| Year |
Citation |
Score |
| 2021 |
Xu K, Shi X, Husted C, Hong R, Wang Y, Ning B, Sullivan T, Rieger-Christ K, Duan F, Marques H, Gower A, Xiao X, Liu H, Liu G, Duclos G, ... Spira A, et al. Smoking Modulates Different Secretory Subpopulations Expressing SARS-CoV-2 Entry Genes in the Nasal and Bronchial Airways. Research Square. PMID 34729557 DOI: 10.21203/rs.3.rs-887718/v1 |
0.701 |
|
| 2021 |
Maoz A, Merenstein C, Koga Y, Potter A, Gower AC, Liu G, Zhang S, Liu H, Stevenson C, Spira A, Reid ME, Campbell JD, Mazzilli SA, Lenburg ME, Beane J. Elevated T cell repertoire diversity is associated with progression of lung squamous cell premalignant lesions. Journal For Immunotherapy of Cancer. 9. PMID 34580161 DOI: 10.1136/jitc-2021-002647 |
0.655 |
|
| 2021 |
Becker EJ, Faiz A, van den Berge M, Timens W, Hiemstra PS, Clark K, Liu G, Xiao X, Alekseyev YO, O'Connor G, Lam S, Spira A, Lenburg ME, Steiling K. Bronchial gene expression signature associated with rate of subsequent FEV decline in individuals with and at risk of COPD. Thorax. PMID 33972452 DOI: 10.1136/thoraxjnl-2019-214476 |
0.371 |
|
| 2021 |
Tilston-Lunel A, Mazzilli S, Kingston NM, Szymaniak AD, Hicks-Berthet J, Kern JG, Abo K, Reid ME, Perdomo C, Wilson AA, Spira A, Beane J, Varelas X. Aberrant epithelial polarity cues drive the development of precancerous airway lesions. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33903236 DOI: 10.1073/pnas.2019282118 |
0.685 |
|
| 2021 |
Han G, Sinjab A, Hara K, Treekitkarnmongkol W, Brennan P, Chang K, Bogatenkova E, Sanchez-Espiridion B, Behrens C, Solis LM, Gao B, Girard L, Zhang J, Sepesi B, Cascone T, ... ... Spira AE, et al. Single-Cell Expression Landscape of SARS-CoV-2 Receptor and Host Proteases in Normal and Malignant Lung Tissues from Pulmonary Adenocarcinoma Patients. Cancers. 13. PMID 33809063 DOI: 10.3390/cancers13061250 |
0.457 |
|
| 2021 |
Mazzone PJ, Lamb C, Rieger-Christ KM, Reddy CB, Qu J, Wu S, Ding J, Whitney D, Pankratz DG, Babiarz J, Lofaro L, Walsh PS, Wilde J, Bhorade SM, Huang J, ... ... Spira A, et al. Early candidate nasal swab classifiers developed using machine learning and whole transcriptome sequencing may improve early lung cancer detection. Journal of Clinical Oncology. 39: 8551-8551. DOI: 10.1200/JCO.2021.39.15_SUPPL.8551 |
0.379 |
|
| 2021 |
Burks EJ, Zhang J, Sullivan TB, Shi X, Sands JM, Regis SM, McKee BJ, McKee AB, Zhang S, Liu H, Liu G, Spira A, Beane J, Lenburg ME, Rieger-Christ KM. Pathologic and gene expression comparison of CT- screen detected and routinely detected stage I/0 lung adenocarcinoma in NCCN risk-matched cohorts. Cancer Treatment and Research Communications. 29: 100486. DOI: 10.1016/j.ctarc.2021.100486 |
0.302 |
|
| 2020 |
Ostrin EJ, Sidransky D, Spira A, Hanash SM. Biomarkers for lung cancer screening and detection. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 33093160 DOI: 10.1158/1055-9965.EPI-20-0865 |
0.364 |
|
| 2020 |
Faiz A, Imkamp K, van der Wiel E, Boudewijn IM, Koppelman GH, Brandsma CA, Kerstjens HAM, Timens W, Vroegop S, Pasma HR, Boersma WG, Wielders P, van den Elshout F, Mansour K, Steiling K, ... Spira A, et al. Identifying a nasal gene expression signature associated with hyperinflation and treatment response in severe COPD. Scientific Reports. 10: 17415. PMID 33060632 DOI: 10.1038/s41598-020-72551-0 |
0.308 |
|
| 2020 |
Billatos E, Ash SY, Duan F, Xu K, Romanoff J, Marques H, Moses E, Han MK, Regan EA, Bowler RP, Mason SE, Doyle TJ, San José Estépar R, Rosas IO, Ross JC, ... ... Spira A, et al. Distinguishing smoking related lung disease phenotypes via imaging and molecular features. Chest. PMID 32946850 DOI: 10.1016/J.Chest.2020.08.2115 |
0.378 |
|
| 2020 |
Treekitkarnmongkol W, Hassane M, Sinjab A, Chang K, Hara K, Rahal Z, Zhang J, Lu W, Sivakumar S, McDowell TL, Kantrowitz J, Zhou J, Lang W, Xu L, Ochieng JK, ... ... Spira AE, et al. Augmented Lipocalin-2 is Associated with COPD and Counteracts Lung Adenocarcinoma Development. American Journal of Respiratory and Critical Care Medicine. PMID 32730093 DOI: 10.1164/Rccm.202004-1079Oc |
0.416 |
|
| 2020 |
Shi X, Zhang J, Callori S, Campbell J, Fine D, Gesthalter Y, Liu G, Xiao X, Spira A, Lenburg M, Beane J. Abstract 3377: NSCLC subtype-associated molecular and cellular alterations in the normal-appearing bronchial epithelium Cancer Research. 80: 3377-3377. DOI: 10.1158/1538-7445.Am2020-3377 |
0.756 |
|
| 2020 |
Sinjab A, Han G, Treekitkarnmongkol W, Brennan P, Hara K, Chang K, Bogatenkova E, Sanchez-Espiridion B, Behrens C, Zhang J, Sepesi B, Cascone T, Gibbons DL, Chen J, Eapen G, ... ... Spira AE, et al. Abstract 1518: A single-cell transcriptomic atlas of lung adenocarcinoma and adjacent normal-appearing tissue Tumor Biology. DOI: 10.1158/1538-7445.Am2020-1518 |
0.338 |
|
| 2020 |
Merenstein C, Breda J, Mazzilli S, Burks E, Stevenson C, Reid M, Spira A, Lenburg M, Beane J. Abstract 1098: Mediators of early immune response in bronchial premalignant lesions Tumor Biology. DOI: 10.1158/1538-7445.Am2020-1098 |
0.578 |
|
| 2019 |
Duclos GE, Teixeira VH, Autissier P, Gesthalter YB, Reinders-Luinge MA, Terrano R, Dumas YM, Liu G, Mazzilli SA, Brandsma CA, van den Berge M, Janes SM, Timens W, Lenburg ME, Spira A, et al. Characterizing smoking-induced transcriptional heterogeneity in the human bronchial epithelium at single-cell resolution. Science Advances. 5: eaaw3413. PMID 31844660 DOI: 10.1126/Sciadv.Aaw3413 |
0.671 |
|
| 2019 |
Garland L, Guillen-Rodriguez J, Hsu CH, Yozwiak M, Zhang HH, Alberts DS, Davis LE, Szabo E, Merenstein C, Lel J, Zhang X, Liu H, Liu G, Spira AE, Beane J, et al. Effect of intermittent versus continuous low dose aspirin on nasal epithelium gene expression in current smokers: A randomized, double-blinded trial. Cancer Prevention Research (Philadelphia, Pa.). PMID 31451521 DOI: 10.1158/1940-6207.Capr-19-0036 |
0.695 |
|
| 2019 |
Corbett SE, Nitzberg M, Moses E, Kleerup E, Wang T, Perdomo C, Perdomo C, Liu G, Zhang S, Liu H, Elashoff DA, Brooks DR, O'Connor GT, Dubinett SM, Spira A, et al. Gene Expression Alterations in the Bronchial Epithelium of Electronic Cigarette Users. Chest. PMID 31233743 DOI: 10.1016/J.Chest.2019.05.022 |
0.346 |
|
| 2019 |
Krysan K, Tran LM, Grimes BS, Fishbein GA, Seki A, Gardner BK, Walser TC, Salehi-Rad R, Yanagawa J, Lee JM, Sharma S, Aberle D, Spira AE, Elashoff DA, Wallace WD, et al. The immune contexture associates with the genomic landscape in lung adenomatous premalignancy. Cancer Research. PMID 31142513 DOI: 10.1158/0008-5472.Can-19-0153 |
0.351 |
|
| 2019 |
Hijazi K, Malyszko B, Steiling K, Xiao X, Liu G, Alekseyev YO, Dumas YM, Hertsgaard L, Jensen J, Hatsukami D, Brooks DR, O'Connor G, Beane J, Lenburg ME, Spira A. Tobacco-Related Alterations in Airway Gene Expression are Rapidly Reversed Within Weeks Following Smoking-Cessation. Scientific Reports. 9: 6978. PMID 31061400 DOI: 10.1038/S41598-019-43295-3 |
0.664 |
|
| 2019 |
Beane JE, Mazzilli SA, Campbell JD, Duclos G, Krysan K, Moy C, Perdomo C, Schaffer M, Liu G, Zhang S, Liu H, Vick J, Dhillon SS, Platero SJ, Dubinett SM, ... ... Spira AE, et al. Molecular subtyping reveals immune alterations associated with progression of bronchial premalignant lesions. Nature Communications. 10: 1856. PMID 31015447 DOI: 10.1038/S41467-019-09834-2 |
0.707 |
|
| 2019 |
Kadara H, Sivakumar S, Jakubek Y, San Lucas FA, Lang W, McDowell T, Weber Z, Behrens C, Davies GE, Kalhor N, Moran C, El-Zein R, Mehran R, Swisher SG, Wang J, ... ... Spira AE, et al. Driver Mutations in Normal Airway Epithelium Elucidate Spatiotemporal Resolution of Lung Cancer. American Journal of Respiratory and Critical Care Medicine. PMID 30896962 DOI: 10.1164/Rccm.201806-1178Oc |
0.333 |
|
| 2019 |
Billatos E, Duan F, Moses E, Marques H, Mahon I, Dymond L, Apgar C, Aberle D, Washko G, Spira A. Detection of early lung cancer among military personnel (DECAMP) consortium: study protocols. Bmc Pulmonary Medicine. 19: 59. PMID 30845938 DOI: 10.1186/S12890-019-0825-7 |
0.352 |
|
| 2019 |
Teixeira VH, Pipinikas CP, Pennycuick A, Lee-Six H, Chandrasekharan D, Beane J, Morris TJ, Karpathakis A, Feber A, Breeze CE, Ntolios P, Hynds RE, Falzon M, Capitanio A, Carroll B, ... ... Spira A, et al. Deciphering the genomic, epigenomic, and transcriptomic landscapes of pre-invasive lung cancer lesions. Nature Medicine. PMID 30664780 DOI: 10.1038/S41591-018-0323-0 |
0.7 |
|
| 2019 |
xu f, Tanabe N, Macdonough J, Vasilescu D, Ikezoe K, Kinose D, Ng K, Verleden S, Vanaudenaerde B, Verschakelen J, Cooper J, Lenburg M, Spira A, Ng R, Hogg J. The transition from normal lung anatomy to Fibrosis in IPF European Respiratory Journal. DOI: 10.1183/13993003.Congress-2019.Oa470 |
0.3 |
|
| 2019 |
Becker EJ, Faiz A, Berge MVd, Timens W, Hiemstra PS, Liu G, Zhang X, Alekseyev YO, O'Connor GT, Lam S, Spira A, Lenburg ME, Steiling K. A Bronchial Airway Gene Expression Signature of Future Lung Function Decline Is Enriched in XBP1-Regulated Genes American Journal of Respiratory and Critical Care Medicine. 199. DOI: 10.1164/Ajrccm-Conference.2019.199.1_Meetingabstracts.A7234 |
0.409 |
|
| 2019 |
Mazzilli SA, Hijazi K, Pihl R, Belkina A, Zhang X, Liu G, Lenburg M, Stevenson C, Spira A, Beane J. Abstract 660: The molecular characterization of a murine lung premalignancy model for lung cancer interception Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-660 |
0.698 |
|
| 2019 |
Zhang J, Burks E, Beane J, Sullivan T, Liu G, Dubinett S, Lenburg M, Spira A. Abstract 3530: Gene expression alterations associated with histologic aggressiveness in stage I lung adenocarcinomas Cancer Research. 79: 3530-3530. DOI: 10.1158/1538-7445.Sabcs18-3530 |
0.686 |
|
| 2019 |
Hijazi K, Lel J, Billatos E, Moses E, Stevenson CS, Lorenzi MV, Liu G, Campbell JD, Koga Y, Zhang J, Duan F, Marques H, Lenburg ME, Spira AE, Beane J. Abstract 3393: Altered immune response in the transcriptome of patients with lung cancer Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-3393 |
0.676 |
|
| 2019 |
Lamb C, Hospital L, Center M, Ding J, Saberi S, Pankratz D, Babiarz J, Chamberlin J, Bhorade S, Wilde J, Walsh P, Lofaro L, Huang J, Stevenson C, Lenburg M, ... ... Spira A, et al. LUNG CANCER DETECTION VIA WHOLE-TRANSCRIPTOME RNA SEQUENCING OF NASAL EPITHELIUM Chest. 156: A1091-A1092. DOI: 10.1016/J.Chest.2019.08.1005 |
0.366 |
|
| 2018 |
Seijo LM, Peled N, Ajona D, Boeri M, Field JK, Sozzi G, Pio R, Zulueta JJ, Spira A, Massion PP, Mazzone PJ, Montuenga LM. Biomarkers in Lung Cancer Screening: Achievements, Promises, and Challenges. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. PMID 30529598 DOI: 10.1016/J.Jtho.2018.11.023 |
0.327 |
|
| 2018 |
Khalil A, Dekmak B, Boulos F, Kantrowitz J, Spira A, Fujimoto J, Kadara H, El-Hachem N, Nemer G. Transcriptomic Alterations in Lung Adenocarcinoma Unveil New Mechanisms Targeted by the Subfamily of Tumor Suppressor Genes. Frontiers in Oncology. 8: 482. PMID 30425966 DOI: 10.3389/Fonc.2018.00482 |
0.445 |
|
| 2018 |
Billatos E, Faiz A, Gesthalter YO, LeClerc A, Alekseyev Y, Zhang X, Liu G, Ten Hacken NHT, Heijink I, Timens W, Brandsma CA, Postma DS, van den Berge M, Spira A, Lenburg ME. The Impact of Acute Exposure to Cigarette Smoke on Airway Gene Expression. Physiological Genomics. PMID 29932825 DOI: 10.1152/Physiolgenomics.00092.2017 |
0.301 |
|
| 2018 |
Billatos E, Vick JL, Lenburg ME, Spira AE. The Airway Transcriptome as a Biomarker for Early Lung Cancer Detection. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29463557 DOI: 10.1158/1078-0432.Ccr-16-3187 |
0.48 |
|
| 2018 |
Kantrowitz J, Sinjab A, Xu L, McDowell TL, Sivakumar S, Lang W, Nunomura-Nakamura S, Fukuoka J, Nemer G, Darwiche N, Chami H, Tfayli A, Wistuba II, Scheet P, Fujimoto J, ... Spira AE, et al. Genome-wide gene expression changes in the normal-appearing airway during the evolution of smoking-associated lung adenocarcinoma. Cancer Prevention Research (Philadelphia, Pa.). PMID 29382653 DOI: 10.1158/1940-6207.Capr-17-0295 |
0.518 |
|
| 2018 |
Faiz A, Billatos E, Lenburg M, Spira A, Vonk J, Boezen M, Heijink I, Berge MVD. SNPs which influence the transcriptional response to acute smoke exposure are associated with long term lung function decline in smokers European Respiratory Journal. 52. DOI: 10.1183/13993003.Congress-2018.Pa927 |
0.307 |
|
| 2018 |
Steiling K, Zhang J, Sands J, Sullivan T, Billatos E, Moses E, Liu G, Lamb C, McKee B, Lenburg M, Spira A, Rieger-Christ K. Abstract A15: Nasal gene expression for the diagnostic evaluation of indeterminate pulmonary nodules within a screening population Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Aacriaslc18-A15 |
0.483 |
|
| 2018 |
Beane JE, Mazzilli S, Tassinari A, Campbell J, Moy C, Schaffer M, Perdomo C, Jenkins D, Pine MB, Liu G, Zhang S, Lin H, Vick J, Johnson E, Platero S, ... ... Spira A, et al. Abstract A05: Bronchial premalignant lesions have distinct molecular subtypes associated with future histologic progression Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Aacriaslc18-A05 |
0.739 |
|
| 2018 |
Mazzilli S, Zhang S, Liu G, Lenburg M, Spira A, Beane J. Abstract B18: The carcinogen-induced NTCU model: A preclinical mouse model for lung cancer interception Cancer Research. 78. DOI: 10.1158/1538-7445.Mousemodels17-B18 |
0.723 |
|
| 2018 |
Sivakumar S, Jakubek Y, Lucas FAS, Lang W, McDowell C, Weber Z, Behrens C, Kalhor N, Moran C, El-Zein R, Davies G, Fujimoto J, Mehran R, Swisher SG, Wang J, ... ... Spira AE, et al. Abstract 3997: Somatic mutational processes in the cancerization field of the normal-appearing airway reveal early drivers in the development of non-small cell lung cancer Tumor Biology. DOI: 10.1158/1538-7445.Am2018-3997 |
0.363 |
|
| 2018 |
Shi X, Duclos G, Campbell J, Gesthalter Y, Autissier P, Dumas YM, Terrano R, Liu G, Lenburg ME, Spira A, Beane J. Abstract 2534: Single-cell RNA sequencing reveals lung cancer-associated alterations in bronchial cell subpopulations in the mainstem bronchus Cancer Research. 78: 2534-2534. DOI: 10.1158/1538-7445.Am2018-2534 |
0.743 |
|
| 2018 |
Shi X, Billatos E, Zhang J, Beane J, Moses E, Liu G, Stevenson C, Lenburg ME, Spira A. Abstract 2531: Diagnostic evaluation of indeterminate pulmonary nodules via rna-seq of bronchial epithelium Cancer Research. 78: 2531-2531. DOI: 10.1158/1538-7445.Am2018-2531 |
0.727 |
|
| 2018 |
LEE H, BHADRA K, WHITTEN P, ESTERLE M, BERNSTEIN M, DOTSON T, BENZAQUEN S, MAZZONE P, GORDON J, HOGARTH D, JOHNSON M, HUANG J, GRISCOM B, LOFARO L, KENNEDY G, ... SPIRA A, et al. CLINICAL UTILITY OF A BRONCHIAL GENOMIC CLASSIFIER FOR LUNG CANCER DETECTION: RESULTS FROM A MULTICENTER PROSPECTIVE REGISTRY Chest. 154: 597A-599A. DOI: 10.1016/J.Chest.2018.08.540 |
0.358 |
|
| 2017 |
Boudewijn IM, Faiz A, Steiling K, van der Wiel E, Telenga ED, Hoonhorst SJM, Ten Hacken NHT, Brandsma CA, Kerstjens HAM, Timens W, Heijink IH, Jonker MR, de Bruin HG, Sebastiaan Vroegop J, Pasma HR, ... ... Spira A, et al. Nasal gene expression differentiates COPD from controls and overlaps bronchial gene expression. Respiratory Research. 18: 213. PMID 29268739 DOI: 10.1186/S12931-017-0696-5 |
0.306 |
|
| 2017 |
Dubinett SM, Spira AE. Impact of COPD on Immune-based Treatment for Lung Cancer: Moving Towards Disease Interception. American Journal of Respiratory and Critical Care Medicine. PMID 29072842 DOI: 10.1164/Rccm.201710-2065Ed |
0.354 |
|
| 2017 |
Khalil AA, Sivakumar S, Lucas FAS, McDowell T, Lang W, Tabata K, Fujimoto J, Yatabe Y, Spira A, Scheet P, Nemer G, Kadara H. TBX2 subfamily suppression in lung cancer pathogenesis: a high-potential marker for early detection. Oncotarget. 8: 68230-68241. PMID 28978111 DOI: 10.18632/Oncotarget.19938 |
0.457 |
|
| 2017 |
Tessema M, Yingling CM, Picchi MA, Wu G, Ryba T, Lin Y, Bungum AO, Edell ES, Spira A, Belinsky SA. ANK1 Methylation Regulates Expression of MicroRNA-486-5p and Discriminates Lung tumors by Histology and Smoking Status. Cancer Letters. PMID 28965852 DOI: 10.1016/J.Canlet.2017.09.038 |
0.337 |
|
| 2017 |
Sivakumar S, San Lucas FA, McDowell TL, Lang W, Xu L, Fujimoto J, Zhang J, Futreal PA, Fukuoka J, Yatabe Y, Dubinett SM, Spira AE, Fowler J, Hawk ET, Wistuba II, et al. Genomic landscape of atypical adenomatous hyperplasia reveals divergent modes to lung adenocarcinoma. Cancer Research. PMID 28951454 DOI: 10.1158/0008-5472.Can-17-1605 |
0.362 |
|
| 2017 |
Pavel AB, Campbell JD, Liu G, Elashoff DA, Dubinett SM, Smith K, Whitney D, Lenburg ME, Spira AE. Alterations in bronchial airway microRNA expression for lung cancer detection. Cancer Prevention Research (Philadelphia, Pa.). PMID 28877936 DOI: 10.1158/1940-6207.Capr-17-0098 |
0.44 |
|
| 2017 |
Suzuki M, Sze MA, Campbell JD, Brothers JF, Lenburg ME, McDonough JE, Elliott WM, Cooper JD, Spira A, Hogg JC. The cellular and molecular determinants of emphysematous destruction in COPD. Scientific Reports. 7: 9562. PMID 28842670 DOI: 10.1038/S41598-017-10126-2 |
0.357 |
|
| 2017 |
Beane J, Campbell JD, Lel J, Vick J, Spira A. Genomic approaches to accelerate cancer interception. The Lancet. Oncology. 18: e494-e502. PMID 28759388 DOI: 10.1016/S1470-2045(17)30373-X |
0.62 |
|
| 2017 |
Beane J, Mazzilli SA, Tassinari AM, Liu G, Zhang X, Liu H, Dy Buncio A, Dhillon SS, Platero SJ, Lenburg ME, Reid ME, Lam S, Spira AE. Detecting the Presence and Progression of Premalignant Lung Lesions via Airway Gene Expression. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28533227 DOI: 10.1158/1078-0432.Ccr-16-2540 |
0.743 |
|
| 2017 |
Vachani A, Sequist LV, Spira A. AJRCCM: 100-Year Anniversary. The Shifting Landscape for Lung Cancer: Past, Present, and Future. American Journal of Respiratory and Critical Care Medicine. 195: 1150-1160. PMID 28459327 DOI: 10.1164/Rccm.201702-0433Ci |
0.384 |
|
| 2017 |
Obeidat M, Nie Y, Fishbane N, Li X, Bossé Y, Joubert P, Nickle DC, Hao K, Postma DS, Timens W, Sze MA, Shannon CP, Hollander Z, Ng RT, McManus B, ... ... Spira A, et al. Integrative Genomics of Emphysema Associated Genes Reveals Potential Disease Biomarkers. American Journal of Respiratory Cell and Molecular Biology. PMID 28459279 DOI: 10.1165/Rcmb.2016-0284Oc |
0.379 |
|
| 2017 |
Boudewijn IM, Faiz A, Steiling K, Wiel Evd, Telenga E, Hoonhorst S, Hacken Nt, Brandsma C, Kerstjens H, Timens W, Heijink I, Jonker M, Bruin Hd, Vroegop S, Pasma H, ... ... Spira A, et al. A nasal gene expression profile differentiates individuals with and without COPD and overlaps bronchial gene expression European Respiratory Journal. 50. DOI: 10.1183/1393003.Congress-2017.Pa4470 |
0.323 |
|
| 2017 |
Beane JE, Mazzilli S, Campbell J, Moy C, Schaffer M, Perdomo C, Jenkins D, Liu G, Zhang S, Liu H, Vick J, Johnson E, Platero S, Lenburg M, Reid M, ... ... Spira A, et al. Abstract 5002: Premalignant squamous cell lung carcinoma lesions have distinct molecular subtypes associated with histologic progression Cancer Research. 77: 5002-5002. DOI: 10.1158/1538-7445.Am2017-5002 |
0.671 |
|
| 2017 |
Campbell J, Zhang X, Dhillon SS, Perdomo C, Mazzilli S, Geshalter Y, Liu G, Zhang S, Lin H, Vick J, Moy C, Monti S, Johnson E, Meyerson M, Dubinett S, ... ... Spira A, et al. Abstract 3259: The genomic landscape of premalignant lung squamous cell carcinoma lesions Cancer Research. 77: 3259-3259. DOI: 10.1158/1538-7445.Am2017-3259 |
0.663 |
|
| 2017 |
Sivakumar S, Jakubek Y, Lang W, McDowell T, Garcia MM, Chow C, Weber Z, Behrens C, Kalhor N, Moran C, El-Zein R, Davies G, Fujimoto J, Mehran R, Swisher SG, ... ... Spira AE, et al. Abstract 1434: Mutational landscape in the normal-appearing airway cancerization field of early-stage non-small cell lung cancer Cancer Research. 77: 1434-1434. DOI: 10.1158/1538-7445.Am2017-1434 |
0.36 |
|
| 2017 |
Duclos GE, Campbell JD, Gesthalter Y, Autissier P, Dumas YM, Terrano R, Liu G, Lenburg ME, Spira A, Beane J. Abstract 1433: Single cell RNA sequencing reveals smoking-associated alterations in bronchial airway epithelial subpopulations Cancer Research. 77: 1433-1433. DOI: 10.1158/1538-7445.Am2017-1433 |
0.746 |
|
| 2017 |
Mazzilli SA, Tassinari A, Xiao X, Liu G, Dhillon S, Johnson C, Reid M, Lenburg M, Spira A, Beane J. Abstract 1252: A pre-clinical model for lung cancer interception: gene expression similarities between human and mouse bronchial premalignant lesions Cancer Research. 77: 1252-1252. DOI: 10.1158/1538-7445.Am2017-1252 |
0.715 |
|
| 2017 |
Sivakumar S, San Lucas F, McDowell T, Lang W, Xu L, Fujimoto J, Zhang J, Wistuba I, Futreal F, Fukuoka J, Yatabe Y, Dubinett S, Spira A, Fowler J, Hawk E, et al. Genomic Landscape of Atypical Adenomatous Hyperplasia and Their Progression to Lung Adenocarcinomas Journal of Thoracic Oncology. 12: S1546. DOI: 10.1016/J.Jtho.2017.06.061 |
0.341 |
|
| 2017 |
Lee H, Whitten P, Bhadra K, Dotson T, Hogarth D, Benzaquen S, Pritchett M, Gordon J, Bedekar A, Esterle M, Smith K, Bianchi P, Lenburg M, Spira A. Prospective Utility of a Bronchial Genomic Classifier for Lung Cancer Detection: Interim Results From a Multicenter Prospective Registry Chest. 152: A625. DOI: 10.1016/J.Chest.2017.08.658 |
0.369 |
|
| 2016 |
Rahman SM, Ji X, Zimmerman LJ, Li M, Harris BK, Hoeksema MD, Trenary IA, Zou Y, Qian J, Slebos RJ, Beane J, Spira A, Shyr Y, Eisenberg R, Liebler DC, et al. The airway epithelium undergoes metabolic reprogramming in individuals at high risk for lung cancer. Jci Insight. 1: e88814. PMID 27882349 DOI: 10.1172/Jci.Insight.88814 |
0.678 |
|
| 2016 |
Moses E, Wang T, Corbett S, Jackson GR, Drizik E, Perdomo C, Perdomo C, Kleerup E, Brooks D, O'Connor G, Dubinett S, Hayden P, Lenburg ME, Spira A. Molecular impact of electronic cigarette aerosol exposure in human bronchial epithelium. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 27701119 DOI: 10.1093/Toxsci/Kfw198 |
0.309 |
|
| 2016 |
Lam S, Mandrekar SJ, Gesthalter Y, Allen Ziegler KL, Seisler DK, Midthun DE, Mao JT, Aubry MC, McWilliams A, Sin DD, Shaipanich T, Liu G, Johnson E, Bild AH, Lenburg ME, ... ... Spira AE, et al. A Randomized Phase IIb Trial of myo-Inositol in Smokers with Bronchial Dysplasia. Cancer Prevention Research (Philadelphia, Pa.). PMID 27658890 DOI: 10.1158/1940-6207.Capr-15-0254 |
0.624 |
|
| 2016 |
Spira A, Halmos B, Powell CA. Update in Lung Cancer 2015. American Journal of Respiratory and Critical Care Medicine. 194: 661-671. PMID 27628077 DOI: 10.1164/Rccm.201604-0898Up |
0.393 |
|
| 2016 |
Jakubek Y, Lang W, Vattathil S, Garcia M, Xu L, Huang L, Yoo SY, Shen L, Lu W, Chow CW, Weber Z, Davies G, Huang J, Behrens C, Kalhor N, ... Spira AE, et al. Genomic landscape established by allelic imbalance in the cancerization field of a normal appearing airway. Cancer Research. PMID 27216194 DOI: 10.1158/0008-5472.Can-15-3064 |
0.389 |
|
| 2016 |
Ferguson JS, Van Wert R, Choi Y, Rosenbluth MJ, Smith KP, Huang J, Spira A. Impact of a bronchial genomic classifier on clinical decision making in patients undergoing diagnostic evaluation for lung cancer. Bmc Pulmonary Medicine. 16: 66. PMID 27184093 DOI: 10.1186/S12890-016-0217-1 |
0.382 |
|
| 2016 |
Kusko RL, Brothers Ii JF, Tedrow J, Pandit K, Huleihel L, Perdomo C, Liu G, Juan-Guardela B, Kass D, Zhang S, Lenburg M, Martinez F, Quackenbush J, Sciurba F, Limper A, ... ... Spira A, et al. Integrated Genomics Reveals Convergent Transcriptomic Networks Underlying COPD and IPF. American Journal of Respiratory and Critical Care Medicine. PMID 27104832 DOI: 10.1164/Rccm.201510-2026Oc |
0.58 |
|
| 2016 |
Kadara H, Scheet P, Wistuba II, Spira AE. Early events in the molecular pathogenesis of lung cancer. Cancer Prevention Research (Philadelphia, Pa.). PMID 27006378 DOI: 10.1158/1940-6207.Capr-15-0400 |
0.441 |
|
| 2016 |
Vachani A, Whitney DH, Parsons EC, Lenburg M, Ferguson JS, Silvestri GA, Spira A. Clinical Utility of a Bronchial Genomic Classifier in Patients with Suspected Lung Cancer. Chest. PMID 26896702 DOI: 10.1016/J.Chest.2016.02.636 |
0.407 |
|
| 2016 |
Campbell JD, Mazzilli SA, Reid ME, Dhillon SS, Platero S, Beane J, Spira AE. The Case for a Pre-Cancer Genome Atlas (PCGA). Cancer Prevention Research (Philadelphia, Pa.). 9: 119-24. PMID 26839336 DOI: 10.1158/1940-6207.Capr-16-0024 |
0.656 |
|
| 2016 |
Grimes BS, Krysan K, Tran LM, Park SJ, Aberle DR, Spira AE, Dubinett SM. Indolence versus aggression in non-small cell lung cancer: defining heterogeneity to impact clinical outcomes Translational Cancer Research. 5. DOI: 10.21037/11283 |
0.348 |
|
| 2016 |
Mazzilli SA, Tassinari A, Gethalter Y, Lui G, Pine M, Lam S, Reid M, Platero S, Lenburg M, Spira A, Beane J. Abstract 896: The airway field of injury reflects gene expression changes associated with the presence of lung squamous premalignant lesions Cancer Research. 76: 896-896. DOI: 10.1158/1538-7445.Am2016-896 |
0.691 |
|
| 2016 |
Campbell JD, Perdomo C, Mazzilli S, Geshalter Y, Dhillon SS, Liu G, Zhang S, Lin H, Vick J, Moy C, Johnson E, Meyerson M, Platero S, Lenburg M, Reid M, ... Spira A, et al. Abstract 895: Genomic characterization of premalignant lung squamous cell carcinoma lesions Cancer Research. 76: 895-895. DOI: 10.1158/1538-7445.Am2016-895 |
0.731 |
|
| 2016 |
Moses E, Wang T, Jackson GR, Corbett S, Drizik E, Brooks D, O’Connor G, Perdomo C, Dubinett S, Hayden P, Lenburg ME, Spira A. Abstract 4502: Molecular impact of in vitro exposure to electronic cigarette vapor in human bronchial epithelium Cancer Research. 76: 4502-4502. DOI: 10.1158/1538-7445.Am2016-4502 |
0.304 |
|
| 2016 |
Pavel AB, Campbell J, Liu G, Zhang S, Liu H, Xiao J, Porta K, Whitney D, Dubinett S, Elashoff D, Lenburg M, Spira A. Abstract 1954: microRNA expression in bronchial epithelium for lung cancer detection Cancer Research. 76: 1954-1954. DOI: 10.1158/1538-7445.Am2016-1954 |
0.379 |
|
| 2016 |
Mascaux C, Angelova M, Beane J, Hijazi K, Antoine G, Gallo KW, Ninane V, Burny A, Sculier J, Spira A, Galon J. Abstract 1419: Characterization of the evolution of immune response in lung squamous carcinogenesis Cancer Research. 76: 1419-1419. DOI: 10.1158/1538-7445.Am2016-1419 |
0.701 |
|
| 2016 |
Van Wert R, Ferguson J, Choi Y, Rosenbluth M, Spira A. Impact of a Bronchial Genomic Classifier for Lung Cancer on Reducing Invasive Procedure Recommendations Across Variations in Pulmonology Practices Chest. 150: 732A. DOI: 10.1016/j.chest.2016.08.827 |
0.329 |
|
| 2016 |
Becker E, Lam S, van den Berge M, Liu G, Zhang X, Alekseyev Y, Spira A, Lenburg M, Steiling K. Predicting Lung Function Decline in COPD Using Bronchial Airway Gene Expression Chest. 150: 912A. DOI: 10.1016/J.Chest.2016.08.1012 |
0.399 |
|
| 2015 |
Ou SI, Ahn JS, De Petris L, Govindan R, Yang JC, Hughes B, Lena H, Moro-Sibilot D, Bearz A, Ramirez SV, Mekhail T, Spira A, Bordogna W, Balas B, Morcos PN, et al. Alectinib in Crizotinib-Refractory ALK-Rearranged Non-Small-Cell Lung Cancer: A Phase II Global Study. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. PMID 26598747 DOI: 10.1200/JCO.2015.63.9443 |
0.317 |
|
| 2015 |
Wang TW, Vermeulen RC, Hu W, Liu G, Xiao X, Alekseyev Y, Xu J, Reiss B, Steiling K, Downward GS, Silverman DT, Wei F, Wu G, Li J, Lenburg ME, ... ... Spira A, et al. Gene-expression profiling of buccal epithelium among nonsmoking women exposed to household air pollution from smoky coal. Carcinogenesis. PMID 26468118 DOI: 10.1093/Carcin/Bgv150 |
0.381 |
|
| 2015 |
Spira A, Halmos B, Powell CA. Update in Lung Cancer 2014. American Journal of Respiratory and Critical Care Medicine. 192: 283-94. PMID 26230235 DOI: 10.1164/Rccm.201504-0756Up |
0.4 |
|
| 2015 |
Silvestri GA, Vachani A, Whitney D, Elashoff M, Porta Smith K, Ferguson JS, Parsons E, Mitra N, Brody J, Lenburg ME, Spira A. A Bronchial Genomic Classifier for the Diagnostic Evaluation of Lung Cancer. The New England Journal of Medicine. 373: 243-51. PMID 25981554 DOI: 10.1056/Nejmoa1504601 |
0.438 |
|
| 2015 |
Sze MA, Dimitriu PA, Suzuki M, McDonough JE, Campbell JD, Brothers JF, Erb-Downward JR, Huffnagle GB, Hayashi S, Elliott WM, Cooper J, Sin DD, Lenburg ME, Spira A, Mohn WW, et al. The Host Response to the Lung Microbiome in Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine. PMID 25945594 DOI: 10.1164/Rccm.201502-0223Oc |
0.338 |
|
| 2015 |
Whitney DH, Elashoff MR, Porta-Smith K, Gower AC, Vachani A, Ferguson JS, Silvestri GA, Brody JS, Lenburg ME, Spira A. Derivation of a bronchial genomic classifier for lung cancer in a prospective study of patients undergoing diagnostic bronchoscopy. Bmc Medical Genomics. 8: 18. PMID 25944280 DOI: 10.1186/S12920-015-0091-3 |
0.486 |
|
| 2015 |
Gesthalter YB, Vick J, Steiling K, Spira A. Translating the transcriptome into tools for the early detection and prevention of lung cancer. Thorax. 70: 476-81. PMID 25628310 DOI: 10.1136/Thoraxjnl-2014-206605 |
0.379 |
|
| 2015 |
Yoo S, Takikawa S, Geraghty P, Argmann C, Campbell J, Lin L, Huang T, Tu Z, Foronjy RF, Feronjy R, Spira A, Schadt EE, Powell CA, Zhu J. Integrative analysis of DNA methylation and gene expression data identifies EPAS1 as a key regulator of COPD. Plos Genetics. 11: e1004898. PMID 25569234 DOI: 10.1371/Journal.Pgen.1004898 |
0.376 |
|
| 2015 |
Campbell JD, Liu G, Luo L, Xiao J, Gerrein J, Juan-Guardela B, Tedrow J, Alekseyev YO, Yang IV, Correll M, Geraci M, Quackenbush J, Sciurba F, Schwartz DA, Kaminski N, ... ... Spira A, et al. Assessment of microRNA differential expression and detection in multiplexed small RNA sequencing data. Rna (New York, N.Y.). 21: 164-71. PMID 25519487 DOI: 10.1261/Rna.046060.114 |
0.603 |
|
| 2015 |
Billatos E, Gesthalter Y, ten Hacken N, Postma D, Heijink I, Timens W, Brandsma C, Faiz A, Berge M, Lenburg M, Spira A. The Impact of Acute Smoking on Airway Gene-Expression Chest. 148: 746A. DOI: 10.1378/Chest.2280491 |
0.328 |
|
| 2015 |
Vachani A, Silvestri G, Whitney D, Ferguson J, Porta K, Parsons E, Brody J, Lenburg M, Spira A. Prospective Validation of a Bronchial Genomic Classifier for Lung Cancer in Patients Undergoing Diagnostic Bronchoscopy: The AEGIS Trials Chest. 148: 544A. DOI: 10.1378/Chest.2280365 |
0.348 |
|
| 2015 |
Spira A, Halmos B, Powell CA. Update in lung cancer 2014 American Journal of Respiratory and Critical Care Medicine. 192: 283-294. DOI: 10.1164/rccm.201504-0756UP |
0.393 |
|
| 2015 |
Mazzilli SA, Liu G, Zhang X, Si H, Lam S, Lenburg M, Spira A, Beane JE. Abstract A11: Airway gene expression indicates an increase in oxidative phosphorylation in the field of injury of individuals with premalignant lesions Cancer Prevention Research. 8. DOI: 10.1158/1940-6215.Prev-14-A11 |
0.71 |
|
| 2015 |
Perez-Rogers JF, Gerrein J, Anderlind C, Kusko RL, Campbell JD, Wang TW, Porta K, Whitney D, Spira A, Lenburg M. Abstract A1-66: Leveraging Gene Expression in the Bronchial Airway to Develop a Nasal Biomarker for Early Detection of Lung Cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Transcagen-A1-66 |
0.501 |
|
| 2015 |
Tassinari A, Zhang B, Steiling K, Whitney D, Porta K, Lam S, Lenburg M, Spira A, Beane J. Abstract B1-17: Airway gene-coexpression network rewiring in the presence of bronchial dysplasia and lung cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Compsysbio-B1-17 |
0.696 |
|
| 2015 |
Pavel AB, Campbell JD, Liu G, Zhang S, Liu H, Luo L, Xiao J, Porta K, Whitney D, Dubinett S, Elashoff D, Lenburg ME, Spira A. Abstract 3077: Dysregulation of microRNA-mRNA regulatory networks in the bronchial airway epithelium of smokers with lung cancer Cancer Research. 75: 3077-3077. DOI: 10.1158/1538-7445.Am2015-3077 |
0.486 |
|
| 2015 |
Beane JE, Campbell J, Moy C, Perdomo C, Schaffer M, Mazzilli S, Geshalter Y, Kantrowitz J, Zhang L, Jenkins D, Pine MB, Dhillon S, Liu G, Liu H, Zhang S, ... ... Spira A, et al. Abstract 2878: Development of the pre-cancer genome atlas (PCGA) for squamous cell lung carcinoma Cancer Research. 75: 2878-2878. DOI: 10.1158/1538-7445.Am2015-2878 |
0.743 |
|
| 2015 |
Perez-Rogers J, Gerrein J, Anderlind C, Xiao X, Liu H, Kusko R, Campbell J, Wang T, Alekseyev Y, Liu G, Porta K, Whitney D, Spira A, Lenburg M. Abstract 1574: Leveraging bronchial airway gene expression to develop a nasal biomarker for lung cancer detection Cancer Research. 75: 1574-1574. DOI: 10.1158/1538-7445.Am2015-1574 |
0.496 |
|
| 2014 |
Yang IV, Pedersen BS, Rabinovich E, Hennessy CE, Davidson EJ, Murphy E, Guardela BJ, Tedrow JR, Zhang Y, Singh MK, Correll M, Schwarz MI, Geraci M, Sciurba FC, Quackenbush J, ... Spira A, et al. Relationship of DNA methylation and gene expression in idiopathic pulmonary fibrosis. American Journal of Respiratory and Critical Care Medicine. 190: 1263-72. PMID 25333685 DOI: 10.1164/Rccm.201408-1452Oc |
0.322 |
|
| 2014 |
Lamontagne M, Timens W, Hao K, Bossé Y, Laviolette M, Steiling K, Campbell JD, Couture C, Conti M, Sherwood K, Hogg JC, Brandsma CA, van den Berge M, Sandford A, Lam S, ... ... Spira A, et al. Genetic regulation of gene expression in the lung identifies CST3 and CD22 as potential causal genes for airflow obstruction. Thorax. 69: 997-1004. PMID 25182044 DOI: 10.1136/Thoraxjnl-2014-205630 |
0.4 |
|
| 2014 |
Wang X, Pittman GS, Bandele OJ, Bischof JJ, Liu G, Brothers JF, Spira A, Bell DA. Linking polymorphic p53 response elements with gene expression in airway epithelial cells of smokers and cancer risk. Human Genetics. 133: 1467-76. PMID 25179167 DOI: 10.1007/S00439-014-1483-8 |
0.389 |
|
| 2014 |
Kathuria H, Gesthalter Y, Spira A, Brody JS, Steiling K. Updates and controversies in the rapidly evolving field of lung cancer screening, early detection, and chemoprevention. Cancers. 6: 1157-79. PMID 24840047 DOI: 10.3390/Cancers6021157 |
0.425 |
|
| 2014 |
Mok TS, Geater SL, Iannotti N, Thongprasert S, Spira A, Smith D, Lee V, Lim WT, Reyderman L, Wang B, Gopalakrishna P, Garzon F, Xu L, Reynolds C. Randomized phase II study of two intercalated combinations of eribulin mesylate and erlotinib in patients with previously treated advanced non-small-cell lung cancer. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 25: 1578-84. PMID 24827127 DOI: 10.1093/Annonc/Mdu174 |
0.322 |
|
| 2014 |
Dijkstra AE, Smolonska J, van den Berge M, Wijmenga C, Zanen P, Luinge MA, Platteel M, Lammers JW, Dahlback M, Tosh K, Hiemstra PS, Sterk PJ, Spira A, Vestbo J, Nordestgaard BG, et al. Susceptibility to chronic mucus hypersecretion, a genome wide association study. Plos One. 9: e91621. PMID 24714607 DOI: 10.1371/Journal.Pone.0091621 |
0.31 |
|
| 2014 |
Ooi AT, Gower AC, Zhang KX, Vick JL, Hong L, Nagao B, Wallace WD, Elashoff DA, Walser TC, Dubinett SM, Pellegrini M, Lenburg ME, Spira A, Gomperts BN. Molecular profiling of premalignant lesions in lung squamous cell carcinomas identifies mechanisms involved in stepwise carcinogenesis. Cancer Prevention Research (Philadelphia, Pa.). 7: 487-95. PMID 24618292 DOI: 10.1158/1940-6207.Capr-13-0372 |
0.426 |
|
| 2014 |
Christmann RB, Sampaio-Barros P, Stifano G, Borges CL, de Carvalho CR, Kairalla R, Parra ER, Spira A, Simms R, Capellozzi VL, Lafyatis R. Association of Interferon- and transforming growth factor β-regulated genes and macrophage activation with systemic sclerosis-related progressive lung fibrosis. Arthritis & Rheumatology (Hoboken, N.J.). 66: 714-25. PMID 24574232 DOI: 10.1002/Art.38288 |
0.389 |
|
| 2014 |
Kadara H, Fujimoto J, Yoo SY, Maki Y, Gower AC, Kabbout M, Garcia MM, Chow CW, Chu Z, Mendoza G, Shen L, Kalhor N, Hong WK, Moran C, Wang J, ... Spira A, et al. Transcriptomic architecture of the adjacent airway field cancerization in non-small cell lung cancer. Journal of the National Cancer Institute. 106: dju004. PMID 24563515 DOI: 10.1093/Jnci/Dju004 |
0.42 |
|
| 2014 |
Butts C, Socinski MA, Mitchell PL, Thatcher N, Havel L, Krzakowski M, Nawrocki S, Ciuleanu TE, Bosquée L, Trigo JM, Spira A, Tremblay L, Nyman J, Ramlau R, Wickart-Johansson G, et al. Tecemotide (L-BLP25) versus placebo after chemoradiotherapy for stage III non-small-cell lung cancer (START): a randomised, double-blind, phase 3 trial. The Lancet. Oncology. 15: 59-68. PMID 24331154 DOI: 10.1016/S1470-2045(13)70510-2 |
0.36 |
|
| 2014 |
Vucic EA, Chari R, Thu KL, Wilson IM, Cotton AM, Kennett JY, Zhang M, Lonergan KM, Steiling K, Brown CJ, McWilliams A, Ohtani K, Lenburg ME, Sin DD, Spira A, et al. DNA methylation is globally disrupted and associated with expression changes in chronic obstructive pulmonary disease small airways. American Journal of Respiratory Cell and Molecular Biology. 50: 912-22. PMID 24298892 DOI: 10.1165/Rcmb.2013-0304Oc |
0.323 |
|
| 2014 |
van den Berge M, Steiling K, Timens W, Hiemstra PS, Sterk PJ, Heijink IH, Liu G, Alekseyev YO, Lenburg ME, Spira A, Postma DS. Airway gene expression in COPD is dynamic with inhaled corticosteroid treatment and reflects biological pathways associated with disease activity. Thorax. 69: 14-23. PMID 23925644 DOI: 10.1136/Thoraxjnl-2012-202878 |
0.301 |
|
| 2014 |
Jiwani A, Maple E, Schnall M, Mahon I, Apgar C, Browning R, More K, Morris M, Parrish J, Atwood C, Battaile J, Garshick E, Gatsonis C, Goldstein R, Kieth R, ... ... Spira A, et al. Detection and Validation of Molecular Biomarkers for the Early Detection of Lung Cancer Among Military and Veteran Populations: The DECAMP Consortium Chest. 146: 590A. DOI: 10.1378/Chest.1993874 |
0.308 |
|
| 2014 |
Park SJ, Walser TC, Perdomo C, Wang T, Hong L, Pagano PC, Liclican EL, Krysan K, Larsen JE, Fishbein MC, Minna JD, Lenburg ME, Spira A, Dubinett SM. Abstract 932: The impact of e-cigarette exposure on pulmonary epithelium gene expression and transformation Cancer Research. 74: 932-932. DOI: 10.1158/1538-7445.Am2014-932 |
0.442 |
|
| 2014 |
Kusko R, Garrison C, Wang T, Campbell J, Perez-Rogers J, Luo L, Beane J, Liu G, Kadara H, Belinsky S, Lenburg ME, Spira A. Abstract 3554: Gene and miRNA expression networks specific to never smoker lung adenocarcinoma Cancer Research. 74: 3554-3554. DOI: 10.1158/1538-7445.Am2014-3554 |
0.702 |
|
| 2014 |
Hijazi K, Bomalysz B, Steiling K, Xiao J, Liu G, Alekseyev Y, Yves MD, Hertsgaard LA, Jensen J, Vogel RI, Hatsukami D, O'Connor G, Brooks DR, Beane J, Spira A. Abstract 2354: Nasal gene expression reflects the physiologic response to potentially reduced exposure products Cancer Research. 74: 2354-2354. DOI: 10.1158/1538-7445.Am2014-2354 |
0.67 |
|
| 2014 |
Kusko R, Anderlind C, Wang G, Zhang S, Wallace WD, Wasler T, Ebright M, Garcia MM, Eisenberg R, Lee G, Liu G, Elashoff D, Kalhor N, Moran C, Mehran R, ... ... Spira A, et al. Abstract 2352: Mapping the airway-wide molecular field of injury in smokers with lung cancer Cancer Research. 74: 2352-2352. DOI: 10.1158/1538-7445.Am2014-2352 |
0.52 |
|
| 2014 |
Maki Y, Fujimoto J, Yoo S, Garcia M, Gower A, Shen L, Chow C, Behrens C, Kalhor N, Moran C, Wang J, Spira A, Coombes KR, Wistuba II, Kadara H. Abstract 1597: Transcriptomic architecture of the field of cancerization in the adjacent normal-appearing airway: Early mechanisms in lung carcinogenesis Cancer Research. 74: 1597-1597. DOI: 10.1158/1538-7445.Am2014-1597 |
0.454 |
|
| 2014 |
Pavel A, Campbell J, Liu G, Zhang S, Liu H, Dubinett S, Elashoff D, Porta K, Whitney D, Lenburg M, Spira A. Abstract 1485: Biomarker development for lung cancer diagnosis using integrative microRNA and gene expression networks Cancer Research. 74: 1485-1485. DOI: 10.1158/1538-7445.Am2014-1485 |
0.357 |
|
| 2014 |
Tassinari A, Whitney D, Porta K, Lenburg M, Spira A, Beane J. Abstract 1414: Race-associated variation in the airway transcriptome response to cigarette smoke Cancer Research. 74: 1414-1414. DOI: 10.1158/1538-7445.Am2014-1414 |
0.721 |
|
| 2013 |
Christenson SA, Brandsma CA, Campbell JD, Knight DA, Pechkovsky DV, Hogg JC, Timens W, Postma DS, Lenburg M, Spira A. miR-638 regulates gene expression networks associated with emphysematous lung destruction. Genome Medicine. 5: 114. PMID 24380442 DOI: 10.1186/Gm519 |
0.357 |
|
| 2013 |
Steiling K, Lenburg ME, Spira A. Personalized management of chronic obstructive pulmonary disease via transcriptomic profiling of the airway and lung. Annals of the American Thoracic Society. 10: S190-6. PMID 24313772 DOI: 10.1513/Annalsats.201306-190Aw |
0.316 |
|
| 2013 |
Perdomo C, Campbell JD, Gerrein J, Tellez CS, Garrison CB, Walser TC, Drizik E, Si H, Gower AC, Vick J, Anderlind C, Jackson GR, Mankus C, Schembri F, O'Hara C, ... ... Spira A, et al. MicroRNA 4423 is a primate-specific regulator of airway epithelial cell differentiation and lung carcinogenesis. Proceedings of the National Academy of Sciences of the United States of America. 110: 18946-51. PMID 24158479 DOI: 10.1073/Pnas.1220319110 |
0.431 |
|
| 2013 |
Dubinett SM, Spira A. Challenge and opportunity of targeted lung cancer chemoprevention. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 4169-71. PMID 24002497 DOI: 10.1200/Jco.2013.51.2400 |
0.417 |
|
| 2013 |
Brothers JF, Hijazi K, Mascaux C, El-Zein RA, Spitz MR, Spira A. Bridging the clinical gaps: genetic, epigenetic and transcriptomic biomarkers for the early detection of lung cancer in the post-National Lung Screening Trial era. Bmc Medicine. 11: 168. PMID 23870182 DOI: 10.1186/1741-7015-11-168 |
0.387 |
|
| 2013 |
Zhang X, Lenburg ME, Spira A. Comparison of nasal epithelial smoking-induced gene expression on Affymetrix Exon 1.0 and Gene 1.0 ST arrays. Thescientificworldjournal. 2013: 951416. PMID 23476154 DOI: 10.1155/2013/951416 |
0.336 |
|
| 2013 |
Steiling K, van den Berge M, Hijazi K, Florido R, Campbell J, Liu G, Xiao J, Zhang X, Duclos G, Drizik E, Si H, Perdomo C, Dumont C, Coxson HO, Alekseyev YO, ... ... Spira A, et al. A dynamic bronchial airway gene expression signature of chronic obstructive pulmonary disease and lung function impairment. American Journal of Respiratory and Critical Care Medicine. 187: 933-42. PMID 23471465 DOI: 10.1164/Rccm.201208-1449Oc |
0.362 |
|
| 2013 |
Jean JC, George E, Kaestner KH, Brown LA, Spira A, Joyce-Brady M. Transcription factor Klf4, induced in the lung by oxygen at birth, regulates perinatal fibroblast and myofibroblast differentiation. Plos One. 8: e54806. PMID 23372771 DOI: 10.1371/Journal.Pone.0054806 |
0.361 |
|
| 2013 |
Gomperts BN, Walser TC, Spira A, Dubinett SM. Enriching the molecular definition of the airway "field of cancerization:" establishing new paradigms for the patient at risk for lung cancer. Cancer Prevention Research (Philadelphia, Pa.). 6: 4-7. PMID 23233734 DOI: 10.1158/1940-6207.Capr-12-0470 |
0.434 |
|
| 2013 |
Park SJ, Walser TC, Perdomo C, Pagano PP, Brass D, Liclican EL, Krysan K, Lenburg ME, Spira A, Dubinett SM. Abstract C58: The gene expression and functional impact of E-cigarette exposure on pulmonary epithelial transformation Cancer Prevention Research. 6. DOI: 10.1158/1940-6215.Prev-13-C58 |
0.339 |
|
| 2013 |
Maki Y, Fujimoto J, Yoo S, Gower A, Shen L, Garcia MM, Kabbout M, Chow C, Hong WK, Kalhor N, Wang J, Moran C, Spira A, Coombes KR, Wistuba II, et al. Abstract 2367: Transcriptomic architecture of the airway field cancerization in early-stage non-small cell lung cancer . Cancer Research. 73: 2367-2367. DOI: 10.1158/1538-7445.Am2013-2367 |
0.482 |
|
| 2013 |
Wang T, Campbell J, Kusko R, Luo L, Tellez C, Liu G, Xiao J, Lenburg M, Belinsky S, Spira A. Abstract 1948: Shared and distinct microRNA-expression alterations in lung adenocarcinoma from smokers vs. nonsmokers. Cancer Research. 73: 1948-1948. DOI: 10.1158/1538-7445.Am2013-1948 |
0.373 |
|
| 2013 |
Wang TW, Lan Q, Krystyna B, Rothman N, Florido R, Hu W, Steiling K, Liu G, Xiao J, Alekseyev Y, Xu J, Wei F, Hosgood HD, Reiss B, Downward G, ... ... Spira A, et al. Abstract 112: Transcriptomic changes in the oral mucosal epithelium reflect the physiologic response to indoor burning of solid fuels. Cancer Research. 73: 112-112. DOI: 10.1158/1538-7445.Am2013-112 |
0.405 |
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| 2013 |
Ooi AT, Gower A, Zhang K, Vick J, Hong L, Fishbein M, Nagao B, Wallace WD, Elashoff D, Lenburg M, Dubinett S, Spira A, Gomperts B. Abstract 1063: Examining early events in carcinogenesis by profiling premalignant lesions in the airways of patients with lung squamous cell carcinomas. Cancer Research. 73: 1063-1063. DOI: 10.1158/1538-7445.Am2013-1063 |
0.491 |
|
| 2013 |
Grayson P, Steiling K, Monach P, Platt M, Xiao J, Zhang X, Alekseyev Y, Moni S, Spira A, Merkel P. Upper airway gene expression profiling in granulomatosis with polyangiitis Presse Medicale. 42: 660-661. DOI: 10.1016/J.Lpm.2013.02.025 |
0.303 |
|
| 2012 |
Beane J, Cheng L, Soldi R, Zhang X, Liu G, Anderlind C, Lenburg ME, Spira A, Bild AH. SIRT1 pathway dysregulation in the smoke-exposed airway epithelium and lung tumor tissue. Cancer Research. 72: 5702-11. PMID 22986747 DOI: 10.1158/0008-5472.Can-12-1043 |
0.735 |
|
| 2012 |
Campbell JD, McDonough JE, Zeskind JE, Hackett TL, Pechkovsky DV, Brandsma CA, Suzuki M, Gosselink JV, Liu G, Alekseyev YO, Xiao J, Zhang X, Hayashi S, Cooper JD, Timens W, ... ... Spira A, et al. A gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK. Genome Medicine. 4: 67. PMID 22937864 DOI: 10.1186/Gm367 |
0.364 |
|
| 2012 |
Tagne JB, Gupta S, Gower AC, Shen SS, Varma S, Lakshminarayanan M, Cao Y, Spira A, Volkert TL, Ramirez MI. Genome-wide analyses of Nkx2-1 binding to transcriptional target genes uncover novel regulatory patterns conserved in lung development and tumors. Plos One. 7: e29907. PMID 22242187 DOI: 10.1371/Journal.Pone.0029907 |
0.395 |
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| 2012 |
Whitney D, Luo J, Porta K, Lenburg M, Brody J, Ernst A, Vachani A, Ferguson J, Silvestri G, Spira A. Bronchial Airway Gene-Expression Testing Improves the Diagnostic Yield of Bronchoscopy for Lung Cancer: Results of the AEGIS Trial Chest. 142: 1025A. DOI: 10.1378/Chest.1450411 |
0.429 |
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| 2012 |
Campbell JD, Luo L, Liu G, Xiao J, Gerrein J, Guardela BJ, Tedrow J, Aleksyev YO, Yang IV, Correll M, Geraci M, Quackenbush J, Sciurba F, Schwartz DA, Kaminski N, ... ... Spira A, et al. Characterizing the small RNA transcriptome associated with COPD and ILD using next-generation sequencing Bmc Proceedings. 6. DOI: 10.1186/1753-6561-6-S6-P6 |
0.664 |
|
| 2012 |
Brothers J, Kusko R, Liu G, Luo L, Guardela BJ, Tedrow J, Alekesyev Y, Yang IV, Correll M, Geraci M, Quackenbush J, Sciurba F, Sebastiani P, Lenburg M, Kaminski N, ... ... Spira A, et al. Moving beyond gene expression: identification of lung-disease-associated novel transcripts and alternative splicing by RNA sequencing Bmc Proceedings. 6. DOI: 10.1186/1753-6561-6-S6-P4 |
0.684 |
|
| 2012 |
Wang TW, Campbell JD, Luo L, Liu G, Xiao J, Lenburg ME, Belinsky SA, Spira A. Deep sequencing of the microRNA transcriptome in current, former, and never smokers with lung adenocarcinoma Bmc Proceedings. 6. DOI: 10.1186/1753-6561-6-S6-P38 |
0.421 |
|
| 2012 |
Kusko RL, Brothers J, Liu G, Luo L, Guardela BJ, Tedrow J, Aleksyev Y, Yang IV, Correll M, Geraci M, Quackenbush J, Sciurba F, Lenburg M, Schwartz DA, Beane J, ... ... Spira A, et al. Comprehensive genomic profiling of the lung transcriptome in emphysema and idiopathic pulmonary fibrosis using RNA-Seq Bmc Proceedings. 6. DOI: 10.1186/1753-6561-6-S6-P21 |
0.692 |
|
| 2012 |
Hijazi K, Malyszko B, Zhang X, Liu G, Alekseyev Y, Dumas Y, Hertsgaard L, Jenson J, Rohde C, Hatsukami DK, Hecht SS, Brooks DR, O'Connor G, Lenburg M, Steiling K, ... Spira A, et al. Abstract B07: Nasal epithelial gene expression profiles reflect dynamic biological response to smoking cessation Cancer Prevention Research. 5: B07-B07. DOI: 10.1158/1940-6207.Prev-12-B07 |
0.356 |
|
| 2012 |
Perdomo C, Campbell J, Gerrein J, Tellez C, Gower A, Vick J, Garrison C, Anderlind C, Jackson GR, Schembri F, Gomperts BN, Hayden P, Belinsky SA, Lenburg ME, Spira A. Abstract 3173: Identification of miR-4423 as a primate-specific microRNA highly expressed in airway epithelium and associated with lung cancer Cancer Research. 72: 3173-3173. DOI: 10.1158/1538-7445.Am2012-3173 |
0.463 |
|
| 2012 |
Campbell JD, Luo L, Xiao J, Liu G, Aleksyev Y, Elashoff D, Dubinett SM, Lenburg ME, Spira A. Abstract 3154: Sequencing of the small RNA transcriptome in cytologically normal bronchial airway epithelium of smokers with and without lung cancer Cancer Research. 72: 3154-3154. DOI: 10.1158/1538-7445.Am2012-3154 |
0.52 |
|
| 2012 |
Beane JE, Hijazi K, Liu G, Zhang X, Xiao J, Lam S, Lenburg M, Spira A. Abstract 1607: Airway gene expression alterations associated with lung cancer chemoprevention using green tea extract Cancer Research. 72: 1607-1607. DOI: 10.1158/1538-7445.Am2012-1607 |
0.722 |
|
| 2011 |
Beane J, Vick J, Schembri F, Anderlind C, Gower A, Campbell J, Luo L, Zhang XH, Xiao J, Alekseyev YO, Wang S, Levy S, Massion PP, Lenburg M, Spira A. Characterizing the impact of smoking and lung cancer on the airway transcriptome using RNA-Seq. Cancer Prevention Research (Philadelphia, Pa.). 4: 803-17. PMID 21636547 DOI: 10.1158/1940-6207.Capr-11-0212 |
0.736 |
|
| 2011 |
Gower AC, Steiling K, Brothers JF, Lenburg ME, Spira A. Transcriptomic studies of the airway field of injury associated with smoking-related lung disease. Proceedings of the American Thoracic Society. 8: 173-9. PMID 21543797 DOI: 10.1513/pats.201011-066MS |
0.426 |
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| 2011 |
Gomperts BN, Spira A, Massion PP, Walser TC, Wistuba II, Minna JD, Dubinett SM. Evolving concepts in lung carcinogenesis. Seminars in Respiratory and Critical Care Medicine. 32: 32-43. PMID 21500122 DOI: 10.1055/S-0031-1272867 |
0.426 |
|
| 2011 |
Campbell JD, Spira A, Lenburg ME. Applying gene expression microarrays to pulmonary disease. Respirology (Carlton, Vic.). 16: 407-18. PMID 21299687 DOI: 10.1111/J.1440-1843.2011.01942.X |
0.304 |
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| 2011 |
Boelens MC, Gustafson AM, Postma DS, Kok K, van der Vries G, van der Vlies P, Spira A, Lenburg ME, Geerlings M, Sietsma H, Timens W, van den Berg A, Groen HJ. A chronic obstructive pulmonary disease related signature in squamous cell lung cancer. Lung Cancer (Amsterdam, Netherlands). 72: 177-83. PMID 20832896 DOI: 10.1016/J.Lungcan.2010.08.014 |
0.327 |
|
| 2011 |
Gerrein J, Perdomo C, Campbell JD, Vick J, Gower A, Anderlind C, Schembri F, Lenburg M, Spira A. Abstract 3989: Discovery of a novel airway microRNA associated with lung cancer using next generation sequencing Cellular and Molecular Biology. 71: 3989-3989. DOI: 10.1158/1538-7445.Am2011-3989 |
0.406 |
|
| 2010 |
Ooi AT, Mah V, Nickerson DW, Gilbert JL, Ha VL, Hegab AE, Horvath S, Alavi M, Maresh EL, Chia D, Gower AC, Lenburg ME, Spira A, Solis LM, Wistuba II, et al. Presence of a putative tumor-initiating progenitor cell population predicts poor prognosis in smokers with non-small cell lung cancer. Cancer Research. 70: 6639-48. PMID 20710044 DOI: 10.1158/0008-5472.Can-10-0455 |
0.416 |
|
| 2010 |
Wang X, Chorley BN, Pittman GS, Kleeberger SR, Brothers J, Liu G, Spira A, Bell DA. Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer. Plos One. 5: e11934. PMID 20689807 DOI: 10.1371/Journal.Pone.0011934 |
0.513 |
|
| 2010 |
Gustafson AM, Soldi R, Anderlind C, Scholand MB, Qian J, Zhang X, Cooper K, Walker D, McWilliams A, Liu G, Szabo E, Brody J, Massion PP, Lenburg ME, Lam S, ... ... Spira A, et al. Airway PI3K pathway activation is an early and reversible event in lung cancer development. Science Translational Medicine. 2: 26ra25. PMID 20375364 DOI: 10.1126/Scitranslmed.3000251 |
0.459 |
|
| 2010 |
Gomperts BN, Spira A, Elashoff DE, Dubinett SM. Lung cancer biomarkers: FISHing in the sputum for risk assessment and early detection. Cancer Prevention Research (Philadelphia, Pa.). 3: 420-3. PMID 20332300 DOI: 10.1158/1940-6207.Capr-10-0052 |
0.314 |
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| 2010 |
Spira A. Upper airway gene expression in smokers: the mouth as a "window to the soul" of lung carcinogenesis? Cancer Prevention Research (Philadelphia, Pa.). 3: 255-8. PMID 20179303 DOI: 10.1158/1940-6207.Capr-10-0013 |
0.437 |
|
| 2010 |
Zhang X, Sebastiani P, Liu G, Schembri F, Zhang X, Dumas YM, Langer EM, Alekseyev Y, O'Connor GT, Brooks DR, Lenburg ME, Spira A. Similarities and differences between smoking-related gene expression in nasal and bronchial epithelium. Physiological Genomics. 41: 1-8. PMID 19952278 DOI: 10.1152/Physiolgenomics.00167.2009 |
0.381 |
|
| 2010 |
Hazra S, Gardner BK, Krysan K, Walser TC, Larsen JE, Pertsemlidis A, Shay JW, Minna JD, Spira A, Dubinett SM. Abstract A31: The role of microRNA 125a‐3P in the pathogenesis of lung cancer Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-09-A31 |
0.425 |
|
| 2010 |
Ooi AT, Mah VH, Nickerson DW, Gilbert JL, Ha VL, Hegab AE, Horvath S, Alavi M, Maresh E, Chia D, Gower AC, Lenburg ME, Spira A, Walser T, Wallace WD, et al. Abstract 4299: Poor prognosis in smokers with non-small cell lung cancer correlates with the presence of a reparative progenitor cell population Cancer Research. 70: 4299-4299. DOI: 10.1158/1538-7445.Am10-4299 |
0.377 |
|
| 2010 |
Beane J, Gerrein J, Vick J, Gindin Y, Anderlind C, Levy S, Massion P, Schembri F, Lenburg M, Spira A. Abstract 1987: RNA-seq of the bronchial airway transcriptome identifies novel gene and microRNA expression changes associated with smoking and lung cancer Cancer Research. 70: 1987-1987. DOI: 10.1158/1538-7445.Am10-1987 |
0.734 |
|
| 2010 |
Kathuria H, Spira A, Brody J. Genomics in the Diagnosis and Management of Lung Cancer Essentials of Genomic and Personalized Medicine. 432-445. DOI: 10.1016/B978-0-12-374934-5.00034-9 |
0.471 |
|
| 2009 |
Steiling K, Lenburg ME, Spira A. Airway gene expression in chronic obstructive pulmonary disease. Proceedings of the American Thoracic Society. 6: 697-700. PMID 20008878 DOI: 10.1513/pats.200907-076DP |
0.334 |
|
| 2009 |
Steiling K, Kadar AY, Bergerat A, Flanigon J, Sridhar S, Shah V, Ahmad QR, Brody JS, Lenburg ME, Steffen M, Spira A. Comparison of proteomic and transcriptomic profiles in the bronchial airway epithelium of current and never smokers. Plos One. 4: e5043. PMID 19357784 DOI: 10.1371/Journal.Pone.0005043 |
0.352 |
|
| 2009 |
Beane J, Spira A, Lenburg ME. Clinical impact of high-throughput gene expression studies in lung cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 4: 109-18. PMID 19096318 DOI: 10.1097/Jto.0B013E31819151F8 |
0.708 |
|
| 2009 |
Kathuria H, Spira A, Brody J. Genomics of Lung Cancer Genomic and Personalized Medicine, Two-Vol Set. 856-868. DOI: 10.1016/B978-0-12-369420-1.00071-8 |
0.374 |
|
| 2008 |
Steiling K, Ryan J, Brody JS, Spira A. The field of tissue injury in the lung and airway. Cancer Prevention Research (Philadelphia, Pa.). 1: 396-403. PMID 19138985 DOI: 10.1158/1940-6207.Capr-08-0174 |
0.423 |
|
| 2008 |
Beane J, Sebastiani P, Whitfield TH, Steiling K, Dumas YM, Lenburg ME, Spira A. A prediction model for lung cancer diagnosis that integrates genomic and clinical features. Cancer Prevention Research (Philadelphia, Pa.). 1: 56-64. PMID 19138936 DOI: 10.1158/1940-6207.Capr-08-0011 |
0.709 |
|
| 2008 |
Zeskind JE, Lenburg ME, Spira A. Translating the COPD transcriptome: insights into pathogenesis and tools for clinical management. Proceedings of the American Thoracic Society. 5: 834-41. PMID 19017738 DOI: 10.1513/pats.200807-074TH |
0.436 |
|
| 2008 |
Sridhar S, Schembri F, Zeskind J, Shah V, Gustafson AM, Steiling K, Liu G, Dumas YM, Zhang X, Brody JS, Lenburg ME, Spira A. Smoking-induced gene expression changes in the bronchial airway are reflected in nasal and buccal epithelium. Bmc Genomics. 9: 259. PMID 18513428 DOI: 10.1186/1471-2164-9-259 |
0.412 |
|
| 2008 |
Millien G, Beane J, Lenburg M, Tsao PN, Lu J, Spira A, Ramirez MI. Characterization of the mid-foregut transcriptome identifies genes regulated during lung bud induction. Gene Expression Patterns : Gep. 8: 124-39. PMID 18023262 DOI: 10.1016/J.Modgep.2007.09.003 |
0.707 |
|
| 2007 |
Zhang X, Liu G, Lenburg ME, Spira A. Comparison of smoking-induced gene expression on Affymetrix Exon and 3'-based expression arrays. Genome Informatics. International Conference On Genome Informatics. 18: 247-57. PMID 18546492 DOI: 10.11234/Gi1990.18.247 |
0.397 |
|
| 2007 |
Beane J, Sebastiani P, Liu G, Brody JS, Lenburg ME, Spira A. Reversible and permanent effects of tobacco smoke exposure on airway epithelial gene expression. Genome Biology. 8: R201. PMID 17894889 DOI: 10.1186/Gb-2007-8-9-R201 |
0.652 |
|
| 2007 |
Spira A, Beane JE, Shah V, Steiling K, Liu G, Schembri F, Gilman S, Dumas YM, Calner P, Sebastiani P, Sridhar S, Beamis J, Lamb C, Anderson T, Gerry N, et al. Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer. Nature Medicine. 13: 361-6. PMID 17334370 DOI: 10.1038/Nm1556 |
0.752 |
|
| 2006 |
Brody JS, Spira A. State of the art. Chronic obstructive pulmonary disease, inflammation, and lung cancer. Proceedings of the American Thoracic Society. 3: 535-7. PMID 16921139 DOI: 10.1513/pats.200603-089MS |
0.44 |
|
| 2006 |
DeMeo D, Mariani T, Lange C, Lake S, Litonjua A, Celedón J, Reilly J, Chapman HA, Sparrow D, Spira A, Beane J, Pinto-Plata V, Speizer FE, Shapiro S, Weiss ST, et al. The SERPINE2 gene is associated with chronic obstructive pulmonary disease. Proceedings of the American Thoracic Society. 3: 502. PMID 16921128 DOI: 10.1513/pats.200603-070MS |
0.616 |
|
| 2006 |
Millien G, Spira A, Hinds A, Wang J, Williams MC, Ramirez MI. Alterations in gene expression in T1 alpha null lung: a model of deficient alveolar sac development. Bmc Developmental Biology. 6: 35. PMID 16869965 DOI: 10.1186/1471-213X-6-35 |
0.407 |
|
| 2006 |
Demeo D, Mariani T, Lange C, Srisuma S, Litonjua A, Celedon J, Lake S, Reilly J, Chapman H, Mecham B, Haley K, Sylvia J, Sparrow D, Spira A, Beane J, et al. The SERPINE2 gene is associated with chronic obstructive pulmonary disease Respiratory Medicine: Copd Update. 1: 143. DOI: 10.1016/J.Rmedu.2006.03.030 |
0.616 |
|
| 2005 |
Shah V, Sridhar S, Beane J, Brody JS, Spira A. SIEGE: Smoking Induced Epithelial Gene Expression Database. Nucleic Acids Research. 33: D573-9. PMID 15608264 DOI: 10.1093/Nar/Gki035 |
0.672 |
|
| 2004 |
Spira A, Beane J, Pinto-Plata V, Kadar A, Liu G, Shah V, Celli B, Brody JS. Gene expression profiling of human lung tissue from smokers with severe emphysema. American Journal of Respiratory Cell and Molecular Biology. 31: 601-10. PMID 15374838 DOI: 10.1165/Rcmb.2004-0273Oc |
0.727 |
|
| 2004 |
Spira A, Beane J, Shah V, Liu G, Schembri F, Yang X, Palma J, Brody JS. Effects of cigarette smoke on the human airway epithelial cell transcriptome. Proceedings of the National Academy of Sciences of the United States of America. 101: 10143-8. PMID 15210990 DOI: 10.1073/Pnas.0401422101 |
0.715 |
|
| 2004 |
Spira A, Schembri F, Beane J, Shah V, Liu G, Brody JS. Impact of cigarette smoke on the normal airway transcriptome. Chest. 125: 115S. PMID 15136455 DOI: 10.1378/Chest.125.5_Suppl.115S |
0.627 |
|
| 2004 |
Spira A, Beane J, Schembri F, Liu G, Ding C, Gilman S, Yang X, Cantor C, Brody JS. Noninvasive method for obtaining RNA from buccal mucosa epithelial cells for gene expression profiling. Biotechniques. 36: 484-7. PMID 15038164 DOI: 10.2144/04363Rn03 |
0.63 |
|
| 2003 |
Powell CA, Spira A, Derti A, DeLisi C, Liu G, Borczuk A, Busch S, Sahasrabudhe S, Chen Y, Sugarbaker D, Bueno R, Richards WG, Brody JS. Gene expression in lung adenocarcinomas of smokers and nonsmokers. American Journal of Respiratory Cell and Molecular Biology. 29: 157-62. PMID 12600827 DOI: 10.1165/Rcmb.2002-0183Rc |
0.47 |
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