Ravikiran S. Yedidi, Ph.D. - Publications

2009 Biochemistry and Molecular Biology Wayne State University, Detroit, MI, United States 
Biochemistry, Medical Biophysics, Pharmacy

15 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Aoki M, Hayashi H, Yedidi RS, Martyr CD, Takamatsu Y, Aoki-Ogata H, Nakamura T, Nakata H, Das D, Yamagata Y, Ghosh AK, Mitsuya H. The C5-substituted Tetrahydropyrano-tetrahydofuran-derived Protease Inhibitors (PIs) Exert Potent Inhibition of the Replication of HIV-1 Variants Highly Resistant to Various PIs Including Darunavir. Journal of Virology. PMID 26581995 DOI: 10.1128/Jvi.01829-15  0.6
2014 Yedidi RS, Proteasa G, Martin PD, Liu Z, Vickrey JF, Kovari IA, Kovari LC. A multi-drug resistant HIV-1 protease is resistant to the dimerization inhibitory activity of TLF-PafF. Journal of Molecular Graphics & Modelling. 53: 105-11. PMID 25108107 DOI: 10.1016/j.jmgm.2014.06.010  0.6
2014 Yedidi RS, Garimella H, Aoki M, Aoki-Ogata H, Desai DV, Chang SB, Davis DA, Fyvie WS, Kaufman JD, Smith DW, Das D, Wingfield PT, Maeda K, Ghosh AK, Mitsuya H. A conserved hydrogen-bonding network of P2 bis-tetrahydrofuran-containing HIV-1 protease inhibitors (PIs) with a protease active-site amino acid backbone aids in their activity against PI-resistant HIV. Antimicrobial Agents and Chemotherapy. 58: 3679-88. PMID 24752271 DOI: 10.1128/Aac.00107-14  0.6
2014 Yedidi RS, Liu Z, Kovari IA, Woster PM, Kovari LC. P1 and P1′ para-fluoro phenyl groups show enhanced binding and favorable predicted pharmacological properties: Structure-based virtual screening of extended lopinavir analogs against multi-drug resistant HIV-1 protease Journal of Molecular Graphics and Modelling. 47: 18-24. PMID 24291501 DOI: 10.1016/J.Jmgm.2013.10.010  0.6
2013 Yedidi RS, Muhuhi JM, Liu Z, Bencze KZ, Koupparis K, O'Connor CE, Kovari IA, Spaller MR, Kovari LC. Design, synthesis and evaluation of a potent substrate analog inhibitor identified by scanning Ala/Phe mutagenesis, mimicking substrate co-evolution, against multidrug-resistant HIV-1 protease. Biochemical and Biophysical Research Communications. 438: 703-8. PMID 23921229 DOI: 10.1016/J.Bbrc.2013.07.117  0.6
2013 Yedidi RS, Maeda K, Fyvie WS, Steffey M, Davis DA, Palmer I, Aoki M, Kaufman JD, Stahl SJ, Garimella H, Das D, Wingfield PT, Ghosh AK, Mitsuya H. P2' benzene carboxylic acid moiety is associated with decrease in cellular uptake: evaluation of novel nonpeptidic HIV-1 protease inhibitors containing P2 bis-tetrahydrofuran moiety. Antimicrobial Agents and Chemotherapy. 57: 4920-7. PMID 23877703 DOI: 10.1128/Aac.00868-13  0.6
2013 Liu Z, Yedidi RS, Wang Y, Dewdney TG, Reiter SJ, Brunzelle JS, Kovari IA, Kovari LC. Crystallographic study of multi-drug resistant HIV-1 protease lopinavir complex: mechanism of drug recognition and resistance. Biochemical and Biophysical Research Communications. 437: 199-204. PMID 23792096 DOI: 10.1016/J.Bbrc.2013.06.027  0.6
2013 Liu Z, Yedidi RS, Wang Y, Dewdney TG, Reiter SJ, Brunzelle JS, Kovari IA, Kovari LC. Insights into the mechanism of drug resistance: X-ray structure analysis of multi-drug resistant HIV-1 protease ritonavir complex. Biochemical and Biophysical Research Communications. 431: 232-8. PMID 23313846 DOI: 10.1016/J.Bbrc.2012.12.127  0.6
2013 Liu Z, Wang Y, Yedidi RS, Dewdney TG, Reiter SJ, Brunzelle JS, Kovari IA, Kovari LC. Conserved hydrogen bonds and water molecules in MDR HIV-1 protease substrate complexes. Biochemical and Biophysical Research Communications. 430: 1022-7. PMID 23261453 DOI: 10.1016/J.Bbrc.2012.12.045  0.6
2012 Yedidi RS, Liu Z, Wang Y, Brunzelle JS, Kovari IA, Woster PM, Kovari LC, Gupta D. Crystal structures of multidrug-resistant HIV-1 protease in complex with two potent anti-malarial compounds Biochemical and Biophysical Research Communications. 421: 413-417. PMID 22469467 DOI: 10.1016/J.Bbrc.2012.03.096  0.6
2012 Liu Z, Wang Y, Yedidi RS, Brunzelle JS, Kovari IA, Sohi J, Kamholz J, Kovari LC. Crystal structure of the extracellular domain of human myelin protein zero. Proteins. 80: 307-13. PMID 21971831 DOI: 10.1002/Prot.23164  0.6
2011 Yedidi RS, Proteasa G, Martinez JL, Vickrey JF, Martin PD, Wawrzak Z, Liu Z, Kovari IA, Kovari LC. Contribution of the 80s loop of HIV-1 protease to the multidrug-resistance mechanism: crystallographic study of MDR769 HIV-1 protease variants. Acta Crystallographica. Section D, Biological Crystallography. 67: 524-32. PMID 21636892 DOI: 10.1107/S0907444911011541  0.6
2011 Ide K, Aoki M, Amano M, Koh Y, Yedidi RS, Das D, Leschenko S, Chapsal B, Ghosh AK, Mitsuya H. Novel HIV-1 protease inhibitors (PIs) containing a bicyclic P2 functional moiety, tetrahydropyrano-tetrahydrofuran, that are potent against multi-PI-resistant HIV-1 variants. Antimicrobial Agents and Chemotherapy. 55: 1717-27. PMID 21282450 DOI: 10.1128/Aac.01540-10  0.6
2010 Gupta D, Yedidi RS, Varghese S, Kovari LC, Woster PM. Mechanism-based inhibitors of the aspartyl protease plasmepsin II as potential antimalarial agents Journal of Medicinal Chemistry. 53: 4234-4247. PMID 20438064 DOI: 10.1021/Jm100233B  0.6
2006 Ge Y, Dombkowski AA, LaFiura KM, Tatman D, Yedidi RS, Stout ML, Buck SA, Massey G, Becton DL, Weinstein HJ, Ravindranath Y, Matherly LH, Taub JW. Differential gene expression, GATA1 target genes, and the chemotherapy sensitivity of Down syndrome megakaryocytic leukemia. Blood. 107: 1570-81. PMID 16249385 DOI: 10.1182/blood-2005-06-2219  0.6
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