| Year |
Citation |
Score |
| 2015 |
Suri C, Joshi HC, Naik PK. Molecular modeling reveals binding interface of γ-tubulin with GCP4 and interactions with noscapinoids. Proteins. 83: 827-43. PMID 25662919 DOI: 10.1002/Prot.24773 |
0.412 |
|
| 2014 |
Suri C, Hendrickson TW, Joshi HC, Naik PK. Molecular insight into γ-γ tubulin lateral interactions within the γ-tubulin ring complex (γ-TuRC). Journal of Computer-Aided Molecular Design. 28: 961-72. PMID 25031076 DOI: 10.1007/S10822-014-9779-2 |
0.732 |
|
| 2013 |
Qi Q, Liu X, Li S, Joshi HC, Ye K. Synergistic suppression of noscapine and conventional chemotherapeutics on human glioblastoma cell growth. Acta Pharmacologica Sinica. 34: 930-8. PMID 23708557 DOI: 10.1038/Aps.2013.40 |
0.351 |
|
| 2013 |
Ajeawung NF, Joshi HC, Kamnasaran D. The microtubule binding drug EM011 inhibits the growth of paediatric low grade gliomas. Cancer Letters. 335: 109-18. PMID 23402815 DOI: 10.1016/J.Canlet.2013.02.004 |
0.403 |
|
| 2012 |
Li S, He J, Li S, Cao G, Tang S, Tong Q, Joshi HC. Noscapine induced apoptosis via downregulation of survivin in human neuroblastoma cells having wild type or null p53. Plos One. 7: e40076. PMID 22848370 DOI: 10.1371/Journal.Pone.0040076 |
0.381 |
|
| 2012 |
Naik PK, Lopus M, Aneja R, Vangapandu SN, Joshi HC. In silico inspired design and synthesis of a novel tubulin-binding anti-cancer drug: folate conjugated noscapine (Targetin). Journal of Computer-Aided Molecular Design. 26: 233-47. PMID 22170255 DOI: 10.1007/S10822-011-9508-Z |
0.396 |
|
| 2012 |
Li S, Ghaleb AM, He J, Bughani U, Bialkowska AB, Yang VW, Joshi HC. Chemoprevention of familial adenomatous polyposis by bromo-noscapine (EM011) in the Apc(Min/+) mouse model. International Journal of Cancer. 131: 1435-44. PMID 22052467 DOI: 10.1002/Ijc.27344 |
0.378 |
|
| 2012 |
Naik PK, Santoshi S, Joshi HC. Noscapinoids with anti-cancer activity against human acute lymphoblastic leukemia cells (CEM): a three dimensional chemical space pharmacophore modeling and electronic feature analysis. Journal of Molecular Modeling. 18: 307-18. PMID 21523542 DOI: 10.1007/S00894-011-1057-9 |
0.326 |
|
| 2011 |
Santoshi S, Naik PK, Joshi HC. Rational design of novel anti-microtubule agent (9-azido-noscapine) from quantitative structure activity relationship (QSAR) evaluation of noscapinoids. Journal of Biomolecular Screening. 16: 1047-58. PMID 21972248 DOI: 10.1177/1087057111418654 |
0.315 |
|
| 2011 |
Naik PK, Chatterji BP, Vangapandu SN, Aneja R, Chandra R, Kanteveri S, Joshi HC. Rational design, synthesis and biological evaluations of amino-noscapine: a high affinity tubulin-binding noscapinoid. Journal of Computer-Aided Molecular Design. 25: 443-54. PMID 21544622 DOI: 10.1007/S10822-011-9430-4 |
0.327 |
|
| 2011 |
Karna P, Rida PC, Pannu V, Gupta KK, Dalton WB, Joshi H, Yang VW, Zhou J, Aneja R. A novel microtubule-modulating noscapinoid triggers apoptosis by inducing spindle multipolarity via centrosome amplification and declustering. Cell Death and Differentiation. 18: 632-44. PMID 21052096 DOI: 10.1038/Cdd.2010.133 |
0.478 |
|
| 2010 |
Aneja R, Miyagi T, Karna P, Ezell T, Shukla D, Vij Gupta M, Yates C, Chinni SR, Zhau H, Chung LW, Joshi HC. A novel microtubule-modulating agent induces mitochondrially driven caspase-dependent apoptosis via mitotic checkpoint activation in human prostate cancer cells. European Journal of Cancer (Oxford, England : 1990). 46: 1668-78. PMID 20303260 DOI: 10.1016/J.Ejca.2010.02.017 |
0.348 |
|
| 2010 |
Aneja R, Asress S, Dhiman N, Awasthi A, Rida PC, Arora SK, Zhou J, Glass JD, Joshi HC. Non-toxic melanoma therapy by a novel tubulin-binding agent. International Journal of Cancer. Journal International Du Cancer. 126: 256-65. PMID 19626589 DOI: 10.1002/Ijc.24765 |
0.411 |
|
| 2010 |
Naik PK, Aneja R, Vangapandu S, Santoshi S, Joshi HC. Abstract 97:In silicocomputational modeling and virtual screening of novel noscapinoid library as potent microtubule interacting anticancer drugs Cancer Research. 70: 97-97. DOI: 10.1158/1538-7445.Am10-97 |
0.392 |
|
| 2010 |
Li S, Ghaleb AM, He J, Bughani U, Bialkowska AB, Yang VW, Joshi HC. Abstract 939: Chemoprevention of familial adenomatous polyposis by EM011 in theApcMin/+mouse model Cancer Research. 70: 939-939. DOI: 10.1158/1538-7445.Am10-939 |
0.366 |
|
| 2009 |
Bughani U, Li S, Joshi HC. Recent patents reveal microtubules as persistent promising target for novel drug development for cancers. Recent Patents On Anti-Infective Drug Discovery. 4: 164-82. PMID 19673697 DOI: 10.2174/157489109789318532 |
0.346 |
|
| 2009 |
Jaiswal AS, Aneja R, Connors SK, Joshi HC, Multani AS, Pathak S, Narayan S. 9-bromonoscapine-induced mitotic arrest of cigarette smoke condensate-transformed breast epithelial cells. Journal of Cellular Biochemistry. 106: 1146-56. PMID 19229861 DOI: 10.1002/Jcb.22099 |
0.384 |
|
| 2008 |
Liu M, Aneja R, Sun X, Xie S, Wang H, Wu X, Dong JT, Li M, Joshi HC, Zhou J. Parkin regulates Eg5 expression by Hsp70 ubiquitination-dependent inactivation of c-Jun NH2-terminal kinase. The Journal of Biological Chemistry. 283: 35783-8. PMID 18845538 DOI: 10.1074/Jbc.M806860200 |
0.319 |
|
| 2008 |
Aneja R, Liu M, Yates C, Gao J, Dong X, Zhou B, Vangapandu SN, Zhou J, Joshi HC. Multidrug resistance-associated protein-overexpressing teniposide-resistant human lymphomas undergo apoptosis by a tubulin-binding agent. Cancer Research. 68: 1495-503. PMID 18316614 DOI: 10.1158/0008-5472.Can-07-1874 |
0.377 |
|
| 2008 |
Aneja R, Vangapandu SN, Lopus M, Viswesarappa VG, Dhiman N, Verma A, Chandra R, Panda D, Joshi HC. Corrigendum to "Synthesis of microtubule-interfering halogenated noscapine analogs that perturb mitosis in cancer cells followed by cell death" [Biochem. Pharmacol. 72 (4) (2006) 415-426] (DOI:10.1016/j.bcp.2006.05.004) Biochemical Pharmacology. 75: 1439-1440. DOI: 10.1016/J.Bcp.2008.02.014 |
0.388 |
|
| 2007 |
Liu M, Li D, Aneja R, Joshi HC, Xie S, Zhang C, Zhou J. PO(2)-dependent differential regulation of multidrug resistance 1 gene expression by the c-Jun NH2-terminal kinase pathway. The Journal of Biological Chemistry. 282: 17581-6. PMID 17452336 DOI: 10.1074/Jbc.M702206200 |
0.309 |
|
| 2007 |
Aneja R, Ghaleb AM, Zhou J, Yang VW, Joshi HC. p53 and p21 determine the sensitivity of noscapine-induced apoptosis in colon cancer cells. Cancer Research. 67: 3862-70. PMID 17440101 DOI: 10.1158/0008-5472.Can-06-4282 |
0.34 |
|
| 2006 |
Aneja R, Vangapandu SN, Joshi HC. Synthesis and biological evaluation of a cyclic ether fluorinated noscapine analog. Bioorganic & Medicinal Chemistry. 14: 8352-8. PMID 17008104 DOI: 10.1016/J.Bmc.2006.09.012 |
0.353 |
|
| 2006 |
Aneja R, Zhou J, Zhou B, Chandra R, Joshi HC. Treatment of hormone-refractory breast cancer: apoptosis and regression of human tumors implanted in mice. Molecular Cancer Therapeutics. 5: 2366-77. PMID 16985071 DOI: 10.1158/1535-7163.Mct-06-0205 |
0.342 |
|
| 2006 |
Aneja R, Vangapandu SN, Lopus M, Viswesarappa VG, Dhiman N, Verma A, Chandra R, Panda D, Joshi HC. Synthesis of microtubule-interfering halogenated noscapine analogs that perturb mitosis in cancer cells followed by cell death. Biochemical Pharmacology. 72: 415-26. PMID 16780803 DOI: 10.1016/J.Bcp.2006.05.004 |
0.46 |
|
| 2006 |
Liu M, Aneja R, Liu C, Sun L, Gao J, Wang H, Dong JT, Sarli V, Giannis A, Joshi HC, Zhou J. Inhibition of the mitotic kinesin Eg5 up-regulates Hsp70 through the phosphatidylinositol 3-kinase/Akt pathway in multiple myeloma cells. The Journal of Biological Chemistry. 281: 18090-7. PMID 16627469 DOI: 10.1074/Jbc.M601324200 |
0.342 |
|
| 2006 |
Aneja R, Lopus M, Zhou J, Vangapandu SN, Ghaleb A, Yao J, Nettles JH, Zhou B, Gupta M, Panda D, Chandra R, Joshi HC. Rational design of the microtubule-targeting anti-breast cancer drug EM015. Cancer Research. 66: 3782-91. PMID 16585205 DOI: 10.1158/0008-5472.Can-05-2962 |
0.573 |
|
| 2006 |
Aneja R, Vangapandu SN, Lopus M, Chandra R, Panda D, Joshi HC. Development of a novel nitro-derivative of noscapine for the potential treatment of drug-resistant ovarian cancer and T-cell lymphoma. Molecular Pharmacology. 69: 1801-9. PMID 16517755 DOI: 10.1124/Mol.105.021899 |
0.423 |
|
| 2006 |
Zhou J, Liu M, Aneja R, Chandra R, Lage H, Joshi HC. Reversal of P-glycoprotein-mediated multidrug resistance in cancer cells by the c-Jun NH2-terminal kinase. Cancer Research. 66: 445-52. PMID 16397260 DOI: 10.1158/0008-5472.Can-05-1779 |
0.36 |
|
| 2006 |
Aneja R, Zhou J, Vangapandu SN, Zhou B, Chandra R, Joshi HC. Drug-resistant T-lymphoid tumors undergo apoptosis selectively in response to an antimicrotubule agent, EM011. Blood. 107: 2486-92. PMID 16282340 DOI: 10.1182/Blood-2005-08-3516 |
0.376 |
|
| 2005 |
Zhou J, Liu M, Luthra R, Jones J, Aneja R, Chandra R, Tekmal RR, Joshi HC. EM012, a microtubule-interfering agent, inhibits the progression of multidrug-resistant human ovarian cancer both in cultured cells and in athymic nude mice. Cancer Chemotherapy and Pharmacology. 55: 461-5. PMID 15690203 DOI: 10.1007/S00280-004-0903-1 |
0.377 |
|
| 2004 |
Zhou J, Liu M, Aneja R, Chandra R, Joshi HC. Enhancement of paclitaxel-induced microtubule stabilization, mitotic arrest, and apoptosis by the microtubule-targeting agent EM012. Biochemical Pharmacology. 68: 2435-41. PMID 15548390 DOI: 10.1016/J.Bcp.2004.08.032 |
0.432 |
|
| 2004 |
Landen JW, Hau V, Wang M, Davis T, Ciliax B, Wainer BH, Van Meir EG, Glass JD, Joshi HC, Archer DR. Noscapine crosses the blood-brain barrier and inhibits glioblastoma growth. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 5187-201. PMID 15297423 DOI: 10.1158/1078-0432.Ccr-04-0360 |
0.728 |
|
| 2004 |
Stillwell EE, Zhou J, Joshi HC. Human ninein is a centrosomal autoantigen recognized by CREST patient sera and plays a regulatory role in microtubule nucleation. Cell Cycle (Georgetown, Tex.). 3: 923-30. PMID 15190203 DOI: 10.4161/Cc.3.7.947 |
0.772 |
|
| 2004 |
Pozharskaya VP, Weakland LL, Zimring JC, Krug LT, Unger ER, Neisch A, Joshi H, Inoue N, Offermann MK. Short duration of elevated vIRF-1 expression during lytic replication of human herpesvirus 8 limits its ability to block antiviral responses induced by alpha interferon in BCBL-1 cells. Journal of Virology. 78: 6621-35. PMID 15163753 DOI: 10.1128/Jvi.78.12.6621-6635.2004 |
0.309 |
|
| 2003 |
Checchi PM, Nettles JH, Zhou J, Snyder JP, Joshi HC. Microtubule-interacting drugs for cancer treatment. Trends in Pharmacological Sciences. 24: 361-5. PMID 12871669 DOI: 10.1016/S0165-6147(03)00161-5 |
0.414 |
|
| 2003 |
Zhou J, Gupta K, Aggarwal S, Aneja R, Chandra R, Panda D, Joshi HC. Brominated derivatives of noscapine are potent microtubule-interfering agents that perturb mitosis and inhibit cell proliferation. Molecular Pharmacology. 63: 799-807. PMID 12644580 DOI: 10.1124/Mol.63.4.799 |
0.507 |
|
| 2002 |
Zhou J, Yao J, Joshi HC. Attachment and tension in the spindle assembly checkpoint. Journal of Cell Science. 115: 3547-55. PMID 12186941 DOI: 10.1242/Jcs.00029 |
0.598 |
|
| 2002 |
Zhou J, Gupta K, Yao J, Ye K, Panda D, Giannakakou P, Joshi HC. Paclitaxel-resistant human ovarian cancer cells undergo c-Jun NH2-terminal kinase-mediated apoptosis in response to noscapine. The Journal of Biological Chemistry. 277: 39777-85. PMID 12183452 DOI: 10.1074/Jbc.M203927200 |
0.571 |
|
| 2002 |
Landen JW, Lang R, McMahon SJ, Rusan NM, Yvon AM, Adams AW, Sorcinelli MD, Campbell R, Bonaccorsi P, Ansel JC, Archer DR, Wadsworth P, Armstrong CA, Joshi HC. Noscapine alters microtubule dynamics in living cells and inhibits the progression of melanoma. Cancer Research. 62: 4109-14. PMID 12124349 |
0.753 |
|
| 2002 |
Zhou J, Panda D, Landen JW, Wilson L, Joshi HC. Minor alteration of microtubule dynamics causes loss of tension across kinetochore pairs and activates the spindle checkpoint. The Journal of Biological Chemistry. 277: 17200-8. PMID 11864974 DOI: 10.1074/Jbc.M110369200 |
0.77 |
|
| 2002 |
Zhou J, Shu HB, Joshi HC. Regulation of tubulin synthesis and cell cycle progression in mammalian cells by gamma-tubulin-mediated microtubule nucleation. Journal of Cellular Biochemistry. 84: 472-83. PMID 11813253 DOI: 10.1002/Jcb.10033 |
0.67 |
|
| 2001 |
Ye K, Zhou J, Landen JW, Bradbury EM, Joshi HC. Sustained activation of p34(cdc2) is required for noscapine-induced apoptosis. The Journal of Biological Chemistry. 276: 46697-700. PMID 11679575 DOI: 10.1074/Jbc.C100550200 |
0.742 |
|
| 2001 |
Joshi HC, Zhou J. Gamma tubulin and microtubule nucleation in mammalian cells Methods in Cell Biology. 179-193. PMID 11550468 DOI: 10.1016/S0091-679X(01)67013-4 |
0.458 |
|
| 2001 |
Hendrickson TW, Yao J, Bhadury S, Corbett AH, Joshi HC. Conditional mutations in γ-tubulin reveal its involvement in chromosome segregation and cytokinesis Molecular Biology of the Cell. 12: 2469-2481. PMID 11514629 DOI: 10.1091/Mbc.12.8.2469 |
0.714 |
|
| 2000 |
Ke Y, Ye K, Grossniklaus HE, Archer DR, Joshi HC, Kapp JA. Noscapine inhibits tumor growth with little toxicity to normal tissues or inhibition of immune responses Cancer Immunology Immunotherapy. 49: 217-225. PMID 10941904 DOI: 10.1007/S002620000109 |
0.391 |
|
| 2000 |
Joshi HC, Zhou J. Noscapine and analogues as potential chemotherapeutic agents Drug News and Perspectives. 13: 543-546. DOI: 10.1358/dnp.2000.13.9.858482 |
0.337 |
|
| 1998 |
Manandhar G, Sutovsky P, Joshi HC, Stearns T, Schatten G. Centrosome reduction during mouse spermiogenesis. Developmental Biology. 203: 424-34. PMID 9808791 DOI: 10.1006/Dbio.1998.8947 |
0.441 |
|
| 1998 |
Kwon JH, Vogt Weisenhorn DM, Downen M, Ruan K, Roback L, Joshi H, Wainer BH. Beta-adrenergic and fibroblast growth factor receptors induce neuronal process outgrowth through different mechanisms. The European Journal of Neuroscience. 10: 2776-89. PMID 9758148 DOI: 10.1111/J.1460-9568.1998.00315.X |
0.357 |
|
| 1998 |
Joshi HC. Microtubule dynamics in living cells Current Opinion in Cell Biology. 10: 35-44. PMID 9484593 DOI: 10.1016/S0955-0674(98)80084-7 |
0.42 |
|
| 1998 |
Ye K, Ke Y, Keshava N, Shanks J, Kapp JA, Tekmal RR, Petros J, Joshi HC. Opium alkaloid noscapine is an antitumor agent that arrests metaphase and induces apoptosis in dividing cells Proceedings of the National Academy of Sciences of the United States of America. 95: 1601-1606. PMID 9465062 DOI: 10.1073/Pnas.95.4.1601 |
0.406 |
|
| 1996 |
Joshi HC, Palevitz BA. gamma-Tubulin and microtubule organization in plants. Trends in Cell Biology. 6: 41-4. PMID 15157488 DOI: 10.1016/0962-8924(96)81008-7 |
0.423 |
|
| 1996 |
Wolf KW, Joshi HC. Microtubule organization and distribution of gamma-tubulin in male meiosis of lepidoptera Molecular Reproduction and Development. 45: 547-559. PMID 8956293 DOI: 10.1002/(Sici)1098-2795(199612)45:4<547::Aid-Mrd17>3.0.Co;2-T |
0.437 |
|
| 1996 |
Wolf KW, Joshi HC. Distribution of gamma-tubulin differs in primary and secondary oocytes of Ephestia kuehniella (Pyralidae, Lepidoptera) Molecular Reproduction and Development. 45: 225-230. PMID 8914081 DOI: 10.1002/(Sici)1098-2795(199610)45:2<225::Aid-Mrd16>3.0.Co;2-# |
0.432 |
|
| 1996 |
Miller KE, Joshi HC. Tubulin transport in neurons. The Journal of Cell Biology. 133: 1355-66. PMID 8682870 DOI: 10.1083/Jcb.133.6.1355 |
0.373 |
|
| 1996 |
Joshi HC, Palevitz BA. γ-Tubulin and microtubule organization in plants Trends in Cell Biology. 6: 41-44. DOI: 10.1016/0962-8924(96)81008-7 |
0.314 |
|
| 1995 |
Wolf KW, Joshi HC. Microtubule organization and the distribution of γ-tubulin in spermatogenesis of a beetle, Tenebrio molitor (Tenebrionidae, Coleoptera, Insecta) Journal of Cell Science. 108: 3855-3865. PMID 8719891 |
0.358 |
|
| 1995 |
Shu HB, Li Z, Palacios MJ, Li Q, Joshi HC. A transient association of γ-tubulin at the midbody is required for the completion of cytokinesis during the mammalian cell division Journal of Cell Science. 108: 2955-2962. PMID 8537435 |
0.354 |
|
| 1995 |
Shu HB, Joshi HC. γ-Tubulin can both nucleate microtubule assembly and self-assemble into novel tubular structures in mammalian cells Journal of Cell Biology. 130: 1137-1147. PMID 7657698 DOI: 10.1083/Jcb.130.5.1137 |
0.451 |
|
| 1995 |
SORENG KM, WEBER DA, JOSHI H, MOORE JC, JENSEN PE. A Role for Microfilaments but Not Microtubules in Processing Soluble Antigens Cellular Immunology. 166: 25-34. PMID 7585978 DOI: 10.1006/Cimm.1995.0004 |
0.365 |
|
| 1995 |
Li Q, Joshi HC. γ-Tubulin is a minus end-specific microtubule binding protein Journal of Cell Biology. 131: 207-214. PMID 7559777 DOI: 10.1083/Jcb.131.1.207 |
0.507 |
|
| 1995 |
Liu B, Palevitz BA, Joshi HC. Experimental manipulation of γ‐tubulin distribution in arabidopsis using anti‐microtubule drugs Cell Motility and the Cytoskeleton. 31: 113-129. PMID 7553905 DOI: 10.1002/Cm.970310204 |
0.402 |
|
| 1995 |
Wolf KW, Mendoza AS, Mentzel M, Wossmann W, Joshi HC. Effects of cisplatin and mafosfamide on the interphase microtubular cytoskeleton of a human breast cancer cell line, MX-1, in vitro: A fine-structure and anti-tubulin immunofluorescence study International Journal of Oncology. 7: 593-602. |
0.306 |
|
| 1994 |
Joshi HC. Microtubule organizing centers and γ-tubulin Current Opinion in Cell Biology. 6: 55-62. PMID 8167026 DOI: 10.1016/0955-0674(94)90116-3 |
0.434 |
|
| 1994 |
Ahmad FJ, Joshi HC, Centonze VE, Baas PW. Inhibition of microtubule nucleation at the neuronal centrosome compromises axon growth. Neuron. 12: 271-80. PMID 8110458 DOI: 10.1016/0896-6273(94)90270-4 |
0.338 |
|
| 1994 |
Hoffman JC, Vaughn KC, Joshi HC. Structural and immunocytochemical characterization of microtubule organizing centers in pteridophyte spermatogenous cells Protoplasma. 179: 46-60. DOI: 10.1007/BF01360736 |
0.31 |
|
| 1994 |
Palevitz BA, Liu B, Joshi HC. γ-Tubulin in tobacco pollen tubes: association with generative cell and vegetative microtubules Sexual Plant Reproduction. 7: 209-214. DOI: 10.1007/Bf00232739 |
0.465 |
|
| 1993 |
Joshi HC, Baas PW. A new perspective on microtubules and axon growth. The Journal of Cell Biology. 121: 1191-6. PMID 8509443 DOI: 10.1083/Jcb.121.6.1191 |
0.308 |
|
| 1993 |
Palacios MJ, Joshi HC, Simerly C, Schatten G. γ-Tubulin reorganization during mouse fertilization and early development Journal of Cell Science. 104: 383-389. PMID 8505367 |
0.398 |
|
| 1993 |
Rizzolo LJ, Joshi HC. Apical orientation of the microtubule organizing center and associated γ-tubulin during the polarization of the retinal pigment epithelium in Vivo Developmental Biology. 157: 147-156. PMID 8482407 DOI: 10.1006/Dbio.1993.1119 |
0.429 |
|
| 1993 |
Joshi HC. γ‐Tubulin: The hub of cellular microtubule assemblies Bioessays. 15: 637-643. PMID 8274140 DOI: 10.1002/Bies.950151002 |
0.468 |
|
| 1993 |
Liu B, Marc J, Joshi HC, Palevitz BA. A γ-tubulin-related protein associated with the microtubule arrays of higher plants in a cell cycle-dependent manner Journal of Cell Science. 104: 1217-1228. PMID 7686171 |
0.344 |
|
| 1992 |
Joshi HC, Palacios MJ, McNamara L, Cleveland DW. γ-Tubulin is a centrosomal protein required for cell cycle-dependent microtubule nucleation Nature. 356: 80-83. PMID 1538786 DOI: 10.1038/356080A0 |
0.512 |
|
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