1111/J.1749-6632.2000.Tb05524.X |
0.302 |
|
| 2000 |
Peri A, Bonaccorsi L, Muratori M, Luconi M, Baldi E, Granchi S, Pesciullesi A, Mini E, Cioppi F, Forti G, Serio M, Miele L, Maggi M. Uteroglobin reverts the transformed phenotype in the endometrial adenocarcinoma cell line HEC-1A by disrupting the metabolic pathways generating platelet-activating factor International Journal of Cancer. 88: 525-534. PMID 11058867 DOI: 10.1002/1097-0215(20001115)88:4<525::Aid-Ijc3>3.0.Co;2-Z |
0.398 |
|
| 2000 |
Yasutomo K, Doyle C, Miele L, Germain RN. The duration of antigen receptor signalling determines CD4+ versus CD8+ T-cell lineage fate Nature. 404: 506-510. PMID 10761920 DOI: 10.1038/35006664 |
0.331 |
|
| 1999 |
Miele L, Osborne B. Arbiter of differentiation and death: Notch signaling meets apoptosis Journal of Cellular Physiology. 181: 393-409. PMID 10528225 DOI: 10.1002/(Sici)1097-4652(199912)181:3<393::Aid-Jcp3>3.0.Co;2-6 |
0.38 |
|
| 1999 |
Shelly LL, Fuchs C, Miele L. Notch-1 inhibits apoptosis in murine erythroleukemia cells and is necessary for differentiation induced by hybrid polar compounds Journal of Cellular Biochemistry. 73: 164-175. PMID 10227380 DOI: 10.1002/(SICI)1097-4644(19990501)73:2<164::AID-JCB3>3.0.CO;2-0 |
0.373 |
|
| 1994 |
Peri A, Cowan BD, Bhartiya D, Miele L, Nieman LK, Nwaeze IO, Mukherjee AB. Expression of Clara cell 10-kD gene in the human endometrium and its relationship to ovarian menstrual cycle Dna and Cell Biology. 13: 495-503. PMID 7517678 DOI: 10.1089/Dna.1994.13.495 |
0.327 |
|
| 1991 |
Miele L, Strack B, Kruft V, Lanka E. Gene organization and nucleotide sequence of the primase region of incp plasmids RP4 and r751 Mitochondrial Dna. 2: 145-162. PMID 1818755 DOI: 10.3109/10425179109039685 |
0.506 |
|
| 1987 |
Pansegrau W, Miele L, Lurz R, Lanka E. Nucleotide sequence of the kanamycin resistance determinant of plasmid RP4: Homology to other aminoglycoside 3′-phosphotransferases Plasmid. 18: 193-204. PMID 2832861 DOI: 10.1016/0147-619X(87)90062-X |
0.487 |
|
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