| Year |
Citation |
Score |
| 2024 |
Tewari M, Michalski S, Egan TM. Modulation of Microglial Function by ATP-Gated P2X7 Receptors: Studies in Rat, Mice and Human. Cells. 13. PMID 38247852 DOI: 10.3390/cells13020161 |
0.464 |
|
| 2022 |
Liang X, Janks L, Egan TM. Using Whole-Cell Electrophysiology and Patch-Clamp Photometry to Characterize P2X7 Receptor Currents. Methods in Molecular Biology (Clifton, N.J.). 2510: 217-237. PMID 35776327 DOI: 10.1007/978-1-0716-2384-8_11 |
0.414 |
|
| 2019 |
Liang X, Samways DSK, Cox J, Egan TM. Ca flux through splice variants of the ATP-gated ionotropic receptor P2X7 is regulated by its cytoplasmic N terminus. The Journal of Biological Chemistry. PMID 31248985 DOI: 10.1074/jbc.RA119.009666 |
0.42 |
|
| 2019 |
Janks L, Sprague RS, Egan TM. ATP-Gated P2X7 Receptors Require Chloride Channels To Promote Inflammation in Human Macrophages. Journal of Immunology (Baltimore, Md. : 1950). 202: 883-898. PMID 30598517 DOI: 10.4049/jimmunol.1801101 |
0.447 |
|
| 2018 |
Janks L, Sharma CVR, Egan TM. A central role for P2X7 receptors in human microglia. Journal of Neuroinflammation. 15: 325. PMID 30463629 DOI: 10.1186/s12974-018-1353-8 |
0.407 |
|
| 2017 |
Jin H, Han J, Resing D, Liu H, Yue X, Miller RL, Schoch KM, Miller TM, Perlmutter JS, Egan TM, Tu Z. Synthesis and in vitro characterization of a P2×7 radioligand [123I]TZ6019 and its response to neuroinflammatory in a mouse model of Alzheimer Disease. European Journal of Pharmacology. PMID 29225193 DOI: 10.1016/J.Ejphar.2017.12.006 |
0.346 |
|
| 2016 |
Migita K, Ozaki T, Shimoyama S, Yamada J, Nikaido Y, Furukawa T, Shiba Y, Egan TM, Ueno S. HSP90 regulation of P2X7 receptor function requires an intact cytoplasmic C-terminus. Molecular Pharmacology. PMID 27301716 DOI: 10.1124/mol.115.102988 |
0.52 |
|
| 2015 |
Liang X, Samways DS, Wolf K, Bowles EA, Richards JP, Bruno J, Dutertre S, DiPaolo RJ, Egan TM. Quantifying Ca2+ current and permeability in ATP-gated P2X7 receptors. The Journal of Biological Chemistry. 290: 7930-42. PMID 25645917 DOI: 10.1074/Jbc.M114.627810 |
0.409 |
|
| 2015 |
Liang X, Samways DS, Egan TM. Quantitative Measure of Ca2+ Current and Permeability in ATP-Gated P2X7 Receptors Biophysical Journal. 108: 288a-289a. DOI: 10.1016/j.bpj.2014.11.1575 |
0.448 |
|
| 2014 |
Xu J, Chai H, Ehinger K, Egan TM, Srinivasan R, Frick M, Khakh BS. Imaging P2X4 receptor subcellular distribution, trafficking, and regulation using P2X4-pHluorin. The Journal of General Physiology. 144: 81-104. PMID 24935743 DOI: 10.1085/Jgp.201411169 |
0.472 |
|
| 2014 |
Samways DS, Li Z, Egan TM. Principles and properties of ion flow in P2X receptors. Frontiers in Cellular Neuroscience. 8: 6. PMID 24550775 DOI: 10.3389/fncel.2014.00006 |
0.496 |
|
| 2013 |
Woods AS, Jackson SN, Lewis EK, Egan T, Muller L, Tabet JC, Schultz JA. MALDI/post ionization-ion mobility mass spectrometry of noncovalent complexes of dopamine receptors' epitopes. Journal of Proteome Research. 12: 1668-77. PMID 23469763 DOI: 10.1021/Pr301004W |
0.304 |
|
| 2012 |
Samways DS, Khakh BS, Egan TM. Allosteric modulation of Ca2+ flux in ligand-gated cation channel (P2X4) by actions on lateral portals. The Journal of Biological Chemistry. 287: 7594-602. PMID 22219189 DOI: 10.1074/Jbc.M111.322461 |
0.443 |
|
| 2011 |
Samways DS, Khakh BS, Dutertre S, Egan TM. Preferential use of unobstructed lateral portals as the access route to the pore of human ATP-gated ion channels (P2X receptors). Proceedings of the National Academy of Sciences of the United States of America. 108: 13800-5. PMID 21808018 DOI: 10.1073/Pnas.1017550108 |
0.4 |
|
| 2010 |
Goodnow RA, Hicks A, Sidduri A, Kowalczyk A, Dominique R, Qiao Q, Lou JP, Gillespie P, Fotouhi N, Tilley J, Cohen N, Choudhry S, Cavallo G, Tannu SA, Ventre JD, ... ... Egan T, et al. Discovery of novel and potent leukotriene B4 receptor antagonists. Part 1. Journal of Medicinal Chemistry. 53: 3502-16. PMID 20380377 DOI: 10.1021/Jm1001919 |
0.305 |
|
| 2010 |
Toulme E, Garcia A, Samways D, Egan TM, Carson MJ, Khakh BS. P2X4 receptors in activated C8-B4 cells of cerebellar microglial origin. The Journal of General Physiology. 135: 333-53. PMID 20231374 DOI: 10.1083/Jcb1892Oia7 |
0.326 |
|
| 2010 |
Migita K, Egan TM, Yamada J, Tomiyama M, Ueno S. The regulatory site of pore dilation and current facilitation in P2X7 receptor Neuroscience Research. 68: e110. DOI: 10.1016/j.neures.2010.07.2054 |
0.369 |
|
| 2010 |
Samways DS, Egan TM. Redox Modulation of ATP-Gated P2X7 Currents Biophysical Journal. 98: 702a. DOI: 10.1016/j.bpj.2009.12.3851 |
0.347 |
|
| 2010 |
Samways DS, Egan TM. Ca2+ Inhibition of Cation Conductance through TRPV1 Receptors Biophysical Journal. 98: 342a-343a. DOI: 10.1016/j.bpj.2009.12.1855 |
0.335 |
|
| 2010 |
Li Z, Harris S, Egan TM. P2X Receptors Encyclopedia of Neuroscience. 349-354. DOI: 10.1016/B978-008045046-9.01246-8 |
0.46 |
|
| 2009 |
Samways DS, Harkins AB, Egan TM. Native and recombinant ASIC1a receptors conduct negligible Ca2+ entry. Cell Calcium. 45: 319-25. PMID 19185346 DOI: 10.1016/j.ceca.2008.12.002 |
0.386 |
|
| 2008 |
Samways DS, Khakh BS, Egan TM. Tunable calcium current through TRPV1 receptor channels. The Journal of Biological Chemistry. 283: 31274-8. PMID 18775990 DOI: 10.1074/Jbc.C800131200 |
0.418 |
|
| 2008 |
Samways DS, Migita K, Li Z, Egan TM. On the role of the first transmembrane domain in cation permeability and flux of the ATP-gated P2X2 receptor. The Journal of Biological Chemistry. 283: 5110-7. PMID 18048351 DOI: 10.1074/jbc.M708713200 |
0.55 |
|
| 2007 |
Samways DS, Egan TM. Acidic amino acids impart enhanced Ca2+ permeability and flux in two members of the ATP-gated P2X receptor family. The Journal of General Physiology. 129: 245-56. PMID 17325195 DOI: 10.1085/jgp.200609677 |
0.476 |
|
| 2006 |
Egan TM, Samways DS, Li Z. Biophysics of P2X receptors. PflüGers Archiv : European Journal of Physiology. 452: 501-12. PMID 16708237 DOI: 10.1007/s00424-006-0078-1 |
0.49 |
|
| 2005 |
Khakh BS, Egan TM. Contribution of transmembrane regions to ATP-gated P2X2 channel permeability dynamics. The Journal of Biological Chemistry. 280: 6118-29. PMID 15556949 DOI: 10.1074/Jbc.M411324200 |
0.375 |
|
| 2004 |
Li Z, Migita K, Samways DS, Voigt MM, Egan TM. Gain and loss of channel function by alanine substitutions in the transmembrane segments of the rat ATP-gated P2X2 receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 7378-86. PMID 15317863 DOI: 10.1523/Jneurosci.1423-04.2004 |
0.493 |
|
| 2004 |
Egan TM, Cox JA, Voigt MM. Molecular structure of P2X receptors. Current Topics in Medicinal Chemistry. 4: 821-9. PMID 15078213 DOI: 10.2174/1568026043451005 |
0.503 |
|
| 2004 |
Egan TM, Khakh BS. Contribution of calcium ions to P2X channel responses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 3413-20. PMID 15056721 DOI: 10.1523/Jneurosci.5429-03.2004 |
0.385 |
|
| 2003 |
Kucenas S, Li Z, Cox JA, Egan TM, Voigt MM. Molecular characterization of the zebrafish P2X receptor subunit gene family. Neuroscience. 121: 935-45. PMID 14580944 DOI: 10.1016/S0306-4522(03)00566-9 |
0.414 |
|
| 2003 |
Egan TM, Migita K, Voigt MM. Relating the Structure of ATP-Gated Ion Channel Receptors to Their Function Current Topics in Membranes. 54: 183-202. DOI: 10.1016/S1063-5823(03)01006-8 |
0.516 |
|
| 2002 |
Diaz-Hernandez M, Cox JA, Migita K, Haines W, Egan TM, Voigt MM. Cloning and characterization of two novel zebrafish P2X receptor subunits. Biochemical and Biophysical Research Communications. 295: 849-53. PMID 12127972 DOI: 10.1016/S0006-291X(02)00760-X |
0.746 |
|
| 2001 |
Haines WR, Voigt MM, Migita K, Torres GE, Egan TM. On the contribution of the first transmembrane domain to whole-cell current through an ATP-gated ionotropic P2X receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 5885-92. PMID 11487611 DOI: 10.1523/Jneurosci.21-16-05885.2001 |
0.777 |
|
| 2001 |
Haines WR, Migita K, Cox JA, Egan TM, Voigt MM. The first transmembrane domain of the P2X receptor subunit participates in the agonist-induced gating of the channel. The Journal of Biological Chemistry. 276: 32793-8. PMID 11438537 DOI: 10.1074/Jbc.M104216200 |
0.763 |
|
| 2001 |
Migita K, Haines WR, Voigt MM, Egan TM. Polar residues of the second transmembrane domain influence cation permeability of the ATP-gated P2X(2) receptor. The Journal of Biological Chemistry. 276: 30934-41. PMID 11402044 DOI: 10.1074/Jbc.M103366200 |
0.743 |
|
| 2000 |
Egan TM, Cox JA, Voigt MM. Molecular cloning and functional characterization of the zebrafish ATP-gated ionotropic receptor P2X(3) subunit. Febs Letters. 475: 287-90. PMID 10869573 DOI: 10.1016/S0014-5793(00)01685-9 |
0.553 |
|
| 1999 |
Haines WR, Torres GE, Voigt MM, Egan TM. Properties of the novel ATP-gated ionotropic receptor composed of the P2X(1) and P2X(5) isoforms. Molecular Pharmacology. 56: 720-7. PMID 10496954 |
0.763 |
|
| 1999 |
Torres GE, Egan TM, Voigt MM. Identification of a domain involved in ATP-gated ionotropic receptor subunit assembly. The Journal of Biological Chemistry. 274: 22359-65. PMID 10428806 DOI: 10.1074/Jbc.274.32.22359 |
0.546 |
|
| 1999 |
Torres GE, Egan TM, Voigt MM. Hetero-oligomeric assembly of P2X receptor subunits. Specificities exist with regard to possible partners. The Journal of Biological Chemistry. 274: 6653-9. PMID 10037762 DOI: 10.1074/Jbc.274.10.6653 |
0.523 |
|
| 1998 |
Torres GE, Haines WR, Egan TM, Voigt MM. Co-expression of P2X1 and P2X5 receptor subunits reveals a novel ATP-gated ion channel. Molecular Pharmacology. 54: 989-93. PMID 9855626 DOI: 10.1124/Mol.54.6.989 |
0.757 |
|
| 1998 |
McCullough LA, Egan TM, Westfall TC. Neuropeptide Y receptors involved in calcium channel regulation in PC12 cells. Regulatory Peptides. 75: 101-7. PMID 9802399 DOI: 10.1016/S0167-0115(98)00058-5 |
0.408 |
|
| 1998 |
Torres GE, Egan TM, Voigt MM. N-Linked glycosylation is essential for the functional expression of the recombinant P2X2 receptor. Biochemistry. 37: 14845-51. PMID 9778359 DOI: 10.1021/Bi981209G |
0.498 |
|
| 1998 |
Torres GE, Egan TM, Voigt MM. Topological analysis of the ATP-gated ionotropic [correction of ionotrophic] P2X2 receptor subunit. Febs Letters. 425: 19-23. PMID 9540999 DOI: 10.1016/S0014-5793(98)00179-3 |
0.533 |
|
| 1998 |
Egan TM, Haines WR, Voigt MM. A domain contributing to the ion channel of ATP-gated P2X2 receptors identified by the substituted cysteine accessibility method. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 2350-9. PMID 9502796 DOI: 10.1523/Jneurosci.18-07-02350.1998 |
0.755 |
|
| 1998 |
Torres GE, Egan TM, Voigt MM. Erratum to: Topological analysis of the ATP-gated ionotropic P2X2
receptor subunit (FEBS 19946) Febs Letters. 427: 152-152. DOI: 10.1016/S0014-5793(98)00332-9 |
0.569 |
|
| 1993 |
Egan TM, Dagan D, Levitan IB. Properties and modulation of a calcium-activated potassium channel in rat olfactory bulb neurons. Journal of Neurophysiology. 69: 1433-42. PMID 8389824 DOI: 10.1152/jn.1993.69.5.1433 |
0.363 |
|
| 1992 |
Egan TM, Dagan D, Kupper J, Levitan IB. Na(+)-activated K+ channels are widely distributed in rat CNS and in Xenopus oocytes. Brain Research. 584: 319-21. PMID 1515948 DOI: 10.1016/0006-8993(92)90913-T |
0.305 |
|
| 1989 |
Egan TM. Single cell studies of the actions of agonists and antagonists on nicotinic receptors of the central nervous system Progress in Brain Research. 79: 73-83. PMID 2573913 DOI: 10.1016/S0079-6123(08)62466-8 |
0.35 |
|
| 1981 |
Egan T, North R. Both mu and delta opiate receptors exist on the same neuron Science. 214: 923-924. PMID 6272393 DOI: 10.1126/Science.6272393 |
0.455 |
|
| Show low-probability matches. |