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Weiwei Dang, Ph.D. - Publications

Affiliations: 
2000-2006 Biochemistry and Molecular Biology Southern Illinois University at Carbondale, Carbondale, IL 
 2006-2009 The Wistar Institute, USA 
 2009-2013 Cell and Developmental Biology University of Pennsylvania, Philadelphia, PA, United States 
 2013- Huffington Center on Aging, Molecular and Human Genetics Baylor College of Medicine, Houston, TX 
Area:
Molecular Biology, Cell Biology, Genetics, Epigenetics, Aging, Stem Cells
Website:
https://www.bcm.edu/research/faculty-labs/weiwei-dang-lab
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50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Yu Y, Wang X, Fox J, Yu R, Thakre P, McCauley B, Nikoloutsos N, Yu Y, Li Q, Hastings PJ, Dang W, Chen K, Ira G. Yeast EndoG prevents genome instability by degrading extranuclear DNA species. Nature Communications. 15: 7653. PMID 39227600 DOI: 10.1038/s41467-024-52147-2  0.324
2024 Ira G, Yu Y, Wang X, Fox J, Yu R, McCauley B, Nikoloutsos N, Li Q, Hastings P, Dang W, Chen K, Thakre P. Yeast EndoG prevents genome instability by degrading cytoplasmic DNA. Research Square. PMID 38260641 DOI: 10.21203/rs.3.rs-3641411/v1  0.797
2023 Yu Y, Wang X, Fox J, Yu R, Thakre P, McCauley B, Nikoloutsos N, Li Q, Hastings PJ, Dang W, Chen K, Ira G. Yeast EndoG prevents genome instability by degrading cytoplasmic DNA. Biorxiv : the Preprint Server For Biology. PMID 38168242 DOI: 10.1101/2023.12.13.571550  0.798
2023 Yu A, Yu R, Liu H, Ge C, Dang W. SIRT1 safeguards adipogenic differentiation by orchestrating anti-oxidative responses and suppressing cellular senescence. Geroscience. PMID 37420111 DOI: 10.1007/s11357-023-00863-w  0.765
2023 McCauley BS, Dang W. Mammalian aging driven by transcription going awry. Trends in Genetics : Tig. PMID 37419698 DOI: 10.1016/j.tig.2023.06.006  0.31
2021 McCauley BS, Sun L, Yu R, Lee M, Liu H, Leeman DS, Huang Y, Webb AE, Dang W. Altered Chromatin States Drive Cryptic Transcription in Aging Mammalian Stem Cells. Nature Aging. 1: 684-697. PMID 34746802 DOI: 10.1038/s43587-021-00091-x  0.799
2021 Sun Y, Yu R, Guo HB, Qin H, Dang W. A quantitative yeast aging proteomics analysis reveals novel aging regulators. Geroscience. PMID 34241809 DOI: 10.1007/s11357-021-00412-3  0.781
2021 McCauley BS, Dang W. Loosening chromatin and dysregulated transcription: a perspective on cryptic transcription during mammalian aging. Briefings in Functional Genomics. PMID 34050364 DOI: 10.1093/bfgp/elab026  0.517
2021 Yu R, Cao X, Sun L, Zhu JY, Wasko BM, Liu W, Crutcher E, Liu H, Jo MC, Qin L, Kaeberlein M, Han Z, Dang W. Inactivating histone deacetylase HDA promotes longevity by mobilizing trehalose metabolism. Nature Communications. 12: 1981. PMID 33790287 DOI: 10.1038/s41467-021-22257-2  0.809
2021 Guo HB, Ghafari M, Dang W, Qin H. Protein interaction potential landscapes for yeast replicative aging. Scientific Reports. 11: 7143. PMID 33785798 DOI: 10.1038/s41598-021-86415-8  0.341
2021 Ghafari M, Clark J, Guo HB, Yu R, Sun Y, Dang W, Qin H. Complementary performances of convolutional and capsule neural networks on classifying microfluidic images of dividing yeast cells. Plos One. 16: e0246988. PMID 33730031 DOI: 10.1371/journal.pone.0246988  0.756
2021 Liu L, Yan Z, Osia BA, Twarowski J, Sun L, Kramara J, Lee RS, Kumar S, Elango R, Li H, Dang W, Ira G, Malkova A. Tracking break-induced replication shows that it stalls at roadblocks. Nature. PMID 33473214 DOI: 10.1038/s41586-020-03172-w  0.683
2020 Sun L, Dang W. SIRT7 slows down stem cell aging by preserving heterochromatin: a perspective on the new discovery. Protein & Cell. PMID 32435977 DOI: 10.1007/s13238-020-00735-5  0.64
2020 Yu R, Jo MC, Dang W. Measuring the Replicative Lifespan of Saccharomyces cerevisiae Using the HYAA Microfluidic Platform. Methods in Molecular Biology (Clifton, N.J.). 2144: 1-6. PMID 32410020 DOI: 10.1007/978-1-0716-0592-9_1  0.77
2020 Huang B, Zhong D, Zhu J, An Y, Gao M, Zhu S, Dang W, Wang X, Yang B, Xie Z. Inhibition of histone acetyltransferase GCN5 extends lifespan in both yeast and human cell lines. Aging Cell. e13129. PMID 32157780 DOI: 10.1111/acel.13129  0.477
2020 Moruno-Manchon JF, Lejault P, Wang Y, McCauley B, Honarpisheh P, Morales Scheihing DA, Singh S, Dang W, Kim N, Urayama A, Zhu L, Monchaud D, McCullough LD, Tsvetkov AS. Small-molecule G-quadruplex stabilizers reveal a novel pathway of autophagy regulation in neurons. Elife. 9. PMID 32043463 DOI: 10.7554/Elife.52283  0.459
2020 Yu R, McCauley B, Dang W. Loss of chromatin structural integrity is a source of stress during aging. Human Genetics. PMID 31900586 DOI: 10.1007/S00439-019-02100-X  0.803
2019 Yu A, Zhou R, Xia B, Dang W, Yang Z, Chen X. NAMPT maintains mitochondria content via NRF2-PPARα/AMPKα pathway to promote cell survival under oxidative stress. Cellular Signalling. 109496. PMID 31816398 DOI: 10.1016/j.cellsig.2019.109496  0.305
2019 Yu R, Sun L, Sun Y, Han X, Qin L, Dang W. Cellular response to moderate chromatin architectural defects promotes longevity. Science Advances. 5: eaav1165. PMID 31309140 DOI: 10.1126/Sciadv.Aav1165  0.795
2019 Tian X, Firsanov D, Zhang Z, Cheng Y, Luo L, Tombline G, Tan R, Simon M, Henderson S, Steffan J, Goldfarb A, Tam J, Zheng K, Cornwell A, Johnson A, ... ... Dang W, et al. SIRT6 Is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species. Cell. 177: 622-638.e22. PMID 31002797 DOI: 10.1016/J.Cell.2019.03.043  0.488
2019 Sen P, Lan Y, Li CY, Sidoli S, Donahue G, Dou Z, Frederick B, Chen Q, Luense LJ, Garcia BA, Dang W, Johnson FB, Adams PD, Schultz DC, Berger SL. Histone Acetyltransferase p300 Induces De Novo Super-Enhancers to Drive Cellular Senescence. Molecular Cell. PMID 30773298 DOI: 10.1016/J.Molcel.2019.01.021  0.777
2019 Moruno-Manchon JF, Lejault P, Wang Y, McCauley B, Honarpisheh P, Scheihing DAM, Singh S, Dang W, Kim N, Urayama A, Zhu L, Monchaud D, McCullough LD, Tsvetkov AS. Author response: Small-molecule G-quadruplex stabilizers reveal a novel pathway of autophagy regulation in neurons Elife. DOI: 10.7554/Elife.52283.Sa2  0.361
2019 McCauley B, Sun L, Dang W. CRYPTIC TRANSCRIPTION IS ASSOCIATED WITH AGE IN MAMMALIAN STEM CELLS Innovation in Aging. 3: S963-S963. DOI: 10.1093/Geroni/Igz038.3493  0.549
2019 Sun L, McCauley B, Dang W. YY1-MEDIATED PROMOTER-SUPER ENHANCER INTERACTIONS REGULATE MSC MULTIPOTENCY DURING REPLICATIVE AGING Innovation in Aging. 3: S912-S913. DOI: 10.1093/Geroni/Igz038.3328  0.508
2019 Yu R, Cao X, Dang W. HIGH THROUGHPUT YEAST REPLICATIVE LIFESPAN SCREEN UNCOVERS HISTONE DEACETYLASE HDA AS NOVEL REGULATOR OF AGING Innovation in Aging. 3: S876-S876. DOI: 10.1093/Geroni/Igz038.3210  0.524
2018 Beaupere C, Dinatto L, Wasko BM, Chen RB, VanValkenburg L, Kiflezghi MG, Lee MB, Promislow DEL, Dang W, Kaeberlein M, Labunskyy VM. Genetic screen identifies adaptive aneuploidy as a key mediator of ER stress resistance in yeast. Proceedings of the National Academy of Sciences of the United States of America. PMID 30185560 DOI: 10.1073/Pnas.1804264115  0.385
2018 Sun L, Yu R, Dang W. Chromatin Architectural Changes during Cellular Senescence and Aging. Genes. 9. PMID 29659513 DOI: 10.3390/Genes9040211  0.793
2017 Yu A, Dang W. Regulation of stem cell aging by SIRT1 - Linking metabolic signaling to epigenetic modifications. Molecular and Cellular Endocrinology. PMID 28392411 DOI: 10.1016/j.mce.2017.03.031  0.389
2017 Dang W. H3K36Me3 Promotes Longevity By Suppressing Age-Associated Intragenic Cryptic Transcription Innovation in Aging. 1: 134-135. DOI: 10.1093/Geroni/Igx004.544  0.506
2016 Yu R, Dang W. Gearing up for survival - HSP-containing granules accumulate in quiescent cells and promote survival. Microbial Cell (Graz, Austria). 3: 95-96. PMID 28362009 DOI: 10.15698/mic2016.03.481  0.748
2016 Molina-Serrano D, Schiza V, Demosthenous C, Stavrou E, Oppelt J, Kyriakou D, Liu W, Zisser G, Bergler H, Dang W, Kirmizis A. Loss of Nat4 and its associated histone H4 N-terminal acetylation mediates calorie restriction-induced longevity. Embo Reports. PMID 27799288 DOI: 10.15252/Embr.201642540  0.758
2016 Sun Y, Dang W. The Controversy Around Sirtuins and Their Functions in Aging Molecular Basis of Nutrition and Aging: a Volume in the Molecular Nutrition Series. 227-241. DOI: 10.1016/B978-0-12-801816-3.00017-0  0.337
2015 Jo MC, Liu W, Gu L, Dang W, Qin L. High-throughput analysis of yeast replicative aging using a microfluidic system. Proceedings of the National Academy of Sciences of the United States of America. 112: 9364-9. PMID 26170317 DOI: 10.1073/Pnas.1510328112  0.481
2015 Sen P, Dang W, Donahue G, Dai J, Dorsey J, Cao X, Liu W, Cao K, Perry R, Lee JY, Wasko BM, Carr DT, He C, Robison B, Wagner J, et al. H3K36 methylation promotes longevity by enhancing transcriptional fidelity. Genes & Development. 29: 1362-1376. PMID 26159996 DOI: 10.1101/Gad.263707.115  0.786
2015 Qin J, Rajaratnam R, Feng L, Salami J, Barber-Rotenberg JS, Domsic J, Reyes-Uribe P, Liu H, Dang W, Berger SL, Villanueva J, Meggers E, Marmorstein R. Development of organometallic S6K1 inhibitors. Journal of Medicinal Chemistry. 58: 305-14. PMID 25356520 DOI: 10.1021/Jm5011868  0.636
2014 McCormick MA, Mason AG, Guyenet SJ, Dang W, Garza RM, Ting MK, Moller RM, Berger SL, Kaeberlein M, Pillus L, La Spada AR, Kennedy BK. The SAGA histone deubiquitinase module controls yeast replicative lifespan via Sir2 interaction. Cell Reports. 8: 477-86. PMID 25043177 DOI: 10.1016/J.Celrep.2014.06.037  0.7
2014 Dang W. The controversial world of sirtuins. Drug Discovery Today. Technologies. 12: e9-e17. PMID 25027380 DOI: 10.1016/J.Ddtec.2012.08.003  0.431
2014 McCauley BS, Dang W. Histone methylation and aging: lessons learned from model systems. Biochimica Et Biophysica Acta. 1839: 1454-62. PMID 24859460 DOI: 10.1016/J.Bbagrm.2014.05.008  0.553
2014 Dang W, Sutphin GL, Dorsey JA, Otte GL, Cao K, Perry RM, Wanat JJ, Saviolaki D, Murakami CJ, Tsuchiyama S, Robison B, Gregory BD, Vermeulen M, Shiekhattar R, Johnson FB, et al. Inactivation of yeast Isw2 chromatin remodeling enzyme mimics longevity effect of calorie restriction via induction of genotoxic stress response. Cell Metabolism. 19: 952-66. PMID 24814484 DOI: 10.1016/J.Cmet.2014.04.004  0.733
2013 Tsuchiyama S, Kwan E, Dang W, Bedalov A, Kennedy BK. Sirtuins in yeast: phenotypes and tools. Methods in Molecular Biology (Clifton, N.J.). 1077: 11-37. PMID 24014397 DOI: 10.1007/978-1-62703-637-5_2  0.512
2012 Yuan H, Rossetto D, Mellert H, Dang W, Srinivasan M, Johnson J, Hodawadekar S, Ding EC, Speicher K, Abshiru N, Perry R, Wu J, Yang C, Zheng YG, Speicher DW, et al. MYST protein acetyltransferase activity requires active site lysine autoacetylation. The Embo Journal. 31: 58-70. PMID 22020126 DOI: 10.1038/Emboj.2011.382  0.68
2011 Edwards CR, Dang W, Berger SL. Histone H4 lysine 20 of Saccharomyces cerevisiae is monomethylated and functions in subtelomeric silencing. Biochemistry. 50: 10473-83. PMID 21985125 DOI: 10.1021/Bi201120Q  0.75
2010 Kozak ML, Chavez A, Dang W, Berger SL, Ashok A, Guo X, Johnson FB. Inactivation of the Sas2 histone acetyltransferase delays senescence driven by telomere dysfunction. The Embo Journal. 29: 158-70. PMID 19875981 DOI: 10.1038/Emboj.2009.314  0.719
2009 Sanders BD, Jackson B, Brent M, Taylor AM, Dang W, Berger SL, Schreiber SL, Howitz K, Marmorstein R. Identification and characterization of novel sirtuin inhibitor scaffolds. Bioorganic & Medicinal Chemistry. 17: 7031-41. PMID 19734050 DOI: 10.1016/J.Bmc.2009.07.073  0.676
2009 Dang W, Steffen KK, Perry R, Dorsey JA, Johnson FB, Shilatifard A, Kaeberlein M, Kennedy BK, Berger SL. Histone H4 lysine 16 acetylation regulates cellular lifespan. Nature. 459: 802-7. PMID 19516333 DOI: 10.1038/Nature08085  0.766
2009 Lin YY, Lu JY, Zhang J, Walter W, Dang W, Wan J, Tao SC, Qian J, Zhao Y, Boeke JD, Berger SL, Zhu H. Protein acetylation microarray reveals that NuA4 controls key metabolic target regulating gluconeogenesis. Cell. 136: 1073-84. PMID 19303850 DOI: 10.1016/J.Cell.2009.01.033  0.706
2007 Dang W, Bartholomew B. Domain architecture of the catalytic subunit in the ISW2-nucleosome complex. Molecular and Cellular Biology. 27: 8306-17. PMID 17908792 DOI: 10.1128/Mcb.01351-07  0.684
2007 Dang W, Kagalwala MN, Bartholomew B. The Dpb4 subunit of ISW2 is anchored to extranucleosomal DNA. The Journal of Biological Chemistry. 282: 19418-25. PMID 17491017 DOI: 10.1074/Jbc.M700640200  0.794
2006 Dang W, Kagalwala MN, Bartholomew B. Regulation of ISW2 by concerted action of histone H4 tail and extranucleosomal DNA. Molecular and Cellular Biology. 26: 7388-96. PMID 17015471 DOI: 10.1128/Mcb.01159-06  0.796
2004 Kagalwala MN, Glaus BJ, Dang W, Zofall M, Bartholomew B. Topography of the ISW2-nucleosome complex: insights into nucleosome spacing and chromatin remodeling. The Embo Journal. 23: 2092-104. PMID 15131696 DOI: 10.1038/Sj.Emboj.7600220  0.723
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