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James B. McLachlan, Ph.D. - Publications

Affiliations: 
2004 Duke University, Durham, NC 
Area:
Immunology
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34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 First NJ, Parrish KM, Martínez-Pérez A, González-Fernández Á, Bharrhan S, Woolard M, McLachlan JB, Scott RS, Wang J, Gestal MC. Bordetella spp. block eosinophil recruitment to suppress the generation of early mucosal protection. Cell Reports. 42: 113294. PMID 37883230 DOI: 10.1016/j.celrep.2023.113294  0.534
2023 Morici LA, McLachlan JB. Non-mucosal vaccination strategies to enhance mucosal immunity. Vaccine Insights. 2: 229-236. PMID 37881504 DOI: 10.18609/vac.2023.034  0.492
2023 Prior JT, Limbert VM, Horowitz RM, D'Souza SJ, Bachnak L, Godwin MS, Bauer DL, Harrell JE, Morici LA, Taylor JJ, McLachlan JB. Establishment of isotype-switched, antigen-specific B cells in multiple mucosal tissues using non-mucosal immunization. Npj Vaccines. 8: 80. PMID 37258506 DOI: 10.1038/s41541-023-00677-z  0.555
2023 Bauer DL, Bachnak L, Limbert VM, Horowitz RM, Baudier RL, D'Souza SJ, Immethun VE, Kurtz JR, Grant SB, McLachlan JB. The Adjuvant Combination of dmLT and Monophosphoryl Lipid A Activates the Canonical, Nonpyroptotic NLRP3 Inflammasome in Dendritic Cells and Significantly Interacts to Expand Antigen-Specific CD4 T Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 37023458 DOI: 10.4049/jimmunol.2200221  0.576
2022 Zhai B, Clarke K, Bauer DL, Moehling Geffel KK, Kupul S, Schratz LJ, Nowalk MP, McElroy AK, McLachlan JB, Zimmerman RK, Alcorn JF. SARS-CoV-2 Antibody Response Is Associated with Age and Body Mass Index in Convalescent Outpatients. Journal of Immunology (Baltimore, Md. : 1950). PMID 35321882 DOI: 10.4049/jimmunol.2101156  0.323
2021 Zhai B, Clarke K, Bauer DL, Kupul S, Schratz LJ, Nowalk MP, McElroy AK, McLachlan JB, Zimmerman RK, Alcorn JF. SARS-CoV-2 Antibody Response is Associated with Age in Convalescent Outpatients. Medrxiv : the Preprint Server For Health Sciences. PMID 34790986 DOI: 10.1101/2021.11.08.21265888  0.362
2021 Douglas B, Wei Y, Li X, Ferguson A, Hung LY, Pastore C, Kurtz JR, McLachlan JB, Nolan TJ, Lok J, Herbert DR. Transgenic expression of a T cell epitope in Strongyloides ratti reveals that helminth-specific CD4+ T cells constitute both Th2 and Treg populations. Plos Pathogens. 17: e1009709. PMID 34237106 DOI: 10.1371/journal.ppat.1009709  0.307
2021 Harrell JE, Kurtz JR, Bauer DL, Prior JT, Gellings PS, Morici LA, McLachlan JB. An Outer Membrane Vesicle-Adjuvanted Oral Vaccine Protects Against Lethal, Oral Infection. Pathogens (Basel, Switzerland). 10. PMID 34069796 DOI: 10.3390/pathogens10050616  0.466
2021 Phong BL, D'Souza SJ, Baudier RL, Wu E, Immethun VE, Bauer DL, McLachlan JB. IgE-activated mast cells enhance TLR4-mediated antigen-specific CD4 T cell responses. Scientific Reports. 11: 9686. PMID 33958642 DOI: 10.1038/s41598-021-88956-4  0.539
2021 Baker SM, Settles EW, Davitt C, Gellings P, Kikendall N, Hoffmann J, Wang Y, Bitoun J, Lodrigue KR, Sahl JW, Keim P, Roy C, McLachlan J, Morici LA. Burkholderia pseudomallei OMVs derived from infection mimicking conditions elicit similar protection to a live-attenuated vaccine. Npj Vaccines. 6: 18. PMID 33514749 DOI: 10.1038/s41541-021-00281-z  0.48
2021 Prior JT, Davitt C, Kurtz J, Gellings P, McLachlan JB, Morici LA. Bacterial-Derived Outer Membrane Vesicles are Potent Adjuvants that Drive Humoral and Cellular Immune Responses. Pharmaceutics. 13. PMID 33498352 DOI: 10.3390/pharmaceutics13020131  0.626
2020 Harrell JE, Hahn MM, D'Souza SJ, Vasicek EM, Sandala JL, Gunn JS, McLachlan JB. Biofilm Formation, Chronic Infection, and Immunity Within the Intestine and Hepatobiliary Tract. Frontiers in Cellular and Infection Microbiology. 10: 624622. PMID 33604308 DOI: 10.3389/fcimb.2020.624622  0.444
2020 Goggins JA, Kurtz JR, McLachlan JB. Control of Persistent Infection Relies on Constant Thymic Output Despite Increased Peripheral Antigen-Specific T Cell Immunity. Pathogens (Basel, Switzerland). 9. PMID 32722409 DOI: 10.3390/pathogens9080605  0.446
2020 Kurtz JR, Nieves W, Bauer D, Israel K, Adcox HE, Gunn JS, Morici LA, McLachlan JB. Persistence and Host Immunity is Dictated by the Anatomical Microenvironment. Infection and Immunity. PMID 32393507 DOI: 10.1128/Iai.00026-20  0.451
2019 González JF, Kurtz J, Bauer DL, Hitt R, Fitch J, Wetzel A, La Perle K, White P, McLachlan J, Gunn JS. Establishment of Chronic Typhoid Infection in a Mouse Carriage Model Involves a Type 2 Immune Shift and T and B Cell Recruitment to the Gallbladder. Mbio. 10. PMID 31575775 DOI: 10.1128/mBio.02262-19  0.41
2019 Baker SM, McLachlan JB, Morici LA. Immunological considerations in the development of vaccines. Human Vaccines & Immunotherapeutics. PMID 31368828 DOI: 10.1080/21645515.2019.1650999  0.491
2019 Baker SM, Pociask D, Clements JD, McLachlan JB, Morici LA. Intradermal vaccination with a Pseudomonas aeruginosa vaccine adjuvanted with a mutant bacterial ADP-ribosylating enterotoxin protects against acute pneumonia. Vaccine. PMID 30638799 DOI: 10.1016/J.Vaccine.2018.12.053  0.541
2017 Frederick DR, Goggins JA, Sabbagh LM, Freytag LC, Clements JD, McLachlan JB. Adjuvant selection regulates gut migration and phenotypic diversity of antigen-specific CD4 T cells following parenteral immunization. Mucosal Immunology. 11: 549-561. PMID 28792004 DOI: 10.1038/Mi.2017.70  0.61
2017 Kurtz JR, Goggins JA, McLachlan JB. Salmonella infection: Interplay between the bacteria and host immune system. Immunology Letters. PMID 28720334 DOI: 10.1016/j.imlet.2017.07.006  0.454
2014 Dutta NK, McLachlan J, Mehra S, Kaushal D. Humoral and lung immune responses to Mycobacterium tuberculosis infection in a primate model of protection (.) Trials in Vaccinology. 3: 47-51. PMID 25197327 DOI: 10.1016/J.Trivac.2014.02.001  0.428
2014 Kurtz JR, Petersen HE, Frederick DR, Morici LA, McLachlan JB. Vaccination with a single CD4 T cell peptide epitope from a Salmonella type III-secreted effector protein provides protection against lethal infection. Infection and Immunity. 82: 2424-33. PMID 24686055 DOI: 10.1128/Iai.00052-14  0.469
2013 Nelson RW, McLachlan JB, Kurtz JR, Jenkins MK. CD4+ T cell persistence and function after infection are maintained by low-level peptide:MHC class II presentation. Journal of Immunology (Baltimore, Md. : 1950). 190: 2828-34. PMID 23382562 DOI: 10.4049/Jimmunol.1202183  0.303
2012 Lee SJ, McLachlan JB, Kurtz JR, Fan D, Winter SE, Baumler AJ, Jenkins MK, McSorley SJ. Temporal expression of bacterial proteins instructs host CD4 T cell expansion and Th17 development. Plos Pathogens. 8: e1002499. PMID 22275869 DOI: 10.1371/Journal.Ppat.1002499  0.341
2011 Nieves W, Asakrah S, Qazi O, Brown KA, Kurtz J, Aucoin DP, McLachlan JB, Roy CJ, Morici LA. A naturally derived outer-membrane vesicle vaccine protects against lethal pulmonary Burkholderia pseudomallei infection. Vaccine. 29: 8381-9. PMID 21871517 DOI: 10.1016/J.Vaccine.2011.08.058  0.554
2010 Jenkins MK, Chu HH, McLachlan JB, Moon JJ. On the composition of the preimmune repertoire of T cells specific for Peptide-major histocompatibility complex ligands. Annual Review of Immunology. 28: 275-94. PMID 20307209 DOI: 10.1146/Annurev-Immunol-030409-101253  0.304
2009 Shelburne CP, Nakano H, St John AL, Chan C, McLachlan JB, Gunn MD, Staats HF, Abraham SN. Mast cells augment adaptive immunity by orchestrating dendritic cell trafficking through infected tissues. Cell Host & Microbe. 6: 331-42. PMID 19837373 DOI: 10.1016/J.Chom.2009.09.004  0.722
2009 Moon JJ, Chu HH, Hataye J, Pagán AJ, Pepper M, McLachlan JB, Zell T, Jenkins MK. Tracking epitope-specific T cells. Nature Protocols. 4: 565-81. PMID 19373228 DOI: 10.1038/Nprot.2009.9  0.329
2009 Ertelt JM, Rowe JH, Johanns TM, Lai JC, McLachlan JB, Way SS. Selective priming and expansion of antigen-specific Foxp3- CD4+ T cells during Listeria monocytogenes infection. Journal of Immunology (Baltimore, Md. : 1950). 182: 3032-8. PMID 19234199 DOI: 10.4049/Jimmunol.0803402  0.302
2009 McLachlan JB, Catron DM, Moon JJ, Jenkins MK. Dendritic cell antigen presentation drives simultaneous cytokine production by effector and regulatory T cells in inflamed skin. Immunity. 30: 277-88. PMID 19200757 DOI: 10.1016/J.Immuni.2008.11.013  0.452
2008 McLachlan JB, Shelburne CP, Hart JP, Pizzo SV, Goyal R, Brooking-Dixon R, Staats HF, Abraham SN. Mast cell activators: a new class of highly effective vaccine adjuvants. Nature Medicine. 14: 536-41. PMID 18425129 DOI: 10.1038/Nm1757  0.322
2007 McLachlan JB, Jenkins MK. Migration and accumulation of effector CD4+ T cells in nonlymphoid tissues. Proceedings of the American Thoracic Society. 4: 439-42. PMID 17684285 DOI: 10.1513/pats.200606-137MS  0.36
2006 Shelburne CP, McLachlan JB, Abraham SN. In vivo models for studying mast cell-dependent responses to bacterial infection. Methods in Molecular Biology (Clifton, N.J.). 315: 363-81. PMID 16110170 DOI: 10.1385/1-59259-967-2:363  0.642
2003 McLachlan JB, Hart JP, Pizzo SV, Shelburne CP, Staats HF, Gunn MD, Abraham SN. Mast cell-derived tumor necrosis factor induces hypertrophy of draining lymph nodes during infection. Nature Immunology. 4: 1199-205. PMID 14595438 DOI: 10.1038/Ni1005  0.647
2001 McLachlan JB, Abraham SN. Studies of the multifaceted mast cell response to bacteria. Current Opinion in Microbiology. 4: 260-6. PMID 11378476 DOI: 10.1016/S1369-5274(00)00200-9  0.663
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