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Tom A. Rapoport, Ph.D. - Publications

Affiliations: 
Cell Biology Harvard Medical School, Boston, MA, United States 
Area:
Endoplasmic Reticulum, Secretion
Website:
http://rapoport.hms.harvard.edu/index.php/public/page/home

237/244 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Ma C, Wu X, Sun D, Park E, Catipovic MA, Rapoport TA, Gao N, Li L. Structure of the substrate-engaged SecA-SecY protein translocation machine. Nature Communications. 10: 2872. PMID 31253804 DOI: 10.1038/s41467-019-10918-2  1
2019 Romano FB, Blok NB, Rapoport TA. Peroxisome protein import recapitulated in egg extracts. The Journal of Cell Biology. PMID 30971414 DOI: 10.1083/jcb.201901152  0.96
2019 Catipovic MA, Bauer BW, Loparo JJ, Rapoport TA. Protein translocation by the SecA ATPase occurs by a power-stroke mechanism. The Embo Journal. PMID 30877095 DOI: 10.15252/embj.2018101140  0.64
2019 Wang N, Rapoport TA. Reconstituting the reticular ER network - mechanistic implications and open questions. Journal of Cell Science. 132. PMID 30670475 DOI: 10.1242/jcs.227611  0.4
2018 Wu X, Cabanos C, Rapoport TA. Structure of the post-translational protein translocation machinery of the ER membrane. Nature. PMID 30644436 DOI: 10.1038/s41586-018-0856-x  1
2018 Wang S, Powers RE, Gold VA, Rapoport TA. The ER morphology-regulating lunapark protein induces the formation of stacked bilayer discs. Life Science Alliance. 1: e201700014. PMID 30456344 DOI: 10.26508/lsa.201700014  0.96
2018 Wu X, Rapoport TA. Mechanistic insights into ER-associated protein degradation. Current Opinion in Cell Biology. 53: 22-28. PMID 29719269 DOI: 10.1016/j.ceb.2018.04.004  1
2018 Wang S, Romano FB, Rapoport TA. Endoplasmic Reticulum Network Formation withEgg Extracts. Cold Spring Harbor Protocols. PMID 29475993 DOI: 10.1101/pdb.prot097204  0.96
2018 Chen Y, Bensing BA, Seepersaud R, Mi W, Liao M, Jeffrey PD, Shajahan A, Sonon RN, Azadi P, Sullam PM, Rapoport TA. Unraveling the sequence of cytosolic reactions in the export of GspB adhesin from. The Journal of Biological Chemistry. PMID 29462788 DOI: 10.1074/jbc.RA117.000963  0.32
2017 Schoebel S, Mi W, Stein A, Ovchinnikov S, Pavlovicz R, DiMaio F, Baker D, Chambers MG, Su H, Li D, Rapoport TA, Liao M. Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3. Nature. PMID 28682307 DOI: 10.1038/nature23314  0.56
2017 Rapoport TA, Li L, Park E. Structural and Mechanistic Insights into Protein Translocation. Annual Review of Cell and Developmental Biology. PMID 28564553 DOI: 10.1146/annurev-cellbio-100616-060439  1
2017 Tripathi A, Mandon EC, Gilmore R, Rapoport TA. Two alternative binding mechanisms connect the protein translocation Sec71/Sec72 complex with heat shock proteins. The Journal of Biological Chemistry. PMID 28286332 DOI: 10.1074/jbc.M116.761122  0.4
2017 Powers RE, Wang S, Liu TY, Rapoport TA. Reconstitution of the tubular endoplasmic reticulum network with purified components. Nature. PMID 28225760 DOI: 10.1038/nature21387  0.96
2016 Wang S, Tukachinsky H, Romano FB, Rapoport TA. Cooperation of the ER-shaping proteins atlastin, lunapark, and reticulons to generate a tubular membrane network. Elife. 5. PMID 27619977 DOI: 10.7554/eLife.18605  0.96
2016 Hu J, Rapoport TA. Fusion of the endoplasmic reticulum by membrane-bound GTPases. Seminars in Cell & Developmental Biology. PMID 27269373 DOI: 10.1016/j.semcdb.2016.06.001  1
2016 Li L, Park E, Ling J, Ingram J, Ploegh H, Rapoport TA. Crystal structure of a substrate-engaged SecY protein-translocation channel. Nature. PMID 26950603 DOI: 10.1038/nature17163  1
2016 Meyer PA, Socias S, Key J, Ransey E, Tjon EC, Buschiazzo A, Lei M, Botka C, Withrow J, Neau D, Rajashankar K, Anderson KS, Baxter RH, Blacklow SC, Boggon TJ, ... ... Rapoport TA, et al. Data publication with the structural biology data grid supports live analysis. Nature Communications. 7: 10882. PMID 26947396 DOI: 10.1038/ncomms10882  1
2015 Tan D, Blok NB, Rapoport TA, Walz T. Structures of the double-ring AAA ATPase Pex1/Pex6 involved in peroxisome biogenesis. The Febs Journal. PMID 26476099 DOI: 10.1111/febs.13569  0.6
2015 Junker M, Rapoport TA. Involvement of VAT-1 in phosphatidylserine transfer from the endoplasmic reticulum to mitochondria. Traffic (Copenhagen, Denmark). PMID 26394711 DOI: 10.1111/tra.12336  1
2015 Blok NB, Tan D, Wang RY, Penczek PA, Baker D, DiMaio F, Rapoport TA, Walz T. Unique double-ring structure of the peroxisomal Pex1/Pex6 ATPase complex revealed by cryo-electron microscopy. Proceedings of the National Academy of Sciences of the United States of America. PMID 26170309 DOI: 10.1073/pnas.1500257112  1
2015 Chen Y, Bauer BW, Rapoport TA, Gumbart JC. Conformational Changes of the Clamp of the Protein Translocation ATPase SecA. Journal of Molecular Biology. 427: 2348-59. PMID 25982945 DOI: 10.1016/j.jmb.2015.05.003  1
2015 Liu TY, Bian X, Romano FB, Shemesh T, Rapoport TA, Hu J. Cis and trans interactions between atlastin molecules during membrane fusion. Proceedings of the National Academy of Sciences of the United States of America. 112: E1851-60. PMID 25825753 DOI: 10.1073/pnas.1504368112  1
2015 Junne T, Wong J, Studer C, Aust T, Bauer BW, Beibel M, Bhullar B, Bruccoleri R, Eichenberger J, Estoppey D, Hartmann N, Knapp B, Krastel P, Melin N, Oakeley EJ, ... ... Rapoport TA, et al. Decatransin, a new natural product inhibiting protein translocation at the Sec61/SecYEG translocon. Journal of Cell Science. 128: 1217-29. PMID 25616894 DOI: 10.1242/jcs.165746  1
2014 Shemesh T, Klemm RW, Romano FB, Wang S, Vaughan J, Zhuang X, Tukachinsky H, Kozlov MM, Rapoport TA. A model for the generation and interconversion of ER morphologies. Proceedings of the National Academy of Sciences of the United States of America. 111: E5243-51. PMID 25404289 DOI: 10.1073/pnas.1419997111  1
2014 Stein A, Ruggiano A, Carvalho P, Rapoport TA. Key steps in ERAD of luminal ER proteins reconstituted with purified components. Cell. 158: 1375-88. PMID 25215493 DOI: 10.1016/j.cell.2014.07.050  1
2014 Bauer BW, Shemesh T, Chen Y, Rapoport TA. A "push and slide" mechanism allows sequence-insensitive translocation of secretory proteins by the SecA ATPase. Cell. 157: 1416-29. PMID 24906156 DOI: 10.1016/j.cell.2014.03.063  1
2014 Markgraf DF, Klemm RW, Junker M, Hannibal-Bach HK, Ejsing CS, Rapoport TA. An ER protein functionally couples neutral lipid metabolism on lipid droplets to membrane lipid synthesis in the ER. Cell Reports. 6: 44-55. PMID 24373967 DOI: 10.1016/j.celrep.2013.11.046  0.64
2014 Li L, Fierer JO, Rapoport TA, Howarth M. Structural analysis and optimization of the covalent association between SpyCatcher and a peptide Tag. Journal of Molecular Biology. 426: 309-17. PMID 24161952 DOI: 10.1016/j.jmb.2013.10.021  1
2014 Park E, Ménétret JF, Gumbart JC, Ludtke SJ, Li W, Whynot A, Rapoport TA, Akey CW. Structure of the SecY channel during initiation of protein translocation. Nature. 506: 102-6. PMID 24153188 DOI: 10.1038/nature12720  1
2013 Wang S, Romano FB, Field CM, Mitchison TJ, Rapoport TA. Multiple mechanisms determine ER network morphology during the cell cycle in Xenopus egg extracts. The Journal of Cell Biology. 203: 801-14. PMID 24297752 DOI: 10.1083/jcb.201308001  1
2013 Terasaki M, Shemesh T, Kasthuri N, Klemm RW, Schalek R, Hayworth KJ, Hand AR, Yankova M, Huber G, Lichtman JW, Rapoport TA, Kozlov MM. Stacked endoplasmic reticulum sheets are connected by helicoidal membrane motifs. Cell. 154: 285-96. PMID 23870120 DOI: 10.1016/j.cell.2013.06.031  1
2013 Klemm RW, Norton JP, Cole RA, Li CS, Park SH, Crane MM, Li L, Jin D, Boye-Doe A, Liu TY, Shibata Y, Lu H, Rapoport TA, Farese RV, Blackstone C, et al. A conserved role for atlastin GTPases in regulating lipid droplet size. Cell Reports. 3: 1465-75. PMID 23684613 DOI: 10.1016/j.celrep.2013.04.015  1
2012 Park E, Rapoport TA. Bacterial protein translocation requires only one copy of the SecY complex in vivo. The Journal of Cell Biology. 198: 881-93. PMID 22927464 DOI: 10.1083/jcb.201205140  1
2012 Liu TY, Bian X, Sun S, Hu X, Klemm RW, Prinz WA, Rapoport TA, Hu J. Lipid interaction of the C terminus and association of the transmembrane segments facilitate atlastin-mediated homotypic endoplasmic reticulum fusion. Proceedings of the National Academy of Sciences of the United States of America. 109: E2146-54. PMID 22802620 DOI: 10.1073/pnas.1208385109  1
2012 Anwar K, Klemm RW, Condon A, Severin KN, Zhang M, Ghirlando R, Hu J, Rapoport TA, Prinz WA. The dynamin-like GTPase Sey1p mediates homotypic ER fusion in S. cerevisiae. The Journal of Cell Biology. 197: 209-17. PMID 22508509 DOI: 10.1083/jcb.201111115  1
2012 Nguyen TT, Lewandowska A, Choi JY, Markgraf DF, Junker M, Bilgin M, Ejsing CS, Voelker DR, Rapoport TA, Shaw JM. Gem1 and ERMES do not directly affect phosphatidylserine transport from ER to mitochondria or mitochondrial inheritance. Traffic (Copenhagen, Denmark). 13: 880-90. PMID 22409400 DOI: 10.1111/j.1600-0854.2012.01352.x  1
2012 Park E, Rapoport TA. Mechanisms of Sec61/SecY-mediated protein translocation across membranes. Annual Review of Biophysics. 41: 21-40. PMID 22224601 DOI: 10.1146/annurev-biophys-050511-102312  1
2011 Hu J, Prinz WA, Rapoport TA. Weaving the web of ER tubules. Cell. 147: 1226-31. PMID 22153070 DOI: 10.1016/j.cell.2011.11.022  1
2011 Park E, Rapoport TA. Preserving the membrane barrier for small molecules during bacterial protein translocation. Nature. 473: 239-42. PMID 21562565 DOI: 10.1038/nature10014  1
2011 Stanley AM, Carvalho P, Rapoport T. Recognition of an ERAD-L substrate analyzed by site-specific in vivo photocrosslinking. Febs Letters. 585: 1281-6. PMID 21486563 DOI: 10.1016/j.febslet.2011.04.009  1
2011 Bian X, Klemm RW, Liu TY, Zhang M, Sun S, Sui X, Liu X, Rapoport TA, Hu J. Structures of the atlastin GTPase provide insight into homotypic fusion of endoplasmic reticulum membranes. Proceedings of the National Academy of Sciences of the United States of America. 108: 3976-81. PMID 21368113 DOI: 10.1073/pnas.1101643108  1
2011 Chen X, Tukachinsky H, Huang CH, Jao C, Chu YR, Tang HY, Mueller B, Schulman S, Rapoport TA, Salic A. Processing and turnover of the Hedgehog protein in the endoplasmic reticulum. The Journal of Cell Biology. 192: 825-38. PMID 21357747 DOI: 10.1083/jcb.201008090  1
2010 Shibata Y, Shemesh T, Prinz WA, Palazzo AF, Kozlov MM, Rapoport TA. Mechanisms determining the morphology of the peripheral ER. Cell. 143: 774-88. PMID 21111237 DOI: 10.1016/j.cell.2010.11.007  1
2010 Rapoport TA. A preliminary report on my life in science. Molecular Biology of the Cell. 21: 3770-2. PMID 21079005 DOI: 10.1091/mbc.E10-05-0398  1
2010 Carvalho P, Stanley AM, Rapoport TA. Retrotranslocation of a misfolded luminal ER protein by the ubiquitin-ligase Hrd1p. Cell. 143: 579-91. PMID 21074049 DOI: 10.1016/j.cell.2010.10.028  1
2010 Schulman S, Wang B, Li W, Rapoport TA. Vitamin K epoxide reductase prefers ER membrane-anchored thioredoxin-like redox partners. Proceedings of the National Academy of Sciences of the United States of America. 107: 15027-32. PMID 20696932 DOI: 10.1073/pnas.1009972107  1
2010 Li W, Schulman S, Dutton RJ, Boyd D, Beckwith J, Rapoport TA. Structure of a bacterial homologue of vitamin K epoxide reductase. Nature. 463: 507-12. PMID 20110994 DOI: 10.1038/nature08720  1
2010 Anderson KV, Dutcher SK, Greenberg ME, Karin M, Rapoport TA, Verdine GL, Zon LI. The Harvey Lectures: Delivered Under the Auspices of The Harvey Society of New York, 2006-2007 The Harvey Lectures: Delivered Under the Auspices of the Harvey Society of New York, 2006-2007. 1-189. DOI: 10.1002/9780470593042  1
2009 Bauer BW, Rapoport TA. Mapping polypeptide interactions of the SecA ATPase during translocation. Proceedings of the National Academy of Sciences of the United States of America. 106: 20800-5. PMID 19933328 DOI: 10.1073/pnas.0910550106  1
2009 Zimmer J, Rapoport TA. Conformational flexibility and peptide interaction of the translocation ATPase SecA. Journal of Molecular Biology. 394: 606-12. PMID 19850053 DOI: 10.1016/j.jmb.2009.10.024  1
2009 Hu J, Shibata Y, Zhu PP, Voss C, Rismanchi N, Prinz WA, Rapoport TA, Blackstone C. A class of dynamin-like GTPases involved in the generation of the tubular ER network. Cell. 138: 549-61. PMID 19665976 DOI: 10.1016/j.cell.2009.05.025  1
2009 Shibata Y, Hu J, Kozlov MM, Rapoport TA. Mechanisms shaping the membranes of cellular organelles. Annual Review of Cell and Developmental Biology. 25: 329-54. PMID 19575675 DOI: 10.1146/annurev.cellbio.042308.113324  1
2008 Erlandson KJ, Miller SB, Nam Y, Osborne AR, Zimmer J, Rapoport TA. A role for the two-helix finger of the SecA ATPase in protein translocation. Nature. 455: 984-7. PMID 18923526 DOI: 10.1038/nature07439  1
2008 Zimmer J, Nam Y, Rapoport TA. Structure of a complex of the ATPase SecA and the protein-translocation channel. Nature. 455: 936-43. PMID 18923516 DOI: 10.1038/nature07335  1
2008 Rapoport TA. Protein transport across the endoplasmic reticulum membrane. The Febs Journal. 275: 4471-8. PMID 18671729 DOI: 10.1111/j.1742-4658.2008.06588.x  1
2008 Ménétret JF, Hegde RS, Aguiar M, Gygi SP, Park E, Rapoport TA, Akey CW. Single copies of Sec61 and TRAP associate with a nontranslating mammalian ribosome. Structure (London, England : 1993). 16: 1126-37. PMID 18611385 DOI: 10.1016/j.str.2008.05.003  1
2008 Shibata Y, Voss C, Rist JM, Hu J, Rapoport TA, Prinz WA, Voeltz GK. The reticulon and DP1/Yop1p proteins form immobile oligomers in the tubular endoplasmic reticulum. The Journal of Biological Chemistry. 283: 18892-904. PMID 18442980 DOI: 10.1074/jbc.M800986200  1
2008 Goder V, Carvalho P, Rapoport TA. The ER-associated degradation component Der1p and its homolog Dfm1p are contained in complexes with distinct cofactors of the ATPase Cdc48p. Febs Letters. 582: 1575-80. PMID 18407841 DOI: 10.1016/j.febslet.2008.03.056  1
2008 Erlandson KJ, Or E, Osborne AR, Rapoport TA. Analysis of polypeptide movement in the SecY channel during SecA-mediated protein translocation. The Journal of Biological Chemistry. 283: 15709-15. PMID 18359943 DOI: 10.1074/jbc.M710356200  1
2008 Hu J, Shibata Y, Voss C, Shemesh T, Li Z, Coughlin M, Kozlov MM, Rapoport TA, Prinz WA. Membrane proteins of the endoplasmic reticulum induce high-curvature tubules. Science (New York, N.Y.). 319: 1247-50. PMID 18309084 DOI: 10.1126/science.1153634  1
2007 Burton BM, Marquis KA, Sullivan NL, Rapoport TA, Rudner DZ. The ATPase SpoIIIE transports DNA across fused septal membranes during sporulation in Bacillus subtilis. Cell. 131: 1301-12. PMID 18160039 DOI: 10.1016/j.cell.2007.11.009  1
2007 Ménétret JF, Schaletzky J, Clemons WM, Osborne AR, Skånland SS, Denison C, Gygi SP, Kirkpatrick DS, Park E, Ludtke SJ, Rapoport TA, Akey CW. Ribosome binding of a single copy of the SecY complex: implications for protein translocation. Molecular Cell. 28: 1083-92. PMID 18158904 DOI: 10.1016/j.molcel.2007.10.034  1
2007 Palazzo AF, Springer M, Shibata Y, Lee CS, Dias AP, Rapoport TA. The signal sequence coding region promotes nuclear export of mRNA. Plos Biology. 5: e322. PMID 18052610 DOI: 10.1371/journal.pbio.0050322  1
2007 Rapoport TA. Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranes. Nature. 450: 663-9. PMID 18046402 DOI: 10.1038/nature06384  1
2007 Ye J, Cho SH, Fuselier J, Li W, Beckwith J, Rapoport TA. Crystal structure of an unusual thioredoxin protein with a zinc finger domain. The Journal of Biological Chemistry. 282: 34945-51. PMID 17913712 DOI: 10.1074/jbc.M704044200  1
2007 Li W, Schulman S, Boyd D, Erlandson K, Beckwith J, Rapoport TA. The plug domain of the SecY protein stabilizes the closed state of the translocation channel and maintains a membrane seal. Molecular Cell. 26: 511-21. PMID 17531810 DOI: 10.1016/j.molcel.2007.05.002  1
2007 Saparov SM, Erlandson K, Cannon K, Schaletzky J, Schulman S, Rapoport TA, Pohl P. Determining the conductance of the SecY protein translocation channel for small molecules. Molecular Cell. 26: 501-9. PMID 17531809 DOI: 10.1016/j.molcel.2007.03.022  1
2007 Or E, Rapoport T. Cross-linked SecA dimers are not functional in protein translocation Febs Letters. 581: 2616-2620. PMID 17511989 DOI: 10.1016/j.febslet.2007.04.083  1
2007 Osborne AR, Rapoport TA. Protein translocation is mediated by oligomers of the SecY complex with one SecY copy forming the channel. Cell. 129: 97-110. PMID 17418789 DOI: 10.1016/j.cell.2007.02.036  1
2007 Voeltz GK, Prinz WA, Shibata Y, Rist JM, Rapoport TA. A Class of Membrane Proteins Shaping the Tubular Endoplasmic Reticulum (DOI:10.1016/j.cell.2005.11.047) Cell. 130: 754. DOI: 10.1016/j.cell.2007.08.004  1
2006 Rapoport TA. Protein transport in and out of the endoplasmic reticulum. Harvey Lectures. 102: 51-72. PMID 20166563 DOI: 10.1002/9780470593042.ch3  1
2006 Zimmer J, Li W, Rapoport TA. A novel dimer interface and conformational changes revealed by an X-ray structure of B. subtilis SecA. Journal of Molecular Biology. 364: 259-65. PMID 16989859 DOI: 10.1016/j.jmb.2006.08.044  1
2006 Shibata Y, Voeltz GK, Rapoport TA. Rough sheets and smooth tubules. Cell. 126: 435-9. PMID 16901774 DOI: 10.1016/j.cell.2006.07.019  1
2006 Carvalho P, Goder V, Rapoport TA. Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins. Cell. 126: 361-73. PMID 16873066 DOI: 10.1016/j.cell.2006.05.043  1
2006 Flierman D, Coleman CS, Pickart CM, Rapoport TA, Chau V. E2-25K mediates US11-triggered retro-translocation of MHC class I heavy chains in a permeabilized cell system. Proceedings of the National Academy of Sciences of the United States of America. 103: 11589-94. PMID 16868077 DOI: 10.1073/pnas.0605215103  1
2006 Schaletzky J, Rapoport TA. Ribosome binding to and dissociation from translocation sites of the endoplasmic reticulum membrane. Molecular Biology of the Cell. 17: 3860-9. PMID 16822833 DOI: 10.1091/mbc.E06-05-0439  1
2006 Voeltz GK, Prinz WA, Shibata Y, Rist JM, Rapoport TA. A class of membrane proteins shaping the tubular endoplasmic reticulum. Cell. 124: 573-86. PMID 16469703 DOI: 10.1016/j.cell.2005.11.047  1
2005 Osborne AR, Rapoport TA, van den Berg B. Protein translocation by the Sec61/SecY channel. Annual Review of Cell and Developmental Biology. 21: 529-50. PMID 16212506 DOI: 10.1146/annurev.cellbio.21.012704.133214  1
2005 Ye Y, Shibata Y, Kikkert M, van Voorden S, Wiertz E, Rapoport TA. Recruitment of the p97 ATPase and ubiquitin ligases to the site of retrotranslocation at the endoplasmic reticulum membrane. Proceedings of the National Academy of Sciences of the United States of America. 102: 14132-8. PMID 16186510 DOI: 10.1073/pnas.0505006102  1
2005 Kothe M, Ye Y, Wagner JS, De Luca HE, Kern E, Rapoport TA, Lencer WI. Role of p97 AAA-ATPase in the retrotranslocation of the cholera toxin A1 chain, a non-ubiquitinated substrate. The Journal of Biological Chemistry. 280: 28127-32. PMID 15932873 DOI: 10.1074/jbc.M503138200  1
2005 Cannon KS, Or E, Clemons WM, Shibata Y, Rapoport TA. Disulfide bridge formation between SecY and a translocating polypeptide localizes the translocation pore to the center of SecY. The Journal of Cell Biology. 169: 219-25. PMID 15851514 DOI: 10.1083/jcb.200412019  1
2005 Ménétret JF, Hegde RS, Heinrich SU, Chandramouli P, Ludtke SJ, Rapoport TA, Akey CW. Architecture of the ribosome-channel complex derived from native membranes. Journal of Molecular Biology. 348: 445-57. PMID 15811380 DOI: 10.1016/j.jmb.2005.02.053  0.68
2005 Heinrich R, Rapoport TA. Generation of nonidentical compartments in vesicular transport systems. The Journal of Cell Biology. 168: 271-80. PMID 15657397 DOI: 10.1083/jcb.200409087  1
2005 Or E, Boyd D, Gon S, Beckwith J, Rapoport T. The bacterial ATPase SecA functions as a monomer in protein translocation Journal of Biological Chemistry. 280: 9097-9105. PMID 15618215 DOI: 10.1074/jbc.M413947200  1
2004 Ye J, Osborne AR, Groll M, Rapoport TA. RecA-like motor ATPases--lessons from structures. Biochimica Et Biophysica Acta. 1659: 1-18. PMID 15511523 DOI: 10.1016/j.bbabio.2004.06.003  1
2004 Rapoport TA, Goder V, Heinrich SU, Matlack KE. Membrane-protein integration and the role of the translocation channel. Trends in Cell Biology. 14: 568-75. PMID 15450979 DOI: 10.1016/j.tcb.2004.09.002  1
2004 Clemons WM, Ménétret JF, Akey CW, Rapoport TA. Structural insight into the protein translocation channel. Current Opinion in Structural Biology. 14: 390-6. PMID 15313231 DOI: 10.1016/j.sbi.2004.07.006  1
2004 Osborne AR, Clemons WM, Rapoport TA. A large conformational change of the translocation ATPase SecA. Proceedings of the National Academy of Sciences of the United States of America. 101: 10937-42. PMID 15256599 DOI: 10.1073/pnas.0401742101  1
2004 Ye Y, Shibata Y, Yun C, Ron D, Rapoport TA. A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol. Nature. 429: 841-7. PMID 15215856 DOI: 10.1038/nature02656  1
2004 van den Berg B, Black PN, Clemons WM, Rapoport TA. Crystal structure of the long-chain fatty acid transporter FadL. Science (New York, N.Y.). 304: 1506-9. PMID 15178802 DOI: 10.1126/science.1097524  1
2004 Van den Berg B, Clemons WM, Collinson I, Modis Y, Hartmann E, Harrison SC, Rapoport TA. X-ray structure of a protein-conducting channel. Nature. 427: 36-44. PMID 14661030 DOI: 10.1038/nature02218  1
2004 Le Gall S, Neuhof A, Rapoport T. The Endoplasmic Reticulum Membrane Is Permeable to Small Molecules Molecular Biology of the Cell. 15: 447-455. PMID 14617815 DOI: 10.1091/mbc.E03-05-0325  1
2004 Plath K, Wilkinson BM, Stirling CJ, Rapoport TA. Interactions between Sec complex and prepro-alpha-factor during posttranslational protein transport into the endoplasmic reticulum. Molecular Biology of the Cell. 15: 1-10. PMID 14617809 DOI: 10.1091/mbc.E03-06-0390  1
2003 Fujinaga Y, Wolf AA, Rodighiero C, Wheeler H, Tsai B, Allen L, Jobling MG, Rapoport T, Holmes RK, Lencer WI. Gangliosides That Associate with Lipid Rafts Mediate Transport of Cholera and Related Toxins from the Plasma Membrane to Endoplasmic Reticulm Molecular Biology of the Cell. 14: 4783-4793. PMID 13679513 DOI: 10.1091/mbc.E03-06-0354  1
2003 Tsai B, Gilbert JM, Stehle T, Lencer W, Benjamin TL, Rapoport TA. Gangliosides are receptors for murine polyoma virus and SV40. The Embo Journal. 22: 4346-55. PMID 12941687 DOI: 10.1093/emboj/cdg439  1
2003 Heinrich SU, Rapoport TA. Cooperation of transmembrane segments during the integration of a double-spanning protein into the ER membrane. The Embo Journal. 22: 3654-63. PMID 12853480 DOI: 10.1093/emboj/cdg346  1
2003 Ye Y, Meyer HH, Rapoport TA. Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains. The Journal of Cell Biology. 162: 71-84. PMID 12847084 DOI: 10.1083/jcb.200302169  1
2003 Flierman D, Ye Y, Dai M, Chau V, Rapoport TA. Polyubiquitin serves as a recognition signal, rather than a ratcheting molecule, during retrotranslocation of proteins across the endoplasmic reticulum membrane. The Journal of Biological Chemistry. 278: 34774-82. PMID 12813030 DOI: 10.1074/jbc.M303360200  1
2002 Morgan DG, Ménétret JF, Neuhof A, Rapoport TA, Akey CW. Structure of the mammalian ribosome-channel complex at 17A resolution. Journal of Molecular Biology. 324: 871-86. PMID 12460584  0.64
2002 Rodighiero C, Tsai B, Rapoport TA, Lencer WI. Role of ubiquitination in retro-translocation of cholera toxin and escape of cytosolic degradation. Embo Reports. 3: 1222-7. PMID 12446567 DOI: 10.1093/embo-reports/kvf239  1
2002 Tsai B, Rapoport TA. Unfolded cholera toxin is transferred to the ER membrane and released from protein disulfide isomerase upon oxidation by Ero1. The Journal of Cell Biology. 159: 207-16. PMID 12403808 DOI: 10.1083/jcb.200207120  1
2002 Voeltz GK, Rolls MM, Rapoport TA. Structural organization of the endoplasmic reticulum. Embo Reports. 3: 944-50. PMID 12370207 DOI: 10.1093/embo-reports/kvf202  1
2002 Or E, Navon A, Rapoport T. Dissociation of the dimeric SecA ATPase during protein translocation across the bacterial membrane Embo Journal. 21: 4470-4479. PMID 12198149 DOI: 10.1093/emboj/cdf471  1
2002 Breyton C, Haase W, Rapoport TA, Kühlbrandt W, Collinson I. Three-dimensional structure of the bacterial protein-translocation complex SecYEG. Nature. 418: 662-5. PMID 12167867 DOI: 10.1038/nature00827  1
2002 Stein PA, Toret CP, Salic AN, Rolls MM, Rapoport TA. A novel centrosome-associated protein with affinity for microtubules. Journal of Cell Science. 115: 3389-402. PMID 12154070  1
2002 Rapoport T. Profile: Tom Rapoport interviewed by Rabiya S. Tuma Trends in Cell Biology. 12: 288-289. PMID 12074889  1
2002 Heinrich R, Neel BG, Rapoport TA. Mathematical models of protein kinase signal transduction. Molecular Cell. 9: 957-70. PMID 12049733 DOI: 10.1016/S1097-2765(02)00528-2  1
2002 Rolls MM, Hall DH, Victor M, Stelzer EH, Rapoport TA. Targeting of rough endoplasmic reticulum membrane proteins and ribosomes in invertebrate neurons. Molecular Biology of the Cell. 13: 1778-91. PMID 12006669 DOI: 10.1091/mbc.01-10-0514  1
2002 Tsai B, Ye Y, Rapoport TA. Retro-translocation of proteins from the endoplasmic reticulum into the cytosol. Nature Reviews. Molecular Cell Biology. 3: 246-55. PMID 11994744 DOI: 10.1038/nrm780  1
2001 Horwich AL, Fenton WA, Rapoport TA. Protein folding taking shape. Workshop on molecular chaperones. Embo Reports. 2: 1068-73. PMID 11743017 DOI: 10.1093/embo-reports/kve253  1
2001 Ye Y, Meyer HH, Rapoport TA. The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol. Nature. 414: 652-6. PMID 11740563 DOI: 10.1038/414652a  1
2001 Verhey KJ, Rapoport TA. Kinesin carries the signal. Trends in Biochemical Sciences. 26: 545-50. PMID 11551791 DOI: 10.1016/S0968-0004(01)01931-4  1
2001 Shamu CE, Flierman D, Ploegh HL, Rapoport TA, Chau V. Polyubiquitination is required for US11-dependent movement of MHC class I heavy chain from endoplasmic reticulum into cytosol. Molecular Biology of the Cell. 12: 2546-55. PMID 11514634  1
2001 Collinson I, Breyton C, Duong F, Tziatzios C, Schubert D, Or E, Rapoport T, Kühlbrandt W. Projection structure and oligomeric properties of a bacterial core protein translocase. The Embo Journal. 20: 2462-71. PMID 11350935 DOI: 10.1093/emboj/20.10.2462  1
2001 Tsai B, Rodighiero C, Lencer WI, Rapoport TA. Protein disulfide isomerase acts as a redox-dependent chaperone to unfold cholera toxin. Cell. 104: 937-48. PMID 11290330 DOI: 10.1016/S0092-8674(01)00289-6  1
2001 Verhey KJ, Meyer D, Deehan R, Blenis J, Schnapp BJ, Rapoport TA, Margolis B. Cargo of kinesin identified as JIP scaffolding proteins and associated signaling molecules. The Journal of Cell Biology. 152: 959-70. PMID 11238452 DOI: 10.1083/jcb.152.5.959  1
2001 Liebermeister W, Rapoport TA, Heinrich R. Ratcheting in post-translational protein translocation: a mathematical model. Journal of Molecular Biology. 305: 643-56. PMID 11152619 DOI: 10.1006/jmbi.2000.4302  1
2000 Menetret JF, Neuhof A, Morgan DG, Plath K, Radermacher M, Rapoport TA, Akey CW. The structure of ribosome-channel complexes engaged in protein translocation. Molecular Cell. 6: 1219-32. PMID 11106759  1
2000 Plath K, Rapoport TA. Spontaneous release of cytosolic proteins from posttranslational substrates before their transport into the endoplasmic reticulum. The Journal of Cell Biology. 151: 167-78. PMID 11018062 DOI: 10.1083/jcb.151.1.167  1
2000 Heinrich SU, Mothes W, Brunner J, Rapoport TA. The Sec61p complex mediates the integration of a membrane protein by allowing lipid partitioning of the transmembrane domain. Cell. 102: 233-44. PMID 10943843  1
2000 Prinz WA, Grzyb L, Veenhuis M, Kahana JA, Silver PA, Rapoport TA. Mutants affecting the structure of the cortical endoplasmic reticulum in Saccharomyces cerevisiae. The Journal of Cell Biology. 150: 461-74. PMID 10931860 DOI: 10.1083/jcb.150.3.461  1
2000 Morgan DG, Ménétret JF, Radermacher M, Neuhof A, Akey IV, Rapoport TA, Akey CW. A comparison of the yeast and rabbit 80 S ribosome reveals the topology of the nascent chain exit tunnel, inter-subunit bridges and mammalian rRNA expansion segments. Journal of Molecular Biology. 301: 301-21. PMID 10926511 DOI: 10.1006/jmbi.2000.3947  1
2000 Prinz A, Behrens C, Rapoport TA, Hartmann E, Kalies KU. Evolutionarily conserved binding of ribosomes to the translocation channel via the large ribosomal RNA. The Embo Journal. 19: 1900-6. PMID 10775273 DOI: 10.1093/emboj/19.8.1900  1
2000 Dreier L, Rapoport TA. In vitro formation of the endoplasmic reticulum occurs independently of microtubules by a controlled fusion reaction. The Journal of Cell Biology. 148: 883-98. PMID 10704440 DOI: 10.1083/jcb.148.5.883  1
1999 Rapoport TA, Matlack KE, Plath K, Misselwitz B, Staeck O. Posttranslational protein translocation across the membrane of the endoplasmic reticulum. Biological Chemistry. 380: 1143-50. PMID 10595576 DOI: 10.1515/BC.1999.145  1
1999 Shamu CE, Story CM, Rapoport TA, Ploegh HL. The pathway of US11-dependent degradation of MHC class I heavy chains involves a ubiquitin-conjugated intermediate. The Journal of Cell Biology. 147: 45-58. PMID 10508854 DOI: 10.1083/jcb.147.1.45  1
1999 Schröder K, Martoglio B, Hofmann M, Hölscher C, Hartmann E, Prehn S, Rapoport TA, Dobberstein B. Control of glycosylation of MHC class II-associated invariant chain by translocon-associated RAMP4. The Embo Journal. 18: 4804-15. PMID 10469658 DOI: 10.1093/emboj/18.17.4804  1
1999 Rolls MM, Stein PA, Taylor SS, Ha E, McKeon F, Rapoport TA. A visual screen of a GFP-fusion library identifies a new type of nuclear envelope membrane protein. The Journal of Cell Biology. 146: 29-44. PMID 10402458 DOI: 10.1083/jcb.146.1.29  1
1999 Misselwitz B, Staeck O, Matlack KE, Rapoport TA. Interaction of BiP with the J-domain of the Sec63p component of the endoplasmic reticulum protein translocation complex. The Journal of Biological Chemistry. 274: 20110-5. PMID 10400622 DOI: 10.1074/jbc.274.29.20110  1
1999 Matlack KE, Misselwitz B, Plath K, Rapoport TA. BiP acts as a molecular ratchet during posttranslational transport of prepro-alpha factor across the ER membrane. Cell. 97: 553-64. PMID 10367885 DOI: 10.1016/S0092-8674(00)80767-9  1
1999 Meyer TH, Ménétret JF, Breitling R, Miller KR, Akey CW, Rapoport TA. The bacterial SecY/E translocation complex forms channel-like structures similar to those of the eukaryotic Sec61p complex. Journal of Molecular Biology. 285: 1789-800. PMID 9917412 DOI: 10.1006/jmbi.1998.2413  1
1998 Misselwitz B, Staeck O, Rapoport TA. J proteins catalytically activate Hsp70 molecules to trap a wide range of peptide sequences. Molecular Cell. 2: 593-603. PMID 9844632  1
1998 Verhey KJ, Lizotte DL, Abramson T, Barenboim L, Schnapp BJ, Rapoport TA. Light chain-dependent regulation of Kinesin's interaction with microtubules. The Journal of Cell Biology. 143: 1053-66. PMID 9817761 DOI: 10.1083/jcb.143.4.1053  1
1998 Plath K, Mothes W, Wilkinson BM, Stirling CJ, Rapoport TA. Signal sequence recognition in posttranslational protein transport across the yeast ER membrane. Cell. 94: 795-807. PMID 9753326 DOI: 10.1016/S0092-8674(00)81738-9  1
1998 Mothes W, Jungnickel B, Brunner J, Rapoport TA. Signal sequence recognition in cotranslational translocation by protein components of the endoplasmic reticulum membrane. The Journal of Cell Biology. 142: 355-64. PMID 9679136 DOI: 10.1083/jcb.142.2.355  1
1998 Kalies KU, Rapoport TA, Hartmann E. The beta subunit of the Sec61 complex facilitates cotranslational protein transport and interacts with the signal peptidase during translocation. The Journal of Cell Biology. 141: 887-94. PMID 9585408 DOI: 10.1083/jcb.141.4.887  1
1998 Hegde RS, Voigt S, Rapoport TA, Lingappa VR. TRAM regulates the exposure of nascent secretory proteins to the cytosol during translocation into the endoplasmic reticulum. Cell. 92: 621-31. PMID 9506517 DOI: 10.1016/S0092-8674(00)81130-7  1
1998 Matlack KE, Mothes W, Rapoport TA. Protein translocation: tunnel vision. Cell. 92: 381-90. PMID 9476897 DOI: 10.1016/S0092-8674(00)80930-7  1
1998 Neuhof A, Rolls MM, Jungnickel B, Kalies KU, Rapoport TA. Binding of signal recognition particle gives ribosome/nascent chain complexes a competitive advantage in endoplasmic reticulum membrane interaction. Molecular Biology of the Cell. 9: 103-15. PMID 9436994  1
1997 Matlack KE, Plath K, Misselwitz B, Rapoport TA. Protein transport by purified yeast Sec complex and Kar2p without membranes. Science (New York, N.Y.). 277: 938-41. PMID 9252322 DOI: 10.1126/science.277.5328.938  1
1997 Mothes W, Heinrich SU, Graf R, Nilsson I, von Heijne G, Brunner J, Rapoport TA. Molecular mechanism of membrane protein integration into the endoplasmic reticulum. Cell. 89: 523-33. PMID 9160744  1
1997 Rapoport TA. Components and mechanisms involved in protein translocation across the endoplasmic reticulum membrane Faseb Journal. 11: A785.  1
1996 Wiertz EJ, Tortorella D, Bogyo M, Yu J, Mothes W, Jones TR, Rapoport TA, Ploegh HL. Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction. Nature. 384: 432-8. PMID 8945469 DOI: 10.1038/384432a0  1
1996 Hanein D, Matlack KE, Jungnickel B, Plath K, Kalies KU, Miller KR, Rapoport TA, Akey CW. Oligomeric rings of the Sec61p complex induced by ligands required for protein translocation. Cell. 87: 721-32. PMID 8929540 DOI: 10.1016/S0092-8674(00)81391-4  1
1996 Rapoport TA, Jungnickel B, Kutay U. Protein transport across the eukaryotic endoplasmic reticulum and bacterial inner membranes. Annual Review of Biochemistry. 65: 271-303. PMID 8811181 DOI: 10.1146/annurev.bi.65.070196.001415  1
1996 Rapoport TA, Rolls MM, Jungnickel B. Approaching the mechanism of protein transport across the ER membrane. Current Opinion in Cell Biology. 8: 499-504. PMID 8791447 DOI: 10.1016/S0955-0674(96)80027-5  1
1996 Voigt S, Jungnickel B, Hartmann E, Rapoport TA. Signal sequence-dependent function of the TRAM protein during early phases of protein transport across the endoplasmic reticulum membrane. The Journal of Cell Biology. 134: 25-35. PMID 8698819 DOI: 10.1083/jcb.134.1.25  1
1996 Whitley P, Grahn E, Kutay U, Rapoport TA, von Heijne G. A 12-residue-long polyleucine tail is sufficient to anchor synaptobrevin to the endoplasmic reticulum membrane. The Journal of Biological Chemistry. 271: 7583-6. PMID 8631791 DOI: 10.1074/jbc.271.13.7583  1
1996 Bacher G, Lütcke H, Jungnickel B, Rapoport TA, Dobberstein B. Regulation by the ribosome of the GTPase of the signal-recognition particle during protein targeting. Nature. 381: 248-51. PMID 8622769 DOI: 10.1038/381248a0  1
1996 Finke K, Plath K, Panzner S, Prehn S, Rapoport TA, Hartmann E, Sommer T. A second trimeric complex containing homologs of the Sec61p complex functions in protein transport across the ER membrane of S. cerevisiae. The Embo Journal. 15: 1482-94. PMID 8612571  1
1995 Panzner S, Dreier L, Hartmann E, Kostka S, Rapoport TA. Posttranslational protein transport into the endoplasmic reticulum. Cold Spring Harbor Symposia On Quantitative Biology. 60: 31-40. PMID 8824375  1
1995 Kutay U, Ahnert-Hilger G, Hartmann E, Wiedenmann B, Rapoport TA. Transport route for synaptobrevin via a novel pathway of insertion into the endoplasmic reticulum membrane. The Embo Journal. 14: 217-23. PMID 7835332  1
1995 Panzner S, Dreier L, Hartmann E, Kostka S, Rapoport TA. Posttranslational protein transport in yeast reconstituted with a purified complex of Sec proteins and Kar2p. Cell. 81: 561-70. PMID 7758110 DOI: 10.1016/0092-8674(95)90077-2  1
1995 Lyko F, Martoglio B, Jungnickel B, Rapoport TA, Dobberstein B. Signal sequence processing in rough microsomes. The Journal of Biological Chemistry. 270: 19873-8. PMID 7650000 DOI: 10.1074/jbc.270.34.19873  1
1995 Jungnickel B, Rapoport TA. A posttargeting signal sequence recognition event in the endoplasmic reticulum membrane. Cell. 82: 261-70. PMID 7628015 DOI: 10.1016/0092-8674(95)90313-5  1
1994 Jungnickel B, Rapoport TA, Hartmann E. Protein translocation: common themes from bacteria to man. Febs Letters. 346: 73-7. PMID 8206162 DOI: 10.1016/0014-5793(94)00367-X  1
1994 Hartmann E, Sommer T, Prehn S, Görlich D, Jentsch S, Rapoport TA. Evolutionary conservation of components of the protein translocation complex. Nature. 367: 654-7. PMID 8107851 DOI: 10.1038/367654a0  1
1994 Mothes W, Prehn S, Rapoport TA. Systematic probing of the environment of a translocating secretory protein during translocation through the ER membrane. The Embo Journal. 13: 3973-82. PMID 8076593  1
1994 Kalies KU, Görlich D, Rapoport TA. Binding of ribosomes to the rough endoplasmic reticulum mediated by the Sec61p-complex. The Journal of Cell Biology. 126: 925-34. PMID 8051212 DOI: 10.1083/jcb.126.4.925  1
1993 Kutay U, Hartmann E, Rapoport TA. A class of membrane proteins with a C-terminal anchor. Trends in Cell Biology. 3: 72-5. PMID 14731773  1
1993 High S, Andersen SS, Görlich D, Hartmann E, Prehn S, Rapoport TA, Dobberstein B. Sec61p is adjacent to nascent type I and type II signal-anchor proteins during their membrane insertion. The Journal of Cell Biology. 121: 743-50. PMID 8491769  1
1993 Jungnickel B, Rapoport TA. DIDS (4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid) inhibits an early step of protein translocation across the mammalian ER membrane. Febs Letters. 329: 268-72. PMID 8396042 DOI: 10.1016/0014-5793(93)80235-M  1
1993 High S, Martoglio B, Görlich D, Andersen SS, Ashford AJ, Giner A, Hartmann E, Prehn S, Rapoport TA, Dobberstein B. Site-specific photocross-linking reveals that Sec61p and TRAM contact different regions of a membrane-inserted signal sequence. The Journal of Biological Chemistry. 268: 26745-51. PMID 8253810  1
1993 Görlich D, Rapoport TA. Protein translocation into proteoliposomes reconstituted from purified components of the endoplasmic reticulum membrane. Cell. 75: 615-30. PMID 8242738 DOI: 10.1016/0092-8674(93)90483-7  1
1993 Hartmann E, Görlich D, Kostka S, Otto A, Kraft R, Knespel S, Bürger E, Rapoport TA, Prehn S. A tetrameric complex of membrane proteins in the endoplasmic reticulum. European Journal of Biochemistry / Febs. 214: 375-81. PMID 7916687  1
1992 Müsch A, Wiedmann M, Rapoport TA. Yeast Sec proteins interact with polypeptides traversing the endoplasmic reticulum membrane. Cell. 69: 343-52. PMID 1568249 DOI: 10.1016/0092-8674(92)90414-8  1
1992 Görlich D, Prehn S, Hartmann E, Kalies KU, Rapoport TA. A mammalian homolog of SEC61p and SECYp is associated with ribosomes and nascent polypeptides during translocation. Cell. 71: 489-503. PMID 1423609 DOI: 10.1016/0092-8674(92)90517-G  1
1992 Rapoport TA. Transport of proteins across the endoplasmic reticulum membrane. Science (New York, N.Y.). 258: 931-6. PMID 1332192  1
1992 Hartmann E, Rapoport TA, Prehn S. Signal sequence identified. Nature. 358: 198. PMID 1321345 DOI: 10.1038/358198a0  1
1992 Rapoport TA, Görlich D, Müsch A, Hartmann E, Prehn S, Wiedmann M, Otto A, Kostka S, Kraft R. Components and mechanism of protein translocation across the ER membrane. Antonie Van Leeuwenhoek. 61: 119-22. PMID 1316096 DOI: 10.1007/BF00580618  1
1992 Görlich D, Hartmann E, Prehn S, Rapoport TA. A protein of the endoplasmic reticulum involved early in polypeptide translocation. Nature. 357: 47-52. PMID 1315422 DOI: 10.1038/357047a0  1
1992 Hartmann E, Rapoport TA. Chapter 10 Translocation of proteins through the endoplasmic reticulum membrane: investigation of their molecular environment by cross-linking New Comprehensive Biochemistry. 22: 119-127. DOI: 10.1016/S0167-7306(08)60087-3  1
1991 Görlich D, Kurzchalia TV, Wiedmann M, Rapoport TA. Probing the molecular environment of translocating polypeptide chains by cross-linking. Methods in Cell Biology. 34: 241-62. PMID 1943803  1
1991 Rapoport TA. Protein transport across the endoplasmic reticulum membrane: facts, models, mysteries. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 5: 2792-8. PMID 1916103  1
1991 High S, Görlich D, Wiedmann M, Rapoport TA, Dobberstein B. The identification of proteins in the proximity of signal-anchor sequences during their targeting to and insertion into the membrane of the ER. The Journal of Cell Biology. 113: 35-44. PMID 1848866  1
1991 Rapoport TA. Protein translocation. A bacterium catches up. Nature. 349: 107-8. PMID 1846029 DOI: 10.1038/349107a0  1
1990 Rapoport TA. Protein transport across the ER membrane. Trends in Biochemical Sciences. 15: 355-8. PMID 2238046 DOI: 10.1016/0968-0004(90)90076-N  1
1990 Görlich D, Prehn S, Hartmann E, Herz J, Otto A, Kraft R, Wiedmann M, Knespel S, Dobberstein B, Rapoport TA. The signal sequence receptor has a second subunit and is part of a translocation complex in the endoplasmic reticulum as probed by bifunctional reagents. The Journal of Cell Biology. 111: 2283-94. PMID 2177473  1
1990 Prehn S, Herz J, Hartmann E, Kurzchalia TV, Frank R, Roemisch K, Dobberstein B, Rapoport TA. Structure and biosynthesis of the signal-sequence receptor. European Journal of Biochemistry / Febs. 188: 439-45. PMID 2156703  1
1990 Muesch A, Hartmann E, Rohde K, Rubartelli A, Sitia R, Rapoport TA. A novel pathway for secretory proteins? Trends in Biochemical Sciences. 15: 86-8. PMID 2139259 DOI: 10.1016/0968-0004(90)90186-F  1
1990 Vogel F, Hartmann E, Görlich D, Rapoport TA. Segregation of the signal sequence receptor protein in the rough endoplasmic reticulum membrane. European Journal of Cell Biology. 53: 197-202. PMID 1964414  1
1989 Hartmann E, Rapoport TA, Lodish HF. Predicting the orientation of eukaryotic membrane-spanning proteins. Proceedings of the National Academy of Sciences of the United States of America. 86: 5786-90. PMID 2762295  1
1989 Rapoport TA, Wiedmann M, Kurzchalia TV, Hartmann E. Signal recognition in protein translocation across the endoplasmic reticulum membrane. Biochemical Society Transactions. 17: 325-8. PMID 2666191  1
1989 Wiedmann M, Goerlich D, Hartmann E, Kurzchalia TV, Rapoport TA. Photocrosslinking demonstrates proximity of a 34 kDa membrane protein to different portions of preprolactin during translocation through the endoplasmic reticulum. Febs Letters. 257: 263-8. PMID 2583273 DOI: 10.1016/0014-5793(89)81549-2  1
1989 Hartmann E, Wiedmann M, Rapoport TA. A membrane component of the endoplasmic reticulum that may be essential for protein translocation. The Embo Journal. 8: 2225-9. PMID 2551677  1
1989 Bernstein HD, Rapoport TA, Walter P. Cytosolic protein translocation factors. Is SRP still unique? Cell. 58: 1017-9. PMID 2550141 DOI: 10.1016/0092-8674(89)90497-2  1
1989 Huth A, Petrukhin KE, Modyanov NN, Rapoport TA. SRP-dependent membrane integration of the beta-subunit of Na+,K+-ATPase. Biomedica Biochimica Acta. 48: 77-84. PMID 2549983  1
1988 Bassüner R, Bäumlein H, Huth A, Jung R, Wobus U, Rapoport TA, Saalbach G, Müntz K. Abundant embryonic mRNA in field bean (Vicia faba L.) codes for a new class of seed proteins: cDNA cloning and characterization of the primary translation product. Plant Molecular Biology. 11: 321-34. PMID 24272345 DOI: 10.1007/BF00027389  1
1988 Kurzchalia TV, Wiedmann M, Breter H, Zimmermann W, Bauschke E, Rapoport TA. tRNA-mediated labelling of proteins with biotin. A nonradioactive method for the detection of cell-free translation products. European Journal of Biochemistry / Febs. 172: 663-8. PMID 3350017  1
1988 Wiedmann M, Wiedmann B, Voigt S, Wachter E, Müller HG, Rapoport TA. Post-translational transport of proteins into microsomal membranes of Candida maltosa. The Embo Journal. 7: 1763-8. PMID 3169003  1
1987 Prehn S, Wiedmann M, Rapoport TA, Zwieb C. Protein translocation across wheat germ microsomal membranes requires an SRP-like component. The Embo Journal. 6: 2093-7. PMID 16453782  0.72
1987 Wiedmann M, Kurzchalia TV, Bielka H, Rapoport TA. Direct probing of the interaction between the signal sequence of nascent preprolactin and the signal recognition particle by specific cross-linking. The Journal of Cell Biology. 104: 201-8. PMID 3643215  1
1987 Wiedmann M, Kurzchalia TV, Hartmann E, Rapoport TA. A signal sequence receptor in the endoplasmic reticulum membrane. Nature. 328: 830-3. PMID 3041222 DOI: 10.1038/328830a0  1
1987 Rapoport TA, Heinrich R, Walter P, Schulmeister T. Mathematical modeling of the effects of the signal recognition particle on translation and translocation of proteins across the endoplasmic reticulum membrane. Journal of Molecular Biology. 195: 621-36. PMID 2821280 DOI: 10.1016/0022-2836(87)90186-0  1
1986 Kurzchalia TV, Wiedmann M, Girshovich AS, Bochkareva ES, Bielka H, Rapoport TA. The signal sequence of nascent preprolactin interacts with the 54K polypeptide of the signal recognition particle. Nature. 320: 634-6. PMID 3010127 DOI: 10.1038/320634a0  1
1986 Rapoport TA. Protein translocation across and integration into membranes. Crc Critical Reviews in Biochemistry. 20: 73-137. PMID 3007024  1
1986 Wiedmann M, Huth A, Rapoport TA. A signal sequence is required for the functions of the signal recognition particle. Biochemical and Biophysical Research Communications. 134: 790-6. PMID 3004463 DOI: 10.1016/S0006-291X(86)80490-9  1
1986 Wiedmann M, Huth A, Rapoport TA. Internally transposed signal sequence of carp preproinsulin retains its functions with the signal recognition particle. Febs Letters. 194: 139-45. PMID 3000822 DOI: 10.1016/0014-5793(86)80065-5  1
1985 Rapoport TA. Extensions of the signal hypothesis--sequential insertion model versus amphipathic tunnel hypothesis. Febs Letters. 187: 1-10. PMID 3160605 DOI: 10.1016/0014-5793(85)81202-3  1
1985 Liebscher DH, Lipoldová M, Smrt J, Schwertner S, Wambutt R, Speter W, Pöhlmann C, Pfeifer M, Hahn V, Rapoport TA. Molecular cloning and identification of cDNA recombinants coding for bovine prochymosin in E. coli. Folia Biologica. 31: 81-92. PMID 2862065  1
1985 Rapoport TA, Wiedmann M. Chapter 1 Application of the Signal Hypothesis to the Incorporation of Integral Membrane Proteins Current Topics in Membranes and Transport. 24: 1-63. DOI: 10.1016/S0070-2161(08)60323-8  1
1985 Burns JA, Cornish-Bowden A, Groen AK, Heinrich R, Kacser H, Porteous JW, Rapoport SM, Rapoport TA, Stucki JW, Tager JM, Wanders RJA, Westerhoff HV. Control analysis of metabolic systems Trends in Biochemical Sciences. 10: 16. DOI: 10.1016/0968-0004(85)90008-8  1
1984 Wiedmann M, Huth A, Rapoport TA. Xenopus oocytes can secrete bacterial beta-lactamase. Nature. 309: 637-9. PMID 6374471 DOI: 10.1038/309637a0  1
1984 Hahn V, Winkler J, Rapoport TA, Liebscher DH, Coutelle C, Rosenthal S. Carp preproinsulin cDNA sequence and evolution of insulin genes. Folia Biologica. 30: 72-82. PMID 6373397 DOI: 10.1093/nar/11.13.4541  1
1984 Huth A, Rapoport TA, Kääriäinen L. Envelope proteins of Semliki Forest virus synthesized in Xenopus oocytes are transported to the cell surface. The Embo Journal. 3: 767-71. PMID 6373249  1
1984 Bassüner R, Wobus U, Rapoport TA. Signal recognition particle triggers the translocation of storage globulin polypeptides from field beans (Vicia faba L.) across mammalian endoplasmic reticulum membrane. Febs Letters. 166: 314-20. PMID 6198216 DOI: 10.1016/0014-5793(84)80103-9  1
1983 Bassüner R, Huth A, Manteuffel R, Rapoport TA. Secretion of plant storage globulin polypeptides by Xenopus laevis oocytes. European Journal of Biochemistry / Febs. 133: 321-6. PMID 6852043  1
1983 Finkelstein AV, Bendzko P, Rapoport TA. Recognition of signal sequences. Febs Letters. 161: 176-9. PMID 6617872 DOI: 10.1016/0014-5793(83)81002-3  1
1982 Bendzko P, Prehn S, Pfeil W, Rapoport TA. Different modes of membrane interactions of the signal sequence of carp preproinsulin and of the insertion sequence of rabbit cytochrome b5. European Journal of Biochemistry / Febs. 123: 121-6. PMID 7067693  1
1982 Huth A, Rapoport TA. Regulation of the biosynthesis of insulin in isolated Brockmann bodies of the carp (Cyprinus carpio). General and Comparative Endocrinology. 46: 158-67. PMID 7049828 DOI: 10.1016/0016-6480(82)90197-6  1
1982 Makower A, Dettmer R, Rapoport TA, Knospe S, Behlke J, Prehn S, Franke P, Etzold G, Rosenthal S. Carp insulin: amino acid sequence, biological activity and structural properties. European Journal of Biochemistry / Febs. 122: 339-45. PMID 7037403 DOI: 10.1111/j.1432-1033.1982.tb05886.x  1
1981 Rapoport TA. Intracellular compartmentation and secretion of carp proinsulin synthesized in Xenopus oocytes. European Journal of Biochemistry / Febs. 115: 665-9. PMID 7238527  1
1981 Huth A, Rapoport TA. Regulation of insulin biosynthesis in carp islets (Cyprinus carpio). Acta Biologica Et Medica Germanica. 40: 87-92. PMID 7020309  1
1981 Prehn S, Nürnberg P, Rapoport TA. A receptor for single segments of secretory proteins in rough endoplasmic reticulum membranes. Febs Letters. 123: 79-84. PMID 6258987 DOI: 10.1016/0014-5793(81)80024-5  1
1980 Heinrich R, Rapoport TA. Mathematical modelling of translation of mRNA in eucaryotes; steady state, time-dependent processes and application to reticulocytes. Journal of Theoretical Biology. 86: 279-313. PMID 7442295  1
1980 Rapoport TA, Prehn S, Tsamaloukas A, Coutelle C, Liebscher DH, Huth A, Rosenthal S. Biosynthesis of proinsulin of carp (Cyprinus carpio) and characterization and cloning of mRNA. Annals of the New York Academy of Sciences. 343: 111-32. PMID 6994550  1
1980 Liebscher DH, Coutelle C, Rapoport TA, Hahn V, Rosenthal S, Prehn S, Williamson R. Cloning of carp preproinsulin cDNA in the bacterial plasmid pBR322. Gene. 9: 233-46. PMID 6993287 DOI: 10.1016/0378-1119(90)90325-L  1
1980 Prehn S, Tsamaloukas A, Rapoport TA. Demonstration of specific receptors of the rough endoplasmic membrane for the signal sequence of carp preproinsulin. European Journal of Biochemistry / Febs. 107: 185-95. PMID 6249584  1
1979 Thiele BJ, Belkner J, Andree H, Rapoport TA, Rapoport SM. Synthesis of non-globin proteins in rabbit-erythroid cells. Synthesis of a lipoxygenase in reticulocytes. European Journal of Biochemistry / Febs. 96: 563-9. PMID 111926 DOI: 10.1111/j.1432-1033.1979.tb13070.x  1
1978 Rapoport TA, Thiele BJ, Prehn S, Marbaix G, Cleuter Y, Hubert E, Huez G. Synthesis of carp proinsulin in Xenopus oocytes. European Journal of Biochemistry / Febs. 87: 229-33. PMID 668692  0.72
1978 Rapoport TA, Kohnert KD, Knospe S, Lukowsky A, Prehn S, Schäfer H, Schmidt S, Ziegler M. Preparation and characterization of insulin of carp (Cyprinus carpio). Acta Biologica Et Medica Germanica. 37: 1153-60. PMID 373345  1
1978 Rapoport I, Rapoport TA, Rapoport SM. Analysis of pH-induced changes of the glycolysis of human erythrocytes. Acta Biologica Et Medica Germanica. 37: 393-401. PMID 32713  1
1977 Heinrich R, Rapoport SM, Rapoport TA. Metabolic regulation and mathematical models. Progress in Biophysics and Molecular Biology. 32: 1-82. PMID 343173 DOI: 10.1016/0079-6107(78)90017-2  1
1977 Rapoport TA, Otto M, Heinrich R. An extended model of the glycolysis in erythrocytes. Acta Biologica Et Medica Germanica. 36: 461-8. PMID 145774  1
1977 Schulz J, Baufeld A, Hofmann E, Rapoport TA, Heinrich R, Rapoport SM. Regulation of anaerobic glycolysis in Ehrlich ascites tumour cells. Acta Biologica Et Medica Germanica. 36: 1379-91. PMID 28629  1
1976 Rapoport TA, Klatt D, Prehn S, Hahn V, Höhne WE. Evidence for the synthesis of a precursor of carp proinsulin in a cell-free translation system. Febs Letters. 69: 32-6. PMID 791674  0.72
1976 Rapoport TA, Heinrich R, Rapoport SM. The regulatory principles of glycolysis in erythrocytes in vivo and in vitro. A minimal comprehensive model describing steady states, quasi-steady states and time-dependent processes. The Biochemical Journal. 154: 449-69. PMID 132930  1
1975 Rapoport TA, Heinrich R. Mathematical analysis of multienzyme systems. I. Modelling of the glycolysis of human erythrocytes. Bio Systems. 7: 120-9. PMID 168932  1
1975 Heinrich R, Rapoport TA. Mathematical analysis of multienzyme systems. II. Steady state and transient control. Bio Systems. 7: 130-6. PMID 125616  1
1974 Heinrich R, Rapoport TA. A linear steady-state treatment of enzymatic chains. Critique of the crossover theorem and a general procedure to identify interaction sites with an effector. European Journal of Biochemistry / Febs. 42: 97-105. PMID 4830199  1
1974 Heinrich R, Rapoport TA. A linear steady-state treatment of enzymatic chains. General properties, control and effector strength. European Journal of Biochemistry / Febs. 42: 89-95. PMID 4830198  1
1974 Rapoport TA, Prehn S, Lukowsky A, Junghahn I. Biosynthesis of proinsulin of carp (Cyprinus carpio). Acta Biologica Et Medica Germanica. 33: 953-61. PMID 4619956  0.72
1974 Lukowsky A, Prehn S, Rapoport TA. Biosynthesis of proinsulin in islets of Langerhans of the carp (Cyprinus carpio). Biochimica Et Biophysica Acta. 359: 248-52. PMID 4604163  0.72
1974 Rapoport TA, Heinrich R, Jacobasch G, Rapoport S. A linear steady-state treatment of enzymatic chains. A mathematical model of glycolysis of human erythrocytes. European Journal of Biochemistry / Febs. 42: 107-20. PMID 4364392  1
1973 Rapoport TA, Höhne WE, Heitmann P, Rapoport S. Binding of ligands to the inorganic pyrophosphatase of bakers' yeast. European Journal of Biochemistry / Febs. 33: 341-7. PMID 4348445  1
1973 Heinrich R, Rapoport TA. Linear theory of enzymatic chains; its application for the analysis of the crossover theorem and of the glycolysis of human erythrocytes. Acta Biologica Et Medica Germanica. 31: 479-94. PMID 4150081  1
1972 Rapoport TA, Höhne WE, Reich JG, Heitmann P, Rapoport SM. A kinetic model for the action of the inorganic pyrophosphatase from bakers' yeast. The activating influence of magnesium ions. European Journal of Biochemistry / Febs. 26: 237-46. PMID 4558242  1
Low-probability matches
2019 Twomey EC, Ji Z, Wales TE, Bodnar NO, Ficarro SB, Marto JA, Engen JR, Rapoport TA. Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding. Science (New York, N.Y.). PMID 31249135 DOI: 10.1126/science.aax1033  0.28
2018 Bodnar NO, Kim KH, Ji Z, Wales TE, Svetlov V, Nudler E, Engen JR, Walz T, Rapoport TA. Structure of the Cdc48 ATPase with its ubiquitin-binding cofactor Ufd1-Npl4. Nature Structural & Molecular Biology. PMID 29967539 DOI: 10.1038/s41594-018-0085-x  0.28
2017 Bodnar NO, Rapoport TA. Molecular Mechanism of Substrate Processing by the Cdc48 ATPase Complex. Cell. 169: 722-735.e9. PMID 28475898 DOI: 10.1016/j.cell.2017.04.020  0.28
2016 Chen Y, Seepersaud R, Bensing BA, Sullam PM, Rapoport TA. Mechanism of a cytosolic O-glycosyltransferase essential for the synthesis of a bacterial adhesion protein. Proceedings of the National Academy of Sciences of the United States of America. PMID 26884191 DOI: 10.1073/pnas.1600494113  0.24
1973 Höhne WE, Rapoport TA. Slow conformational changes of the inorganic pyrophosphatase from bakers' yeast induced by divalent metal ions. European Journal of Biochemistry / Febs. 33: 323-31. PMID 4348444  0.12
1983 Hahn V, Winkler J, Rapoport TA, Liebscher DH, Coutelle C, Rosenthal S. Carp preproinsulin cDNA sequence and evolution of insulin genes. Nucleic Acids Research. 11: 4541-52. PMID 6306593  0.12
2016 Baldridge RD, Rapoport TA. Autoubiquitination of the Hrd1 Ligase Triggers Protein Retrotranslocation in ERAD. Cell. PMID 27321670 DOI: 10.1016/j.cell.2016.05.048  0.01
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