Heidi Scrable - Publications

Affiliations: 
University of Virginia, Charlottesville, VA 
Area:
Neuroscience Biology, Genetics, Molecular Biology

30 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Pehar M, Ko MH, Li M, Scrable H, Puglielli L. P44, the 'longevity-assurance' isoform of P53, regulates tau phosphorylation and is activated in an age-dependent fashion. Aging Cell. 13: 449-56. PMID 24341977 DOI: 10.1111/Acel.12192  0.462
2014 Takahashi R, Markovic SN, Scrable HJ. Dominant effects of Δ40p53 on p53 function and melanoma cell fate. The Journal of Investigative Dermatology. 134: 791-800. PMID 24037342 DOI: 10.1038/jid.2013.391  0.444
2013 Stevenson M, Carlisle R, Davies B, Preece C, Hammett M, Liu WL, Fisher KD, Ryan A, Scrable H, Seymour LW. Development of a Positive-readout Mouse Model of siRNA Pharmacodynamics. Molecular Therapy. Nucleic Acids. 2: e133. PMID 24253258 DOI: 10.1038/Mtna.2013.63  0.333
2013 Gambino V, De Michele G, Venezia O, Migliaccio P, Dall'Olio V, Bernard L, Minardi SP, Della Fazia MA, Bartoli D, Servillo G, Alcalay M, Luzi L, Giorgio M, Scrable H, Pelicci PG, et al. Oxidative stress activates a specific p53 transcriptional response that regulates cellular senescence and aging. Aging Cell. 12: 435-45. PMID 23448364 DOI: 10.1111/acel.12060  0.38
2013 Takahashi R, Giannini C, Sarkaria JN, Schroeder M, Rogers J, Mastroeni D, Scrable H. p53 isoform profiling in glioblastoma and injured brain. Oncogene. 32: 3165-74. PMID 22824800 DOI: 10.1038/Onc.2012.322  0.496
2013 Zhang P, Ungewitter E, Appella E, Scrable H. Abstract LB-121: Tumor suppressor p53 is involved in a CHAMP-dependent spindle assembly checkpoint pathway. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Lb-121  0.712
2011 Hinault C, Kawamori D, Liew CW, Maier B, Hu J, Keller SR, Mirmira RG, Scrable H, Kulkarni RN. Δ40 Isoform of p53 controls β-cell proliferation and glucose homeostasis in mice. Diabetes. 60: 1210-22. PMID 21357466 DOI: 10.2337/Db09-1379  0.496
2010 Ungewitter E, Scrable H. Delta40p53 controls the switch from pluripotency to differentiation by regulating IGF signaling in ESCs. Genes & Development. 24: 2408-19. PMID 21041409 DOI: 10.1101/Gad.1987810  0.723
2010 Tchkonia T, Morbeck DE, Von Zglinicki T, Van Deursen J, Lustgarten J, Scrable H, Khosla S, Jensen MD, Kirkland JL. Fat tissue, aging, and cellular senescence. Aging Cell. 9: 667-84. PMID 20701600 DOI: 10.1111/J.1474-9726.2010.00608.X  0.353
2010 Pehar M, O'Riordan KJ, Burns-Cusato M, Andrzejewski ME, del Alcazar CG, Burger C, Scrable H, Puglielli L. Altered longevity-assurance activity of p53:p44 in the mouse causes memory loss, neurodegeneration and premature death. Aging Cell. 9: 174-90. PMID 20409077 DOI: 10.1111/J.1474-9726.2010.00547.X  0.499
2009 Scrable H, Burns-Cusato M, Medrano S. Anxiety and the aging brain: stressed out over p53? Biochimica Et Biophysica Acta. 1790: 1587-91. PMID 19800395 DOI: 10.1016/J.Bbagen.2009.09.007  0.401
2009 Ungewitter E, Scrable H. Antagonistic pleiotropy and p53. Mechanisms of Ageing and Development. 130: 10-7. PMID 18639575 DOI: 10.1016/J.Mad.2008.06.002  0.726
2009 Scrable H, Medrano S, Ungewitter E. Running on empty: how p53 controls INS/IGF signaling and affects life span. Experimental Gerontology. 44: 93-100. PMID 18598747 DOI: 10.1016/J.Exger.2008.05.017  0.734
2009 Li H, Costantini C, Scrable H, Weindruch R, Puglielli L. Egr-1 and Hipk2 are required for the TrkA to p75(NTR) switch that occurs downstream of IGF1-R. Neurobiology of Aging. 30: 2010-20. PMID 18378044 DOI: 10.1016/J.Neurobiolaging.2008.02.015  0.474
2009 Medrano S, Burns-Cusato M, Atienza MB, Rahimi D, Scrable H. Regenerative capacity of neural precursors in the adult mammalian brain is under the control of p53. Neurobiology of Aging. 30: 483-97. PMID 17850928 DOI: 10.1016/J.Neurobiolaging.2007.07.016  0.52
2008 Sasaki T, Maier B, Koclega KD, Chruszcz M, Gluba W, Stukenberg PT, Minor W, Scrable H. Phosphorylation regulates SIRT1 function. Plos One. 3: e4020. PMID 19107194 DOI: 10.1371/Journal.Pone.0004020  0.545
2008 Ryan A, Scrable H. Mutant alleles of HD improve the life span of p53(-/-) mice. Mechanisms of Ageing and Development. 129: 238-41. PMID 18242663 DOI: 10.1016/J.Mad.2007.12.003  0.438
2006 Ryan AB, Zeitlin SO, Scrable H. Genetic interaction between expanded murine Hdh alleles and p53 reveal deleterious effects of p53 on Huntington's disease pathogenesis. Neurobiology of Disease. 24: 419-27. PMID 16978870 DOI: 10.1016/J.Nbd.2006.08.002  0.48
2006 Sasaki T, Maier B, Bartke A, Scrable H. Progressive loss of SIRT1 with cell cycle withdrawal. Aging Cell. 5: 413-22. PMID 16939484 DOI: 10.1111/J.1474-9726.2006.00235.X  0.583
2006 Costantini C, Scrable H, Puglielli L. An aging pathway controls the TrkA to p75NTR receptor switch and amyloid beta-peptide generation. The Embo Journal. 25: 1997-2006. PMID 16619032 DOI: 10.1038/Sj.Emboj.7601062  0.462
2005 Medrano S, Scrable H. Maintaining appearances--the role of p53 in adult neurogenesis. Biochemical and Biophysical Research Communications. 331: 828-33. PMID 15865938 DOI: 10.1016/J.Bbrc.2005.03.194  0.404
2005 Scrable H, Sasaki T, Maier B. DeltaNp53 or p44: priming the p53 pump. The International Journal of Biochemistry & Cell Biology. 37: 913-9. PMID 15743665 DOI: 10.1016/J.Biocel.2004.11.014  0.63
2004 Ryan A, Scrable H. Visualization of the dynamics of gene expression in the living mouse. Molecular Imaging. 3: 33-42. PMID 15142410 DOI: 10.1162/153535004773861705  0.366
2004 Maier B, Gluba W, Bernier B, Turner T, Mohammad K, Guise T, Sutherland A, Thorner M, Scrable H. Modulation of mammalian life span by the short isoform of p53. Genes & Development. 18: 306-19. PMID 14871929 DOI: 10.1101/Gad.1162404  0.537
2003 Cronin CA, Ryan AB, Talley EM, Scrable H. Tyrosinase expression during neuroblast divisions affects later pathfinding by retinal ganglion cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 11692-7. PMID 14684871 DOI: 10.1523/Jneurosci.23-37-11692.2003  0.651
2003 Maier B, Medrano S, Sleight SB, Visconti PE, Scrable H. Developmental association of the synaptic activity-regulated protein arc with the mouse acrosomal organelle and the sperm tail. Biology of Reproduction. 68: 67-76. PMID 12493697 DOI: 10.1095/Biolreprod.102.004143  0.327
2002 Scrable H. Say when: reversible control of gene expression in the mouse by lac. Seminars in Cell & Developmental Biology. 13: 109-19. PMID 12127144 DOI: 10.1016/S1084-9521(02)00017-4  0.371
2001 Cronin CA, Gluba W, Scrable H. The lac operator-repressor system is functional in the mouse. Genes & Development. 15: 1506-17. PMID 11410531 DOI: 10.1101/Gad.892001  0.667
1992 Liu HS, Scrable H, Villaret DB, Lieberman MA, Stambrook PJ. Control of Ha-ras-mediated Mammalian Cell Transformation by Escherichia coli Regulatory Elements Cancer Research. 52: 983-989. PMID 1737361  0.321
1990 Mulligan LM, Matlashewski GJ, Scrable HJ, Cavenee WK. Mechanisms of p53 loss in human sarcomas Proceedings of the National Academy of Sciences of the United States of America. 87: 5863-5867. PMID 2143022 DOI: 10.1073/pnas.87.15.5863  0.378
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