William M. Saxton - Publications

Affiliations: 
Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Cell Biology, Neuroscience Biology, Genetics

45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Saxton WM, Lim A, Djagaeva I. Dissection and Direct Imaging of Axonal Transport in Drosophila Segmental Nerves. Methods in Molecular Biology (Clifton, N.J.). 2431: 367-384. PMID 35412287 DOI: 10.1007/978-1-0716-1990-2_19  0.618
2017 Lim A, Rechtsteiner A, Saxton WM. Two kinesins drive anterograde neuropeptide transport. Molecular Biology of the Cell. PMID 28904207 DOI: 10.1091/Mbc.E16-12-0820  0.679
2016 Monteith CE, Brunner ME, Djagaeva I, Bielecki AM, Deutsch JM, Saxton WM. A Mechanism for Cytoplasmic Streaming: Kinesin-Driven Alignment of Microtubules and Fast Fluid Flows. Biophysical Journal. 110: 2053-65. PMID 27166813 DOI: 10.1016/J.Bpj.2016.03.036  0.398
2016 Moua P, Fullerton D, Serbus LR, Warrior R, Saxton WM. Kinesin-1 tail autoregulation and microtubule-binding regions function in saltatory transport but not ooplasmic streaming. Development (Cambridge, England). 143: 1228. PMID 27048687 DOI: 10.1242/dev.136747  0.776
2012 Djagaeva I, Rose DJ, Lim A, Venter CE, Brendza KM, Moua P, Saxton WM. Three routes to suppression of the neurodegenerative phenotypes caused by kinesin heavy chain mutations. Genetics. 192: 173-83. PMID 22714410 DOI: 10.1534/Genetics.112.140798  0.576
2012 Saxton WM, Hollenbeck PJ. The axonal transport of mitochondria. Journal of Cell Science. 125: 2095-104. PMID 22619228 DOI: 10.1242/Jcs.053850  0.635
2012 Liu S, Sawada T, Lee S, Yu W, Silverio G, Alapatt P, Millan I, Shen A, Saxton W, Kanao T, Takahashi R, Hattori N, Imai Y, Lu B. Parkinson's disease-associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondria. Plos Genetics. 8: e1002537. PMID 22396657 DOI: 10.1371/Journal.Pgen.1002537  0.522
2011 Moua P, Fullerton D, Serbus LR, Warrior R, Saxton WM. Kinesin-1 tail autoregulation and microtubule-binding regions function in saltatory transport but not ooplasmic streaming. Development (Cambridge, England). 138: 1087-92. PMID 21307100 DOI: 10.1242/Dev.048645  0.824
2008 Barkus RV, Klyachko O, Horiuchi D, Dickson BJ, Saxton WM. Identification of an axonal kinesin-3 motor for fast anterograde vesicle transport that facilitates retrograde transport of neuropeptides. Molecular Biology of the Cell. 19: 274-83. PMID 17989365 DOI: 10.1091/Mbc.E07-03-0261  0.792
2007 Horiuchi D, Collins CA, Bhat P, Barkus RV, Diantonio A, Saxton WM. Control of a kinesin-cargo linkage mechanism by JNK pathway kinases. Current Biology : Cb. 17: 1313-7. PMID 17658258 DOI: 10.1016/J.Cub.2007.06.062  0.768
2007 Saunders AM, Powers J, Strome S, Saxton WM. Kinesin-5 acts as a brake in anaphase spindle elongation. Current Biology : Cb. 17: R453-4. PMID 17580072 DOI: 10.1016/J.Cub.2007.05.001  0.5
2006 Pilling AD, Horiuchi D, Lively CM, Saxton WM. Kinesin-1 and Dynein are the primary motors for fast transport of mitochondria in Drosophila motor axons. Molecular Biology of the Cell. 17: 2057-68. PMID 16467387 DOI: 10.1091/Mbc.E05-06-0526  0.777
2005 Horiuchi D, Barkus RV, Pilling AD, Gassman A, Saxton WM. APLIP1, a kinesin binding JIP-1/JNK scaffold protein, influences the axonal transport of both vesicles and mitochondria in Drosophila. Current Biology : Cb. 15: 2137-41. PMID 16332540 DOI: 10.1016/J.Cub.2005.10.047  0.701
2005 Hollenbeck PJ, Saxton WM. The axonal transport of mitochondria. Journal of Cell Science. 118: 5411-9. PMID 16306220 DOI: 10.1242/jcs.02745  0.568
2005 Serbus LR, Cha BJ, Theurkauf WE, Saxton WM. Dynein and the actin cytoskeleton control kinesin-driven cytoplasmic streaming in Drosophila oocytes. Development (Cambridge, England). 132: 3743-52. PMID 16077093 DOI: 10.1242/Dev.01956  0.793
2005 Martin M, Ahern-Djamali SM, Hoffmann FM, Saxton WM. Abl tyrosine kinase and its substrate Ena/VASP have functional interactions with kinesin-1. Molecular Biology of the Cell. 16: 4225-30. PMID 15975902 DOI: 10.1091/Mbc.E05-02-0116  0.68
2005 Schmidt DJ, Rose DJ, Saxton WM, Strome S. Functional analysis of cytoplasmic dynein heavy chain in Caenorhabditis elegans with fast-acting temperature-sensitive mutations. Molecular Biology of the Cell. 16: 1200-12. PMID 15616192 DOI: 10.1091/Mbc.E04-06-0523  0.437
2004 Powers J, Rose DJ, Saunders A, Dunkelbarger S, Strome S, Saxton WM. Loss of KLP-19 polar ejection force causes misorientation and missegregation of holocentric chromosomes. The Journal of Cell Biology. 166: 991-1001. PMID 15452142 DOI: 10.1083/Jcb.200403036  0.368
2004 Klumpp LM, Brendza KM, Gatial JE, Hoenger A, Saxton WM, Gilbert SP. Microtubule-kinesin interface mutants reveal a site critical for communication. Biochemistry. 43: 2792-803. PMID 15005614 DOI: 10.1021/Bi035830E  0.574
2003 Segbert C, Barkus R, Powers J, Strome S, Saxton WM, Bossinger O. KLP-18, a Klp2 kinesin, is required for assembly of acentrosomal meiotic spindles in Caenorhabditis elegans. Molecular Biology of the Cell. 14: 4458-69. PMID 12937278 DOI: 10.1091/Mbc.E03-05-0283  0.739
2002 Brendza RP, Serbus LR, Saxton WM, Duffy JB. Posterior localization of dynein and dorsal-ventral axis formation depend on kinesin in Drosophila oocytes Current Biology. 12: 1541-1545. PMID 12225672 DOI: 10.1016/S0960-9822(02)01108-9  0.789
2001 Saxton WM. Microtubules, motors, and mRNA localization mechanisms: Watching fluorescent messages move Cell. 107: 707-710. PMID 11747806 DOI: 10.1016/S0092-8674(01)00602-X  0.384
2001 Yager J, Richards S, Hekmat-Scafe DS, Hurd DD, Sundaresan V, Caprette DR, Saxton WM, Carlson JR, Stern M. Control of Drosophila perineurial glial growth by interacting neurotransmitter-mediated signaling pathways. Proceedings of the National Academy of Sciences of the United States of America. 98: 10445-50. PMID 11517334 DOI: 10.1073/Pnas.191107698  0.323
2001 Strome S, Powers J, Dunn M, Reese K, Malone CJ, White J, Seydoux G, Saxton W. Spindle dynamics and the role of gamma-tubulin in early Caenorhabditis elegans embryos. Molecular Biology of the Cell. 12: 1751-64. PMID 11408582 DOI: 10.1091/Mbc.12.6.1751  0.417
2000 Brendza RP, Serbus LR, Duffy JB, Saxton WM. A function for kinesin I in the posterior transport of oskar mRNA and staufen protein Science. 289: 2120-2122. PMID 11000113 DOI: 10.1126/Science.289.5487.2120  0.772
2000 Brendza KM, Sontag CA, Saxton WM, Gilbert SP. A kinesin mutation that uncouples motor domains and desensitizes the γ-phosphate sensor Journal of Biological Chemistry. 275: 22187-22195. PMID 10767290 DOI: 10.1074/Jbc.M001124200  0.439
2000 Brendza RP, Sheehan KB, Turner FR, Saxton WM. Clonal tests of conventional kinesin function during cell proliferation and differentiation. Molecular Biology of the Cell. 11: 1329-43. PMID 10749933 DOI: 10.1091/Mbc.11.4.1329  0.534
1999 Martin MAE, Hurd DD, Saxton WM. Kinesins in the nervous system Cellular and Molecular Life Sciences. 56: 200-216. PMID 11212348 DOI: 10.1007/S000180050422  0.629
1999 Martin M, Iyadurai SJ, Gassman A, Gindhart JG, Hays TS, Saxton WM. Cytoplasmic dynein, the dynactin complex, and kinesin are interdependent and essential for fast axonal transport. Molecular Biology of the Cell. 10: 3717-28. PMID 10564267 DOI: 10.1091/Mbc.10.11.3717  0.673
1999 Brendza KM, Rese DJ, Gilbert SP, Saxton WM. Lethal kinesin mutations reveal amino acids important for ATPase activation and structural coupling Journal of Biological Chemistry. 274: 31506-31514. PMID 10531353 DOI: 10.1074/Jbc.274.44.31506  0.361
1999 Saxton WM. Intracellular motility: A special delivery service Current Biology. 9. PMID 10226021 DOI: 10.1016/S0960-9822(99)80182-1  0.403
1998 Powers J, Bossinger O, Rose D, Strome S, Saxton W. A nematode kinesin required for cleavage furrow advancement Current Biology. 8: 1133-1136. PMID 9778533 DOI: 10.1016/S0960-9822(98)70470-1  0.467
1996 Kashina AS, Scholey JM, Leszyk JD, Saxton WM. An essential bipolar mitotic motor Nature. 384: 225. PMID 8918872 DOI: 10.1038/384225A0  0.446
1996 Kurd DD, Saxton WM. Kinesin mutations cause motor neuron disease phenotypes by disrupting fast axonal transport in Drosophila Genetics. 144: 1075-1085. PMID 8913751  0.592
1996 Hurd DD, Stern M, Saxton WM. Mutation of the axonal transport motor kinesin enhances paralytic and suppresses Shaker in Drosophila Genetics. 142: 195-204. PMID 8770597  0.343
1996 Kashina AS, Baskin RJ, Cole DG, Wedaman KP, Saxton WM, Scholey JM. A bipolar kinesin Nature. 379: 270-272. PMID 8538794 DOI: 10.1038/379270A0  0.543
1994 Saxton WM. Isolation and analysis of microtubule motor proteins Methods in Cell Biology. 44: 279-288. PMID 7707957 DOI: 10.1016/S0091-679X(08)60919-X  0.465
1993 Cohn SA, Saxton WM, Lye RJ, Scholey JM. Analyzing microtubule motors in real time. Methods in Cell Biology. 39: 75-88. PMID 8246807 DOI: 10.1016/S0091-679X(08)60162-4  0.328
1992 Gho M, McDonald K, Ganetzky B, Saxton WM. Effects of kinesin mutations on neuronal functions. Science (New York, N.Y.). 258: 313-6. PMID 1384131  0.494
1991 Saxton WM, Hicks J, Goldstein LS, Raff EC. Kinesin heavy chain is essential for viability and neuromuscular functions in Drosophila, but mutants show no defects in mitosis. Cell. 64: 1093-102. PMID 1825937 DOI: 10.1016/0092-8674(91)90264-Y  0.58
1990 Yang JT, Saxton WM, Stewart RJ, Raff EC, Goldstein LS. Evidence that the head of kinesin is sufficient for force generation and motility in vitro. Science (New York, N.Y.). 249: 42-7. PMID 2142332 DOI: 10.1126/Science.2142332  0.418
1988 Saxton WM, Porter ME, Cohn SA, Scholey JM, Raff EC, McIntosh JR. Drosophila kinesin: characterization of microtubule motility and ATPase. Proceedings of the National Academy of Sciences of the United States of America. 85: 1109-13. PMID 2963338 DOI: 10.1073/Pnas.85.4.1109  0.435
1984 Saxton WM, Stemple DL, Leslie RJ, Salmon ED, Zavortink M, McIntosh JR. Tubulin dynamics in cultured mammalian cells Journal of Cell Biology. 99: 2175-2186. PMID 6501419 DOI: 10.1083/Jcb.99.6.2175  0.347
1984 Salmon ED, Leslie RJ, Saxton WM, Karow ML, McIntosh JR. Spindle microtubule dynamics in sea urchin embryos: analysis using a fluorescein-labeled tubulin and measurements of fluorescence redistribution after laser photobleaching. The Journal of Cell Biology. 99: 2165-74. PMID 6501418 DOI: 10.1083/Jcb.99.6.2165  0.396
1984 Leslie RJ, Saxton WM, Mitchison TJ, Neighbors B, Salmon ED, McIntosh JR. Assembly properties of fluorescein-labeled tubulin in vitro before and after fluorescence bleaching Journal of Cell Biology. 99: 2146-2156. PMID 6438113 DOI: 10.1083/Jcb.99.6.2146  0.355
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