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Reid Gilmore, Ph.D. - Publications

Biochemistry & Molecular Pharmacology University of Massachusetts Medical School, Worcester, MA, United States 

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Shrimal S, Cherepanova NA, Mandon EC, Venev SV, Gilmore R. Asparagine-linked glycosylation is not directly coupled to protein translocation across the endoplasmic reticulum in . Molecular Biology of the Cell. mbcE19060330. PMID 31433728 DOI: 10.1091/mbc.E19-06-0330  0.36
2018 Chang IJ, Byers HM, Ng BG, Merritt JL, Gilmore R, Shrimal S, Wei W, Zhang Y, Blair AB, Freeze HH, Zhang B, Lam C. Factor VIII and vWF deficiency in STT3A-CDG. Journal of Inherited Metabolic Disease. PMID 30701557 DOI: 10.1002/jimd.12021  0.36
2018 Shrimal S, Gilmore R. Oligosaccharyltransferase structures provide novel insight into the mechanism of asparagine-linked glycosylation in prokaryotic and eukaryotic cells. Glycobiology. PMID 30312397 DOI: 10.1093/glycob/cwy093  0.36
2018 Mandon EC, Butova C, Lachapelle A, Gilmore R. Conserved motifs on the cytoplasmic face of the protein translocation channel are critical for the transition between resting and active conformations. The Journal of Biological Chemistry. PMID 29986881 DOI: 10.1074/jbc.RA118.004123  0.36
2018 Braunger K, Pfeffer S, Shrimal S, Gilmore R, Berninghausen O, Mandon EC, Becker T, Förster F, Beckmann R. Structural basis for coupling protein transport and N-glycosylation at the mammalian endoplasmic reticulum. Science (New York, N.Y.). PMID 29519914 DOI: 10.1126/science.aar7899  0.36
2017 Shrimal S, Cherepanova NA, Gilmore R. One flexible loop in OST lassos both substrates. Nature Structural & Molecular Biology. 24: 1009-1010. PMID 29215637 DOI: 10.1038/nsmb.3508  0.36
2017 Shrimal S, Cherepanova NA, Gilmore R. DC2 and KCP2 mediate the interaction between the oligosaccharyltransferase and the ER translocon. The Journal of Cell Biology. PMID 28860277 DOI: 10.1083/jcb.201702159  0.36
2017 Tripathi A, Mandon EC, Gilmore R, Rapoport TA. Two alternative binding mechanisms connect the protein translocation Sec71/Sec72 complex with heat shock proteins. The Journal of Biological Chemistry. PMID 28286332 DOI: 10.1074/jbc.M116.761122  0.36
2016 Lopez-Sambrooks C, Shrimal S, Khodier C, Flaherty DP, Rinis N, Charest JC, Gao N, Zhao P, Wells L, Lewis TA, Lehrman MA, Gilmore R, Golden JE, Contessa JN. Oligosaccharyltransferase inhibition induces senescence in RTK-driven tumor cells. Nature Chemical Biology. PMID 27694802 DOI: 10.1038/nchembio.2194  1
2016 Cherepanova N, Shrimal S, Gilmore R. N-linked glycosylation and homeostasis of the endoplasmic reticulum. Current Opinion in Cell Biology. 41: 57-65. PMID 27085638 DOI: 10.1016/  0.36
2015 Shrimal S, Gilmore R. Reduced expression of the oligosaccharyltransferase exacerbates protein hypoglycosylation in cells lacking the fully assembled oligosaccharide donor. Glycobiology. 25: 774-83. PMID 25792706 DOI: 10.1093/glycob/cwv018  1
2015 Shrimal S, Cherepanova NA, Gilmore R. Cotranslational and posttranslocational N-glycosylation of proteins in the endoplasmic reticulum. Seminars in Cell & Developmental Biology. 41: 71-8. PMID 25460543 DOI: 10.1016/j.semcdb.2014.11.005  1
2014 Cherepanova NA, Shrimal S, Gilmore R. Oxidoreductase activity is necessary for N-glycosylation of cysteine-proximal acceptor sites in glycoproteins. The Journal of Cell Biology. 206: 525-39. PMID 25135935 DOI: 10.1083/jcb.201404083  1
2013 Shrimal S, Gilmore R. Glycosylation of closely spaced acceptor sites in human glycoproteins. Journal of Cell Science. 126: 5513-23. PMID 24105266 DOI: 10.1242/jcs.139584  1
2013 Shrimal S, Ng BG, Losfeld ME, Gilmore R, Freeze HH. Mutations in STT3A and STT3B cause two congenital disorders of glycosylation. Human Molecular Genetics. 22: 4638-45. PMID 23842455 DOI: 10.1093/hmg/ddt312  1
2013 Shrimal S, Trueman SF, Gilmore R. Extreme C-terminal sites are posttranslocationally glycosylated by the STT3B isoform of the OST. The Journal of Cell Biology. 201: 81-95. PMID 23530066 DOI: 10.1083/jcb.201301031  1
2013 Mandon EC, Trueman SF, Gilmore R. Protein translocation across the rough endoplasmic reticulum. Cold Spring Harbor Perspectives in Biology. 5. PMID 23251026 DOI: 10.1101/cshperspect.a013342  1
2012 Trueman SF, Mandon EC, Gilmore R. A gating motif in the translocation channel sets the hydrophobicity threshold for signal sequence function. The Journal of Cell Biology. 199: 907-18. PMID 23229898 DOI: 10.1083/jcb.201207163  1
2012 Gilmore R, Mandon EC. Understanding integration of α-helical membrane proteins: the next steps. Trends in Biochemical Sciences. 37: 303-8. PMID 22748693 DOI: 10.1016/j.tibs.2012.05.003  1
2012 Zhang X, Garbett K, Veeraraghavalu K, Wilburn B, Gilmore R, Mirnics K, Sisodia SS. A role for presenilins in autophagy revisited: normal acidification of lysosomes in cells lacking PSEN1 and PSEN2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 8633-48. PMID 22723704 DOI: 10.1523/JNEUROSCI.0556-12.2012  1
2011 Trueman SF, Mandon EC, Gilmore R. Translocation channel gating kinetics balances protein translocation efficiency with signal sequence recognition fidelity. Molecular Biology of the Cell. 22: 2983-93. PMID 21737680 DOI: 10.1091/mbc.E11-01-0070  1
2011 Gilmore R. Structural biology: Porthole to catalysis. Nature. 474: 292-3. PMID 21677742 DOI: 10.1038/474292a  1
2011 Bas T, Gao GY, Lvov A, Chandrasekhar KD, Gilmore R, Kobertz WR. Post-translational N-glycosylation of type I transmembrane KCNE1 peptides: implications for membrane protein biogenesis and disease. The Journal of Biological Chemistry. 286: 28150-9. PMID 21676880 DOI: 10.1074/jbc.M111.235168  1
2009 Becker T, Bhushan S, Jarasch A, Armache JP, Funes S, Jossinet F, Gumbart J, Mielke T, Berninghausen O, Schulten K, Westhof E, Gilmore R, Mandon EC, Beckmann R. Structure of monomeric yeast and mammalian Sec61 complexes interacting with the translating ribosome. Science (New York, N.Y.). 326: 1369-73. PMID 19933108 DOI: 10.1126/science.1178535  1
2009 Mandon EC, Trueman SF, Gilmore R. Translocation of proteins through the Sec61 and SecYEG channels. Current Opinion in Cell Biology. 21: 501-7. PMID 19450960 DOI: 10.1016/  1
2009 Ruiz-Canada C, Kelleher DJ, Gilmore R. Cotranslational and posttranslational N-glycosylation of polypeptides by distinct mammalian OST isoforms. Cell. 136: 272-83. PMID 19167329 DOI: 10.1016/j.cell.2008.11.047  1
2008 Magnelli P, Cipollo JF, Ratner DM, Cui J, Kelleher D, Gilmore R, Costello CE, Robbins PW, Samuelson J. Unique Asn-linked oligosaccharides of the human pathogen Entamoeba histolytica. The Journal of Biological Chemistry. 283: 18355-64. PMID 18417475 DOI: 10.1074/jbc.M800725200  1
2008 Jiang Y, Cheng Z, Mandon EC, Gilmore R. An interaction between the SRP receptor and the translocon is critical during cotranslational protein translocation. The Journal of Cell Biology. 180: 1149-61. PMID 18347066 DOI: 10.1083/jcb.200707196  1
2007 Banerjee S, Vishwanath P, Cui J, Kelleher DJ, Gilmore R, Robbins PW, Samuelson J. The evolution of N-glycan-dependent endoplasmic reticulum quality control factors for glycoprotein folding and degradation. Proceedings of the National Academy of Sciences of the United States of America. 104: 11676-81. PMID 17606910 DOI: 10.1073/pnas.0704862104  1
2007 Kelleher DJ, Banerjee S, Cura AJ, Samuelson J, Gilmore R. Dolichol-linked oligosaccharide selection by the oligosaccharyltransferase in protist and fungal organisms. The Journal of Cell Biology. 177: 29-37. PMID 17403929 DOI: 10.1083/jcb.200611079  1
2007 Mandon EC, Gilmore R. The tail end of membrane insertion. Cell. 128: 1031-2. PMID 17382875 DOI: 10.1016/j.cell.2007.03.001  0.36
2005 Karamyshev AL, Kelleher DJ, Gilmore R, Johnson AE, von Heijne G, Nilsson I. Mapping the interaction of the STT3 subunit of the oligosaccharyl transferase complex with nascent polypeptide chains. The Journal of Biological Chemistry. 280: 40489-93. PMID 16216884 DOI: 10.1074/jbc.M509168200  1
2005 Samuelson J, Banerjee S, Magnelli P, Cui J, Kelleher DJ, Gilmore R, Robbins PW. The diversity of dolichol-linked precursors to Asn-linked glycans likely results from secondary loss of sets glycosyltranferases Proceedings of the National Academy of Sciences of the United States of America. 102: 1548-1553. PMID 15665075 DOI: 10.1073/pnas.0409460102  1
2005 Cheng Z, Jiang Y, Mandon EC, Gilmore R. Identification of cytoplasmic residues of Sec61p involved in ribosome binding and cotranslational translocation. The Journal of Cell Biology. 168: 67-77. PMID 15631991 DOI: 10.1083/jcb.200408188  0.36
2004 Mandon EC, Gilmore R. GTPase twins in the SRP family. Nature Structural & Molecular Biology. 11: 115-6. PMID 14749771 DOI: 10.1038/nsmb0204-115  0.36
2003 Mandon EC, Jiang Y, Gilmore R. Dual recognition of the ribosome and the signal recognition particle by the SRP receptor during protein targeting to the endoplasmic reticulum. The Journal of Cell Biology. 162: 575-85. PMID 12913112 DOI: 10.1083/jcb.200303143  0.36
2003 Kelleher DJ, Karaoglu D, Mandon EC, Gilmore R. Oligosaccharyltransferase isoforms that contain different catalytic STT3 subunits have distinct enzymatic properties. Molecular Cell. 12: 101-11. PMID 12887896  0.36
2003 Wu X, Rush JS, Karaoglu D, Krasnewich D, Lubinsky MS, Waechter CJ, Gilmore R, Freeze HH. Deficiency of UDP-GlcNAc:Dolichol Phosphate N-Acetylglucosamine-1 Phosphate Transferase (DPAGT1) causes a novel congenital disorder of Glycosylation Type Ij. Human Mutation. 22: 144-50. PMID 12872255 DOI: 10.1002/humu.10239  1
2003 Nilsson I, Kelleher DJ, Miao Y, Shao Y, Kreibich G, Gilmore R, von Heijne G, Johnson AE. Photocross-linking of nascent chains to the STT3 subunit of the oligosaccharyltransferase complex. The Journal of Cell Biology. 161: 715-25. PMID 12756234 DOI: 10.1083/jcb.200301043  1
1986 Evans EA, Gilmore R, Blobel G. Purification of microsomal signal peptidase as a complex. Proceedings of the National Academy of Sciences of the United States of America. 83: 581-5. PMID 3511473  1
1985 Gilmore R, Blobel G. Translocation of secretory proteins across the microsomal membrane occurs through an environment accessible to aqueous perturbants. Cell. 42: 497-505. PMID 2992801 DOI: 10.1016/0092-8674(85)90107-2  1
1984 Blobel G, Walter P, Gilmore R. Intracellular protein topogenesis. Progress in Clinical and Biological Research. 168: 3-10. PMID 6514738  1
1984 Walter P, Gilmore R, Blobel G. Protein translocation across the endoplasmic reticulum. Cell. 38: 5-8. PMID 6088076  1
1983 Gilmore R, Blobel G. Transient involvement of signal recognition particle and its receptor in the microsomal membrane prior to protein translocation. Cell. 35: 677-85. PMID 6317198 DOI: 10.1016/0092-8674(83)90100-9  1
1982 Gilmore R, Walter P, Blobel G. Protein translocation across the endoplasmic reticulum. II. Isolation and characterization of the signal recognition particle receptor. The Journal of Cell Biology. 95: 470-7. PMID 6292236  1
1982 Gilmore R, Blobel G, Walter P. Protein translocation across the endoplasmic reticulum. I. Detection in the microsomal membrane of a receptor for the signal recognition particle. The Journal of Cell Biology. 95: 463-9. PMID 6292235  1
1982 Walter P, Gilmore R, Müller M, Blobel G. The protein translocation machinery of the endoplasmic reticulum. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 300: 225-8. PMID 6131460  1
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