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John K. Buolamwini - Publications

Affiliations: 
Pharmaceutical Sciences University of Tennessee Health Science Center, Memphis, TN, United States 
Area:
Pharmaceutical Chemistry
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41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Wang C, Buolamwini JK. A novel RNA variant of human concentrative nucleoside transporter 1 (hCNT1) that is a potential cancer biomarker. Experimental Hematology & Oncology. 8: 18. PMID 31440421 DOI: 10.1186/S40164-019-0144-Y  0.352
2015 Nag S, Qin JJ, Voruganti S, Wang MH, Sharma H, Patil S, Buolamwini JK, Wang W, Zhang R. Development and validation of a rapid HPLC method for quantitation of SP-141, a novel pyrido[b]indole anticancer agent, and an initial pharmacokinetic study in mice. Biomedical Chromatography : Bmc. 29: 654-63. PMID 25294254 DOI: 10.1002/Bmc.3327  0.521
2014 Playa H, Lewis TA, Ting A, Suh BC, Muñoz B, Matuza R, Passer BJ, Schreiber SL, Buolamwini JK. Dilazep analogues for the study of equilibrative nucleoside transporters 1 and 2 (ENT1 and ENT2). Bioorganic & Medicinal Chemistry Letters. 24: 5801-4. PMID 25454272 DOI: 10.1016/J.Bmcl.2014.10.026  0.486
2014 Wang W, Qin JJ, Voruganti S, Srivenugopal KS, Nag S, Patil S, Sharma H, Wang MH, Wang H, Buolamwini JK, Zhang R. The pyrido[b]indole MDM2 inhibitor SP-141 exerts potent therapeutic effects in breast cancer models. Nature Communications. 5: 5086. PMID 25271708 DOI: 10.1038/Ncomms6086  0.6
2014 Wang W, Qin JJ, Voruganti S, Wang MH, Sharma H, Patil S, Zhou J, Wang H, Mukhopadhyay D, Buolamwini JK, Zhang R. Identification of a new class of MDM2 inhibitor that inhibits growth of orthotopic pancreatic tumors in mice. Gastroenterology. 147: 893-902.e2. PMID 25016295 DOI: 10.1053/J.Gastro.2014.07.001  0.596
2014 Sun S, Playa HC, Deokar HS, Lin W, Buolamwini JK. Abstract 4478: Biopharmaceutic studies of novel nucleoside transporter inhibitor prodrugs that can protect against nucleoside drug-induced mitochondrial toxicity Cancer Research. 74: 4478-4478. DOI: 10.1158/1538-7445.Am2014-4478  0.546
2013 Chen Q, Buolamwini JK, Smith JC, Li A, Xu Q, Cheng X, Wei D. Impact of resistance mutations on inhibitor binding to HIV-1 integrase. Journal of Chemical Information and Modeling. 53: 3297-307. PMID 24205814 DOI: 10.1021/Ci400537N  0.317
2013 Sharma H, Sanchez TW, Neamati N, Detorio M, Schinazi RF, Cheng X, Buolamwini JK. Synthesis, docking, and biological studies of phenanthrene β-diketo acids as novel HIV-1 integrase inhibitors. Bioorganic & Medicinal Chemistry Letters. 23: 6146-51. PMID 24091080 DOI: 10.1016/J.Bmcl.2013.09.009  0.619
2013 Wang C, Lin W, Playa H, Sun S, Cameron K, Buolamwini JK. Dipyridamole analogs as pharmacological inhibitors of equilibrative nucleoside transporters. Identification of novel potent and selective inhibitors of the adenosine transporter function of human equilibrative nucleoside transporter 4 (hENT4). Biochemical Pharmacology. 86: 1531-40. PMID 24021350 DOI: 10.1016/J.Bcp.2013.08.063  0.652
2013 Lu C, Liu D, Jin J, Deokar H, Zhang Y, Buolamwini JK, Yu X, Yan C, Chen X. Inhibition of gastric tumor growth by a novel Hsp90 inhibitor. Biochemical Pharmacology. 85: 1246-56. PMID 23415900 DOI: 10.1016/J.Bcp.2013.02.003  0.38
2012 Yang X, Wang W, Qin JJ, Wang MH, Sharma H, Buolamwini JK, Wang H, Zhang R. JKA97, a novel benzylidene analog of harmine, exerts anti-cancer effects by inducing G1 arrest, apoptosis, and p53-independent up-regulation of p21. Plos One. 7: e34303. PMID 22558087 DOI: 10.1371/Journal.Pone.0034303  0.567
2012 Sharma H, Cheng X, Buolamwini JK. Homology model-guided 3D-QSAR studies of HIV-1 integrase inhibitors. Journal of Chemical Information and Modeling. 52: 515-44. PMID 22256860 DOI: 10.1021/Ci200485A  0.613
2012 Wang W, Yang X, Zhang X, Wang M, Sharma H, Buolamwini JK, Zhang R. Abstract 3834: JKA97, a novel anti-cancer candidate, induces G1 arrest via up-regulation of p21 in a p53-independent manner Cancer Research. 72: 3834-3834. DOI: 10.1158/1538-7445.Am2012-3834  0.559
2011 Lin W, Buolamwini JK. Design, synthesis, and evaluation of 2-diethanolamino-4,8-diheptamethyleneimino-2-(N-aminoethyl-N-ethanolamino)-6-(N,N-diethanolamino)pyrimido[5,4-d]pyrimidine-fluorescein conjugate (8MDP-fluor), as a novel equilibrative nucleoside transporter probe. Bioconjugate Chemistry. 22: 1221-7. PMID 21539390 DOI: 10.1021/Bc2000758  0.556
2011 Sharma H, Patil S, Sanchez TW, Neamati N, Schinazi RF, Buolamwini JK. Synthesis, biological evaluation and 3D-QSAR studies of 3-keto salicylic acid chalcones and related amides as novel HIV-1 integrase inhibitors. Bioorganic & Medicinal Chemistry. 19: 2030-45. PMID 21371895 DOI: 10.1016/J.Bmc.2011.01.047  0.612
2011 Wang H, Ma X, Ren S, Buolamwini JK, Yan C. A small-molecule inhibitor of MDMX activates p53 and induces apoptosis. Molecular Cancer Therapeutics. 10: 69-79. PMID 21075910 DOI: 10.1158/1535-7163.Mct-10-0581  0.385
2010 Passer BJ, Cheema T, Zhou B, Wakimoto H, Zaupa C, Razmjoo M, Sarte J, Wu S, Wu CL, Noah JW, Li Q, Buolamwini JK, Yen Y, Rabkin SD, Martuza RL. Identification of the ENT1 antagonists dipyridamole and dilazep as amplifiers of oncolytic herpes simplex virus-1 replication. Cancer Research. 70: 3890-5. PMID 20424118 DOI: 10.1158/0008-5472.Can-10-0155  0.379
2010 Wang C, Pimple S, Buolamwini JK. Interaction of benzopyranone derivatives and related compounds with human concentrative nucleoside transporters 1, 2 and 3 heterologously expressed in porcine PK15 nucleoside transporter deficient cells. Structure-activity relationships and determinants of transporter affinity and selectivity. Biochemical Pharmacology. 79: 307-20. PMID 19735647 DOI: 10.1016/J.Bcp.2009.08.028  0.514
2009 Okamura T, Singh S, Buolamwini J, Haystead T, Friedman H, Bigner D, Ali-Osman F. Tyrosine phosphorylation of the human glutathione S-transferase P1 by epidermal growth factor receptor. The Journal of Biological Chemistry. 284: 16979-89. PMID 19254954 DOI: 10.1074/Jbc.M808153200  0.319
2009 Gupte A, Buolamwini JK. Synthesis and biological evaluation of phloridzin analogs as human concentrative nucleoside transporter 3 (hCNT3) inhibitors. Bioorganic & Medicinal Chemistry Letters. 19: 917-21. PMID 19097778 DOI: 10.1016/J.Bmcl.2008.11.112  0.71
2009 Gupte A, Buolamwini JK. CoMFA and CoMSIA 3D-QSAR studies on S(6)-(4-nitrobenzyl)mercaptopurine riboside (NBMPR) analogs as inhibitors of human equilibrative nucleoside transporter 1 (hENT1). Bioorganic & Medicinal Chemistry Letters. 19: 314-8. PMID 19091561 DOI: 10.1016/J.Bmcl.2008.11.092  0.694
2008 Hevener KE, Ball DM, Buolamwini JK, Lee RE. Quantitative structure-activity relationship studies on nitrofuranyl anti-tubercular agents. Bioorganic & Medicinal Chemistry. 16: 8042-53. PMID 18701298 DOI: 10.1016/J.Bmc.2008.07.070  0.392
2008 Zhu Z, Buolamwini JK. Constrained NBMPR analogue synthesis, pharmacophore mapping and 3D-QSAR modeling of equilibrative nucleoside transporter 1 (ENT1) inhibitory activity. Bioorganic & Medicinal Chemistry. 16: 3848-65. PMID 18289860 DOI: 10.1016/J.Bmc.2008.01.044  0.636
2008 Luo W, Liu J, Li J, Zhang D, Liu M, Addo JK, Patil S, Zhang L, Yu J, Buolamwini JK, Chen J, Huang C. Anti-cancer effects of JKA97 are associated with its induction of cell apoptosis via a Bax-dependent and p53-independent pathway. The Journal of Biological Chemistry. 283: 8624-33. PMID 18218619 DOI: 10.1074/Jbc.M707860200  0.382
2007 Gupte A, Buolamwini JK. Novel C2-purine position analogs of nitrobenzylmercaptopurine riboside as human equilibrative nucleoside transporter 1 inhibitors. Bioorganic & Medicinal Chemistry. 15: 7726-37. PMID 17881236 DOI: 10.1016/J.Bmc.2007.08.058  0.706
2007 Lin W, Buolamwini JK. Synthesis, flow cytometric evaluation, and identification of highly potent dipyridamole analogues as equilibrative nucleoside transporter 1 inhibitors. Journal of Medicinal Chemistry. 50: 3906-20. PMID 17636949 DOI: 10.1021/Jm070311L  0.645
2007 Zhu Z, Hofmann PA, Buolamwini JK. Cardioprotective effects of novel tetrahydroisoquinoline analogs of nitrobenzylmercaptopurine riboside in an isolated perfused rat heart model of acute myocardial infarction. American Journal of Physiology. Heart and Circulatory Physiology. 292: H2921-6. PMID 17293492 DOI: 10.1152/ajpheart.01191.2005  0.535
2007 Patil S, Kamath S, Sanchez T, Neamati N, Schinazi RF, Buolamwini JK. Synthesis and biological evaluation of novel 5(H)-phenanthridin-6-ones, 5(H)-phenanthridin-6-one diketo acid, and polycyclic aromatic diketo acid analogs as new HIV-1 integrase inhibitors. Bioorganic & Medicinal Chemistry. 15: 1212-28. PMID 17158051 DOI: 10.1016/J.Bmc.2006.11.026  0.406
2006 Kamath S, Buolamwini JK. Targeting EGFR and HER-2 receptor tyrosine kinases for cancer drug discovery and development. Medicinal Research Reviews. 26: 569-94. PMID 16788977 DOI: 10.1002/Med.20070  0.31
2005 Gupte A, Buolamwini JK, Yadav V, Chu CK, Naguib FN, el Kouni MH. 6-Benzylthioinosine analogues: promising anti-toxoplasmic agents as inhibitors of the mammalian nucleoside transporter ENT1 (es). Biochemical Pharmacology. 71: 69-73. PMID 16310172 DOI: 10.1016/J.Bcp.2005.10.031  0.686
2005 Buolamwini JK, Addo J, Kamath S, Patil S, Mason D, Ores M. Small molecule antagonists of the MDM2 oncoprotein as anticancer agents. Current Cancer Drug Targets. 5: 57-68. PMID 15720190 DOI: 10.2174/1568009053332672  0.427
2004 Addo JK, Buolamwini JK. Design, synthesis, and evaluation of 5'-S-aminoethyl-N(6)- azidobenzyl-5'-thioadenosine biotin conjugate: a bifunctional photoaffinity probe for the es nucleoside transporter. Bioconjugate Chemistry. 15: 536-40. PMID 15149181 DOI: 10.1021/Bc034165J  0.425
2004 Gupte A, Buolamwini JK. Novel halogenated nitrobenzylthioinosine analogs as es nucleoside transporter inhibitors. Bioorganic & Medicinal Chemistry Letters. 14: 2257-60. PMID 15081020 DOI: 10.1016/J.Bmcl.2004.02.016  0.718
2004 Kuo CL, Assefa H, Kamath S, Brzozowski Z, Slawinski J, Saczewski F, Buolamwini JK, Neamati N. Application of CoMFA and CoMSIA 3D-QSAR and docking studies in optimization of mercaptobenzenesulfonamides as HIV-1 integrase inhibitors. Journal of Medicinal Chemistry. 47: 385-99. PMID 14711310 DOI: 10.1021/Jm030378I  0.419
2003 Assefa H, Kamath S, Buolamwini JK. 3D-QSAR and docking studies on 4-anilinoquinazoline and 4-anilinoquinoline epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors. Journal of Computer-Aided Molecular Design. 17: 475-93. PMID 14703120 DOI: 10.1023/B:Jcam.0000004622.13865.4F  0.343
2003 Kamath S, Buolamwini JK. Receptor-guided alignment-based comparative 3D-QSAR studies of benzylidene malonitrile tyrphostins as EGFR and HER-2 kinase inhibitors. Journal of Medicinal Chemistry. 46: 4657-68. PMID 14561085 DOI: 10.1021/Jm030065N  0.397
2003 Zhu Z, Furr J, Buolamwini JK. Synthesis and flow cytometric evaluation of novel 1,2,3,4-tetrahydroisoquinoline conformationally constrained analogues of nitrobenzylmercaptopurine riboside (NBMPR) designed for probing its conformation when bound to the es nucleoside transporter. Journal of Medicinal Chemistry. 46: 831-7. PMID 12593662 DOI: 10.1021/Jm020405P  0.647
2002 Buolamwini JK, Assefa H. CoMFA and CoMSIA 3D QSAR and docking studies on conformationally-restrained cinnamoyl HIV-1 integrase inhibitors: exploration of a binding mode at the active site. Journal of Medicinal Chemistry. 45: 841-52. PMID 11831895 DOI: 10.1021/Jm010399H  0.404
2001 Wang H, Prasad G, Buolamwini JK, Zhang R. Antisense anticancer oligonucleotide therapeutics. Current Cancer Drug Targets. 1: 177-196. PMID 12188878 DOI: 10.2174/1568009013334133  0.302
1999 Raghavan K, Kahn SD, Buolamwini JK. Building a hypothesis for nucleotide transport inhibitors Acs Symposium Series. 719: 153-164.  0.391
1997 Buolamwini JK. Nucleoside transport inhibitors: Structure-activity relationships and potential therapeutic applications Current Medicinal Chemistry. 4: 35-66.  0.407
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