| Year |
Citation |
Score |
| 2020 |
Torti SV, Torti FM. Iron and cancer: 2020 Vision. Cancer Research. PMID 32928919 DOI: 10.1158/0008-5472.Can-20-2017 |
0.483 |
|
| 2020 |
Torti SV, Torti FM. Iron: The cancer connection. Molecular Aspects of Medicine. 100860. PMID 32340745 DOI: 10.1016/J.Mam.2020.100860 |
0.453 |
|
| 2020 |
Konstorum A, Tesfay L, Paul BT, Torti FM, Laubenbacher RC, Torti SV. Systems biology of ferroptosis: A modeling approach. Journal of Theoretical Biology. 110222. PMID 32114023 DOI: 10.1016/J.Jtbi.2020.110222 |
0.352 |
|
| 2019 |
Paul BT, Tesfay L, Winkler CR, Torti FM, Torti SV. Sideroflexin 4 affects Fe-S cluster biogenesis, iron metabolism, mitochondrial respiration and heme biosynthetic enzymes. Scientific Reports. 9: 19634. PMID 31873120 DOI: 10.1038/S41598-019-55907-Z |
0.348 |
|
| 2019 |
Tesfay L, Paul BT, Konstorum A, Deng Z, Cox AO, Lee J, Furdui CM, Hegde P, Torti FM, Torti SV. Steroyl-CoA Desaturase 1 (SCD1) protects ovarian cancer cells from ferroptotic cell death. Cancer Research. PMID 31270077 DOI: 10.1158/0008-5472.Can-19-0369 |
0.37 |
|
| 2019 |
Moghieb A, Tesfay L, Nie S, Gritsenko M, Fillmore TL, Jacobs JM, Smith RD, Torti FM, Torti SV, Shi T, Ansong C. A Targeted Mass Spectrometric Assay for Reliable Sensitive Hepcidin Quantification. Scientific Reports. 9: 7264. PMID 31086210 DOI: 10.1038/S41598-019-43756-9 |
0.329 |
|
| 2019 |
Torti SV, Torti FM. Winning the war with iron. Nature Nanotechnology. PMID 30911165 DOI: 10.1038/S41565-019-0419-9 |
0.392 |
|
| 2019 |
Vieira LS, Masison J, Adams J, Torti S, Laubenbacher R, Chifman J. Abstract 2442: Assessing how macrophages attain distinct iron handling phenotypes in a tumor via a mathematical model Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-2442 |
0.371 |
|
| 2018 |
Torti SV, Manz DH, Paul BT, Blanchette-Farra N, Torti FM. Iron and Cancer. Annual Review of Nutrition. 38: 97-125. PMID 30130469 DOI: 10.1146/Annurev-Nutr-082117-051732 |
0.484 |
|
| 2018 |
Konstorum A, Lynch ML, Torti SV, Torti FM, Laubenbacher RC. A Systems Biology Approach to Understanding the Pathophysiology of High-Grade Serous Ovarian Cancer: Focus on Iron and Fatty Acid Metabolism. Omics : a Journal of Integrative Biology. 22: 502-513. PMID 30004845 DOI: 10.1089/Omi.2018.0060 |
0.453 |
|
| 2018 |
Blanchette-Farra N, Kita D, Konstorum A, Tesfay L, Lemler D, Hegde P, Claffey KP, Torti FM, Torti SV. Contribution of three-dimensional architecture and tumor-associated fibroblasts to hepcidin regulation in breast cancer. Oncogene. PMID 29695834 DOI: 10.1038/S41388-018-0243-Y |
0.413 |
|
| 2018 |
Chang G, Li J, Wang B, Yamamoto Y, Mahalingam R, Duleba M, Rao W, Xie J, Wang S, Jazaeri A, Davies P, Torti S, Draetta G, Anderson M, Brewer M, et al. Abstract B05: Cloning and vulnerability of intrinsically resistant subset of ovarian cancer stem cells Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Ovca17-B05 |
0.318 |
|
| 2018 |
Konstorum A, Lynch ML, Torti SV, Torti FM, Laubenbacher RC. Abstract 1322: A systems-level approach identifies novel links between iron and fatty acid metabolism in high-grade serous ovarian cancer Cancer Research. 78: 1322-1322. DOI: 10.1158/1538-7445.Am2018-1322 |
0.435 |
|
| 2017 |
Deng Z, Manz DH, Torti SV, Torti FM. Iron-responsive element-binding protein 2 plays an essential role in regulating prostate cancer cell growth. Oncotarget. 8: 82231-82243. PMID 29137259 DOI: 10.18632/Oncotarget.19288 |
0.43 |
|
| 2017 |
Deng Z, Manz DH, Torti S, Torti FM. Effects of ferroportin-mediated iron depletion in cells representative of different histological subtypes of prostate cancer. Antioxidants & Redox Signaling. PMID 29061069 DOI: 10.1089/Ars.2017.7023 |
0.407 |
|
| 2017 |
Stockwell BR, Friedmann Angeli JP, Bayir H, Bush AI, Conrad M, Dixon SJ, Fulda S, Gascón S, Hatzios SK, Kagan VE, Noel K, Jiang X, Linkermann A, Murphy ME, Overholtzer M, ... ... Torti SV, et al. Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease. Cell. 171: 273-285. PMID 28985560 DOI: 10.1016/J.Cell.2017.09.021 |
0.355 |
|
| 2017 |
Deng Z, Manz DH, Torti SV, Torti FM. Iron-responsive element-binding protein 2 plays an essential role in regulating prostate cancer cell growth. Oncotarget. PMID 28751622 DOI: 10.18632/oncotarget.19288 |
0.319 |
|
| 2017 |
Basuli D, Tesfay L, Deng Z, Paul B, Yamamoto Y, Ning G, Xian W, McKeon F, Lynch M, Crum CP, Hegde P, Brewer M, Wang X, Miller LD, Dyment N, ... ... Torti SV, et al. Iron addiction: a novel therapeutic target in ovarian cancer. Oncogene. PMID 28319068 DOI: 10.1038/Onc.2017.11 |
0.479 |
|
| 2017 |
Lemler DJ, Lynch ML, Tesfay L, Deng Z, Paul BT, Wang X, Hegde P, Manz DH, Torti SV, Torti FM. DCYTB is a predictor of outcome in breast cancer that functions via iron-independent mechanisms. Breast Cancer Research : Bcr. 19: 25. PMID 28270217 DOI: 10.1186/S13058-017-0814-9 |
0.418 |
|
| 2017 |
Chifman J, Arat S, Deng Z, Lemler E, Pino JC, Harris LA, Kochen MA, Lopez CF, Akman SA, Torti FM, Torti SV, Laubenbacher R. Activated Oncogenic Pathway Modifies Iron Network in Breast Epithelial Cells: A Dynamic Modeling Perspective. Plos Computational Biology. 13: e1005352. PMID 28166223 DOI: 10.1371/Journal.Pcbi.1005352 |
0.466 |
|
| 2017 |
Paul B, Lynch M, Torti F, Torti S. Abstract 1501: Sideroflexin4: A novel regulator of iron metabolism in ovarian cancer Cancer Research. 77: 1501-1501. DOI: 10.1158/1538-7445.Am2017-1501 |
0.409 |
|
| 2016 |
Paul BT, Manz DH, Torti FM, Torti SV. Mitochondria and Iron: Current Questions. Expert Review of Hematology. PMID 27911100 DOI: 10.1080/17474086.2016.1268047 |
0.414 |
|
| 2016 |
Manz DH, Blanchette NL, Paul BT, Torti FM, Torti SV. Iron and cancer: recent insights. Annals of the New York Academy of Sciences. PMID 26890363 DOI: 10.1111/Nyas.13008 |
0.49 |
|
| 2016 |
Blanchette NL, Manz DH, Torti FM, Torti SV. Modulation of hepcidin to treat iron deregulation: potential clinical applications. Expert Review of Hematology. 9: 169-86. PMID 26669208 DOI: 10.1586/17474086.2016.1124757 |
0.406 |
|
| 2015 |
Yamamoto Y, Ning G, Howitt BE, Mehra K, Wu L, Wang X, Hong Y, Kern F, Wei TS, Zhang T, Nagarajan N, Basuli D, Torti S, Brewer M, Choolani M, et al. In Vitro and In Vivo Correlates of Physiologic and Neoplastic Human Fallopian Tube Stem Cells. The Journal of Pathology. PMID 26415052 DOI: 10.1002/Path.4649 |
0.309 |
|
| 2015 |
Hatcher HC, Tesfay L, Torti SV, Torti FM. Cytoprotective Effect of Ferritin H in Renal Ischemia Reperfusion Injury. Plos One. 10: e0138505. PMID 26379029 DOI: 10.1371/Journal.Pone.0138505 |
0.364 |
|
| 2015 |
Swanner J, Mims J, Carroll DL, Akman SA, Furdui CM, Torti SV, Singh RN. Differential cytotoxic and radiosensitizing effects of silver nanoparticles on triple-negative breast cancer and non-triple-negative breast cells. International Journal of Nanomedicine. 10: 3937-53. PMID 26185437 DOI: 10.2147/Ijn.S80349 |
0.358 |
|
| 2015 |
Tesfay L, Clausen KA, Kim JW, Hegde P, Wang X, Miller LD, Deng Z, Blanchette N, Arvedson T, Miranti CK, Babitt JL, Lin HY, Peehl DM, Torti FM, Torti SV. Hepcidin regulation in prostate and its disruption in prostate cancer. Cancer Research. 75: 2254-63. PMID 25858146 DOI: 10.1158/0008-5472.Can-14-2465 |
0.317 |
|
| 2015 |
Chakradeo S, Sharma K, Alhaddad A, Bakhshwin D, Le N, Harada H, Nakajima W, Yeudall WA, Torti SV, Torti FM, Gewirtz DA. Yet another function of p53--the switch that determines whether radiation-induced autophagy will be cytoprotective or nonprotective: implications for autophagy inhibition as a therapeutic strategy. Molecular Pharmacology. 87: 803-14. PMID 25667224 DOI: 10.1124/Mol.114.095273 |
0.328 |
|
| 2015 |
Ning G, Yamamoto Y, Zhang T, Wang X, Wilson L, Torti S, Brewer M, Crum C, McKeon F, Xian W. Abstract POSTER-TECH-1121: Rapid identification and targeting of chemotherapy-resistant tumor stem cell clones in ovarian cancer Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Ovcasymp14-Poster-Tech-1121 |
0.333 |
|
| 2015 |
Chakradeo S, Sharma K, Alhaddad A, Bakhshwin D, Le N, Harada H, Yeudall WA, Torti S, Torti F, Gewirtz D. Abstract 998: Induction of non-protective autophagy by radiation in tumor cells: Implications for autophagy inhibition as a therapeutic strategy Cancer Research. 75: 998-998. DOI: 10.1158/1538-7445.Am2015-998 |
0.352 |
|
| 2015 |
Zhang T, Ning G, Yamamoto Y, Howitt B, Wang X, Wilson L, Hong Y, Khor CC, Torti S, Brewer M, Crum C, McKeon F, Xian W. Abstract 4223: Rapid identification and targeting of chemotherapy resistant tumor stem cell clones in ovarian high-grade serous carcinoma Cancer Research. 75: 4223-4223. DOI: 10.1158/1538-7445.Am2015-4223 |
0.328 |
|
| 2015 |
Sharma K, Thekkudan T, Gewirtz D, Harada H, Torti F, Torti S. Abstract 1013: Understanding the molecular pathways underlying radio-sensitization of non-small cell lung cancer (NSCLC) by vitamin D (EB1089) Cancer Research. 75: 1013-1013. DOI: 10.1158/1538-7445.Am2015-1013 |
0.307 |
|
| 2014 |
Chifman J, Laubenbacher R, Torti SV. A systems biology approach to iron metabolism. Advances in Experimental Medicine and Biology. 844: 201-25. PMID 25480643 DOI: 10.1007/978-1-4939-2095-2_10 |
0.405 |
|
| 2014 |
Basuli D, Stevens RG, Torti FM, Torti SV. Epidemiological associations between iron and cardiovascular disease and diabetes. Frontiers in Pharmacology. 5: 117. PMID 24904420 DOI: 10.3389/Fphar.2014.00117 |
0.398 |
|
| 2014 |
Wang W, Deng Z, Hatcher H, Miller LD, Di X, Tesfay L, Sui G, D'Agostino RB, Torti FM, Torti SV. IRP2 regulates breast tumor growth. Cancer Research. 74: 497-507. PMID 24285726 DOI: 10.1158/0008-5472.Can-13-1224 |
0.443 |
|
| 2013 |
Torti SV, Torti FM. Cellular iron metabolism in prognosis and therapy of breast cancer. Critical Reviews in Oncogenesis. 18: 435-48. PMID 23879588 DOI: 10.1615/Critrevoncog.2013007784 |
0.456 |
|
| 2013 |
Xie Z, Harrison SH, Torti SV, Torti FM, Han J. Application of circuit simulation method for differential modeling of TIM-2 iron uptake and metabolism in mouse kidney cells. Frontiers in Physiology. 4: 136. PMID 23761763 DOI: 10.3389/Fphys.2013.00136 |
0.393 |
|
| 2013 |
Wang W, Grier DD, Woo J, Ward M, Sui G, Torti SV, Torti FM, Beaty MW. Ferritin H is a novel marker of early erythroid precursors and macrophages. Histopathology. 62: 931-40. PMID 23611361 DOI: 10.1111/His.12101 |
0.44 |
|
| 2013 |
Torti SV, Torti FM. Iron and cancer: more ore to be mined. Nature Reviews. Cancer. 13: 342-55. PMID 23594855 DOI: 10.1038/Nrc3495 |
0.461 |
|
| 2012 |
Burke AR, Singh RN, Carroll DL, Torti FM, Torti SV. Targeting Cancer Stem Cells with Nanoparticle-Enabled Therapies. Journal of Molecular Biomarkers & Diagnosis. PMID 24383043 DOI: 10.4172/2155-9929.S8-003 |
0.309 |
|
| 2012 |
Tesfay L, Huhn AJ, Hatcher H, Torti FM, Torti SV. Ferritin blocks inhibitory effects of two-chain high molecular weight kininogen (HKa) on adhesion and survival signaling in endothelial cells. Plos One. 7: e40030. PMID 22768328 DOI: 10.1371/Journal.Pone.0040030 |
0.335 |
|
| 2012 |
Wan M, Huang W, Kute TE, Miller LD, Zhang Q, Hatcher H, Wang J, Stovall DB, Russell GB, Cao PD, Deng Z, Wang W, Zhang Q, Lei M, Torti SV, et al. Yin Yang 1 plays an essential role in breast cancer and negatively regulates p27. The American Journal of Pathology. 180: 2120-33. PMID 22440256 DOI: 10.1016/J.Ajpath.2012.01.037 |
0.375 |
|
| 2012 |
Chifman J, Kniss A, Neupane P, Williams I, Leung B, Deng Z, Mendes P, Hower V, Torti FM, Akman SA, Torti SV, Laubenbacher R. The core control system of intracellular iron homeostasis: a mathematical model. Journal of Theoretical Biology. 300: 91-9. PMID 22286016 DOI: 10.1016/J.Jtbi.2012.01.024 |
0.397 |
|
| 2012 |
Burke AR, Singh RN, Carroll DL, Wood JC, D'Agostino RB, Ajayan PM, Torti FM, Torti SV. The resistance of breast cancer stem cells to conventional hyperthermia and their sensitivity to nanoparticle-mediated photothermal therapy. Biomaterials. 33: 2961-70. PMID 22245557 DOI: 10.1016/J.Biomaterials.2011.12.052 |
0.339 |
|
| 2012 |
Clausen KA, Di X, Torti FM, Torti SV. Abstract 3253: Bone morphogenetic proteins increase hepcidin in breast cancer cells Cancer Research. 72: 3253-3253. DOI: 10.1158/1538-7445.Am2012-3253 |
0.464 |
|
| 2011 |
Han J, Seaman WE, Di X, Wang W, Willingham M, Torti FM, Torti SV. Iron uptake mediated by binding of H-ferritin to the TIM-2 receptor in mouse cells. Plos One. 6: e23800. PMID 21886823 DOI: 10.1371/Journal.Pone.0023800 |
0.447 |
|
| 2011 |
Miller LD, Coffman LG, Chou JW, Black MA, Bergh J, D'Agostino R, Torti SV, Torti FM. An iron regulatory gene signature predicts outcome in breast cancer. Cancer Research. 71: 6728-37. PMID 21875943 DOI: 10.1158/0008-5472.Can-11-1870 |
0.725 |
|
| 2011 |
Ding X, Singh R, Burke A, Hatcher H, Olson J, Kraft RA, Schmid M, Carroll D, Bourland JD, Akman S, Torti FM, Torti SV. Development of iron-containing multiwalled carbon nanotubes for MR-guided laser-induced thermotherapy. Nanomedicine (London, England). 6: 1341-52. PMID 21506687 DOI: 10.2217/Nnm.11.37 |
0.34 |
|
| 2011 |
Cortes DF, Sha W, Hower V, Blekherman G, Laubenbacher R, Akman S, Torti SV, Shulaev V. Differential gene expression in normal and transformed human mammary epithelial cells in response to oxidative stress. Free Radical Biology & Medicine. 50: 1565-74. PMID 21397008 DOI: 10.1016/J.Freeradbiomed.2011.03.002 |
0.36 |
|
| 2011 |
Torti SV, Torti FM. Ironing out cancer. Cancer Research. 71: 1511-4. PMID 21363917 DOI: 10.1158/0008-5472.Can-10-3614 |
0.452 |
|
| 2011 |
Clausen KA, Blish KR, Birse CE, Triplette MA, Kute TE, Russell GB, D'Agostino RB, Miller LD, Torti FM, Torti SV. SOSTDC1 differentially modulates Smad and beta-catenin activation and is down-regulated in breast cancer. Breast Cancer Research and Treatment. 129: 737-46. PMID 21113658 DOI: 10.1007/S10549-010-1261-9 |
0.758 |
|
| 2011 |
Miller LD, Coffman LG, Chou JW, Black MA, Bergh J, D'Agostino R, Torti SV, Torti FM. Abstract C64: Iron regulatory gene signature predicts outcome in breast cancer Cancer Research. 71. DOI: 10.1158/1538-7445.Fbcr11-C64 |
0.751 |
|
| 2010 |
Blish KR, Clausen KA, Hawkins GA, Garvin AJ, Willingham MC, Turner JC, Torti FM, Torti SV. Loss of heterozygosity and SOSTDC1 in adult and pediatric renal tumors. Journal of Experimental & Clinical Cancer Research : Cr. 29: 147. PMID 21080955 DOI: 10.1186/1756-9966-29-147 |
0.743 |
|
| 2010 |
Pinnix ZK, Miller LD, Wang W, D'Agostino R, Kute T, Willingham MC, Hatcher H, Tesfay L, Sui G, Di X, Torti SV, Torti FM. Ferroportin and iron regulation in breast cancer progression and prognosis. Science Translational Medicine. 2: 43ra56. PMID 20686179 DOI: 10.1126/Scisignal.3001127 |
0.773 |
|
| 2010 |
Wang W, Di X, Torti SV, Torti FM. Ferritin H induction by histone deacetylase inhibitors. Biochemical Pharmacology. 80: 316-24. PMID 20385107 DOI: 10.1016/J.Bcp.2010.04.008 |
0.418 |
|
| 2010 |
Wang W, Knovich MA, Coffman LG, Torti FM, Torti SV. Serum ferritin: Past, present and future. Biochimica Et Biophysica Acta. 1800: 760-9. PMID 20304033 DOI: 10.1016/J.Bbagen.2010.03.011 |
0.704 |
|
| 2010 |
Li L, Fang CJ, Ryan JC, Niemi EC, Lebrón JA, Björkman PJ, Arase H, Torti FM, Torti SV, Nakamura MC, Seaman WE. Binding and uptake of H-ferritin are mediated by human transferrin receptor-1 Proceedings of the National Academy of Sciences of the United States of America. 107: 3505-3510. PMID 20133674 DOI: 10.1073/Pnas.0913192107 |
0.373 |
|
| 2010 |
Huhn AJ, Parsonage D, Torti SV, Hollis T. Abstract 1285: The effects of the HK5-ferritin interaction and iron on tumor angiogenesis Cancer Research. 70: 1285-1285. DOI: 10.1158/1538-7445.Am10-1285 |
0.399 |
|
| 2010 |
Ding X, Bourland J, Singh R, Burke A, Hatcher H, Olson J, Carroll D, Kraft R, Torti S, Torti F. WE-E-204B-05: MR Relaxation Properties for Fe-Containing MWCNTs and Potential for Combined MR Imaging and Tumor Ablation Therapy Medical Physics. 37: 3438-3438. DOI: 10.1118/1.3469435 |
0.306 |
|
| 2009 |
Hatcher HC, Singh RN, Torti FM, Torti SV. Synthetic and natural iron chelators: therapeutic potential and clinical use. Future Medicinal Chemistry. 1: 1643-70. PMID 21425984 DOI: 10.4155/Fmc.09.121 |
0.439 |
|
| 2009 |
Storey JA, Connor RF, Lewis ZT, Hurd D, Pomper G, Keung YK, Grover M, Lovato J, Torti SV, Torti FM, Molnár I. The transplant iron score as a predictor of stem cell transplant survival. Journal of Hematology & Oncology. 2: 44. PMID 19852846 DOI: 10.1186/1756-8722-2-44 |
0.388 |
|
| 2009 |
Laubenbacher R, Hower V, Jarrah A, Torti SV, Shulaev V, Mendes P, Torti FM, Akman S. A systems biology view of cancer. Biochimica Et Biophysica Acta. 1796: 129-39. PMID 19505535 DOI: 10.1016/J.Bbcan.2009.06.001 |
0.327 |
|
| 2009 |
Hower V, Mendes P, Torti FM, Laubenbacher R, Akman S, Shulaev V, Torti SV. A general map of iron metabolism and tissue-specific subnetworks. Molecular Biosystems. 5: 422-43. PMID 19381358 DOI: 10.1039/B816714C |
0.404 |
|
| 2009 |
Coffman LG, Parsonage D, D'Agostino R, Torti FM, Torti SV. Regulatory effects of ferritin on angiogenesis. Proceedings of the National Academy of Sciences of the United States of America. 106: 570-5. PMID 19126685 DOI: 10.1073/Pnas.0812010106 |
0.72 |
|
| 2009 |
Knovich MA, Storey JA, Coffman LG, Torti SV, Torti FM. Ferritin for the clinician. Blood Reviews. 23: 95-104. PMID 18835072 DOI: 10.1016/J.Blre.2008.08.001 |
0.723 |
|
| 2009 |
Jiao Y, Wilkinson J, Di X, Wang W, Hatcher H, Kock ND, D'Agostino R, Knovich MA, Torti FM, Torti SV. Curcumin, a cancer chemopreventive and chemotherapeutic agent, is a biologically active iron chelator. Blood. 113: 462-9. PMID 18815282 DOI: 10.1182/Blood-2008-05-155952 |
0.449 |
|
| 2008 |
Zhang F, Wang W, Tsuji Y, Torti SV, Torti FM. Post-transcriptional modulation of iron homeostasis during p53-dependent growth arrest. The Journal of Biological Chemistry. 283: 33911-8. PMID 18819919 DOI: 10.1074/Jbc.M806432200 |
0.43 |
|
| 2008 |
Hatcher H, Planalp R, Cho J, Torti FM, Torti SV. Curcumin: From ancient medicine to current clinical trials Cellular and Molecular Life Sciences. 65: 1631-1652. PMID 18324353 DOI: 10.1007/S00018-008-7452-4 |
0.706 |
|
| 2008 |
Coffman LG, Brown JC, Johnson DA, Parthasarathy N, D'Agostino RB, Lively MO, Hua X, Tilley SL, Muller-Esterl W, Willingham MC, Torti FM, Torti SV. Cleavage of high-molecular-weight kininogen by elastase and tryptase is inhibited by ferritin. American Journal of Physiology. Lung Cellular and Molecular Physiology. 294: L505-15. PMID 18192590 DOI: 10.1152/Ajplung.00347.2007 |
0.701 |
|
| 2008 |
Blish KR, Wang W, Willingham MC, Du W, Birse CE, Krishnan SR, Brown JC, Hawkins GA, Garvin AJ, D'Agostino RB, Torti FM, Torti SV. A human bone morphogenetic protein antagonist is down-regulated in renal cancer. Molecular Biology of the Cell. 19: 457-64. PMID 18032587 DOI: 10.1091/Mbc.E07-05-0433 |
0.75 |
|
| 2008 |
Childers ML, Cho J, Regino CA, Brechbiel MW, DiPasquale AG, Rheingold AL, Torti SV, Torti FM, Planalp RP. Influence of ligand structure on Fe(II) spin-state and redox rate in cytotoxic tripodal chelators. Journal of Inorganic Biochemistry. 102: 150-6. PMID 17900698 DOI: 10.1016/J.Jinorgbio.2007.07.039 |
0.672 |
|
| 2007 |
Wang W, Di X, D'Agostino RB, Torti SV, Torti FM. Excess capacity of the iron regulatory protein system. The Journal of Biological Chemistry. 282: 24650-9. PMID 17604281 DOI: 10.1074/Jbc.M703167200 |
0.445 |
|
| 2006 |
Jennings-Gee JE, Tsuji Y, Pietsch EC, Moran E, Mymryk JS, Torti FM, Torti SV. Coordinate inhibition of cytokine-mediated induction of ferritin H, manganese superoxide dismutase, and interleukin-6 by the adenovirus E1A oncogene. The Journal of Biological Chemistry. 281: 16428-35. PMID 16611629 DOI: 10.1074/Jbc.M600038200 |
0.75 |
|
| 2006 |
Jiao Y, Wilkinson J, Christine Pietsch E, Buss JL, Wang W, Planalp R, Torti FM, Torti SV. Iron chelation in the biological activity of curcumin. Free Radical Biology & Medicine. 40: 1152-60. PMID 16545682 DOI: 10.1016/J.Freeradbiomed.2005.11.003 |
0.728 |
|
| 2006 |
Wilkinson J, Di X, Schönig K, Buss JL, Kock ND, Cline JM, Saunders TL, Bujard H, Torti SV, Torti FM. Tissue-specific expression of ferritin H regulates cellular iron homoeostasis in vivo. The Biochemical Journal. 395: 501-7. PMID 16448386 DOI: 10.1042/Bj20060063 |
0.424 |
|
| 2005 |
Regino CA, Torti SV, Ma R, Yap GP, Kreisel KA, Torti FM, Planalp RP, Brechbiel MW. N-picolyl derivatives of Kemp's triamine as potential antitumor agents: a preliminary investigation. Journal of Medicinal Chemistry. 48: 7993-9. PMID 16335923 DOI: 10.1021/Jm050724R |
0.645 |
|
| 2005 |
Chen TT, Li L, Chung DH, Allen CD, Torti SV, Torti FM, Cyster JG, Chen CY, Brodsky FM, Niemi EC, Nakamura MC, Seaman WE, Daws MR. TIM-2 is expressed on B cells and in liver and kidney and is a receptor for H-ferritin endocytosis. The Journal of Experimental Medicine. 202: 955-65. PMID 16203866 DOI: 10.1084/Jem.20042433 |
0.342 |
|
| 2005 |
Torti SV, Ma R, Venditto VJ, Torti FM, Planalp RP, Brechbiel MW. Preliminary evaluation of the cytotoxicity of a series of tris-2-aminoethylamine (Tren) based hexadentate heterocyclic donor agents. Bioorganic & Medicinal Chemistry. 13: 5961-7. PMID 16115775 DOI: 10.1016/J.Bmc.2005.07.007 |
0.655 |
|
| 2005 |
Turner J, Koumenis C, Kute TE, Planalp RP, Brechbiel MW, Beardsley D, Cody B, Brown KD, Torti FM, Torti SV. Tachpyridine, a metal chelator, induces G2 cell-cycle arrest, activates checkpoint kinases, and sensitizes cells to ionizing radiation. Blood. 106: 3191-9. PMID 16014567 DOI: 10.1182/Blood-2005-03-1263 |
0.7 |
|
| 2005 |
Alexander RL, Greene BT, Torti SV, Kucera GL. A novel phospholipid gemcitabine conjugate is able to bypass three drug-resistance mechanisms. Cancer Chemotherapy and Pharmacology. 56: 15-21. PMID 15789226 DOI: 10.1007/S00280-004-0949-0 |
0.734 |
|
| 2005 |
Franks MA, Schrader EA, Pietsch EC, Pennella DR, Torti SV, Welker ME. Oxathiolene oxide synthesis via chelation-controlled addition of organometallic reagents to alkynols followed by addition of sulfur electrophiles and evaluation of oxathiolene oxides as anticarcinogenic enzyme inducers. Bioorganic & Medicinal Chemistry. 13: 2221-33. PMID 15727874 DOI: 10.1016/J.Bmc.2004.12.037 |
0.754 |
|
| 2005 |
Connor R, Molnar I, Lovato J, Grover M, Hurd D, Pomper G, Torti SV, Torti FM. Markers of Iron Overload Are Poor Prognostic Factors in Stem Cell Transplantation. Blood. 106: 5228-5228. DOI: 10.1182/Blood.V106.11.5228.5228 |
0.404 |
|
| 2005 |
Childers ML, Su F, Przyborowska AM, Bishwokarma B, Park G, Brechbiel MW, Torti SV, Torti FM, Broker G, Alexander JS, Rogers RD, Ruhlandt-Senge K, Planalp RP. Pyridine-ring alkylation of cytotoxic r-1,c-3,c-5-tris[(2-pyridylmethyl)- amino]cyclohexane chelators: Structural and electronic properties of the Mn II, FeII, NiII, CuII and Zn II complexes European Journal of Inorganic Chemistry. 3971-3982. DOI: 10.1002/Ejic.200500382 |
0.648 |
|
| 2004 |
Buss JL, Greene BT, Turner J, Torti FM, Torti SV. Iron chelators in cancer chemotherapy. Current Topics in Medicinal Chemistry. 4: 1623-35. PMID 15579100 DOI: 10.2174/1568026043387269 |
0.789 |
|
| 2004 |
Pham CG, Bubici C, Zazzeroni F, Papa S, Jones J, Alvarez K, Jayawardena S, De Smaele E, Cong R, Beaumont C, Torti FM, Torti SV, Franzoso G. Ferritin heavy chain upregulation by NF-kappaB inhibits TNFalpha-induced apoptosis by suppressing reactive oxygen species. Cell. 119: 529-42. PMID 15537542 DOI: 10.1016/J.Cell.2004.10.017 |
0.362 |
|
| 2004 |
Chong HS, Torti SV, Ma R, Torti FM, Brechbiel MW. Synthesis and potent antitumor activities of novel 1,3,5-cis,cis-triaminocyclohexane N-pyridyl derivatives. Journal of Medicinal Chemistry. 47: 5230-4. PMID 15456266 DOI: 10.1021/Jm040076W |
0.372 |
|
| 2004 |
Ye N, Park G, Przyborowska AM, Sloan PE, Clifford T, Bauer CB, Broker GA, Rogers RD, Ma R, Torti SV, Brechbiel MW, Planalp RP. Nickel(II), copper(II) and zinc(II) binding properties and cytotoxicity of tripodal, hexadentate tris(ethylenediamine)--analogue chelators. Dalton Transactions (Cambridge, England : 2003). 1304-11. PMID 15252622 DOI: 10.1039/B403476G |
0.634 |
|
| 2004 |
Zhao R, Planalp RP, Ma R, Greene BT, Jones BT, Brechbiel MW, Torti FM, Torti SV. Role of zinc and iron chelation in apoptosis mediated by tachpyridine, an anti-cancer iron chelator. Biochemical Pharmacology. 67: 1677-88. PMID 15081867 DOI: 10.1016/J.Bcp.2003.12.036 |
0.811 |
|
| 2003 |
Wilkinson J, Pietsch EC, Torti SV, Torti FM. Ferritin regulation by oxidants and chemopreventive xenobiotics. Advances in Enzyme Regulation. 43: 135-51. PMID 12791388 DOI: 10.1016/S0065-2571(02)00037-7 |
0.758 |
|
| 2003 |
Pietsch EC, Hurley AL, Scott EE, Duckworth BP, Welker ME, Leone-Kabler S, Townsend AJ, Torti FM, Torti SV. Oxathiolene oxides: a novel family of compounds that induce ferritin, glutathione S-transferase, and other proteins of the phase II response. Biochemical Pharmacology. 65: 1261-9. PMID 12694867 DOI: 10.1016/S0006-2952(03)00081-9 |
0.769 |
|
| 2003 |
Buss JL, Torti FM, Torti SV. The role of iron chelation in cancer therapy. Current Medicinal Chemistry. 10: 1021-34. PMID 12678674 DOI: 10.2174/0929867033457638 |
0.452 |
|
| 2003 |
Thompson K, Menzies S, Muckenthaler M, Torti FM, Wood T, Torti SV, Hentze MW, Beard J, Connor J. Mouse brains deficient in H-ferritin have normal iron concentration but a protein profile of iron deficiency and increased evidence of oxidative stress. Journal of Neuroscience Research. 71: 46-63. PMID 12478613 DOI: 10.1002/Jnr.10463 |
0.379 |
|
| 2003 |
Pietsch EC, Chan JY, Torti FM, Torti SV. Nrf2 mediates the induction of ferritin H in response to xenobiotics and cancer chemopreventive dithiolethiones. The Journal of Biological Chemistry. 278: 2361-9. PMID 12435735 DOI: 10.1074/Jbc.M210664200 |
0.783 |
|
| 2002 |
Chong HS, Torti FM, Torti SV, Brechbiel MW. Synthesis of 1,3,5-cis,cis-triaminocyclohexane N-pyridyl derivatives as potential antitumor agents. The Journal of Organic Chemistry. 67: 8072-8. PMID 12423134 DOI: 10.1021/Jo0204911 |
0.384 |
|
| 2002 |
Planalp RP, Przyborowska AM, Park G, Ye N, Lu FH, Rogers RD, Broker GA, Torti SV, Brechbiel MW. Novel cytotoxic chelators that bind iron(II) selectively over zinc(II) under aqueous aerobic conditions. Biochemical Society Transactions. 30: 758-62. PMID 12196188 DOI: 10.1042/Bst0300758 |
0.691 |
|
| 2002 |
Torti FM, Torti SV. Regulation of ferritin genes and protein. Blood. 99: 3505-16. PMID 11986201 DOI: 10.1182/Blood.V99.10.3505 |
0.386 |
|
| 2002 |
Greene BT, Thorburn J, Willingham MC, Thorburn A, Planalp RP, Brechbiel MW, Jennings-Gee J, Wilkinson J, Torti FM, Torti SV. Activation of caspase pathways during iron chelator-mediated apoptosis. The Journal of Biological Chemistry. 277: 25568-75. PMID 11980894 DOI: 10.1074/Jbc.M110345200 |
0.779 |
|
| 2001 |
Abeysinghe RD, Greene BT, Haynes R, Willingham MC, Turner J, Planalp RP, Brechbiel MW, Torti FM, Torti SV. p53-independent apoptosis mediated by tachpyridine, an anti-cancer iron chelator. Carcinogenesis. 22: 1607-14. PMID 11576999 DOI: 10.1093/Carcin/22.10.1607 |
0.79 |
|
| 2001 |
Orino K, Lehman L, Tsuji Y, Ayaki H, Torti SV, Torti FM. Ferritin and the response to oxidative stress. The Biochemical Journal. 357: 241-7. PMID 11415455 DOI: 10.1042/0264-6021:3570241 |
0.44 |
|
| 2000 |
Tsuji Y, Ayaki H, Whitman SP, Morrow CS, Torti SV, Torti FM. Coordinate transcriptional and translational regulation of ferritin in response to oxidative stress Molecular and Cellular Biology. 20: 5818-5827. PMID 10913165 DOI: 10.1128/Mcb.20.16.5818-5827.2000 |
0.396 |
|
| 1999 |
Orino K, Tsuji Y, Torti FM, Torti SV. Adenovirus E1A blocks oxidant-dependent ferritin induction and sensitizes cells to pro-oxidant cytotoxicity Febs Letters. 461: 334-338. PMID 10567722 DOI: 10.1016/S0014-5793(99)01443-X |
0.374 |
|
| 1999 |
Tsuji Y, Moran E, Torti SV, Torti M. Transcriptional regulation of the mouse ferritin H gene: Involvement of p300/CBP adaptor proteins in FER-1 enhancer activity Journal of Biological Chemistry. 274: 7501-7507. PMID 10066817 DOI: 10.1074/Jbc.274.11.7501 |
0.335 |
|
| 1998 |
Torti SV, Torti FM, Whitman SP, Brechbiel MW, Park G, Planalp RP. Tumor cell cytotoxicity of a novel metal chelator. Blood. 92: 1384-9. PMID 9694727 DOI: 10.1182/Blood.V92.4.1384.416K30_1384_1389 |
0.682 |
|
| 1998 |
Torti SV, Torti FM. Human H-kininogen is a ferritin-binding protein Journal of Biological Chemistry. 273: 13630-13635. PMID 9593701 DOI: 10.1074/Jbc.273.22.13630 |
0.307 |
|
| 1998 |
Tsuji Y, Torti SV, Torti FM. Activation of the ferritin H enhancer, FER-1, by the cooperative action of members of the AP1 and SP1 transcription factor families Journal of Biological Chemistry. 273: 2984-2992. PMID 9446612 DOI: 10.1074/Jbc.273.5.2984 |
0.306 |
|
| 1998 |
Park G, Lu FH, Ye N, Brechbiel MW, Torti SV, Torti FM, Planalp RP. Novel iron complexes and chelators based on cis, cis-1,3,5- triaminocyclohexane: Iron-mediated ligand oxidation and biochemical properties Journal of Biological Inorganic Chemistry. 3: 449-457. DOI: 10.1007/S007750050254 |
0.7 |
|
| 1996 |
Rucker P, Torti FM, Torti SV. Role of H and L subunits in mouse ferritin Journal of Biological Chemistry. 271: 33352-33357. PMID 8969195 DOI: 10.1074/Jbc.271.52.33352 |
0.333 |
|
| 1995 |
Kwak EL, Larochelle DA, Beaumont C, Torti SV, Torti FM. Role for NF-kappa B in the regulation of ferritin H by tumor necrosis factor-alpha. The Journal of Biological Chemistry. 270: 15285-93. PMID 7797515 DOI: 10.1074/Jbc.270.25.15285 |
0.347 |
|
| 1995 |
Tsuji Y, Akebi N, Lam TK, Nakabeppu Y, Torti SV, Torti FM. FER-1, an enhancer of the ferritin H gene and a target of E1A-mediated transcriptional repression Molecular and Cellular Biology. 15: 5152-5164. PMID 7651432 DOI: 10.1128/Mcb.15.9.5152 |
0.32 |
|
| 1994 |
Torti SV, Torti FM. Iron and ferritin in inflammation and cancer Advances in Inorganic Biochemistry. 10: 119-137. PMID 8203285 |
0.333 |
|
| 1994 |
Torti FM, Torti SV. Cytokines, iron homeostasis, and cancer Advances in Experimental Medicine and Biology. 354: 161-170. PMID 8067284 DOI: 10.1007/978-1-4899-0939-8_12 |
0.451 |
|
| 1993 |
Schröder H, Warren S, Bargetzi MJ, Torti SV, Torti FM. N-acetyl-L-cysteine protects endothelial cells but not L929 tumor cells from tumor necrosis factor-α-mediated cytotoxicity Naunyn-Schmiedeberg's Archives of Pharmacology. 347: 664-666. PMID 8361551 DOI: 10.1007/Bf00166951 |
0.3 |
|
| 1993 |
Warren S, Torti SV, Torti FM. The role of iron in the cytotoxicity of tumor necrosis factor Lymphokine and Cytokine Research. 12: 75-80. PMID 8324080 |
0.334 |
|
| 1993 |
Tsuji Y, Ninomiya-Tsuji J, Torti SV, Torti FM. Selective loss of CDC2 and CDK2 induction by tumor necrosis factor-α in senescent human diploid fibroblasts Experimental Cell Research. 209: 175-182. PMID 8262134 DOI: 10.1006/Excr.1993.1299 |
0.343 |
|
| 1991 |
Miller LL, Miller SC, Torti SV, Tsuji Y, Torti FM. Iron-independent induction of ferritin H chain by tumor necrosis factor Proceedings of the National Academy of Sciences of the United States of America. 88: 4946-4950. PMID 2052577 DOI: 10.1073/Pnas.88.11.4946 |
0.419 |
|
| 1990 |
Wei Y, Miller SC, Tsuji Y, Torti SV, Torti FM. Interleukin 1 induces ferritin heavy chain in human muscle cells Biochemical and Biophysical Research Communications. 169: 289-296. PMID 2350350 DOI: 10.1016/0006-291X(90)91466-6 |
0.321 |
|
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