Elliott Mufson - Publications

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205 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Moreno-Rodriguez M, Perez SE, Martinez-Gardeazabal J, Manuel I, Malek-Ahmadi M, Rodriguez-Puertas R, Mufson EJ. Frontal Cortex Lipid Alterations During the Onset of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 38578893 DOI: 10.3233/JAD-231485  0.371
2024 Aldecoa I, Barroeta I, Carroll SL, Fortea J, Gilmore A, Ginsberg SD, Guzman SJ, Hamlett ED, Head E, Perez SE, Potter H, Molina-Porcel L, Raha-Chowdhury R, Wisniewski T, Yong WH, ... ... Mufson EJ, et al. Down Syndrome Biobank Consortium: A perspective. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 38270275 DOI: 10.1002/alz.13692  0.332
2023 Gautier MK, Kelley CM, Lee SH, Alldred MJ, McDaid J, Mufson EJ, Stutzmann GE, Ginsberg SD. Maternal choline supplementation protects against age-associated cholinergic and GABAergic basal forebrain neuron degeneration in the Ts65Dn mouse model of down syndrome and Alzheimer's disease. Neurobiology of Disease. 106332. PMID 37890559 DOI: 10.1016/j.nbd.2023.106332  0.411
2023 Dubnov S, Yayon N, Yakov O, Bennett DA, Seshadri S, Mufson E, Tzur Y, Bennet ER, Greenberg D, Kuro-O M, Paldor I, Abraham CR, Soreq H. Knockout of the longevity gene Klotho perturbs aging- and Alzheimer's disease-linked brain microRNAs and tRNA fragments. Biorxiv : the Preprint Server For Biology. PMID 37745362 DOI: 10.1101/2023.09.10.557032  0.306
2023 Mi Z, Abrahamson EE, Ryu AY, Malek-Ahmadi M, Kofler JK, Fish KN, Sweet RA, Villemagne VL, Schneider JA, Mufson EJ, Ikonomovic MD. Vesicular Glutamate Transporter Changes in the Cortical Default Mode Network During the Clinical and Pathological Progression of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 37212097 DOI: 10.3233/JAD-221063  0.352
2023 Shulman D, Dubnov S, Zorbaz T, Madrer N, Paldor I, Bennett DA, Seshadri S, Mufson EJ, Greenberg DS, Loewenstein Y, Soreq H. Sex-specific declines in cholinergic-targeting tRNA fragments in the nucleus accumbens in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 37158312 DOI: 10.1002/alz.13095  0.363
2023 Mahady LJ, Perez SE, Malek-Ahmadi M, Mufson EJ. Oligomeric, phosphorylated, and truncated tau and spliceosome pathology within the entorhinal-hippocampal connectome across stages of Alzheimer's disease. The Journal of Comparative Neurology. PMID 36989381 DOI: 10.1002/cne.25466  0.368
2023 Shulman D, Dubnov S, Zorbaz T, Madrer N, Paldor I, Bennett DA, Seshadri S, Mufson EJ, Greenberg DS, Loewenstein Y, Soreq H. Sex-specific declines in cholinergic-targeting tRNA fragments in the nucleus accumbens in Alzheimer's disease. Biorxiv : the Preprint Server For Biology. PMID 36798311 DOI: 10.1101/2023.02.08.527612  0.411
2022 Utagawa EC, Moreno DG, Schafernak KT, Arva NC, Malek-Ahmadi MH, Mufson EJ, Perez SE. Neurogenesis and neuronal differentiation in the postnatal frontal cortex in Down syndrome. Acta Neuropathologica Communications. 10: 86. PMID 35676735 DOI: 10.1186/s40478-022-01385-w  0.315
2022 Bhatia K, Kindelin A, Nadeem M, Khan MB, Yin J, Fuentes A, Miller K, Turner GH, Preul MC, Ahmad AS, Mufson EJ, Waters MF, Ahmad S, Ducruet AF. Complement C3a Receptor (C3aR) Mediates Vascular Dysfunction, Hippocampal Pathology, and Cognitive Impairment in a Mouse Model of VCID. Translational Stroke Research. PMID 35258803 DOI: 10.1007/s12975-022-00993-x  0.329
2022 Wakeman DR, Weed MR, Perez SE, Cline EN, Viola KL, Wilcox KC, Moddrelle DS, Nisbett EZ, Kurian AM, Bell AF, Pike R, Jacobson PB, Klein WL, Mufson EJ, Lawrence MS, et al. Intrathecal amyloid-beta oligomer administration increases tau phosphorylation in the medial temporal lobe in the African green monkey: a nonhuman primate model of Alzheimer's disease. Neuropathology and Applied Neurobiology. PMID 35156715 DOI: 10.1111/nan.12800  0.357
2022 Beck JS, Madaj Z, Cheema CT, Kara B, Bennett DA, Schneider JA, Gordon MN, Ginsberg SD, Mufson EJ, Counts SE. Co-expression Network Analysis of Frontal Cortex during the Progression of Alzheimer's Disease. Cerebral Cortex (New York, N.Y. : 1991). PMID 35076713 DOI: 10.1093/cercor/bhac001  0.386
2021 Powers BE, Velazquez R, Strawderman MS, Ginsberg SD, Mufson EJ, Strupp BJ. Maternal Choline Supplementation as a Potential Therapy for Down Syndrome: Assessment of Effects Throughout the Lifespan. Frontiers in Aging Neuroscience. 13: 723046. PMID 34690739 DOI: 10.3389/fnagi.2021.723046  0.751
2021 Moreno DG, Utagawa EC, Arva NC, Schafernak KT, Mufson EJ, Perez SE. Postnatal Cytoarchitecture and Neurochemical Hippocampal Dysfunction in Down Syndrome. Journal of Clinical Medicine. 10. PMID 34362198 DOI: 10.3390/jcm10153414  0.343
2021 Mufson EJ, Kelley C, Perez SE. Chronic traumatic encephalopathy and the nucleus basalis of Meynert. Handbook of Clinical Neurology. 182: 9-29. PMID 34266614 DOI: 10.1016/B978-0-12-819973-2.00002-2  0.366
2021 Freire-Cobo C, Edler MK, Varghese M, Munger E, Laffey J, Raia S, In SS, Wicinski B, Medalla M, Perez SE, Mufson EJ, Erwin JM, Guevara EE, Sherwood CC, Luebke JI, et al. Comparative neuropathology in aging primates: A perspective. American Journal of Primatology. e23299. PMID 34255875 DOI: 10.1002/ajp.23299  0.355
2021 Miguel JC, Perez SE, Malek-Ahmadi M, Mufson EJ. Cerebellar Calcium-Binding Protein and Neurotrophin Receptor Defects in Down Syndrome and Alzheimer's Disease. Frontiers in Aging Neuroscience. 13: 645334. PMID 33776745 DOI: 10.3389/fnagi.2021.645334  0.389
2020 Mahady L, He B, Malek-Ahmadi M, Mufson EJ. Telomeric Alterations in the Default Mode Network during the Progression of Alzheimer's disease: Selective Vulnerability of the Precuneus. Neuropathology and Applied Neurobiology. PMID 33107640 DOI: 10.1111/nan.12672  0.343
2020 Edler MK, Munger EL, Meindl RS, Hopkins WD, Ely JJ, Erwin JM, Mufson EJ, Hof PR, Sherwood CC, Raghanti MA. Neuron loss associated with age but not Alzheimer's disease pathology in the chimpanzee brain. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 375: 20190619. PMID 32951541 DOI: 10.1098/Rstb.2019.0619  0.402
2020 Snyder HM, Bain LJ, Brickman AM, Carrillo MC, Esbensen AJ, Espinosa JM, Fernandez F, Fortea J, Hartley SL, Head E, Hendrix J, Kishnani PS, Lai F, Lao P, Lemere C, ... ... Mufson EJ, et al. Further understanding the connection between Alzheimer's disease and Down syndrome. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 32544310 DOI: 10.1002/Alz.12112  0.369
2020 He B, Perez SE, Lee SH, Ginsberg SD, Malek-Ahmadi M, Mufson EJ. Expression profiling of precuneus layer III cathepsin D-immunopositive pyramidal neurons in mild cognitive impairment and Alzheimer's disease: Evidence for neuronal signaling vulnerability. The Journal of Comparative Neurology. PMID 32323319 DOI: 10.1002/cne.24929  0.693
2020 Moreno-Rodriguez M, Perez SE, Nadeem M, Malek-Ahmadi M, Mufson EJ. Frontal cortex chitinase and pentraxin neuroinflammatory alterations during the progression of Alzheimer's disease. Journal of Neuroinflammation. 17: 58. PMID 32066474 DOI: 10.1186/S12974-020-1723-X  0.69
2020 Malek-Ahmadi M, Perez SE, Chen K, Mufson EJ. Braak Stage, Cerebral Amyloid Angiopathy, and Cognitive Decline in Early Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 31985469 DOI: 10.3233/Jad-191151  0.707
2020 Tanaka H, Homma H, Fujita K, Kondo K, Yamada S, Jin X, Waragai M, Ohtomo G, Iwata A, Tagawa K, Atsuta N, Katsuno M, Tomita N, Furukawa K, Saito Y, ... ... Mufson EJ, et al. YAP-dependent necrosis occurs in early stages of Alzheimer's disease and regulates mouse model pathology. Nature Communications. 11: 507. PMID 31980612 DOI: 10.1038/S41467-020-14353-6  0.441
2019 Abrahamson EE, Head E, Lott IT, Handen BL, Mufson EJ, Christian BT, Klunk WE, Ikonomovic MD. Neuropathological correlates of amyloid PET imaging in Down syndrome. Developmental Neurobiology. PMID 31379087 DOI: 10.1002/Dneu.22713  0.363
2019 Ginsberg SD, Malek-Ahmadi MH, Alldred MJ, Chen Y, Chen K, Chao MV, Counts SE, Mufson EJ. Brain-derived neurotrophic factor (BDNF) and TrkB hippocampal gene expression are putative predictors of neuritic plaque and neurofibrillary tangle pathology. Neurobiology of Disease. 104540. PMID 31349032 DOI: 10.1016/J.Nbd.2019.104540  0.648
2019 Mufson EJ, Counts SE, Ginsberg SD, Mahady L, Perez SE, Massa SM, Longo FM, Ikonomovic MD. Nerve Growth Factor Pathobiology During the Progression of Alzheimer's Disease. Frontiers in Neuroscience. 13: 533. PMID 31312116 DOI: 10.3389/fnins.2019.00533  0.36
2019 Kelley CM, Ginsberg SD, Alldred MJ, Strupp BJ, Mufson EJ. Maternal choline supplementation alters basal forebrain cholinergic neuron gene expression in the Ts65Dn mouse model of Down syndrome. Developmental Neurobiology. PMID 31120189 DOI: 10.1002/Dneu.22700  0.673
2019 Perez SE, Miguel JC, He B, Malek-Ahmadi M, Abrahamson EE, Ikonomovic MD, Lott I, Doran E, Alldred MJ, Ginsberg SD, Mufson EJ. Frontal cortex and striatal cellular and molecular pathobiology in individuals with Down syndrome with and without dementia. Acta Neuropathologica. PMID 30734106 DOI: 10.1007/S00401-019-01965-6  0.683
2018 Munger EL, Edler MK, Hopkins WD, Ely JJ, Erwin JM, Perl DP, Mufson EJ, Hof PR, Sherwood CC, Raghanti MA. Astrocytic changes with aging and Alzheimer's disease-type pathology in chimpanzees. The Journal of Comparative Neurology. PMID 30578640 DOI: 10.1002/Cne.24610  0.329
2018 Mahady L, Nadeem M, Malek-Ahmadi M, Chen K, Perez SE, Mufson EJ. HDAC2 dysregulation in the nucleus basalis of Meynert during the progression of Alzheimer's disease. Neuropathology and Applied Neurobiology. PMID 30252960 DOI: 10.1111/nan.12518  0.706
2018 Malek-Ahmadi M, Chen K, Perez SE, He A, Mufson EJ. Cognitive composite score association with Alzheimer's disease plaque and tangle pathology. Alzheimer's Research & Therapy. 10: 90. PMID 30205840 DOI: 10.1186/S13195-018-0401-Z  0.711
2018 Edler MK, Sherwood CC, Meindl RS, Munger E, Hopkins WD, Ely JJ, Erwin JM, Perl DP, Mufson EJ, Hof PR, Raghanti MA. Microglia changes associated to Alzheimer's disease pathology in aged chimpanzees. The Journal of Comparative Neurology. PMID 30069930 DOI: 10.1002/Cne.24484  0.354
2018 Tiernan CT, Ginsberg SD, He B, Ward SM, Guillozet-Bongaarts AL, Kanaan NM, Mufson EJ, Counts SE. Pretangle pathology within cholinergic nucleus basalis neurons coincides with neurotrophic and neurotransmitter receptor gene dysregulation during the progression of Alzheimer's disease. Neurobiology of Disease. PMID 29859871 DOI: 10.1016/J.Nbd.2018.05.021  0.359
2018 Mahady L, Nadeem M, Malek-Ahmadi M, Chen K, Perez SE, Mufson EJ. Frontal Cortex Epigenetic Dysregulation During the Progression of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. 62: 115-131. PMID 29439356 DOI: 10.3233/Jad-171032  0.724
2018 Tiernan CT, Mufson EJ, Kanaan NM, Counts SE. Tau Oligomer Pathology in Nucleus Basalis Neurons During the Progression of Alzheimer Disease. Journal of Neuropathology and Experimental Neurology. PMID 29378005 DOI: 10.1093/Jnen/Nlx120  0.44
2017 Malek-Ahmadi M, Lu S, Chan Y, Perez SE, Chen K, Mufson EJ. Static and Dynamic Cognitive Reserve Proxy Measures: Interactions with Alzheimer's Disease Neuropathology and Cognition. Journal of Alzheimer's Disease & Parkinsonism. 7. PMID 29423338 DOI: 10.4172/2161-0460.1000390  0.673
2017 Edler MK, Sherwood CC, Meindl RS, Hopkins WD, Ely JJ, Erwin JM, Mufson EJ, Hof PR, Raghanti MA. Aged chimpanzees exhibit pathologic hallmarks of Alzheimer's disease. Neurobiology of Aging. PMID 28888720 DOI: 10.1016/J.Neurobiolaging.2017.07.006  0.365
2017 Ginsberg SD, Malek-Ahmadi MH, Alldred MJ, Che S, Elarova I, Chen Y, Jeanneteau F, Kranz TM, Chao MV, Counts SE, Mufson EJ. Selective decline of neurotrophin and neurotrophin receptor genes within CA1 pyramidal neurons and hippocampus proper: Correlation with cognitive performance and neuropathology in mild cognitive impairment and Alzheimer's disease. Hippocampus. PMID 28888073 DOI: 10.1002/Hipo.22802  0.712
2017 Perez SE, Nadeem M, Malek-Ahmadi MH, He B, Mufson EJ. Frontal Cortex and Hippocampal γ-Secretase Activating Protein Levels in Prodromal Alzheimer Disease. Neuro-Degenerative Diseases. 17: 235-241. PMID 28743126 DOI: 10.1159/000477937  0.635
2017 Malek-Ahmadi M, Lu S, Chan Y, Perez SE, Chen K, Mufson EJ. Cognitive Domain Dispersion Association with Alzheimer's Disease Pathology. Journal of Alzheimer's Disease : Jad. PMID 28453479 DOI: 10.3233/Jad-161233  0.714
2017 Perez SE, Nadeem M, He B, Miguel JC, Malek-Ahmadi MH, Chen K, Mufson EJ. Neocortical and hippocampal TREM2 protein levels during the progression of Alzheimer's disease. Neurobiology of Aging. PMID 28365005 DOI: 10.1016/j.neurobiolaging.2017.02.012  0.708
2017 Mi Z, Abrahamson EE, Ryu AY, Fish KN, Sweet RA, Mufson EJ, Ikonomovic MD. Loss of precuneus dendritic spines immunopositive for spinophilin is related to cognitive impairment in early Alzheimer's disease. Neurobiology of Aging. PMID 28259365 DOI: 10.1016/J.Neurobiolaging.2017.01.022  0.467
2017 Kelly SC, He B, Perez SE, Ginsberg SD, Mufson EJ, Counts SE. Locus coeruleus cellular and molecular pathology during the progression of Alzheimer's disease. Acta Neuropathologica Communications. 5: 8. PMID 28109312 DOI: 10.1186/s40478-017-0411-2  0.456
2017 Counts SE, Mufson EJ. Regulator of Cell Cycle (RGCC) Expression During the Progression of Alzheimer's Disease. Cell Transplantation. 26: 693-702. PMID 27938491 DOI: 10.3727/096368916X694184  0.384
2017 Malek-Ahmadi M, Mufson EJ, Perez SE, Chen K. Statistical considerations for assessing cognition and neuropathology associations in preclinical Alzheimer's disease Biostatistics & Epidemiology. 1: 92-104. DOI: 10.1080/24709360.2017.1342186  0.688
2017 Malek-Ahmadi M, Lu S, Chan YY, Perez SE, Chen K, Mufson EJ. [P2-434]: INTELLECTUAL FUNCTION VERSUS YEARS OF EDUCATION AS COGNITIVE RESERVE PROXIES: INTERACTION WITH ALZHEIMER's DISEASE NEUROPATHOLOGY AND IMPACT ON EPISODIC MEMORY AND EXECUTIVE FUNCTION Alzheimer's & Dementia. 13: P802-P802. DOI: 10.1016/J.Jalz.2017.06.1090  0.65
2016 Powers BE, Kelley CM, Velazquez R, Ash JA, Strawderman MS, Alldred MJ, Ginsberg SD, Mufson EJ, Strupp BJ. Maternal choline supplementation in a mouse model of Down syndrome: effects on attention and nucleus basalis/substantia innominata neuron morphology in adult offspring. Neuroscience. PMID 27840230 DOI: 10.1016/J.Neuroscience.2016.11.001  0.771
2016 Hamlett ED, Goetzl EJ, Ledreux A, Vasilevko V, Boger HA, LaRosa A, Clark D, Carroll SL, Carmona Iragui M, Fortea J, Mufson EJ, Sabbagh M, Mohammed AH, Hartley D, Doran E, et al. Neuronal exosomes reveal Alzheimer's disease biomarkers in Down syndrome. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27755974 DOI: 10.1016/j.jalz.2016.08.012  0.418
2016 Counts SE, Ikonomovic MD, Mercado N, Vega IE, Mufson EJ. Biomarkers for the Early Detection and Progression of Alzheimer's Disease. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 27738903 DOI: 10.1007/s13311-016-0481-z  0.319
2016 Malek-Ahmadi M, Perez SE, Chen K, Mufson EJ. Neuritic and Diffuse Plaque Associations with Memory in Non-Cognitively Impaired Elderly. Journal of Alzheimer's Disease : Jad. 53: 1641-1652. PMID 27540968 DOI: 10.3233/Jad-160365  0.701
2016 Mi Z, Halfter W, Abrahamson EE, Klunk WE, Mathis CA, Mufson EJ, Ikonomovic MD. Tenascin-C is Associated with Cored Amyloid-β Plaques in Alzheimer Disease and Pathology Burdened Cognitively Normal Elderly. Journal of Neuropathology and Experimental Neurology. PMID 27444354 DOI: 10.1093/jnen/nlw062  0.336
2016 Mufson EJ, Malek-Ahmadi M, Snyder N, Ausdemore J, Chen K, Perez SE. Braak stage and trajectory of cognitive decline in noncognitively impaired elders. Neurobiology of Aging. 43: 101-10. PMID 27255819 DOI: 10.1016/J.Neurobiolaging.2016.03.003  0.703
2016 Mufson EJ, Ikonomovic MD, Counts SE, Perez SE, Malek-Ahmadi M, Scheff SW, Ginsberg SD. Molecular and Cellular Pathophysiology of Preclinical Alzheimer's Disease. Behavioural Brain Research. PMID 27185734 DOI: 10.1016/J.Bbr.2016.05.030  0.733
2016 Tiernan CT, Ginsberg SD, Guillozet-Bongaarts AL, Ward SM, He B, Kanaan NM, Mufson EJ, Binder LI, Counts SE. Protein homeostasis gene dysregulation in pretangle-bearing nucleus basalis neurons during the progression of Alzheimer's disease. Neurobiology of Aging. 42: 80-90. PMID 27143424 DOI: 10.1016/J.Neurobiolaging.2016.02.031  0.406
2016 Scheff SW, Ansari MA, Mufson EJ. Oxidative stress and hippocampal synaptic protein levels in elderly cognitively intact individuals with Alzheimer's disease pathology. Neurobiology of Aging. 42: 1-12. PMID 27143416 DOI: 10.1016/J.Neurobiolaging.2016.02.030  0.466
2016 Perez SE, Sherwood CC, Cranfield MR, Erwin JM, Mudakikwa A, Hof PR, Mufson EJ. Early Alzheimer's disease-type pathology in the frontal cortex of wild mountain gorillas (Gorilla beringei beringei). Neurobiology of Aging. 39: 195-201. PMID 26923416 DOI: 10.1016/J.Neurobiolaging.2015.12.017  0.343
2016 Counts SE, He B, Prout JG, Michalski B, Farotti L, Fahnestock M, Mufson EJ. Cerebrospinal fluid proNGF: A putative biomarker for early Alzheimer's disease. Current Alzheimer Research. PMID 26825093 DOI: 10.2174/1567205013666160129095649  0.43
2016 Mufson EJ, Malek-Ahmadi M, Perez SE, Chen K. Braak staging, plaque pathology, and APOE status in elderly persons without cognitive impairment. Neurobiology of Aging. 37: 147-53. PMID 26686670 DOI: 10.1016/J.Neurobiolaging.2015.10.012  0.717
2016 Levenson JM, Schroeter S, Carroll JC, Cullen V, Asp E, Proschitsky M, Chung CHY, Gilead S, Nadeem M, Dodiya HB, Shoaga S, Mufson EJ, Tsubery H, Krishnan R, Wright J, et al. NPT088 reduces both amyloid-β and tau pathologies in transgenic mice Alzheimer's and Dementia: Translational Research and Clinical Interventions. 2: 141-155. DOI: 10.1016/j.trci.2016.06.004  0.417
2016 Mufson EJ, Malek-Ahmadi M, Snyder N, Ausdemore J, Chen K, Perez SE. Braak stage and trajectory of cognitive decline in noncognitively impaired elders Neurobiology of Aging. 43: 101-110. DOI: 10.1016/j.neurobiolaging.2016.03.003  0.703
2016 Strupp BJ, Powers BE, Velazquez R, Ash JA, Kelley CM, Alldred MJ, Strawderman M, Caudill MA, Mufson EJ, Ginsberg SD. Maternal choline supplementation: A potential prenatal treatment for down syndrome and Alzheimer’s disease Current Alzheimer Research. 13: 97-106.  0.57
2015 Powers BE, Velazquez R, Kelley CM, Ash JA, Strawderman MS, Alldred MJ, Ginsberg SD, Mufson EJ, Strupp BJ. Attentional function and basal forebrain cholinergic neuron morphology during aging in the Ts65Dn mouse model of Down syndrome. Brain Structure & Function. PMID 26719290 DOI: 10.1007/S00429-015-1164-Y  0.731
2015 Rangasamy SB, Corbett GT, Roy A, Modi KK, Bennett DA, Mufson EJ, Ghosh S, Pahan K. Intranasal Delivery of NEMO-Binding Domain Peptide Prevents Memory Loss in a Mouse Model of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. 47: 385-402. PMID 26401561 DOI: 10.3233/Jad-150040  0.305
2015 Hamlett E, Boger HA, Ledreux A, Kelley CM, Mufson EJ, Falangola MF, Guilfoyle DN, Nixon RA, Patterson D, Duval N, Granholm AE. Cognitive Impairment, Neuroimaging, and Alzheimer Neuropathology in Mouse Models of Down Syndrome. Current Alzheimer Research. PMID 26391050 DOI: 10.2174/1567205012666150921095505  0.414
2015 Strupp BJ, Powers BE, Velazquez R, Ash JA, Kelley CM, Alldred MJ, Strawderman M, Caudill MA, Mufson EJ, Ginsberg SD. Maternal choline supplementation:A potential prenatal treatment for Down syndrome and Alzheimer's disease. Current Alzheimer Research. PMID 26391046 DOI: 10.2174/1567205012666150921100311  0.775
2015 Kelley CM, Ash JA, Powers BE, Velazquezc R, Alldred MJ, Ikonomovic MD, Ginsberg SD, Strupp BJ, Mufson EJ. Effects of Maternal Choline Supplementation on the Septohippocampal Cholinergic System in the Ts65Dn Mouse Model of Down Syndrome. Current Alzheimer Research. PMID 26391045 DOI: 10.2174/1567205012666150921100515  0.624
2015 Mufson EJ, Mahady L, Waters D, Counts SE, Perez SE, DeKosky ST, Ginsberg SD, Ikonomovic MD, Scheff SW, Binder LI. Hippocampal plasticity during the progression of Alzheimer's disease. Neuroscience. PMID 25772787 DOI: 10.1016/J.Neuroscience.2015.03.006  0.448
2015 Perez SE, He B, Nadeem M, Wuu J, Ginsberg SD, Ikonomovic MD, Mufson EJ. Hippocampal endosomal, lysosomal, and autophagic dysregulation in mild cognitive impairment: correlation with aβ and tau pathology. Journal of Neuropathology and Experimental Neurology. 74: 345-58. PMID 25756588 DOI: 10.1097/NEN.0000000000000179  0.466
2015 Scheff SW, Price DA, Ansari MA, Roberts KN, Schmitt FA, Ikonomovic MD, Mufson EJ. Synaptic change in the posterior cingulate gyrus in the progression of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 43: 1073-90. PMID 25147118 DOI: 10.3233/Jad-141518  0.428
2015 Pivtoraiko VN, Abrahamson EE, Leurgans SE, DeKosky ST, Mufson EJ, Ikonomovic MD. Cortical pyroglutamate amyloid-β levels and cognitive decline in Alzheimer's disease. Neurobiology of Aging. 36: 12-9. PMID 25048160 DOI: 10.1016/J.Neurobiolaging.2014.06.021  0.448
2015 Perez SE, He B, Nadeem M, Wuu J, Scheff SW, Abrahamson EE, Ikonomovic MD, Mufson EJ. Resilience of precuneus neurotrophic signaling pathways despite amyloid pathology in prodromal Alzheimer's disease. Biological Psychiatry. 77: 693-703. PMID 24529280 DOI: 10.1016/J.Biopsych.2013.12.016  0.37
2014 Counts SE, Perez SE, He B, Mufson EJ. Intravenous immunoglobulin reduces tau pathology and preserves neuroplastic gene expression in the 3xTg mouse model of Alzheimer's disease. Current Alzheimer Research. 11: 655-63. PMID 25156574  0.315
2014 Neuman KM, Molina-Campos E, Musial TF, Price AL, Oh KJ, Wolke ML, Buss EW, Scheff SW, Mufson EJ, Nicholson DA. Evidence for Alzheimer's disease-linked synapse loss and compensation in mouse and human hippocampal CA1 pyramidal neurons. Brain Structure & Function. PMID 25031178 DOI: 10.1007/S00429-014-0848-Z  0.307
2014 Ash JA, Velazquez R, Kelley CM, Powers BE, Ginsberg SD, Mufson EJ, Strupp BJ. Maternal choline supplementation improves spatial mapping and increases basal forebrain cholinergic neuron number and size in aged Ts65Dn mice. Neurobiology of Disease. 70: 32-42. PMID 24932939 DOI: 10.1016/J.Nbd.2014.06.001  0.741
2014 Counts SE, Alldred MJ, Che S, Ginsberg SD, Mufson EJ. Synaptic gene dysregulation within hippocampal CA1 pyramidal neurons in mild cognitive impairment. Neuropharmacology. 79: 172-9. PMID 24445080 DOI: 10.1016/J.Neuropharm.2013.10.018  0.37
2014 Kelley CM, Powers BE, Velazquez R, Ash JA, Ginsberg SD, Strupp BJ, Mufson EJ. Maternal choline supplementation differentially alters the basal forebrain cholinergic system of young-adult Ts65Dn and disomic mice. The Journal of Comparative Neurology. 522: 1390-410. PMID 24178831 DOI: 10.1002/Cne.23492  0.746
2014 Mufson EJ, Ward S, Binder L. Prefibrillar tau oligomers in mild cognitive impairment and Alzheimer's disease. Neuro-Degenerative Diseases. 13: 151-3. PMID 24029627 DOI: 10.1159/000353687  0.469
2014 Kelley CM, Powers BE, Velazquez R, Ash JA, Ginsberg SD, Strupp BJ, Mufson EJ. Sex differences in the cholinergic basal forebrain in the Ts65Dn mouse model of Down syndrome and Alzheimer's disease. Brain Pathology (Zurich, Switzerland). 24: 33-44. PMID 23802663 DOI: 10.1111/Bpa.12073  0.738
2013 Bai B, Hales CM, Chen PC, Gozal Y, Dammer EB, Fritz JJ, Wang X, Xia Q, Duong DM, Street C, Cantero G, Cheng D, Jones DR, Wu Z, Li Y, ... ... Mufson EJ, et al. U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 110: 16562-7. PMID 24023061 DOI: 10.1073/Pnas.1310249110  0.361
2013 Perez SE, Raghanti MA, Hof PR, Kramer L, Ikonomovic MD, Lacor PN, Erwin JM, Sherwood CC, Mufson EJ. Alzheimer's disease pathology in the neocortex and hippocampus of the western lowland gorilla (Gorilla gorilla gorilla). The Journal of Comparative Neurology. 521: 4318-38. PMID 23881733 DOI: 10.1002/Cne.23428  0.393
2013 Velazquez R, Ash JA, Powers BE, Kelley CM, Strawderman M, Luscher ZI, Ginsberg SD, Mufson EJ, Strupp BJ. Maternal choline supplementation improves spatial learning and adult hippocampal neurogenesis in the Ts65Dn mouse model of Down syndrome. Neurobiology of Disease. 58: 92-101. PMID 23643842 DOI: 10.1016/J.Nbd.2013.04.016  0.771
2013 Scheff SW, Price DA, Schmitt FA, Roberts KN, Ikonomovic MD, Mufson EJ. Synapse stability in the precuneus early in the progression of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 35: 599-609. PMID 23478309 DOI: 10.3233/Jad-122353  0.442
2013 Overk CR, Perez SE, Ma C, Taves MD, Soma KK, Mufson EJ. Sex steroid levels and AD-like pathology in 3xTgAD mice. Journal of Neuroendocrinology. 25: 131-44. PMID 22889357 DOI: 10.1111/j.1365-2826.2012.02374.x  0.354
2013 Counts S, Perez S, Mufson E. P2-031: IVIG reduces tau pathology and increases neuroplastic gene expression in the 3xTg mouse model of Alzheimer's disease Alzheimer's & Dementia. 9: P356-P356. DOI: 10.1016/j.jalz.2013.05.673  0.306
2013 Levenson J, Asp E, Becker M, Krishnan R, Masliah E, Mufson E, Nadeem M, Perez S, Proschitsky M, Rockenstein E, Tsubery H, Gannon K. P4-290: Novel fusion protein bivalent for a general amyloid interaction motif reduces beta-amyloid aggregates in transgenic mice Alzheimer's & Dementia. 9: P810-P810. DOI: 10.1016/J.Jalz.2013.05.1683  0.321
2012 Mufson EJ, He B, Nadeem M, Perez SE, Counts SE, Leurgans S, Fritz J, Lah J, Ginsberg SD, Wuu J, Scheff SW. Hippocampal proNGF signaling pathways and β-amyloid levels in mild cognitive impairment and Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 71: 1018-29. PMID 23095849 DOI: 10.1097/Nen.0B013E318272Caab  0.44
2012 Perez SE, Nadeem M, Sadleir KR, Matras J, Kelley CM, Counts SE, Vassar R, Mufson EJ. Dimebon alters hippocampal amyloid pathology in 3xTg-AD mice. International Journal of Physiology, Pathophysiology and Pharmacology. 4: 115-27. PMID 23071869  0.414
2012 Sager KL, Wuu J, Herskowitz JH, Mufson EJ, Levey AI, Lah JJ. Neuronal LR11 expression does not differentiate between clinically-defined Alzheimer's disease and control brains. Plos One. 7: e40527. PMID 22927900 DOI: 10.1371/Journal.Pone.0040527  0.442
2012 Counts SE, He B, Nadeem M, Wuu J, Scheff SW, Mufson EJ. Hippocampal drebrin loss in mild cognitive impairment. Neuro-Degenerative Diseases. 10: 216-9. PMID 22310934 DOI: 10.1159/000333122  0.405
2012 Perez SE, Getova DP, He B, Counts SE, Geula C, Desire L, Coutadeur S, Peillon H, Ginsberg SD, Mufson EJ. Rac1b increases with progressive tau pathology within cholinergic nucleus basalis neurons in Alzheimer's disease. The American Journal of Pathology. 180: 526-40. PMID 22142809 DOI: 10.1016/J.Ajpath.2011.10.027  0.423
2012 Mufson EJ, Binder L, Counts SE, DeKosky ST, de Toledo-Morrell L, Ginsberg SD, Ikonomovic MD, Perez SE, Scheff SW. Mild cognitive impairment: pathology and mechanisms. Acta Neuropathologica. 123: 13-30. PMID 22101321 DOI: 10.1007/S00401-011-0884-1  0.409
2012 Overk CR, Lu PY, Wang YT, Choi J, Shaw JW, Thatcher GR, Mufson EJ. Effects of aromatase inhibition versus gonadectomy on hippocampal complex amyloid pathology in triple transgenic mice. Neurobiology of Disease. 45: 479-87. PMID 21945538 DOI: 10.1016/j.nbd.2011.08.035  0.395
2012 Mufson E, Counts S, Ikonomovic M. 55 Cholinergic and amyloid activity in prodromal AD: implications for disease treatment Neurobiology of Aging. 33: S24. DOI: 10.1016/j.neurobiolaging.2012.01.073  0.347
2012 Scheff SW, Ginsberg SD, Counts SE, Mufson EJ. Synaptic integrity in mild cognitive impairment and Alzheimer's disease Research Progress in Alzheimer's Disease and Dementia (V). 23-49.  0.378
2011 Vana L, Kanaan NM, Ugwu IC, Wuu J, Mufson EJ, Binder LI. Progression of tau pathology in cholinergic Basal forebrain neurons in mild cognitive impairment and Alzheimer's disease. The American Journal of Pathology. 179: 2533-50. PMID 21945902 DOI: 10.1016/J.Ajpath.2011.07.044  0.47
2011 Ikonomovic MD, Klunk WE, Abrahamson EE, Wuu J, Mathis CA, Scheff SW, Mufson EJ, DeKosky ST. Precuneus amyloid burden is associated with reduced cholinergic activity in Alzheimer disease. Neurology. 77: 39-47. PMID 21700583 DOI: 10.1212/Wnl.0B013E3182231419  0.452
2011 Ginsberg SD, Mufson EJ, Alldred MJ, Counts SE, Wuu J, Nixon RA, Che S. Upregulation of select rab GTPases in cholinergic basal forebrain neurons in mild cognitive impairment and Alzheimer's disease. Journal of Chemical Neuroanatomy. 42: 102-10. PMID 21669283 DOI: 10.1016/J.Jchemneu.2011.05.012  0.487
2011 Elliott-Hunt CR, Holmes FE, Hartley DM, Perez S, Mufson EJ, Wynick D. Endogenous galanin protects mouse hippocampal neurons against amyloid toxicity in vitro via activation of galanin receptor-2. Journal of Alzheimer's Disease : Jad. 25: 455-62. PMID 21471641 DOI: 10.3233/Jad-2011-110011  0.311
2011 Kelley CM, Perez SE, Overk CR, Wynick D, Mufson EJ. Effect of neocortical and hippocampal amyloid deposition upon galaninergic and cholinergic neurites in AβPPswe/PS1ΔE9 mice. Journal of Alzheimer's Disease : Jad. 25: 491-504. PMID 21471639 DOI: 10.3233/Jad-2011-102097  0.356
2011 Counts SE, Che S, Ginsberg SD, Mufson EJ. Gender differences in neurotrophin and glutamate receptor expression in cholinergic nucleus basalis neurons during the progression of Alzheimer's disease. Journal of Chemical Neuroanatomy. 42: 111-7. PMID 21397006 DOI: 10.1016/j.jchemneu.2011.02.004  0.417
2011 Scheff SW, Price DA, Schmitt FA, Scheff MA, Mufson EJ. Synaptic loss in the inferior temporal gyrus in mild cognitive impairment and Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 24: 547-57. PMID 21297265 DOI: 10.3233/Jad-2011-101782  0.461
2011 Perez SE, He B, Muhammad N, Oh KJ, Fahnestock M, Ikonomovic MD, Mufson EJ. Cholinotrophic basal forebrain system alterations in 3xTg-AD transgenic mice. Neurobiology of Disease. 41: 338-52. PMID 20937383 DOI: 10.1016/J.Nbd.2010.10.002  0.405
2011 George S, Mufson EJ, Leurgans S, Shah RC, Ferrari C, deToledo-Morrell L. MRI-based volumetric measurement of the substantia innominata in amnestic MCI and mild AD. Neurobiology of Aging. 32: 1756-64. PMID 20005600 DOI: 10.1016/J.Neurobiolaging.2009.11.006  0.378
2011 Getova D, Perez S, Mufson E. P.5.d.002 Cholinergic neurons containing Rac1b in basal ganglia during neurofibrillary tangle formation in Alzheimer's disease European Neuropsychopharmacology. 21: S555-S556. DOI: 10.1016/S0924-977X(11)70905-1  0.306
2011 Mufson E, Ginsberg S. O4-02-07: Hippocampal neurotrophic signaling and endosomal-lysosomal pathway dysfunction in mild cognitive impairment Alzheimer's & Dementia. 7: S685-S685. DOI: 10.1016/J.Jalz.2011.05.1978  0.374
2010 Counts SE, Mufson EJ. PUTATIVE CSF PROTEIN BIOMARKER CANDIDATES FOR AMNESTIC MILD COGNITIVE IMPAIRMENT. Translational Neuroscience. 1: 2-8. PMID 21311725 DOI: 10.2478/v10134-010-0004-0  0.363
2010 Counts SE, Perez SE, Ginsberg SD, Mufson EJ. Neuroprotective role for galanin in Alzheimer's disease. Exs. 102: 143-62. PMID 21299067 DOI: 10.1007/978-3-0346-0228-0_11  0.478
2010 Ginsberg SD, Mufson EJ, Counts SE, Wuu J, Alldred MJ, Nixon RA, Che S. Regional selectivity of rab5 and rab7 protein upregulation in mild cognitive impairment and Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 22: 631-9. PMID 20847427 DOI: 10.3233/Jad-2010-101080  0.443
2010 Oh KJ, Perez SE, Lagalwar S, Vana L, Binder L, Mufson EJ. Staging of Alzheimer's pathology in triple transgenic mice: a light and electron microscopic analysis. International Journal of Alzheimer's Disease. 2010. PMID 20798886 DOI: 10.4061/2010/780102  0.358
2010 Ginsberg SD, Alldred MJ, Counts SE, Cataldo AM, Neve RL, Jiang Y, Wuu J, Chao MV, Mufson EJ, Nixon RA, Che S. Microarray analysis of hippocampal CA1 neurons implicates early endosomal dysfunction during Alzheimer's disease progression. Biological Psychiatry. 68: 885-93. PMID 20655510 DOI: 10.1016/J.Biopsych.2010.05.030  0.404
2010 Overk CR, Felder CC, Tu Y, Schober DA, Bales KR, Wuu J, Mufson EJ. Cortical M1 receptor concentration increases without a concomitant change in function in Alzheimer's disease. Journal of Chemical Neuroanatomy. 40: 63-70. PMID 20347961 DOI: 10.1016/J.Jchemneu.2010.03.005  0.383
2010 Mufson EJ, Leurgans S. Inability of plasma and urine F2A-isoprostane levels to differentiate mild cognitive impairment from Alzheimer's disease. Neuro-Degenerative Diseases. 7: 139-42. PMID 20197693 DOI: 10.1159/000289224  0.348
2010 Mufson EJ, Wuu J, Counts SE, Nykjaer A. Preservation of cortical sortilin protein levels in MCI and Alzheimer's disease. Neuroscience Letters. 471: 129-33. PMID 20085800 DOI: 10.1016/j.neulet.2010.01.023  0.394
2010 Perez SE, Berg BM, Moore KA, He B, Counts SE, Fritz JJ, Hu YS, Lazarov O, Lah JJ, Mufson EJ. DHA diet reduces AD pathology in young APPswe/PS1 Delta E9 transgenic mice: possible gender effects. Journal of Neuroscience Research. 88: 1026-40. PMID 19859965 DOI: 10.1002/Jnr.22266  0.311
2010 Ikonomovic M, Abrahamson E, Klunk W, Mathis C, Paljug W, Debnath M, Scheff S, Mufson E, DeKosky S. P3-194: Regional differences in amyloid load and cortical cholinergic plasticity during the progression of Alzheimer's disease Alzheimer's & Dementia. 6: S507-S507. DOI: 10.1016/J.Jalz.2010.05.1692  0.413
2009 Bruno MA, Mufson EJ, Wuu J, Cuello AC. Increased matrix metalloproteinase 9 activity in mild cognitive impairment. Journal of Neuropathology and Experimental Neurology. 68: 1309-18. PMID 19915485 DOI: 10.1097/NEN.0b013e3181c22569  0.437
2009 Counts SE, He B, Che S, Ginsberg SD, Mufson EJ. Galanin fiber hyperinnervation preserves neuroprotective gene expression in cholinergic basal forebrain neurons in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 18: 885-96. PMID 19749437 DOI: 10.3233/JAD-2009-1196  0.377
2009 Overk CR, Kelley CM, Mufson EJ. Brainstem Alzheimer's-like pathology in the triple transgenic mouse model of Alzheimer's disease. Neurobiology of Disease. 35: 415-25. PMID 19524671 DOI: 10.1016/J.Nbd.2009.06.004  0.354
2009 Ikonomovic MD, Wecker L, Abrahamson EE, Wuu J, Counts SE, Ginsberg SD, Mufson EJ, Dekosky ST. Cortical alpha7 nicotinic acetylcholine receptor and beta-amyloid levels in early Alzheimer disease. Archives of Neurology. 66: 646-51. PMID 19433665 DOI: 10.1001/Archneurol.2009.46  0.319
2008 Mufson EJ, Counts SE, Perez SE, Ginsberg SD. Cholinergic system during the progression of Alzheimer's disease: therapeutic implications. Expert Review of Neurotherapeutics. 8: 1703-18. PMID 18986241 DOI: 10.1586/14737175.8.11.1703  0.435
2008 Counts SE, Perez SE, Mufson EJ. Galanin in Alzheimer's disease: neuroinhibitory or neuroprotective? Cellular and Molecular Life Sciences : Cmls. 65: 1842-53. PMID 18500641 DOI: 10.1007/s00018-008-8159-2  0.476
2008 Wang DS, Uchikado H, Bennett DA, Schneider JA, Mufson EJ, Wu J, Dickson DW. Cognitive performance correlates with cortical isopeptide immunoreactivity as well as Alzheimer type pathology. Journal of Alzheimer's Disease : Jad. 13: 53-66. PMID 18334757 DOI: 10.3233/Jad-2008-13106  0.417
2008 Counts SE, He B, Che S, Ginsberg SD, Mufson EJ. Galanin hyperinnervation upregulates choline acetyltransferase expression in cholinergic basal forebrain neurons in Alzheimer's disease. Neuro-Degenerative Diseases. 5: 228-31. PMID 18322398 DOI: 10.1159/000113710  0.389
2008 Overk CR, Oh K, Perez SE, Mufson EJ. P1-051: Brainstem Alzheimer's disease-like neuropathology in triple transgenic mice Alzheimer's & Dementia. 4: T220-T221. DOI: 10.1016/j.jalz.2008.05.637  0.324
2008 Oh K, Overk CR, Perez SE, Mufson EJ. P1-025: Intraneuronal Tau immunoreactivity is fixation dependent in young 3xTg-AD mice Alzheimer's & Dementia. 4: T212-T213. DOI: 10.1016/j.jalz.2008.05.610  0.324
2008 Scheff SW, Price DA, Schmitt FA, Mufson EJ. P4-158: Preservation of synaptic numbers in the precuneus associated with mild cognitive impairment and mild-to-moderate Alzheimer's disease Alzheimer's & Dementia. 4: T716-T717. DOI: 10.1016/J.Jalz.2008.05.2225  0.389
2007 Counts SE, He B, Che S, Ikonomovic MD, DeKosky ST, Ginsberg SD, Mufson EJ. Alpha7 nicotinic receptor up-regulation in cholinergic basal forebrain neurons in Alzheimer disease. Archives of Neurology. 64: 1771-6. PMID 18071042 DOI: 10.1001/Archneur.64.12.1771  0.399
2007 Mufson EJ, Counts SE, Fahnestock M, Ginsberg SD. Cholinotrophic molecular substrates of mild cognitive impairment in the elderly. Current Alzheimer Research. 4: 340-50. PMID 17908035 DOI: 10.2174/156720507781788855  0.462
2007 Ikonomovic MD, Abrahamson EE, Isanski BA, Wuu J, Mufson EJ, DeKosky ST. Superior frontal cortex cholinergic axon density in mild cognitive impairment and early Alzheimer disease. Archives of Neurology. 64: 1312-7. PMID 17846271 DOI: 10.1001/Archneur.64.9.1312  0.356
2007 Sager KL, Wuu J, Leurgans SE, Rees HD, Gearing M, Mufson EJ, Levey AI, Lah JJ. Neuronal LR11/sorLA expression is reduced in mild cognitive impairment. Annals of Neurology. 62: 640-7. PMID 17721864 DOI: 10.1002/Ana.21190  0.484
2007 Scheff SW, Price DA, Schmitt FA, DeKosky ST, Mufson EJ. Synaptic alterations in CA1 in mild Alzheimer disease and mild cognitive impairment. Neurology. 68: 1501-8. PMID 17470753 DOI: 10.1212/01.Wnl.0000260698.46517.8F  0.356
2007 Albrecht S, Bourdeau M, Bennett D, Mufson EJ, Bhattacharjee M, LeBlanc AC. Activation of caspase-6 in aging and mild cognitive impairment. The American Journal of Pathology. 170: 1200-9. PMID 17392160 DOI: 10.2353/Ajpath.2007.060974  0.415
2007 Forman MS, Mufson EJ, Leurgans S, Pratico D, Joyce S, Leight S, Lee VM, Trojanowski JQ. Cortical biochemistry in MCI and Alzheimer disease: lack of correlation with clinical diagnosis. Neurology. 68: 757-63. PMID 17339583 DOI: 10.1212/01.Wnl.0000256373.39415.B1  0.427
2006 Ginsberg SD, Che S, Counts SE, Mufson EJ. Single cell gene expression profiling in Alzheimer's disease. Neurorx : the Journal of the American Society For Experimental Neurotherapeutics. 3: 302-18. PMID 16815214 DOI: 10.1016/j.nurx.2006.05.007  0.322
2006 Counts SE, Nadeem M, Lad SP, Wuu J, Mufson EJ. Differential expression of synaptic proteins in the frontal and temporal cortex of elderly subjects with mild cognitive impairment. Journal of Neuropathology and Experimental Neurology. 65: 592-601. PMID 16783169 DOI: 10.1097/00005072-200606000-00007  0.371
2006 Dubelaar EJ, Mufson EJ, ter Meulen WG, Van Heerikhuize JJ, Verwer RW, Swaab DF. Increased metabolic activity in nucleus basalis of Meynert neurons in elderly individuals with mild cognitive impairment as indicated by the size of the Golgi apparatus. Journal of Neuropathology and Experimental Neurology. 65: 257-66. PMID 16651887 DOI: 10.1097/01.jnen.0000205143.16339.cd  0.339
2006 Ginsberg SD, Che S, Wuu J, Counts SE, Mufson EJ. Down regulation of trk but not p75NTR gene expression in single cholinergic basal forebrain neurons mark the progression of Alzheimer's disease. Journal of Neurochemistry. 97: 475-87. PMID 16539663 DOI: 10.1111/j.1471-4159.2006.03764.x  0.454
2006 Ginsberg SD, Che S, Counts SE, Mufson EJ. Shift in the ratio of three-repeat tau and four-repeat tau mRNAs in individual cholinergic basal forebrain neurons in mild cognitive impairment and Alzheimer's disease. Journal of Neurochemistry. 96: 1401-8. PMID 16478530 DOI: 10.1111/j.1471-4159.2005.03641.x  0.455
2006 Counts SE, Chen EY, Che S, Ikonomovic MD, Wuu J, Ginsberg SD, Dekosky ST, Mufson EJ. Galanin fiber hypertrophy within the cholinergic nucleus basalis during the progression of Alzheimer's disease. Dementia and Geriatric Cognitive Disorders. 21: 205-14. PMID 16410678 DOI: 10.1159/000090906  0.385
2006 Scheff SW, Price DA, Schmitt FA, Mufson EJ. Hippocampal synaptic loss in early Alzheimer's disease and mild cognitive impairment. Neurobiology of Aging. 27: 1372-84. PMID 16289476 DOI: 10.1016/J.Neurobiolaging.2005.09.012  0.327
2006 Malek-Ahmadi M, Chen K, Perez SE, Mufson EJ. O2-03-04: CEREBRAL AMYLOID ANGIOPATHY CORRELATES WITH COGNITIVE DECLINE IN PRECLINICAL AD Alzheimer's & Dementia. 14: P617-P617. DOI: 10.1016/J.Jalz.2018.06.2654  0.679
2006 Forman MS, Leurgans S, Pratico D, Joyce S, Leight S, Mufson EJ, Lee VM, Trojanowski JQ. P2-207: Cortical biochemical markers of mild cognitive impairment Alzheimer's & Dementia. 2: S296-S296. DOI: 10.1016/J.Jalz.2006.05.1046  0.306
2005 Perez SE, Lazarov O, Koprich JB, Chen EY, Rodriguez-Menendez V, Lipton JW, Sisodia SS, Mufson EJ. Nigrostriatal dysfunction in familial Alzheimer's disease-linked APPswe/PS1DeltaE9 transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 10220-9. PMID 16267229 DOI: 10.1523/Jneurosci.2773-05.2005  0.34
2005 Peng S, Wuu J, Mufson EJ, Fahnestock M. Precursor form of brain-derived neurotrophic factor and mature brain-derived neurotrophic factor are decreased in the pre-clinical stages of Alzheimer's disease. Journal of Neurochemistry. 93: 1412-21. PMID 15935057 DOI: 10.1111/J.1471-4159.2005.03135.X  0.44
2005 Mufson EJ, Counts SE, Perez SE, Binder L. Galanin plasticity in the cholinergic basal forebrain in Alzheimer's disease and transgenic mice. Neuropeptides. 39: 233-7. PMID 15893372 DOI: 10.1016/J.Npep.2004.12.005  0.443
2005 Tuszynski MH, Thal L, Pay M, Salmon DP, U HS, Bakay R, Patel P, Blesch A, Vahlsing HL, Ho G, Tong G, Potkin SG, Fallon J, Hansen L, Mufson EJ, et al. A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease. Nature Medicine. 11: 551-5. PMID 15852017 DOI: 10.1038/Nm1239  0.36
2005 Counts SE, Mufson EJ. The role of nerve growth factor receptors in cholinergic basal forebrain degeneration in prodromal Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 64: 263-72. PMID 15835262  0.36
2005 Ikonomovic MD, Mufson EJ, Wuu J, Bennett DA, DeKosky ST. Reduction of choline acetyltransferase activity in primary visual cortex in mild to moderate Alzheimer's disease. Archives of Neurology. 62: 425-30. PMID 15767507 DOI: 10.1001/Archneur.62.3.425  0.413
2005 Georganopoulou DG, Chang L, Nam JM, Thaxton CS, Mufson EJ, Klein WL, Mirkin CA. Nanoparticle-based detection in cerebral spinal fluid of a soluble pathogenic biomarker for Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 102: 2273-6. PMID 15695586 DOI: 10.1073/Pnas.0409336102  0.315
2004 Counts SE, Nadeem M, Wuu J, Ginsberg SD, Saragovi HU, Mufson EJ. Reduction of cortical TrkA but not p75(NTR) protein in early-stage Alzheimer's disease. Annals of Neurology. 56: 520-31. PMID 15455399 DOI: 10.1002/Ana.20233  0.42
2004 Peng S, Wuu J, Mufson EJ, Fahnestock M. Increased proNGF levels in subjects with mild cognitive impairment and mild Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 63: 641-9. PMID 15217092 DOI: 10.1093/Jnen/63.6.641  0.473
2004 Wang DS, Bennett DA, Mufson E, Cochran E, Dickson DW. Decreases in soluble alpha-synuclein in frontal cortex correlate with cognitive decline in the elderly. Neuroscience Letters. 359: 104-8. PMID 15050722 DOI: 10.1016/J.Neulet.2004.01.044  0.456
2004 Wang DS, Bennett DA, Mufson EJ, Mattila P, Cochran E, Dickson DW. Contribution of changes in ubiquitin and myelin basic protein to age-related cognitive decline. Neuroscience Research. 48: 93-100. PMID 14687885 DOI: 10.1016/J.Neures.2003.10.002  0.387
2004 Wang D, Fujino Y, Bennett D, Mufson EJ, Cochran E, Dickson DW. P3-278 Increased tissue transglutaminase correlates with Alzheimer pathology and cognitive status Neurobiology of Aging. 25: S433-S434. DOI: 10.1016/S0197-4580(04)81428-3  0.355
2004 Scheff SW, Price DA, Schmitt FA, Cochran EJ, Bennett DA, Mufson EJ. P3-170 Stereological assessment of hippocampal synapses in people with Alzheimer's disease and mild cognitive impairment Neurobiology of Aging. 25: S404. DOI: 10.1016/S0197-4580(04)81322-8  0.382
2004 Mufson EJ. P1-252 Early cholinotrophic basal forebrain neurodegenerative events in mild cognitive impairment: back to the future Neurobiology of Aging. 25: S167-S168. DOI: 10.1016/S0197-4580(04)80565-7  0.315
2003 Counts SE, Perez SE, Ginsberg SD, De Lacalle S, Mufson EJ. Galanin in Alzheimer disease. Molecular Interventions. 3: 137-56. PMID 14993421 DOI: 10.1124/mi.3.3.137  0.425
2003 Mufson EJ, Ginsberg SD, Ikonomovic MD, DeKosky ST. Human cholinergic basal forebrain: chemoanatomy and neurologic dysfunction. Journal of Chemical Neuroanatomy. 26: 233-42. PMID 14729126 DOI: 10.1016/S0891-0618(03)00068-1  0.363
2003 Lad SP, Neet KE, Mufson EJ. Nerve growth factor: structure, function and therapeutic implications for Alzheimer's disease. Current Drug Targets. Cns and Neurological Disorders. 2: 315-34. PMID 14529363 DOI: 10.2174/1568007033482724  0.407
2003 Mufson EJ, Ikonomovic MD, Styren SD, Counts SE, Wuu J, Leurgans S, Bennett DA, Cochran EJ, DeKosky ST. Preservation of brain nerve growth factor in mild cognitive impairment and Alzheimer disease. Archives of Neurology. 60: 1143-8. PMID 12925373 DOI: 10.1001/Archneur.60.8.1143  0.431
2003 Yang Y, Mufson EJ, Herrup K. Neuronal cell death is preceded by cell cycle events at all stages of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 2557-63. PMID 12684440 DOI: 10.1523/Jneurosci.23-07-02557.2003  0.415
2003 Ikonomovic MD, Mufson EJ, Wuu J, Cochran EJ, Bennett DA, DeKosky ST. Cholinergic plasticity in hippocampus of individuals with mild cognitive impairment: correlation with Alzheimer's neuropathology. Journal of Alzheimer's Disease : Jad. 5: 39-48. PMID 12590165 DOI: 10.3233/Jad-2003-5106  0.461
2002 Mufson EJ, Counts SE, Ginsberg SD. Gene expression profiles of cholinergic nucleus basalis neurons in Alzheimer's disease. Neurochemical Research. 27: 1035-48. PMID 12462403 DOI: 10.1023/A:1020952704398  0.337
2002 Granholm AC, Ford KA, Hyde LA, Bimonte HA, Hunter CL, Nelson M, Albeck D, Sanders LA, Mufson EJ, Crnic LS. Estrogen restores cognition and cholinergic phenotype in an animal model of Down syndrome. Physiology & Behavior. 77: 371-85. PMID 12419414 DOI: 10.1016/S0031-9384(02)00884-3  0.424
2002 Pérez S, Basile M, Mash DC, Mufson EJ. Galanin receptor over-expression within the amygdala in early Alzheimer's disease: an in vitro autoradiographic analysis. Journal of Chemical Neuroanatomy. 24: 109-16. PMID 12191727 DOI: 10.1016/S0891-0618(02)00034-0  0.367
2002 Mitchell TW, Mufson EJ, Schneider JA, Cochran EJ, Nissanov J, Han LY, Bienias JL, Lee VM, Trojanowski JQ, Bennett DA, Arnold SE. Parahippocampal tau pathology in healthy aging, mild cognitive impairment, and early Alzheimer's disease. Annals of Neurology. 51: 182-9. PMID 11835374 DOI: 10.1002/Ana.10086  0.456
2002 DeKosky ST, Ikonomovic MD, Styren SD, Beckett L, Wisniewski S, Bennett DA, Cochran EJ, Kordower JH, Mufson EJ. Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment. Annals of Neurology. 51: 145-55. PMID 11835370 DOI: 10.1002/Ana.10069  0.447
2002 Mufson EJ, Ma SY, Dills J, Cochran EJ, Leurgans S, Wuu J, Bennett DA, Jaffar S, Gilmor ML, Levey AI, Kordower JH. Loss of basal forebrain P75(NTR) immunoreactivity in subjects with mild cognitive impairment and Alzheimer's disease. The Journal of Comparative Neurology. 443: 136-53. PMID 11793352 DOI: 10.1002/Cne.10122  0.47
2002 Schneider JA, Bienias JL, Gilley DW, Kvarnberg DE, Mufson EJ, Bennett DA. Improved detection of substantia nigra pathology in Alzheimer's disease. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 50: 99-106. PMID 11748299 DOI: 10.1177/002215540205000111  0.303
2001 Counts SE, Perez SE, Kahl U, Bartfai T, Bowser RP, Deecher DC, Mash DC, Crawley JN, Mufson EJ. Galanin: neurobiologic mechanisms and therapeutic potential for Alzheimer's disease. Cns Drug Reviews. 7: 445-70. PMID 11830760 DOI: 10.1111/J.1527-3458.2001.Tb00210.X  0.44
2001 Gómez-Ramos P, Mufson EJ, Morán MA. Apolipoprotein E immunoreactivity in neurons and neurofibrillary degeneration of aged non-demented and Alzheimer's disease patients. Microscopy Research and Technique. 55: 48-58. PMID 11596149 DOI: 10.1002/jemt.1155  0.338
2001 Chu Y, Cochran EJ, Bennett DA, Mufson EJ, Kordower JH. Down-regulation of trkA mRNA within nucleus basalis neurons in individuals with mild cognitive impairment and Alzheimer's disease. The Journal of Comparative Neurology. 437: 296-307. PMID 11494257 DOI: 10.1002/Cne.1284  0.459
2001 Jaffar S, Counts SE, Ma SY, Dadko E, Gordon MN, Morgan D, Mufson EJ. Neuropathology of mice carrying mutant APP(swe) and/or PS1(M146L) transgenes: alterations in the p75(NTR) cholinergic basal forebrain septohippocampal pathway. Experimental Neurology. 170: 227-43. PMID 11476589 DOI: 10.1006/Exnr.2001.7710  0.315
2001 Ghoshal N, García-Sierra F, Fu Y, Beckett LA, Mufson EJ, Kuret J, Berry RW, Binder LI. Tau-66: evidence for a novel tau conformation in Alzheimer's disease. Journal of Neurochemistry. 77: 1372-85. PMID 11389188 DOI: 10.1046/J.1471-4159.2001.00346.X  0.304
2001 Steiner RA, Hohmann JG, Holmes A, Wrenn CC, Cadd G, Juréus A, Clifton DK, Luo M, Gutshall M, Ma SY, Mufson EJ, Crawley JN. Galanin transgenic mice display cognitive and neurochemical deficits characteristic of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 98: 4184-9. PMID 11259657 DOI: 10.1073/Pnas.061445598  0.462
2001 Kordower JH, Chu Y, Stebbins GT, DeKosky ST, Cochran EJ, Bennett D, Mufson EJ. Loss and atrophy of layer II entorhinal cortex neurons in elderly people with mild cognitive impairment. Annals of Neurology. 49: 202-13. PMID 11220740 DOI: 10.1002/1531-8249(20010201)49:2<202::Aid-Ana40>3.0.Co;2-3  0.38
2000 Mitchell TW, Nissanov J, Han LY, Mufson EJ, Schneider JA, Cochran EJ, Bennett DA, Lee VM, Trojanowski JQ, Arnold SE. Novel method to quantify neuropil threads in brains from elders with or without cognitive impairment. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 48: 1627-38. PMID 11101631 DOI: 10.1177/002215540004801206  0.423
2000 Mufson EJ, Ma SY, Cochran EJ, Bennett DA, Beckett LA, Jaffar S, Saragovi HU, Kordower JH. Loss of nucleus basalis neurons containing trkA immunoreactivity in individuals with mild cognitive impairment and early Alzheimer's disease. The Journal of Comparative Neurology. 427: 19-30. PMID 11042589 DOI: 10.1002/1096-9861(20001106)427:1<19::Aid-Cne2>3.0.Co;2-A  0.483
2000 Mufson EJ, Deecher DC, Basile M, Izenwasse S, Mash DC. Galanin receptor plasticity within the nucleus basalis in early and late Alzheimer's disease: an in vitro autoradiographic analysis. Neuropharmacology. 39: 1404-12. PMID 10818256 DOI: 10.1016/S0028-3908(00)00011-3  0.355
2000 Mufson EJ, Ma SY, Gilmor ML, Bennett DA, Beckett LA, Cochran EJ, Levey AI, Kordower JH. Cholinergic and neurotrophic markers within the nucleus basalis in elderly individuals with mild cognitive impairment and early Alzheimer's disease Neurobiology of Aging. 21: 270-271. DOI: 10.1016/S0197-4580(00)83170-X  0.434
2000 Schneider JA, Wilson RS, Li J, Mufson EJ, Bennett DA. Apolipoprotein E, amyloid beta 40 and 42, and cognitive function in aging and Alzheimer's disease Neurobiology of Aging. 21: 120. DOI: 10.1016/S0197-4580(00)82341-6  0.371
1999 Gilmor ML, Erickson JD, Varoqui H, Hersh LB, Bennett DA, Cochran EJ, Mufson EJ, Levey AI. Preservation of nucleus basalis neurons containing choline acetyltransferase and the vesicular acetylcholine transporter in the elderly with mild cognitive impairment and early Alzheimer's disease. The Journal of Comparative Neurology. 411: 693-704. PMID 10421878 DOI: 10.1002/(Sici)1096-9861(19990906)411:4<693::Aid-Cne13>3.0.Co;2-D  0.462
1999 Mufson EJ, Chen EY, Cochran EJ, Beckett LA, Bennett DA, Kordower JH. Entorhinal cortex beta-amyloid load in individuals with mild cognitive impairment. Experimental Neurology. 158: 469-90. PMID 10415154 DOI: 10.1006/Exnr.1999.7086  0.335
1998 Mufson EJ, Kahl U, Bowser R, Mash DC, Kordower JH, Deecher DC. Galanin expression within the basal forebrain in Alzheimer's disease. Comments on therapeutic potential. Annals of the New York Academy of Sciences. 863: 291-304. PMID 9928179 DOI: 10.1111/J.1749-6632.1998.Tb10703.X  0.356
1997 Mufson EJ, Lavine N, Jaffar S, Kordower JH, Quirion R, Saragovi HU. Reduction in p140-TrkA receptor protein within the nucleus basalis and cortex in Alzheimer's disease. Experimental Neurology. 146: 91-103. PMID 9225742 DOI: 10.1006/Exnr.1997.6504  0.363
1997 Bowser R, Kordower JH, Mufson EJ. A confocal microscopic analysis of galaninergic hyperinnervation of cholinergic basal forebrain neurons in Alzheimer's disease. Brain Pathology (Zurich, Switzerland). 7: 723-30. PMID 9161723 DOI: 10.1111/J.1750-3639.1997.Tb01058.X  0.324
1996 Mufson EJ, Li JM, Sobreviela T, Kordower JH. Decreased trkA gene expression within basal forebrain neurons in Alzheimer's disease. Neuroreport. 8: 25-9. PMID 9051746 DOI: 10.1097/00001756-199612200-00006  0.364
1996 Mochizuki A, Peterson JW, Mufson EJ, Trapp BD. Amyloid load and neural elements in Alzheimer's disease and nondemented individuals with high amyloid plaque density. Experimental Neurology. 142: 89-102. PMID 8912901 DOI: 10.1006/Exnr.1996.0181  0.366
1995 Scott SA, Mufson EJ, Weingartner JA, Skau KA, Crutcher KA. Nerve growth factor in Alzheimer's disease: increased levels throughout the brain coupled with declines in nucleus basalis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 6213-21. PMID 7666203 DOI: 10.1523/Jneurosci.15-09-06213.1995  0.357
1995 Mufson EJ, Conner JM, Kordower JH. Nerve growth factor in Alzheimer's disease: defective retrograde transport to nucleus basalis. Neuroreport. 6: 1063-6. PMID 7632896 DOI: 10.1097/00001756-199505090-00028  0.336
1995 Benzing WC, Mufson EJ. Apolipoprotein E immunoreactivity within neurofibrillary tangles: relationship to Tau and PHF in Alzheimer's disease. Experimental Neurology. 132: 162-71. PMID 7540552 DOI: 10.1016/0014-4886(95)90021-7  0.37
1994 Cochran EJ, Fox JH, Mufson EJ. Severe panencephalic Pick's disease with Alzheimer's disease-like neuropil threads and synaptophysin immunoreactivity. Acta Neuropathologica. 88: 479-84. PMID 7847079 DOI: 10.1007/Bf00389503  0.37
1993 Benzing WC, Mufson EJ, Armstrong DM. Immunocytochemical distribution of peptidergic and cholinergic fibers in the human amygdala: their depletion in Alzheimer's disease and morphologic alteration in non-demented elderly with numerous senile plaques. Brain Research. 625: 125-38. PMID 8242391 DOI: 10.1016/0006-8993(93)90145-D  0.315
1993 Benzing WC, Mufson EJ, Armstrong DM. Alzheimer's disease-like dystrophic neurites characteristically associated with senile plaques are not found within other neurodegenerative diseases unless amyloid beta-protein deposition is present. Brain Research. 606: 10-8. PMID 8096426 DOI: 10.1016/0006-8993(93)91563-8  0.359
1993 Wainer BH, Steininger TL, Roback JD, Burke-Watson MA, Mufson EJ, Kordower J. Ascending cholinergic pathways: functional organization and implications for disease models. Progress in Brain Research. 98: 9-30. PMID 7902596 DOI: 10.1016/S0079-6123(08)62378-X  0.311
1993 Benzing WC, Brady DR, Mufson EJ, Armstrong DM. Evidence that transmitter-containing dystrophic neurites precede those containing paired helical filaments within senile plaques in the entorhinal cortex of nondemented elderly and Alzheimer's disease patients. Brain Research. 619: 55-68. PMID 7690677 DOI: 10.1016/0006-8993(93)91595-J  0.323
1992 Morán MA, Cebrián JL, Gómez-Ramos P, Cabello A, Madero S, Mufson EJ. [Diagnosis of Alzheimer's disease. Evaluation of senile plaques of the diffuse type]. Medicina Clã­Nica. 98: 19-23. PMID 1545606  0.365
1992 Mufson EJ, Kordower JH. Cortical neurons express nerve growth factor receptors in advanced age and Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 89: 569-73. PMID 1309947 DOI: 10.1073/Pnas.89.2.569  0.308
1990 Benzing WC, Mufson EJ, Jennes L, Armstrong DM. Reduction of neurotensin immunoreactivity in the amygdala in Alzheimer's disease. Brain Research. 537: 298-302. PMID 1707731 DOI: 10.1016/0006-8993(90)90372-I  0.361
1990 Brady DR, Mufson EJ. Amygdaloid pathology in alzheimer’s disease: Qualitative and quantitative analysis Dementia and Geriatric Cognitive Disorders. 1: 5-17. DOI: 10.1159/000107115  0.341
1989 Kordower JH, Mufson EJ. NGF and Alzheimer's disease: unfulfilled promise and untapped potential. Neurobiology of Aging. 10: 543-4; discussion 55. PMID 2812223 DOI: 10.1016/0197-4580(89)90123-1  0.312
1989 Benowitz LI, Rodriguez W, Paskevich P, Mufson EJ, Schenk D, Neve RL. The amyloid precursor protein is concentrated in neuronal lysosomes in normal and Alzheimer disease subjects. Experimental Neurology. 106: 237-50. PMID 2591522 DOI: 10.1016/0014-4886(89)90156-8  0.327
1989 Higgins GA, Mufson EJ. NGF receptor gene expression is decreased in the nucleus basalis in Alzheimer's disease. Experimental Neurology. 106: 222-36. PMID 2556292  0.304
1988 Mufson EJ, Mash DC, Hersh LB. Neurofibrillary tangles in cholinergic pedunculopontine neurons in Alzheimer's disease. Annals of Neurology. 24: 623-9. PMID 3202615 DOI: 10.1002/Ana.410240506  0.351
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