Year |
Citation |
Score |
2023 |
Meng X, Dang HQ, Kapler GM. Developmentally Programmed Switches in DNA Replication: Gene Amplification and Genome-Wide Endoreplication in . Microorganisms. 11. PMID 36838456 DOI: 10.3390/microorganisms11020491 |
0.635 |
|
2021 |
Lee SR, Pollard DA, Galati DF, Kelly ML, Miller B, Mong C, Morris MN, Roberts-Nygren K, Kapler GM, Zinkgraf M, Dang HQ, Branham E, Tessier E, Yoshiyama C, Sasser J, et al. Disruption of a ∼23-24 nucleotide small RNA pathway elevates DNA damage responses in . Molecular Biology of the Cell. mbcE20100631. PMID 34010017 DOI: 10.1091/mbc.E20-10-0631 |
0.444 |
|
2020 |
Zhao Q, Zhang L, Hai B, Wang J, Baetge CL, Deveau MA, Kapler GM, Feng JQ, Liu F. Transient activation of the Hedgehog-Gli pathway rescues radiotherapy-induced dry mouth via recovering salivary gland resident macrophages. Cancer Research. PMID 32998998 DOI: 10.1158/0008-5472.CAN-20-0503 |
0.622 |
|
2017 |
Feng L, Wang G, Hamilton EP, Xiong J, Yan G, Chen K, Chen X, Dui W, Plemens A, Khadr L, Dhanekula A, Juma M, Dang HQ, Kapler GM, Orias E, et al. A germline-limited piggyBac transposase gene is required for precise excision in Tetrahymena genome rearrangement. Nucleic Acids Research. 45: 9481-9502. PMID 28934495 DOI: 10.1093/Nar/Gkx652 |
0.3 |
|
2015 |
Sandoval PY, Lee PH, Meng X, Kapler GM. Checkpoint Activation of an Unconventional DNA Replication Program in Tetrahymena. Plos Genetics. 11: e1005405. PMID 26218270 DOI: 10.1371/journal.pgen.1005405 |
0.651 |
|
2015 |
Lee PH, Meng X, Kapler GM. Developmental regulation of the Tetrahymena thermophila origin recognition complex. Plos Genetics. 11: e1004875. PMID 25569357 DOI: 10.1371/journal.pgen.1004875 |
0.657 |
|
2013 |
Gao S, Xiong J, Zhang C, Berquist BR, Yang R, Zhao M, Molascon AJ, Kwiatkowski SY, Yuan D, Qin Z, Wen J, Kapler GM, Andrews PC, Miao W, Liu Y. Impaired replication elongation in Tetrahymena mutants deficient in histone H3 Lys 27 monomethylation. Genes & Development. 27: 1662-79. PMID 23884606 DOI: 10.1101/Gad.218966.113 |
0.361 |
|
2009 |
Donti TR, Datta S, Sandoval PY, Kapler GM. Differential targeting of Tetrahymena ORC to ribosomal DNA and non-rDNA replication origins. The Embo Journal. 28: 223-33. PMID 19153611 DOI: 10.1038/emboj.2008.282 |
0.408 |
|
2007 |
Mohammad MM, Donti TR, Sebastian Yakisich J, Smith AG, Kapler GM. Tetrahymena ORC contains a ribosomal RNA fragment that participates in rDNA origin recognition. The Embo Journal. 26: 5048-60. PMID 18007594 DOI: 10.1038/sj.emboj.7601919 |
0.324 |
|
2006 |
Yakisich JS, Sandoval PY, Morrison TL, Kapler GM. TIF1 activates the intra-S-phase checkpoint response in the diploid micronucleus and amitotic polyploid macronucleus of Tetrahymena. Molecular Biology of the Cell. 17: 5185-97. PMID 17005912 DOI: 10.1091/Mbc.E06-05-0469 |
0.666 |
|
2006 |
Yakisich JS, Kapler GM. Deletion of the Tetrahymena thermophila rDNA replication fork barrier region disrupts macronuclear rDNA excision and creates a fragile site in the micronuclear genome Nucleic Acids Research. 34: 620-634. PMID 16449202 DOI: 10.1093/nar/gkj466 |
0.339 |
|
2005 |
Morrison TL, Yakisich JS, Cassidy-Hanley D, Kapler GM. TIF1 Represses rDNA replication initiation, but promotes normal S phase progression and chromosome transmission in Tetrahymena. Molecular Biology of the Cell. 16: 2624-35. PMID 15772155 DOI: 10.1091/Mbc.E05-02-0107 |
0.676 |
|
2004 |
Smith JJ, Yakisich JS, Kapler GM, Cole ES, Romero DP. A beta-tubulin mutation selectively uncouples nuclear division and cytokinesis in Tetrahymena thermophila. Eukaryotic Cell. 3: 1217-26. PMID 15470250 DOI: 10.1128/Ec.3.5.1217-1226.2004 |
0.608 |
|
2003 |
Mohammad M, York RD, Hommel J, Kapler GM. Characterization of a novel origin recognition complex-like complex: implications for DNA recognition, cell cycle control, and locus-specific gene amplification. Molecular and Cellular Biology. 23: 5005-17. PMID 12832485 DOI: 10.1128/Mcb.23.14.5005-5017.2003 |
0.47 |
|
2002 |
Turkewitz AP, Orias E, Kapler G. Functional genomics: the coming of age for Tetrahymena thermophila. Trends in Genetics : Tig. 18: 35-40. PMID 11750699 DOI: 10.1016/S0168-9525(01)02560-4 |
0.367 |
|
2001 |
Saha S, Nicholson A, Kapler GM. Cloning and biochemical analysis of the Tetrahymena origin binding protein TIF1: Competitive DNA binding in vitro and in vivo to critical rDNA replication determinants Journal of Biological Chemistry. 276: 45417-45426. PMID 11577092 DOI: 10.1074/jbc.M106162200 |
0.357 |
|
2000 |
Mohammad M, Saha S, Kapler GM. Three different proteins recognize a multifunctional determinant that controls replication initiation, fork arrest and transcription in Tetrahymena Nucleic Acids Research. 28: 843-851. PMID 10637338 |
0.362 |
|
2000 |
Saha S, Kapler GM. Allele-specific protein-DNA interactions between the single-stranded DNA-binding protein, ssA-TIBF, and DNA replication determinants in Tetrahymena Journal of Molecular Biology. 295: 423-439. PMID 10623536 DOI: 10.1006/jmbi.1999.3365 |
0.346 |
|
2000 |
Gaertig J, Kapler G. Transient and stable DNA transformation of Tetrahymena thermophila by electroporation Methods in Cell Biology. 485-500. PMID 10503213 DOI: 10.1016/S0091-679X(08)61552-6 |
0.422 |
|
1999 |
Hargrove BW, Bhattacharyya A, Domitrovich AM, Kapler GM, Kirk K, Shippen DE, Kunkel GR. Identification of an essential proximal sequence element in the promoter of the telomerase RNA gene of Tetrahymena thermophila. Nucleic Acids Research. 27: 4269-75. PMID 10518620 DOI: 10.1093/Nar/27.21.4269 |
0.626 |
|
1997 |
Zhang Z, Macalpine DM, Kapler GM. Developmental regulation of DNA replication: Replication fork barriers and programmed gene amplification in Tetrahymena thermophila Molecular and Cellular Biology. 17: 6147-6156. PMID 9315675 DOI: 10.1128/Mcb.17.10.6147 |
0.434 |
|
1997 |
MacAlpine DM, Zhang Z, Kapler GM. Type I elements mediate replication fork pausing at conserved upstream sites in the Tetrahymena thermophila ribosomal DNA minichromosome Molecular and Cellular Biology. 17: 4517-4525. PMID 9234709 DOI: 10.1128/Mcb.17.8.4517 |
0.411 |
|
1994 |
Kapler GM, Blackburn EH. A weak germ-line excision mutation blocks developmentally controlled amplification of the rDNA minichromosome of Tetrahymena thermophila Genes and Development. 8: 84-95. PMID 8288130 DOI: 10.1101/Gad.8.1.84 |
0.491 |
|
1994 |
Kapler GM, Orias E, Blackburn EH. Tetrahymena thermophila mutants defective in the developmentally programmed maturation and maintenance of the rDNA minichromosome Genetics. 137: 455-466. PMID 8070657 |
0.543 |
|
1993 |
Kapler GM. Developmentally regulated processing and replication of the Tetrahymena rDNA minichromosome Current Opinion in Genetics and Development. 3: 730-735. PMID 8274855 DOI: 10.1016/S0959-437X(05)80091-7 |
0.32 |
|
1990 |
Kapler GM, Coburn CM, Beverley SM. Stable transfection of the human parasite Leishmania major delineates a 30-kilobase region sufficient for extrachromosomal replication and expression Molecular and Cellular Biology. 10: 1084-1094. PMID 2304458 DOI: 10.1128/Mcb.10.3.1084 |
0.585 |
|
1990 |
Kapler GM, Zhang K, Beverley SM. Nuclease mapping and DNA sequence analysis of transcripts from the dihydrofolate reductase-thymidylate synthase (R) region of Leishmania major Nucleic Acids Research. 18: 6399-6408. PMID 2243782 DOI: 10.1093/Nar/18.21.6399 |
0.552 |
|
1989 |
Kapler GM, Beverley SM. Transcriptional mapping of the amplified region encoding the dihydrofolate reductase-thymidylate synthase of Leishmania major reveals a high density of transcripts, including overlapping and antisense RNAs Molecular and Cellular Biology. 9: 3959-3972. PMID 2476667 DOI: 10.1128/Mcb.9.9.3959 |
0.503 |
|
1987 |
Kapler GM, Zhang K, Beverley SM. Sequence and S1 nuclease mapping of the 5′ region of the dihydrofolate reductasethymidylate synthase gene of Leishmania major Nucleic Acids Research. 15: 3369-3383. PMID 3554143 DOI: 10.1093/Nar/15.8.3369 |
0.519 |
|
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