Ling Qi, Ph.D. - Publications

Affiliations: 
2002 University of Maryland, Baltimore County 
 2016- University of Michigan Medical School, Ann Arbor, MI, United States 
Area:
Immunology, Protein degradation, Endoplasmic reticulum, beta-cells inflamation
Website:
https://sites.google.com/a/umich.edu/ling-qi-lab/

53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Bhattacharya A, Qi L. ER-associated degradation in health and disease - from substrate to organism. Journal of Cell Science. 132. PMID 31792042 DOI: 10.1242/jcs.232850  0.52
2019 Shen H, Ji Y, Xiong Y, Kim H, Zhong X, Jin MG, Shah YM, Omary MB, Liu Y, Qi L, Rui L. Medullary thymic epithelial NF-kB-inducing kinase (NIK)/IKKα pathway shapes autoimmunity and liver and lung homeostasis in mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 31481626 DOI: 10.1073/pnas.1901056116  0.52
2019 Xiong X, Kuang H, Ansari S, Liu T, Gong J, Wang S, Zhao XY, Ji Y, Li C, Guo L, Zhou L, Chen Z, Leon-Mimila P, Chung MT, Kurabayashi K, ... ... Qi L, et al. Landscape of Intercellular Crosstalk in Healthy and NASH Liver Revealed by Single-Cell Secretome Gene Analysis. Molecular Cell. 75: 644-660.e5. PMID 31398325 DOI: 10.1016/j.molcel.2019.07.028  0.44
2019 Ji Y, Sun S, Shrestha N, Darragh LB, Shirakawa J, Xing Y, He Y, Carboneau BA, Kim H, An D, Ma M, Oberholzer J, Soleimanpour SA, Gannon M, Liu C, ... ... Qi L, et al. Toll-like receptors TLR2 and TLR4 block the replication of pancreatic β cells in diet-induced obesity. Nature Immunology. PMID 31110312 DOI: 10.1038/s41590-019-0396-z  0.52
2018 Bhattacharya A, Sun S, Wang H, Liu M, Long Q, Yin L, Kersten S, Zhang K, Qi L. Hepatic Sel1L-Hrd1 ER-associated degradation (ERAD) manages FGF21 levels and systemic metabolism via CREBH. The Embo Journal. PMID 30389665 DOI: 10.15252/embj.201899277  0.52
2017 An D, Chiu A, Flanders JA, Song W, Shou D, Lu YC, Grunnet LG, Winkel L, Ingvorsen C, Christophersen NS, Fels JJ, Sand FW, Ji Y, Qi L, Pardo Y, et al. Designing a retrievable and scalable cell encapsulation device for potential treatment of type 1 diabetes. Proceedings of the National Academy of Sciences of the United States of America. PMID 29279393 DOI: 10.1073/pnas.1708806115  0.44
2017 Oteng AB, Bhattacharya A, Brodesser S, Qi L, Tan NS, Kersten S. Feeding Angptl4-/- mice trans fat promotes foam cell formation in mesenteric lymph nodes without leading to ascites. Journal of Lipid Research. PMID 28412693 DOI: 10.1194/jlr.M074278  0.52
2017 Zhu S, Liu H, Sha H, Qi L, Gao DS, Zhang W. PERK and XBP1 differentially regulate CXCL10 and CCL2 production. Experimental Eye Research. PMID 28065589 DOI: 10.1016/j.exer.2017.01.002  0.44
2016 Ji Y, Kim H, Yang L, Sha H, Roman CA, Long Q, Qi L. The Sel1L-Hrd1 Endoplasmic Reticulum-Associated Degradation Complex Manages a Key Checkpoint in B Cell Development. Cell Reports. PMID 27568564 DOI: 10.1016/j.celrep.2016.08.003  0.52
2016 Tang J, Li J, Zhu X, Yu Y, Chen D, Yuan L, Gu Z, Zhang X, Qi L, Gong Z, Jiang P, Yu J, Meng H, An G, Zheng H, et al. Novel CD7-specific nanobody-based immunotoxins potently enhanced apoptosis of CD7-positive malignant cells. Oncotarget. PMID 27083001 DOI: 10.18632/oncotarget.8710  0.44
2016 Han Rs, Qi Lq, Hou X, Liu Lh, Liu Hy, Xian XN, Guo GX, Sun Hy. Magnetic contribution of Bi0.85La0.15FeO3 in (1−x)Bi0.85La0.15FeO3–(x)CoFe2O4 nanocomposite powders Journal of Magnetism and Magnetic Materials. 420: 117-121. DOI: 10.1016/j.jmmm.2016.07.032  0.44
2016 Zhu F, Peng Y, Qi L, Bi G, He Y, Jie C, Yang R, Yan P, Yang L, Chen J, Xiao W, Zuo X, Chen X, Zu X, Guan X, et al. Nested ARMS-qPCR is a fast and cost-saving method for single nucleotide polymorphism genotyping in clinical service International Journal of Clinical and Experimental Medicine. 9: 16292-16300.  0.44
2015 Sun S, Lourie R, Cohen SB, Ji Y, Goodrich JK, Poole AC, Ley RE, Denkers EY, McGuckin MA, Long Q, Duhamel GE, Simpson KW, Qi L. Epithelial Sel1L is required for the maintenance of intestinal homeostasis. Molecular Biology of the Cell. PMID 26631554 DOI: 10.1091/mbc.E15-10-0724  0.44
2015 Sun S, Shi G, Sha H, Ji Y, Han X, Shu X, Ma H, Inoue T, Gao B, Kim H, Bu P, Guber RD, Shen X, Lee AH, Iwawaki T, ... ... Qi L, et al. IRE1α is an endogenous substrate of endoplasmic-reticulum-associated degradation. Nature Cell Biology. PMID 26551274 DOI: 10.1038/ncb3266  0.52
2015 Xia S, Li XP, Cheng L, Han MT, Zhang MM, Shao QX, Xu HX, Qi L. Fish Oil-Rich Diet Promotes Hematopoiesis and Alters Hematopoietic Niche. Endocrinology. 156: 2821-30. PMID 26061726 DOI: 10.1210/en.2015-1258  0.44
2015 Kim H, Bhattacharya A, Qi L. Endoplasmic reticulum quality control in cancer: Friend or foe. Seminars in Cancer Biology. PMID 25794824 DOI: 10.1016/j.semcancer.2015.02.003  0.52
2015 An D, Ji Y, Chiu A, Lu YC, Song W, Zhai L, Qi L, Luo D, Ma M. Developing robust, hydrogel-based, nanofiber-enabled encapsulation devices (NEEDs) for cell therapies. Biomaterials. 37: 40-8. PMID 25453936 DOI: 10.1016/j.biomaterials.2014.10.032  0.44
2014 Sha H, Sun S, Francisco AB, Ehrhardt N, Xue Z, Liu L, Lawrence P, Mattijssen F, Guber RD, Panhwar MS, Brenna JT, Shi H, Xue B, Kersten S, Bensadoun A, ... ... Qi L, et al. The ER-associated degradation adaptor protein Sel1L regulates LPL secretion and lipid metabolism. Cell Metabolism. 20: 458-70. PMID 25066055 DOI: 10.1016/j.cmet.2014.06.015  0.44
2014 Ji Y, Sun S, Goodrich JK, Kim H, Poole AC, Duhamel GE, Ley RE, Qi L. Diet-induced alterations in gut microflora contribute to lethal pulmonary damage in TLR2/TLR4-deficient mice. Cell Reports. 8: 137-49. PMID 24953658 DOI: 10.1016/j.celrep.2014.05.040  0.44
2014 An D, Lessard SJ, Toyoda T, Lee MY, Koh HJ, Qi L, Hirshman MF, Goodyear LJ. Overexpression of TRB3 in muscle alters muscle fiber type and improves exercise capacity in mice. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 306: R925-33. PMID 24740654 DOI: 10.1152/ajpregu.00027.2014  0.44
2014 Xia S, Li X, Cheng L, Han M, Zhang M, Liu X, Xu H, Zhang M, Shao Q, Qi L. Chronic intake of high fish oil diet induces myeloid-derived suppressor cells to promote tumor growth. Cancer Immunology, Immunotherapy : Cii. 63: 663-73. PMID 24691944 DOI: 10.1007/s00262-014-1546-7  0.44
2014 Qi L. Tipping the balance in metabolic regulation: regulating regulatory T cells by costimulation. Diabetes. 63: 1179-81. PMID 24651799 DOI: 10.2337/db13-1915  0.44
2014 Sun S, Shi G, Han X, Francisco AB, Ji Y, Mendonça N, Liu X, Locasale JW, Simpson KW, Duhamel GE, Kersten S, Yates JR, Long Q, Qi L. Sel1L is indispensable for mammalian endoplasmic reticulum-associated degradation, endoplasmic reticulum homeostasis, and survival. Proceedings of the National Academy of Sciences of the United States of America. 111: E582-91. PMID 24453213 DOI: 10.1073/pnas.1318114111  0.44
2014 Sha H, Yang L, Liu M, Xia S, Liu Y, Liu F, Kersten S, Qi L. Adipocyte spliced form of X-box-binding protein 1 promotes adiponectin multimerization and systemic glucose homeostasis. Diabetes. 63: 867-79. PMID 24241534 DOI: 10.2337/db13-1067  0.44
2013 Iwata TN, Cowley TJ, Sloma M, Ji Y, Kim H, Qi L, Lee SS. The transcriptional co-regulator HCF-1 is required for INS-1 β-cell glucose-stimulated insulin secretion. Plos One. 8: e78841. PMID 24250814 DOI: 10.1371/journal.pone.0078841  0.44
2013 Yang L, Sha H, Davisson RL, Qi L. Phenformin activates the unfolded protein response in an AMP-activated protein kinase (AMPK)-dependent manner. The Journal of Biological Chemistry. 288: 13631-8. PMID 23548904 DOI: 10.1074/jbc.M113.462762  0.44
2013 Yang M, Yang L, Qi L, Guo Y, Lin X, Zhang Y, Du Y. Association between the methionine synthase A2756G polymorphism and neural tube defect risk: a meta-analysis. Gene. 520: 7-13. PMID 23438943 DOI: 10.1016/j.gene.2013.02.005  0.44
2013 Stanya KJ, Jacobi D, Liu S, Bhargava P, Dai L, Gangl MR, Inouye K, Barlow JL, Ji Y, Mizgerd JP, Qi L, Shi H, McKenzie AN, Lee CH. Direct control of hepatic glucose production by interleukin-13 in mice. The Journal of Clinical Investigation. 123: 261-71. PMID 23257358 DOI: 10.1172/JCI64941  0.44
2012 He Y, Beatty A, Han X, Ji Y, Ma X, Adelstein RS, Yates JR, Kemphues K, Qi L. Nonmuscle myosin IIB links cytoskeleton to IRE1α signaling during ER stress. Developmental Cell. 23: 1141-52. PMID 23237951 DOI: 10.1016/j.devcel.2012.11.006  0.44
2012 Ji Y, Sun S, Xia S, Yang L, Li X, Qi L. Short term high fat diet challenge promotes alternative macrophage polarization in adipose tissue via natural killer T cells and interleukin-4. The Journal of Biological Chemistry. 287: 24378-86. PMID 22645141 DOI: 10.1074/jbc.M112.371807  0.44
2012 Sun S, Xia S, Ji Y, Kersten S, Qi L. The ATP-P2X7 signaling axis is dispensable for obesity-associated inflammasome activation in adipose tissue. Diabetes. 61: 1471-8. PMID 22415881 DOI: 10.2337/db11-1389  0.44
2012 Sun S, Ji Y, Kersten S, Qi L. Mechanisms of inflammatory responses in obese adipose tissue. Annual Review of Nutrition. 32: 261-86. PMID 22404118 DOI: 10.1146/annurev-nutr-071811-150623  0.44
2012 Ji Y, Sun S, Xu A, Bhargava P, Yang L, Lam KS, Gao B, Lee CH, Kersten S, Qi L. Activation of natural killer T cells promotes M2 Macrophage polarization in adipose tissue and improves systemic glucose tolerance via interleukin-4 (IL-4)/STAT6 protein signaling axis in obesity. The Journal of Biological Chemistry. 287: 13561-71. PMID 22396530 DOI: 10.1074/jbc.M112.350066  0.44
2011 Sha H, He Y, Yang L, Qi L. Stressed out about obesity: IRE1α-XBP1 in metabolic disorders. Trends in Endocrinology and Metabolism: Tem. 22: 374-81. PMID 21703863 DOI: 10.1016/j.tem.2011.05.002  0.44
2011 Xia S, Sha H, Yang L, Ji Y, Ostrand-Rosenberg S, Qi L. Gr-1+ CD11b+ myeloid-derived suppressor cells suppress inflammation and promote insulin sensitivity in obesity. The Journal of Biological Chemistry. 286: 23591-9. PMID 21592961 DOI: 10.1074/jbc.M111.237123  0.44
2011 Francisco AB, Singh R, Sha H, Yan X, Qi L, Lei X, Long Q. Haploid insufficiency of suppressor enhancer Lin12 1-like (SEL1L) protein predisposes mice to high fat diet-induced hyperglycemia. The Journal of Biological Chemistry. 286: 22275-82. PMID 21536682 DOI: 10.1074/jbc.M111.239418  0.44
2011 Qi L, Yang L, Chen H. Detecting and quantitating physiological endoplasmic reticulum stress. Methods in Enzymology. 490: 137-46. PMID 21266248 DOI: 10.1016/B978-0-12-385114-7.00008-8  0.44
2010 Lichtenstein L, Mattijssen F, de Wit NJ, Georgiadi A, Hooiveld GJ, van der Meer R, He Y, Qi L, Köster A, Tamsma JT, Tan NS, Müller M, Kersten S. Angptl4 protects against severe proinflammatory effects of saturated fat by inhibiting fatty acid uptake into mesenteric lymph node macrophages. Cell Metabolism. 12: 580-92. PMID 21109191 DOI: 10.1016/j.cmet.2010.11.002  0.44
2010 He Y, Sun S, Sha H, Liu Z, Yang L, Xue Z, Chen H, Qi L. Emerging roles for XBP1, a sUPeR transcription factor. Gene Expression. 15: 13-25. PMID 21061914  0.44
2010 Yang L, Xue Z, He Y, Sun S, Chen H, Qi L. A Phos-tag-based approach reveals the extent of physiological endoplasmic reticulum stress. Plos One. 5: e11621. PMID 20661282 DOI: 10.1371/journal.pone.0011621  0.44
2010 Zeng L, Liu YP, Sha H, Chen H, Qi L, Smith JA. XBP-1 couples endoplasmic reticulum stress to augmented IFN-beta induction via a cis-acting enhancer in macrophages. Journal of Immunology (Baltimore, Md. : 1950). 185: 2324-30. PMID 20660350 DOI: 10.4049/jimmunol.0903052  0.44
2010 Francisco AB, Singh R, Li S, Vani AK, Yang L, Munroe RJ, Diaferia G, Cardano M, Biunno I, Qi L, Schimenti JC, Long Q. Deficiency of suppressor enhancer Lin12 1 like (SEL1L) in mice leads to systemic endoplasmic reticulum stress and embryonic lethality. The Journal of Biological Chemistry. 285: 13694-703. PMID 20197277 DOI: 10.1074/jbc.M109.085340  0.44
2009 Sha H, He Y, Chen H, Wang C, Zenno A, Shi H, Yang X, Zhang X, Qi L. The IRE1alpha-XBP1 pathway of the unfolded protein response is required for adipogenesis. Cell Metabolism. 9: 556-64. PMID 19490910 DOI: 10.1016/j.cmet.2009.04.009  0.44
2009 Qi L, Saberi M, Zmuda E, Wang Y, Altarejos J, Zhang X, Dentin R, Hedrick S, Bandyopadhyay G, Hai T, Olefsky J, Montminy M. Adipocyte CREB promotes insulin resistance in obesity. Cell Metabolism. 9: 277-86. PMID 19254572 DOI: 10.1016/j.cmet.2009.01.006  0.44
2006 Qi L, Heredia JE, Altarejos JY, Screaton R, Goebel N, Niessen S, Macleod IX, Liew CW, Kulkarni RN, Bain J, Newgard C, Nelson M, Evans RM, Yates J, Montminy M. TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism. Science (New York, N.Y.). 312: 1763-6. PMID 16794074 DOI: 10.1126/science.1123374  0.44
2005 Koo SH, Flechner L, Qi L, Zhang X, Screaton RA, Jeffries S, Hedrick S, Xu W, Boussouar F, Brindle P, Takemori H, Montminy M. The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism. Nature. 437: 1109-11. PMID 16148943 DOI: 10.1038/nature03967  0.44
2005 Qi L, Strong MA, Karim BO, Huso DL, Greider CW. Telomere fusion to chromosome breaks reduces oncogenic translocations and tumour formation. Nature Cell Biology. 7: 706-11. PMID 15965466 DOI: 10.1038/ncb1276  0.44
2004 Dolan BP, Phelan TP, Ilkovitch D, Qi L, Wade WF, Laufer TM, Ostrand-Rosenberg S. Invariant chain and the MHC class II cytoplasmic domains regulate localization of MHC class II molecules to lipid rafts in tumor cell-based vaccines. Journal of Immunology (Baltimore, Md. : 1950). 172: 907-14. PMID 14707062  1
2003 Qi L, Strong MA, Karim BO, Armanios M, Huso DL, Greider CW. Short telomeres and ataxia-telangiectasia mutated deficiency cooperatively increase telomere dysfunction and suppress tumorigenesis. Cancer Research. 63: 8188-96. PMID 14678974  0.44
2001 Qi L, Ostrand-Rosenberg S. H2-O inhibits presentation of bacterial superantigens, but not endogenous self antigens. Journal of Immunology (Baltimore, Md. : 1950). 167: 1371-8. PMID 11466355  1
2000 Qi L, Ostrand-Rosenberg S. MHC class II presentation of endogenous tumor antigen by cellular vaccines depends on the endocytic pathway but not H2-M. Traffic (Copenhagen, Denmark). 1: 152-60. PMID 11208095  1
2000 Qi L, Rojas JM, Ostrand-Rosenberg S. Tumor cells present MHC class II-restricted nuclear and mitochondrial antigens and are the predominant antigen presenting cells in vivo. Journal of Immunology (Baltimore, Md. : 1950). 165: 5451-61. PMID 11067897  1
1999 Ostrand-Rosenberg S, Pulaski BA, Clements VK, Qi L, Pipeling MR, Hanyok LA. Cell-based vaccines for the stimulation of immunity to metastatic cancers. Immunological Reviews. 170: 101-14. PMID 10566145 DOI: 10.1111/j.1600-065X.1999.tb01332.x  1
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