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Shane M. Harding, Ph.D. - Publications

Affiliations: 
2012 Medical Biophysics University of Toronto, Toronto, ON, Canada 
Area:
Molecular Biology, Cell Biology, Biochemistry, Oncology, General Biophysics
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25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 MacDonald KM, Khan S, Lin B, Hurren R, Schimmer AD, Kislinger T, Harding SM. The proteomic landscape of genotoxic stress-induced micronuclei. Molecular Cell. PMID 38423013 DOI: 10.1016/j.molcel.2024.02.001  0.325
2023 Ha CT, Tageldein MM, Harding SM. The entanglement of DNA damage and pattern recognition receptor signaling. Dna Repair. 133: 103595. PMID 37988925 DOI: 10.1016/j.dnarep.2023.103595  0.444
2020 Chen J, Harding SM, Natesan R, Tian L, Benci JL, Li W, Minn AJ, Asangani IA, Greenberg RA. Cell Cycle Checkpoints Cooperate to Suppress DNA- and RNA-Associated Molecular Pattern Recognition and Anti-Tumor Immune Responses. Cell Reports. 32: 108080. PMID 32877684 DOI: 10.1016/J.Celrep.2020.108080  0.447
2020 MacDonald KM, Benguerfi S, Harding SM. Alerting the immune system to DNA damage: micronuclei as mediators. Essays in Biochemistry. PMID 32844183 DOI: 10.1042/Ebc20200016  0.538
2018 Pfeifer CR, Xia Y, Zhu K, Liu D, Irianto J, García VMM, Millán LMS, Niese B, Harding S, Deviri D, Greenberg RA, Discher DE. Constricted migration increases DNA damage and independently represses cell cycle. Molecular Biology of the Cell. mbcE18020079. PMID 29742017 DOI: 10.1091/Mbc.E18-02-0079  0.515
2018 Irianto J, Xia Y, Pfeifer CR, Athirasala A, Ji J, Alvey CM, Tewari M, Bennett RR, Harding SM, Liu AJ, Greenberg RA, Discher DE. Repair Factor Loss and Genome Variation in Cancer Cell Invasion Biophysical Journal. 114: 653a. DOI: 10.1016/J.Bpj.2017.11.3526  0.376
2017 Harding SM, Benci JL, Irianto J, Discher DE, Minn AJ, Greenberg RA. Mitotic progression following DNA damage enables pattern recognition within micronuclei. Nature. PMID 28759889 DOI: 10.1038/Nature23470  0.475
2017 Irianto J, Xia Y, Pfeifer CR, Athirasala A, Ji J, Alvey CA, Tewari M, Bennett RR, Harding SM, Liu AJ, Greenberg RA, Discher DE. Genomic Variation in an Osteosarcoma Cell Line Caused by Pore Migration Biophysical Journal. 112: 123a. DOI: 10.1016/J.Bpj.2016.11.689  0.523
2016 Irianto J, Xia Y, Pfeifer CR, Athirasala A, Ji J, Alvey C, Tewari M, Bennett RR, Harding SM, Liu AJ, Greenberg RA, Discher DE. DNA Damage Follows Repair Factor Depletion and Portends Genome Variation in Cancer Cells after Pore Migration. Current Biology : Cb. PMID 27989676 DOI: 10.1016/J.Cub.2016.11.049  0.549
2016 Harding SM, Greenberg RA. Choreographing the Double Strand Break Response: Ubiquitin and SUMO Control of Nuclear Architecture. Frontiers in Genetics. 7: 103. PMID 27375678 DOI: 10.3389/Fgene.2016.00103  0.421
2015 Harding SM, Boiarsky JA, Greenberg RA. ATM Dependent Silencing Links Nucleolar Chromatin Reorganization to DNA Damage Recognition. Cell Reports. 13: 251-9. PMID 26440899 DOI: 10.1016/J.Celrep.2015.08.085  0.528
2015 El Ghamrasni S, Cardoso R, Halaby MJ, Zeegers D, Harding S, Kumareswaran R, Yavorska T, Chami N, Jurisicova A, Sanchez O, Hande MP, Bristow R, Hakem R, Hakem A. Cooperation of Blm and Mus81 in development, fertility, genomic integrity and cancer suppression. Oncogene. 34: 1780-9. PMID 24858046 DOI: 10.1038/Onc.2014.121  0.468
2014 Cui L, Tse K, Zahedi P, Harding SM, Zafarana G, Jaffray DA, Bristow RG, Allen C. Hypoxia and cellular localization influence the radiosensitizing effect of gold nanoparticles (AuNPs) in breast cancer cells. Radiation Research. 182: 475-88. PMID 25361396 DOI: 10.1667/Rr13642.1  0.573
2014 Shibata A, Moiani D, Arvai AS, Perry J, Harding SM, Genois MM, Maity R, van Rossum-Fikkert S, Kertokalio A, Romoli F, Ismail A, Ismalaj E, Petricci E, Neale MJ, Bristow RG, et al. DNA double-strand break repair pathway choice is directed by distinct MRE11 nuclease activities. Molecular Cell. 53: 7-18. PMID 24316220 DOI: 10.1016/J.Molcel.2013.11.003  0.613
2014 Shibata A, Moiani D, Arvai AS, Perry J, Harding SM, Genois MM, Maity R, Rossum-Fikkert Sv, Kertokalio A, Romoli F, Ismail A, Ismalaj E, Petricci E, Neale MJ, Bristow RG, et al. Erratum DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities. [Molecular Cell 53, 9, (2014) 7-18] Molecular Cell. 53. DOI: 10.1016/J.Molcel.2014.01.008  0.619
2012 Harding SM, Bristow RG. Discordance between phosphorylation and recruitment of 53BP1 in response to DNA double-strand breaks. Cell Cycle (Georgetown, Tex.). 11: 1432-44. PMID 22421153 DOI: 10.4161/Cc.19824  0.64
2012 Bristow R, Kumareswaran R, Harding S, Chan N. SP-0029 EXPLOITING HYPOXIA DEPENDENT DNA REPAIR DEFECTS Radiotherapy and Oncology. 103: S11. DOI: 10.1016/S0167-8140(12)70368-7  0.427
2011 Mothersill C, Bristow RG, Harding SM, Smith RW, Mersov A, Seymour CB. A role for p53 in the response of bystander cells to receipt of medium borne signals from irradiated cells. International Journal of Radiation Biology. 87: 1120-5. PMID 21831006 DOI: 10.3109/09553002.2011.610866  0.493
2011 Harding SM, Coackley C, Bristow RG. ATM-dependent phosphorylation of 53BP1 in response to genomic stress in oxic and hypoxic cells. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. 99: 307-12. PMID 21680038 DOI: 10.1016/J.Radonc.2011.05.039  0.619
2011 Fraser M, Harding SM, Zhao H, Coackley C, Durocher D, Bristow RG. MRE11 promotes AKT phosphorylation in direct response to DNA double-strand breaks. Cell Cycle (Georgetown, Tex.). 10: 2218-32. PMID 21623170 DOI: 10.4161/Cc.10.13.16305  0.688
2011 Al Rashid ST, Harding SM, Law C, Coackley C, Bristow RG. Protein-protein interactions occur between p53 phosphoforms and ATM and 53BP1 at sites of exogenous DNA damage. Radiation Research. 175: 588-98. PMID 21361779 DOI: 10.1667/Rr2084.1  0.599
2010 O'Donnell L, Panier S, Wildenhain J, Tkach JM, Al-Hakim A, Landry MC, Escribano-Diaz C, Szilard RK, Young JT, Munro M, Canny MD, Kolas NK, Zhang W, Harding SM, Ylanko J, et al. The MMS22L-TONSL complex mediates recovery from replication stress and homologous recombination. Molecular Cell. 40: 619-31. PMID 21055983 DOI: 10.1016/J.Molcel.2010.10.024  0.619
2010 Sanli T, Rashid A, Liu C, Harding S, Bristow RG, Cutz JC, Singh G, Wright J, Tsakiridis T. Ionizing radiation activates AMP-activated kinase (AMPK): a target for radiosensitization of human cancer cells. International Journal of Radiation Oncology, Biology, Physics. 78: 221-9. PMID 20615625 DOI: 10.1016/J.Ijrobp.2010.03.005  0.549
2010 Li L, Halaby MJ, Hakem A, Cardoso R, El Ghamrasni S, Harding S, Chan N, Bristow R, Sanchez O, Durocher D, Hakem R. Rnf8 deficiency impairs class switch recombination, spermatogenesis, and genomic integrity and predisposes for cancer. The Journal of Experimental Medicine. 207: 983-97. PMID 20385750 DOI: 10.1084/Jem.20092437  0.642
2010 Li L, Halaby M, Hakem A, Cardoso R, El Ghamrasni S, Harding S, Chan N, Bristow R, Sanchez O, Durocher D, Hakem R. Rnf8 deficiency impairs class switch recombination, spermatogenesis, and genomic integrity and predisposes for cancer The Journal of Cell Biology. 189: i6-i6. DOI: 10.1083/JCB1892OIA6  0.415
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