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Kathryn M. Appleton, Ph.D. - Publications

Affiliations: 
2014 Medical University of South Carolina, Charleston, SC, United States 
Area:
Pharmacology, Endocrinology Biology
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10 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Strungs E, Appleton K, Kwon J, Robinson K, Peterson Y, Luttrell L, Lee M. Application of Intramolecular FlAsH-BRET to the Classification Arrestin Activation Modes Protocol Exchange. DOI: 10.1038/Protex.2017.149  0.566
2016 Lee MH, Appleton KM, El-Shewy HM, Sorci-Thomas MG, Thomas MJ, Lopes-Virella MF, Luttrell LM, Hammad SM, Klein RL. S1P in HDL Promotes Interaction Between SR-BI and S1PR1 and Activates S1PR1-Mediated Biological Functions: Calcium Flux and S1PR1 Internalization. Journal of Lipid Research. PMID 27881715 DOI: 10.1194/Jlr.M070706  0.356
2016 Haak AJ, Appleton KM, Lisabeth EM, Misek S, Ji Y, Wade SM, Bell JL, Rockwell CE, Airik M, Krook MA, Larsen SD, Verhaegen ME, Lawlor ER, Neubig RR. Pharmacological inhibition of Myocardin-related transcription factor pathway blocks lung metastases of RhoC overexpressing melanoma. Molecular Cancer Therapeutics. PMID 27837031 DOI: 10.1158/1535-7163.Mct-16-0482  0.344
2016 Lee MH, Appleton KM, Strungs EG, Kwon JY, Morinelli TA, Peterson YK, Laporte SA, Luttrell LM. The conformational signature of β-arrestin2 predicts its trafficking and signalling functions. Nature. PMID 27007854 DOI: 10.1038/Nature17154  0.692
2014 Appleton KM, Bigham KJ, Lindsey CC, Hazard S, Lirjoni J, Parnham S, Hennig M, Peterson YK. Development of inhibitors of heterotrimeric Gαi subunits. Bioorganic & Medicinal Chemistry. 22: 3423-34. PMID 24818958 DOI: 10.1016/J.Bmc.2014.04.035  0.441
2014 Raymond JR, Appleton KM, Pierce JY, Peterson YK. Suppression of GNAI2 message in ovarian cancer. Journal of Ovarian Research. 7: 6. PMID 24423449 DOI: 10.1186/1757-2215-7-6  0.648
2013 Wilson PC, Lee MH, Appleton KM, El-Shewy HM, Morinelli TA, Peterson YK, Luttrell LM, Jaffa AA. The arrestin-selective angiotensin AT1 receptor agonist [Sar1,Ile4,Ile8]-AngII negatively regulates bradykinin B2 receptor signaling via AT1-B2 receptor heterodimers. The Journal of Biological Chemistry. 288: 18872-84. PMID 23661707 DOI: 10.1074/Jbc.M113.472381  0.639
2013 Appleton KM, Luttrell LM. Emergent biological properties of arrestin pathway-selective biased agonism. Journal of Receptor and Signal Transduction Research. 33: 153-61. PMID 23448506 DOI: 10.3109/10799893.2013.769004  0.522
2013 Appleton KM, Lee MH, Alele C, Alele C, Luttrell DK, Peterson YK, Morinelli TA, Luttrell LM. Biasing the parathyroid hormone receptor: relating in vitro ligand efficacy to in vivo biological activity. Methods in Enzymology. 522: 229-62. PMID 23374189 DOI: 10.1016/B978-0-12-407865-9.00013-3  0.68
2013 Leonard AP, Appleton KM, Luttrell LM, Peterson YK. A high-content, live-cell, and real-time approach to the quantitation of ligand-induced β-Arrestin2 and Class A/Class B GPCR mobilization. Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. 19: 150-70. PMID 23351552 DOI: 10.1017/S1431927612014067  0.656
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