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Ron D. Vale - Publications

University of California, San Francisco, San Francisco, CA 

249 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Skokan TD, Vale RD, McKinley KL. Cell Sorting in Hydra vulgaris Arises from Differing Capacities for Epithelialization between Cell Types. Current Biology : Cb. PMID 32795440 DOI: 10.1016/J.Cub.2020.07.035  0.767
2020 Morrissey MA, Kern N, Vale RD. CD47 Ligation Repositions the Inhibitory Receptor SIRPA to Suppress Integrin Activation and Phagocytosis. Immunity. PMID 32768386 DOI: 10.1016/J.Immuni.2020.07.008  0.754
2020 Niekamp S, Stuurman N, Vale RD. A 6-nm ultra-photostable DNA FluoroCube for fluorescence imaging. Nature Methods. PMID 32203385 DOI: 10.1038/S41592-020-0782-3  0.305
2020 Greenan GA, Vale RD, Agard DA. Electron cryotomography of intact motile cilia defines the basal body to axoneme transition. The Journal of Cell Biology. 219. PMID 31874113 DOI: 10.1083/Jcb.201907060  0.421
2019 Niekamp S, Coudray N, Zhang N, Vale RD, Bhabha G. Coupling of ATPase activity, microtubule binding, and mechanics in the dynein motor domain. The Embo Journal. 38: e101414. PMID 31268607 DOI: 10.15252/Embj.2018101414  0.485
2019 Ditlev JA, Vega AR, Köster DV, Su X, Tani T, Lakoduk AM, Vale RD, Mayor S, Jaqaman K, Rosen MK. A composition-dependent molecular clutch between T cell signaling condensates and actin. Elife. 8. PMID 31268421 DOI: 10.7554/Elife.42695  0.374
2019 Niekamp S, Coudray N, Zhang N, Vale RD, Bhabha G. Coupling of ATPase activity, microtubule binding, and mechanics in the dynein motor domain. The Embo Journal. PMID 31152008 DOI: 10.15252/embj.2018101414  0.383
2019 Wang Y, Huynh W, Skokan TD, Lu W, Weiss A, Vale RD. CRACR2a is a calcium-activated dynein adaptor protein that regulates endocytic traffic. The Journal of Cell Biology. PMID 30814157 DOI: 10.1083/Jcb.201806097  0.446
2019 Niekamp S, Sung J, Huynh W, Bhabha G, Vale RD, Stuurman N. Nanometer-accuracy distance measurements between fluorophores at the single-molecule level. Proceedings of the National Academy of Sciences of the United States of America. PMID 30770448 DOI: 10.1073/Pnas.1815826116  0.305
2019 Gibbons WE, Vale RD, Sale WS. Ian Read Gibbons. 30 October 1931—30 January 2018 Biographical Memoirs of Fellows of the Royal Society. 66: 201-223. DOI: 10.1098/Rsbm.2018.0034  0.392
2018 Williamson AP, Vale RD. Spatial control of Draper receptor signaling initiates apoptotic cell engulfment. The Journal of Cell Biology. PMID 30139739 DOI: 10.1083/Jcb.201711175  0.587
2018 Greenan GA, Keszthelyi B, Vale RD, Agard DA. Insights into centriole geometry revealed by cryoTomography of doublet and triplet centrioles. Elife. 7. PMID 30080137 DOI: 10.7554/Elife.36851  0.372
2018 McKinley KL, Stuurman N, Royer LA, Schartner C, Castillo-Azofeifa D, Delling M, Klein OD, Vale RD. Cellular aspect ratio and cell division mechanics underlie the patterning of cell progeny in diverse mammalian epithelia. Elife. 7. PMID 29897330 DOI: 10.7554/Elife.36739  0.776
2018 Morrissey MA, Williamson AP, Steinbach AM, Roberts EW, Kern N, Headley MB, Vale R. Chimeric antigen receptors that trigger phagocytosis. Elife. 7. PMID 29862966 DOI: 10.7554/Elife.36688  0.775
2018 Reck-Peterson SL, Redwine WB, Vale RD, Carter AP. Publisher Correction: The cytoplasmic dynein transport machinery and its many cargoes. Nature Reviews. Molecular Cell Biology. PMID 29740130 DOI: 10.1038/S41580-018-0021-2  0.676
2018 Reck-Peterson SL, Redwine WB, Vale RD, Carter AP. The cytoplasmic dynein transport machinery and its many cargoes. Nature Reviews. Molecular Cell Biology. PMID 29662141 DOI: 10.1038/S41580-018-0004-3  0.778
2018 McKinley KL, Stuurman N, Royer LA, Schartner C, Castillo-Azofeifa D, Delling M, Klein OD, Vale RD. Author response: Cellular aspect ratio and cell division mechanics underlie the patterning of cell progeny in diverse mammalian epithelia Elife. DOI: 10.7554/Elife.36739.037  0.767
2018 Morrissey MA, Williamson AP, Steinbach AM, Roberts EW, Kern N, Headley MB, Vale RD. Author response: Chimeric antigen receptors that trigger phagocytosis Elife. DOI: 10.7554/Elife.36688.022  0.735
2018 Vega A, Ditlev J, Koster D, Su X, Vale R, Mayor S, Rosen MK, Jaqaman K. Differential LAT Microcluster Composition and ACTIN-Dependent Movement at the Immunological Synapse Center Biophysical Journal. 114: 201a. DOI: 10.1016/J.Bpj.2017.11.1123  0.307
2017 Carbone CB, Kern N, Fernandes RA, Hui E, Su X, Garcia KC, Vale RD. In vitro reconstitution of T cell receptor-mediated segregation of the CD45 phosphatase. Proceedings of the National Academy of Sciences of the United States of America. PMID 29042512 DOI: 10.1073/Pnas.1710358114  0.504
2017 Huynh W, Vale RD. Disease-associated mutations in human BICD2 hyperactivate motility of dynein-dynactin. The Journal of Cell Biology. PMID 28883039 DOI: 10.1083/Jcb.201703201  0.333
2017 Hui E, Cheung J, Zhu J, Su X, Taylor MJ, Wallweber HA, Sasmal DK, Huang J, Kim JM, Mellman I, Vale RD. T cell costimulatory receptor CD28 is a primary target for PD-1-mediated inhibition. Science (New York, N.Y.). PMID 28280247 DOI: 10.1126/Science.Aaf1292  0.448
2017 Su X, Ditlev JA, Rosen MK, Vale RD. Reconstitution of TCR Signaling Using Supported Lipid Bilayers. Methods in Molecular Biology (Clifton, N.J.). 1584: 65-76. PMID 28255696 DOI: 10.1007/978-1-4939-6881-7_5  0.338
2017 Niekamp S, Stuurman N, Zhang N, Vale RD. Tracking Dynein Stepping along Microtubules using Multi-Color High Resolution Imaging Biophysical Journal. 112: 261a. DOI: 10.1016/J.Bpj.2016.11.1419  0.405
2016 Schroeder CM, Vale RD. Assembly and activation of dynein-dynactin by the cargo adaptor protein Hook3. The Journal of Cell Biology. 214: 309-18. PMID 27482052 DOI: 10.1083/Jcb.201604002  0.453
2016 Yan X, Hoek TA, Vale RD, Tanenbaum ME. Dynamics of Translation of Single mRNA Molecules In Vivo. Cell. 165: 976-89. PMID 27153498 DOI: 10.1016/J.Cell.2016.04.034  0.671
2016 Ori-McKenney KM, McKenney RJ, Huang HH, Li T, Meltzer S, Jan LY, Vale RD, Wiita AP, Jan YN. Phosphorylation of β-Tubulin by the Down Syndrome Kinase, Minibrain/DYRK1a, Regulates Microtubule Dynamics and Dendrite Morphogenesis. Neuron. PMID 27112495 DOI: 10.1016/J.Neuron.2016.03.027  0.317
2016 Su X, Ditlev JA, Hui E, Xing W, Banjade S, Okrut J, King DS, Taunton J, Rosen MK, Vale RD. Phase separation of signaling molecules promotes T cell receptor signal transduction. Science (New York, N.Y.). PMID 27056844 DOI: 10.1126/Science.Aad9964  0.513
2016 McKenney RJ, Huynh W, Vale RD, Sirajuddin M. Tyrosination of α-tubulin controls the initiation of processive dynein-dynactin motility. The Embo Journal. PMID 26968983 DOI: 10.15252/Embj.201593071  0.46
2016 Williamson A, Vale R. Abstract A165: Engineering approaches to uncover the mechanism of apoptotic cell clearance by a conserved signaling system Cancer Immunology Research. 4. DOI: 10.1158/2326-6074.Cricimteatiaacr15-A165  0.312
2016 Su X, Ditlev J, Hui E, Banjade S, Okrut J, Taunton J, Rosen M, Vale R. Abstract A087: Phase separation of signaling molecules promotes T cell receptor signal transduction Cancer Immunology Research. 4. DOI: 10.1158/2326-6074.Cricimteatiaacr15-A087  0.518
2016 Su X, Ditlev J, Hui E, Rosen M, Vale R. Abstract B101: Mechanism of T cell activation by phase separation Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-B101  0.519
2015 Bhabha G, Johnson GT, Schroeder CM, Vale RD. How Dynein Moves Along Microtubules. Trends in Biochemical Sciences. PMID 26678005 DOI: 10.1016/J.Tibs.2015.11.004  0.503
2015 Yildiz A, Vale RD. Total Internal Reflection Fluorescence Microscopy. Cold Spring Harbor Protocols. 2015: pdb.top086348. PMID 26330632 DOI: 10.1101/Pdb.Top086348  0.31
2015 Yildiz A, Vale RD. Tracking Movements of the Microtubule Motors Kinesin and Dynein Using Total Internal Reflection Fluorescence Microscopy. Cold Spring Harbor Protocols. 2015: pdb.prot086355. PMID 26330626 DOI: 10.1101/Pdb.Prot086355  0.43
2015 Jonsson E, Yamada M, Vale RD, Goshima G. Clustering of a kinesin-14 motor enables processive retrograde microtubule-based transport in plants. Nature Plants. 1. PMID 26322239 DOI: 10.1038/Nplants.2015.87  0.478
2015 Petry S, Vale RD. Microtubule nucleation at the centrosome and beyond. Nature Cell Biology. 17: 1089-93. PMID 26316453 DOI: 10.1038/Ncb3220  0.397
2015 Tanenbaum ME, Stern-Ginossar N, Weissman JS, Vale RD. Regulation of mRNA translation during mitosis. Elife. 4. PMID 26305499 DOI: 10.7554/Elife.07957  0.67
2015 Esmaeeli Nieh S, Madou MR, Sirajuddin M, Fregeau B, McKnight D, Lexa K, Strober J, Spaeth C, Hallinan BE, Smaoui N, Pappas JG, Burrow TA, McDonald MT, Latibashvili M, Leshinsky-Silver E, ... Vale RD, et al. De novo mutations in KIF1A cause progressive encephalopathy and brain atrophy. Annals of Clinical and Translational Neurology. 2: 623-35. PMID 26125038 DOI: 10.1002/Acn3.198  0.343
2015 Ham H, Huynh W, Schoon RA, Vale RD, Billadeau DD. HkRP3 is a microtubule-binding protein regulating lytic granule clustering and NK cell killing. Journal of Immunology (Baltimore, Md. : 1950). 194: 3984-96. PMID 25762780 DOI: 10.4049/Jimmunol.1402897  0.42
2015 Tanenbaum ME, Stern-Ginossar N, Weissman JS, Vale RD. Author response: Regulation of mRNA translation during mitosis Elife. DOI: 10.7554/Elife.07957.018  0.641
2015 Gilbert LA, Tanenbaum ME, Horlbeck MA, Adamson B, Villalta JE, Vale RD, Kampmann M, Weissman JS. Abstract PR05: Using genome-scale CRISPR-mediated loss-of-function and gain-of-function screens to analyze gene-drug interactions in cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Transcagen-Pr05  0.643
2015 McKenney RJ, Huynh W, Siarjuddin M, Tanenbaum M, Bhabha G, Vale RD. Multiplex Regulation of Cytoplasmic Dynein Motility Biophysical Journal. 108: 9a. DOI: 10.1016/J.Bpj.2014.11.072  0.763
2014 Bhabha G, Cheng HC, Zhang N, Moeller A, Liao M, Speir JA, Cheng Y, Vale RD. Allosteric communication in the dynein motor domain. Cell. 159: 857-68. PMID 25417161 DOI: 10.1016/J.Cell.2014.10.018  0.464
2014 Tanenbaum ME, Gilbert LA, Qi LS, Weissman JS, Vale RD. A protein-tagging system for signal amplification in gene expression and fluorescence imaging. Cell. 159: 635-46. PMID 25307933 DOI: 10.1016/J.Cell.2014.09.039  0.678
2014 Ribeiro SA, D'Ambrosio MV, Vale RD. Induction of focal adhesions and motility in Drosophila S2 cells. Molecular Biology of the Cell. 25: 3861-9. PMID 25273555 DOI: 10.1091/Mbc.E14-04-0863  0.63
2014 Schroeder CM, Ostrem JM, Hertz NT, Vale RD. A Ras-like domain in the light intermediate chain bridges the dynein motor to a cargo-binding region. Elife. 3: e03351. PMID 25272277 DOI: 10.7554/Elife.03351  0.441
2014 McKenney RJ, Huynh W, Tanenbaum ME, Bhabha G, Vale RD. Activation of cytoplasmic dynein motility by dynactin-cargo adapter complexes. Science (New York, N.Y.). 345: 337-41. PMID 25035494 DOI: 10.1126/Science.1254198  0.763
2014 Hendershott MC, Vale RD. Regulation of microtubule minus-end dynamics by CAMSAPs and Patronin. Proceedings of the National Academy of Sciences of the United States of America. 111: 5860-5. PMID 24706919 DOI: 10.1073/Pnas.1404133111  0.754
2014 Sirajuddin M, Rice LM, Vale RD. Regulation of microtubule motors by tubulin isotypes and post-translational modifications. Nature Cell Biology. 16: 335-44. PMID 24633327 DOI: 10.1038/Ncb2920  0.493
2014 Vale RD. Preface: the role of reconstitution in cytoskeleton research. Methods in Enzymology. 540: xix-xxiii. PMID 24630122 DOI: 10.1016/B978-0-12-397924-7.09985-4  0.469
2014 Hui E, Vale RD. In vitro membrane reconstitution of the T-cell receptor proximal signaling network. Nature Structural & Molecular Biology. 21: 133-42. PMID 24463463 DOI: 10.1038/Nsmb.2762  0.484
2014 Toret CP, D'Ambrosio MV, Vale RD, Simon MA, Nelson WJ. A genome-wide screen identifies conserved protein hubs required for cadherin-mediated cell-cell adhesion. The Journal of Cell Biology. 204: 265-79. PMID 24446484 DOI: 10.1083/Jcb.201306082  0.633
2014 Schroeder CM, Ostrem JM, Hertz NT, Vale RD. Author response: A Ras-like domain in the light intermediate chain bridges the dynein motor to a cargo-binding region Elife. DOI: 10.7554/Elife.03351.021  0.38
2014 Jonsson E, Vale RD. The Kinesin-1 Gating Mechanism Studied by Pre-Steady State Kinetics Biophysical Journal. 106: 781a. DOI: 10.1016/J.Bpj.2013.11.4281  0.447
2014 McKenney RJ, Tanenbaum ME, Bhabha G, Vale RD. BicD2 and Dynactin Convert a Non-Processive Cytoplasmic Dynein to an Ultra-Processive Directional Motor Biophysical Journal. 106: 353a. DOI: 10.1016/J.Bpj.2013.11.2009  0.758
2014 Schroeder CM, Vale RD. A Structural and Functional Analysis of the Dynein Light Intermediate Chain Biophysical Journal. 106: 352a-353a. DOI: 10.1016/J.Bpj.2013.11.2005  0.451
2014 Cheng H, Bhabha G, Vale RD. Crystal and EM Structures Reveal a Mechanism for Long-Range Allosteric Communication in the Yeast Dynein Motor Domain Biophysical Journal. 106: 352a. DOI: 10.1016/J.Bpj.2013.11.2001  0.473
2014 Vale R, Cheng H, Bhabha G, McKenney R, Tanenbaum M, Schroeder C. Mechanisms of Dynein-Driven Microtubule Sliding and Cargo Transport Biophysical Journal. 106: 10a. DOI: 10.1016/J.Bpj.2013.11.105  0.776
2013 Moutinho-Pereira S, Stuurman N, Afonso O, Hornsveld M, Aguiar P, Goshima G, Vale RD, Maiato H. Genes involved in centrosome-independent mitotic spindle assembly in Drosophila S2 cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 19808-13. PMID 24255106 DOI: 10.1073/Pnas.1320013110  0.369
2013 Tanenbaum ME, Vale RD, McKenney RJ. Cytoplasmic dynein crosslinks and slides anti-parallel microtubules using its two motor domains. Elife. 2: e00943. PMID 24015359 DOI: 10.7554/Elife.00943  0.777
2013 Petry S, Groen AC, Ishihara K, Mitchison TJ, Vale RD. Branching microtubule nucleation in Xenopus egg extracts mediated by augmin and TPX2. Cell. 152: 768-77. PMID 23415226 DOI: 10.1016/J.Cell.2012.12.044  0.42
2013 Tanenbaum ME, Vale RD, McKenney RJ. Author response: Cytoplasmic dynein crosslinks and slides anti-parallel microtubules using its two motor domains Elife. DOI: 10.7554/Elife.00943.020  0.741
2013 Niitani Y, Jonsson E, Vale RD, Tomishige M. 2P171 Strain-dependent regulation of the kinesin-1's catalytic activity as studied by disulfide-crosslinking of the neck linker(11. Molecular motor,Poster) Seibutsu Butsuri. 53: S187. DOI: 10.2142/Biophys.53.S187_3  0.389
2012 James JR, Vale RD. Biophysical mechanism of T-cell receptor triggering in a reconstituted system. Nature. 487: 64-9. PMID 22763440 DOI: 10.1038/Nature11220  0.332
2012 Zou W, Wang X, Vale RD, Ou G. Autophagy genes promote apoptotic cell corpse clearance. Autophagy. 8: 1267-8. PMID 22653037 DOI: 10.4161/Auto.20786  0.529
2012 Li W, Zou W, Yang Y, Chai Y, Chen B, Cheng S, Tian D, Wang X, Vale RD, Ou G. Autophagy genes function sequentially to promote apoptotic cell corpse degradation in the engulfing cell. The Journal of Cell Biology. 197: 27-35. PMID 22451698 DOI: 10.1083/Jcb.201111053  0.52
2012 Laan L, Pavin N, Husson J, Romet-Lemonne G, van Duijn M, López MP, Vale RD, Jülicher F, Reck-Peterson SL, Dogterom M. Cortical dynein controls microtubule dynamics to generate pulling forces that position microtubule asters. Cell. 148: 502-14. PMID 22304918 DOI: 10.1016/J.Cell.2012.01.007  0.696
2012 Cho C, Vale RD. The mechanism of dynein motility: insight from crystal structures of the motor domain. Biochimica Et Biophysica Acta. 1823: 182-91. PMID 22062687 DOI: 10.1016/J.Bbamcr.2011.10.009  0.687
2012 Sheetz M, Spudich J, Vale R. The lasker awards: Motors take centre stage Nature Cell Biology. 14: 1113. DOI: 10.1038/Ncb2618  0.719
2011 Petry S, Vale RD. A new cap for kinetochore fibre minus ends. Nature Cell Biology. 13: 1389-91. PMID 22081093 DOI: 10.1038/Ncb2387  0.389
2011 Petry S, Pugieux C, Nédélec FJ, Vale RD. Augmin promotes meiotic spindle formation and bipolarity in Xenopus egg extracts. Proceedings of the National Academy of Sciences of the United States of America. 108: 14473-8. PMID 21844347 DOI: 10.1073/Pnas.1110412108  0.381
2011 Singhvi A, Teuliere J, Talavera K, Cordes S, Ou G, Vale RD, Prasad BC, Clark SG, Garriga G. The Arf GAP CNT-2 regulates the apoptotic fate in C. elegans asymmetric neuroblast divisions. Current Biology : Cb. 21: 948-54. PMID 21596567 DOI: 10.1016/J.Cub.2011.04.025  0.566
2011 Carter AP, Cho C, Jin L, Vale RD. Crystal structure of the dynein motor domain. Science (New York, N.Y.). 331: 1159-65. PMID 21330489 DOI: 10.1126/Science.1202393  0.731
2011 Huckaba TM, Gennerich A, Wilhelm JE, Chishti AH, Vale RD. Kinesin-73 is a processive motor that localizes to Rab5-containing organelles. The Journal of Biological Chemistry. 286: 7457-67. PMID 21169635 DOI: 10.1074/Jbc.M110.167023  0.841
2010 D'Ambrosio MV, Vale RD. A whole genome RNAi screen of Drosophila S2 cell spreading performed using automated computational image analysis. The Journal of Cell Biology. 191: 471-8. PMID 21041442 DOI: 10.1083/Jcb.201003135  0.586
2010 Goodwin SS, Vale RD. Patronin regulates the microtubule network by protecting microtubule minus ends. Cell. 143: 263-74. PMID 20946984 DOI: 10.1016/J.Cell.2010.09.022  0.665
2010 Ou G, Stuurman N, D'Ambrosio M, Vale RD. Polarized myosin produces unequal-size daughters during asymmetric cell division. Science (New York, N.Y.). 330: 677-80. PMID 20929735 DOI: 10.1126/Science.1196112  0.695
2010 Yu CH, Wu HJ, Kaizuka Y, Vale RD, Groves JT. Altered actin centripetal retrograde flow in physically restricted immunological synapses. Plos One. 5: e11878. PMID 20686692 DOI: 10.1371/Journal.Pone.0011878  0.31
2010 Uehara R, Goshima G, Mabuchi I, Vale RD, Spudich JA, Griffis ER. Determinants of myosin II cortical localization during cytokinesis. Current Biology : Cb. 20: 1080-5. PMID 20541410 DOI: 10.1016/J.Cub.2010.04.058  0.602
2010 Carter AP, Vale RD. Communication between the AAA+ ring and microtubule-binding domain of dynein. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 88: 15-21. PMID 20130675 DOI: 10.1139/o09-127  0.548
2010 Huang J, Kardon J, Cho C, Vale R, Reck-Peterson S. Mechanism and Regulation of Cytoplasmic Dynein Biophysical Journal. 98: 620a. DOI: 10.1016/J.Bpj.2009.12.3395  0.829
2009 Kardon JR, Vale RD. Regulators of the cytoplasmic dynein motor. Nature Reviews. Molecular Cell Biology. 10: 854-65. PMID 19935668 DOI: 10.1038/Nrm2804  0.83
2009 Vale RD, Spudich JA, Griffis ER. Dynamics of myosin, microtubules, and Kinesin-6 at the cortex during cytokinesis in Drosophila S2 cells. The Journal of Cell Biology. 186: 727-38. PMID 19720876 DOI: 10.1083/Jcb.200902083  0.605
2009 Kaizuka Y, Douglass AD, Vardhana S, Dustin ML, Vale RD. The coreceptor CD2 uses plasma membrane microdomains to transduce signals in T cells. The Journal of Cell Biology. 185: 521-34. PMID 19398758 DOI: 10.1083/Jcb.200809136  0.724
2009 Uehara R, Nozawa RS, Tomioka A, Petry S, Vale RD, Obuse C, Goshima G. The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells. Proceedings of the National Academy of Sciences of the United States of America. 106: 6998-7003. PMID 19369198 DOI: 10.1073/Pnas.0901587106  0.389
2009 Ou G, Vale RD. Molecular signatures of cell migration in C. elegans Q neuroblasts. The Journal of Cell Biology. 185: 77-85. PMID 19349580 DOI: 10.1083/Jcb.200812077  0.537
2009 Kardon JR, Reck-Peterson SL, Vale RD. Regulation of the processivity and intracellular localization of Saccharomyces cerevisiae dynein by dynactin. Proceedings of the National Academy of Sciences of the United States of America. 106: 5669-74. PMID 19293377 DOI: 10.1073/Pnas.0900976106  0.842
2009 Gennerich A, Vale RD. Walking the walk: how kinesin and dynein coordinate their steps. Current Opinion in Cell Biology. 21: 59-67. PMID 19179063 DOI: 10.1016/J.Ceb.2008.12.002  0.506
2009 Laan L, Husson J, van Duijn M, Vale RD, Reck-Peterson SL, Dogterom M. “Cortical” Dynein Can Capture And Pull On Dynamic Microtubule Ends In Vitro Biophysical Journal. 96: 572a. DOI: 10.1016/J.Bpj.2008.12.3745  0.692
2008 Carter AP, Garbarino JE, Wilson-Kubalek EM, Shipley WE, Cho C, Milligan RA, Vale RD, Gibbons IR. Structure and functional role of dynein's microtubule-binding domain. Science (New York, N.Y.). 322: 1691-5. PMID 19074350 DOI: 10.1126/Science.1164424  0.711
2008 Yildiz A, Tomishige M, Gennerich A, Vale RD. Intramolecular strain coordinates kinesin stepping behavior along microtubules. Cell. 134: 1030-41. PMID 18805095 DOI: 10.1016/J.Cell.2008.07.018  0.476
2008 Cho C, Reck-Peterson SL, Vale RD. Regulatory ATPase sites of cytoplasmic dynein affect processivity and force generation. The Journal of Biological Chemistry. 283: 25839-45. PMID 18650442 DOI: 10.1074/Jbc.M802951200  0.758
2008 Goshima G, Mayer M, Zhang N, Stuurman N, Vale RD. Augmin: a protein complex required for centrosome-independent microtubule generation within the spindle. The Journal of Cell Biology. 181: 421-9. PMID 18443220 DOI: 10.1083/Jcb.200711053  0.402
2008 Trammell MA, Mahoney NM, Agard DA, Vale RD. Mob4 plays a role in spindle focusing in Drosophila S2 cells. Journal of Cell Science. 121: 1284-92. PMID 18388316 DOI: 10.1242/Jcs.017210  0.37
2008 Roll-Mecak A, Vale RD. Structural basis of microtubule severing by the hereditary spastic paraplegia protein spastin. Nature. 451: 363-7. PMID 18202664 DOI: 10.1038/Nature06482  0.401
2008 Douglass AD, Vale RD. Single-molecule imaging of fluorescent proteins. Methods in Cell Biology. 85: 113-25. PMID 18155461 DOI: 10.1016/S0091-679X(08)85006-6  0.728
2007 Kaizuka Y, Douglass AD, Varma R, Dustin ML, Vale RD. Mechanisms for segregating T cell receptor and adhesion molecules during immunological synapse formation in Jurkat T cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 20296-301. PMID 18077330 DOI: 10.1073/Pnas.0710258105  0.741
2007 Gennerich A, Carter AP, Reck-Peterson SL, Vale RD. Force-induced bidirectional stepping of cytoplasmic dynein. Cell. 131: 952-65. PMID 18045537 DOI: 10.1016/J.Cell.2007.10.016  0.767
2007 Mori T, Vale RD, Tomishige M. How kinesin waits between steps. Nature. 450: 750-4. PMID 18004302 DOI: 10.1038/Nature06346  0.467
2007 Dustin ML, Starr T, Coombs D, Majeau GR, Meier W, Hochman PS, Douglass A, Vale R, Goldstein B, Whitty A. Quantification and modeling of tripartite CD2-, CD58FC chimera (alefacept)-, and CD16-mediated cell adhesion. The Journal of Biological Chemistry. 282: 34748-57. PMID 17911103 DOI: 10.1074/Jbc.M705616200  0.716
2007 Slep KC, Vale RD. Structural basis of microtubule plus end tracking by XMAP215, CLIP-170, and EB1. Molecular Cell. 27: 976-91. PMID 17889670 DOI: 10.1016/J.Molcel.2007.07.023  0.455
2007 Griffis ER, Stuurman N, Vale RD. Spindly, a novel protein essential for silencing the spindle assembly checkpoint, recruits dynein to the kinetochore. The Journal of Cell Biology. 177: 1005-15. PMID 17576797 DOI: 10.1083/Jcb.200702062  0.368
2007 Goshima G, Wollman R, Goodwin SS, Zhang N, Scholey JM, Vale RD, Stuurman N. Genes required for mitotic spindle assembly in Drosophila S2 cells. Science (New York, N.Y.). 316: 417-21. PMID 17412918 DOI: 10.1126/Science.1141314  0.716
2006 Roll-Mecak A, Vale RD. Making more microtubules by severing: a common theme of noncentrosomal microtubule arrays? The Journal of Cell Biology. 175: 849-51. PMID 17178905 DOI: 10.1083/Jcb.200611149  0.365
2006 Tomishige M, Stuurman N, Vale RD. Single-molecule observations of neck linker conformational changes in the kinesin motor protein. Nature Structural & Molecular Biology. 13: 887-94. PMID 17013387 DOI: 10.1038/Nsmb1151  0.49
2006 Pan X, Ou G, Civelekoglu-Scholey G, Blacque OE, Endres NF, Tao L, Mogilner A, Leroux MR, Vale RD, Scholey JM. Mechanism of transport of IFT particles in C. elegans cilia by the concerted action of kinesin-II and OSM-3 motors. The Journal of Cell Biology. 174: 1035-45. PMID 17000880 DOI: 10.1083/Jcb.200606003  0.824
2006 Imanishi M, Endres NF, Gennerich A, Vale RD. Autoinhibition regulates the motility of the C. elegans intraflagellar transport motor OSM-3. The Journal of Cell Biology. 174: 931-7. PMID 17000874 DOI: 10.1083/Jcb.200605179  0.82
2006 Reck-Peterson SL, Yildiz A, Carter AP, Gennerich A, Zhang N, Vale RD. Single-molecule analysis of dynein processivity and stepping behavior. Cell. 126: 335-48. PMID 16873064 DOI: 10.1016/J.Cell.2006.05.046  0.774
2006 Mahoney NM, Goshima G, Douglass AD, Vale RD. Making microtubules and mitotic spindles in cells without functional centrosomes. Current Biology : Cb. 16: 564-9. PMID 16546079 DOI: 10.1016/J.Cub.2006.01.053  0.782
2006 Endres NF, Yoshioka C, Milligan RA, Vale RD. A lever-arm rotation drives motility of the minus-end-directed kinesin Ncd. Nature. 439: 875-8. PMID 16382238 DOI: 10.1038/Nature04320  0.835
2005 Jambhekar A, McDermott K, Sorber K, Shepard KA, Vale RD, Takizawa PA, DeRisi JL. Unbiased selection of localization elements reveals cis-acting determinants of mRNA bud localization in Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 102: 18005-10. PMID 16326802 DOI: 10.1073/Pnas.0509229102  0.317
2005 Goshima G, Wollman R, Stuurman N, Scholey JM, Vale RD. Length control of the metaphase spindle. Current Biology : Cb. 15: 1979-88. PMID 16303556 DOI: 10.1016/J.Cub.2005.09.054  0.67
2005 Goshima G, Nédélec F, Vale RD. Mechanisms for focusing mitotic spindle poles by minus end-directed motor proteins. The Journal of Cell Biology. 171: 229-40. PMID 16247025 DOI: 10.1083/Jcb.200505107  0.421
2005 Dean SO, Rogers SL, Stuurman N, Vale RD, Spudich JA. Distinct pathways control recruitment and maintenance of myosin II at the cleavage furrow during cytokinesis. Proceedings of the National Academy of Sciences of the United States of America. 102: 13473-8. PMID 16174742 DOI: 10.1073/Pnas.0506810102  0.551
2005 Dzhindzhev NS, Rogers SL, Vale RD, Ohkura H. Distinct mechanisms govern the localisation of Drosophila CLIP-190 to unattached kinetochores and microtubule plus-ends. Journal of Cell Science. 118: 3781-90. PMID 16105886 DOI: 10.1242/Jcs.02504  0.498
2005 Douglass AD, Vale RD. Single-molecule microscopy reveals plasma membrane microdomains created by protein-protein networks that exclude or trap signaling molecules in T cells. Cell. 121: 937-50. PMID 15960980 DOI: 10.1016/J.Cell.2005.04.009  0.739
2005 Goshima G, Vale RD. Cell cycle-dependent dynamics and regulation of mitotic kinesins in Drosophila S2 cells. Molecular Biology of the Cell. 16: 3896-907. PMID 15958489 DOI: 10.1091/Mbc.E05-02-0118  0.501
2005 Gibbons IR, Garbarino JE, Tan CE, Reck-Peterson SL, Vale RD, Carter AP. The affinity of the dynein microtubule-binding domain is modulated by the conformation of its coiled-coil stalk. The Journal of Biological Chemistry. 280: 23960-5. PMID 15826937 DOI: 10.1074/Jbc.M501636200  0.768
2005 Roll-Mecak A, Vale RD. The Drosophila homologue of the hereditary spastic paraplegia protein, spastin, severs and disassembles microtubules. Current Biology : Cb. 15: 650-5. PMID 15823537 DOI: 10.1016/J.Cub.2005.02.029  0.34
2005 Mennella V, Rogers GC, Rogers SL, Buster DW, Vale RD, Sharp DJ. Functionally distinct kinesin-13 family members cooperate to regulate microtubule dynamics during interphase. Nature Cell Biology. 7: 235-45. PMID 15723056 DOI: 10.1038/Ncb1222  0.43
2005 Slep KC, Rogers SL, Elliott SL, Ohkura H, Kolodziej PA, Vale RD. Structural determinants for EB1-mediated recruitment of APC and spectraplakins to the microtubule plus end. The Journal of Cell Biology. 168: 587-98. PMID 15699215 DOI: 10.1083/Jcb.200410114  0.439
2004 Reck-Peterson SL, Vale RD. Molecular dissection of the roles of nucleotide binding and hydrolysis in dynein's AAA domains in Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 101: 14305. PMID 15693149 DOI: 10.1073/Pnas.0404506101  0.661
2004 Rogers SL, Wiedemann U, Häcker U, Turck C, Vale RD. Drosophila RhoGEF2 associates with microtubule plus ends in an EB1-dependent manner. Current Biology : Cb. 14: 1827-33. PMID 15498490 DOI: 10.1016/J.Cub.2004.09.078  0.468
2004 Lawrence CJ, Dawe RK, Christie KR, Cleveland DW, Dawson SC, Endow SA, Goldstein LS, Goodson HV, Hirokawa N, Howard J, Malmberg RL, McIntosh JR, Miki H, Mitchison TJ, Okada Y, ... ... Vale RD, et al. A standardized kinesin nomenclature. The Journal of Cell Biology. 167: 19-22. PMID 15479732 DOI: 10.1083/Jcb.200408113  0.621
2004 Collins SR, Douglass A, Vale RD, Weissman JS. Mechanism of prion propagation: amyloid growth occurs by monomer addition. Plos Biology. 2: e321. PMID 15383837 DOI: 10.1371/Journal.Pbio.0020321  0.714
2004 Klopfenstein DR, Vale RD. The lipid binding pleckstrin homology domain in UNC-104 kinesin is necessary for synaptic vesicle transport in Caenorhabditis elegans. Molecular Biology of the Cell. 15: 3729-39. PMID 15155810 DOI: 10.1091/Mbc.E04-04-0326  0.393
2004 Reck-Peterson SL, Vale RD. Molecular dissection of the roles of nucleotide binding and hydrolysis in dynein's AAA domains in Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 101: 1491-5. PMID 14755060 DOI: 10.1073/Pnas.2637011100  0.717
2004 Yildiz A, Tomishige M, Vale RD, Selvin PR. Kinesin walks hand-over-hand. Science (New York, N.Y.). 303: 676-8. PMID 14684828 DOI: 10.1126/Science.1093753  0.398
2004 Rogers GC, Rogers SL, Schwimmer TA, Ems-McClung SC, Walczak CE, Vale RD, Scholey JM, Sharp DJ. Two mitotic kinesins cooperate to drive sister chromatid separation during anaphase. Nature. 427: 364-70. PMID 14681690 DOI: 10.1038/Nature02256  0.66
2004 Tomishige M, Stuurman N, Vale RD. 3P176 Observation of conformational changes of kinesin walking along microtubules using single molecule FRET technique Seibutsu Butsuri. 44: S233. DOI: 10.2142/Biophys.44.S233_4  0.327
2003 Al-Bassam J, Cui Y, Klopfenstein D, Carragher BO, Vale RD, Milligan RA. Distinct conformations of the kinesin Unc104 neck regulate a monomer to dimer motor transition. The Journal of Cell Biology. 163: 743-53. PMID 14638858 DOI: 10.1083/Jcb.200308020  0.433
2003 Vale RD. Myosin V motor proteins: marching stepwise towards a mechanism. The Journal of Cell Biology. 163: 445-50. PMID 14610051 DOI: 10.1083/Jcb.200308093  0.459
2003 Shepard KA, Gerber AP, Jambhekar A, Takizawa PA, Brown PO, Herschlag D, DeRisi JL, Vale RD. Widespread cytoplasmic mRNA transport in yeast: identification of 22 bud-localized transcripts using DNA microarray analysis. Proceedings of the National Academy of Sciences of the United States of America. 100: 11429-34. PMID 13679573 DOI: 10.1073/Pnas.2033246100  0.316
2003 Rogers SL, Wiedemann U, Stuurman N, Vale RD. Molecular requirements for actin-based lamella formation in Drosophila S2 cells. The Journal of Cell Biology. 162: 1079-88. PMID 12975351 DOI: 10.1083/Jcb.200303023  0.407
2003 Goshima G, Vale RD. The roles of microtubule-based motor proteins in mitosis: comprehensive RNAi analysis in the Drosophila S2 cell line. The Journal of Cell Biology. 162: 1003-16. PMID 12975346 DOI: 10.1083/Jcb.200303022  0.509
2003 Yaffe MP, Stuurman N, Vale RD. Mitochondrial positioning in fission yeast is driven by association with dynamic microtubules and mitotic spindle poles. Proceedings of the National Academy of Sciences of the United States of America. 100: 11424-8. PMID 12972644 DOI: 10.1073/Pnas.1534703100  0.433
2003 Rothenberg ME, Rogers SL, Vale RD, Jan LY, Jan YN. Drosophila pod-1 crosslinks both actin and microtubules and controls the targeting of axons. Neuron. 39: 779-91. PMID 12948445 DOI: 10.1016/S0896-6273(03)00508-7  0.357
2003 Naber N, Minehardt TJ, Rice S, Chen X, Grammer J, Matuska M, Vale RD, Kollman PA, Car R, Yount RG, Cooke R, Pate E. Closing of the nucleotide pocket of kinesin-family motors upon binding to microtubules. Science (New York, N.Y.). 300: 798-801. PMID 12730601 DOI: 10.1126/Science.1082374  0.78
2003 Naber N, Rice S, Matuska M, Vale RD, Cooke R, Pate E. EPR spectroscopy shows a microtubule-dependent conformational change in the kinesin switch 1 domain. Biophysical Journal. 84: 3190-6. PMID 12719248 DOI: 10.1016/S0006-3495(03)70043-5  0.727
2003 Rice S, Cui Y, Sindelar C, Naber N, Matuska M, Vale R, Cooke R. Thermodynamic properties of the kinesin neck-region docking to the catalytic core Biophysical Journal. 84: 1844-1854. PMID 12609886 DOI: 10.1016/S0006-3495(03)74992-3  0.735
2003 Vale RD. The molecular motor toolbox for intracellular transport. Cell. 112: 467-80. PMID 12600311 DOI: 10.1016/S0092-8674(03)00111-9  0.453
2003 Tomishige M, Vale RD. Effect of changing the length of the neck linker on the processive movement of kinesin Seibutsu Butsuri. 43: S98. DOI: 10.2142/Biophys.43.S98_3  0.341
2002 Klopfenstein DR, Holleran EA, Vale RD. Kinesin motors and microtubule-based organelle transport in Dictyostelium discoideum. Journal of Muscle Research and Cell Motility. 23: 631-8. PMID 12952062 DOI: 10.1023/A:1024403006680  0.48
2002 Tomishige M, Klopfenstein DR, Vale RD. Conversion of Unc104/KIF1A kinesin into a processive motor after dimerization. Science (New York, N.Y.). 297: 2263-7. PMID 12351789 DOI: 10.1126/Science.1073386  0.479
2002 Rogers SL, Rogers GC, Sharp DJ, Vale RD. Drosophila EB1 is important for proper assembly, dynamics, and positioning of the mitotic spindle. The Journal of Cell Biology. 158: 873-84. PMID 12213835 DOI: 10.1083/Jcb.200202032  0.437
2002 Klopfenstein DR, Tomishige M, Stuurman N, Vale RD. Role of phosphatidylinositol(4,5)bisphosphate organization in membrane transport by the Unc104 kinesin motor. Cell. 109: 347-58. PMID 12015984 DOI: 10.1016/S0092-8674(02)00708-0  0.384
2002 Irie K, Tadauchi T, Takizawa PA, Vale RD, Matsumoto K, Herskowitz I. The Khd1 protein, which has three KH RNA-binding motifs, is required for proper localization of ASH1 mRNA in yeast. The Embo Journal. 21: 1158-67. PMID 11867544 DOI: 10.1093/Emboj/21.5.1158  0.358
2002 Tomishige M, Vale RD. 1O1400 Dimerization triggers fast, processive movement of Unc104/KIF1A "monomeric" kinesin along microtubules Seibutsu Butsuri. 42: S90. DOI: 10.2142/Biophys.42.S90_2  0.361
2000 Dell KR, Turck CW, Vale RD. Mitotic phosphorylation of the dynein light intermediate chain is mediated by cdc2 kinase. Traffic (Copenhagen, Denmark). 1: 38-44. PMID 11208058 DOI: 10.1034/J.1600-0854.2000.010107.X  0.325
2000 Klopfenstein DR, Vale RD, Rogers SL. Motor protein receptors: moonlighting on other jobs. Cell. 103: 537-40. PMID 11106727 DOI: 10.1016/S0092-8674(00)00144-6  0.45
2000 Wilhelm JE, Vale RD, Hegde RS. Coordinate control of translation and localization of Vg1 mRNA in Xenopus oocytes. Proceedings of the National Academy of Sciences of the United States of America. 97: 13132-7. PMID 11087864 DOI: 10.1073/Pnas.97.24.13132  0.703
2000 Thorn KS, Ubersax JA, Vale RD. Engineering the processive run length of the kinesin motor. The Journal of Cell Biology. 151: 1093-100. PMID 11086010 DOI: 10.1083/Jcb.151.5.1093  0.759
2000 Tomishige M, Vale RD. Controlling kinesin by reversible disulfide cross-linking. Identifying the motility-producing conformational change. The Journal of Cell Biology. 151: 1081-92. PMID 11086009 DOI: 10.1083/Jcb.151.5.1081  0.478
2000 Takizawa PA, DeRisi JL, Wilhelm JE, Vale RD. Plasma membrane compartmentalization in yeast by messenger RNA transport and a septin diffusion barrier. Science (New York, N.Y.). 290: 341-4. PMID 11030653 DOI: 10.1126/Science.290.5490.341  0.712
2000 Khan S, Pierce D, Vale RD. Interactions of the chemotaxis signal protein CheY with bacterial flagellar motors visualized by evanescent wave microscopy. Current Biology : Cb. 10: 927-30. PMID 10959841 DOI: 10.1016/S0960-9822(00)00629-1  0.42
2000 Vale RD. AAA proteins. Lords of the ring. The Journal of Cell Biology. 150: F13-9. PMID 10893253 DOI: 10.1083/Jcb.150.1.F13  0.323
2000 Vale RD, Case R, Sablin E, Hart C, Fletterick R. Searching for kinesin's mechanical amplifier. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 355: 449-57. PMID 10836498 DOI: 10.1098/Rstb.2000.0586  0.834
2000 Shimizu T, Thorn KS, Ruby A, Vale RD. ATPase kinetic characterization and single molecule behavior of mutant human kinesin motors defective in microtubule-based motility. Biochemistry. 39: 5265-73. PMID 10819995 DOI: 10.1021/Bi9928344  0.76
2000 Takizawa PA, Vale RD. The myosin motor, Myo4p, binds Ash1 mRNA via the adapter protein, She3p. Proceedings of the National Academy of Sciences of the United States of America. 97: 5273-8. PMID 10792032 DOI: 10.1073/Pnas.080585897  0.413
2000 Vale RD, Milligan RA. The way things move: looking under the hood of molecular motor proteins. Science (New York, N.Y.). 288: 88-95. PMID 10753125 DOI: 10.1126/Science.288.5463.88  0.485
2000 Thorn KS, Naber N, Matuska M, Vale RD, Cooke R. A novel method of affinity-purifying proteins using a bis-arsenical fluorescein. Protein Science : a Publication of the Protein Society. 9: 213-7. PMID 10716173 DOI: 10.1110/Ps.9.2.213  0.693
2000 Hopkins SC, Vale RD, Kuntz ID. Inhibitors of kinesin activity from structure-based computer screening. Biochemistry. 39: 2805-14. PMID 10704233 DOI: 10.1021/Bi992474K  0.381
2000 Case RB, Rice S, Hart CL, Ly B, Vale RD. Role of the kinesin neck linker and catalytic core in microtubule-based motility. Current Biology : Cb. 10: 157-60. PMID 10679326 DOI: 10.1016/S0960-9822(00)00316-X  0.831
2000 Wilhelm JE, Mansfield J, Hom-Booher N, Wang S, Turck CW, Hazelrigg T, Vale RD. Isolation of a ribonucleoprotein complex involved in mRNA localization in Drosophila oocytes. The Journal of Cell Biology. 148: 427-40. PMID 10662770 DOI: 10.1083/Jcb.148.3.427  0.713
2000 Govindan B, Vale RD. Characterization of a microtubule assembly inhibitor from Xenopus oocytes. Cell Motility and the Cytoskeleton. 45: 51-7. PMID 10618166 DOI: 10.1002/(Sici)1097-0169(200001)45:1<51::Aid-Cm5>3.0.Co;2-7  0.377
2000 Tomishige M, Vale RD. Crosslinking of the kinesin neck region : effect on processive movement along microtubules Seibutsu Butsuri. 40: S69. DOI: 10.2142/Biophys.40.S69_4  0.381
1999 Rice S, Lin AW, Safer D, Hart CL, Naber N, Carragher BO, Cain SM, Pechatnikova E, Wilson-Kubalek EM, Whittaker M, Pate E, Cooke R, Taylor EW, Milligan RA, Vale RD. A structural change in the kinesin motor protein that drives motility. Nature. 402: 778-84. PMID 10617199 DOI: 10.1038/45483  0.771
1999 Vale RD. Millennial musings on molecular motors. Trends in Cell Biology. 9: M38-42. PMID 10611679 DOI: 10.1016/S0168-9525(99)01886-7  0.395
1999 Friedman DS, Vale RD. Single-molecule analysis of kinesin motility reveals regulation by the cargo-binding tail domain. Nature Cell Biology. 1: 293-7. PMID 10559942 DOI: 10.1038/13008  0.505
1999 Pollock N, de Hostos EL, Turck CW, Vale RD. Reconstitution of membrane transport powered by a novel dimeric kinesin motor of the Unc104/KIF1A family purified from Dictyostelium. The Journal of Cell Biology. 147: 493-506. PMID 10545495 DOI: 10.1083/Jcb.147.3.493  0.461
1999 Hartman JJ, Vale RD. Microtubule disassembly by ATP-dependent oligomerization of the AAA enzyme katanin. Science (New York, N.Y.). 286: 782-5. PMID 10531065 DOI: 10.1126/Science.286.5440.782  0.398
1999 Pierce DW, Hom-Booher N, Otsuka AJ, Vale RD. Single-molecule behavior of monomeric and heteromeric kinesins. Biochemistry. 38: 5412-21. PMID 10220328 DOI: 10.1021/Bi9830009  0.508
1999 Pierce DW, Vale RD. Single-molecule fluorescence detection of green fluorescence protein and application to single-protein dynamics Methods in Cell Biology. 49-73. PMID 9891374 DOI: 10.1016/S0091-679X(08)61948-2  0.327
1999 Sharp DJ, McDonald KL, Brown HM, Matthies HJ, Walczak C, Vale RD, Mitchison TJ, Scholey JM. The bipolar kinesin, KLP61F, cross-links microtubules within interpolar microtubule bundles of Drosophila embryonic mitotic spindles. The Journal of Cell Biology. 144: 125-38. PMID 9885249 DOI: 10.1083/Jcb.144.1.125  0.678
1998 Kull FJ, Vale RD, Fletterick RJ. The case for a common ancestor: kinesin and myosin motor proteins and G proteins. Journal of Muscle Research and Cell Motility. 19: 877-86. PMID 10047987 DOI: 10.1023/A:1005489907021  0.711
1998 Sablin EP, Case RB, Dai SC, Hart CL, Ruby A, Vale RD, Fletterick RJ. Direction determination in the minus-end-directed kinesin motor ncd. Nature. 395: 813-6. PMID 9796817 DOI: 10.1038/27463  0.837
1998 Prahlad V, Yoon M, Moir RD, Vale RD, Goldman RD. Rapid movements of vimentin on microtubule tracks: Kinesin-dependent assembly of intermediate filament networks Journal of Cell Biology. 143: 159-170. PMID 9763428 DOI: 10.1083/Jcb.143.1.159  0.439
1998 Pierce DW, Vale RD. [14] Assaying processive movement of kinesin by fluorescence microscopy Methods in Enzymology. 298: 154-171. PMID 9751879 DOI: 10.1016/S0076-6879(98)98016-8  0.323
1998 Wells SE, Hillner PE, Vale RD, Sachs AB. Circularization of mRNA by eukaryotic translation initiation factors. Molecular Cell. 2: 135-40. PMID 9702200 DOI: 10.1016/S1097-2765(00)80122-7  0.311
1998 De Hostos EL, McCaffrey G, Sucgang R, Pierce DW, Vale RD. A developmentally regulated kinesin-related motor protein from Dictyostelium discoideum Molecular Biology of the Cell. 9: 2093-2106. PMID 9693369 DOI: 10.1091/Mbc.9.8.2093  0.43
1998 Pollock N, Koonce MP, de Hostos EL, Vale RD. In vitro microtubule-based organelle transport in wild-type Dictyostelium and cells overexpressing a truncated dynein heavy chain. Cell Motility and the Cytoskeleton. 40: 304-14. PMID 9678672 DOI: 10.1002/(Sici)1097-0169(1998)40:3<304::Aid-Cm8>3.0.Co;2-C  0.452
1998 Hartman JJ, Mahr J, McNally K, Okawa K, Iwamatsu A, Thomas S, Cheesman S, Heuser J, Vale RD, McNally FJ. Katanin, a microtubule-severing protein, is a novel AAA ATPase that targets to the centrosome using a WD40-containing subunit. Cell. 93: 277-87. PMID 9568719 DOI: 10.1016/S0092-8674(00)81578-0  0.369
1998 Lohman TM, Thorn K, Vale RD. Staying on track: common features of DNA helicases and microtubule motors. Cell. 93: 9-12. PMID 9546385 DOI: 10.1016/S0092-8674(00)81139-3  0.725
1998 Romberg L, Pierce DW, Vale RD. Role of the kinesin neck region in processive microtubule-based motility Journal of Cell Biology. 140: 1407-1416. PMID 9508773 DOI: 10.1083/Jcb.140.6.1407  0.5
1997 Funatsu T, Harada Y, Higuchi H, Tokunaga M, Saito K, Ishii Y, Vale RD, Yanagida T. Imaging and nano-manipulation of single biomolecules Biophysical Chemistry. 68: 63-72. PMID 9468610 DOI: 10.1016/S0301-4622(97)00008-2  0.347
1997 Vale RD, Fletterick RJ. The design plan of kinesin motors. Annual Review of Cell and Developmental Biology. 13: 745-77. PMID 9442886 DOI: 10.1146/Annurev.Cellbio.13.1.745  0.647
1997 Case RB, Pierce DW, Hom-Booher N, Hart CL, Vale RD. The directional preference of kinesin motors is specified by an element outside of the motor catalytic domain Cell. 90: 959-966. PMID 9298907 DOI: 10.1016/S0092-8674(00)80360-8  0.805
1997 Takizawa PA, Sil A, Swedlow JR, Herskowitz I, Vale RD. Actin-dependent localization of an RNA encoding a cell-fate determinant in yeast. Nature. 389: 90-3. PMID 9288973 DOI: 10.1038/38015  0.371
1997 Sosa H, Dias DP, Hoenger A, Whittaker M, Wilson-Kubalek E, Sablin E, Fletterick RJ, Vale RD, Milligan RA. A model for the microtubule-Ncd motor protein complex obtained by cryo-electron microscopy and image analysis. Cell. 90: 217-24. PMID 9244296 DOI: 10.1016/S0092-8674(00)80330-X  0.663
1997 Woehlke G, Ruby AK, Hart CL, Ly B, Hom-Booher N, Vale RD. Microtubule interaction site of the kinesin motor Cell. 90: 207-216. PMID 9244295 DOI: 10.1016/S0092-8674(00)80329-3  0.47
1997 Coppin CM, Pierce DW, Hsu L, Vale RD. The load dependence of kinesin's mechanical cycle Proceedings of the National Academy of Sciences of the United States of America. 94: 8539-8544. PMID 9238012 DOI: 10.1073/Pnas.94.16.8539  0.35
1997 Pierce DW, Hom-Booher N, Vale RD. Imaging individual green fluorescent proteins [7] Nature. 388: 338. PMID 9237750 DOI: 10.1038/41009  0.353
1997 Tripet B, Vale RD, Hodges RS. Demonstration of coiled-coil interactions within the kinesin neck region using synthetic peptides: Implications for motor activity Journal of Biological Chemistry. 272: 8946-8956. PMID 9083016 DOI: 10.1074/Jbc.272.14.8946  0.404
1997 Vale RD, Pierce D, Woehlke G, Coppin C, Romberg L. Mechanism of motility by the microtubule-based motor kinesin Faseb Journal. 11: A999.  0.378
1996 Wilhelm JE, Vale RD. A one-hybrid system for detecting RNA-protein interactions. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 1: 317-23. PMID 9133665 DOI: 10.1046/J.1365-2443.1996.25026.X  0.696
1996 Vignali G, Niclas J, Sprocati MT, Vale RD, Sirtori C, Navone F. Differential Expression of Ubiquitous and Neuronal Kinesin Heavy Chains During Differentiation of Human Neuroblastoma and PC12 Cells European Journal of Neuroscience. 8: 536-544. PMID 8963445 DOI: 10.1111/J.1460-9568.1996.Tb01238.X  0.332
1996 McNally FJ, Okawa K, Iwamatsu A, Vale RD. Katanin, the microtubule-severing ATPase, is concentrated at centrosomes Journal of Cell Science. 109: 561-567. PMID 8907702  0.334
1996 Vale RD. Switches, latches, and amplifiers: common themes of G proteins and molecular motors The Journal of Cell Biology. 135: 291-302. PMID 8896589 DOI: 10.1083/Jcb.135.2.291  0.432
1996 Coppin CM, Finer JT, Spudich JA, Vale RD. Detection of sub-8-nm movements of kinesin by high-resolution optical-trap microscopy. Proceedings of the National Academy of Sciences of the United States of America. 93: 1913-7. PMID 8700858 DOI: 10.1073/Pnas.93.5.1913  0.625
1996 Niclas J, Allan VJ, Vale RD. Cell cycle regulation of dynein association with membranes modulates microtubule-based organelle transport Journal of Cell Biology. 133: 585-593. PMID 8636233 DOI: 10.1083/Jcb.133.3.585  0.447
1996 Sablin EP, Kull FJ, Cooke R, Vale RD, Fletterick RJ. Crystal structure of the motor domain of the kinesin-related motor ncd. Nature. 380: 555-9. PMID 8606780 DOI: 10.1038/380555A0  0.767
1996 Kull FJ, Sablin EP, Lau R, Fletterick RJ, Vale RD. Crystal structure of the kinesin motor domain reveals a structural similarity to myosin. Nature. 380: 550-5. PMID 8606779 DOI: 10.1107/S0108767396090939  0.747
1996 Vale RD, Funatsu T, Pierce DW, Romberg L, Harada Y, Yanagida T. Direct observation of single kinesin molecules moving along microtubules Nature. 380: 451-453. PMID 8602245 DOI: 10.1038/380451A0  0.51
1996 Sablin EP, Kull FJ, Cooke R, Vale RD, Fletterick RJ. Three-dimensional structure of the motor domain of NCD, a kinesin-related motor with reversed polarity of movement Acta Crystallographica Section a Foundations of Crystallography. 52: C211-C211. DOI: 10.1107/S0108767396090927  0.742
1995 Shimizu T, Toyoshima YY, Edamatsu M, Vale RD. Comparison of the motile and enzymatic properties of two microtubule minus-end-directed motors, ncd and cytoplasmic dynein Biochemistry. 34: 1575-1582. PMID 7849016 DOI: 10.1021/Bi00005A013  0.518
1995 Coppin CM, Finer JT, Spudich JA, Vale RD. Measurement of the isometric force exerted by a single kinesin molecule. Biophysical Journal. 68: 242S-244S. PMID 7787084  0.443
1995 Hoenger A, Sablin EP, Vale RD, Fletterick RJ, Milligan RA. Three-dimensional structure of a tubulin-motor-protein complex. Nature. 376: 271-4. PMID 7617040 DOI: 10.1038/376271A0  0.671
1995 Shimizu T, Sablin E, Vale RD, Fletterick R, Pechatnikova E, Taylor EW. Expression, purification, ATPase properties, and microtubule-binding properties of the ncd motor domain Biochemistry. 34: 13259-13266. PMID 7548090 DOI: 10.1021/Bi00040A042  0.649
1994 Malik F, Brillinger D, Vale RD. High-resolution tracking of microtubule motility driven by a single kinesin motor Proceedings of the National Academy of Sciences of the United States of America. 91: 4584-4588. PMID 8183952 DOI: 10.1073/Pnas.91.10.4584  0.493
1994 Vale RD. Getting a grip on myosin Cell. 78: 733-738. PMID 8087841 DOI: 10.1016/S0092-8674(94)90402-2  0.335
1994 Vale RD, Coppin CM, Malik F, Kull FJ, Milligan RA. Tubulin GTP hydrolysis influences the structure, mechanical properties, and kinesin-driven transport of microtubules. The Journal of Biological Chemistry. 269: 23769-75. PMID 7916345  0.65
1994 Niclas J, Navone F, Hom-Booker N, Vale RD. Cloning and localization of a conventional kinesin motor expressed exclusively in neurons Neuron. 12: 1059-1072. PMID 7514426 DOI: 10.1016/0896-6273(94)90314-X  0.412
1993 Vale RD. Measuring single protein motors at work Science. 260: 169-170. PMID 8469971 DOI: 10.1126/Science.8469971  0.411
1993 Romberg L, Vale RD. Chemomechanical cycle of kinesin differs from that of myosin Nature. 361: 168-170. PMID 8421522 DOI: 10.1038/361168A0  0.474
1993 Wilhelm JE, Vale RD. RNA on the move: the mRNA localization pathway. The Journal of Cell Biology. 123: 269-74. PMID 8408211 DOI: 10.1083/Jcb.123.2.269  0.668
1993 Shimizu T, Toyoshima YY, Vale RD. Use of ATP analogs in motor assays Methods in Cell Biology. 39: 167-177. PMID 8246796 DOI: 10.1016/S0091-679X(08)60169-7  0.435
1993 McNally FJ, Vale RD. Identification of katanin, an ATPase that severs and disassembles stable microtubules Cell. 75: 419-429. PMID 8221885 DOI: 10.1016/0092-8674(93)90377-3  0.44
1992 Navone F, Niclas J, Hom-Booher N, Sparks L, Bernstein HD, McCaffrey G, Vale RD. Cloning and expression of a human kinesin heavy chain gene: Interaction of the COOH-terminal domain with cytoplasmic microtubules in transfected CV-1 cells Journal of Cell Biology. 117: 1263-1275. PMID 1607388 DOI: 10.1083/Jcb.117.6.1263  0.446
1992 Ferreira A, Niclas J, Vale RD, Banker G, Kosik KS. Suppression of kinesin expression in cultured hippocampal neurons using antisense oligonucleotides. The Journal of Cell Biology. 117: 595-606. PMID 1533397 DOI: 10.1083/Jcb.117.3.595  0.339
1992 Vale RD, Malik F, Brown D. Directional instability of microtubule transport in the presence of kinesin and dynein, two opposite polarity motor proteins Journal of Cell Biology. 119: 1589-1596. PMID 1469050 DOI: 10.1083/Jcb.119.6.1589  0.523
1992 Vale RD. Microtubule motors: many new models off the assembly line Trends in Biochemical Sciences. 17: 300-304. PMID 1412704 DOI: 10.1016/0968-0004(92)90440-K  0.467
1992 Goldstein LS, Vale RD. Cell biology. New cytoskeletal liaisons. Nature. 359: 193-4. PMID 1388245 DOI: 10.1038/359193A0  0.455
1991 Allan VJ, Vale RD. Cell cycle control of microtubule-based membrane transport and tubule formation in vitro Journal of Cell Biology. 113: 347-359. PMID 2010466 DOI: 10.1083/Jcb.113.2.347  0.391
1991 Goldstein LS, Vale RD. Motor proteins. A brave new world for dynein. Nature. 352: 569-70. PMID 1830924 DOI: 10.1038/352569A0  0.563
1991 Schliwa M, Shimizu T, Vale RD, Euteneuer U. Nucleotide specificities of anterograde and retrograde organelle transport in Reticulomyxa are indistinguishable. The Journal of Cell Biology. 112: 1199-203. PMID 1825662 DOI: 10.1083/Jcb.112.6.1199  0.435
1991 Shimizu T, Furusawa K, Ohashi S, Toyoshima YY, Okuno M, Malik F, Vale RD. Nucleotide specificity of the enzymatic and motile activities of dynein, kinesin, and heavy meromyosin. The Journal of Cell Biology. 112: 1189-97. PMID 1825661 DOI: 10.1083/Jcb.112.6.1189  0.425
1991 Vale RD. Severing of stable microtubules by a mitotically activated protein in Xenopus egg extracts Cell. 64: 827-839. PMID 1671762 DOI: 10.1016/0092-8674(91)90511-V  0.406
1990 Vale RD, Oosawa F. Protein motors and Maxwell's demons: Does mechanochemical transduction involve a thermal ratchet? Advances in Biophysics. 26: 97-134. PMID 2150583 DOI: 10.1016/0065-227X(90)90009-I  0.438
1990 Vale RD. Microtubule-based motor proteins Current Opinion in Cell Biology. 2: 15-22. PMID 2139334 DOI: 10.1016/S0955-0674(05)80025-0  0.462
1990 Vale RD, Goldstein LS. One motor, many tails: an expanding repertoire of force-generating enzymes. Cell. 60: 883-5. PMID 2138513 DOI: 10.1016/0092-8674(90)90334-B  0.366
1989 Vale RD, Soll DR, Gibbons IR. One-dimensional diffusion of microtubules bound to flagellar dynein Cell. 59: 915-925. PMID 2531633 DOI: 10.1016/0092-8674(89)90614-4  0.357
1989 Howard J, Hudspeth AJ, Vale RD. Movement of microtubules by single kinesin molecules. Nature. 342: 154-8. PMID 2530455 DOI: 10.1038/342154A0  0.47
1989 Vale RD, Toyoshima YY. Microtubule translocation properties of intact and proteolytically digested dyneins from Tetrahymena cilia Journal of Cell Biology. 108: 2327-2334. PMID 2525562 DOI: 10.1083/Jcb.108.6.2327  0.444
1989 McCaffrey G, Vale R. Identification of a kinesin-like microtubule-based motor protein in Dictyostelium discoideum. The Embo Journal. 8: 3229-3234. DOI: 10.1002/J.1460-2075.1989.Tb08482.X  0.525
1988 Vale RD, Hotani H. Formation of membrane networks in vitro by kinesin-driven microtubule movement Journal of Cell Biology. 107: 2233-2241. PMID 3143735 DOI: 10.1083/Jcb.107.6.2233  0.361
1988 Vale RD, Yano Toyoshima Y. Rotation and translocation of microtubules in vitro induced by dyneins from Tetrahymena cilia Cell. 52: 459-469. PMID 2964278 DOI: 10.1016/S0092-8674(88)80038-2  0.427
1987 Vale RD. Intracellular transport using microtubule-based motors Annual Review of Cell Biology. 3: 347-378. PMID 3120763 DOI: 10.1146/Annurev.Cb.03.110187.002023  0.481
1987 Sheetz MP, Vale R, Schnapp B, Schroer T, Reese T. Movements of vesicles on microtubules Annals of the New York Academy of Sciences. 493: 409-416. PMID 3109300 DOI: 10.1111/J.1749-6632.1987.Tb27227.X  0.785
1987 Porter ME, Scholey JM, Stemple DL, Vigers GP, Vale RD, Sheetz MP, McIntosh JR. Characterization of the microtubule movement produced by sea urchin egg kinesin. The Journal of Biological Chemistry. 262: 2794-802. PMID 3102475  0.741
1986 Sheetz MP, Vale R, Schnapp B, Schroer T, Reese T. Vesicle movements and microtubule-based motors Journal of Cell Science. Supplement. 5: 181-188. PMID 2443518 DOI: 10.1242/Jcs.1986.Supplement_5.11  0.791
1986 Schnapp BJ, Vale RD, Sheetz MP, Reese TS. Microtubules and the mechanism of directed organelle movement. Annals of the New York Academy of Sciences. 466: 909-18. PMID 2425684 DOI: 10.1111/J.1749-6632.1986.Tb38476.X  0.663
1986 Vale RD, Scholey JM, Sheetz MP. Kinesin: possible biological roles for a new microtubule motor Trends in Biochemical Sciences. 11: 464-468. DOI: 10.1016/0968-0004(86)90248-3  0.792
1985 Vale RD, Reese TS, Sheetz MP. Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility. Cell. 42: 39-50. PMID 3926325 DOI: 10.1016/S0092-8674(85)80099-4  0.679
1985 Vale RD, Schnapp BJ, Reese TS, Sheetz MP. Organelle, bead, and microtubule translocations promoted by soluble factors from the squid giant axon. Cell. 40: 559-69. PMID 2578887 DOI: 10.1016/0092-8674(85)90204-1  0.672
1985 Schnapp BJ, Vale RD, Sheetz MP, Reese TS. Single microtubules from squid axoplasm support bidirectional movement of organelles. Cell. 40: 455-62. PMID 2578325 DOI: 10.1016/0092-8674(85)90160-6  0.666
1985 Vale RD, Schnapp BJ, Reese TS, Sheetz MP. Movement of organelles along filaments dissociated from the axoplasm of the squid giant axon. Cell. 40: 449-54. PMID 2578324 DOI: 10.1016/0092-8674(85)90159-X  0.676
1985 Vale RD, Schnapp BJ, Mitchison T, Steuer E, Reese TS, Sheetz MP. Different axoplasmic proteins generate movement in opposite directions along microtubules in vitro. Cell. 43: 623-32. PMID 2416467 DOI: 10.1016/0092-8674(85)90234-X  0.692
1984 Vale RD, Szent-Gyorgyi AG, Sheetz MP. Movement of scallop myosin on Nitella actin filaments: regulation by calcium. Proceedings of the National Academy of Sciences of the United States of America. 81: 6775-8. PMID 6238334 DOI: 10.1073/Pnas.81.21.6775  0.628
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