| Year |
Citation |
Score |
| 2023 |
Schaenzer AJ, Rodriguez Hernandez A, Tsai K, Hobson C, Fujimori DG, Wright GD. Angucyclinones rescue PhLOPS antibiotic activity by inhibiting Cfr-dependent antibiotic resistance. Mbio. 14: e0179123. PMID 38014974 DOI: 10.1128/mbio.01791-23 |
0.527 |
|
| 2023 |
Sarah L, Fujimori DG. Recent developments in catalysis and inhibition of the Jumonji histone demethylases. Current Opinion in Structural Biology. 83: 102707. PMID 37832177 DOI: 10.1016/j.sbi.2023.102707 |
0.329 |
|
| 2022 |
Tsai K, Stojković V, Lee DJ, Young ID, Szal T, Klepacki D, Vázquez-Laslop N, Mankin AS, Fraser JS, Fujimori DG. Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics. Nature Structural & Molecular Biology. 29: 162-171. PMID 35165456 DOI: 10.1038/s41594-022-00723-9 |
0.718 |
|
| 2022 |
Tsai K, Stojković V, Noda-Garcia L, Young ID, Myasnikov AG, Kleinman J, Palla A, Floor SN, Frost A, Fraser JS, Tawfik DS, Fujimori DG. Directed evolution of the rRNA methylating enzyme Cfr reveals molecular basis of antibiotic resistance. Elife. 11. PMID 35015630 DOI: 10.7554/eLife.70017 |
0.748 |
|
| 2021 |
Stojković V, Weinberg DE, Fujimori DG. miCLIP-MaPseq Identifies Substrates of Radical SAM RNA-Methylating Enzyme Using Mechanistic Cross-Linking and Mismatch Profiling. Methods in Molecular Biology (Clifton, N.J.). 2298: 105-122. PMID 34085241 DOI: 10.1007/978-1-0716-1374-0_7 |
0.748 |
|
| 2020 |
Longbotham JE, Zhang MY, Fujimori DG. Domain cross-talk in regulation of histone modifications: Molecular mechanisms and targeting opportunities. Current Opinion in Chemical Biology. 57: 105-113. PMID 32758979 DOI: 10.1016/J.Cbpa.2020.06.001 |
0.376 |
|
| 2020 |
Petronikolou N, Longbotham JE, Fujimori DG. Dissecting contributions of catalytic and reader domains in regulation of histone demethylation. Methods in Enzymology. 639: 217-236. PMID 32475402 DOI: 10.1016/Bs.Mie.2020.04.015 |
0.369 |
|
| 2020 |
Stojković V, Myasnikov AG, Young ID, Frost A, Fraser JS, Fujimori DG. Assessment of the nucleotide modifications in the high-resolution cryo-electron microscopy structure of the Escherichia coli 50S subunit. Nucleic Acids Research. PMID 31989172 DOI: 10.1093/Nar/Gkaa037 |
0.721 |
|
| 2020 |
Petronikolou N, Longbotham JE, Fujimori DG. Extended Recognition of the Histone H3 Tail by Histone Demethylase KDM5A. Biochemistry. 59: 647-651. PMID 31985200 DOI: 10.1021/Acs.Biochem.9B01036 |
0.397 |
|
| 2019 |
Stojković V, Ulate MF, Hidalgo-Villeda F, Aguilar E, Monge-Cascante C, Pizarro-Guajardo M, Tsai K, Tzoc E, Camorlinga M, Paredes-Sabja D, Quesada-Gómez C, Fujimori DG, Rodríguez C. cfr(B), (C), and a new -like gene, (E), in strains recovered across Latin America. Antimicrobial Agents and Chemotherapy. PMID 31685464 DOI: 10.1128/Aac.01074-19 |
0.715 |
|
| 2019 |
Longbotham JE, Chio CM, Dharmarajan V, Trnka MJ, Torres IO, Goswami D, Ruiz K, Burlingame AL, Griffin PR, Fujimori DG. Histone H3 binding to the PHD1 domain of histone demethylase KDM5A enables active site remodeling. Nature Communications. 10: 94. PMID 30626866 DOI: 10.1038/S41467-018-07829-Z |
0.33 |
|
| 2018 |
Stojković V, Chu T, Therizols G, Weinberg DE, Fujimori DG. miCLIP-MaPseq, a substrate identification approach for radical SAM RNA methylating enzymes. Journal of the American Chemical Society. PMID 29782154 DOI: 10.1021/Jacs.8B02618 |
0.756 |
|
| 2017 |
Stojković V, Fujimori DG. Mutations in RNA methylating enzymes in disease. Current Opinion in Chemical Biology. 41: 20-27. PMID 29059606 DOI: 10.1016/J.Cbpa.2017.10.002 |
0.752 |
|
| 2016 |
Fitzsimmons CM, Fujimori DG. Determinants of tRNA Recognition by the Radical SAM Enzyme RlmN. Plos One. 11: e0167298. PMID 27902775 DOI: 10.1371/Journal.Pone.0167298 |
0.787 |
|
| 2016 |
Stojković V, Noda-Garcia L, Tawfik DS, Fujimori DG. Antibiotic resistance evolved via inactivation of a ribosomal RNA methylating enzyme. Nucleic Acids Research. PMID 27496281 DOI: 10.1093/Nar/Gkw699 |
0.765 |
|
| 2016 |
Liu YC, Fujimori DG, Weissman JS. Htm1p-Pdi1p is a folding-sensitive mannosidase that marks N-glycoproteins for ER-associated protein degradation. Proceedings of the National Academy of Sciences of the United States of America. PMID 27357682 DOI: 10.1073/Pnas.1608795113 |
0.317 |
|
| 2016 |
Pack LR, Yamamoto KR, Fujimori DG. Opposing Chromatin Signals Direct and Regulate the Demethylase Activity of KDM4C. The Journal of Biological Chemistry. PMID 26747609 DOI: 10.1074/Jbc.M115.696864 |
0.378 |
|
| 2015 |
Korczynska M, Le DD, Younger N, Gregori-Puigjané E, Tumber A, Krojer T, Velupillai S, Gileadi C, Nowak RP, Iwasa E, Pollock SB, Ortiz Torres I, Oppermann U, Shoichet BK, Fujimori DG. Docking and Linking of Fragments To Discover Jumonji Histone Demethylase Inhibitors. Journal of Medicinal Chemistry. PMID 26699912 DOI: 10.1021/Acs.Jmedchem.5B01527 |
0.578 |
|
| 2015 |
Torres IO, Fujimori DG. Functional coupling between writers, erasers and readers of histone and DNA methylation. Current Opinion in Structural Biology. 35: 68-75. PMID 26496625 DOI: 10.1016/J.Sbi.2015.09.007 |
0.428 |
|
| 2015 |
Lu J, Trnka MJ, Roh SH, Robinson PJ, Shiau C, Fujimori DG, Chiu W, Burlingame AL, Guan S. Improved Peak Detection and Deconvolution of Native Electrospray Mass Spectra from Large Protein Complexes. Journal of the American Society For Mass Spectrometry. PMID 26323614 DOI: 10.1007/S13361-015-1235-6 |
0.573 |
|
| 2015 |
Stojković V, Fujimori DG. Radical SAM-Mediated Methylation of Ribosomal RNA. Methods in Enzymology. 560: 355-76. PMID 26253978 DOI: 10.1016/Bs.Mie.2015.03.002 |
0.738 |
|
| 2015 |
Torres IO, Kuchenbecker KM, Nnadi CI, Fletterick RJ, Kelly MJ, Fujimori DG. Histone demethylase KDM5A is regulated by its reader domain through a positive-feedback mechanism. Nature Communications. 6: 6204. PMID 25686748 DOI: 10.1038/Ncomms7204 |
0.381 |
|
| 2015 |
Dumesic PA, Homer CM, Moresco JJ, Pack LR, Shanle EK, Coyle SM, Strahl BD, Fujimori DG, Yates JR, Madhani HD. Product binding enforces the genomic specificity of a yeast polycomb repressive complex. Cell. 160: 204-18. PMID 25533783 DOI: 10.1016/J.Cell.2014.11.039 |
0.394 |
|
| 2013 |
Fujimori DG. Radical SAM-mediated methylation reactions Current Opinion in Chemical Biology. 17: 597-604. PMID 23835516 DOI: 10.1016/J.Cbpa.2013.05.032 |
0.5 |
|
| 2013 |
Shiau C, Trnka MJ, Bozicevic A, Ortiz Torres I, Al-Sady B, Burlingame AL, Narlikar GJ, Fujimori DG. Reconstitution of nucleosome demethylation and catalytic properties of a Jumonji histone demethylase. Chemistry & Biology. 20: 494-9. PMID 23601638 DOI: 10.1016/J.Chembiol.2013.03.008 |
0.643 |
|
| 2013 |
Le DD, Cortesi AT, Myers SA, Burlingame AL, Fujimori DG. Site-specific and regiospecific installation of methylarginine analogues into recombinant histones and insights into effector protein binding. Journal of the American Chemical Society. 135: 2879-82. PMID 23398247 DOI: 10.1021/Ja3108214 |
0.628 |
|
| 2012 |
McCusker KP, Medzihradszky KF, Shiver AL, Nichols RJ, Yan F, Maltby DA, Gross CA, Fujimori DG. Covalent intermediate in the catalytic mechanism of the radical S-adenosyl-L-methionine methyl synthase RlmN trapped by mutagenesis. Journal of the American Chemical Society. 134: 18074-81. PMID 23088750 DOI: 10.1021/Ja307855D |
0.768 |
|
| 2012 |
Le DD, Fujimori DG. Protein and nucleic acid methylating enzymes: mechanisms and regulation. Current Opinion in Chemical Biology. 16: 507-15. PMID 23085277 DOI: 10.1016/J.Cbpa.2012.09.014 |
0.66 |
|
| 2012 |
McCusker KP, Fujimori DG. The chemistry of peptidyltransferase center-targeted antibiotics: enzymatic resistance and approaches to countering resistance. Acs Chemical Biology. 7: 64-72. PMID 22208312 DOI: 10.1021/Cb200418F |
0.716 |
|
| 2011 |
Yan F, Fujimori DG. RNA methylation by Radical SAM enzymes RlmN and Cfr proceeds via methylene transfer and hydride shift Proceedings of the National Academy of Sciences of the United States of America. 108: 3930-3934. PMID 21368151 DOI: 10.1073/Pnas.1017781108 |
0.47 |
|
| 2010 |
Yan F, LaMarre JM, Röhrich R, Wiesner J, Jomaa H, Mankin AS, Fujimori DG. RlmN and Cfr are radical SAM enzymes involved in methylation of ribosomal RNA. Journal of the American Chemical Society. 132: 3953-64. PMID 20184321 DOI: 10.1021/Ja910850Y |
0.583 |
|
| 2010 |
Fujimori DG. A novel enzymatic rearrangement Chemistry and Biology. 17: 1269-1270. DOI: 10.1016/J.Chembiol.2010.12.003 |
0.319 |
|
| 2009 |
Wong C, Fujimori DG, Walsh CT, Drennan CL. Structural analysis of an open active site conformation of nonheme iron halogenase CytC3. Journal of the American Chemical Society. 131: 4872-9. PMID 19281171 DOI: 10.1021/Ja8097355 |
0.479 |
|
| 2008 |
Neumann CS, Fujimori DG, Walsh CT. Halogenation strategies in natural product biosynthesis. Chemistry & Biology. 15: 99-109. PMID 18291314 DOI: 10.1016/J.Chembiol.2008.01.006 |
0.426 |
|
| 2007 |
Neidig ML, Brown CD, Light KM, Fujimori DG, Nolan EM, Price JC, Barr EW, Bollinger JM, Krebs C, Walsh CT, Solomon EI. CD and MCD of CytC3 and taurine dioxygenase: role of the facial triad in alpha-KG-dependent oxygenases. Journal of the American Chemical Society. 129: 14224-31. PMID 17967013 DOI: 10.1021/Ja074557R |
0.695 |
|
| 2007 |
Fujimori DG, Hrvatin S, Neumann CS, Strieker M, Marahiel MA, Walsh CT. Cloning and characterization of the biosynthetic gene cluster for kutznerides. Proceedings of the National Academy of Sciences of the United States of America. 104: 16498-503. PMID 17940045 DOI: 10.1073/Pnas.0708242104 |
0.471 |
|
| 2007 |
Fujimori DG, Barr EW, Matthews ML, Koch GM, Yonce JR, Walsh CT, Bollinger JM, Krebs C, Riggs-Gelasco PJ. Spectroscopic evidence for a high-spin Br-Fe(IV)-oxo intermediate in the alpha-ketoglutarate-dependent halogenase CytC3 from Streptomyces. Journal of the American Chemical Society. 129: 13408-9. PMID 17939667 DOI: 10.1021/Ja076454E |
0.582 |
|
| 2007 |
Fujimori DG, Walsh CT. What's new in enzymatic halogenations. Current Opinion in Chemical Biology. 11: 553-60. PMID 17881282 DOI: 10.1016/J.Cbpa.2007.08.002 |
0.402 |
|
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