| Year |
Citation |
Score |
| 2021 |
Bou-Nader C, Stull FW, Pecqueur L, Simon P, Guérineau V, Royant A, Fontecave M, Lombard M, Palfey BA, Hamdane D. An enzymatic activation of formaldehyde for nucleotide methylation. Nature Communications. 12: 4542. PMID 34315871 DOI: 10.1038/s41467-021-24756-8 |
0.371 |
|
| 2021 |
Tararina MA, Dam KK, Dhingra M, Janda KD, Palfey BA, Allen KN. Fast Kinetics Reveals Rate-Limiting Oxidation and the Role of the Aromatic Cage in the Mechanism of the Nicotine-Degrading Enzyme NicA2. Biochemistry. PMID 33464876 DOI: 10.1021/acs.biochem.0c00855 |
0.458 |
|
| 2020 |
Kaneshiro AK, Koebke KJ, Zhao C, Ferguson KL, Ballou DP, Palfey BA, Ruotolo BT, Marsh ENG. Kinetic Analysis of Transient Intermediates in the Mechanism of Prenyl-Flavin-Dependent Ferulic Acid Decarboxylase. Biochemistry. PMID 33342208 DOI: 10.1021/acs.biochem.0c00856 |
0.467 |
|
| 2020 |
Sanchez M, Tavassoli A, Palfey B, Vey J. Preliminary biochemical characterization of Flavin Dependent Monooxygenase DszA The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.06872 |
0.347 |
|
| 2020 |
Huynh K, Hardin T, Guzman L, Castillejo N, Palfey B, Vey J. Flavin binding affinity and initial kinetic characterization of DnmZ, a flavin‐dependent N‐oxygenase The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04331 |
0.325 |
|
| 2019 |
Motiwala HF, Kuo YH, Stinger BL, Palfey BA, Martin BR. Tunable heteroaromatic sulfones enhance in-cell cysteine profiling. Journal of the American Chemical Society. PMID 31881155 DOI: 10.1021/Jacs.9B08831 |
0.383 |
|
| 2019 |
Benítez AR, Tweedy S, Baker Dockrey SA, Lukowski AL, Wymore T, Khare D, Brooks CL, Palfey BA, Smith JL, Narayan ARH. Structural basis for selectivity in flavin-dependent monooxygenase-catalyzed oxidative dearomatization. Acs Catalysis. 9: 3633-3640. PMID 31346489 DOI: 10.1021/Acscatal.8B04575 |
0.453 |
|
| 2018 |
Saleem-Batcha R, Stull F, Sanders JN, Moore BS, Palfey BA, Houk KN, Teufel R. Enzymatic control of dioxygen binding and functionalization of the flavin cofactor. Proceedings of the National Academy of Sciences of the United States of America. PMID 29686059 DOI: 10.2210/Pdb6Fow/Pdb |
0.466 |
|
| 2017 |
Piano V, Palfey BA, Mattevi A. Flavins as Covalent Catalysts: New Mechanisms Emerge. Trends in Biochemical Sciences. PMID 28274732 DOI: 10.1016/J.Tibs.2017.02.005 |
0.43 |
|
| 2016 |
Gonzalez-Osorio L, Luong K, Jirde S, Palfey BA, Vey JL. Initial investigations of C4a-(hydro)peroxyflavin intermediate formation by dibenzothiophene monooxygenase. Biochemical and Biophysical Research Communications. PMID 27815073 DOI: 10.1016/J.Bbrc.2016.10.145 |
0.499 |
|
| 2016 |
Stull FW, Bernard SM, Sapra A, Smith JL, Zuiderweg ER, Palfey BA. Deprotonations in the Reaction of Flavin-Dependent Thymidylate Synthase. Biochemistry. PMID 27214228 DOI: 10.1021/Acs.Biochem.6B00510 |
0.536 |
|
| 2015 |
Teufel R, Stull F, Meehan MJ, Michaudel Q, Dorrestein PC, Palfey B, Moore BS. Biochemical Establishment and Characterization of EncM's Flavin-N5-oxide Cofactor. Journal of the American Chemical Society. 137: 8078-85. PMID 26067765 DOI: 10.1021/Jacs.5B03983 |
0.418 |
|
| 2015 |
Maenpuen S, Amornwatcharapong W, Krasatong P, Sucharitakul J, Palfey BA, Yuthavong Y, Chitnumsub P, Leartsakulpanich U, Chaiyen P. Kinetic mechanism and the rate-limiting step of Plasmodium vivax serine hydroxymethyltransferase. The Journal of Biological Chemistry. 290: 8656-65. PMID 25678710 DOI: 10.1074/Jbc.M114.612275 |
0.466 |
|
| 2014 |
Conrad JA, Ortiz-Maldonado M, Hoppe SW, Palfey BA. Detection of intermediates in the oxidative half-reaction of the FAD-dependent thymidylate synthase from Thermotoga maritima: carbon transfer without covalent pyrimidine activation. Biochemistry. 53: 5199-207. PMID 25068636 DOI: 10.1021/Bi500648N |
0.782 |
|
| 2013 |
Teufel R, Miyanaga A, Michaudel Q, Stull F, Louie G, Noel JP, Baran PS, Palfey B, Moore BS. Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement. Nature. 503: 552-6. PMID 24162851 DOI: 10.1038/Nature12643 |
0.49 |
|
| 2013 |
McDonald CA, Liu YY, Palfey BA. Actin stimulates reduction of the MICAL-2 monooxygenase domain. Biochemistry. 52: 6076-84. PMID 23927065 DOI: 10.1021/Bi4008462 |
0.478 |
|
| 2013 |
Prongjit M, Sucharitakul J, Palfey BA, Chaiyen P. Oxidation mode of pyranose 2-oxidase is controlled by pH. Biochemistry. 52: 1437-45. PMID 23356577 DOI: 10.1021/Bi301442X |
0.442 |
|
| 2013 |
Palfey BA. Flavoenzymes in pyrimidine metabolism Handbook of Flavoproteins: Complex Flavoproteins, Dehydrogenases and Physical Methods. 2: 203-224. DOI: 10.1515/9783110298345.203 |
0.454 |
|
| 2012 |
Mishanina TV, Koehn EM, Conrad JA, Palfey BA, Lesley SA, Kohen A. Trapping of an intermediate in the reaction catalyzed by flavin-dependent thymidylate synthase. Journal of the American Chemical Society. 134: 4442-8. PMID 22295882 DOI: 10.1021/Ja2120822 |
0.766 |
|
| 2011 |
McDonald CA, Fagan RL, Collard F, Monnier VM, Palfey BA. Oxygen reactivity in flavoenzymes: context matters. Journal of the American Chemical Society. 133: 16809-11. PMID 21958058 DOI: 10.1021/Ja2081873 |
0.778 |
|
| 2011 |
Collard F, Fagan RL, Zhang J, Nemet I, Palfey BA, Monnier VM. The cation-π interaction between Lys53 and the flavin of fructosamine oxidase (FAOX-II) is critical for activity. Biochemistry. 50: 7977-86. PMID 21755947 DOI: 10.1021/Bi1020666 |
0.804 |
|
| 2011 |
McDonald CA, Palfey BA. Substrate binding and reactivity are not linked: grafting a proton-transfer network into a Class 1A dihydroorotate dehydrogenase. Biochemistry. 50: 2714-6. PMID 21401078 DOI: 10.1021/Bi200258Y |
0.413 |
|
| 2010 |
Purcell EB, McDonald CA, Palfey BA, Crosson S. An analysis of the solution structure and signaling mechanism of LovK, a sensor histidine kinase integrating light and redox signals. Biochemistry. 49: 6761-70. PMID 20593779 DOI: 10.1021/Bi1006404 |
0.304 |
|
| 2010 |
Palfey BA, McDonald CA. Control of catalysis in flavin-dependent monooxygenases. Archives of Biochemistry and Biophysics. 493: 26-36. PMID 19944667 DOI: 10.1016/J.Abb.2009.11.028 |
0.401 |
|
| 2010 |
Fagan RL, Palfey BA. Flavin-dependent enzymes Comprehensive Natural Products Ii: Chemistry and Biology. 7: 37-113. |
0.769 |
|
| 2009 |
Kow RL, Whicher JR, McDonald CA, Palfey BA, Fagan RL. Disruption of the proton relay network in the class 2 dihydroorotate dehydrogenase from Escherichia coli. Biochemistry. 48: 9801-9. PMID 19694481 DOI: 10.1021/Bi901024M |
0.785 |
|
| 2009 |
Binter A, Staunig N, Jelesarov I, Lohner K, Palfey BA, Deller S, Gruber K, Macheroux P. A single intersubunit salt bridge affects oligomerization and catalytic activity in a bacterial quinone reductase. The Febs Journal. 276: 5263-74. PMID 19682074 DOI: 10.1111/J.1742-4658.2009.07222.X |
0.45 |
|
| 2009 |
Sollner S, Deller S, Macheroux P, Palfey BA. Mechanism of flavin reduction and oxidation in the redox-sensing quinone reductase Lot6p from Saccharomyces cerevisiae. Biochemistry. 48: 8636-43. PMID 19618916 DOI: 10.1021/Bi900734A |
0.623 |
|
| 2009 |
Fagan RL, Palfey BA. Roles in binding and chemistry for conserved active site residues in the class 2 dihydroorotate dehydrogenase from Escherichia coli. Biochemistry. 48: 7169-78. PMID 19530672 DOI: 10.1021/Bi900370S |
0.807 |
|
| 2009 |
Koehn EM, Fleischmann T, Conrad JA, Palfey BA, Lesley SA, Mathews II, Kohen A. An unusual mechanism of thymidylate biosynthesis in organisms containing the thyX gene Nature. 458: 919-923. PMID 19370033 DOI: 10.1038/Nature07973 |
0.751 |
|
| 2009 |
Rider LW, Ottosen MB, Gattis SG, Palfey BA. Mechanism of dihydrouridine synthase 2 from yeast and the importance of modifications for efficient tRNA reduction. The Journal of Biological Chemistry. 284: 10324-33. PMID 19139092 DOI: 10.1074/Jbc.M806137200 |
0.739 |
|
| 2009 |
Sollner S, Schober M, Wagner A, Prem A, Lorkova L, Palfey BA, Groll M, Macheroux P. Quinone reductase acts as a redox switch of the 20S yeast proteasome. Embo Reports. 10: 65-70. PMID 19029946 DOI: 10.1038/Embor.2008.218 |
0.365 |
|
| 2008 |
Padovani D, Labunska T, Palfey BA, Ballou DP, Banerjee R. Adenosyltransferase tailors and delivers coenzyme B12 Nature Chemical Biology. 4: 194-196. PMID 18264093 DOI: 10.1038/Nchembio.67 |
0.482 |
|
| 2007 |
Wolfe AE, Thymark M, Gattis SG, Fagan RL, Hu YC, Johansson E, Arent S, Larsen S, Palfey BA. Interaction of benzoate pyrimidine analogues with class 1A dihydroorotate dehydrogenase from Lactococcus lactis. Biochemistry. 46: 5741-53. PMID 17444658 DOI: 10.1021/Bi7001554 |
0.77 |
|
| 2007 |
Levin I, Mevarech M, Palfey BA. Characterization of a novel bifunctional dihydropteroate synthase/dihydropteroate reductase enzyme from Helicobacter pylori. Journal of Bacteriology. 189: 4062-9. PMID 17416665 DOI: 10.1128/Jb.01878-06 |
0.457 |
|
| 2007 |
Fagan RL, Jensen KF, Björnberg O, Palfey BA. Mechanism of flavin reduction in the class 1A dihydroorotate dehydrogenase from Lactococcus lactis. Biochemistry. 46: 4028-36. PMID 17341096 DOI: 10.1021/Bi602460N |
0.799 |
|
| 2007 |
Sollner S, Nebauer R, Ehammer H, Prem A, Deller S, Palfey BA, Daum G, Macheroux P. Lot6p from Saccharomyces cerevisiae is a FMN-dependent reductase with a potential role in quinone detoxification. The Febs Journal. 274: 1328-39. PMID 17298444 DOI: 10.1111/J.1742-4658.2007.05682.X |
0.506 |
|
| 2006 |
Fagan RL, Nelson MN, Pagano PM, Palfey BA. Mechanism of flavin reduction in class 2 dihydroorotate dehydrogenases. Biochemistry. 45: 14926-32. PMID 17154530 DOI: 10.1021/Bi060919G |
0.798 |
|
| 2006 |
Palfey BA, Fagan RL. Analysis of the kinetic isotope effects on initial rates in transient kinetics. Biochemistry. 45: 13631-40. PMID 17087517 DOI: 10.1021/Bi061214H |
0.757 |
|
| 2006 |
Bauer H, Fritz-Wolf K, Winzer A, Kühner S, Little S, Yardley V, Vezin H, Palfey B, Schirmer RH, Davioud-Charvet E. A fluoro analogue of the menadione derivative 6-[2'-(3'-methyl)-1',4'-naphthoquinolyl]hexanoic acid is a suicide substrate of glutathione reductase. Crystal structure of the alkylated human enzyme. Journal of the American Chemical Society. 128: 10784-94. PMID 16910673 DOI: 10.1021/Ja061155V |
0.461 |
|
| 2006 |
Shi J, Dertouzos J, Gafni A, Steel D, Palfey BA. Single-molecule kinetics reveals signatures of half-sites reactivity in dihydroorotate dehydrogenase A catalysis. Proceedings of the National Academy of Sciences of the United States of America. 103: 5775-80. PMID 16585513 DOI: 10.1073/Pnas.0510482103 |
0.436 |
|
| 2005 |
Brender JR, Dertouzos J, Ballou DP, Massey V, Palfey BA, Entsch B, Steel DG, Gafni A. Conformational dynamics of the isoalloxazine in substrate-free p-hydroxybenzoate hydroxylase: single-molecule studies. Journal of the American Chemical Society. 127: 18171-8. PMID 16366570 DOI: 10.1021/Ja055171O |
0.441 |
|
| 2005 |
Frederick KK, Palfey BA. Kinetics of proton-linked flavin conformational changes in p-hydroxybenzoate hydroxylase. Biochemistry. 44: 13304-14. PMID 16201756 DOI: 10.1021/Bi051119T |
0.525 |
|
| 2005 |
Gattis SG, Palfey BA. Direct observation of the participation of flavin in product formation by thyX-encoded thymidylate synthase. Journal of the American Chemical Society. 127: 832-3. PMID 15656610 DOI: 10.1021/Ja0432214 |
0.572 |
|
| 2004 |
Shi J, Palfey BA, Dertouzos J, Jensen KF, Gafni A, Steel D. Multiple states of the Tyr318Leu mutant of dihydroorotate dehydrogenase revealed by single-molecule kinetics. Journal of the American Chemical Society. 126: 6914-22. PMID 15174861 DOI: 10.1021/Ja038902Y |
0.443 |
|
| 2004 |
Zheng Y, Carey PR, Palfey BA. Raman spectrum of fully reduced flavin Journal of Raman Spectroscopy. 35: 521-524. DOI: 10.1002/Jrs.1218 |
0.307 |
|
| 2003 |
Palfey BA, Murthy YV, Massey V. Altered balance of half-reactions in p-hydroxybenzoate hydroxylase caused by substituting the 2'-carbon of FAD with fluorine. The Journal of Biological Chemistry. 278: 22210-6. PMID 12684497 DOI: 10.1074/Jbc.M301830200 |
0.512 |
|
| 2003 |
Argyrou A, Sun G, Palfey BA, Blanchard JS. Catalysis of diaphorase reactions by Mycobacterium tuberculosis lipoamide dehydrogenase occurs at the EH4 level. Biochemistry. 42: 2218-28. PMID 12590611 DOI: 10.1021/Bi020654F |
0.553 |
|
| 2002 |
Argyrou A, Blanchard JS, Palfey BA. The lipoamide dehydrogenase from Mycobacterium tuberculosis permits the direct observation of flavin intermediates in catalysis. Biochemistry. 41: 14580-90. PMID 12463758 DOI: 10.1021/Bi020376K |
0.424 |
|
| 2002 |
Ottosen MB, Björnberg O, Nørager S, Larsen S, Palfey BA, Jensen KF. The dimeric dihydroorotate dehydrogenase A from Lactococcus lactis dissociates reversibly into inactive monomers. Protein Science : a Publication of the Protein Society. 11: 2575-83. PMID 12381841 DOI: 10.1110/Ps.0220302 |
0.51 |
|
| 2002 |
Palfey BA, Basu R, Frederick KK, Entsch B, Ballou DP. Role of protein flexibility in the catalytic cycle of p-hydroxybenzoate hydroxylase elucidated by the Pro293Ser mutant Biochemistry. 41: 8438-8446. PMID 12081493 DOI: 10.1021/Bi012073G |
0.472 |
|
| 2001 |
Wu X, Palfey BA, Mossine VV, Monnier VM. Kinetic studies, mechanism, and substrate specificity of amadoriase I from Aspergillus sp. Biochemistry. 40: 12886-95. PMID 11669625 DOI: 10.1021/Bi011244E |
0.544 |
|
| 2001 |
Palfey BA, Björnberg O, Jensen KF. Specific inhibition of a family 1A dihydroorotate dehydrogenase by benzoate pyrimidine analogues. Journal of Medicinal Chemistry. 44: 2861-4. PMID 11520193 DOI: 10.1021/Jm015535X |
0.345 |
|
| 2001 |
Björnberg O, Jordan DB, Palfey BA, Jensen KF. Dihydrooxonate is a substrate of dihydroorotate dehydrogenase (DHOD) providing evidence for involvement of cysteine and serine residues in base catalysis. Archives of Biochemistry and Biophysics. 391: 286-94. PMID 11437361 DOI: 10.1006/Abbi.2001.2409 |
0.59 |
|
| 2001 |
Frederick KK, Ballou DP, Palfey BA. Protein dynamics control proton transfers to the substrate on the His72Asn mutant of p-hydroxybenzoate hydroxylase Biochemistry. 40: 3891-3899. PMID 11300768 DOI: 10.1021/Bi001851M |
0.557 |
|
| 2001 |
Palfey BA, Björnberg O, Jensen KF. Insight into the chemistry of flavin reduction and oxidation in Escherichia coli dihydroorotate dehydrogenase obtained by rapid reaction studies. Biochemistry. 40: 4381-90. PMID 11284694 DOI: 10.1021/Bi0025666 |
0.582 |
|
| 2001 |
Zheng Y, Massey V, Schaller A, Palfey BA, Carey PR. Comparison of resonance Raman spectra of flavin-3,4-dihydroxybenzoate charge-transfer complexes in three flavoenzymes Journal of Raman Spectroscopy. 32: 579-586. DOI: 10.1002/Jrs.738 |
0.302 |
|
| 2000 |
Ridder L, Palfey BA, Vervoort J, Rietjens IMCM. Modelling flavin and substrate substituent effects on the activation barrier and rate of oxygen transfer by p-hydroxybenzoate hydroxylase Febs Letters. 478: 197-201. PMID 10922496 DOI: 10.1016/S0014-5793(00)01844-5 |
0.5 |
|
| 2000 |
Yorita K, Misaki H, Palfey BA, Massey V. On the interpretation of quantitative structure-function activity relationship data for lactate oxidase. Proceedings of the National Academy of Sciences of the United States of America. 97: 2480-5. PMID 10706608 DOI: 10.1073/Pnas.040559797 |
0.573 |
|
| 1999 |
Moran GR, Entsch B, Palfey BA, Ballou DP. Mechanistic insights into p-hydroxybenzoate hydroxylase from studies of the mutant Ser212Ala. Biochemistry. 38: 6292-9. PMID 10320359 DOI: 10.1021/Bi990021+ |
0.554 |
|
| 1999 |
Palfey BA, Moran GR, Entsch B, Ballou DP, Massey V. Substrate recognition by "password" in p-hydroxybenzoate hydroxylase. Biochemistry. 38: 1153-8. PMID 9930974 DOI: 10.1021/Bi9826613 |
0.43 |
|
| 1997 |
Palfey BA, Ballou DP, Massey V. Flavin conformational changes in the catalytic cycle of p-hydroxybenzoate hydroxylase substituted with 6-azido- and 6-aminoflavin adenine dinucleotide. Biochemistry. 36: 15713-23. PMID 9398300 DOI: 10.1021/Bi971427U |
0.497 |
|
| 1997 |
Clarkson J, Palfey BA, Carey PR. Probing the chemistries of the substrate and flavin ring system of p- hydroxybenzoate hydroxylase by Raman difference spectroscopy Biochemistry. 36: 12560-12566. PMID 9376361 DOI: 10.1021/Bi9715270 |
0.402 |
|
| 1997 |
Yorita K, Janko K, Aki K, Ghisla S, Palfey BA, Massey V. On the reaction mechanism of L-lactate oxidase: quantitative structure-activity analysis of the reaction with para-substituted L-mandelates. Proceedings of the National Academy of Sciences of the United States of America. 94: 9590-5. PMID 9275167 DOI: 10.1073/Pnas.94.18.9590 |
0.403 |
|
| 1997 |
Moran GR, Entsch B, Palfey BA, Ballou DP. Electrostatic effects on substrate activation in para-hydroxybenzoate hydroxylase: studies of the mutant lysine 297 methionine. Biochemistry. 36: 7548-56. PMID 9200706 DOI: 10.1021/Bi9706327 |
0.557 |
|
| 1996 |
Moran GR, Entsch B, Palfey BA, Ballou DP. Evidence for flavin movement in the function of p-hydroxybenzoate hydroxylase from studies of the mutant Arg220Lys. Biochemistry. 35: 9278-85. PMID 8703933 DOI: 10.1021/Bi960360S |
0.523 |
|
| 1995 |
Zhang ZY, Palfey BA, Wu L, Zhao Y. Catalytic function of the conserved hydroxyl group in the protein tyrosine phosphatase signature motif Biochemistry. 34: 16389-16396. PMID 8845365 DOI: 10.1021/Bi00050A020 |
0.488 |
|
| 1994 |
Lah MS, Palfey BA, Schreuder HA, Ludwig ML. Crystal structures of mutant Pseudomonas aeruginosa p-hydroxybenzoate hydroxylases: the Tyr201Phe, Tyr385Phe, and Asn300Asp variants. Biochemistry. 33: 1555-64. PMID 8312276 DOI: 10.1021/Bi00172A036 |
0.44 |
|
| 1994 |
Palfey BA, Entsch B, Ballou DP, Massey V. Changes in the catalytic properties of p-hydroxybenzoate hydroxylase caused by the mutation Asn300Asp. Biochemistry. 33: 1545-54. PMID 8312275 DOI: 10.1021/Bi00172A035 |
0.581 |
|
| 1994 |
Gatti DL, Palfey BA, Lah MS, Entsch B, Massey V, Ballou DP, Ludwig ML. The mobile flavin of 4-OH benzoate hydroxylase. Science (New York, N.Y.). 266: 110-4. PMID 7939628 DOI: 10.1126/Science.7939628 |
0.515 |
|
| 1991 |
Entsch B, Palfey BA, Ballou DP, Massey V. Catalytic function of tyrosine residues in para-hydroxybenzoate hydroxylase as determined by the study of site-directed mutants. The Journal of Biological Chemistry. 266: 17341-9. PMID 1910043 |
0.458 |
|
| 1990 |
Wade PA, Bereznak JF, Palfey BA, Carroll PJ, Dailey WP, Sivasubramanian S. Diastereofacial selectivity studies on 3-alkenyl-4,5-diphenyl-4,5-dihydroisoxazoles Journal of Organic Chemistry. 55: 3045-3051. DOI: 10.1021/Jo00297A018 |
0.309 |
|
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