Keith A. Hoffmaster, Ph.D. - Publications

Affiliations: 
2004 University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Pharmacology, Pharmaceutical Chemistry

16 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 L'Italien LE, Orozco O, Abrams TJ, Cantagallo L, Connor A, Desai J, Ebersbach H, Gelderblom H, Hoffmaster K, Lees E, Maacke H, Schleyer S, Skegro D, Lee-Hoeflich ST. Mechanistic insights of an immunological adverse event induced by an anti-KIT antibody drug conjugate and mitigation strategies. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29615457 DOI: 10.1158/1078-0432.Ccr-17-3786  0.306
2016 Ersoy BA, Hoffmaster KA. Drug transporters Principles of Pharmacology: the Pathophysiologic Basis of Drug Therapy: Fourth Edition 0.312
2014 Barnes-Seeman D, Boiselle C, Capacci-Daniel C, Chopra R, Hoffmaster K, Jones CT, Kato M, Lin K, Ma S, Pan G, Shu L, Wang J, Whiteman L, Xu M, Zheng R, et al. Design and synthesis of lactam-thiophene carboxylic acids as potent hepatitis C virus polymerase inhibitors. Bioorganic & Medicinal Chemistry Letters. 24: 3979-85. PMID 24986660 DOI: 10.1016/J.Bmcl.2014.06.031  0.327
2013 Brouwer KL, Keppler D, Hoffmaster KA, Bow DA, Cheng Y, Lai Y, Palm JE, Stieger B, Evers R. In vitro methods to support transporter evaluation in drug discovery and development. Clinical Pharmacology and Therapeutics. 94: 95-112. PMID 23588315 DOI: 10.1038/Clpt.2013.81  0.628
2012 Zamek-Gliszczynski MJ, Hoffmaster KA, Tweedie DJ, Giacomini KM, Hillgren KM. Highlights from the international transporter consortium second workshop Clinical Pharmacology and Therapeutics. 92: 553-556. PMID 23085880 DOI: 10.1038/Clpt.2012.126  0.656
2011 Wang QY, Bushell S, Qing M, Xu HY, Bonavia A, Nunes S, Zhou J, Poh MK, Florez de Sessions P, Niyomrattanakit P, Dong H, Hoffmaster K, Goh A, Nilar S, Schul W, et al. Inhibition of dengue virus through suppression of host pyrimidine biosynthesis. Journal of Virology. 85: 6548-56. PMID 21507975 DOI: 10.1128/Jvi.02510-10  0.303
2010 Giacomini KM, Huang SM, Tweedie DJ, Benet LZ, Brouwer KL, Chu X, Dahlin A, Evers R, Fischer V, Hillgren KM, Hoffmaster KA, Ishikawa T, Keppler D, Kim RB, et al. Membrane transporters in drug development. Nature Reviews. Drug Discovery. 9: 215-36. PMID 20190787 DOI: 10.1038/Nrd3028  0.711
2009 Dash A, Inman W, Hoffmaster K, Sevidal S, Kelly J, Obach RS, Griffith LG, Tannenbaum SR. Liver tissue engineering in the evaluation of drug safety. Expert Opinion On Drug Metabolism & Toxicology. 5: 1159-74. PMID 19637986 DOI: 10.1517/17425250903160664  0.439
2008 Zamek-Gliszczynski MJ, Hoffmaster KA, Nezasa K, Brouwer KL. Apparent differences in mechanisms of harmol sulfate biliary excretion in mice and rats. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 2156-8. PMID 18719241 DOI: 10.1124/Dmd.108.022053  0.752
2006 Zamek-Gliszczynski MJ, Hoffmaster KA, Humphreys JE, Tian X, Nezasa K, Brouwer KL. Differential involvement of Mrp2 (Abcc2) and Bcrp (Abcg2) in biliary excretion of 4-methylumbelliferyl glucuronide and sulfate in the rat. The Journal of Pharmacology and Experimental Therapeutics. 319: 459-67. PMID 16857726 DOI: 10.1124/Jpet.106.101840  0.774
2006 Turncliff RZ, Hoffmaster KA, Kalvass JC, Pollack GM, Brouwer KL. Hepatobiliary disposition of a drug/metabolite pair: Comprehensive pharmacokinetic modeling in sandwich-cultured rat hepatocytes. The Journal of Pharmacology and Experimental Therapeutics. 318: 881-9. PMID 16690724 DOI: 10.1124/Jpet.106.102616  0.741
2006 Zamek-Gliszczynski MJ, Hoffmaster KA, Nezasa K, Tallman MN, Brouwer KL. Integration of hepatic drug transporters and phase II metabolizing enzymes: mechanisms of hepatic excretion of sulfate, glucuronide, and glutathione metabolites. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 27: 447-86. PMID 16472997 DOI: 10.1016/J.Ejps.2005.12.007  0.735
2005 Zamek-Gliszczynski MJ, Hoffmaster KA, Tian X, Zhao R, Polli JW, Humphreys JE, Webster LO, Bridges AS, Kalvass JC, Brouwer KL. Multiple mechanisms are involved in the biliary excretion of acetaminophen sulfate in the rat: role of Mrp2 and Bcrp1. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 33: 1158-65. PMID 15860656 DOI: 10.1124/Dmd.104.002188  0.763
2005 Hoffmaster KA, Zamek-Gliszczynski MJ, Pollack GM, Brouwer KL. Multiple transport systems mediate the hepatic uptake and biliary excretion of the metabolically stable opioid peptide [D-penicillamine2,5]enkephalin. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 33: 287-93. PMID 15528320 DOI: 10.1124/Dmd.104.001420  0.77
2004 Hoffmaster KA, Zamek-Gliszczynski MJ, Pollack GM, Brouwer KL. Hepatobiliary disposition of the metabolically stable opioid peptide [D-Pen2, D-Pen5]-enkephalin (DPDPE): pharmacokinetic consequences of the interplay between multiple transport systems. The Journal of Pharmacology and Experimental Therapeutics. 311: 1203-10. PMID 15302892 DOI: 10.1124/Jpet.104.070201  0.768
2004 Hoffmaster KA, Turncliff RZ, LeCluyse EL, Kim RB, Meier PJ, Brouwer KL. P-glycoprotein expression, localization, and function in sandwich-cultured primary rat and human hepatocytes: relevance to the hepatobiliary disposition of a model opioid peptide. Pharmaceutical Research. 21: 1294-302. PMID 15290872 DOI: 10.1023/B:Pham.0000033018.97745.0D  0.735
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