Year |
Citation |
Score |
2024 |
Solga D, Wieske LHE, Wilcox S, Zeilinger C, Jansen-Olliges L, Cirnski K, Hermann J, Müller R, Erdelyi M, Kirschning A. Is Simultaneous Binding to DNA and Gyrase Important for the Antibacterial Activity of Cystobactamids? Chemistry (Weinheim An Der Bergstrasse, Germany). e202303796. PMID 38217886 DOI: 10.1002/chem.202303796 |
0.417 |
|
2023 |
Wang H, Han Y, Wang X, Jia Y, Zhang Y, Müller R, Huo L. Genome Mining of Myxopeptins Reveals a Class of Lanthipeptide-Derived Linear Dehydroamino Acid-Containing Peptides from sp. MCy9171. Acs Chemical Biology. PMID 37703191 DOI: 10.1021/acschembio.3c00265 |
0.476 |
|
2023 |
Wang X, Chen X, Wang ZJ, Zhuang M, Zhong L, Fu C, Garcia R, Müller R, Zhang Y, Yan J, Wu D, Huo L. Discovery and Characterization of a Myxobacterial Lanthipeptide with Unique Biosynthetic Features and Anti-inflammatory Activity. Journal of the American Chemical Society. PMID 37466996 DOI: 10.1021/jacs.3c06014 |
0.483 |
|
2023 |
Wang ZJ, Liu X, Zhou H, Liu Y, Tu Q, Huo L, Yan F, Müller R, Zhang Y, Xu X. Engineered Biosynthesis of Complex Disorazol Polyketides in a Streamlined . Acs Synthetic Biology. PMID 36988632 DOI: 10.1021/acssynbio.2c00610 |
0.458 |
|
2023 |
Koller TO, Scheid U, Kösel T, Herrmann J, Krug D, Boshoff HIM, Beckert B, Evans JC, Schlemmer J, Sloan B, Weiner DM, Via LE, Moosa A, Ioerger TR, Graf M, et al. The Myxobacterial Antibiotic Myxovalargin: Biosynthesis, Structural Revision, Total Synthesis, and Molecular Characterization of Ribosomal Inhibition. Journal of the American Chemical Society. PMID 36603206 DOI: 10.1021/jacs.2c08816 |
0.472 |
|
2022 |
Wang ZJ, Liu X, Zhou H, Liu Y, Zhong L, Wang X, Tu Q, Huo L, Yan F, Gu L, Müller R, Zhang Y, Bian X, Xu X. Engineering of strain E264 serves as a chassis for expression of complex specialized metabolites. Frontiers in Microbiology. 13: 1073243. PMID 36466684 DOI: 10.3389/fmicb.2022.1073243 |
0.49 |
|
2021 |
Zscherp R, Coetzee J, Vornweg J, Grunenberg J, Herrmann J, Müller R, Klahn P. Biomimetic enterobactin analogue mediates iron-uptake and cargo transport into and . Chemical Science. 12: 10179-10190. PMID 34377407 DOI: 10.1039/d1sc02084f |
0.665 |
|
2020 |
Hug JJ, Dastbaz J, Adam S, Revermann O, Koehnke J, Krug D, Müller R. Biosynthesis of cittilins, unusual ribosomally synthesized and post-translationally modified peptides from . Acs Chemical Biology. PMID 32639716 DOI: 10.1021/Acschembio.0C00430 |
0.357 |
|
2020 |
Pirritano M, Zaburannyi N, Grosser K, Gasparoni G, Müller R, Simon M, Schrallhammer M. Dual-Seq reveals genome and transcriptome of Caedibacter taeniospiralis, obligate endosymbiont of Paramecium. Scientific Reports. 10: 9727. PMID 32546745 DOI: 10.1038/S41598-020-65894-1 |
0.303 |
|
2020 |
Okoth DA, Hug JJ, Garcia R, Spröer C, Overmann J, Müller R. 2-Hydroxysorangiadenosine: Structure and Biosynthesis of a Myxobacterial Sesquiterpene-Nucleoside. Molecules (Basel, Switzerland). 25. PMID 32527018 DOI: 10.3390/Molecules25112676 |
0.331 |
|
2020 |
Dahlem C, Siow WX, Lopatniuk M, Tse WKF, Kessler SM, Kirsch SH, Hoppstädter J, Vollmar AM, Müller R, Luzhetskyy A, Bartel K, Kiemer AK. Thioholgamide A, a New Anti-Proliferative Anti-Tumor Agent, Modulates Macrophage Polarization and Metabolism. Cancers. 12. PMID 32438733 DOI: 10.3390/Cancers12051288 |
0.301 |
|
2020 |
Izzat S, Rachid S, Ajdidi A, A El-Nakady Y, Liu XX, Ye BC, Müller R. The ROK like protein of Myxococcus xanthus DK1622 acts as a pleiotropic transcriptional regulator for secondary metabolism. Journal of Biotechnology. PMID 32057784 DOI: 10.1016/J.Jbiotec.2020.02.005 |
0.36 |
|
2020 |
Elgaher WAM, Hamed MM, Baumann S, Herrmann J, Siebenbürger L, Krull J, Cirnski K, Kirschning A, Brönstrup M, Müller R, Hartmann RW. Cystobactamid 507: Concise Synthesis, Mode of Action and Optimization toward More Potent Antibiotics. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 31984562 DOI: 10.1002/Chem.202000117 |
0.518 |
|
2020 |
Gross P, Seelert H, Meiser P, Müller R. Characterization of bromelain indicates a molar excess of inhibitor vs. enzyme molecules, a Jacalin-like lectin and Maillard reaction products. Journal of Pharmaceutical and Biomedical Analysis. 181: 113075. PMID 31951942 DOI: 10.1016/J.Jpba.2019.113075 |
0.302 |
|
2020 |
Zisopoulou SA, Bousis S, Haupenthal J, Herrmann J, Müller R, Hirsch AKH, Komiotis D, Gallos JK, Stathakis CI. Synthesis and Biological Evaluation of Novel 2-Substituted Analogues of (–)-Pentenomycin I Synlett. 31: 475-481. DOI: 10.1055/S-0039-1690772 |
0.332 |
|
2020 |
Testolin G, Cirnski K, Rox K, Prochnow H, Fetz V, Grandclaudon C, Mollner T, Baiyoumy A, Ritter A, Leitner C, Krull J, Heuvel Jvd, Vassort A, Sordello S, Hamed MM, et al. Synthetic studies of cystobactamids as antibiotics and bacterial imaging carriers lead to compounds with high in vivo efficacy Chemical Science. 11: 1316-1334. DOI: 10.1039/C9Sc04769G |
0.333 |
|
2020 |
Elgaher WAM, Hamed MM, Baumann S, Herrmann J, Siebenbürger L, Krull J, Cirnski K, Kirschning A, Brönstrup M, Müller R, Hartmann RW. Cover Feature: Cystobactamid 507: Concise Synthesis, Mode of Action, and Optimization toward More Potent Antibiotics (Chem. Eur. J. 32/2020) Chemistry: a European Journal. 26: 7141-7141. DOI: 10.1002/Chem.202002127 |
0.468 |
|
2019 |
Grandclaudon C, Birudukota NVS, Elgaher WAM, Jumde RP, Yahiaoui S, Arisetti N, Hennessen F, Hüttel S, Stadler M, Herrmann J, Miethke M, Hartmann RW, Müller R, Hirsch AKH, Brönstrup M. Semisynthesis and biological evaluation of amidochelocardin derivatives as broad-spectrum antibiotics. European Journal of Medicinal Chemistry. 188: 112005. PMID 31911294 DOI: 10.1016/J.Ejmech.2019.112005 |
0.311 |
|
2019 |
Siebert DCB, Sommer R, Pogorevc D, Hoffmann M, Wenzel SC, Müller R, Titz A. Chemical synthesis of tripeptide thioesters for the biotechnological incorporation into the myxobacterial secondary metabolite argyrin via mutasynthesis. Beilstein Journal of Organic Chemistry. 15: 2922-2929. PMID 31839838 DOI: 10.3762/Bjoc.15.286 |
0.34 |
|
2019 |
Kirschning A, Planke T, Cirnski K, Herrmann J, Müller R. Synthetic and Biologic Studies on New Urea and Triazole Containing Cystobactamid Derivatives. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 31834653 DOI: 10.1002/Chem.201904073 |
0.508 |
|
2019 |
Wang Q, Xie F, Tong Y, Habisch R, Yang B, Zhang L, Müller R, Fu C. Dual-function chromogenic screening-based CRISPR/Cas9 genome editing system for actinomycetes. Applied Microbiology and Biotechnology. PMID 31788711 DOI: 10.1007/S00253-019-10223-4 |
0.323 |
|
2019 |
Bader CD, Panter F, Müller R. In depth natural product discovery - Myxobacterial strains that provided multiple secondary metabolites. Biotechnology Advances. 107480. PMID 31707075 DOI: 10.1016/J.Biotechadv.2019.107480 |
0.357 |
|
2019 |
Panter F, Garcia R, Thewes A, Zaburannyi N, Bunk B, Overmann J, Gutierrez MV, Krug D, Müller R. Production of a dibrominated aromatic secondary metabolite by a planctomycete implies complex interaction with a macroalgal host. Acs Chemical Biology. PMID 31644258 DOI: 10.1021/Acschembio.9B00641 |
0.366 |
|
2019 |
Moeller M, Norris MD, Planke T, Cirnski K, Herrmann J, Müller R, Kirschning A. Scalable Syntheses of Methoxyaspartate and Preparation of the Antibiotic Cystobactamid 861-2 and Highly Potent Derivatives. Organic Letters. PMID 31599597 DOI: 10.1021/Acs.Orglett.9B03143 |
0.507 |
|
2019 |
Gemperlein K, Dietrich D, Kohlstedt M, Zipf G, Bernauer HS, Wittmann C, Wenzel SC, Müller R. Polyunsaturated fatty acid production by Yarrowia lipolytica employing designed myxobacterial PUFA synthases. Nature Communications. 10: 4055. PMID 31492836 DOI: 10.1038/S41467-019-12025-8 |
0.322 |
|
2019 |
Pogorevc D, Panter F, Schillinger C, Jansen R, Wenzel SC, Müller R. Production optimization and biosynthesis revision of corallopyronin A, a potent anti-filarial antibiotic. Metabolic Engineering. 55: 201-211. PMID 31340171 DOI: 10.1016/J.Ymben.2019.07.010 |
0.349 |
|
2019 |
Rebets Y, Nadmid S, Paulus C, Dalem C, Hermann J, Hübner H, Rückert C, Kiemer A, Gmeiner P, Kalinowski J, Müller R, Luzhetskyy A. Perquinolines A-C: Unprecedented Bacterial Tetrahydroisoquinolines Involving an Intriguing Biosynthesis. Angewandte Chemie (International Ed. in English). PMID 31310031 DOI: 10.1002/Anie.201905538 |
0.378 |
|
2019 |
Oueis E, Klefisch T, Zaburannyi N, Garcia R, Plaza A, Müller R. Two Biosynthetic Pathways in Jahnella thaxteri for Thaxteramides, Distinct Types of Lipopeptides. Organic Letters. PMID 31184172 DOI: 10.1021/Acs.Orglett.9B01524 |
0.337 |
|
2019 |
Kiefer A, Bader CD, Held J, Esser A, Rybniker J, Empting M, Müller R, Kazmaier U. Synthesis of New Cyclomarin Derivatives and Their Biological Evaluation towards Mycobacterium Tuberculosis and Plasmodium Falciparum. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 31012978 DOI: 10.1002/Chem.201901640 |
0.337 |
|
2019 |
Banda DH, Perin PM, Brown RJP, Todt D, Solodenko W, Hoffmeyer P, Sahu KK, Houghton M, Meuleman P, Müller R, Kirschning A, Pietschmann T. A central hydrophobic E1 region controls the pH range of hepatitis C virus membrane fusion and susceptibility to fusion inhibitors. Journal of Hepatology. PMID 30769006 DOI: 10.1016/J.Jhep.2019.01.033 |
0.461 |
|
2019 |
Lukežič T, Fayad AA, Bader C, Harmrolfs K, Bartuli J, Groß S, Lešnik U, Hennessen F, Herrmann J, Pikl Š, Petković H, Müller R. Engineering Atypical Tetracycline Formation in Amycolatopsis sulphurea for the Production of Modified Chelocardin Antibiotics. Acs Chemical Biology. PMID 30747520 DOI: 10.1021/Acschembio.8B01125 |
0.332 |
|
2019 |
Planke T, Moreno M, Hüttel S, Fohrer J, Gille F, Norris MD, Siebke M, Wang L, Müller R, Kirschning A. Cystobactamids 920-1 and 920-2: Assignment of the Constitution and Relative Configuration by Total Synthesis. Organic Letters. PMID 30735398 DOI: 10.1021/Acs.Orglett.9B00058 |
0.499 |
|
2019 |
Hauf S, Herrmann J, Miethke M, Gibhardt J, Commichau FM, Müller R, Fuchs S, Halbedel S. Aurantimycin resistance genes contribute to survival of Listeria monocytogenes during life in the environment. Molecular Microbiology. PMID 30648305 DOI: 10.1111/Mmi.14205 |
0.332 |
|
2019 |
Huo L, Hug JJ, Fu C, Bian X, Zhang Y, Müller R. Heterologous expression of bacterial natural product biosynthetic pathways. Natural Product Reports. PMID 30620035 DOI: 10.1039/C8Np00091C |
0.55 |
|
2019 |
Fu C, Xie F, Hoffmann J, Wang Q, Bauer A, Brönstrup M, Mahmud T, Müller R. Front Cover: Armeniaspirol Antibiotic Biosynthesis: Chlorination and Oxidative Dechlorination Steps Affording Spiro[4.4]non‐8‐ene (ChemBioChem 6/2019) Chembiochem. 20: 734-734. DOI: 10.1002/Cbic.201900106 |
0.493 |
|
2018 |
Bruns H, Ziesche L, Taniwal NK, Wolter L, Brinkhoff T, Herrmann J, Müller R, Schulz S. -Acylated amino acid methyl esters from marine group bacteria. Beilstein Journal of Organic Chemistry. 14: 2964-2973. PMID 30591820 DOI: 10.3762/Bjoc.14.276 |
0.491 |
|
2018 |
Fu C, Xie F, Hoffmann J, Wang Q, Bauer A, Brönstrup M, Mahmud T, Müller R. Armeniaspirol antibiotic biosynthesis: Chlorination and oxidative dechlorination steps affording spiro[4.4]non-8-ene formation. Chembiochem : a European Journal of Chemical Biology. PMID 30556942 DOI: 10.1002/Cbic.201800791 |
0.578 |
|
2018 |
Panter F, Krug D, Müller R. Novel methoxymethacrylate natural products uncovered by statistics-based mining of the Myxococcus fulvus secondary metabolome. Acs Chemical Biology. PMID 30543288 DOI: 10.1021/Acschembio.8B00948 |
0.346 |
|
2018 |
Yan F, Müller R. Class I methyltransferase VioH catalyzes unusual SAM cyclization leading to 4-methylazetidinecarboxylic acid formation in vioprolide biosynthesis. Acs Chemical Biology. PMID 30540188 DOI: 10.1021/Acschembio.8B00958 |
0.321 |
|
2018 |
Hug JJ, Panter F, Krug D, Müller R. Genome mining reveals uncommon alkylpyrones as type III PKS products from myxobacteria. Journal of Industrial Microbiology & Biotechnology. PMID 30506464 DOI: 10.1007/S10295-018-2105-6 |
0.348 |
|
2018 |
Sikandar A, Cirnski K, Testolin G, Volz C, Brönstrup M, Kalinina OV, Müller R, Koehnke J. Adaptation of a Bacterial Multidrug Resistance System Revealed by the Structure and Function of AlbA. Journal of the American Chemical Society. PMID 30422653 DOI: 10.2210/Pdb6H96/Pdb |
0.312 |
|
2018 |
Reinartz S, Lieber S, Pesek J, Brandt DT, Asafova A, Finkernagel F, Watzer B, Nockher WA, Nist A, Stiewe T, Jansen JM, Wagner U, Konzer A, Graumann J, Grosse R, et al. Cell-type-selective pathways and clinical associations of lysophosphatidic acid biosynthesis and signaling in the ovarian cancer microenvironment. Molecular Oncology. PMID 30353652 DOI: 10.1002/1878-0261.12396 |
0.305 |
|
2018 |
Yan F, Burgard C, Popoff A, Zaburannyi N, Zipf G, Maier J, Bernauer HS, Wenzel SC, Müller R. Synthetic biology approaches and combinatorial biosynthesis towards heterologous lipopeptide production. Chemical Science. 9: 7510-7519. PMID 30319751 DOI: 10.1039/C8Sc02046A |
0.355 |
|
2018 |
Schulz E, Goes A, Garcia R, Panter F, Koch M, Müller R, Fuhrmann K, Fuhrmann G. Biocompatible bacteria-derived vesicles show inherent antimicrobial activity. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 30292423 DOI: 10.1016/J.Jconrel.2018.09.030 |
0.313 |
|
2018 |
Auerbach D, Yan F, Zhang Y, Müller R. Characterization of an unusual glycerate esterification process in vioprolide biosynthesis. Acs Chemical Biology. PMID 30286293 DOI: 10.1021/Acschembio.8B00826 |
0.335 |
|
2018 |
Gemperlein K, Zaburannyi N, Garcia R, La Clair JJ, Müller R. Metabolic and Biosynthetic Diversity in Marine Myxobacteria. Marine Drugs. 16. PMID 30189599 DOI: 10.3390/Md16090314 |
0.31 |
|
2018 |
Surup F, Chauhan D, Niggemann J, Bartok E, Herrmann J, Keck M, Zander W, Stadler M, Hornung V, Müller R. Activation of the NLRP3 Inflammasome by Hyaboron, a new Asymmetric Boron-Containing Macrodiolide from the Myxobacterium Hyalangium minutum. Acs Chemical Biology. PMID 30183250 DOI: 10.1021/Acschembio.8B00659 |
0.324 |
|
2018 |
Garcia R, La Clair JJ, Müller R. Future Directions of Marine Myxobacterial Natural Product Discovery Inferred from Metagenomics. Marine Drugs. 16. PMID 30158489 DOI: 10.3390/Md16090303 |
0.309 |
|
2018 |
Garcia R, Müller R. Simulacricoccus ruber gen. nov., sp. nov., a microaerotolerant, non-fruiting, myxospore-forming soil myxobacterium and emended description of the family Myxococcaceae. International Journal of Systematic and Evolutionary Microbiology. PMID 30113300 DOI: 10.1099/Ijsem.0.002936 |
0.317 |
|
2018 |
Gorges J, Panter F, Kjaerulff L, Hoffmann T, Kazmaier U, Müller R. Structure, Total Synthesis and Biosynthesis of Chloromyxamides - Myxobacterial Tetrapeptides Featuring an Uncommon 6-Chloromethyl-5-methoxypipecolic Acid Building Block. Angewandte Chemie (International Ed. in English). PMID 30088846 DOI: 10.1002/Anie.201808028 |
0.352 |
|
2018 |
Panter F, Krug D, Baumann S, Müller R. Self-resistance guided genome mining uncovers new topoisomerase inhibitors from myxobacteria. Chemical Science. 9: 4898-4908. PMID 29910943 DOI: 10.1039/C8Sc01325J |
0.341 |
|
2018 |
Hug JJ, Bader CD, Remškar M, Cirnski K, Müller R. Concepts and Methods to Access Novel Antibiotics from Actinomycetes. Antibiotics (Basel, Switzerland). 7. PMID 29789481 DOI: 10.3390/Antibiotics7020044 |
0.346 |
|
2018 |
Witzgall F, Depke T, Hoffmann M, Empting M, Brönstrup M, Müller R, Blankenfeldt W. The Alkylquinolone Repertoire of Pseudomonas aeruginosa is linked to Structural Flexibility of the FabH-like PQS Biosynthesis Enzyme PqsBC. Chembiochem : a European Journal of Chemical Biology. PMID 29722462 DOI: 10.1002/Cbic.201800153 |
0.317 |
|
2018 |
Yan F, Auerbach D, Chai Y, Keller L, Tu Q, Hüttel S, Glemser A, Grab HA, Bach T, Zhang Y, Müller R. Biosynthesis and Heterologous Production of Vioprolides: Rational Biosynthetic Engineering and Unprecedented 4-Methylazetidinecarboxylic Acid Formation. Angewandte Chemie (International Ed. in English). PMID 29694699 DOI: 10.1002/Anie.201802479 |
0.382 |
|
2018 |
Thongkongkaew T, Ding W, Bratovanov E, Oueis E, Garcia-Altares M, Zaburannyi N, Harmrolfs K, Zhang Y, Scherlach K, Müller R, Hertweck C. Two Types of Threonine-Tagged Lipopeptides Synergize in Host Colonization by Pathogenic Burkholderia Species. Acs Chemical Biology. PMID 29669203 DOI: 10.1021/Acschembio.8B00221 |
0.501 |
|
2018 |
Wang X, Zhou H, Chen H, Jing X, Zheng W, Li R, Sun T, Liu J, Fu J, Huo L, Li YZ, Shen Y, Ding X, Müller R, Bian X, et al. Discovery of recombinases enables genome mining of cryptic biosynthetic gene clusters in Burkholderiales species. Proceedings of the National Academy of Sciences of the United States of America. PMID 29666226 DOI: 10.1073/Pnas.1720941115 |
0.526 |
|
2018 |
Santiago M, Lee W, Fayad AA, Coe KA, Rajagopal M, Do T, Hennessen F, Srisuknimit V, Müller R, Meredith TC, Walker S. Genome-wide mutant profiling predicts the mechanism of a Lipid II binding antibiotic. Nature Chemical Biology. PMID 29662210 DOI: 10.1038/S41589-018-0041-4 |
0.311 |
|
2018 |
Hoffmann T, Krug D, Bozkurt N, Duddela S, Jansen R, Garcia R, Gerth K, Steinmetz H, Müller R. Correlating chemical diversity with taxonomic distance for discovery of natural products in myxobacteria. Nature Communications. 9: 803. PMID 29476047 DOI: 10.1038/S41467-018-03184-1 |
0.336 |
|
2018 |
Carrillo Rincón AF, Magdevska V, Kranjc L, Fujs Š, Müller R, Petković H. Production of extracellular heterologous proteins in Streptomyces rimosus, producer of the antibiotic oxytetracycline. Applied Microbiology and Biotechnology. PMID 29417200 DOI: 10.1007/S00253-018-8793-Z |
0.302 |
|
2018 |
von Tesmar A, Hoffmann M, Abou Fayad A, Hüttel S, Schmitt V, Herrmann J, Müller R. Biosynthesis of the Klebsiella oxytoca pathogenicity factor tilivallin: Heterologous expression, in vitro biosynthesis and inhibitor development. Acs Chemical Biology. PMID 29389112 DOI: 10.1021/Acschembio.7B00990 |
0.348 |
|
2018 |
Kappler S, Karmann L, Prudel C, Herrmann J, Caddeu G, Müller R, Vollmar AM, Zahler S, Kazmaier U. Synthesis and Biological Evaluation of Modified Miuraenamides European Journal of Organic Chemistry. 2018: 6952-6965. DOI: 10.1002/Ejoc.201801391 |
0.342 |
|
2017 |
Meng Z, Souillart L, Monks B, Huwyler N, Herrmann J, Müller R, Fürstner A. A "Motif-Oriented" Total Synthesis of Nannocystin Ax. Preparation and Biological Assessment of Analogues. The Journal of Organic Chemistry. PMID 29265814 DOI: 10.1021/Acs.Joc.7B02871 |
0.317 |
|
2017 |
Bruns H, Herrmann J, Müller R, Wang H, Wagner Döbler I, Schulz S. Oxygenated N-Acyl Alanine Methyl Esters (NAMEs) from the Marine Bacterium Roseovarius tolerans EL-164. Journal of Natural Products. PMID 29261310 DOI: 10.1021/Acs.Jnatprod.7B00757 |
0.473 |
|
2017 |
Surup F, Viehrig K, Rachid S, Plaza A, Maurer CK, Hartmann RW, Müller R. Crocadepsins-Depsipeptides from the Myxobacterium Chondromyces crocatus Found by a Genome Mining Approach. Acs Chemical Biology. PMID 29220569 DOI: 10.1021/Acschembio.7B00900 |
0.355 |
|
2017 |
Lukat P, Katsuyama Y, Wenzel S, Binz T, König C, Blankenfeldt W, Brönstrup M, Müller R. Biosynthesis of methyl-proline containing griselimycins, natural products with anti-tuberculosis activity. Chemical Science. 8: 7521-7527. PMID 29163906 DOI: 10.1039/C7Sc02622F |
0.362 |
|
2017 |
Fu C, Sikandar A, Donner J, Zaburannyi N, Herrmann J, Reck M, Wagner-Döbler I, Koehnke J, Müller R. The natural product carolacton inhibits folate-dependent C1 metabolism by targeting FolD/MTHFD. Nature Communications. 8: 1529. PMID 29142318 DOI: 10.1038/S41467-017-01671-5 |
0.329 |
|
2017 |
Sucipto H, Pogorevc D, Luxenburger E, Wenzel SC, Müller R. Heterologous production of myxobacterial α-pyrone antibiotics in Myxococcus xanthus. Metabolic Engineering. 44: 160-170. PMID 29030273 DOI: 10.1016/J.Ymben.2017.10.004 |
0.325 |
|
2017 |
Kjaerulff L, Sikandar A, Zaburannyi N, Adam S, Herrmann J, Koehnke J, Müller R. Thioholgamides - thioamide-containing cytotoxic RiPPs natural products. Acs Chemical Biology. PMID 28981254 DOI: 10.1021/Acschembio.7B00676 |
0.35 |
|
2017 |
Donner J, Reck M, Bunk B, Jarek M, App CB, Meier-Kolthoff JP, Overmann J, Müller R, Kirschning A, Wagner-Döbler I. The Biofilm Inhibitor Carolacton Enters Gram-Negative Cells: Studies Using a TolC-Deficient Strain of Escherichia coli. Msphere. 2. PMID 28959742 DOI: 10.1128/mSphereDirect.00375-17 |
0.47 |
|
2017 |
Gemperlein K, Hoffmann M, Huo L, Pilak P, Petzke L, Müller R, Wenzel SC. Synthetic biology approaches to establish a heterologous production system for coronatines. Metabolic Engineering. PMID 28951265 DOI: 10.1016/J.Ymben.2017.09.009 |
0.571 |
|
2017 |
Kalesse M, Müller R, Witte SNR, Hug JJ, Géraldy M. Biosynthesis, and Total Synthesis of Pyrronazol B a Secondary Metabolite from Nannocystis pusilla. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 28944573 DOI: 10.1002/Chem.201703782 |
0.323 |
|
2017 |
von Tesmar A, Hoffmann M, Pippel J, Fayad AA, Dausend-Werner S, Bauer A, Blankenfeldt W, Müller R. Total Biosynthesis of the Pyrrolo[4,2]benzodiazepine Scaffold Tomaymycin on an In Vitro Reconstituted NRPS System. Cell Chemical Biology. PMID 28890318 DOI: 10.1016/J.Chembiol.2017.08.001 |
0.321 |
|
2017 |
Beckmann A, Hüttel S, Schmitt V, Müller R, Stadler M. Optimization of the biotechnological production of a novel class of anti-MRSA antibiotics from Chitinophaga sancti. Microbial Cell Factories. 16: 143. PMID 28818083 DOI: 10.1186/S12934-017-0756-Z |
0.32 |
|
2017 |
Bihelovic F, Stichnoth D, Müller R, Trauner D, Surup F. A Synthesis of Crocagin A. Angewandte Chemie (International Ed. in English). PMID 28812331 DOI: 10.1002/Anie.201612641 |
0.301 |
|
2017 |
Trauner D, Cheng B, Müller R. Total Syntheses of Cystobactamids and Structural Confirmation of Cystobactamid 919-2. Angewandte Chemie (International Ed. in English). PMID 28731542 DOI: 10.1002/Anie.201705387 |
0.312 |
|
2017 |
Müller R, Hüttel S, Testolin G, Herrmann J, Planke T, Gille F, Moreno M, Stadler M, Brönstrup M, Kirschning A. Discovery and total synthesis of natural cystobactamid derivatives with superior activity against Gram-negative pathogens. Angewandte Chemie (International Ed. in English). PMID 28730677 DOI: 10.1002/Anie.201705913 |
0.53 |
|
2017 |
Kjaerulff L, Raju R, Panter F, Scheid U, Garcia R, Herrmann J, Müller R. Pyxipyrrolones: Novel cytotoxic myxobacterial metabolites. Structure elucidation and biosynthesis proposal. Angewandte Chemie (International Ed. in English). PMID 28590072 DOI: 10.1002/Anie.201704790 |
0.366 |
|
2017 |
Stumpf M, Müller R, Gaßen B, Wehrstedt R, Fey P, Karow MA, Eichinger L, Glöckner G, Noegel AA. A Tripeptidyl peptidase 1 is a binding partner of GPHR (Golgi pH regulator) in Dictyostelium. Disease Models & Mechanisms. PMID 28546289 DOI: 10.1242/Dmm.029280 |
0.315 |
|
2017 |
Viehrig K, Surup F, Volz C, Herrmann J, Abou Fayad A, Adam S, Köhnke J, Trauner D, Müller R. Structure and Biosynthesis of Crocagins: Polycyclic Postranslationally Modified Ribosomal Peptides from Chondromyces crocatus. Angewandte Chemie (International Ed. in English). PMID 28544148 DOI: 10.1002/Anie.201612640 |
0.358 |
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2017 |
Bock T, Luxenburger E, Hoffmann J, Schütza V, Feiler C, Müller R, Blankenfeldt W. AibA/AibB Induces an Intramolecular Decarboxylation in Isovalerate Biosynthesis by Myxococcus xanthus. Angewandte Chemie (International Ed. in English). PMID 28508504 DOI: 10.1002/Anie.201701992 |
0.339 |
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2017 |
Bian X, Tang B, Yu Y, Tu Q, Gross F, Wang H, Li A, Fu J, Shen Y, Li YZ, Stewart AF, Zhao G, Ding X, Müller R, Zhang Y. Heterologous production and yields improvement of epothilones in the Burkholderiales strain DSM 7029. Acs Chemical Biology. PMID 28467833 DOI: 10.1021/Acschembio.7B00097 |
0.355 |
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2017 |
Montes Vidal D, von Rymon-Lipinski AL, Ravella S, Groenhagen U, Herrmann J, Zaburannyi N, Zarbin PH, Varadarajan AR, Ahrens CH, Weisskopf L, Müller R, Schulz S. Long-Chain Alkyl Cyanides: Unprecedented Volatile Compounds Released by Pseudomonas and Micromonospora Bacteria. Angewandte Chemie (International Ed. in English). PMID 28276609 DOI: 10.1002/Anie.201611940 |
0.507 |
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2017 |
Kirschning A, Wang LL, Candito D, Hermann J, Müller R, Dräger G. Harnessing a p-quinone methide intermediate in the biomimetic total synthesis of the highly active antibiotic 20-deoxy-elansolid B1. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 28195370 DOI: 10.1002/Chem.201605884 |
0.516 |
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2017 |
Fu C, Auerbach D, Li Y, Scheid U, Luxenburger E, Garcia R, Irschik H, Müller R. Solving the Puzzle of One-Carbon Loss in Ripostatin Biosynthesis. Angewandte Chemie (International Ed. in English). PMID 28098952 DOI: 10.1002/Anie.201609950 |
0.342 |
|
2017 |
Hüttel S, Testolin G, Herrmann J, Planke T, Gille F, Moreno M, Stadler M, Brönstrup M, Kirschning A, Müller R. Entdeckung und Totalsynthese von natürlichen Cystobactamid-Derivaten mit herausragender Aktivität gegen Gram-negative Pathogene Angewandte Chemie. 129: 12934-12938. DOI: 10.1002/Ange.201705913 |
0.461 |
|
2017 |
Kjaerulff L, Raju R, Panter F, Scheid U, Garcia R, Herrmann J, Müller R. Die Pyxipyrrolone: Strukturaufklärung und Biosynthese zytotoxischer myxobakterieller Sekundärmetabolite Angewandte Chemie. 129: 9743-9747. DOI: 10.1002/Ange.201704790 |
0.364 |
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2017 |
Vidal DM, Rymon‐Lipinski Av, Ravella S, Groenhagen U, Herrmann J, Zaburannyi N, Zarbin PHG, Varadarajan AR, Ahrens CH, Weisskopf L, Müller R, Schulz S. Langkettige Alkylcyanide, beispiellose flüchtige Verbindungen aus Pseudomonas‐ und Micromonospora‐Bakterien Angewandte Chemie. 129: 4406-4410. DOI: 10.1002/Ange.201611940 |
0.385 |
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2016 |
Wu H, Wang Y, Yuan L, Mao Y, Wang W, Zhu L, Wu P, Fu C, Müller R, Weaver DT, Zhang L, Zhang B. Inactivation of SACE_3446, a TetR family transcriptional regulator, stimulates erythromycin production in Saccharopolyspora erythraea. Synthetic and Systems Biotechnology. 1: 39-46. PMID 29062926 DOI: 10.1016/J.Synbio.2016.01.004 |
0.355 |
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2016 |
Chen J, Liu M, Liu X, Miao J, Fu C, Gao H, Müller R, Zhang Q, Zhang L. Interrogation of Streptomyces avermitilis for efficient production of avermectins. Synthetic and Systems Biotechnology. 1: 7-16. PMID 29062922 DOI: 10.1016/J.Synbio.2016.03.002 |
0.319 |
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2016 |
Bock T, Volz C, Hering V, Scrima A, Müller R, Blankenfeldt W. The AibR-isovaleryl coenzyme A regulator and its DNA binding site - a model for the regulation of alternative de novo isovaleryl coenzyme A biosynthesis in Myxococcus xanthus. Nucleic Acids Research. PMID 27940564 DOI: 10.1093/Nar/Gkw1238 |
0.32 |
|
2016 |
Herrmann J, Fayad AA, Müller R. Natural products from myxobacteria: novel metabolites and bioactivities. Natural Product Reports. PMID 27907217 DOI: 10.1039/C6Np00106H |
0.318 |
|
2016 |
Wink J, Moradi A, Ebrahimipour GH, Mohr K, Kämpfer P, Glaeser S, Hennessen F, Gemperlein K, Ram AP, Wolf C, Müller R. Racemicystis persica sp. nov., a novel myxobacterium from Iranian soil. International Journal of Systematic and Evolutionary Microbiology. PMID 27902273 DOI: 10.1099/Ijsem.0.001655 |
0.309 |
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2016 |
Luniak N, Meiser P, Burkart S, Müller R. Heterologous expression of the plant cysteine protease bromelain and its inhibitor in Pichia pastoris. Biotechnology Progress. PMID 27860461 DOI: 10.1002/Btpr.2405 |
0.31 |
|
2016 |
Herrmann J, Lukežič T, Kling A, Baumann S, Hüttel S, Petković H, Müller R. Strategies for the Discovery and Development of New Antibiotics from Natural Products: Three Case Studies. Current Topics in Microbiology and Immunology. PMID 27738913 DOI: 10.1007/82_2016_498 |
0.336 |
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2016 |
Mann G, Huo L, Adam S, Nardone B, Vendome J, Westwood NJ, Müller R, Koehnke J. Structure and substrate recognition of the Bottromycin maturation enzyme BotP. Chembiochem : a European Journal of Chemical Biology. PMID 27653442 DOI: 10.1002/Cbic.201600406 |
0.529 |
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2016 |
Wang M, Carver JJ, Phelan VV, Sanchez LM, Garg N, Peng Y, Nguyen DD, Watrous J, Kapono CA, Luzzatto-Knaan T, Porto C, Bouslimani A, Melnik AV, Meehan MJ, Liu WT, et al. Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking. Nature Biotechnology. 34: 828-837. PMID 27504778 DOI: 10.1038/Nbt.3597 |
0.61 |
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2016 |
Donner J, Reck M, Bergmann S, Kirschning A, Müller R, Wagner-Döbler I. The biofilm inhibitor Carolacton inhibits planktonic growth of virulent pneumococci via a conserved target. Scientific Reports. 6: 29677. PMID 27404808 DOI: 10.1038/Srep29677 |
0.523 |
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2016 |
Steinmetz H, Li J, Fu C, Zaburannyi N, Kunze B, Harmrolfs K, Schmitt V, Herrmann J, Reichenbach H, Höfle G, Kalesse M, Müller R. Isolation, Structure Elucidation, and (Bio)Synthesis of Haprolid, a Cell-Type-Specific Myxobacterial Cytotoxin. Angewandte Chemie (International Ed. in English). PMID 27404448 DOI: 10.1002/Anie.201603288 |
0.375 |
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2016 |
Bock T, Reichelt J, Müller R, Blankenfeldt W. The structure of LiuC, a 3-hydroxy-3-methylglutaconyl CoA dehydratase involved in isovaleryl CoA biosynthesis in Myxococcus xanthus, reveals insights into specificity and catalysis. Chembiochem : a European Journal of Chemical Biology. PMID 27271456 DOI: 10.1002/Cbic.201600225 |
0.327 |
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2016 |
Tautz T, Hoffmann J, Hoffmann T, Steinmetz H, Washausen P, Kunze B, Huch V, Kitsche A, Reichenbach H, Höfle G, Müller R, Kalesse M. Isolation, Structure Elucidation, Biosynthesis, and Synthesis of Antalid, a Secondary Metabolite from Polyangium species. Organic Letters. PMID 27220069 DOI: 10.1021/Acs.Orglett.6B00810 |
0.332 |
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2016 |
Bock T, Kasten J, Müller R, Blankenfeldt W. Crystal structure of the HMG-CoA synthase MvaS from the Gram-negative bacterium Myxococcus xanthus. Chembiochem : a European Journal of Chemical Biology. PMID 27124816 DOI: 10.1002/Cbic.201600070 |
0.342 |
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2016 |
Awal RP, Garcia R, Müller R. Racemicystis crocea gen. nov., sp. nov., a novel soil myxobacterium in Polyangiaceae. International Journal of Systematic and Evolutionary Microbiology. PMID 27046779 DOI: 10.1099/Ijsem.0.001045 |
0.306 |
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2016 |
Lohße A, Kolinko I, Raschdorf O, Uebe R, Borg S, Brachmann A, Plitzko JM, Müller R, Zhang Y, Schüler D. Overproduction of magnetosomes by genomic amplification of biosynthetic gene clusters in a magnetotactic bacterium. Applied and Environmental Microbiology. PMID 26969709 DOI: 10.1128/Aem.03860-15 |
0.322 |
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2016 |
Tu Q, Herrmann J, Hu S, Raju R, Bian X, Zhang Y, Müller R. Genetic engineering and heterologous expression of the disorazol biosynthetic gene cluster via Red/ET recombineering. Scientific Reports. 6: 21066. PMID 26875499 DOI: 10.1038/Srep21066 |
0.359 |
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2016 |
Preisitsch M, Heiden SE, Beerbaum M, Niedermeyer TH, Schneefeld M, Herrmann J, Kumpfmüller J, Thürmer A, Neidhardt I, Wiesner C, Daniel R, Müller R, Bange FC, Schmieder P, Schweder T, et al. Effects of Halide Ions on the Carbamidocyclophane Biosynthesis in Nostoc sp. CAVN2. Marine Drugs. 14: 21. PMID 26805858 DOI: 10.3390/Md14010021 |
0.35 |
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2016 |
Essig S, Schmalzbauer B, Bretzke S, Scherer O, Koeberle A, Werz O, Müller R, Menche D. Predictive Bioinformatic Assignment of Methyl-Bearing Stereocenters, Total Synthesis, and an Additional Molecular Target of Ajudazol B. The Journal of Organic Chemistry. 81: 1333-57. PMID 26796481 DOI: 10.1021/Acs.Joc.5B02844 |
0.35 |
|
2016 |
Zaburannyi N, Bunk B, Maier J, Overmann J, Müller R. Genome Analysis of the Fruiting Body-Forming Myxobacterium Chondromyces crocatus Reveals High Potential for Natural Product Biosynthesis. Applied and Environmental Microbiology. 82: 1945-57. PMID 26773087 DOI: 10.1128/Aem.03011-15 |
0.327 |
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2016 |
Preisitsch M, Niedermeyer TH, Heiden SE, Neidhardt I, Kumpfmüller J, Wurster M, Harmrolfs K, Wiesner C, Enke H, Müller R, Mundt S. Cylindrofridins A-C, Linear Cylindrocyclophane-Related Alkylresorcinols from the Cyanobacterium Cylindrospermum stagnale. Journal of Natural Products. 79: 106-15. PMID 26684177 DOI: 10.1021/Acs.Jnatprod.5B00768 |
0.312 |
|
2016 |
Schulz S, Schmidt W, Jones P, Herrmann J, Müller R. An Unprecedented Octahydro-3H-oxeto[2,3,4-ij]isochromene Ring System Formed by a Trichloromethyl-Anion-Induced Reaction Cascade Synlett. 28: 467-470. DOI: 10.1055/S-0036-1588917 |
0.459 |
|
2015 |
Bian X, Plaza A, Zhang Y, Müller R. Two more pieces of the colibactin genotoxin puzzle from Escherichia coli show incorporation of an unusual 1-aminocyclopropanecarboxylic acid moiety. Chemical Science. 6: 3154-3160. PMID 28706687 DOI: 10.1039/C5Sc00101C |
0.416 |
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2015 |
Garcia R, Stadler M, Gemperlein K, Müller R. Aetherobacter fasciculatus gen. nov., sp. nov. and Aetherobacter rufus gen. nov., sp. nov., two novel myxobacteria with promising biotechnological applications. International Journal of Systematic and Evolutionary Microbiology. PMID 26637815 DOI: 10.1099/Ijsem.0.000813 |
0.32 |
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2015 |
Gemperlein K, Zipf G, Bernauer HS, Müller R, Wenzel SC. Metabolic engineering of Pseudomonas putida for production of docosahexaenoic acid based on a myxobacterial PUFA synthase. Metabolic Engineering. PMID 26617065 DOI: 10.1016/J.Ymben.2015.11.001 |
0.364 |
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2015 |
Wenzel SC, Hoffmann H, Zhang J, Debussche L, Haag-Richter S, Kurz M, Nardi F, Lukat P, Kochems I, Tietgen H, Schummer D, Nicolas JP, Calvet L, Czepczor V, Vrignaud P, et al. Production of the Bengamide Class of Marine Natural Products in Myxobacteria: Biosynthesis and Structure-Activity Relationships. Angewandte Chemie (International Ed. in English). PMID 26514647 DOI: 10.1002/Anie.201508277 |
0.358 |
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2015 |
Yin J, Hoffmann M, Bian X, Tu Q, Yan F, Xia L, Ding X, Stewart AF, Müller R, Fu J, Zhang Y. Direct cloning and heterologous expression of the salinomycin biosynthetic gene cluster from Streptomyces albus DSM41398 in Streptomyces coelicolor A3(2). Scientific Reports. 5: 15081. PMID 26459865 DOI: 10.1038/Srep15081 |
0.354 |
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2015 |
Jungmann K, Jansen R, Gerth K, Huch V, Krug D, Fenical W, Müller R. Two of a Kind-The Biosynthetic Pathways of Chlorotonil and Anthracimycin. Acs Chemical Biology. PMID 26348978 DOI: 10.1021/Acschembio.5B00523 |
0.37 |
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2015 |
Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, de Bruijn I, Chooi YH, Claesen J, Coates RC, Cruz-Morales P, Duddela S, Düsterhus S, Edwards DJ, Fewer DP, et al. Minimum Information about a Biosynthetic Gene cluster. Nature Chemical Biology. 11: 625-31. PMID 26284661 DOI: 10.1038/Nchembio.1890 |
0.767 |
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2015 |
Perin PM, Haid S, Brown RJ, Doerrbecker J, Schulze K, Zeilinger C, von Schaewen M, Heller B, Vercauteren K, Luxenburger E, Baktash YM, Vondran FW, Speerstra S, Awadh A, Mukhtarov F, et al. Flunarizine prevents hepatitis C virus membrane fusion in a genotype-dependent manner by targeting the potential fusion peptide within E1. Hepatology (Baltimore, Md.). PMID 26248546 DOI: 10.1002/Hep.28111 |
0.466 |
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2015 |
Nadmid S, Plaza A, Garcia R, Müller R. Cystochromones, Unusual Chromone-Containing Polyketides from the Myxobacterium Cystobacter sp. MCy9104. Journal of Natural Products. 78: 2023-8. PMID 26214047 DOI: 10.1021/Acs.Jnatprod.5B00343 |
0.313 |
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2015 |
Mohr KI, Volz C, Jansen R, Wray V, Hoffmann J, Bernecker S, Wink J, Gerth K, Stadler M, Müller R. Pinensins: The First Antifungal Lantibiotics. Angewandte Chemie (International Ed. in English). PMID 26211520 DOI: 10.1002/Anie.201500927 |
0.365 |
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2015 |
Kemmerer M, Finkernagel F, Cavalcante MF, Abdalla DS, Müller R, Brüne B, Namgaladze D. AMP-Activated Protein Kinase Interacts with the Peroxisome Proliferator-Activated Receptor Delta to Induce Genes Affecting Fatty Acid Oxidation in Human Macrophages. Plos One. 10: e0130893. PMID 26098914 DOI: 10.1371/Journal.Pone.0130893 |
0.323 |
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2015 |
Keller L, Plaza A, Dubiella C, Groll M, Kaiser M, Müller R. Macyranones: Structure, Biosynthesis, and Binding Mode of an Unprecedented Epoxyketone that Targets the 20S Proteasome. Journal of the American Chemical Society. 137: 8121-30. PMID 26050527 DOI: 10.1021/Jacs.5B03833 |
0.332 |
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2015 |
Fu C, Keller L, Bauer A, Brönstrup M, Froidbise A, Hammann P, Herrmann J, Mondesert G, Kurz M, Schiell M, Schummer D, Toti L, Wink J, Müller R. Biosynthetic Studies of Telomycin Reveal New Lipopeptides with Enhanced Activity. Journal of the American Chemical Society. 137: 7692-705. PMID 26043159 DOI: 10.1021/Jacs.5B01794 |
0.393 |
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2015 |
Weber T, Blin K, Duddela S, Krug D, Kim HU, Bruccoleri R, Lee SY, Fischbach MA, Müller R, Wohlleben W, Breitling R, Takano E, Medema MH. antiSMASH 3.0-a comprehensive resource for the genome mining of biosynthetic gene clusters. Nucleic Acids Research. 43: W237-43. PMID 25948579 DOI: 10.1093/Nar/Gkv437 |
0.334 |
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2015 |
Sahner JH, Sucipto H, Wenzel SC, Groh M, Hartmann RW, Müller R. Advanced mutasynthesis studies on the natural α-pyrone antibiotic myxopyronin from Myxococcus fulvus. Chembiochem : a European Journal of Chemical Biology. 16: 946-53. PMID 25757034 DOI: 10.1002/Cbic.201402666 |
0.301 |
|
2015 |
Bian X, Plaza A, Yan F, Zhang Y, Müller R. Rational and efficient site-directed mutagenesis of adenylation domain alters relative yields of luminmide derivatives in vivo. Biotechnology and Bioengineering. 112: 1343-53. PMID 25683597 DOI: 10.1002/Bit.25560 |
0.34 |
|
2015 |
Franke J, Bock M, Dehn R, Fohrer J, Mhaske SB, Migliorini A, Kanakis AA, Jansen R, Herrmann J, Müller R, Kirschning A. Total and semi-syntheses of antimicrobial thuggacin derivatives. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 4272-84. PMID 25652819 DOI: 10.1002/Chem.201405874 |
0.504 |
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2015 |
Lešnik U, Lukeži? T, Podgoršek A, Horvat J, Polak T, Šala M, Jenko B, Harmrolfs K, Ocampo-Sosa A, Martínez-Martínez L, Herron PR, Fujs Š, Kosec G, Hunter IS, Müller R, et al. Construction of a new class of tetracycline lead structures with potent antibacterial activity through biosynthetic engineering. Angewandte Chemie (International Ed. in English). 54: 3937-40. PMID 25650563 DOI: 10.1002/Anie.201411028 |
0.308 |
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2015 |
Yin J, Zhu H, Xia L, Ding X, Hoffmann T, Hoffmann M, Bian X, Müller R, Fu J, Stewart AF, Zhang Y. A new recombineering system for Photorhabdus and Xenorhabdus. Nucleic Acids Research. 43: e36. PMID 25539914 DOI: 10.1093/Nar/Gku1336 |
0.326 |
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2015 |
Tang Y, Frewert S, Harmrolfs K, Herrmann J, Karmann L, Kazmaier U, Xia L, Zhang Y, Müller R. Heterologous expression of an orphan NRPS gene cluster from Paenibacillus larvae in Escherichia coli revealed production of sevadicin. Journal of Biotechnology. 194: 112-4. PMID 25529345 DOI: 10.1016/J.Jbiotec.2014.12.008 |
0.37 |
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2015 |
Sood S, Awal RP, Wink J, Mohr KI, Rohde M, Stadler M, Kämpfer P, Glaeser SP, Schumann P, Garcia R, Müller R. Aggregicoccus edonensis gen. nov., sp. nov., an unusually aggregating myxobacterium isolated from a soil sample. International Journal of Systematic and Evolutionary Microbiology. 65: 745-53. PMID 24591423 DOI: 10.1099/Ijs.0.061176-0 |
0.303 |
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2015 |
Moreno M, Elgaher WAM, Herrmann J, Schläger N, Hamed MM, Baumann S, Müller R, Hartmann RW, Kirschning A. Synthesis and biological evaluation of cystobactamid 507: A bacterial topoisomerase inhibitor from Cystobacter sp. Synlett. 26: 1175-1178. DOI: 10.1055/S-0034-1380509 |
0.538 |
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2015 |
Sucipto H, Sahner JH, Prusov E, Wenzel SC, Hartmann RW, Koehnke J, Müller R. In vitro reconstitution of α-pyrone ring formation in myxopyronin biosynthesis Chemical Science. 6: 5076-5085. DOI: 10.1039/C5Sc01013F |
0.335 |
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2015 |
Perin P, Haid S, Brown R, Schulze K, Colpitts C, Zeilinger C, von Schaewen M, Heller B, Vercauteren K, Luxenburger E, Andonyadis Y, Vondran F, Kirschning A, Schang L, Müller R, et al. P0674 : Clinically approved T-type calcium channel inhibitors prevent hepatitis C virus (HCV) membrane fusion in a genotype-dependent manner Journal of Hepatology. 62: S574-S575. DOI: 10.1016/S0168-8278(15)30878-3 |
0.442 |
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2015 |
Franke J, Bock M, Dehn R, Fohrer J, Mhaske SB, Migliorini A, Kanakis AA, Jansen R, Herrmann J, Müller R, Kirschning A. Frontispiece: Total and Semi-Syntheses of Antimicrobial Thuggacin Derivatives Chemistry - a European Journal. 21: n/a-n/a. DOI: 10.1002/Chem.201581162 |
0.498 |
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2014 |
Baumann S, Herrmann J, Raju R, Steinmetz H, Mohr KI, Hüttel S, Harmrolfs K, Stadler M, Müller R. Cystobactamids: myxobacterial topoisomerase inhibitors exhibiting potent antibacterial activity. Angewandte Chemie (International Ed. in English). 53: 14605-9. PMID 25510965 DOI: 10.1002/Anie.201409964 |
0.344 |
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2014 |
Jansen R, Sood S, Mohr KI, Kunze B, Irschik H, Stadler M, Müller R. Nannozinones and sorazinones, unprecedented pyrazinones from myxobacteria. Journal of Natural Products. 77: 2545-52. PMID 25397992 DOI: 10.1021/Np500632C |
0.301 |
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2014 |
Surup F, Viehrig K, Mohr KI, Herrmann J, Jansen R, Müller R. Disciformycins A and B: 12-membered macrolide glycoside antibiotics from the myxobacterium Pyxidicoccus fallax active against multiresistant staphylococci. Angewandte Chemie (International Ed. in English). 53: 13588-91. PMID 25294799 DOI: 10.1002/Anie.201406973 |
0.331 |
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2014 |
Fruth M, Plaza A, Hinsberger S, Sahner JH, Haupenthal J, Bischoff M, Jansen R, Müller R, Hartmann RW. Binding mode characterization of novel RNA polymerase inhibitors using a combined biochemical and NMR approach. Acs Chemical Biology. 9: 2656-63. PMID 25207839 DOI: 10.1021/Cb5005433 |
0.321 |
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2014 |
Bian X, Huang F, Wang H, Klefisch T, Müller R, Zhang Y. Heterologous production of glidobactins/luminmycins in Escherichia coli Nissle containing the glidobactin biosynthetic gene cluster from Burkholderia DSM7029. Chembiochem : a European Journal of Chemical Biology. 15: 2221-4. PMID 25147087 DOI: 10.1002/Cbic.201402199 |
0.354 |
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2014 |
Oßwald C, Zaburannyi N, Burgard C, Hoffmann T, Wenzel SC, Müller R. A highly unusual polyketide synthase directs dawenol polyene biosynthesis in Stigmatella aurantiaca. Journal of Biotechnology. 191: 54-63. PMID 25102237 DOI: 10.1016/J.Jbiotec.2014.07.447 |
0.366 |
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2014 |
Sood S, Steinmetz H, Beims H, Mohr KI, Stadler M, Djukic M, von der Ohe W, Steinert M, Daniel R, Müller R. Paenilarvins: Iturin family lipopeptides from the honey bee pathogen Paenibacillus larvae. Chembiochem : a European Journal of Chemical Biology. 15: 1947-55. PMID 25069424 DOI: 10.1002/Cbic.201402139 |
0.319 |
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2014 |
Beck P, Heinemeyer W, Späth AL, Elnakady Y, Müller R, Groll M. Interactions of the natural product kendomycin and the 20S proteasome. Journal of Molecular Biology. 426: 3108-17. PMID 25038530 DOI: 10.1016/J.Jmb.2014.06.019 |
0.319 |
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2014 |
Müller S, Rachid S, Hoffmann T, Surup F, Volz C, Zaburannyi N, Müller R. Biosynthesis of crocacin involves an unusual hydrolytic release domain showing similarity to condensation domains. Chemistry & Biology. 21: 855-65. PMID 24981773 DOI: 10.1016/J.Chembiol.2014.05.012 |
0.334 |
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2014 |
Krug D, Müller R. Secondary metabolomics: the impact of mass spectrometry-based approaches on the discovery and characterization of microbial natural products. Natural Product Reports. 31: 768-83. PMID 24763662 DOI: 10.1039/C3Np70127A |
0.331 |
|
2014 |
Jansen R, Mohr KI, Bernecker S, Stadler M, Müller R. Indothiazinone, an indolyl thiazolyl ketone from a novel myxobacterium belonging to the Sorangiineae. Journal of Natural Products. 77: 1054-60. PMID 24697522 DOI: 10.1021/Np500144T |
0.34 |
|
2014 |
Jansen R, Sood S, Huch V, Kunze B, Stadler M, Müller R. Pyrronazols, metabolites from the myxobacteria Nannocystis pusilla and N. exedens, are unusual chlorinated pyrone-oxazole-pyrroles. Journal of Natural Products. 77: 320-6. PMID 24460410 DOI: 10.1021/Np400877R |
0.304 |
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2014 |
Müller R, Wink J. Future potential for anti-infectives from bacteria - how to exploit biodiversity and genomic potential. International Journal of Medical Microbiology. 304: 3-13. PMID 24119567 DOI: 10.1016/J.Ijmm.2013.09.004 |
0.305 |
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2014 |
Osswald C, Zipf G, Schmidt G, Maier J, Bernauer HS, Müller R, Wenzel SC. Modular construction of a functional artificial epothilone polyketide pathway. Acs Synthetic Biology. 3: 759-72. PMID 23654254 DOI: 10.1021/Sb300080T |
0.332 |
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2014 |
Gemperlein K, Rachid S, Garcia RO, Wenzel SC, Müller R. Polyunsaturated fatty acid biosynthesis in myxobacteria: different PUFA synthases and their product diversity Chemical Science. 5: 1733-1741. DOI: 10.1039/C3Sc53163E |
0.344 |
|
2013 |
Young J, Stevens DC, Carmichael R, Tan J, Rachid S, Boddy CN, Müller R, Taylor RE. Elucidation of gephyronic acid biosynthetic pathway revealed unexpected SAM-dependent methylations. Journal of Natural Products. 76: 2269-76. PMID 24298873 DOI: 10.1021/Np400629V |
0.344 |
|
2013 |
Viehrig K, Surup F, Harmrolfs K, Jansen R, Kunze B, Müller R. Concerted action of P450 plus helper protein to form the amino-hydroxy-piperidone moiety of the potent protease inhibitor crocapeptin. Journal of the American Chemical Society. 135: 16885-94. PMID 24171398 DOI: 10.1021/Ja4047153 |
0.374 |
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2013 |
Storz MP, Brengel C, Weidel E, Hoffmann M, Hollemeyer K, Steinbach A, Müller R, Empting M, Hartmann RW. Biochemical and biophysical analysis of a chiral PqsD inhibitor revealing tight-binding behavior and enantiomers with contrary thermodynamic signatures. Acs Chemical Biology. 8: 2794-2801. PMID 24099650 DOI: 10.1021/Cb400530D |
0.303 |
|
2013 |
Sucipto H, Wenzel SC, Müller R. Exploring chemical diversity of α-pyrone antibiotics: molecular basis of myxopyronin biosynthesis. Chembiochem : a European Journal of Chemical Biology. 14: 1581-9. PMID 23983106 DOI: 10.1002/Cbic.201300289 |
0.332 |
|
2013 |
Li XW, Herrmann J, Zang Y, Grellier P, Prado S, Müller R, Nay B. Synthesis and biological activities of the respiratory chain inhibitor aurachin D and new ring versus chain analogues. Beilstein Journal of Organic Chemistry. 9: 1551-8. PMID 23946854 DOI: 10.3762/Bjoc.9.176 |
0.31 |
|
2013 |
Weidel E, de Jong JC, Brengel C, Storz MP, Braunshausen A, Negri M, Plaza A, Steinbach A, Müller R, Hartmann RW. Structure optimization of 2-benzamidobenzoic acids as PqsD inhibitors for Pseudomonas aeruginosa infections and elucidation of binding mode by SPR, STD NMR, and molecular docking. Journal of Medicinal Chemistry. 56: 6146-55. PMID 23834469 DOI: 10.1021/Jm4006302 |
0.326 |
|
2013 |
Ongley SE, Bian X, Neilan BA, Müller R. Recent advances in the heterologous expression of microbial natural product biosynthetic pathways. Natural Product Reports. 30: 1121-1138. PMID 23832108 DOI: 10.1039/C3Np70034H |
0.349 |
|
2013 |
Ongley SE, Bian X, Zhang Y, Chau R, Gerwick WH, Müller R, Neilan BA. High-titer heterologous production in E. coli of lyngbyatoxin, a protein kinase C activator from an uncultured marine cyanobacterium. Acs Chemical Biology. 8: 1888-93. PMID 23751865 DOI: 10.1021/Cb400189J |
0.332 |
|
2013 |
Streubel G, Bouchard C, Berberich H, Zeller MS, Teichmann S, Adamkiewicz J, Müller R, Klempnauer KH, Bauer UM. PRMT4 is a novel coactivator of c-Myb-dependent transcription in haematopoietic cell lines. Plos Genetics. 9: e1003343. PMID 23505388 DOI: 10.1371/Journal.Pgen.1003343 |
0.312 |
|
2013 |
Adhikary T, Brandt DT, Kaddatz K, Stockert J, Naruhn S, Meissner W, Finkernagel F, Obert J, Lieber S, Scharfe M, Jarek M, Toth PM, Scheer F, Diederich WE, Reinartz S, et al. Inverse PPARβ/δ agonists suppress oncogenic signaling to the ANGPTL4 gene and inhibit cancer cell invasion. Oncogene. 32: 5241-52. PMID 23208498 DOI: 10.1038/Onc.2012.549 |
0.301 |
|
2013 |
Arnison PG, Bibb MJ, Bierbaum G, Bowers AA, Bugni TS, Bulaj G, Camarero JA, Campopiano DJ, Challis GL, Clardy J, Cotter PD, Craik DJ, Dawson M, Dittmann E, Donadio S, et al. Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature. Natural Product Reports. 30: 108-60. PMID 23165928 DOI: 10.1039/C2Np20085F |
0.768 |
|
2013 |
Arnison PG, Bibb MJ, Bierbaum G, Bowers AA, Bugni TS, Bulaj G, Camarero JA, Campopiano DJ, Challis GL, Clardy J, Cotter PD, Craik DJ, Dawson M, Dittmann E, Donadio S, et al. Erratum: Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature (Natural Product Reports (2013) 30 (108-160) DOI:10.1039/C2NP20085F) Natural Product Reports. 30: 1568-1568. DOI: 10.1039/C3Np90040A |
0.733 |
|
2013 |
Raju R, Gromyko O, Fedorenko V, Herrmann J, Luzhetskyy A, Müller R. Rubimycinone A, a new anthraquinone from a terrestrial Streptomyces sp. Tetrahedron Letters. 54: 900-902. DOI: 10.1016/J.Tetlet.2012.11.130 |
0.3 |
|
2012 |
Volz C, Kegler C, Müller R. Enhancer Binding Proteins Act as Hetero-oligomers and Link Secondary Metabolite Production to Myxococcal Development, Motility, and Predation Chemistry & Biology. 19: 1447-1459. PMID 23177199 DOI: 10.1016/J.Chembiol.2012.09.010 |
0.35 |
|
2012 |
Barbie P, Huo L, Müller R, Kazmaier U. Stereoselective synthesis of deuterium-labeled (2S)-cyclohexenyl alanines, biosynthetic intermediates of cinnabaramide. Organic Letters. 14: 6064-7. PMID 23163839 DOI: 10.1021/Ol3029548 |
0.492 |
|
2012 |
Essig S, Bretzke S, Müller R, Menche D. Full stereochemical determination of ajudazols A and B by bioinformatics gene cluster analysis and total synthesis of ajudazol B by an asymmetric ortholithiation strategy. Journal of the American Chemical Society. 134: 19362-5. PMID 23127125 DOI: 10.1021/Ja309685N |
0.307 |
|
2012 |
Steinmetz H, Mohr KI, Zander W, Jansen R, Gerth K, Müller R. Indiacens A and B: prenyl indoles from the myxobacterium Sandaracinus amylolyticus. Journal of Natural Products. 75: 1803-5. PMID 23035772 DOI: 10.1021/Np300288B |
0.326 |
|
2012 |
Huo L, Rachid S, Stadler M, Wenzel SC, Müller R. Synthetic biotechnology to study and engineer ribosomal bottromycin biosynthesis. Chemistry & Biology. 19: 1278-87. PMID 23021914 DOI: 10.1016/J.Chembiol.2012.08.013 |
0.562 |
|
2012 |
Bian X, Plaza A, Zhang Y, Müller R. Luminmycins A-C, cryptic natural products from Photorhabdus luminescens identified by heterologous expression in Escherichia coli. Journal of Natural Products. 75: 1652-1655. PMID 22909174 DOI: 10.1021/Np300444E |
0.339 |
|
2012 |
Bian X, Huang F, Stewart FA, Xia L, Zhang Y, Müller R. Direct Cloning, Genetic Engineering, and Heterologous Expression of the Syringolin Biosynthetic Gene Cluster in E. coli through Red/ET Recombineering Chembiochem. 13: 1946-1952. PMID 22851214 DOI: 10.1002/Cbic.201200310 |
0.349 |
|
2012 |
Steinmetz H, Zander W, Shushni MAM, Jansen R, Gerth K, Dehn R, Dräger G, Kirschning A, Müller R. Precursor-Directed Syntheses and Biological Evaluation of New Elansolid Derivatives Chembiochem. 13: 1813-1817. PMID 22807264 DOI: 10.1002/Cbic.201200228 |
0.535 |
|
2012 |
Zander W, Irschik H, Augustiniak H, Herrmann M, Jansen R, Steinmetz H, Gerth K, Kessler W, Kalesse M, Höfle G, Müller R. Sulfangolids, macrolide sulfate esters from Sorangium cellulosum Chemistry - a European Journal. 18: 6264-6271. PMID 22488821 DOI: 10.1002/Chem.201100851 |
0.321 |
|
2012 |
Chai Y, Shan S, Weissman KJ, Hu S, Zhang Y, Müller R. Heterologous expression and genetic engineering of the tubulysin biosynthetic gene cluster using Red/ET recombineering and inactivation mutagenesis. Chemistry & Biology. 19: 361-71. PMID 22444591 DOI: 10.1016/J.Chembiol.2012.01.007 |
0.329 |
|
2012 |
Pistorius D, Müller R. Discovery of the rhizopodin biosynthetic gene cluster in Stigmatella aurantiaca Sg a15 by genome mining. Chembiochem. 13: 416-426. PMID 22278953 DOI: 10.1002/Cbic.201100575 |
0.354 |
|
2012 |
Xiao Y, Gerth K, Müller R, Wall D. Myxobacterium-produced antibiotic TA (myxovirescin) inhibits type II signal peptidase. Antimicrobial Agents and Chemotherapy. 56: 2014-21. PMID 22232277 DOI: 10.1128/Aac.06148-11 |
0.354 |
|
2012 |
Quade N, Huo L, Rachid S, Heinz DW, Müller R. Unusual carbon fixation gives rise to diverse polyketide extender units. Nature Chemical Biology. 8: 117-24. PMID 22138621 DOI: 10.1038/Nchembio.734 |
0.544 |
|
2012 |
Mohr KI, Garcia RO, Gerth K, Irschik H, Müller R. Sandaracinus amylolyticus gen. nov., sp. nov., a starch-degrading soil myxobacterium, and description of Sandaracinaceae fam. nov. International Journal of Systematic and Evolutionary Microbiology. 62: 1191-8. PMID 21742821 DOI: 10.1099/Ijs.0.033696-0 |
0.302 |
|
2012 |
Raju R, Gromyko O, Fedorenko V, Luzhetskyy A, Müller R. Leopolic acid A, isolated from a terrestrial actinomycete, Streptomyces sp. Tetrahedron Letters. 53: 6300-6301. DOI: 10.1016/J.Tetlet.2012.09.046 |
0.303 |
|
2011 |
Pistorius D, Li Y, Sandmann A, Müller R. Completing the puzzle of aurachin biosynthesis in Stigmatella aurantiaca Sg a15. Molecular Biosystems. 7: 3308-15. PMID 21979787 DOI: 10.1039/C1Mb05328K |
0.332 |
|
2011 |
Pistorius D, Li Y, Mann S, Müller R. Unprecedented anthranilate priming involving two enzymes of the acyl adenylating superfamily in aurachin biosynthesis. Journal of the American Chemical Society. 133: 12362-12365. PMID 21770425 DOI: 10.1021/Ja203653W |
0.362 |
|
2011 |
Stec E, Pistorius D, Müller R, Li S. AuaA, a Membrane‐Bound Farnesyltransferase from Stigmatella aurantiaca, Catalyzes the Prenylation of 2‐Methyl‐4‐hydroxyquinoline in the Biosynthesis of Aurachins Chembiochem. 12: 1724-1730. PMID 21671333 DOI: 10.1002/Cbic.201100188 |
0.366 |
|
2011 |
Cortina NS, Revermann O, Krug D, Müller R. Identification and Characterization of the Althiomycin Biosynthetic Gene Cluster in Myxococcus xanthus DK897 Chembiochem. 12: 1411-1416. PMID 21626639 DOI: 10.1002/Cbic.201100154 |
0.321 |
|
2011 |
Jansen R, Gerth K, Steinmetz H, Reinecke S, Kessler W, Kirschning A, Müller R. Elansolid A3, a unique p-quinone methide antibiotic from Chitinophaga sancti. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 7739-44. PMID 21626585 DOI: 10.1002/Chem.201100457 |
0.446 |
|
2011 |
Zander W, Gerth K, Mohr KI, Kessler W, Jansen R, Müller R. Roimatacene: an antibiotic against Gram-negative bacteria isolated from Cystobacter ferrugineus Cb G35 (Myxobacteria). Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 7875-81. PMID 21618624 DOI: 10.1002/Chem.201003677 |
0.323 |
|
2011 |
Dehn R, Katsuyama Y, Weber A, Gerth K, Jansen R, Steinmetz H, Höfle G, Müller R, Kirschning A. Molecular basis of elansolid biosynthesis: Evidence for an unprecedented quinone methide initiated intramolecular diels-alder cycloaddition/ macrolactonization Angewandte Chemie - International Edition. 50: 3882-3887. PMID 21472917 DOI: 10.1002/Anie.201006880 |
0.48 |
|
2011 |
Kopp M, Irschik H, Gemperlein K, Buntin K, Meiser P, Weissman KJ, Bode HB, Müller R. Insights into the complex biosynthesis of the leupyrrins in Sorangium cellulosum So ce690. Molecular Biosystems. 7: 1549-63. PMID 21365089 DOI: 10.1039/C0Mb00240B |
0.396 |
|
2011 |
Garcia R, Pistorius D, Stadler M, Müller R. Fatty acid-related phylogeny of myxobacteria as an approach to discover polyunsaturated omega-3/6 Fatty acids. Journal of Bacteriology. 193: 1930-42. PMID 21317327 DOI: 10.1128/Jb.01091-10 |
0.309 |
|
2011 |
Adhikary T, Kaddatz K, Finkernagel F, Schönbauer A, Meissner W, Scharfe M, Jarek M, Blöcker H, Müller-Brüsselbach S, Müller R. Genomewide Analyses Define Different Modes of Transcriptional Regulation by Peroxisome Proliferator-Activated Receptor-β/δ (PPARβ/δ) Plos One. 6. PMID 21283829 DOI: 10.1371/Journal.Pone.0016344 |
0.302 |
|
2011 |
Steinmetz H, Gerth K, Jansen R, Dehn R, Reinecke S, Kirschning A, Müller R. Elansolid A, a Unique Macrolide Antibiotic from Chitinophaga sancti Isolated as Two Stable Atropisomers Angewandte Chemie - International Edition. 50: 532-536. PMID 21154488 DOI: 10.1002/Anie.201005226 |
0.481 |
|
2011 |
Nawrath T, Gerth K, Müller R, Schulz S. Volatile methyl esters of medium chain length from the bacterium Chitinophaga Fx7914. Chemistry & Biodiversity. 7: 2228-53. PMID 20860026 DOI: 10.1002/Cbdv.201000190 |
0.444 |
|
2011 |
Stockert J, Adhikary T, Kaddatz K, Finkernagel F, Meissner W, Müller-Brüsselbach S, Müller R. Reverse crosstalk of TGFβ and PPARβ/δ signaling identified by transcriptional profiling Nucleic Acids Research. 39: 119-131. PMID 20846954 DOI: 10.1093/Nar/Gkq773 |
0.317 |
|
2011 |
Nawrath T, Gerth K, Müller R, Schulz S. The biosynthesis of the aroma volatile 2-methyltetrahydrothiophen-3-one in the bacterium Chitinophaga Fx7914. Chembiochem : a European Journal of Chemical Biology. 11: 1914-9. PMID 20680979 DOI: 10.1002/Cbic.201000296 |
0.469 |
|
2011 |
Burkhart JL, Müller R, Kazmaier U. Syntheses and Evaluation of Simplified Pretubulysin Analogues European Journal of Organic Chemistry. 2011: 3050-3059. DOI: 10.1002/Ejoc.201100155 |
0.304 |
|
2011 |
Jansen R, Gerth K, Steinmetz H, Reinecke S, Kessler W, Kirschning A, Müller R. Elansolid A3, a unique p-quinone methide antibiotic from Chitinophaga sancti Chemistry - a European Journal. 17: 7739-7744. DOI: 10.1002/chem.201100457 |
0.375 |
|
2011 |
Barbier J, Jansen R, Irschik H, Benson S, Gerth K, Böhlendorf B, Höfle G, Reichenbach H, Wegner J, Zeilinger C, Kirschning A, Müller R. Isolierung und Totalsynthese der Icumazole und Noricumazole - antimykotische Antibiotika und Kationenkanalblocker aus Sorangium cellulosum Angewandte Chemie. 124: 1282-1286. DOI: 10.1002/Ange.201106435 |
0.44 |
|
2011 |
Dehn R, Katsuyama Y, Weber A, Gerth K, Jansen R, Steinmetz H, Höfle G, Müller R, Kirschning A. Molekulare Grundlage für die Biosynthese von Elansolid: Beweise für eine einzigartige, durch ein Chinonmethid initiierte intramolekulare Diels-Alder-Cycloaddition/Makrolactonisierung Angewandte Chemie. 123: 3968-3973. DOI: 10.1002/Ange.201006880 |
0.452 |
|
2011 |
Steinmetz H, Gerth K, Jansen R, Schläger N, Dehn R, Reinecke S, Kirschning A, Müller R. Elansolid A, ein einzigartiges Antibiotikum aus Chitinophaga sancti: isoliert in Form von zwei stabilen Atropisomeren† Angewandte Chemie. 123: 553-557. DOI: 10.1002/Ange.201005226 |
0.451 |
|
2010 |
Irschik H, Kopp M, Weissman KJ, Buntin K, Piel J, Müller R. Analysis of the sorangicin gene cluster reinforces the utility of a combined phylogenetic/retrobiosynthetic analysis for deciphering natural product assembly by trans-AT PKS Chembiochem. 11: 1840-1849. PMID 20715267 DOI: 10.1002/Cbic.201000313 |
0.546 |
|
2010 |
Daum M, Schnell HJ, Herrmann S, Günther A, Murillo R, Müller R, Bisel P, Müller M, Bechthold A. Functions of genes and enzymes involved in phenalinolactone biosynthesis. Chembiochem : a European Journal of Chemical Biology. 11: 1383-91. PMID 20540056 DOI: 10.1002/Cbic.201000117 |
0.344 |
|
2010 |
Erol O, Schäberle TF, Schmitz A, Rachid S, Gurgui C, El Omari M, Lohr F, Kehraus S, Piel J, Müller R, Königd GM. Biosynthesis of the myxobacterial antibiotic corallopyronin A Chembiochem. 11: 1253-1265. PMID 20503218 DOI: 10.1002/Cbic.201000085 |
0.572 |
|
2010 |
Buntin K, Weissman KJ, Müller R. An unusual thioesterase promotes isochromanone ring formation in ajudazol biosynthesis. Chembiochem. 11: 1137-1146. PMID 20432424 DOI: 10.1002/Cbic.200900712 |
0.321 |
|
2010 |
Buntin K, Irschik H, Weissman KJ, Luxenburger E, Blöcker H, Müller R. Biosynthesis of Thuggacins in Myxobacteria: Comparative Cluster Analysis Reveals Basis for Natural Product Structural Diversity Chemistry & Biology. 17: 342-356. PMID 20416506 DOI: 10.1016/J.Chembiol.2010.02.013 |
0.375 |
|
2010 |
Chai Y, Pistorius D, Ullrich A, Weissman KJ, Kazmaier U, Müller R. Discovery of 23 natural tubulysins from Angiococcus disciformis An d48 and Cystobacter SBCb004. Chemistry & Biology. 17: 296-309. PMID 20338521 DOI: 10.1016/J.Chembiol.2010.01.016 |
0.344 |
|
2010 |
Rachid S, Revermann O, Dauth C, Kazmaier U, Müller R. Characterization of a novel type of oxidative decarboxylase involved in the biosynthesis of the styryl moiety of chondrochloren from an acylated tyrosine. The Journal of Biological Chemistry. 285: 12482-9. PMID 20080978 DOI: 10.1074/Jbc.M109.079707 |
0.371 |
|
2010 |
Naruhn S, Meissner W, Adhikary T, Kaddatz K, Klein T, Watzer B, Müller-Brüsselbach S, Müller R. 15-Hydroxyeicosatetraenoic Acid Is a Preferential Peroxisome Proliferator-Activated Receptor β/δ Agonist Molecular Pharmacology. 77: 171-184. PMID 19903832 DOI: 10.1124/Mol.109.060541 |
0.314 |
|
2010 |
Brodmann T, Janssen D, Sasse F, Irschik H, Jansen R, Müller R, Kalesse M. Isolation and synthesis of chivotriene, a chivosazole shunt product from Sorangium cellulosum European Journal of Organic Chemistry. 5155-5159. DOI: 10.1002/Ejoc.201000781 |
0.345 |
|
2010 |
Jansen R, Irschik H, Huch V, Schummer D, Steinmetz H, Bock M, Schmidt T, Kirschning A, Müller R. Carolacton - A macrolide ketocarbonic acid that reduces biofilm formation by the caries- and endocarditis-associated bacterium Streptococcus mutans European Journal of Organic Chemistry. 1284-1289. DOI: 10.1002/Ejoc.200901126 |
0.514 |
|
2009 |
Nagano T, Pospísil J, Chollet G, Schulthoff S, Hickmann V, Moulin E, Herrmann J, Müller R, Fürstner A. Total synthesis and biological evaluation of the cytotoxic resin glycosides ipomoeassin A-F and analogues. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 9697-706. PMID 19697385 DOI: 10.1002/Chem.200901449 |
0.321 |
|
2009 |
Li Y, Müller R. Non-modular polyketide synthases in myxobacteria. Phytochemistry. 70: 1850-1857. PMID 19586645 DOI: 10.1016/J.Phytochem.2009.05.003 |
0.302 |
|
2009 |
Wenzel SC, Müller R. Myxobacteria—‘microbial factories’ for the production of bioactive secondary metabolites Molecular Biosystems. 5: 567-574. PMID 19462013 DOI: 10.1039/B901287G |
0.302 |
|
2009 |
Garcia RO, Krug D, Müller R. Chapter 3 Discovering Natural Products from Myxobacteria with Emphasis on Rare Producer Strains in Combination with Improved Analytical Methods Methods in Enzymology. 458: 59-91. PMID 19374979 DOI: 10.1016/S0076-6879(09)04803-4 |
0.312 |
|
2009 |
Krug D, Müller R. Discovery of additional members of the tyrosine aminomutase enzyme family and the mutational analysis of CmdF Chembiochem. 10: 741-750. PMID 19222035 DOI: 10.1002/Cbic.200800748 |
0.312 |
|
2009 |
Müller R. Biosynthesis and Heterologous Production of Epothilones Progress in the Chemistry of Organic Natural Products. ProgrèS Dans La Chimie Des Substances Organiques Naturelles. 90: 29-53. PMID 19209840 DOI: 10.1007/978-3-211-78207-1_2 |
0.346 |
|
2009 |
Rachid S, Scharfe M, Blöcker H, Weissman KJ, Müller R. Unusual Chemistry in the Biosynthesis of the Antibiotic Chondrochlorens Chemistry & Biology. 16: 70-81. PMID 19171307 DOI: 10.1016/J.Chembiol.2008.11.005 |
0.346 |
|
2009 |
Perlova O, Gerth K, Kuhlmann S, Zhang Y, Müller R. Novel expression hosts for complex secondary metabolite megasynthetases: Production of myxochromide in the thermopilic isolate Corallococcus macrosporus GT-2. Microbial Cell Factories. 8: 1. PMID 19126236 DOI: 10.1186/1475-2859-8-1 |
0.356 |
|
2009 |
Zöllner A, Dragan CA, Pistorius D, Müller R, Bode HB, Peters FT, Maurer HH, Bureik M. Human CYP4Z1 catalyzes the in-chain hydroxylation of lauric acid and myristic acid. Biological Chemistry. 390: 313-7. PMID 19090726 DOI: 10.1515/Bc.2009.030 |
0.304 |
|
2009 |
Rachid S, Gerth K, Müller R. NtcA: A Negative Regulator of Secondary Metabolite Biosynthesis in Sorangium Cellulosum Journal of Biotechnology. 140: 135-142. PMID 19041909 DOI: 10.1016/J.Jbiotec.2008.10.010 |
0.341 |
|
2009 |
Buedenbender S, Rachid S, Müller R, Schulz GE. Structure and action of the myxobacterial chondrochloren halogenase CndH: a new variant of FAD-dependent halogenases. Journal of Molecular Biology. 385: 520-30. PMID 19000696 DOI: 10.1016/J.Jmb.2008.10.057 |
0.304 |
|
2009 |
Bode HB, Ring MW, Schwär G, Altmeyer MO, Kegler C, Jose IR, Singer M, Müller R. Identification of additional players in the alternative biosynthesis pathway to isovaleryl-CoA in the myxobacterium Myxococcus xanthus. Chembiochem : a European Journal of Chemical Biology. 10: 128-40. PMID 18846531 DOI: 10.1002/Cbic.200800219 |
0.356 |
|
2008 |
Wenzel SC, Bode HB, Kochems I, Müller R. A type I/type III polyketide synthase hybrid biosynthetic pathway for the structurally unique ansa compound kendomycin. Chembiochem : a European Journal of Chemical Biology. 9: 2711-21. PMID 18972512 DOI: 10.1002/Cbic.200800456 |
0.383 |
|
2008 |
Menche D, Arikan F, Perlova O, Horstmann N, Ahlbrecht W, Wenzel SC, Jansen R, Irschik H, Müller R. Stereochemical determination and complex biosynthetic assembly of etnangien, a highly potent RNA polymerase inhibitor from the myxobacterium Sorangium cellulosum. Journal of the American Chemical Society. 130: 14234-43. PMID 18826315 DOI: 10.1021/Ja804194C |
0.34 |
|
2008 |
Meiser P, Weissman KJ, Bode HB, Krug D, Dickschat JS, Sandmann A, Müller R. DKxanthene biosynthesis--understanding the basis for diversity-oriented synthesis in myxobacterial secondary metabolism. Chemistry & Biology. 15: 771-81. PMID 18721748 DOI: 10.1016/J.Chembiol.2008.06.005 |
0.563 |
|
2008 |
Krug D, Zurek G, Schneider B, Garcia R, Müller R. Efficient mining of myxobacterial metabolite profiles enabled by liquid chromatography-electrospray ionisation-time-of-flight mass spectrometry and compound-based principal component analysis. Analytica Chimica Acta. 624: 97-106. PMID 18706314 DOI: 10.1016/J.Aca.2008.06.036 |
0.307 |
|
2008 |
Fu J, Wenzel SC, Perlova O, Wang J, Gross F, Tang Z, Yin Y, Stewart AF, Müller R, Zhang Y. Efficient transfer of two large secondary metabolite pathway gene clusters into heterologous hosts by transposition. Nucleic Acids Research. 36: e113. PMID 18701643 DOI: 10.1093/Nar/Gkn499 |
0.312 |
|
2008 |
Sandmann A, Frank B, Müller R. A transposon-based strategy to scale up myxothiazol production in myxobacterial cell factories. Journal of Biotechnology. 135: 255-61. PMID 18555551 DOI: 10.1016/J.Jbiotec.2008.05.001 |
0.367 |
|
2008 |
Li Y, Weissman KJ, Müller R. Myxochelin biosynthesis: direct evidence for two- and four-electron reduction of a carrier protein-bound thioester. Journal of the American Chemical Society. 130: 7554-7555. PMID 18498160 DOI: 10.1021/Ja8025278 |
0.341 |
|
2008 |
Bock M, Buntin K, Müller R, Kirschning A. Stereochemical determination of thuggacins A-C, highly active antibiotics from the myxobacterium Sorangium cellulosum. Angewandte Chemie (International Ed. in English). 47: 2308-11. PMID 18275054 DOI: 10.1002/Anie.200704897 |
0.484 |
|
2008 |
Petkovi? H, Sandmann A, Challis IR, Hecht HJ, Silakowski B, Low L, Beeston N, Kuscer E, Garcia-Bernardo J, Leadlay PF, Kendrew SG, Wilkinson B, Müller R. Substrate specificity of the acyl transferase domains of EpoC from the epothilone polyketide synthase. Organic & Biomolecular Chemistry. 6: 500-6. PMID 18219420 DOI: 10.1039/B714804F |
0.7 |
|
2008 |
Nawrath T, Dickschat JS, Müller R, Jiang J, Cane DE, Schulz S. Identification of (8S,9S,10S)-8,10-dimethyl-1-octalin, a key intermediate in the biosynthesis of geosmin in bacteria. Journal of the American Chemical Society. 130: 430-1. PMID 18095691 DOI: 10.1021/Ja077790Y |
0.617 |
|
2008 |
Jenke-Kodama H, Müller R, Dittmann E. Evolutionary mechanisms underlying secondary metabolite diversity. Progress in Drug Research. 65: 119-140. PMID 18084914 DOI: 10.1007/978-3-7643-8117-2_3 |
0.302 |
|
2008 |
Dickschat JS, Nawrath T, Thiel V, Kunze B, Müller R, Schulz S. Biosynthesis of the off-flavor 2-methylisoborneol by the myxobacterium Nannocystis exedens. Angewandte Chemie (International Ed. in English). 46: 8287-90. PMID 17899580 DOI: 10.1002/Anie.200702496 |
0.608 |
|
2008 |
Bock M, Buntin K, Müller R, Kirschning A. Bestimmung der relativen und absoluten Konfiguration von Thuggacin A–C, hochaktiven Antibiotika aus dem Myxobakterium Sorangium cellulosum Angewandte Chemie. 120: 2341-2344. DOI: 10.1002/Ange.200704897 |
0.439 |
|
2007 |
Wenzel SC, Müller R. Myxobacterial natural product assembly lines: fascinating examples of curious biochemistry. Natural Product Reports. 24: 1211-1224. PMID 18033576 DOI: 10.1039/B706416K |
0.307 |
|
2007 |
Schneiker S, Perlova O, Kaiser O, Gerth K, Alici A, Altmeyer MO, Bartels D, Bekel T, Beyer S, Bode E, Bode HB, Bolten CJ, Choudhuri JV, Doss S, Elnakady YA, et al. Complete genome sequence of the myxobacterium Sorangium cellulosum. Nature Biotechnology. 25: 1281-9. PMID 17965706 DOI: 10.1038/Nbt1354 |
0.519 |
|
2007 |
Bode HB, Meiser P, Klefisch T, Cortina NS, Krug D, Göhring A, Schwär G, Mahmud T, Elnakady YA, Müller R. Mutasynthesis-derived myxalamids and origin of the isobutyryl-CoA starter unit of myxalamid B. Chembiochem : a European Journal of Chemical Biology. 8: 2139-44. PMID 17955482 DOI: 10.1002/Cbic.200700401 |
0.548 |
|
2007 |
Frank B, Wenzel SC, Bode HB, Scharfe M, Blöcker H, Müller R. From Genetic Diversity to Metabolic Unity: Studies on the Biosynthesis of Aurafurones and Aurafuron-like Structures in Myxobacteria and Streptomycetes Journal of Molecular Biology. 374: 24-38. PMID 17919655 DOI: 10.1016/J.Jmb.2007.09.015 |
0.38 |
|
2007 |
Elnakady YA, Rohde M, Sasse F, Backes C, Keller A, Lenhof H, Weissman KJ, Müller R. Evidence for the mode of action of the highly cytotoxic Streptomyces polyketide kendomycin. Chembiochem. 8: 1261-1272. PMID 17592829 DOI: 10.1002/Cbic.200700050 |
0.307 |
|
2007 |
Simunovic V, Müller R. Mutational Analysis of the Myxovirescin Biosynthetic Gene Cluster Reveals Novel Insights into the Functional Elaboration of Polyketide Backbones Chembiochem. 8: 1273-1280. PMID 17583882 DOI: 10.1002/Cbic.200700153 |
0.313 |
|
2007 |
Rachid S, Krug D, Weissman KJ, Müller R. Biosynthesis of (R)-β-tyrosine and its incorporation into the highly cytotoxic chondramides produced by Chondromyces crocatus Journal of Biological Chemistry. 282: 21810-21817. PMID 17545150 DOI: 10.1074/Jbc.M703439200 |
0.305 |
|
2007 |
Rachid S, Gerth K, Kochems I, Müller R. Deciphering regulatory mechanisms for secondary metabolite production in the myxobacterium Sorangium cellulosum So ce56. Molecular Microbiology. 63: 1783-1796. PMID 17367395 DOI: 10.1111/J.1365-2958.2007.05627.X |
0.359 |
|
2007 |
Martens T, Gram L, Grossart HP, Kessler D, Müller R, Simon M, Wenzel SC, Brinkhoff T. Bacteria of the Roseobacter clade show potential for secondary metabolite production. Microbial Ecology. 54: 31-42. PMID 17351813 DOI: 10.1007/S00248-006-9165-2 |
0.354 |
|
2007 |
Sandmann A, Dickschat J, Jenke-Kodama H, Kunze B, Dittmann E, Müller R. A Type II polyketide synthase from the gram-negative Bacterium Stigmatella aurantiaca is involved in Aurachin alkaloid biosynthesis. Angewandte Chemie (International Ed. in English). 46: 2712-6. PMID 17335090 DOI: 10.1002/Anie.200603513 |
0.507 |
|
2007 |
Simunovic V, Müller R. 3-hydroxy-3-methylglutaryl-CoA-like synthases direct the formation of methyl and ethyl side groups in the biosynthesis of the antibiotic myxovirescin A. Chembiochem. 8: 497-500. PMID 17330904 DOI: 10.1002/Cbic.200700017 |
0.309 |
|
2007 |
Frank B, Knauber J, Steinmetz H, Scharfe M, Blöcker H, Beyer S, Müller R. Spiroketal Polyketide Formation in Sorangium: Identification and Analysis of the Biosynthetic Gene Cluster for the Highly Cytotoxic Spirangienes Chemistry & Biology. 14: 221-233. PMID 17317575 DOI: 10.1016/J.Chembiol.2006.11.013 |
0.377 |
|
2007 |
Dickschat JS, Nawrath T, Thiel V, Kunze B, Müller R, Schulz S. Biosynthese des Duftstoffes 2-Methylisoborneol durch das MyxobakteriumNannocystis exedens Angewandte Chemie. 119: 8436-8439. DOI: 10.1002/Ange.200702496 |
0.556 |
|
2006 |
Gross F, Ring MW, Perlova O, Fu J, Schneider S, Gerth K, Kuhlmann S, Stewart AF, Zhang Y, Müller R. Metabolic engineering of Pseudomonas putida for methylmalonyl-CoA biosynthesis to enable complex heterologous secondary metabolite formation. Chemistry & Biology. 13: 1253-64. PMID 17185221 DOI: 10.1016/J.Chembiol.2006.09.014 |
0.341 |
|
2006 |
Meiser P, Bode HB, Müller R. The unique DKxanthene secondary metabolite family from the myxobacterium Myxococcus xanthus is required for developmental sporulation Proceedings of the National Academy of Sciences of the United States of America. 103: 19128-19133. PMID 17148609 DOI: 10.1073/Pnas.0606039103 |
0.336 |
|
2006 |
Schley C, Altmeyer MO, Swart R, Müller R, Huber CG. Proteome Analysis of Myxococcus xanthus by Off-Line Two-Dimensional Chromatographic Separation Using Monolithic Poly-(styrene-divinylbenzene) Columns Combined with Ion-Trap Tandem Mass Spectrometry Journal of Proteome Research. 5: 2760-2768. PMID 17022647 DOI: 10.1021/Pr0602489 |
0.322 |
|
2006 |
Perlova O, Fu J, Kuhlmann S, Krug D, Stewart AF, Zhang Y, Müller R. Reconstitution of the myxothiazol biosynthetic gene cluster by red/ET recombination and heterologous expression in Myxococcus xanthus Applied and Environmental Microbiology. 72: 7485-7494. PMID 16997979 DOI: 10.1128/Aem.01503-06 |
0.341 |
|
2006 |
Bode HB, Ring MW, Schwär G, Kroppenstedt RM, Kaiser D, Müller R. 3-Hydroxy-3-methylglutaryl-coenzyme A (CoA) synthase is involved in biosynthesis of isovaleryl-CoA in the myxobacterium Myxococcus xanthus during fruiting body formation. Journal of Bacteriology. 188: 6524-8. PMID 16952943 DOI: 10.1128/Jb.00825-06 |
0.359 |
|
2006 |
Müller I, Müller R. Biochemical characterization of MelJ and MelK Febs Journal. 273: 3768-3778. PMID 16911525 DOI: 10.1111/J.1742-4658.2006.05385.X |
0.349 |
|
2006 |
Simunovic V, Zapp J, Rachid S, Krug D, Meiser P, Müller R. Myxovirescin A biosynthesis is directed by hybrid polyketide synthases/nonribosomal peptide synthetase, 3-hydroxy-3-methylglutaryl-CoA synthases, and trans-acting acyltransferases Chembiochem. 7: 1206-1220. PMID 16835859 DOI: 10.1002/Cbic.200600075 |
0.367 |
|
2006 |
Müller I, Weinig S, Steinmetz H, Kunze B, Veluthoor S, Mahmud T, Müller R. A unique mechanism for methyl ester formation via an amide intermediate found in myxobacteria. Chembiochem : a European Journal of Chemical Biology. 7: 1197-205. PMID 16807964 DOI: 10.1002/Cbic.200600057 |
0.569 |
|
2006 |
Rachid S, Krug D, Kunze B, Kochems I, Scharfe M, Zabriskie TM, Blöcker H, Müller R. Molecular and biochemical studies of chondramide formation-highly cytotoxic natural products from Chondromyces crocatus Cm c5. Chemistry & Biology. 13: 667-81. PMID 16793524 DOI: 10.1016/J.Chembiol.2006.06.002 |
0.355 |
|
2006 |
Berner M, Krug D, Bihlmaier C, Vente A, Müller R, Bechthold A. Genes and enzymes involved in caffeic acid biosynthesis in the actinomycete Saccharothrix espanaensis. Journal of Bacteriology. 188: 2666-73. PMID 16547054 DOI: 10.1128/Jb.188.7.2666-2673.2006 |
0.321 |
|
2006 |
Bode HB, Müller R. Analysis of myxobacterial secondary metabolism goes molecular Journal of Industrial Microbiology and Biotechnology. 33: 577-588. PMID 16491362 DOI: 10.1007/S10295-006-0082-7 |
0.319 |
|
2006 |
Gross F, Luniak N, Perlova O, Gaitatzis N, Jenke-Kodama H, Gerth K, Gottschalk D, Dittmann E, Müller R. Bacterial type III polyketide synthases: phylogenetic analysis and potential for the production of novel secondary metabolites by heterologous expression in pseudomonads. Archives of Microbiology. 185: 28-38. PMID 16395556 DOI: 10.1007/S00203-005-0059-3 |
0.339 |
|
2006 |
Fauti T, Müller‐Brüsselbach S, Kreutzer M, Rieck M, Meissner W, Rapp U, Schweer H, Kömhoff M, Müller R. Induction of PPARβ and prostacyclin (PGI2) synthesis by Raf signaling: failure of PGI2 to activate PPARβ Febs Journal. 273: 170-179. PMID 16367757 DOI: 10.1111/J.1742-4658.2005.05055.X |
0.314 |
|
2006 |
Müller R, Gerth K. Development of simple media which allow investigations into the global regulation of chivosazol biosynthesis with Sorangium cellulosum So ce56 Journal of Biotechnology. 121: 192-200. PMID 16321454 DOI: 10.1016/J.Jbiotec.2005.10.012 |
0.314 |
|
2006 |
Perlova O, Gerth K, Kaiser O, Hans A, Müller R. Identification and analysis of the chivosazol biosynthetic gene cluster from the myxobacterial model strain Sorangium cellulosum So ce56. Journal of Biotechnology. 121: 174-191. PMID 16313990 DOI: 10.1016/J.Jbiotec.2005.10.011 |
0.367 |
|
2006 |
Rachid S, Sasse F, Beyer S, Müller R. Identification of StiR, the first regulator of secondary metabolite formation in the myxobacterium Cystobacter fuscus Cb f17.1. Journal of Biotechnology. 121: 429-441. PMID 16221500 DOI: 10.1016/J.Jbiotec.2005.08.014 |
0.36 |
|
2006 |
Stephan S, Heinzle E, Wenzel SC, Krug D, Müller R, Wittmann C. Metabolic physiology of Pseudomonas putida for heterologous production of myxochromide Process Biochemistry. 41: 2146-2152. DOI: 10.1016/J.Procbio.2006.06.022 |
0.358 |
|
2006 |
Wenzel SC, Meiser P, Binz TM, Mahmud T, Müller R. Nichtribosomale Peptidbiosynthese: Punktmutationen und Überspringen eines Moduls führen zu chemischer Diversität Angewandte Chemie. 118: 2354-2360. DOI: 10.1002/Ange.200503737 |
0.454 |
|
2005 |
Bode HB, Müller R. The impact of bacterial genomics on natural product research Angewandte Chemie - International Edition. 44: 6828-6846. PMID 16249991 DOI: 10.1002/Anie.200501080 |
0.306 |
|
2005 |
Wenzel SC, Müller R. Recent developments towards the heterologous expression of complex bacterial natural product biosynthetic pathways. Current Opinion in Biotechnology. 16: 594-606. PMID 16226455 DOI: 10.1016/J.Copbio.2005.10.001 |
0.359 |
|
2005 |
Dickschat JS, Bode HB, Wenzel SC, Müller R, Schulz S. Biosynthesis and identification of volatiles released by the myxobacterium Stigmatella aurantiaca Chembiochem. 6: 2023-2033. PMID 16208730 DOI: 10.1002/Cbic.200500174 |
0.618 |
|
2005 |
Wenzel SC, Müller R. Formation of novel secondary metabolites by bacterial multimodular assembly lines: deviations from textbook biosynthetic logic. Current Opinion in Chemical Biology. 9: 447-458. PMID 16107321 DOI: 10.1016/J.Cbpa.2005.08.001 |
0.326 |
|
2005 |
Dickschat JS, Bode HB, Kroppenstedt RM, Müller R, Schulz S. Biosynthesis of iso-fatty acids in myxobacteria Organic and Biomolecular Chemistry. 3: 2824-2831. PMID 16032360 DOI: 10.1039/B504889C |
0.603 |
|
2005 |
Dickschat JS, Bode HB, Mahmud T, Müller R, Schulz S. A novel type of geosmin biosynthesis in myxobacteria. The Journal of Organic Chemistry. 70: 5174-82. PMID 15960521 DOI: 10.1021/Jo050449G |
0.701 |
|
2005 |
Jenke-Kodama H, Sandmann A, Müller R, Dittmann E. Evolutionary implications of bacterial polyketide synthases. Molecular Biology and Evolution. 22: 2027-39. PMID 15958783 DOI: 10.1093/Molbev/Msi193 |
0.372 |
|
2005 |
Bredenbruch F, Nimtz M, Wray V, Morr M, Müller R, Häussler S. Biosynthetic Pathway of Pseudomonas aeruginosa 4-Hydroxy-2-Alkylquinolines Journal of Bacteriology. 187: 3630-3635. PMID 15901684 DOI: 10.1128/Jb.187.11.3630-3635.2005 |
0.305 |
|
2005 |
Gerth K, Müller R. Moderately thermophilic Myxobacteria: novel potential for the production of natural products isolation and characterization. Environmental Microbiology. 7: 874-880. PMID 15892706 DOI: 10.1111/J.1462-2920.2005.00761.X |
0.307 |
|
2005 |
Kopp M, Irschik H, Pradella S, Müller R. Production of the tubulin destabilizer disorazol in Sorangium cellulosum: biosynthetic machinery and regulatory genes. Chembiochem. 6: 1277-1286. PMID 15892181 DOI: 10.1002/Cbic.200400459 |
0.384 |
|
2005 |
Wenzel SC, Gross F, Zhang Y, Fu J, Stewart AF, Müller R. Heterologous expression of a myxobacterial natural products assembly line in pseudomonads via red/ET recombineering. Chemistry & Biology. 12: 349-56. PMID 15797219 DOI: 10.1016/J.Chembiol.2004.12.012 |
0.344 |
|
2005 |
Gaitatzis N, Kunze B, Müller R. Novel insights into siderophore formation in myxobacteria. Chembiochem. 6: 365-374. PMID 15678426 DOI: 10.1002/Cbic.200400206 |
0.363 |
|
2005 |
Wenzel SC, Kunze B, Höfle G, Silakowski B, Scharfe M, Blöcker H, Müller R. Structure and biosynthesis of myxochromides S1-3 in Stigmatella aurantiaca: evidence for an iterative bacterial type I polyketide synthase and for module skipping in nonribosomal peptide biosynthesis. Chembiochem. 6: 375-385. PMID 15651040 DOI: 10.1002/Cbic.200400282 |
0.352 |
|
2005 |
Bode HB, Dickschat JS, Kroppenstedt RM, Schulz S, Müller R. Biosynthesis of iso-fatty acids in myxobacteria: Iso-even fatty acids are derived by α-oxidation from iso-odd fatty acids Journal of the American Chemical Society. 127: 532-533. PMID 15643871 DOI: 10.1021/Ja043570Y |
0.595 |
|
2005 |
Mahmud T, Wenzel SC, Wan E, Wen KW, Bode HB, Gaitatzis N, Müller R. A biosynthetic pathway to isovaleryl-CoA in myxobacteria: the involvement of the mevalonate pathway. Chembiochem : a European Journal of Chemical Biology. 6: 322-30. PMID 15619721 DOI: 10.1002/Cbic.200400261 |
0.564 |
|
2005 |
Dickschat JS, Wenzel SC, Bode HB, Müller R, Schulz S. Biosynthesis of volatiles by the myxobacterium Myxococcus xanthus. Chembiochem : a European Journal of Chemical Biology. 5: 778-87. PMID 15174160 DOI: 10.1002/Cbic.200300813 |
0.624 |
|
2004 |
Sandmann A, Sasse F, Müller R. Identification and analysis of the core biosynthetic machinery of tubulysin, a potent cytotoxin with potential anticancer activity. Chemistry & Biology. 11: 1071-9. PMID 15324808 DOI: 10.1016/J.Chembiol.2004.05.014 |
0.356 |
|
2004 |
Bode HB, Wenzel SC, Irschik H, Höfle G, Müller R. Unusual biosynthesis of leupyrrins in the myxobacterium Sorangium cellulosum. Angewandte Chemie. 43: 4163-4167. PMID 15307077 DOI: 10.1002/Anie.200454240 |
0.303 |
|
2004 |
Kopp M, Irschik H, Gross F, Perlova O, Sandmann A, Gerth K, Müller R. Critical variations of conjugational DNA transfer into secondary metabolite multiproducing Sorangium cellulosum strains So ce12 and So ce56: development of a mariner-based transposon mutagenesis system. Journal of Biotechnology. 107: 29-40. PMID 14687969 DOI: 10.1016/J.Jbiotec.2003.09.013 |
0.329 |
|
2004 |
Burchert A, Cai D, Hofbauer LC, Samuelsson MK, Slater EP, Duyster J, Ritter M, Hochhaus A, Müller R, Eilers M, Schmidt M, Neubauer A. Interferon consensus sequence binding protein (ICSBP; IRF-8) antagonizes BCR/ABL and down-regulates bcl-2. Blood. 103: 3480-9. PMID 14656881 DOI: 10.1182/Blood-2003-08-2970 |
0.303 |
|
2003 |
Gerth K, Pradella S, Perlova O, Beyer S, Müller R. Myxobacteria: proficient producers of novel natural products with various biological activities--past and future biotechnological aspects with the focus on the genus Sorangium. Journal of Biotechnology. 106: 233-253. PMID 14651865 DOI: 10.1016/J.Jbiotec.2003.07.015 |
0.341 |
|
2003 |
Weinig S, Mahmud T, Müller R. Markerless mutations in the myxothiazol biosynthetic gene cluster: a delicate megasynthetase with a superfluous nonribosomal peptide synthetase domain. Chemistry & Biology. 10: 953-60. PMID 14583261 DOI: 10.1016/J.Chembiol.2003.09.013 |
0.554 |
|
2003 |
Weinig S, Hecht HJ, Mahmud T, Müller R. Melithiazol biosynthesis: further insights into myxobacterial PKS/NRPS systems and evidence for a new subclass of methyl transferases. Chemistry & Biology. 10: 939-52. PMID 14583260 DOI: 10.1016/J.Chembiol.2003.09.012 |
0.534 |
|
2003 |
Franke D, Lorbach V, Esser S, Dose C, Sprenger GA, Halfar M, Thömmes J, Müller R, Takors R, Müller M. (S,S)-2,3-Dihydroxy-2,3-dihydrobenzoic acid: microbial access with engineered cells of Escherichia coli and application as starting material in natural-product synthesis. Chemistry: a European Journal. 9: 4188-4196. PMID 12953204 DOI: 10.1002/Chem.200204265 |
0.355 |
|
2003 |
Takikawa H, Mafune KI, Hamada H, Nettelbeck DM, Müller R, Makuuchi M, Kaminishi M. An advanced strategy of enhanced specific gene expression for hepatocellular carcinoma. International Journal of Oncology. 22: 1051-1056. DOI: 10.3892/Ijo.22.5.1051 |
0.305 |
|
2002 |
Arakawa K, Müller R, Mahmud T, Yu TW, Floss HG. Characterization of the early stage aminoshikimate pathway in the formation of 3-amino-5-hydroxybenzoic acid: the RifN protein specifically converts kanosamine into kanosamine 6-phosphate. Journal of the American Chemical Society. 124: 10644-5. PMID 12207505 DOI: 10.1021/Ja0206339 |
0.653 |
|
2002 |
Mahmud T, Bode HB, Silakowski B, Kroppenstedt RM, Xu M, Nordhoff S, Höfle G, Müller R. A novel biosynthetic pathway providing precursors for fatty acid biosynthesis and secondary metabolite formation in myxobacteria. The Journal of Biological Chemistry. 277: 32768-74. PMID 12084727 DOI: 10.1074/Jbc.M205222200 |
0.544 |
|
2002 |
Gaitatzis N, Silakowski B, Kunze B, Nordsiek G, Blöcker H, Höfle G, Müller R. The Biosynthesis of the Aromatic Myxobacterial Electron Transport Inhibitor Stigmatellin Is Directed by a Novel Type of Modular Polyketide Synthase Journal of Biological Chemistry. 277: 13082-13090. PMID 11809757 DOI: 10.1074/Jbc.M111738200 |
0.351 |
|
2001 |
Buss K, Müller R, Dahm C, Gaitatzis N, Skrzypczak-Pietraszek E, Lohmann S, Gassen M, Leistner E. Clustering of isochorismate synthase genes menF and entC and channeling of isochorismate in Escherichia coli. Biochimica Et Biophysica Acta. 1522: 151-7. PMID 11779629 DOI: 10.1016/S0167-4781(01)00325-6 |
0.611 |
|
2001 |
Silakowski B, Kunze B, Müller R. Multiple hybrid polyketide synthase/non-ribosomal peptide synthetase gene clusters in the myxobacterium Stigmatella aurantiaca. Gene. 275: 233-240. PMID 11587850 DOI: 10.1016/S0378-1119(01)00680-1 |
0.372 |
|
2001 |
Gaitatzis N, Kunze B, Müller R. In vitro reconstitution of the myxochelin biosynthetic machinery of Stigmatella aurantiaca Sg a15: Biochemical characterization of a reductive release mechanism from nonribosomal peptide synthetases Proceedings of the National Academy of Sciences of the United States of America. 98: 11136-11141. PMID 11562468 DOI: 10.1073/Pnas.201167098 |
0.342 |
|
2001 |
Jérôme V, Müller R. A synthetic leucine zipper-based dimerization system for combining multiple promoter specificities. Gene Therapy. 8: 725-729. PMID 11406767 DOI: 10.1038/Sj.Gt.3301443 |
0.316 |
|
2001 |
Yu TW, Muller R, Muller M, Zhang X, Draeger G, Kim CG, Leistner E, Floss HG. Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699. The Journal of Biological Chemistry. 276: 12546-55. PMID 11278540 DOI: 10.1074/Jbc.M009667200 |
0.703 |
|
2001 |
Silakowski B, Nordsiek G, Kunze B, Blöcker H, Müller R. Novel features in a combined polyketide synthase/non-ribosomal peptide synthetase: the myxalamid biosynthetic gene cluster of the myxobacterium Stigmatella aurantiaca Sga15. Chemistry & Biology. 8: 59-69. PMID 11182319 DOI: 10.1016/S1074-5521(00)00056-9 |
0.372 |
|
2001 |
Gaitatzis N, Hans A, Müller R, Beyer S. The mtaA Gene of the Myxothiazol Biosynthetic Gene Cluster from Stigmatella aurantiaca DW4/3-1 Encodes a Phosphopantetheinyl Transferase that Activates Polyketide Synthases and Polypeptide Synthetases. Journal of Biochemistry. 129: 119-124. PMID 11134965 DOI: 10.1093/Oxfordjournals.Jbchem.A002821 |
0.34 |
|
2000 |
Silakowski B, Kunze B, Nordsiek G, Blöcker H, Höfle G, Müller R. The myxochelin iron transport regulon of the myxobacterium Stigmatella aurantiaca Sg a15. Febs Journal. 267: 6476-6485. PMID 11029592 DOI: 10.1046/J.1432-1327.2000.01740.X |
0.319 |
|
2000 |
Müller R, Gerth K, Brandt P, Blöcker H, Beyer S. Identification of an L-dopa decarboxylase gene from Sorangium cellulosum So ce90. Archives of Microbiology. 173: 303-306. PMID 10816050 DOI: 10.1007/S002039900131 |
0.333 |
|
1999 |
Silakowski B, Schairer HU, Ehret H, Kunze B, Weinig S, Nordsiek G, Brandt P, Blöcker H, Höfle G, Beyer S, Müller R. New lessons for combinatorial biosynthesis from myxobacteria. The myxothiazol biosynthetic gene cluster of Stigmatella aurantiaca DW4/3-1. Journal of Biological Chemistry. 274: 37391-37399. PMID 10601310 DOI: 10.1074/Jbc.274.52.37391 |
0.365 |
|
1999 |
Beyer S, Kunze B, Silakowski B, Müller R. Metabolic diversity in myxobacteria: identification of the myxalamid and the stigmatellin biosynthetic gene cluster of Stigmatella aurantiaca Sg a15 and a combined polyketide-(poly)peptide gene cluster from the epothilone producing strain Sorangium cellulosum So ce90. Biochimica Et Biophysica Acta. 1445: 185-195. PMID 10320771 DOI: 10.1016/S0167-4781(99)00041-X |
0.359 |
|
1999 |
Chen S, von Bamberg D, Hale V, Breuer M, Hardt B, Müller R, Floss HG, Reynolds KA, Leistner E. Biosynthesis of ansatrienin (mycotrienin) and naphthomycin. Identification and analysis of two separate biosynthetic gene clusters in Streptomyces collinus Tü 1892. European Journal of Biochemistry / Febs. 261: 98-107. PMID 10103039 DOI: 10.1046/J.1432-1327.1999.00244.X |
0.7 |
|
1999 |
Graulich W, Nettelbeck DM, Fischer D, Kissel T, Müller R. Cell type specificity of the human endoglin promoter Gene. 227: 55-62. PMID 9931433 DOI: 10.1016/S0378-1119(98)00585-X |
0.318 |
|
1998 |
Dahm C, Müller R, Schulte G, Schmidt K, Leistner E. The role of isochorismate hydroxymutase genes entC and menF in enterobactin and menaquinone biosynthesis in Escherichia coli Biochimica Et Biophysica Acta. 1425: 377-386. PMID 9795253 DOI: 10.1016/S0304-4165(98)00089-0 |
0.634 |
|
1998 |
August PR, Tang L, Yoon YJ, Ning S, Müller R, Yu TW, Taylor M, Hoffmann D, Kim CG, Zhang X, Hutchinson CR, Floss HG. Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699. Chemistry & Biology. 5: 69-79. PMID 9512878 DOI: 10.1016/S1074-5521(98)90141-7 |
0.555 |
|
1998 |
Müller M, Müller R, Yu TW, Floss HG. Synthesis of (-)-3-amino-3-deoxyquinic acid Journal of Organic Chemistry. 63: 9753-9755. DOI: 10.1021/Jo981291L |
0.497 |
|
1997 |
Rönicke V, Graulich W, Mumberg D, Müller R, Funk M. Use of conditional promoters for expression of heterologous proteins in Saccharomyces cerevisiae Methods in Enzymology. 283: 313-322. PMID 9251029 DOI: 10.1016/S0076-6879(97)83025-X |
0.323 |
|
1997 |
Ledüc C, Birgel I, Müller R, Leistner E. Isochorismate hydroxymutase from a cell-suspension culture of Galium mollugo L. Planta. 202: 206-210. DOI: 10.1007/S004250050120 |
0.576 |
|
1996 |
Müller R, Breuer M, Wagener A, Schmidt K, Leistner E. Bacterial production of transdihydroxycyclohexadiene carboxylates by metabolic pathway engineering. Microbiology (Reading, England). 142: 1005-1012. PMID 8936326 DOI: 10.1099/00221287-142-4-1005 |
0.618 |
|
1996 |
Müller R, Kuttler E, Lanz C, Drewke C, Schmidt K. Isolation of a gene encoding cysteine synthase from Flavobacterium K3–15 Fems Microbiology Letters. 136: 305-308. PMID 8867384 DOI: 10.1111/J.1574-6968.1996.Tb08065.X |
0.34 |
|
1996 |
Mazhari-Tabrizi R, Eckert V, Blank M, Müller R, Mumberg D, Funk M, Schwarz RT. Cloning and functional expression of glycosyltransferases from parasitic protozoans by heterologous complementation in yeast: the dolichol phosphate mannose synthase from Trypanosoma brucei brucei * Biochemical Journal. 316: 853-858. PMID 8670162 DOI: 10.1042/Bj3160853 |
0.303 |
|
1996 |
Müller R, Dahm C, Schulte G, Leistner E. An isochorismate hydroxymutase isogene in Escherichia coli Febs Letters. 378: 131-134. PMID 8549818 DOI: 10.1016/0014-5793(95)01436-5 |
0.622 |
|
1995 |
Müller R, Wagener A, Schmidt K, Leistner E. Microbial production of specifically ring-13C-labelled 4-hydroxybenzoic acid. Applied Microbiology and Biotechnology. 43: 985-988. PMID 8590665 DOI: 10.1007/Bf00166913 |
0.615 |
|
1995 |
Wick M, Bürger C, Funk M, Müller R. Identification of a Novel Mitogen-Inducible Gene (mig-6): Regulation during G1 Progression and Differentiation Experimental Cell Research. 219: 527-535. PMID 7641805 DOI: 10.1006/Excr.1995.1261 |
0.321 |
|
1995 |
Wick M, Härönen R, Mumberg D, Bürger C, Olsen BR, Budarf ML, Apte SS, Müller R. Structure of the human TIMP-3 gene and its cell cycle-regulated promoter. The Biochemical Journal. 549-54. PMID 7487894 DOI: 10.1042/Bj3110549 |
0.306 |
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1995 |
Zwicker J, Lucibello FC, Wolfraim LA, Gross C, Truss M, Engeland K, Müller R. Cell cycle regulation of the cyclin A, cdc25C and cdc2 genes is based on a common mechanism of transcriptional repression. The Embo Journal. 14: 4514-4522. DOI: 10.1002/J.1460-2075.1995.Tb00130.X |
0.304 |
|
1992 |
Stoffel W, Müller R, Binczek E, Hofmann K. Mouse apolipoprotein AI. cDNA-derived primary structure, gene organisation and complete nucleotide sequence. Biological Chemistry Hoppe-Seyler. 373: 187-194. PMID 1596360 DOI: 10.1515/Bchm3.1992.373.1.187 |
0.303 |
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1991 |
Schuermann M, Hunter JB, Hennig G, Müller R. Non-leucine residues in the leucine repeats of fos and jun contribute to the stability and determine the specificity of dimerization Nucleic Acids Research. 19: 739-746. PMID 1901988 DOI: 10.1093/Nar/19.4.739 |
0.301 |
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1991 |
Mumberg D, Lucibello FC, Schuermann M, Müller R. Alternative splicing of fosB transcripts results in differentially expressed mRNAs encoding functionally antagonistic proteins. Genes & Development. 5: 1212-1223. PMID 1648531 DOI: 10.1101/Gad.5.7.1212 |
0.306 |
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1989 |
Neuberg M, Schuermann M, Hunter JB, Müller R. Two functionally different regions in Fos are required for the sequence-specific DNA interaction of the Fos/Jun protein complex Nature. 338: 589-590. PMID 2494459 DOI: 10.1038/338589A0 |
0.304 |
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1989 |
Schuermann M, Neuberg M, Hunter JB, Jenuwein T, Ryseck RP, Bravo R, Müller R. The leucine repeat motif in Fos protein mediates complex formation with Jun/AP-1 and is required for transformation Cell. 56: 507-516. PMID 2492453 DOI: 10.1016/0092-8674(89)90253-5 |
0.303 |
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1986 |
Müller R. Cellular and viral fos genes: structure, regulation of expression and biological properties of their encoded products Bba - Reviews On Cancer. 823: 207-225. PMID 3011086 DOI: 10.1016/0304-419X(86)90003-X |
0.318 |
|
1985 |
Mölders H, Defesche J, Müller D, Bonner TI, Rapp UR, Müller R. Integration of transfected LTR sequences into the c-raf proto-oncogene: activation by promoter insertion The Embo Journal. 4: 693-698. DOI: 10.1002/J.1460-2075.1985.Tb03685.X |
0.313 |
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1984 |
Müller R, Müller D. Co-transfection of normal NIH/3T3 DNA and retroval LTR sequences: a novel strategy for the detection of potential c-onc genes. The Embo Journal. 3: 1121-1127. DOI: 10.1002/J.1460-2075.1984.Tb01939.X |
0.312 |
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1983 |
Müller R, Tremblay JM, Adamson ED, Verma IM. Tissue and cell type-specific expression of two human c-onc genes. Nature. 304: 454-6. PMID 6877368 DOI: 10.1038/304454A0 |
0.307 |
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