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Gregory W. Konat - Publications

Affiliations: 
School of Medicine West Virginia University, Morgantown, WV, United States 
Area:
Neuroscience Biology, Molecular Biology, Biochemistry
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38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Petrisko TJ, Konat GW. Peripheral viral challenge increases c-fos level in cerebral neurons. Metabolic Brain Disease. PMID 34406561 DOI: 10.1007/s11011-021-00819-z  0.743
2020 Petrisko TJ, Bloemer J, Pinky PD, Srinivas S, Heslin RT, Du Y, Setti SE, Hong H, Suppiramaniam V, Konat GW, Reed MN. Neuronal CXCL10/CXCR3 Axis Mediates the Induction of Cerebral Hyperexcitability by Peripheral Viral Challenge. Frontiers in Neuroscience. 14: 220. PMID 32265633 DOI: 10.3389/Fnins.2020.00220  0.757
2019 Petrisko TJ, Konat GW. Peripheral viral challenge exacerbates experimental autoimmune encephalomyelitis. Metabolic Brain Disease. PMID 30637619 DOI: 10.1007/S11011-019-0383-Y  0.736
2017 Petrisko T, Konat G. Peripheral viral challenge triggers hippocampal production of inflammatory proteins. Metabolic Brain Disease. 32: 1249-1254. PMID 28523567 DOI: 10.1007/S11011-017-0030-4  0.759
2017 Hunsberger HC, Konat GW, Reed MN. Peripheral viral challenge elevates extracellular glutamate in the hippocampus leading to seizure hypersusceptibility. Journal of Neurochemistry. PMID 28244106 DOI: 10.1111/Jnc.13999  0.393
2016 Hunsberger HC, Wang D, Petrisko TJ, Alhowail A, Setti SE, Suppiramaniam V, Konat GW, Reed MN. Peripherally restricted viral challenge elevates extracellular glutamate and enhances synaptic transmission in the hippocampus. Journal of Neurochemistry. PMID 27168075 DOI: 10.1111/Jnc.13665  0.742
2015 Konat G. Cerebral Response to Peripheral Challenge with a Viral Mimetic. Neurochemical Research. 41: 144-55. PMID 26526143 DOI: 10.1007/S11064-015-1746-3  0.374
2015 Michalovicz LT, Lally B, Konat GW. Peripheral challenge with a viral mimic upregulates expression of the complement genes in the hippocampus. Journal of Neuroimmunology. 285: 137-42. PMID 26198930 DOI: 10.1016/J.Jneuroim.2015.06.003  0.74
2014 Michalovicz LT, Konat GW. Peripherally restricted acute phase response to a viral mimic alters hippocampal gene expression. Metabolic Brain Disease. 29: 75-86. PMID 24363211 DOI: 10.1007/S11011-013-9471-6  0.744
2013 Borysiewicz E, Doppalapudi S, Kirschman LT, Konat GW. TLR3 ligation protects human astrocytes against oxidative stress Journal of Neuroimmunology. 255: 54-59. PMID 23245579 DOI: 10.1016/J.Jneuroim.2012.11.002  0.351
2011 Konat GW, Lally BE, Toth AA, Salm AK. Peripheral immune challenge with viral mimic during early postnatal period robustly enhances anxiety-like behavior in young adult rats. Metabolic Brain Disease. 26: 237-40. PMID 21643765 DOI: 10.1007/S11011-011-9244-Z  0.311
2011 Kirschman LT, Borysiewicz E, Fil D, Konat GW. Peripheral immune challenge with dsRNA enhances kainic acid-induced status epilepticus. Metabolic Brain Disease. 26: 91-3. PMID 21305346 DOI: 10.1007/S11011-011-9236-Z  0.368
2011 Fil D, Borysiewicz E, Konat GW. A broad upregulation of cerebral chemokine genes by peripherally-generated inflammatory mediators. Metabolic Brain Disease. 26: 49-59. PMID 21258854 DOI: 10.1007/S11011-010-9231-9  0.365
2009 Borysiewicz E, Fil D, Dlaboga D, O'Donnell JM, Konat GW. Phosphodiesterase 4B2 gene is an effector of Toll-like receptor signaling in astrocytes. Metabolic Brain Disease. 24: 481-91. PMID 19728060 DOI: 10.1007/S11011-009-9150-9  0.336
2009 Konat GW, Borysiewicz E, Fil D, James I. Peripheral challenge with double-stranded RNA elicits global up-regulation of cytokine gene expression in the brain. Journal of Neuroscience Research. 87: 1381-8. PMID 19115408 DOI: 10.1002/Jnr.21958  0.383
2009 Borysiewicz E, Fil D, Konat GW. Rho proteins are negative regulators of TLR2, TLR3, and TLR4 signaling in astrocytes. Journal of Neuroscience Research. 87: 1565-72. PMID 19115402 DOI: 10.1002/Jnr.21968  0.343
2008 Konat GW, Krasowska-Zoladek A, Kraszpulski M. Statins enhance toll-like receptor 4-mediated cytokine gene expression in astrocytes: implication of Rho proteins in negative feedback regulation. Journal of Neuroscience Research. 86: 603-9. PMID 17896797 DOI: 10.1002/Jnr.21509  0.344
2007 Wiltshire T, Senft J, Wang Y, Konat GW, Wenger SL, Reed E, Wang W. BRCA1 contributes to cell cycle arrest and chemoresistance in response to the anticancer agent irofulven. Molecular Pharmacology. 71: 1051-60. PMID 17229870 DOI: 10.1124/Mol.106.029504  0.319
2006 Banaszewska M, Konat GW. Nucleotides induce higher order chromatin degradation. Molecular and Cellular Biochemistry. 282: 39-43. PMID 16317510 DOI: 10.1007/S11010-006-1154-8  0.392
2004 Krasowska A, Konat GW. Vulnerability of brain tissue to inflammatory oxidant, hypochlorous acid. Brain Research. 997: 176-84. PMID 14706870 DOI: 10.1016/J.Brainres.2003.09.080  0.349
2003 Konat GW. H2O2-induced higher order chromatin degradation: a novel mechanism of oxidative genotoxicity. Journal of Biosciences. 28: 57-60. PMID 12682425 DOI: 10.1007/Bf02970132  0.361
2003 Konat GW, Kofke WA, Miric S. Toxicity of compound A to C6 rat glioma cells. Metabolic Brain Disease. 18: 11-5. PMID 12603078 DOI: 10.1023/A:1021922500998  0.307
2003 Bai H, Konat GW. Hydrogen peroxide mediates higher order chromatin degradation Neurochemistry International. 42: 123-129. PMID 12421592 DOI: 10.1016/S0197-0186(02)00072-4  0.399
2002 Konat GW. Higher order chromatin degradation: implications for neurodegeneration. Neurochemical Research. 27: 1447-51. PMID 12512948 DOI: 10.1023/A:1021688119574  0.373
2001 LoPresti P, Konat GW. Hydrogen peroxide induces transient dephosphorylation of tau protein in cultured rat oligodendrocytes Neuroscience Letters. 311: 142-144. PMID 11567798 DOI: 10.1016/S0304-3940(01)02137-1  0.35
2001 Konat GW, Mouzannar R, Bai H. Higher order chromatin degradation in glial cells: the role of calcium. Neurochemistry International. 39: 179-86. PMID 11434975 DOI: 10.1016/S0197-0186(01)00030-4  0.7
2001 Mouzannar R, Miric SJ, Wiggins RC, Konat GW. Hydrogen peroxide induces rapid digestion of oligodendrocyte chromatin into high molecular weight fragments. Neurochemistry International. 38: 9-15. PMID 10913683 DOI: 10.1016/S0197-0186(00)00066-8  0.704
1999 Royland JE, Konat GW, Wiggins RC. Differentiation dependent activation of the myelin genes in purified oligodendrocytes is highly resistant to hypoglycemia Metabolic Brain Disease. 14: 189-195. PMID 10646694 DOI: 10.1023/A:1020614809546  0.353
1999 Laszkiewicz I, Mouzannar R, Wiggins RC, Konat GW. Delayed oligodendrocyte degeneration induced by brief exposure to hydrogen peroxide. Journal of Neuroscience Research. 55: 303-10. PMID 10348661 DOI: 10.1002/(Sici)1097-4547(19990201)55:3<303::Aid-Jnr5>3.0.Co;2-C  0.721
1997 Gu J, Royland JE, Wiggins RC, Konat GW. Selenium is required for normal upregulation of myelin genes in differentiating oligodendrocytes Journal of Neuroscience Research. 47: 626-635. PMID 9089211 DOI: 10.1002/(Sici)1097-4547(19970315)47:6<626::Aid-Jnr8>3.0.Co;2-F  0.361
1994 Yassini PR, Stickler DL, Bloomfield SM, Wiggins RC, Konat GW. Glioma-stimulated chemoattraction of endothelial cells and fibroblasts in vitro: a model for the study of glioma-induced angiogenesis Metabolic Brain Disease. 9: 391-399. PMID 7534866 DOI: 10.1007/Bf02098885  0.327
1994 Zhu W, Wiggins RC, Konat GW. Glucocorticoid‐induced upregulation of proteolipid protein and myelin‐associated glycoprotein genes in C6 cells Journal of Neuroscience Research. 37: 208-212. PMID 7512149 DOI: 10.1002/Jnr.490370206  0.369
1993 Royland JE, Konat G, Wiggins RC. Abnormal upregulation of myelin genes underlies the critical period of myelination in undernourished developing rat brain. Brain Research. 607: 113-6. PMID 7683238 DOI: 10.1016/0006-8993(93)91495-E  0.349
1993 Yassini PR, Wiggins RC, Konat GW. Spatiotemporal expression of SCIP and myelin genes in rat brain during early postnatal development Developmental Neuroscience. 15: 128-132. PMID 7513278 DOI: 10.1159/000111325  0.358
1993 Royland JE, Konat GW, Wiggins RC. Myelin gene activation: A glucose sensitive critical period in development Journal of Neuroscience Research. 36: 399-404. PMID 7505839 DOI: 10.1002/Jnr.490360406  0.317
1992 Royland J, Konat GW, Kanoh M, Wiggins RC. Down regulation of myelin-specific mRNAs in the mechanism of hypomyelination in the undernourisched developing brain Developmental Brain Research. 65: 223-226. PMID 1373995 DOI: 10.1016/0165-3806(92)90183-W  0.342
1992 Kanoh M, Wiggins RC, Konat G. Differential upregulation of PLP and MAG genes in C6 glioma cells by N2A neuroblastoma conditioned medium. Metabolic Brain Disease. 7: 147-156. PMID 1279370 DOI: 10.1007/Bf01000160  0.376
1991 Kanoh M, Ye P, Zhu W, Wiggins RC, Konat G. Effect of culture conditions on PLP and MAG gene expression in rat glioma C6 cells. Metabolic Brain Disease. 6: 133-143. PMID 1723486 DOI: 10.1007/Bf00996905  0.378
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