Erika L. F. Holzbaur - Publications

1992- University of Pennsylvania, Philadelphia, PA, United States 
cell biology, neurodegeneration, microtubules, dynein, kinesin

158 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Simpson CL, Tokito MK, Uppala R, Sarkar MK, Gudjonsson JE, Holzbaur ELF. NIX initiates mitochondrial fragmentation via DRP1 to drive epidermal differentiation. Cell Reports. 34: 108689. PMID 33535046 DOI: 10.1016/j.celrep.2021.108689  0.88
2020 Lee IG, Cason SE, Alqassim SS, Holzbaur ELF, Dominguez R. A tunable LIC1-adaptor interaction modulates dynein activity in a cargo-specific manner. Nature Communications. 11: 5695. PMID 33173051 DOI: 10.1038/s41467-020-19538-7  0.36
2020 Sase S, Almad AA, Boecker CA, Guedes-Dias P, Li JJ, Takanohashi A, Patel A, McCaffrey T, Patel H, Sirdeshpande D, Curiel J, Shih-Hwa Liu J, Padiath Q, Holzbaur EL, Scherer SS, et al. mutations result in both glial and neuronal degeneration in an H-ABC leukodystrophy mouse model. Elife. 9. PMID 32463361 DOI: 10.7554/eLife.52986  0.56
2019 Twelvetrees AE, Lesept F, Holzbaur ELF, Kittler JT. The adaptor proteins HAP1a and GRIP1 collaborate to activate kinesin-1 isoform KIF5C. Journal of Cell Science. PMID 31757889 DOI: 10.1242/jcs.215822  0.72
2019 Guedes-Dias P, Holzbaur ELF. Axonal transport: Driving synaptic function. Science (New York, N.Y.). 366. PMID 31601744 DOI: 10.1126/science.aaw9997  0.56
2019 Stavoe AK, Gopal PP, Gubas A, Tooze SA, Holzbaur EL. Expression of WIPI2B counteracts age-related decline in autophagosome biogenesis in neurons. Elife. 8. PMID 31309927 DOI: 10.7554/eLife.44219  0.8
2019 Guedes-Dias P, Nirschl JJ, Abreu N, Tokito MK, Janke C, Magiera MM, Holzbaur ELF. Kinesin-3 Responds to Local Microtubule Dynamics to Target Synaptic Cargo Delivery to the Presynapse. Current Biology : Cb. 29: 268-282.e8. PMID 30612907 DOI: 10.1016/j.cub.2018.11.065  1
2019 Moore AS, Holzbaur ELF. Imaging the Dynamics of Mitophagy in Live Cells. Methods in Molecular Biology (Clifton, N.J.). 1880: 601-610. PMID 30610725 DOI: 10.1007/978-1-4939-8873-0_39  0.76
2018 Moore AS, Holzbaur ELF. Mitochondrial-cytoskeletal interactions: dynamic associations that facilitate network function and remodeling. Current Opinion in Physiology. 3: 94-100. PMID 30555978 DOI: 10.1016/j.cophys.2018.03.003  0.76
2018 Olenick MA, Dominguez R, Holzbaur ELF. Dynein activator Hook1 is required for trafficking of BDNF-signaling endosomes in neurons. The Journal of Cell Biology. PMID 30373907 DOI: 10.1083/jcb.201805016  0.36
2018 Klinman E, Holzbaur ELF. Walking Forward with Kinesin. Trends in Neurosciences. 41: 555-556. PMID 30143179 DOI: 10.1016/j.tins.2018.07.006  0.8
2018 Lee IG, Olenick MA, Boczkowska M, Franzini-Armstrong C, Holzbaur ELF, Dominguez R. A conserved interaction of the dynein light intermediate chain with dynein-dynactin effectors necessary for processivity. Nature Communications. 9: 986. PMID 29515126 DOI: 10.1038/s41467-018-03412-8  0.36
2018 McIntosh BB, Pyrpassopoulos S, Holzbaur ELF, Ostap EM. Opposing Kinesin and Myosin-I Motors Drive Membrane Deformation and Tubulation along Engineered Cytoskeletal Networks. Current Biology : Cb. PMID 29337076 DOI: 10.1016/j.cub.2017.12.007  0.72
2017 Klinman E, Tokito M, Holzbaur ELF. CDK5-dependent activation of dynein in the axon initial segment regulates polarized cargo transport in neurons. Traffic (Copenhagen, Denmark). PMID 28941293 DOI: 10.1111/tra.12529  0.8
2017 Guedes-Dias P, Holzbaur ELF. Huntingtin Fibrils Poke Membranes. Cell. 171: 32-33. PMID 28938121 DOI: 10.1016/j.cell.2017.09.009  0.56
2017 Nirschl JJ, Ghiretti AE, Holzbaur ELF. The impact of cytoskeletal organization on the local regulation of neuronal transport. Nature Reviews. Neuroscience. PMID 28855741 DOI: 10.1038/nrn.2017.100  1
2017 Ayloo S, Guedes-Dias P, Ghiretti AE, Holzbaur ELF. Dynein efficiently navigates the dendritic cytoskeleton to drive the retrograde trafficking of BDNF/TrkB signaling endosomes. Molecular Biology of the Cell. PMID 28720664 DOI: 10.1091/mbc.E17-01-0068  0.96
2017 Lippert LG, Dadosh T, Hadden JA, Karnawat V, Diroll BT, Murray CB, Holzbaur ELF, Schulten K, Reck-Peterson SL, Goldman YE. Angular measurements of the dynein ring reveal a stepping mechanism dependent on a flexible stalk. Proceedings of the National Academy of Sciences of the United States of America. PMID 28533393 DOI: 10.1073/pnas.1620149114  0.84
2017 Gopal PP, Nirschl JJ, Klinman E, Holzbaur EL. Amyotrophic lateral sclerosis-linked mutations increase the viscosity of liquid-like TDP-43 RNP granules in neurons. Proceedings of the National Academy of Sciences of the United States of America. PMID 28265061 DOI: 10.1073/pnas.1614462114  1
2016 Ghiretti AE, Thies E, Tokito MK, Lin T, Ostap EM, Kneussel M, Holzbaur EL. Activity-Dependent Regulation of Distinct Transport and Cytoskeletal Remodeling Functions of the Dendritic Kinesin KIF21B. Neuron. PMID 27817978 DOI: 10.1016/j.neuron.2016.10.003  0.96
2016 Moore AS, Wong YC, Simpson CL, Holzbaur EL. Dynamic actin cycling through mitochondrial subpopulations locally regulates the fission-fusion balance within mitochondrial networks. Nature Communications. 7: 12886. PMID 27686185 DOI: 10.1038/ncomms12886  0.76
2016 Moore AS, Holzbaur EL. Spatiotemporal dynamics of autophagy receptors in selective mitophagy. Autophagy. 0. PMID 27484150 DOI: 10.1080/15548627.2016.1212788  0.76
2016 Olenick MA, Tokito M, Boczkowska M, Dominguez R, Holzbaur EL. Hook Adaptors Induce Unidirectional Processive Motility by Enhancing the Dynein-Dynactin Interaction. The Journal of Biological Chemistry. PMID 27365401 DOI: 10.1074/jbc.M116.738211  0.8
2016 Maday S, Holzbaur EL. Compartment-Specific Regulation of Autophagy in Primary Neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 5933-45. PMID 27251616 DOI: 10.1523/JNEUROSCI.4401-15.2016  0.84
2016 Moore AS, Holzbaur EL. Dynamic recruitment and activation of ALS-associated TBK1 with its target optineurin are required for efficient mitophagy. Proceedings of the National Academy of Sciences of the United States of America. PMID 27247382 DOI: 10.1073/pnas.1523810113  1
2016 Twelvetrees AE, Pernigo S, Sanger A, Guedes-Dias P, Schiavo G, Steiner RA, Dodding MP, Holzbaur EL. The Dynamic Localization of Cytoplasmic Dynein in Neurons Is Driven by Kinesin-1. Neuron. PMID 27210554 DOI: 10.1016/j.neuron.2016.04.046  1
2016 Muhia M, Thies E, Labonté D, Ghiretti AE, Gromova KV, Xompero F, Lappe-Siefke C, Hermans-Borgmeyer I, Kuhl D, Schweizer M, Ohana O, Schwarz JR, Holzbaur EL, Kneussel M. The Kinesin KIF21B Regulates Microtubule Dynamics and Is Essential for Neuronal Morphology, Synapse Function, and Learning and Memory. Cell Reports. PMID 27117409 DOI: 10.1016/j.celrep.2016.03.086  0.96
2016 Nirschl JJ, Ghiretti AE, Holzbaur EL. Lipid Rafts Assemble Dynein Ensembles. Trends in Biochemical Sciences. PMID 27061495 DOI: 10.1016/j.tibs.2016.03.005  1
2016 Nirschl JJ, Magiera MM, Lazarus JE, Janke C, Holzbaur EL. α-Tubulin Tyrosination and CLIP-170 Phosphorylation Regulate the Initiation of Dynein-Driven Transport in Neurons. Cell Reports. PMID 26972003 DOI: 10.1016/j.celrep.2016.02.046  1
2016 Klinman E, Holzbaur EL. Comparative analysis of axonal transport markers in primary mammalian neurons. Methods in Cell Biology. 131: 409-24. PMID 26794526 DOI: 10.1016/bs.mcb.2015.06.011  1
2016 Nirschl JJ, Holzbaur EL. Live-cell imaging of retrograde transport initiation in primary neurons. Methods in Cell Biology. 131: 269-76. PMID 26794519 DOI: 10.1016/bs.mcb.2015.06.002  1
2015 Klinman E, Holzbaur EL. Stress-Induced CDK5 Activation Disrupts Axonal Transport via Lis1/Ndel1/Dynein. Cell Reports. 12: 462-73. PMID 26166569 DOI: 10.1016/j.celrep.2015.06.032  1
2015 Kast DJ, Zajac AL, Holzbaur EL, Ostap EM, Dominguez R. WHAMM Directs the Arp2/3 Complex to the ER for Autophagosome Biogenesis through an Actin Comet Tail Mechanism. Current Biology : Cb. 25: 1791-7. PMID 26096974 DOI: 10.1016/j.cub.2015.05.042  0.76
2015 Ayloo S, Holzbaur EL. Reconstitution of microtubule-based motility using cell extracts. Methods in Cell Biology. 128: 57-68. PMID 25997342 DOI: 10.1016/bs.mcb.2015.02.002  1
2015 Ballister ER, Ayloo S, Chenoweth DM, Lampson MA, Holzbaur EL. Optogenetic control of organelle transport using a photocaged chemical inducer of dimerization. Current Biology : Cb. 25: R407-8. PMID 25989077 DOI: 10.1016/j.cub.2015.03.056  1
2015 Wong YC, Holzbaur EL. Autophagosome dynamics in neurodegeneration at a glance. Journal of Cell Science. 128: 1259-67. PMID 25829512 DOI: 10.1242/jcs.161216  1
2015 Wong YC, Holzbaur EL. Temporal dynamics of PARK2/parkin and OPTN/optineurin recruitment during the mitophagy of damaged mitochondria. Autophagy. 11: 422-4. PMID 25801386 DOI: 10.1080/15548627.2015.1009792  1
2015 McIntosh BB, Holzbaur EL, Ostap EM. Control of the initiation and termination of kinesin-1-driven transport by myosin-Ic and nonmuscle tropomyosin. Current Biology : Cb. 25: 523-9. PMID 25660542 DOI: 10.1016/j.cub.2014.12.008  1
2015 Wilson MH, Holzbaur EL. Nesprins anchor kinesin-1 motors to the nucleus to drive nuclear distribution in muscle cells. Development (Cambridge, England). 142: 218-28. PMID 25516977 DOI: 10.1242/dev.114769  1
2015 Kast DJ, Zajac AL, Holzbaur ELF, Ostap EM, Dominguez R. WHAMM Directs the Arp2/3 Complex to the ER for Autophagosome Biogenesis through an Actin Comet Tail Mechanism Current Biology. DOI: 10.1016/j.cub.2015.05.042  1
2014 Fu MM, Holzbaur EL. MAPK8IP1/JIP1 regulates the trafficking of autophagosomes in neurons. Autophagy. 10: 2079-81. PMID 25483967 DOI: 10.4161/auto.34451  1
2014 Maday S, Twelvetrees AE, Moughamian AJ, Holzbaur EL. Axonal transport: cargo-specific mechanisms of motility and regulation. Neuron. 84: 292-309. PMID 25374356 DOI: 10.1016/j.neuron.2014.10.019  1
2014 Mantegazza AR, Zajac AL, Twelvetrees A, Holzbaur EL, Amigorena S, Marks MS. TLR-dependent phagosome tubulation in dendritic cells promotes phagosome cross-talk to optimize MHC-II antigen presentation. Proceedings of the National Academy of Sciences of the United States of America. 111: 15508-13. PMID 25313083 DOI: 10.1073/pnas.1412998111  1
2014 Wong YC, Holzbaur EL. Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation. Proceedings of the National Academy of Sciences of the United States of America. 111: E4439-48. PMID 25294927 DOI: 10.1073/pnas.1405752111  1
2014 Thom CS, Traxler EA, Khandros E, Nickas JM, Zhou OY, Lazarus JE, Silva AP, Prabhu D, Yao Y, Aribeana C, Fuchs SY, Mackay JP, Holzbaur EL, Weiss MJ. Trim58 degrades Dynein and regulates terminal erythropoiesis. Developmental Cell. 30: 688-700. PMID 25241935 DOI: 10.1016/j.devcel.2014.07.021  1
2014 Ayloo S, Lazarus JE, Dodda A, Tokito M, Ostap EM, Holzbaur EL. Dynactin functions as both a dynamic tether and brake during dynein-driven motility. Nature Communications. 5: 4807. PMID 25185702 DOI: 10.1038/ncomms5807  1
2014 Maday S, Holzbaur EL. Autophagosome biogenesis in primary neurons follows an ordered and spatially regulated pathway. Developmental Cell. 30: 71-85. PMID 25026034 DOI: 10.1016/j.devcel.2014.06.001  1
2014 De La Cruz EM, Holzbaur EL. Navigating the cell: how motors function in vivo. Journal of Cell Science. 127: 2997-8. PMID 25024456 DOI: 10.1242/jcs.156414  1
2014 Fu MM, Holzbaur EL. Integrated regulation of motor-driven organelle transport by scaffolding proteins. Trends in Cell Biology. 24: 564-74. PMID 24953741 DOI: 10.1016/j.tcb.2014.05.002  1
2014 Fu MM, Nirschl JJ, Holzbaur EL. LC3 binding to the scaffolding protein JIP1 regulates processive dynein-driven transport of autophagosomes. Developmental Cell. 29: 577-90. PMID 24914561 DOI: 10.1016/j.devcel.2014.04.015  0.92
2014 Castle MJ, Gershenson ZT, Giles AR, Holzbaur EL, Wolfe JH. Adeno-associated virus serotypes 1, 8, and 9 share conserved mechanisms for anterograde and retrograde axonal transport. Human Gene Therapy. 25: 705-20. PMID 24694006 DOI: 10.1089/hum.2013.189  1
2014 Hendricks AG, Goldman YE, Holzbaur EL. Reconstituting the motility of isolated intracellular cargoes. Methods in Enzymology. 540: 249-62. PMID 24630111 DOI: 10.1016/B978-0-12-397924-7.00014-5  1
2014 Wong YC, Holzbaur EL. The regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 1293-305. PMID 24453320 DOI: 10.1523/JNEUROSCI.1870-13.2014  1
2014 Castle MJ, Perlson E, Holzbaur EL, Wolfe JH. Long-distance axonal transport of AAV9 is driven by dynein and kinesin-2 and is trafficked in a highly motile Rab7-positive compartment. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 554-66. PMID 24100640 DOI: 10.1038/mt.2013.237  1
2013 Drivas TG, Holzbaur EL, Bennett J. Disruption of CEP290 microtubule/membrane-binding domains causes retinal degeneration. The Journal of Clinical Investigation. 123: 4525-39. PMID 24051377 DOI: 10.1172/JCI69448  1
2013 Perlson E, Hendricks AG, Lazarus JE, Ben-Yaakov K, Gradus T, Tokito M, Holzbaur EL. Dynein interacts with the neural cell adhesion molecule (NCAM180) to tether dynamic microtubules and maintain synaptic density in cortical neurons. The Journal of Biological Chemistry. 288: 27812-24. PMID 23960070 DOI: 10.1074/jbc.M113.465088  1
2013 Moughamian AJ, Osborn GE, Lazarus JE, Maday S, Holzbaur EL. Ordered recruitment of dynactin to the microtubule plus-end is required for efficient initiation of retrograde axonal transport. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 13190-203. PMID 23926272 DOI: 10.1523/JNEUROSCI.0935-13.2013  1
2013 Fu MM, Holzbaur EL. JIP1 regulates the directionality of APP axonal transport by coordinating kinesin and dynein motors. The Journal of Cell Biology. 202: 495-508. PMID 23897889 DOI: 10.1083/jcb.201302078  1
2013 Lazarus JE, Moughamian AJ, Tokito MK, Holzbaur EL. Dynactin subunit p150(Glued) is a neuron-specific anti-catastrophe factor. Plos Biology. 11: e1001611. PMID 23874158 DOI: 10.1371/journal.pbio.1001611  1
2013 Zajac AL, Goldman YE, Holzbaur EL, Ostap EM. Local cytoskeletal and organelle interactions impact molecular-motor- driven early endosomal trafficking. Current Biology : Cb. 23: 1173-80. PMID 23770188 DOI: 10.1016/j.cub.2013.05.015  1
2013 Zhang J, Twelvetrees AE, Lazarus JE, Blasier KR, Yao X, Inamdar NA, Holzbaur EL, Pfister KK, Xiang X. Establishing a novel knock-in mouse line for studying neuronal cytoplasmic dynein under normal and pathologic conditions. Cytoskeleton (Hoboken, N.J.). 70: 215-27. PMID 23475693 DOI: 10.1002/cm.21102  1
2012 Hendricks AG, Twelvetrees AE, Holzbaur EL. Intracellular transport: new tools provide insights into multi-motor transport. Current Biology : Cb. 22: R1053-5. PMID 23257193 DOI: 10.1016/j.cub.2012.11.009  1
2012 Hendricks AG, Holzbaur EL, Goldman YE. Force measurements on cargoes in living cells reveal collective dynamics of microtubule motors. Proceedings of the National Academy of Sciences of the United States of America. 109: 18447-52. PMID 23091040 DOI: 10.1073/pnas.1215462109  1
2012 Schroeder HW, Hendricks AG, Ikeda K, Shuman H, Rodionov V, Ikebe M, Goldman YE, Holzbaur EL. Force-dependent detachment of kinesin-2 biases track switching at cytoskeletal filament intersections. Biophysical Journal. 103: 48-58. PMID 22828331 DOI: 10.1016/j.bpj.2012.05.037  1
2012 Wilson MH, Holzbaur EL. Opposing microtubule motors drive robust nuclear dynamics in developing muscle cells. Journal of Cell Science. 125: 4158-69. PMID 22623723 DOI: 10.1242/jcs.108688  1
2012 Maday S, Holzbaur EL. Autophagosome assembly and cargo capture in the distal axon. Autophagy. 8: 858-60. PMID 22617438 DOI: 10.4161/auto.20055  1
2012 Twelvetrees A, Hendricks AG, Holzbaur EL. SnapShot: axonal transport. Cell. 149: 950-950.e1. PMID 22579292 DOI: 10.1016/j.cell.2012.05.001  1
2012 Moughamian AJ, Holzbaur EL. Dynactin is required for transport initiation from the distal axon. Neuron. 74: 331-43. PMID 22542186 DOI: 10.1016/j.neuron.2012.02.025  1
2012 Hendricks AG, Lazarus JE, Perlson E, Gardner MK, Odde DJ, Goldman YE, Holzbaur EL. Dynein tethers and stabilizes dynamic microtubule plus ends. Current Biology : Cb. 22: 632-7. PMID 22445300 DOI: 10.1016/j.cub.2012.02.023  1
2012 Moughamian AJ, Holzbaur EL. Synaptic vesicle distribution by conveyor belt. Cell. 148: 849-51. PMID 22385955 DOI: 10.1016/j.cell.2012.02.007  1
2012 Maday S, Wallace KE, Holzbaur EL. Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons. The Journal of Cell Biology. 196: 407-17. PMID 22331844 DOI: 10.1083/jcb.201106120  1
2012 Moughamian AJ, Holzbaur ELF. Cytoplasmic dynein dysfunction and neurodegenerative disease Dyneins. 584-601. DOI: 10.1016/B978-0-12-382004-4.10023-8  1
2011 Holzbaur EL, Scherer SS. Microtubules, axonal transport, and neuropathy. The New England Journal of Medicine. 365: 2330-2. PMID 22168648 DOI: 10.1056/NEJMcibr1112481  1
2011 Heisler FF, Loebrich S, Pechmann Y, Maier N, Zivkovic AR, Tokito M, Hausrat TJ, Schweizer M, Bähring R, Holzbaur EL, Schmitz D, Kneussel M. Muskelin regulates actin filament- and microtubule-based GABA(A) receptor transport in neurons. Neuron. 70: 66-81. PMID 21482357 DOI: 10.1016/j.neuron.2011.03.008  1
2011 Caviston JP, Zajac AL, Tokito M, Holzbaur EL. Huntingtin coordinates the dynein-mediated dynamic positioning of endosomes and lysosomes. Molecular Biology of the Cell. 22: 478-92. PMID 21169558 DOI: 10.1091/mbc.E10-03-0233  1
2010 Hendricks AG, Lazarus JE, Holzbaur EL. Dynein at odd angles? Nature Cell Biology. 12: 1126-8. PMID 21102436 DOI: 10.1038/ncb1210-1126  1
2010 Schapitz IU, Behrend B, Pechmann Y, Lappe-Siefke C, Kneussel SJ, Wallace KE, Stempel AV, Buck F, Grant SG, Schweizer M, Schmitz D, Schwarz JR, Holzbaur EL, Kneussel M. Neuroligin 1 is dynamically exchanged at postsynaptic sites. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 12733-44. PMID 20861378 DOI: 10.1523/JNEUROSCI.0896-10.2010  1
2010 Holzbaur E. Axonal transport: CDKs as traffic signals for motor-ists along the axon? Current Biology : Cb. 20: R641-2. PMID 20692613 DOI: 10.1016/j.cub.2010.06.016  1
2010 Mentlik AN, Sanborn KB, Holzbaur EL, Orange JS. Rapid lytic granule convergence to the MTOC in natural killer cells is dependent on dynein but not cytolytic commitment. Molecular Biology of the Cell. 21: 2241-56. PMID 20444980 DOI: 10.1091/mbc.E09-11-0930  1
2010 Perlson E, Maday S, Fu MM, Moughamian AJ, Holzbaur EL. Retrograde axonal transport: pathways to cell death? Trends in Neurosciences. 33: 335-44. PMID 20434225 DOI: 10.1016/j.tins.2010.03.006  1
2010 Hendricks AG, Perlson E, Ross JL, Schroeder HW, Tokito M, Holzbaur EL. Motor coordination via a tug-of-war mechanism drives bidirectional vesicle transport. Current Biology : Cb. 20: 697-702. PMID 20399099 DOI: 10.1016/j.cub.2010.02.058  1
2010 Schroeder HW, Mitchell C, Shuman H, Holzbaur EL, Goldman YE. Motor number controls cargo switching at actin-microtubule intersections in vitro. Current Biology : Cb. 20: 687-96. PMID 20399098 DOI: 10.1016/j.cub.2010.03.024  1
2010 Holzbaur EL, Goldman YE. Coordination of molecular motors: from in vitro assays to intracellular dynamics. Current Opinion in Cell Biology. 22: 4-13. PMID 20102789 DOI: 10.1016/  1
2010 Holzbaur ELF. Axonal Transport and ALS Encyclopedia of Neuroscience. 1181-1187. DOI: 10.1016/B978-008045046-9.00711-7  1
2009 Perlson E, Jeong GB, Ross JL, Dixit R, Wallace KE, Kalb RG, Holzbaur EL. A switch in retrograde signaling from survival to stress in rapid-onset neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 9903-17. PMID 19657041 DOI: 10.1523/JNEUROSCI.0813-09.2009  1
2009 Caviston JP, Holzbaur EL. Huntingtin as an essential integrator of intracellular vesicular trafficking. Trends in Cell Biology. 19: 147-55. PMID 19269181 DOI: 10.1016/j.tcb.2009.01.005  1
2009 Dixit R, Barnett B, Lazarus JE, Tokito M, Goldman YE, Holzbaur EL. Microtubule plus-end tracking by CLIP-170 requires EB1. Proceedings of the National Academy of Sciences of the United States of America. 106: 492-7. PMID 19126680 DOI: 10.1073/pnas.0807614106  1
2008 Perlson E, Holzbaur EL. Myosin learns to recruit AMPA receptors. Cell. 135: 414-5. PMID 18984153 DOI: 10.1016/j.cell.2008.10.013  1
2008 Dixit R, Levy JR, Tokito M, Ligon LA, Holzbaur EL. Regulation of dynactin through the differential expression of p150Glued isoforms. The Journal of Biological Chemistry. 283: 33611-9. PMID 18812314 DOI: 10.1074/jbc.M804840200  1
2008 Levy JR, Holzbaur EL. Dynein drives nuclear rotation during forward progression of motile fibroblasts. Journal of Cell Science. 121: 3187-95. PMID 18782860 DOI: 10.1242/jcs.033878  1
2008 Chevalier-Larsen ES, Wallace KE, Pennise CR, Holzbaur EL. Lysosomal proliferation and distal degeneration in motor neurons expressing the G59S mutation in the p150Glued subunit of dynactin. Human Molecular Genetics. 17: 1946-55. PMID 18364389 DOI: 10.1093/hmg/ddn092  1
2008 Ross JL, Shuman H, Holzbaur EL, Goldman YE. Kinesin and dynein-dynactin at intersecting microtubules: motor density affects dynein function. Biophysical Journal. 94: 3115-25. PMID 18227130 DOI: 10.1529/biophysj.107.120014  1
2008 Dixit R, Ross JL, Goldman YE, Holzbaur EL. Differential regulation of dynein and kinesin motor proteins by tau. Science (New York, N.Y.). 319: 1086-9. PMID 18202255 DOI: 10.1126/science.1152993  1
2007 Ligon LA, Holzbaur EL. Microtubules tethered at epithelial cell junctions by dynein facilitate efficient junction assembly. Traffic (Copenhagen, Denmark). 8: 808-19. PMID 17550375 DOI: 10.1111/j.1600-0854.2007.00574.x  1
2007 Caviston JP, Ross JL, Antony SM, Tokito M, Holzbaur EL. Huntingtin facilitates dynein/dynactin-mediated vesicle transport. Proceedings of the National Academy of Sciences of the United States of America. 104: 10045-50. PMID 17548833 DOI: 10.1073/pnas.0610628104  1
2007 Levy JR, Holzbaur EL. Special delivery: dynamic targeting via cortical capture of microtubules. Developmental Cell. 12: 320-2. PMID 17336896 DOI: 10.1016/j.devcel.2007.02.012  1
2007 Perlson E, Holzbaur ELF. The Role of Molecular Motors in Axonal Transport Protein Trafficking in Neurons. 29-43. DOI: 10.1016/B978-012369437-9/50004-9  1
2006 Combs J, Kim SJ, Tan S, Ligon LA, Holzbaur EL, Kuhn J, Poenie M. Recruitment of dynein to the Jurkat immunological synapse. Proceedings of the National Academy of Sciences of the United States of America. 103: 14883-8. PMID 16990435 DOI: 10.1073/pnas.0600914103  1
2006 Caviston JP, Holzbaur EL. Microtubule motors at the intersection of trafficking and transport. Trends in Cell Biology. 16: 530-7. PMID 16938456 DOI: 10.1016/j.tcb.2006.08.002  1
2006 Holzbaur EL, Howland DS, Weber N, Wallace K, She Y, Kwak S, Tchistiakova LA, Murphy E, Hinson J, Karim R, Tan XY, Kelley P, McGill KC, Williams G, Hobbs C, et al. Myostatin inhibition slows muscle atrophy in rodent models of amyotrophic lateral sclerosis. Neurobiology of Disease. 23: 697-707. PMID 16837207 DOI: 10.1016/j.nbd.2006.05.009  1
2006 Chevalier-Larsen E, Holzbaur EL. Axonal transport and neurodegenerative disease. Biochimica Et Biophysica Acta. 1762: 1094-108. PMID 16730956 DOI: 10.1016/j.bbadis.2006.04.002  1
2006 Ross JL, Wallace K, Shuman H, Goldman YE, Holzbaur EL. Processive bidirectional motion of dynein-dynactin complexes in vitro. Nature Cell Biology. 8: 562-70. PMID 16715075 DOI: 10.1038/ncb1421  1
2006 Levy JR, Sumner CJ, Caviston JP, Tokito MK, Ranganathan S, Ligon LA, Wallace KE, LaMonte BH, Harmison GG, Puls I, Fischbeck KH, Holzbaur EL. A motor neuron disease-associated mutation in p150Glued perturbs dynactin function and induces protein aggregation. The Journal of Cell Biology. 172: 733-45. PMID 16505168 DOI: 10.1083/jcb.200511068  1
2006 Ligon LA, Shelly SS, Tokito MK, Holzbaur EL. Microtubule binding proteins CLIP-170, EB1, and p150Glued form distinct plus-end complexes. Febs Letters. 580: 1327-32. PMID 16455083 DOI: 10.1016/j.febslet.2006.01.050  1
2006 Levy JR, Holzbaur EL. Cytoplasmic dynein/dynactin function and dysfunction in motor neurons. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 24: 103-11. PMID 16406469 DOI: 10.1016/j.ijdevneu.2005.11.013  1
2005 Pfister KK, Fisher EM, Gibbons IR, Hays TS, Holzbaur EL, McIntosh JR, Porter ME, Schroer TA, Vaughan KT, Witman GB, King SM, Vallee RB. Cytoplasmic dynein nomenclature. The Journal of Cell Biology. 171: 411-3. PMID 16260502 DOI: 10.1083/jcb.200508078  1
2005 Yoshino A, Setty SR, Poynton C, Whiteman EL, Saint-Pol A, Burd CG, Johannes L, Holzbaur EL, Koval M, McCaffery JM, Marks MS. tGolgin-1 (p230, golgin-245) modulates Shiga-toxin transport to the Golgi and Golgi motility towards the microtubule-organizing centre. Journal of Cell Science. 118: 2279-93. PMID 15870108 DOI: 10.1242/jcs.02358  1
2005 Puls I, Oh SJ, Sumner CJ, Wallace KE, Floeter MK, Mann EA, Kennedy WR, Wendelschafer-Crabb G, Vortmeyer A, Powers R, Finnegan K, Holzbaur EL, Fischbeck KH, Ludlow CL. Distal spinal and bulbar muscular atrophy caused by dynactin mutation. Annals of Neurology. 57: 687-94. PMID 15852399 DOI: 10.1002/ana.20468  1
2005 Ligon LA, LaMonte BH, Wallace KE, Weber N, Kalb RG, Holzbaur EL. Mutant superoxide dismutase disrupts cytoplasmic dynein in motor neurons. Neuroreport. 16: 533-6. PMID 15812301 DOI: 10.1097/00001756-200504250-00002  1
2004 Wagner OI, Ascaño J, Tokito M, Leterrier JF, Janmey PA, Holzbaur EL. The interaction of neurofilaments with the microtubule motor cytoplasmic dynein. Molecular Biology of the Cell. 15: 5092-100. PMID 15342782 DOI: 10.1091/mbc.E04-05-0401  1
2004 Holzbaur EL. Tangled NUDELs? Nature Cell Biology. 6: 569-70. PMID 15232582 DOI: 10.1038/ncb0704-569  1
2004 Holzbaur EL. Motor neurons rely on motor proteins. Trends in Cell Biology. 14: 233-40. PMID 15130579 DOI: 10.1016/j.tcb.2004.03.009  1
2004 Ligon LA, Tokito M, Finklestein JM, Grossman FE, Holzbaur EL. A direct interaction between cytoplasmic dynein and kinesin I may coordinate motor activity. The Journal of Biological Chemistry. 279: 19201-8. PMID 14985359 DOI: 10.1074/jbc.M313472200  1
2003 Ligon LA, Shelly SS, Tokito M, Holzbaur EL. The microtubule plus-end proteins EB1 and dynactin have differential effects on microtubule polymerization. Molecular Biology of the Cell. 14: 1405-17. PMID 12686597 DOI: 10.1091/mbc.E02-03-0155  1
2003 Puls I, Jonnakuty C, LaMonte BH, Holzbaur EL, Tokito M, Mann E, Floeter MK, Bidus K, Drayna D, Oh SJ, Brown RH, Ludlow CL, Fischbeck KH. Mutant dynactin in motor neuron disease. Nature Genetics. 33: 455-6. PMID 12627231 DOI: 10.1038/ng1123  1
2002 LaMonte BH, Wallace KE, Holloway BA, Shelly SS, Ascaño J, Tokito M, Van Winkle T, Howland DS, Holzbaur EL. Disruption of dynein/dynactin inhibits axonal transport in motor neurons causing late-onset progressive degeneration. Neuron. 34: 715-27. PMID 12062019 DOI: 10.1016/S0896-6273(02)00696-7  1
2002 Karki S, Ligon LA, DeSantis J, Tokito M, Holzbaur EL. PLAC-24 is a cytoplasmic dynein-binding protein that is recruited to sites of cell-cell contact. Molecular Biology of the Cell. 13: 1722-34. PMID 12006665 DOI: 10.1091/mbc.02-02-0011  1
2002 Andersen OS. The 55th Annual Meeting and Symposium of the Society of General Physiologists: molecular motors. The Journal of General Physiology. 119: 117-22. PMID 11815661 DOI: 10.1085/jgp.119.2.117  1
2001 Ligon LA, Karki S, Tokito M, Holzbaur EL. Dynein binds to beta-catenin and may tether microtubules at adherens junctions. Nature Cell Biology. 3: 913-7. PMID 11584273 DOI: 10.1038/ncb1001-913  1
2001 Holleran EA, Ligon LA, Tokito M, Stankewich MC, Morrow JS, Holzbaur EL. beta III spectrin binds to the Arp1 subunit of dynactin. The Journal of Biological Chemistry. 276: 36598-605. PMID 11461920 DOI: 10.1074/jbc.M104838200  1
2001 Muresan V, Stankewich MC, Steffen W, Morrow JS, Holzbaur EL, Schnapp BJ. Dynactin-dependent, dynein-driven vesicle transport in the absence of membrane proteins: a role for spectrin and acidic phospholipids. Molecular Cell. 7: 173-83. PMID 11172722 DOI: 10.1016/S1097-2765(01)00165-4  1
2000 Karki S, Tokito MK, Holzbaur EL. A dynactin subunit with a highly conserved cysteine-rich motif interacts directly with Arp1. The Journal of Biological Chemistry. 275: 4834-9. PMID 10671518 DOI: 10.1074/jbc.275.7.4834  1
1999 Karki S, Holzbaur EL. Cytoplasmic dynein and dynactin in cell division and intracellular transport. Current Opinion in Cell Biology. 11: 45-53. PMID 10047518 DOI: 10.1016/S0955-0674(99)80006-4  1
1998 Tokito MK, Holzbaur EL. The genomic structure of DCTN1, a candidate gene for limb-girdle muscular dystrophy (LGMD2B). Biochimica Et Biophysica Acta. 1442: 432-6. PMID 9805007 DOI: 10.1016/S0167-4781(98)00195-X  1
1998 Karki S, LaMonte B, Holzbaur EL. Characterization of the p22 subunit of dynactin reveals the localization of cytoplasmic dynein and dynactin to the midbody of dividing cells. The Journal of Cell Biology. 142: 1023-34. PMID 9722614 DOI: 10.1083/jcb.142.4.1023  1
1998 Holleran EA, Holzbaur EL. Speculating about spectrin: new insights into the Golgi-associated cytoskeleton. Trends in Cell Biology. 8: 26-9. PMID 9695804 DOI: 10.1016/S0962-8924(97)01195-1  1
1998 Holleran EA, Karki S, Holzbaur EL. The role of the dynactin complex in intracellular motility. International Review of Cytology. 182: 69-109. PMID 9522459  1
1997 Engelender S, Sharp AH, Colomer V, Tokito MK, Lanahan A, Worley P, Holzbaur EL, Ross CA. Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin. Human Molecular Genetics. 6: 2205-12. PMID 9361024 DOI: 10.1093/HMG/6.13.2205  1
1997 Steffen W, Karki S, Vaughan KT, Vallee RB, Holzbaur EL, Weiss DG, Kuznetsov SA. The involvement of the intermediate chain of cytoplasmic dynein in binding the motor complex to membranous organelles of Xenopus oocytes. Molecular Biology of the Cell. 8: 2077-88. PMID 9348543  1
1997 Waterman-Storer CM, Karki SB, Kuznetsov SA, Tabb JS, Weiss DG, Langford GM, Holzbaur EL. The interaction between cytoplasmic dynein and dynactin is required for fast axonal transport. Proceedings of the National Academy of Sciences of the United States of America. 94: 12180-5. PMID 9342383 DOI: 10.1073/pnas.94.22.12180  1
1997 Farshori P, Holzbaur EL. Dynactin phosphorylation is modulated in response to cellular effectors. Biochemical and Biophysical Research Communications. 232: 810-6. PMID 9126359 DOI: 10.1006/bbrc.1997.6379  1
1997 Jang W, Weber JS, Tokito MK, Holzbaur EL, Meisler MH. Mouse p150Glued (dynactin 1) cDNA sequence and evaluation as a candidate for the neuromuscular disease mutation mnd2. Biochemical and Biophysical Research Communications. 231: 344-7. PMID 9070275 DOI: 10.1006/bbrc.1997.6095  1
1997 Karki S, Tokito MK, Holzbaur EL. Casein kinase II binds to and phosphorylates cytoplasmic dynein. The Journal of Biological Chemistry. 272: 5887-91. PMID 9038206 DOI: 10.1074/jbc.272.9.5887  1
1997 Holleran E, Holzbaur E. Pictures in cell biology. Does centractin/Arp1 link dynactin to membranes? Trends in Cell Biology. 7: 192.  1
1996 Holleran EA, Tokito MK, Karki S, Holzbaur EL. Centractin (ARP1) associates with spectrin revealing a potential mechanism to link dynactin to intracellular organelles. The Journal of Cell Biology. 135: 1815-29. PMID 8991093 DOI: 10.1083/jcb.135.6.1815  1
1996 Tokito MK, Howland DS, Lee VM, Holzbaur EL. Functionally distinct isoforms of dynactin are expressed in human neurons. Molecular Biology of the Cell. 7: 1167-80. PMID 8856662  1
1996 Holzbaur EL, Tokito MK. Localization of the DCTN1 gene encoding p150Glued to human chromosome 2p13 by fluorescence in situ hybridization. Genomics. 31: 398-9. PMID 8838327 DOI: 10.1006/geno.1996.0068  1
1996 Dillman JF, Dabney LP, Karki S, Paschal BM, Holzbaur EL, Pfister KK. Functional analysis of dynactin and cytoplasmic dynein in slow axonal transport. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 6742-52. PMID 8824315  1
1996 Sweeney HL, Holzbaur EL. Mutational analysis of motor proteins. Annual Review of Physiology. 58: 751-92. PMID 8815819 DOI: 10.1146/  1
1996 Vaughan KT, Mikami A, Paschal BM, Holzbaur EL, Hughes SM, Echeverri CJ, Moore KJ, Gilbert DJ, Copeland NG, Jenkins NA, Vallee RB. Multiple mouse chromosomal loci for dynein-based motility. Genomics. 36: 29-38. PMID 8812413 DOI: 10.1006/geno.1996.0422  1
1996 Waterman-Storer CM, Holzbaur EL. The product of the Drosophila gene, Glued, is the functional homologue of the p150Glued component of the vertebrate dynactin complex. The Journal of Biological Chemistry. 271: 1153-9. PMID 8557644  1
1995 Waterman-Storer CM, Karki S, Holzbaur EL. The p150Glued component of the dynactin complex binds to both microtubules and the actin-related protein centractin (Arp-1). Proceedings of the National Academy of Sciences of the United States of America. 92: 1634-8. PMID 7878030  1
1995 Vaughan KT, Holzbaur EL, Vallee RB. Subcellular targeting of the retrograde motor cytoplasmic dynein. Biochemical Society Transactions. 23: 50-4. PMID 7758764  1
1995 Melloni RH, Tokito MK, Holzbaur EL. Expression of the p150Glued component of the dynactin complex in developing and adult rat brain. The Journal of Comparative Neurology. 357: 15-24. PMID 7673464 DOI: 10.1002/cne.903570103  1
1995 Karki S, Holzbaur EL. Affinity chromatography demonstrates a direct binding between cytoplasmic dynein and the dynactin complex. The Journal of Biological Chemistry. 270: 28806-11. PMID 7499404 DOI: 10.1074/jbc.270.48.28806  1
1994 Holzbaur EL, Vallee RB. DYNEINS: molecular structure and cellular function. Annual Review of Cell Biology. 10: 339-72. PMID 7888180 DOI: 10.1146/annurev.cb.10.110194.002011  1
1994 Clark SW, Staub O, Clark IB, Holzbaur EL, Paschal BM, Vallee RB, Meyer DI. Beta-centractin: characterization and distribution of a new member of the centractin family of actin-related proteins. Molecular Biology of the Cell. 5: 1301-10. PMID 7696711  1
1993 Paschal BM, Holzbaur EL, Pfister KK, Clark S, Meyer DI, Vallee RB. Characterization of a 50-kDa polypeptide in cytoplasmic dynein preparations reveals a complex with p150GLUED and a novel actin. The Journal of Biological Chemistry. 268: 15318-23. PMID 8325901  1
1993 Obar RA, Holzbaur EL. Immunoselection and characterization of cDNA clones. Methods in Cell Biology. 37: 361-405. PMID 8255249 DOI: 10.1016/S0091-679X(08)60258-7  1
1992 Holzbaur EL, Hammarback JA, Paschal BM, Kravit NG, Pfister KK, Vallee RB. Homology of a 150K cytoplasmic dynein-associated polypeptide with the Drosophila gene Glued. Nature. 360: 695. PMID 1361213 DOI: 10.1038/360695a0  0.6
1991 Holzbaur EL, Hammarback JA, Paschal BM, Kravit NG, Pfister KK, Vallee RB. Homology of a 150K cytoplasmic dynein-associated polypeptide with the Drosophila gene Glued. Nature. 351: 579-83. PMID 1828535 DOI: 10.1038/351579a0  1
1989 Holzbaur EL, Johnson KA. Microtubules accelerate ADP release by dynein. Biochemistry. 28: 7010-6. PMID 2531005 DOI: 10.1021/BI00443A034  1
1989 Holzbaur EL, Johnson KA. ADP release is rate limiting in steady-state turnover by the dynein adenosinetriphosphatase. Biochemistry. 28: 5577-85. PMID 2528374 DOI: 10.1021/BI00439A036  1
1989 Andrawis A, Pease EA, Kuan IC, Holzbaur E, Tien M. Characterization of two lignin peroxidase clones from Phanerochaete chrysosporium. Biochemical and Biophysical Research Communications. 162: 673-80. PMID 2474293 DOI: 10.1016/0006-291X(89)92363-2  1
1988 Holzbaur EL, Andrawis A, Tien M. Structure and regulation of a lignin peroxidase gene from Phanerochaete chrysosporium. Biochemical and Biophysical Research Communications. 155: 626-33. PMID 2844176 DOI: 10.1016/S0006-291X(88)80541-2  1
1986 Johnson KA, Marchese-Ragona SP, Clutter DB, Holzbaur EL, Chilcote TJ. Dynein structure and function. Journal of Cell Science. Supplement. 5: 189-96. PMID 2958487 DOI: 10.1242/jcs.1986.Supplement_5.12  1
1986 Holzbaur EL, Johnson KA. Rate of ATP synthesis by dynein. Biochemistry. 25: 428-34. PMID 2937451 DOI: 10.1021/BI00350A023  1
1983 Johnson KA, Shimizu T, Holzbaur EL. Kinetic evidence for multiple dynein heads: modeling the dissociation reaction. The Journal of Biological Chemistry. 258: 13847-8. PMID 6227619  1
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