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Claire Townsend, Ph.D. - Publications

Affiliations: 
GlaxoSmithKline, Collegeville, PA, United States 
Area:
Drug Development, ion channels
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8 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Townsend C, Brown BS. Predicting drug-induced QT prolongation and torsades de pointes: a review of preclinical endpoint measures. Current Protocols in Pharmacology / Editorial Board, S.J. Enna (Editor-in-Chief) ... [Et Al.]. Unit 10.16. PMID 23744708 DOI: 10.1002/0471141755.Ph1016S61  0.335
2013 Gillie DJ, Novick SJ, Donovan BT, Payne LA, Townsend C. Development of a high-throughput electrophysiological assay for the human ether-à-go-go related potassium channel hERG. Journal of Pharmacological and Toxicological Methods. 67: 33-44. PMID 23103595 DOI: 10.1016/J.Vascn.2012.10.002  0.365
2012 Gillie DJ, Novick SJ, Donovan BT, Payne LA, Townsend C. Development and Validation of a high-throughput Structure-Activity Relationship Assay for the hERG Potassium Channel Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2011.11.1808  0.323
2007 Dale TJ, Townsend C, Hollands EC, Trezise DJ. Population patch clamp electrophysiology: a breakthrough technology for ion channel screening. Molecular Biosystems. 3: 714-22. PMID 17882333 DOI: 10.1039/B706152H  0.354
2004 Peat AJ, Townsend C, Craig McKay M, Garrido D, Terry CM, Wilson JL, Thomson SA. 3-trifluoromethyl-4-nitro-5-arylpyrazoles are novel K(ATP) channel agonists. Bioorganic & Medicinal Chemistry Letters. 14: 813-6. PMID 14741296 DOI: 10.1016/J.Bmcl.2003.10.066  0.342
2002 Peat AJ, Townsend C, Worley JF, Allen SH, Garrido D, Mertz RJ, Pfohl JL, Terry CM, Truax JF, Veasey RL, Thomson SA. Synthesis and evaluation of 7-substituted-3-cyclobutylamino-4H-1,2,4-benzothiadiazine-1,1-dioxide derivatives as K(ATP) channel agonists. Bioorganic & Medicinal Chemistry Letters. 12: 2977-80. PMID 12270187 DOI: 10.1016/S0960-894X(02)00617-0  0.332
1995 Townsend C, Rosenberg RL. Characterization of a chloride channel reconstituted from cardiac sarcoplasmic reticulum. The Journal of Membrane Biology. 147: 121-36. PMID 8568849 DOI: 10.1007/BF00233541  0.48
1993 Wang Y, Townsend C, Rosenberg RL. Regulation of cardiac L-type Ca channels in planar lipid bilayers by G proteins and protein phosphorylation. The American Journal of Physiology. 264: C1473-9. PMID 8392796 DOI: 10.1152/Ajpcell.1993.264.6.C1473  0.469
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