cached image

Benjamin Blencowe, Ph.D. - Publications

Affiliations: 
Molecular Genetics University of Toronto, Toronto, ON, Canada 
Area:
mRNA splicing
Website:
http://www.utoronto.ca/intron/blencowe.html

125 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Aynaud MM, Hernandez JJ, Barutcu S, Braunschweig U, Chan K, Pearson JD, Trcka D, Prosser SL, Kim J, Barrios-Rodiles M, Jen M, Song S, Shen J, Bruce C, Hazlett B, ... ... Blencowe BJ, et al. A multiplexed, next generation sequencing platform for high-throughput detection of SARS-CoV-2. Nature Communications. 12: 1405. PMID 33658502 DOI: 10.1038/s41467-021-21653-y  0.56
2016 Rodrigues DC, Kim DS, Yang G, Zaslavsky K, Ha KC, Mok RS, Ross PJ, Zhao M, Piekna A, Wei W, Blencowe BJ, Morris Q, Ellis J. MECP2 Is Post-transcriptionally Regulated during Human Neurodevelopment by Combinatorial Action of RNA-Binding Proteins and miRNAs. Cell Reports. 17: 720-734. PMID 27732849 DOI: 10.1016/j.celrep.2016.09.049  0.56
2016 Tsalikis J, Pan Q, Tattoli I, Maisonneuve C, Blencowe BJ, Philpott DJ, Girardin SE. The transcriptional and splicing landscape of intestinal organoids undergoing nutrient starvation or endoplasmic reticulum stress. Bmc Genomics. 17: 680. PMID 27561422 DOI: 10.1186/s12864-016-2999-1  0.56
2016 Ennajdaoui H, Howard JM, Sterne-Weiler T, Jahanbani F, Coyne DJ, Uren PJ, Dargyte M, Katzman S, Draper JM, Wallace A, Cazarez O, Burns SC, Qiao M, Hinck L, Smith AD, ... ... Blencowe BJ, et al. IGF2BP3 Modulates the Interaction of Invasion-Associated Transcripts with RISC. Cell Reports. PMID 27210763 DOI: 10.1016/j.celrep.2016.04.083  0.56
2015 Yanling Zhao D, Gish G, Braunschweig U, Li Y, Ni Z, Schmitges FW, Zhong G, Liu K, Li W, Moffat J, Vedadi M, Min J, Pawson TJ, Blencowe BJ, Greenblatt JF. SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination. Nature. PMID 26700805 DOI: 10.1038/nature16469  0.56
2015 Merico D, Roifman M, Braunschweig U, Yuen RK, Alexandrova R, Bates A, Reid B, Nalpathamkalam T, Wang Z, Thiruvahindrapuram B, Gray P, Kakakios A, Peake J, Hogarth S, Manson D, ... ... Blencowe BJ, et al. Compound heterozygous mutations in the noncoding RNU4ATAC cause Roifman Syndrome by disrupting minor intron splicing. Nature Communications. 6: 8718. PMID 26522830 DOI: 10.1038/ncomms9718  0.56
2015 Giampietro C, Deflorian G, Gallo S, Di Matteo A, Pradella D, Bonomi S, Belloni E, Nyqvist D, Quaranta V, Confalonieri S, Bertalot G, Orsenigo F, Pisati F, Ferrero E, Biamonti G, ... ... Blencowe BJ, et al. The alternative splicing factor Nova2 regulates vascular development and lumen formation. Nature Communications. 6: 8479. PMID 26446569 DOI: 10.1038/ncomms9479  0.56
2015 Bagherie-Lachidan M, Reginensi A, Zaveri HP, Scott DA, Helmbacher F, McNeill H. Stromal Fat4 acts non-autonomously with Dachsous1/2 to restrict the nephron progenitor pool. Development (Cambridge, England). PMID 26116661 DOI: 10.1242/dev.122648  0.56
2015 Hirsch CL, Coban Akdemir Z, Wang L, Jayakumaran G, Trcka D, Weiss A, Hernandez JJ, Pan Q, Han H, Xu X, Xia Z, Salinger AP, Wilson M, Vizeacoumar F, Datti A, ... ... Blencowe BJ, et al. Myc and SAGA rewire an alternative splicing network during early somatic cell reprogramming. Genes & Development. 29: 803-16. PMID 25877919 DOI: 10.1101/gad.255109.114  0.56
2015 Quesnel-Vallières M, Irimia M, Cordes SP, Blencowe BJ. Essential roles for the splicing regulator nSR100/SRRM4 during nervous system development. Genes & Development. 29: 746-59. PMID 25838543 DOI: 10.1101/gad.256115.114  0.56
2015 Blencowe BJ. Reflections for the 20th anniversary issue of RNA journal. Rna (New York, N.Y.). 21: 573-5. PMID 25780144 DOI: 10.1261/rna.051003.115  0.56
2015 Xiong HY, Alipanahi B, Lee LJ, Bretschneider H, Merico D, Yuen RK, Hua Y, Gueroussov S, Najafabadi HS, Hughes TR, Morris Q, Barash Y, Krainer AR, Jojic N, Scherer SW, ... Blencowe BJ, et al. RNA splicing. The human splicing code reveals new insights into the genetic determinants of disease. Science (New York, N.Y.). 347: 1254806. PMID 25525159 DOI: 10.1126/science.1254806  0.56
2015 Gueroussov S, Gonatopoulos-Pournatzis T, Irimia M, Raj B, Lin ZY, Gingras AC, Blencowe BJ. An alternative splicing event amplifies evolutionary differences between vertebrates Science. 349: 868-873. DOI: 10.1126/science.aaa8381  0.56
2015 Raj B, Blencowe BJ. Alternative Splicing in the Mammalian Nervous System: Recent Insights into Mechanisms and Functional Roles Neuron. 87: 14-27. DOI: 10.1016/j.neuron.2015.05.004  0.56
2014 Irimia M, Weatheritt RJ, Ellis JD, Parikshak NN, Gonatopoulos-Pournatzis T, Babor M, Quesnel-Vallières M, Tapial J, Raj B, O'Hanlon D, Barrios-Rodiles M, Sternberg MJ, Cordes SP, Roth FP, Wrana JL, ... ... Blencowe BJ, et al. A highly conserved program of neuronal microexons is misregulated in autistic brains. Cell. 159: 1511-23. PMID 25525873 DOI: 10.1016/j.cell.2014.11.035  0.56
2014 Braunschweig U, Barbosa-Morais NL, Pan Q, Nachman EN, Alipanahi B, Gonatopoulos-Pournatzis T, Frey B, Irimia M, Blencowe BJ. Widespread intron retention in mammals functionally tunes transcriptomes. Genome Research. 24: 1774-86. PMID 25258385 DOI: 10.1101/gr.177790.114  0.56
2014 Raj B, Irimia M, Braunschweig U, Sterne-Weiler T, O'Hanlon D, Lin ZY, Chen GI, Easton LE, Ule J, Gingras AC, Eyras E, Blencowe BJ. A global regulatory mechanism for activating an exon network required for neurogenesis. Molecular Cell. 56: 90-103. PMID 25219497 DOI: 10.1016/j.molcel.2014.08.011  0.56
2014 Liu Y, Noon AP, Aguiar Cabeza E, Shen J, Kuk C, Ilczynski C, Ni R, Sukhu B, Chan K, Barbosa-Morais NL, Hermanns T, Blencowe BJ, Azad A, van der Kwast TH, Catto JW, et al. Next-generation RNA sequencing of archival formalin-fixed paraffin-embedded urothelial bladder cancer. European Urology. 66: 982-6. PMID 25199720 DOI: 10.1016/j.eururo.2014.07.045  0.56
2014 Cutz JC, Craddock KJ, Torlakovic E, Brandao G, Carter RF, Bigras G, Deschenes J, Izevbaye I, Xu Z, Greer W, Yatabe Y, Ionescu D, Karsan A, Jung S, Fraser RS, ... ... Blencowe B, et al. Canadian anaplastic lymphoma kinase study: a model for multicenter standardization and optimization of ALK testing in lung cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 9: 1255-63. PMID 25122422 DOI: 10.1097/JTO.0000000000000239  0.56
2014 Mansouri S, Pan Q, Blencowe BJ, Claycomb JM, Frappier L. Epstein-Barr virus EBNA1 protein regulates viral latency through effects on let-7 microRNA and dicer. Journal of Virology. 88: 11166-77. PMID 25031339 DOI: 10.1128/JVI.01785-14  0.56
2014 Uddin M, Tammimies K, Pellecchia G, Alipanahi B, Hu P, Wang Z, Pinto D, Lau L, Nalpathamkalam T, Marshall CR, Blencowe BJ, Frey BJ, Merico D, Yuen RK, Scherer SW. Brain-expressed exons under purifying selection are enriched for de novo mutations in autism spectrum disorder. Nature Genetics. 46: 742-7. PMID 24859339 DOI: 10.1038/ng.2980  0.56
2014 Katsani KR, Irimia M, Karapiperis C, Scouras ZG, Blencowe BJ, Promponas VJ, Ouzounis CA. Functional genomics evidence unearths new moonlighting roles of outer ring coat nucleoporins. Scientific Reports. 4: 4655. PMID 24722254 DOI: 10.1038/srep04655  0.56
2013 Sebé-Pedrós A, Irimia M, Del Campo J, Parra-Acero H, Russ C, Nusbaum C, Blencowe BJ, Ruiz-Trillo I. Regulated aggregative multicellularity in a close unicellular relative of metazoa. Elife. 2: e01287. PMID 24368732 DOI: 10.7554/eLife.01287  0.56
2013 Ray D, Kazan H, Cook KB, Weirauch MT, Najafabadi HS, Li X, Gueroussov S, Albu M, Zheng H, Yang A, Na H, Irimia M, Matzat LH, Dale RK, Smith SA, ... ... Blencowe BJ, et al. A compendium of RNA-binding motifs for decoding gene regulation. Nature. 499: 172-7. PMID 23846655 DOI: 10.1038/nature12311  0.56
2013 Han H, Irimia M, Ross PJ, Sung HK, Alipanahi B, David L, Golipour A, Gabut M, Michael IP, Nachman EN, Wang E, Trcka D, Thompson T, O'Hanlon D, Slobodeniuc V, ... ... Blencowe BJ, et al. MBNL proteins repress ES-cell-specific alternative splicing and reprogramming. Nature. 498: 241-5. PMID 23739326 DOI: 10.1038/nature12270  0.56
2013 Colak R, Kim T, Michaut M, Sun M, Irimia M, Bellay J, Myers CL, Blencowe BJ, Kim PM. Distinct types of disorder in the human proteome: functional implications for alternative splicing. Plos Computational Biology. 9: e1003030. PMID 23633940 DOI: 10.1371/journal.pcbi.1003030  0.56
2013 Braunschweig U, Gueroussov S, Plocik AM, Graveley BR, Blencowe BJ. Dynamic integration of splicing within gene regulatory pathways. Cell. 152: 1252-69. PMID 23498935 DOI: 10.1016/j.cell.2013.02.034  0.56
2013 Ward MC, Wilson MD, Barbosa-Morais NL, Schmidt D, Stark R, Pan Q, Schwalie PC, Menon S, Lukk M, Watt S, Thybert D, Kutter C, Kirschner K, Flicek P, Blencowe BJ, et al. Latent regulatory potential of human-specific repetitive elements. Molecular Cell. 49: 262-72. PMID 23246434 DOI: 10.1016/j.molcel.2012.11.013  0.56
2012 Barbosa-Morais NL, Irimia M, Pan Q, Xiong HY, Gueroussov S, Lee LJ, Slobodeniuc V, Kutter C, Watt S, Colak R, Kim T, Misquitta-Ali CM, Wilson MD, Kim PM, Odom DT, ... ... Blencowe BJ, et al. The evolutionary landscape of alternative splicing in vertebrate species. Science (New York, N.Y.). 338: 1587-93. PMID 23258890 DOI: 10.1126/science.1230612  0.56
2012 Khare T, Pai S, Koncevicius K, Pal M, Kriukiene E, Liutkeviciute Z, Irimia M, Jia P, Ptak C, Xia M, Tice R, Tochigi M, Moréra S, Nazarians A, Belsham D, ... ... Blencowe BJ, et al. 5-hmC in the brain is abundant in synaptic genes and shows differences at the exon-intron boundary. Nature Structural & Molecular Biology. 19: 1037-43. PMID 22961382 DOI: 10.1038/nsmb.2372  0.56
2012 Blencowe BJ. An exon-centric perspective. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 90: 603-12. PMID 22779775 DOI: 10.1139/o2012-019  0.56
2012 Ellis JD, Barrios-Rodiles M, Colak R, Irimia M, Kim T, Calarco JA, Wang X, Pan Q, O'Hanlon D, Kim PM, Wrana JL, Blencowe BJ. Tissue-specific alternative splicing remodels protein-protein interaction networks. Molecular Cell. 46: 884-92. PMID 22749401 DOI: 10.1016/j.molcel.2012.05.037  0.56
2012 Labbé RM, Irimia M, Currie KW, Lin A, Zhu SJ, Brown DD, Ross EJ, Voisin V, Bader GD, Blencowe BJ, Pearson BJ. A comparative transcriptomic analysis reveals conserved features of stem cell pluripotency in planarians and mammals. Stem Cells (Dayton, Ohio). 30: 1734-45. PMID 22696458 DOI: 10.1002/stem.1144  0.56
2012 Irimia M, Blencowe BJ. Alternative splicing: decoding an expansive regulatory layer. Current Opinion in Cell Biology. 24: 323-32. PMID 22465326 DOI: 10.1016/j.ceb.2012.03.005  0.56
2012 Martinez NM, Pan Q, Cole BS, Yarosh CA, Babcock GA, Heyd F, Zhu W, Ajith S, Blencowe BJ, Lynch KW. Alternative splicing networks regulated by signaling in human T cells. Rna (New York, N.Y.). 18: 1029-40. PMID 22454538 DOI: 10.1261/rna.032243.112  0.56
2011 Lahiry P, Lee LJ, Frey BJ, Rupar CA, Siu VM, Blencowe BJ, Hegele RA. Transcriptional profiling of endocrine cerebro-osteodysplasia using microarray and next-generation sequencing. Plos One. 6: e25400. PMID 21980446 DOI: 10.1371/journal.pone.0025400  0.56
2011 Han H, Nutiu R, Moffat J, Blencowe BJ. SnapShot: High-throughput sequencing applications. Cell. 146: 1044, 1044.e1-2. PMID 21925324 DOI: 10.1016/j.cell.2011.09.002  0.56
2011 Gabut M, Samavarchi-Tehrani P, Wang X, Slobodeniuc V, O'Hanlon D, Sung HK, Alvarez M, Talukder S, Pan Q, Mazzoni EO, Nedelec S, Wichterle H, Woltjen K, Hughes TR, Zandstra PW, ... ... Blencowe BJ, et al. An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming. Cell. 147: 132-46. PMID 21924763 DOI: 10.1016/j.cell.2011.08.023  0.56
2011 Raj B, O'Hanlon D, Vessey JP, Pan Q, Ray D, Buckley NJ, Miller FD, Blencowe BJ. Cross-regulation between an alternative splicing activator and a transcription repressor controls neurogenesis. Molecular Cell. 43: 843-50. PMID 21884984 DOI: 10.1016/j.molcel.2011.08.014  0.56
2011 Voineagu I, Wang X, Johnston P, Lowe JK, Tian Y, Horvath S, Mill J, Cantor RM, Blencowe BJ, Geschwind DH. Transcriptomic analysis of autistic brain reveals convergent molecular pathology. Nature. 474: 380-4. PMID 21614001 DOI: 10.1038/nature10110  0.56
2011 Calarco JA, Zhen M, Blencowe BJ. Networking in a global world: establishing functional connections between neural splicing regulators and their target transcripts. Rna (New York, N.Y.). 17: 775-91. PMID 21415141 DOI: 10.1261/rna.2603911  0.56
2011 Saltzman AL, Pan Q, Blencowe BJ. Regulation of alternative splicing by the core spliceosomal machinery. Genes & Development. 25: 373-84. PMID 21325135 DOI: 10.1101/gad.2004811  0.56
2011 Ramani AK, Calarco JA, Pan Q, Mavandadi S, Wang Y, Nelson AC, Lee LJ, Morris Q, Blencowe BJ, Zhen M, Fraser AG. Genome-wide analysis of alternative splicing in Caenorhabditis elegans. Genome Research. 21: 342-8. PMID 21177968 DOI: 10.1101/gr.114645.110  0.56
2011 Ip JY, Schmidt D, Pan Q, Ramani AK, Fraser AG, Odom DT, Blencowe BJ. Global impact of RNA polymerase II elongation inhibition on alternative splicing regulation. Genome Research. 21: 390-401. PMID 21163941 DOI: 10.1101/gr.111070.110  0.56
2011 Misquitta-Ali CM, Cheng E, O'Hanlon D, Liu N, McGlade CJ, Tsao MS, Blencowe BJ. Global profiling and molecular characterization of alternative splicing events misregulated in lung cancer. Molecular and Cellular Biology. 31: 138-50. PMID 21041478 DOI: 10.1128/MCB.00709-10  0.56
2011 van Bakel H, Nislow C, Blencowe BJ, Hughes TR. Response to "The reality of pervasive transcription" Plos Biology. 9. DOI: 10.1371/journal.pbio.1001102  0.56
2010 Tripathi V, Ellis JD, Shen Z, Song DY, Pan Q, Watt AT, Freier SM, Bennett CF, Sharma A, Bubulya PA, Blencowe BJ, Prasanth SG, Prasanth KV. The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation. Molecular Cell. 39: 925-38. PMID 20797886 DOI: 10.1016/j.molcel.2010.08.011  0.56
2010 McIlwain DR, Pan Q, Reilly PT, Elia AJ, McCracken S, Wakeham AC, Itie-Youten A, Blencowe BJ, Mak TW. Smg1 is required for embryogenesis and regulates diverse genes via alternative splicing coupled to nonsense-mediated mRNA decay. Proceedings of the National Academy of Sciences of the United States of America. 107: 12186-91. PMID 20566848 DOI: 10.1073/pnas.1007336107  0.56
2010 Barash Y, Blencowe BJ, Frey BJ. Model-based detection of alternative splicing signals. Bioinformatics (Oxford, England). 26: i325-33. PMID 20529924 DOI: 10.1093/bioinformatics/btq200  0.56
2010 van Bakel H, Nislow C, Blencowe BJ, Hughes TR. Most "dark matter" transcripts are associated with known genes. Plos Biology. 8: e1000371. PMID 20502517 DOI: 10.1371/journal.pbio.1000371  0.56
2010 Barash Y, Calarco JA, Gao W, Pan Q, Wang X, Shai O, Blencowe BJ, Frey BJ. Deciphering the splicing code. Nature. 465: 53-9. PMID 20445623 DOI: 10.1038/nature09000  0.56
2010 Luco RF, Pan Q, Tominaga K, Blencowe BJ, Pereira-Smith OM, Misteli T. Regulation of alternative splicing by histone modifications. Science (New York, N.Y.). 327: 996-1000. PMID 20133523 DOI: 10.1126/science.1184208  0.56
2009 Khanna M, Van Bakel H, Tang X, Calarco JA, Babak T, Guo G, Emili A, Greenblatt JF, Hughes TR, Krogan NJ, Blencowe BJ. A systematic characterization of Cwc21, the yeast ortholog of the human spliceosomal protein SRm300. Rna (New York, N.Y.). 15: 2174-85. PMID 19789211 DOI: 10.1261/rna.1790509  0.56
2009 Kornblihtt AR, Schor IE, Allo M, Blencowe BJ. When chromatin meets splicing. Nature Structural & Molecular Biology. 16: 902-3. PMID 19739285 DOI: 10.1038/nsmb0909-902  0.56
2009 Calarco JA, Superina S, O'Hanlon D, Gabut M, Raj B, Pan Q, Skalska U, Clarke L, Gelinas D, van der Kooy D, Zhen M, Ciruna B, Blencowe BJ. Regulation of vertebrate nervous system alternative splicing and development by an SR-related protein. Cell. 138: 898-910. PMID 19737518 DOI: 10.1016/j.cell.2009.06.012  0.56
2009 Ray D, Kazan H, Chan ET, Peña Castillo L, Chaudhry S, Talukder S, Blencowe BJ, Morris Q, Hughes TR. Rapid and systematic analysis of the RNA recognition specificities of RNA-binding proteins. Nature Biotechnology. 27: 667-70. PMID 19561594 DOI: 10.1038/nbt.1550  0.56
2009 Blencowe BJ, Ahmad S, Lee LJ. Current-generation high-throughput sequencing: deepening insights into mammalian transcriptomes. Genes & Development. 23: 1379-86. PMID 19528315 DOI: 10.1101/gad.1788009  0.56
2009 Blencowe B, Brenner S, Hughes T, Morris Q. Post-transcriptional gene regulation: RNA-protein interactions, RNA processing, mRNA stability and localization. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 545-8. PMID 19209730  0.56
2008 Pan Q, Shai O, Lee LJ, Frey BJ, Blencowe BJ. Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing. Nature Genetics. 40: 1413-5. PMID 18978789 DOI: 10.1038/ng.259  0.56
2008 Aznarez I, Barash Y, Shai O, He D, Zielenski J, Tsui LC, Parkinson J, Frey BJ, Rommens JM, Blencowe BJ. A systematic analysis of intronic sequences downstream of 5' splice sites reveals a widespread role for U-rich motifs and TIA1/TIAL1 proteins in alternative splicing regulation. Genome Research. 18: 1247-58. PMID 18456862 DOI: 10.1101/gr.073155.107  0.56
2008 Saltzman AL, Kim YK, Pan Q, Fagnani MM, Maquat LE, Blencowe BJ. Regulation of multiple core spliceosomal proteins by alternative splicing-coupled nonsense-mediated mRNA decay. Molecular and Cellular Biology. 28: 4320-30. PMID 18443041 DOI: 10.1128/MCB.00361-08  0.56
2008 Gabut M, Chaudhry S, Blencowe BJ. SnapShot: The splicing regulatory machinery. Cell. 133: 192.e1. PMID 18394998 DOI: 10.1016/j.cell.2008.03.010  0.56
2007 Calarco JA, Saltzman AL, Ip JY, Blencowe BJ. Technologies for the global discovery and analysis of alternative splicing. Advances in Experimental Medicine and Biology. 623: 64-84. PMID 18380341  0.56
2007 Huang JC, Babak T, Corson TW, Chua G, Khan S, Gallie BL, Hughes TR, Blencowe BJ, Frey BJ, Morris QD. Using expression profiling data to identify human microRNA targets. Nature Methods. 4: 1045-9. PMID 18026111 DOI: 10.1038/nmeth1130  0.56
2007 Calarco JA, Xing Y, Cáceres M, Calarco JP, Xiao X, Pan Q, Lee C, Preuss TM, Blencowe BJ. Global analysis of alternative splicing differences between humans and chimpanzees. Genes & Development. 21: 2963-75. PMID 17978102 DOI: 10.1101/gad.1606907  0.56
2007 Fagnani M, Barash Y, Ip JY, Misquitta C, Pan Q, Saltzman AL, Shai O, Lee L, Rozenhek A, Mohammad N, Willaime-Morawek S, Babak T, Zhang W, Hughes TR, van der Kooy D, ... ... Blencowe BJ, et al. Functional coordination of alternative splicing in the mammalian central nervous system. Genome Biology. 8: R108. PMID 17565696 DOI: 10.1186/gb-2007-8-6-r108  0.56
2007 Fortes P, Longman D, McCracken S, Ip JY, Poot R, Mattaj IW, Cáceres JF, Blencowe BJ. Identification and characterization of RED120: a conserved PWI domain protein with links to splicing and 3'-end formation. Febs Letters. 581: 3087-97. PMID 17560998 DOI: 10.1016/j.febslet.2007.05.066  0.56
2007 Blencowe BJ, Khanna M. Molecular biology: RNA in control. Nature. 447: 391-3. PMID 17522667 DOI: 10.1038/447391a  0.56
2007 Aznarez I, Zielenski J, Rommens JM, Blencowe BJ, Tsui LC. Exon skipping through the creation of a putative exonic splicing silencer as a consequence of the cystic fibrosis mutation R553X. Journal of Medical Genetics. 44: 341-6. PMID 17475917 DOI: 10.1136/jmg.2006.045880  0.56
2007 Ip JY, Tong A, Pan Q, Topp JD, Blencowe BJ, Lynch KW. Global analysis of alternative splicing during T-cell activation. Rna (New York, N.Y.). 13: 563-72. PMID 17307815 DOI: 10.1261/rna.457207  0.56
2007 Babak T, Blencowe BJ, Hughes TR. Considerations in the identification of functional RNA structural elements in genomic alignments. Bmc Bioinformatics. 8: 33. PMID 17263882 DOI: 10.1186/1471-2105-8-33  0.56
2006 Ule J, Stefani G, Mele A, Ruggiu M, Wang X, Taneri B, Gaasterland T, Blencowe BJ, Darnell RB. An RNA map predicting Nova-dependent splicing regulation. Nature. 444: 580-6. PMID 17065982 DOI: 10.1038/nature05304  0.56
2006 Hughes TR, Hiley SL, Saltzman AL, Babak T, Blencowe BJ. Microarray analysis of RNA processing and modification. Methods in Enzymology. 410: 300-16. PMID 16938557 DOI: 10.1016/S0076-6879(06)10014-2  0.56
2006 Blencowe BJ. Alternative splicing: new insights from global analyses. Cell. 126: 37-47. PMID 16839875 DOI: 10.1016/j.cell.2006.06.023  0.56
2006 Pan Q, Saltzman AL, Kim YK, Misquitta C, Shai O, Maquat LE, Frey BJ, Blencowe BJ. Quantitative microarray profiling provides evidence against widespread coupling of alternative splicing with nonsense-mediated mRNA decay to control gene expression. Genes & Development. 20: 153-8. PMID 16418482 DOI: 10.1101/gad.1382806  0.56
2006 Shai O, Morris QD, Blencowe BJ, Frey BJ. Inferring global levels of alternative splicing isoforms using a generative model of microarray data. Bioinformatics (Oxford, England). 22: 606-13. PMID 16403798 DOI: 10.1093/bioinformatics/btk028  0.56
2006 López-Bigas N, Blencowe BJ, Ouzounis CA. Highly consistent patterns for inherited human diseases at the molecular level. Bioinformatics (Oxford, England). 22: 269-77. PMID 16287936 DOI: 10.1093/bioinformatics/bti781  0.56
2005 McCracken S, Longman D, Marcon E, Moens P, Downey M, Nickerson JA, Jessberger R, Wilde A, Caceres JF, Emili A, Blencowe BJ. Proteomic analysis of SRm160-containing complexes reveals a conserved association with cohesin. The Journal of Biological Chemistry. 280: 42227-36. PMID 16159877 DOI: 10.1074/jbc.M507410200  0.56
2005 Frey BJ, Mohammad N, Morris QD, Zhang W, Robinson MD, Mnaimneh S, Chang R, Pan Q, Sat E, Rossant J, Bruneau BG, Aubin JE, Blencowe BJ, Hughes TR. Genome-wide analysis of mouse transcripts using exon microarrays and factor graphs. Nature Genetics. 37: 991-6. PMID 16127451 DOI: 10.1038/ng1630  0.56
2005 Babak T, Blencowe BJ, Hughes TR. A systematic search for new mammalian noncoding RNAs indicates little conserved intergenic transcription. Bmc Genomics. 6: 104. PMID 16083503 DOI: 10.1186/1471-2164-6-104  0.56
2005 Blencowe BJ. Splicing on the brain. Nature Genetics. 37: 796-7. PMID 16049505 DOI: 10.1038/ng0805-796  0.56
2005 Rosonina E, Ip JY, Calarco JA, Bakowski MA, Emili A, McCracken S, Tucker P, Ingles CJ, Blencowe BJ. Role for PSF in mediating transcriptional activator-dependent stimulation of pre-mRNA processing in vivo. Molecular and Cellular Biology. 25: 6734-46. PMID 16024807 DOI: 10.1128/MCB.25.15.6734-6746.2005  0.56
2005 Pan Q, Bakowski MA, Morris Q, Zhang W, Frey BJ, Hughes TR, Blencowe BJ. Alternative splicing of conserved exons is frequently species-specific in human and mouse. Trends in Genetics : Tig. 21: 73-7. PMID 15661351 DOI: 10.1016/j.tig.2004.12.004  0.56
2005 Shai O, Frey BJ, Morris QD, Pan Q, Misquitta C, Blencowe BJ. Probabilistic inference of alternative splicing events in microarray data Advances in Neural Information Processing Systems 0.56
2004 Pan Q, Shai O, Misquitta C, Zhang W, Saltzman AL, Mohammad N, Babak T, Siu H, Hughes TR, Morris QD, Frey BJ, Blencowe BJ. Revealing global regulatory features of mammalian alternative splicing using a quantitative microarray platform. Molecular Cell. 16: 929-41. PMID 15610736 DOI: 10.1016/j.molcel.2004.12.004  0.56
2004 Zhang W, Morris QD, Chang R, Shai O, Bakowski MA, Mitsakakis N, Mohammad N, Robinson MD, Zirngibl R, Somogyi E, Laurin N, Eftekharpour E, Sat E, Grigull J, Pan Q, ... ... Blencowe BJ, et al. The functional landscape of mouse gene expression. Journal of Biology. 3: 21. PMID 15588312 DOI: 10.1186/jbiol16  0.56
2004 Babak T, Zhang W, Morris Q, Blencowe BJ, Hughes TR. Probing microRNAs with microarrays: tissue specificity and functional inference. Rna (New York, N.Y.). 10: 1813-9. PMID 15496526 DOI: 10.1261/rna.7119904  0.56
2004 Lew JM, Fei YL, Aleck K, Blencowe BJ, Weksberg R, Sadowski PD. CDKN1C mutation in Wiedemann-Beckwith syndrome patients reduces RNA splicing efficiency and identifies a splicing enhancer. American Journal of Medical Genetics. Part A. 127: 268-76. PMID 15150778 DOI: 10.1002/ajmg.a.30020  0.56
2004 Custódio N, Carvalho C, Condado I, Antoniou M, Blencowe BJ, Carmo-Fonseca M. In vivo recruitment of exon junction complex proteins to transcription sites in mammalian cell nuclei. Rna (New York, N.Y.). 10: 622-33. PMID 15037772 DOI: 10.1261/rna.5258504  0.56
2004 Rosonina E, Blencowe BJ. Analysis of the requirement for RNA polymerase II CTD heptapeptide repeats in pre-mRNA splicing and 3'-end cleavage. Rna (New York, N.Y.). 10: 581-9. PMID 15037767 DOI: 10.1261/rna.5207204  0.56
2003 McCracken S, Longman D, Johnstone IL, Cáceres JF, Blencowe BJ. An evolutionarily conserved role for SRm160 in 3'-end processing that functions independently of exon junction complex formation. The Journal of Biological Chemistry. 278: 44153-60. PMID 12944400 DOI: 10.1074/jbc.M306856200  0.56
2003 Rosonina E, Bakowski MA, McCracken S, Blencowe BJ. Transcriptional activators control splicing and 3'-end cleavage levels. The Journal of Biological Chemistry. 278: 43034-40. PMID 12939267 DOI: 10.1074/jbc.M307289200  0.56
2003 Aznarez I, Chan EM, Zielenski J, Blencowe BJ, Tsui LC. Characterization of disease-associated mutations affecting an exonic splicing enhancer and two cryptic splice sites in exon 13 of the cystic fibrosis transmembrane conductance regulator gene. Human Molecular Genetics. 12: 2031-40. PMID 12913074 DOI: 10.1093/hmg/ddg215  0.56
2003 Szymczyna BR, Bowman J, McCracken S, Pineda-Lucena A, Lu Y, Cox B, Lambermon M, Graveley BR, Arrowsmith CH, Blencowe BJ. Structure and function of the PWI motif: a novel nucleic acid-binding domain that facilitates pre-mRNA processing. Genes & Development. 17: 461-75. PMID 12600940 DOI: 10.1101/gad.1060403  0.56
2003 Blencowe BJ. Splicing regulation: the cell cycle connection. Current Biology : Cb. 13: R149-51. PMID 12593819 DOI: 10.1016/S0960-9822(03)00079-4  0.56
2002 Emili A, Shales M, McCracken S, Xie W, Tucker PW, Kobayashi R, Blencowe BJ, Ingles CJ. Splicing and transcription-associated proteins PSF and p54nrb/nonO bind to the RNA polymerase II CTD. Rna (New York, N.Y.). 8: 1102-11. PMID 12358429 DOI: 10.1017/S1355838202025037  0.56
2002 Rosonina E, Blencowe BJ. Gene expression: the close coupling of transcription and splicing. Current Biology : Cb. 12: R319-21. PMID 12007432 DOI: 10.1016/S0960-9822(02)00829-1  0.56
2002 Blencowe BJ. Transcription: surprising role for an elusive small nuclear RNA. Current Biology : Cb. 12: R147-9. PMID 11864590 DOI: 10.1016/S0960-9822(02)00711-X  0.56
2002 McCracken S, Lambermon M, Blencowe BJ. SRm160 splicing coactivator promotes transcript 3'-end cleavage. Molecular and Cellular Biology. 22: 148-60. PMID 11739730 DOI: 10.1128/MCB.22.1.148-160.2002  0.56
2001 Boucher L, Ouzounis CA, Enright AJ, Blencowe BJ. A genome-wide survey of RS domain proteins. Rna (New York, N.Y.). 7: 1693-701. PMID 11780626  0.56
2001 Longman D, McGarvey T, McCracken S, Johnstone IL, Blencowe BJ, Cáceres JF. Multiple interactions between SRm160 and SR family proteins in enhancer-dependent splicing and development of C. elegans. Current Biology : Cb. 11: 1923-33. PMID 11747818 DOI: 10.1016/S0960-9822(01)00589-9  0.56
2001 Rodrigues JP, Rode M, Gatfield D, Blencowe BJ, Carmo-Fonseca M, Izaurralde E. REF proteins mediate the export of spliced and unspliced mRNAs from the nucleus. Proceedings of the National Academy of Sciences of the United States of America. 98: 1030-5. PMID 11158589 DOI: 10.1073/pnas.031586198  0.56
2000 McGarvey T, Rosonina E, McCracken S, Li Q, Arnaout R, Mientjes E, Nickerson JA, Awrey D, Greenblatt J, Grosveld G, Blencowe BJ. The acute myeloid leukemia-associated protein, DEK, forms a splicing-dependent interaction with exon-product complexes. The Journal of Cell Biology. 150: 309-20. PMID 10908574 DOI: 10.1083/jcb.150.2.309  0.56
2000 Blencowe BJ. Exonic splicing enhancers: mechanism of action, diversity and role in human genetic diseases. Trends in Biochemical Sciences. 25: 106-10. PMID 10694877 DOI: 10.1016/S0968-0004(00)01549-8  0.56
2000 Blencowe BJ, Baurén G, Eldridge AG, Issner R, Nickerson JA, Rosonina E, Sharp PA. The SRm160/300 splicing coactivator subunits. Rna (New York, N.Y.). 6: 111-20. PMID 10668804 DOI: 10.1017/S1355838200991982  0.56
1999 Li Y, Blencowe BJ. Distinct factor requirements for exonic splicing enhancer function and binding of U2AF to the polypyrimidine tract. The Journal of Biological Chemistry. 274: 35074-9. PMID 10574987 DOI: 10.1074/jbc.274.49.35074  0.56
1999 Blencowe BJ, Lamond AI. Purification and depletion of RNP particles by antisense affinity chromatography. Methods in Molecular Biology (Clifton, N.J.). 118: 275-87. PMID 10549530 DOI: 10.1385/1-59259-676-2:275  0.56
1999 Blencowe BJ, Bowman JA, McCracken S, Rosonina E. SR-related proteins and the processing of messenger RNA precursors. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 77: 277-91. PMID 10546891 DOI: 10.1139/bcb-77-4-277  0.56
1999 Eldridge AG, Li Y, Sharp PA, Blencowe BJ. The SRm160/300 splicing coactivator is required for exon-enhancer function. Proceedings of the National Academy of Sciences of the United States of America. 96: 6125-30. PMID 10339552 DOI: 10.1073/pnas.96.11.6125  0.56
1999 Blencowe BJ, Ouzounis CA. The PWI motif: a new protein domain in splicing factors. Trends in Biochemical Sciences. 24: 179-80. PMID 10322432 DOI: 10.1016/S0968-0004(99)01387-0  0.56
1998 Blencowe BJ, Issner R, Nickerson JA, Sharp PA. A coactivator of pre-mRNA splicing. Genes & Development. 12: 996-1009. PMID 9531537  0.56
1996 Mortillaro MJ, Blencowe BJ, Wei X, Nakayasu H, Du L, Warren SL, Sharp PA, Berezney R. A hyperphosphorylated form of the large subunit of RNA polymerase II is associated with splicing complexes and the nuclear matrix. Proceedings of the National Academy of Sciences of the United States of America. 93: 8253-7. PMID 8710856 DOI: 10.1073/pnas.93.16.8253  0.56
1995 Nickerson JA, Blencowe BJ, Penman S. The architectural organization of nuclear metabolism. International Review of Cytology. 162: 67-123. PMID 8575888  0.56
1995 Blencowe BJ, Barabino SM. Antisense affinity depletion of RNP particles. Application to spliceosomal snRNPs. Methods in Molecular Biology (Clifton, N.J.). 37: 67-76. PMID 7780522 DOI: 10.1385/0-89603-288-4:67  0.56
1995 Blencowe BJ, Issner R, Kim J, Mccaw P, Sharp PA. New proteins related to the Ser-Arg family of splicing factors. Rna (New York, N.Y.). 1: 852-65. PMID 7493330  0.56
1994 Crispino JD, Blencowe BJ, Sharp PA. Complementation by SR proteins of pre-mRNA splicing reactions depleted of U1 snRNP. Science (New York, N.Y.). 265: 1866-9. PMID 8091213  0.56
1994 Blencowe BJ, Nickerson JA, Issner R, Penman S, Sharp PA. Association of nuclear matrix antigens with exon-containing splicing complexes. The Journal of Cell Biology. 127: 593-607. PMID 7962048 DOI: 10.1083/jcb.127.3.593  0.56
1993 Blencowe BJ, Carmo-Fonseca M, Behrens SE, Lührmann R, Lamond AI. Interaction of the human autoantigen p150 with splicing snRNPs. Journal of Cell Science. 105: 685-97. PMID 8408296  0.56
1991 Ouzounis CA, Blencowe BJ. Bacterial DNA replication initiation factor priA is related to proteins belonging to the 'DEAD-box' family. Nucleic Acids Research. 19: 6953. PMID 1662369 DOI: 10.1093/nar/19.24.6953  0.56
1991 Lamm GM, Blencowe BJ, Sproat BS, Iribarren AM, Ryder U, Lamond AI. Antisense probes containing 2-aminoadenosine allow efficient depletion of U5 snRNP from HeLa splicing extracts. Nucleic Acids Research. 19: 3193-8. PMID 1648201  0.56
1990 Barabino SM, Blencowe BJ, Ryder U, Sproat BS, Lamond AI. Targeted snRNP depletion reveals an additional role for mammalian U1 snRNP in spliceosome assembly. Cell. 63: 293-302. PMID 2170025 DOI: 10.1016/0092-8674(90)90162-8  0.56
1990 Sibbald PR, Blencowe BJ. A completely conserved rat U6 snRNA pseudogene coding sequence is sandwiched between a cytochrome c retropseudogene and a LINE-like sequence. Nucleic Acids Research. 18: 1063. PMID 2156224 DOI: 10.1093/nar/18.4.1063  0.56
1990 Lamond AI, Barabino S, Blencowe BJ, Sproat B, Ryder U. Studying pre-mRNA splicing using antisense 2-OMe RNA oligonucleotides. Molecular Biology Reports. 14: 201. PMID 1694562 DOI: 10.1007/BF00360473  0.56
1989 Barabino SM, Sproat BS, Ryder U, Blencowe BJ, Lamond AI. Mapping U2 snRNP--pre-mRNA interactions using biotinylated oligonucleotides made of 2'-OMe RNA. The Embo Journal. 8: 4171-8. PMID 2531659  0.56
1989 Blencowe BJ, Sproat BS, Ryder U, Barabino S, Lamond AI. Antisense probing of the human U4/U6 snRNP with biotinylated 2'-OMe RNA oligonucleotides. Cell. 59: 531-9. PMID 2478298 DOI: 10.1016/0092-8674(89)90036-6  0.56
Show low-probability matches.