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Sichen Shao, Ph.D. - Publications

Affiliations: 
2011 Johns Hopkins University, Baltimore, MD 
Area:
Cell Biology, Biochemistry
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33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Coelho JPL, Yip MCJ, Oltion K, Taunton J, Shao S. The eRF1 degrader SRI-41315 acts as a molecular glue at the ribosomal decoding center. Nature Chemical Biology. PMID 38172604 DOI: 10.1038/s41589-023-01521-0  0.352
2022 Shao S. Protein biosynthesis at the ER: finding the right accessories. Molecular Biology of the Cell. 34: pe1. PMID 36520029 DOI: 10.1091/mbc.E21-09-0451  0.354
2022 McKenna MJ, Adams BM, Chu V, Paulo JA, Shao S. ATP13A1 prevents ERAD of folding-competent mislocalized and misoriented proteins. Molecular Cell. PMID 36283413 DOI: 10.1016/j.molcel.2022.09.035  0.383
2022 McKenna MJ, Shao S. The Endoplasmic Reticulum and the Fidelity of Nascent Protein Localization. Cold Spring Harbor Perspectives in Biology. PMID 36041782 DOI: 10.1101/cshperspect.a041249  0.377
2021 Keszei AFA, Yip MCJ, Hsieh TC, Shao S. Structural insights into metazoan pretargeting GET complexes. Nature Structural & Molecular Biology. 28: 1029-1037. PMID 34887561 DOI: 10.1038/s41594-021-00690-7  0.341
2021 Chu V, Feng Q, Lim Y, Shao S. Selective destabilization of polypeptides synthesized from NMD-targeted transcripts. Molecular Biology of the Cell. mbcE21080382. PMID 34586879 DOI: 10.1091/mbc.E21-08-0382  0.358
2021 Yip MCJ, Shao S. Detecting and Rescuing Stalled Ribosomes. Trends in Biochemical Sciences. PMID 33966939 DOI: 10.1016/j.tibs.2021.03.008  0.357
2020 McKenna MJ, Sim SI, Ordureau A, Wei L, Harper JW, Shao S, Park E. The endoplasmic reticulum P5A-ATPase is a transmembrane helix dislocase. Science (New York, N.Y.). 369. PMID 32973005 DOI: 10.1126/science.abc5809  0.314
2020 Morehouse BR, Govande AA, Millman A, Keszei AFA, Lowey B, Ofir G, Shao S, Sorek R, Kranzusch PJ. STING cyclic dinucleotide sensing originated in bacteria. Nature. PMID 32877915 DOI: 10.1038/S41586-020-2719-5  0.355
2020 Lowey B, Whiteley AT, Keszei AFA, Morehouse BR, Mathews IT, Antine SP, Cabrera VJ, Kashin D, Niemann P, Jain M, Schwede F, Mekalanos JJ, Shao S, Lee ASY, Kranzusch PJ. CBASS Immunity Uses CARF-Related Effectors to Sense 3'-5'- and 2'-5'-Linked Cyclic Oligonucleotide Signals and Protect Bacteria from Phage Infection. Cell. PMID 32544385 DOI: 10.1016/J.Cell.2020.05.019  0.328
2020 Yip MCJ, Savickas S, Gygi SP, Shao S. ELAC1 Repairs tRNAs Cleaved during Ribosome-Associated Quality Control. Cell Reports. 30: 2106-2114.e5. PMID 32075755 DOI: 10.1016/J.Celrep.2020.01.082  0.411
2019 Chandrasekaran V, Juszkiewicz S, Choi J, Puglisi JD, Brown A, Shao S, Ramakrishnan V, Hegde RS. Mechanism of ribosome stalling during translation of a poly(A) tail. Nature Structural & Molecular Biology. PMID 31768042 DOI: 10.1038/S41594-019-0331-X  0.587
2019 Lin Z, Gasic I, Chandrasekaran V, Peters N, Shao S, Mitchison TJ, Hegde RS. TTC5 mediates autoregulation of tubulin via mRNA degradation. Science (New York, N.Y.). PMID 31727855 DOI: 10.1126/Science.Aaz4352  0.603
2019 Yip MCJ, Keszei AFA, Feng Q, Chu V, McKenna MJ, Shao S. Mechanism for recycling tRNAs on stalled ribosomes. Nature Structural & Molecular Biology. PMID 31011209 DOI: 10.1038/S41594-019-0211-4  0.45
2019 Inglis AJ, Masson GR, Shao S, Perisic O, McLaughlin SH, Hegde RS, Williams RL. Activation of GCN2 by the ribosomal P-stalk. Proceedings of the National Academy of Sciences of the United States of America. PMID 30804176 DOI: 10.1073/Pnas.1813352116  0.559
2018 Chitwood PJ, Juszkiewicz S, Guna A, Shao S, Hegde RS. EMC Is Required to Initiate Accurate Membrane Protein Topogenesis. Cell. PMID 30415835 DOI: 10.1016/J.Cell.2018.10.009  0.603
2018 Brown A, Baird MR, Yip MC, Murray J, Shao S. Structures of translationally inactive mammalian ribosomes. Elife. 7. PMID 30355441 DOI: 10.7554/Elife.40486  0.43
2017 Feng Q, Shao S. In vitro reconstitution of translational arrest pathways. Methods (San Diego, Calif.). PMID 29277545 DOI: 10.1016/J.Ymeth.2017.12.018  0.478
2017 Erez Z, Sorek R, Shao S, Hegde RS, Schweppe DK, Chavez JD, Bruce JE, Mizrachi E, Verbeke L, Peer YVd, Marchal K, Myburg AA, Bennett JA, Klironomos J, Payne GF, et al. Principles of Systems Biology, No. 14: Sense Codon Reassignment Boosts Protein Chemistries Cell Systems. 4: 143-143. PMID 28231445 DOI: 10.1016/J.Cels.2017.02.004  0.329
2017 Shao S, Rodrigo-Brenni MC, Kivlen MH, Hegde RS. Mechanistic basis for a molecular triage reaction. Science (New York, N.Y.). 355: 298-302. PMID 28104892 DOI: 10.1126/Science.Aah6130  0.594
2017 Inglis AJ, Shao S, Masson GR, Perisic O, Hegde RS, Williams RL. Abstract A32: The role of the ribosome in GCN2's ability to sense amino acid deprivation and initiate the integrated stress response Cancer Research. 77. DOI: 10.1158/1538-7445.Transcontrol16-A32  0.546
2016 Shao S, Murray J, Brown A, Taunton J, Ramakrishnan V, Hegde RS. Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes. Cell. 167: 1229-1240.e15. PMID 27863242 DOI: 10.1016/J.Cell.2016.10.046  0.61
2016 Itakura E, Zavodszky E, Shao S, Wohlever ML, Keenan RJ, Hegde RS. Ubiquilins Chaperone and Triage Mitochondrial Membrane Proteins for Degradation. Molecular Cell. PMID 27345149 DOI: 10.1016/J.Molcel.2016.05.020  0.599
2015 Shao S, Hegde RS. Target Selection during Protein Quality Control. Trends in Biochemical Sciences. PMID 26628391 DOI: 10.1016/J.Tibs.2015.10.007  0.603
2015 Brown A, Shao S, Murray J, Hegde RS, Ramakrishnan V. Structural basis for stop codon recognition in eukaryotes. Nature. 524: 493-6. PMID 26245381 DOI: 10.1038/Nature14896  0.582
2015 von der Malsburg K, Shao S, Hegde RS. The ribosome quality control pathway can access nascent polypeptides stalled at the Sec61 translocon. Molecular Biology of the Cell. 26: 2168-80. PMID 25877867 DOI: 10.1091/Mbc.E15-01-0040  0.614
2015 Shao S, Brown A, Santhanam B, Hegde RS. Structure and assembly pathway of the ribosome quality control complex. Molecular Cell. 57: 433-44. PMID 25578875 DOI: 10.1016/J.Molcel.2014.12.015  0.608
2014 Shao S, Hegde RS. Cell Biology. Local synthesis and disposal. Science (New York, N.Y.). 346: 701-2. PMID 25378608 DOI: 10.1126/Science.1261602  0.576
2014 Shao S, Hegde RS. Reconstitution of a minimal ribosome-associated ubiquitination pathway with purified factors. Molecular Cell. 55: 880-90. PMID 25132172 DOI: 10.1016/J.Molcel.2014.07.006  0.626
2013 Shao S, von der Malsburg K, Hegde RS. Listerin-dependent nascent protein ubiquitination relies on ribosome subunit dissociation. Molecular Cell. 50: 637-48. PMID 23685075 DOI: 10.1016/J.Molcel.2013.04.015  0.633
2011 Shao S, Hegde RS. A calmodulin-dependent translocation pathway for small secretory proteins. Cell. 147: 1576-88. PMID 22196732 DOI: 10.1016/J.Cell.2011.11.048  0.612
2011 Shao S, Hegde RS. Membrane protein insertion at the endoplasmic reticulum. Annual Review of Cell and Developmental Biology. 27: 25-56. PMID 21801011 DOI: 10.1146/Annurev-Cellbio-092910-154125  0.607
2011 Shao S, Hegde RS. A flip turn for membrane protein insertion. Cell. 146: 13-5. PMID 21729778 DOI: 10.1016/J.Cell.2011.06.028  0.568
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