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Alexandros Tzatsos, Ph.D. - Publications

Affiliations: 
2006 Boston University, Boston, MA, United States 
Area:
Molecular Biology
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17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Sun J, Cai X, Yung MM, Zhou W, Li J, Zhang Y, Li Z, Liu SS, Cheung ANY, Ngan HYS, Li Y, Dai Z, Kai Y, Tzatsos A, Peng W, et al. miR-137 mediates the functional link between c-Myc and EZH2 that regulates cisplatin resistance in ovarian cancer. Oncogene. PMID 30166592 DOI: 10.1038/S41388-018-0459-X  0.301
2018 Meng Y, Chen CW, Yung MMH, Sun W, Sun J, Li Z, Li J, Li Z, Zhou W, Liu SS, Cheung ANY, Ngan HYS, Braisted JC, Kai Y, Peng W, ... Tzatsos A, et al. DUOXA1-mediated ROS production promotes cisplatin resistance by activating ATR-Chk1 pathway in ovarian cancer. Cancer Letters. PMID 29704517 DOI: 10.1016/J.Canlet.2018.04.029  0.328
2018 Andricovich J, Perkail S, Kai Y, Casasanta N, Peng W, Tzatsos A. Loss of KDM6A Activates Super-Enhancers to Induce Gender-Specific Squamous-like Pancreatic Cancer and Confers Sensitivity to BET Inhibitors. Cancer Cell. 33: 512-526.e8. PMID 29533787 DOI: 10.1016/J.Ccell.2018.02.003  0.311
2016 Andricovich J, Kai Y, Tzatsos A. Lysine-specific histone demethylases in normal and malignant hematopoiesis. Experimental Hematology. PMID 27208808 DOI: 10.1016/J.Exphem.2016.05.006  0.319
2016 Andricovich J, Kai Y, Peng W, Foudi A, Tzatsos A. Histone demethylase KDM2B regulates lineage commitment in normal and malignant hematopoiesis. The Journal of Clinical Investigation. 126: 905-20. PMID 26808549 DOI: 10.1172/Jci84014  0.37
2013 Gao T, Zhou D, Yang C, Singh T, Penzo-Méndez A, Maddipati R, Tzatsos A, Bardeesy N, Avruch J, Stanger BZ. Hippo signaling regulates differentiation and maintenance in the exocrine pancreas. Gastroenterology. 144: 1543-53, 1553.e1. PMID 23454691 DOI: 10.1053/J.Gastro.2013.02.037  0.427
2013 Tzatsos A, Paskaleva P, Ferrari F, Deshpande V, Stoykova S, Contino G, Wong KK, Lan F, Trojer P, Park PJ, Bardeesy N. KDM2B promotes pancreatic cancer via Polycomb-dependent and -independent transcriptional programs. The Journal of Clinical Investigation. 123: 727-39. PMID 23321669 DOI: 10.1172/Jci64535  0.387
2011 Tzatsos A, Paskaleva P, Lymperi S, Contino G, Stoykova S, Chen Z, Wong KK, Bardeesy N. Lysine-specific demethylase 2B (KDM2B)-let-7-enhancer of zester homolog 2 (EZH2) pathway regulates cell cycle progression and senescence in primary cells. The Journal of Biological Chemistry. 286: 33061-9. PMID 21757686 DOI: 10.1074/Jbc.M111.257667  0.379
2011 Corcoran RB, Contino G, Deshpande V, Tzatsos A, Conrad C, Benes CH, Levy DE, Settleman J, Engelman JA, Bardeesy N. STAT3 plays a critical role in KRAS-induced pancreatic tumorigenesis. Cancer Research. 71: 5020-9. PMID 21586612 DOI: 10.1158/0008-5472.Can-11-0908  0.41
2010 Gurumurthy S, Xie SZ, Alagesan B, Kim J, Yusuf RZ, Saez B, Tzatsos A, Ozsolak F, Milos P, Ferrari F, Park PJ, Shirihai OS, Scadden DT, Bardeesy N. The Lkb1 metabolic sensor maintains haematopoietic stem cell survival. Nature. 468: 659-63. PMID 21124451 DOI: 10.1038/Nature09572  0.379
2009 Tzatsos A. Raptor binds the SAIN (Shc and IRS-1 NPXY binding) domain of insulin receptor substrate-1 (IRS-1) and regulates the phosphorylation of IRS-1 at Ser-636/639 by mTOR. The Journal of Biological Chemistry. 284: 22525-34. PMID 19561084 DOI: 10.1074/Jbc.M109.027748  0.43
2009 Tzatsos A, Pfau R, Kampranis SC, Tsichlis PN. Ndy1/KDM2B immortalizes mouse embryonic fibroblasts by repressing the Ink4a/Arf locus. Proceedings of the National Academy of Sciences of the United States of America. 106: 2641-6. PMID 19202064 DOI: 10.1073/Pnas.0813139106  0.342
2008 Pfau R, Tzatsos A, Kampranis SC, Serebrennikova OB, Bear SE, Tsichlis PN. Members of a family of JmjC domain-containing oncoproteins immortalize embryonic fibroblasts via a JmjC domain-dependent process. Proceedings of the National Academy of Sciences of the United States of America. 105: 1907-12. PMID 18250326 DOI: 10.1073/Pnas.0711865105  0.358
2007 Tzatsos A, Tsichlis PN. Energy depletion inhibits phosphatidylinositol 3-kinase/Akt signaling and induces apoptosis via AMP-activated protein kinase-dependent phosphorylation of IRS-1 at Ser-794. The Journal of Biological Chemistry. 282: 18069-82. PMID 17459875 DOI: 10.1074/Jbc.M610101200  0.433
2007 Pfau R, Tzatsos A, Bear SE, Polytarchou C, Kampranis S, Van Etten RA, Tsichlis PN. A Chromatin-Associated Histone H3 Dementhylase Promotes the Immortalization of MEFs and the Cycling of HSC-Like Cells in Culture. Blood. 110: 96-96. DOI: 10.1182/Blood.V110.11.96.96  0.39
2006 Tzatsos A, Kandror KV. Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation. Molecular and Cellular Biology. 26: 63-76. PMID 16354680 DOI: 10.1128/Mcb.26.1.63-76.2006  0.598
2003 Roh C, Han J, Tzatsos A, Kandror KV. Nutrient-sensing mTOR-mediated pathway regulates leptin production in isolated rat adipocytes. American Journal of Physiology. Endocrinology and Metabolism. 284: E322-30. PMID 12388166 DOI: 10.1152/Ajpendo.00230.2002  0.492
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